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- Kaj Blennow
Kaj Blennow
Professor/överläkare
Sektionen för psykiatri och neurokemi-
Cerebrospinal fluid proteome profiling across the Alzheimer's disease continuum: a step towards solving the equation for
'X'
Sophia Weiner, Mathias Sauer, Laia Montoliu-Gaya, Andréa Lessa Benedet, Nicholas J. Ashton, Fernando Gonzalez-Ortiz, Joel Simrén, Nesrine Rahmouni, Cecile Tissot, Joseph Therriault, Stijn Servaes, Jenna Stevenson, Ville Leinonen, Tuomas Rauramaa, Mikko Hiltunen, Pedro Rosa-Neto, Kaj Blennow, Henrik Zetterberg, Johan Gobom
MOLECULAR NEURODEGENERATION - 2025 -
Associations Between Changes in Levels of Phosphorylated Tau and Severity of Cognitive Impairment in Early Alzheimer
Disease.
Fernando Gonzalez-Ortiz, Bjørn-Eivind Kirsebom, Yara Yakoub, Julia K Gundersen, Lene Pålhaugen, Knut Waterloo, Per Selnes, Jonas Alexander Jarholm, Berglind Gísladóttir, Arvid Rongve, Ragnhild Eide Skogseth, Geir Bråthen, Dag Aarsland, Michael Turton, Peter Harrison, Henrik Zetterberg, Sylvia Villeneuve, Tormod Fladby, Kaj Blennow
Neurology - 2025 -
Comparison of Plasma p-tau217 and [18F]FDG-PET for Identifying Alzheimer Disease in People With Early-Onset or Atypical
Dementia.
Kely Monica Quispialaya, Joseph Therriault, Antonio Aliaga, Andrea L Benedet, Nicholas J. Ashton, Thomas Karikari, Arthur Cassa Macedo, Nesrine Rahmouni, Cécile Tissot, Jaime Fernandez Arias, Yi-Ting Tina Wang, Lydia Trudel, Seyyed Ali Hosseini, Takashi Matsudaira, Tevy Chan, Tharick Pascoal, Brian Gilfix, Paolo Vitali, Eduardo R Zimmer, Karine Provost, Jean-Paul Soucy, Serge Gauthier, Henrik Zetterberg, Bertrand J Jean-Claude, Kaj Blennow, Pedro Rosa-Neto
Neurology - 2025 -
Cerebrospinal Fluid Biomarkers for Alzheimer Disease Among Patients With
Dementia
Tobias Skillbäck, Linus Jonsson, Ingmar Skoog, Kaj Blennow, Maria Eriksdotter, Henrik Zetterberg, Silke Kern
JAMA NEUROLOGY - 2025 -
Cognitive Phenotyping and Interpretation of Alzheimer Blood
Biomarkers
Vincent Bouteloup, Nicolas Villain, Jean Sebastien Vidal, Fernando Gonzalez-Ortiz, Idil Yuksekel, Cristiano Santos, Susanna Schraen-Maschken, Isabelle Pellegrin, Sylvain Lehmann, Kaj Blennow, Genevieve Chene, Olivier Hanon, Carole Dufouil, Vincent Planche
JAMA NEUROLOGY - 2025 -
Brain-Derived Tau as an Outcome Marker in Guillain-Barré Syndrome: A Retrospective Cohort
Study
Brynhildur Hafsteinsdottir, Fernando Gonzalez-Ortiz, Nina Gleisner, Ellen Alpsten, Jan Lycke, Igal Rosenstein, Lenka Novakova, Kaj Blennow, Tomas Bergström, Henrik Zetterberg, Markus Axelsson
EUROPEAN JOURNAL OF NEUROLOGY - 2025 -
Predictive value of neuronal markers for pituitary dysfunction following traumatic brain injury: A preliminary
study.
Aysa Hacioglu, Emre Urhan, Zuleyha Karaca, Ahmet Selcuklu, Halil Ulutabanca, Okkes Celil Gokcek, Bilal Yekeler, Kursad Unluhizarci, Kaj Blennow, Henrik Zetterberg, Fahrettin Kelestimur
Annales d'endocrinologie - 2025 -
Tau profiling across Alzheimer's disease staging reveals vulnerability to disease
pathophysiology
Gleb Bezgin, Tharick A. Pascoal, Joseph Therriault, Firoza Z. Lussier, Stijn Servaes, Min Su Kang, Melissa Savard, Cecile Tissot, Jenna Stevenson, Yi-Ting Wang, Julie Ottoy, Nesrine Rahmouni, Jaime Fernandez-Arias, Seyyed Ali Hosseini, Etienne Aumont, Brandon Hall, Nina Margherita Poltronetti, Vanessa Pallen, Andréa Lessa Benedet, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Thomas Karikari, Tatsuhiro Terada, Mira Chamoun, Sulantha Mathotaarachchi, Arthur Cassa Macedo, Alyssa Stevenson, Peter Kunach, Gassan Massarweh, Paolo Vitali, Jean-Paul Soucy, Yasser Iturria-Medina, Serge Gauthier, Pedro Rosa-Neto
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING - 2025 -
Dissection of blood-brain barrier dysfunction through CSF PDGFRβ and amyloid, tau, neuroinflammation, and synaptic CSF biomarkers in neurodegenerative
disorders
Agathe Vrillon, Nicholas J. Ashton, Elodie Bouaziz-Amar, Francois Mouton-Liger, Emmanuel Cognat, Julien Dumurgier, Matthieu Lilamand, Thomas K. Karikari, Vincent Prevot, Henrik Zetterberg, Kaj Blennow, Claire Paquet
EBIOMEDICINE - 2025 -
Novel insights into the molecular nature of neurofilament light polypeptide species in cerebrospinal
fluid
Bruno Becker, Johan Gobom, Gunnar Brinkmalm, Ulf Andreasson, Francisco J Meda, Henrik Zetterberg, Kaj Blennow
BRAIN COMMUNICATIONS - 2025 -
Proteomic analysis reveals distinct cerebrospinal fluid signatures across genetic frontotemporal dementia
subtypes
Aitana Sogorb-Esteve, Sophia Weiner, Joel Simrén, Imogen J. Swift, Martina Bocchetta, Emily G. Todd, David M. Cash, Arabella Bouzigues, Lucy L. Russell, Phoebe H. Foster, Eve Ferry-Bolder, John C. van Swieten, Lize C. Jiskoot, Harro Seelaar, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Daniela Galimberti, Rik Vandenberghe, Alexandre de Mendonca, Pietro Tiraboschi, Isabel Santana, Alexander Gerhard, Johannes Levin, Sandro Sorbi, Markus Otto, Florence Pasquier, Simon Ducharme, Chris R. Butler, Isabelle Le Ber, Elizabeth Finger, Maria Carmela Tartaglia, Mario Masellis, James B. Rowe, Matthis Synofzik, Fermin Moreno, Barbara Borroni, Kaj Blennow, Henrik Zetterberg, Jonathan D. Rohrer, Johan Gobom
SCIENCE TRANSLATIONAL MEDICINE - 2025 -
Plasma brain-derived tau correlates with cerebral infarct
volume.
Fernando Gonzalez-Ortiz, Lukas Holmegaard, Björn Andersson, Cecilia Brännmark, Christian Blomstrand, Henrik Zetterberg, Katarina Jood, Kaj Blennow, Christina Jern, Tara M Stanne
Journal of internal medicine - 2025 -
Clinical value of novel blood-based tau biomarkers in Creutzfeldt-Jakob
disease.
Giuseppe Mario Bentivenga, Fernando Gonzalez-Ortiz, Simone Baiardi, Bjørn-Eivind Kirsebom, Andrea Mastrangelo, Angela Mammana, Sabina Capellari, Tormod Fladby, Henrik Zetterberg, Kaj Blennow, Piero Parchi
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2025 -
Plasma p-tau217 in Alzheimer's disease: Lumipulse and ALZpath SIMOA head-to-head
comparison.
Andrea Pilotto, Virginia Quaresima, Chiara Trasciatti, Chiara Tolassi, Diego Bertoli, Cristina Mordenti, Alice Galli, Andrea Rizzardi, Salvatore Caratozzolo, Andrea Zancanaro, José Contador, Oskar Hansson, Sebastian Palmqvist, Giovanni de Santis, Henrik Zetterberg, Kaj Blennow, Duilio Brugnoni, Marc Suárez-Calvet, Nicholas J. Ashton, Alessandro Padovani
Brain : a journal of neurology - 2025 -
High CSF neurogranin level is related to lifetime reports of passive suicidal ideation in a population-based sample of older
adults.
Irma Rymo, Henrik Zetterberg, Kaj Blennow, Silke Kern, Ingmar Skoog, Simona Florentina Sacuiu, Margda Waern
Journal of psychiatric research - 2025 -
Plasma phosphorylated tau (p-tau231) and total tau (t-tau) as prognostic markers of neurological outcome after cardiac arrest - a multicentre
study.
Bergþóra Þorgeirsdóttir, Theodor Sievert, Anna Lybeck, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Hans Friberg, Attila Frigyesi
Resuscitation - 2025 -
Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus
erythematosus.
Marit Stockfelt, Agnes Torell, Iva Gunnarsson, Elisabet Svenungsson, Agneta Zickert, Maria Majcuk Sennström, Estelle Trysberg, Anders A Bengtsson, Andreas Jönsen, Helena Strevens, Christopher Sjöwall, Muna Saleh, Sofia Pihl, Dag Leonard, Lars Rönnblom, Tansim Akhter, Kaj Blennow, Henrik Zetterberg, Bo Jacobsson, Anna-Carin Lundell, Anna Rudin
Rheumatology (Oxford, England) - 2025 -
Plasma Alzheimer's disease biomarker variability: Amyloid-independent and amyloid-dependent
factors.
Eun Hye Lee, Sung Hoon Kang, Daeun Shin, Young Ju Kim, Henrik Zetterberg, Kaj Blennow, Fernándo González-Ortiz, Nicholas J. Ashton, Bo Kyoung Cheon, Heejin Yoo, Hongki Ham, Jihwan Yun, Jun Pyo Kim, Hee Jin Kim, Duk L Na, Hyemin Jang, Sang Won Seo
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2025 -
Disentangling relationships between Alzheimer's disease plasma biomarkers and established biomarkers in patients of tertiary memory
clinics.
Marina Bluma, Konstantinos Chiotis, Marco Bucci, Irina Savitcheva, Anna Matton, Miia Kivipelto, Andreas Jeromin, Giovanni de Santis, Guglielmo Di Molfetta, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Agneta Nordberg
EBioMedicine - 2025 -
Neuronal plasma biomarkers in acute ischemic
stroke
Julia K. Gundersen, Fernando Gonzalez-Ortiz, Thomas Karikari, Bjorn-Eivind Kirsebom, Katrin Mertes, Henrik Zetterberg, Hlin Kvartsberg, Ole Morten Ronning, Berglind Gisladottir, Kaj Blennow, Tormod Fladby
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM - 2025 -
Cerebrospinal fluid levels of NfM in relation to NfL and pNfH as prognostic markers in amyotrophic lateral
sclerosis
Jennie Olofsson, Sofia Bergstrom, Sara Mravinacova, Ulf Klappe, Linn Oijerstedt, Henrik Zetterberg, Kaj Blennow, Caroline Ingre, Peter Nilsson, Anna Manberg
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION - 2025 -
Sex differences in the trajectories of plasma biomarkers, brain atrophy, and cognitive decline relative to amyloid
onset
Cassandra M. Joynes, Murat Bilgel, Yang An, Abhay R. Moghekar, Nicholas J. Ashton, Przemyslaw R. Kac, Thomas Karikari, Kaj Blennow, Henrik Zetterberg, Madhav Thambisetty, Luigi Ferrucci, Susan M. Resnick, Keenan A. Walker
ALZHEIMERS & DEMENTIA - 2025 -
Peripheral innate immunophenotype in neurodegenerative disease: blood-based profiles and links to
survival
Alexandra Strauss, Peter Swann, Stacey L. Kigar, Rafailia Christou, Natalia Savinykh Yarkoni, Lorinda Turner, Alexander G. Murley, Leonidas Chouliaras, Noah Shapiro, Nicholas J. Ashton, George Savulich, W. Richard Bevan-Jones, Ajenthan Surendranthan, Kaj Blennow, Henrik Zetterberg, John T. O'Brien, James B. Rowe, Maura Malpetti
MOLECULAR PSYCHIATRY - 2025 -
Sex/gender effects of glial reactivity on preclinical Alzheimer's disease
pathology
Clara Vila-Castelar, Muge Akinci, Eleni Palpatzis, Pablo Aguilar-Dominguez, Gregory Operto, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Kaj Blennow, Henrik Zetterberg, Carles Falcon, Karine Fauria, Juan Domingo Gispert, Oriol Grau-Rivera, Marc Suarez-Calvet, Eider M. Arenaza-Urquijo
MOLECULAR PSYCHIATRY - 2025 -
Blood biomarkers of neuronal injury and astrocytic reactivity in electroconvulsive
therapy
Robert Sigström, Andreas Göteson, Erik Joas, Erik Palsson, Benny Liberg, Axel Nordenskjold, Kaj Blennow, Henrik Zetterberg, Mikael Landén
MOLECULAR PSYCHIATRY - 2025 -
The detection of GRN mutation carriers by progranulin blood protein levels from finger-stick
collection
Hanna Huber, Valentina Cantoni, Daniele Altomare, Lana Grötschel, Laia Montoliu-Gaya, Francisco J Meda, Hlin Kvartsberg, Ilenia Libri, Maria Sofia Cotelli, Henrik Zetterberg, Kaj Blennow, Barbara Borroni, Nicholas J. Ashton
ALZHEIMERS & DEMENTIA - 2025 -
Associations between the logical memory test story recall metrics and plasma biomarkers for Alzheimer's disease in individuals free of
dementia
Ainara Jauregi-Zinkunegi, Rachael E. Wilson, Rebecca E. Langhough, Nicholas J. Ashton, Kaj Blennow, Sterling C. Johnson, Henrik Zetterberg, Davide Bruno, Kimberly D. Mueller
CLINICAL NEUROPSYCHOLOGIST - 2025 -
Plasma phospho-tau217 for Alzheimer's disease diagnosis in primary and secondary care using a fully automated
platform
Sebastian Palmqvist, Noelle Warmenhoven, Federica Anastasi, Andrea Pilotto, Shorena Janelidze, Pontus Tideman, Erik Stomrud, Niklas Mattsson-Carlgren, Ruben Smith, Rik Ossenkoppele, Kübra Tan, Anna Dittrich, Ingmar Skoog, Henrik Zetterberg, Virginia Quaresima, Chiara Tolassi, Kina Hoglund, Duilio Brugnoni, Albert Puig-Pijoan, Aida Fernandez-Lebrero, Jose Contador, Alessandro Padovani, Mark Monane, Philip B. Verghese, Joel B. Braunstein, Silke Kern, Kaj Blennow, Nicholas J. Ashton, Marc Suarez-Calvet, Oskar Hansson
NATURE MEDICINE - 2025 -
Sex differences on tau, astrocytic, and neurodegenerative plasma
biomarkers
Jacob Labonte, Michael A. Sugarman, Erika Pettway, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Thomas Karikari, Hugo J. Aparicio, Brandon Frank, Yorghos Tripodis, Brett Martin, Joseph N. Palmisano, Eric G. Steinberg, Irene Simkin, Lindsay A. Farrer, Gyungah R. Jun, Katherine W. Turk, Andrew E. Budson, Maureen K. O'Connor, Rhoda Au, Lee E. Goldstein, Robert A. Stern, Thor D. Stein, Ann C. Mckee, Wei Qiao Qiu, Jesse Mez, Sarah J. Banks, Michael L. Alosco
JOURNAL OF ALZHEIMERS DISEASE - 2025 -
Grief and Economic Stressors by Sex, Gender, and
Education
Eleni Palpatzis, Muge Akinci, Marina Garcia-Prat, Kaj Blennow, Henrik Zetterberg, Clara Quijano-Rubio, Gwendlyn Kollmorgen, Norbert Wild, Juan Domingo Gispert, Marc Suarez-Calvet, Oriol Grau-Rivera, Karine Fauria, Anna Brugulat-Serrat, Gonzalo Sanchez-Benavides, Eider M. Arenaza-Urquijo
NEUROLOGY - 2025 -
Cost-effectiveness of diagnosing and treating patients with early Alzheimer's disease with anti-amyloid treatment in a clinical
setting
Anders Wimo, Ron Handels, Kaj Blennow, K. Bjorn-Eivind Kirsebom, Per Selnes, Jaka Bon, Andreja Emersic, Fernando Gonzalez-Ortiz, Milica Gregoric Kramberger, Anders Skoldunger, Andreja Speh, Santiago Timon-Reina, Ellen Vromen, Pieter Jelle Visser, Bengt Winblad, Tormod Fladby
JOURNAL OF ALZHEIMERS DISEASE - 2025 -
Higher plasma soluble TREM2 correlates with reduced cerebral tau accumulation in Alzheimer's
disease
Guoyu Lan, Anqi Li, Fernando Gonzalez-Ortiz, Jieqin Lv, Wenqing Ran, Yue Cai, Pan Sun, Lin Liu, Jie Yang, Laihong Zhang, Zhengbo He, Lili Fang, Xin Zhou, Yalin Zhu, Zhen Liu, Xiang Fan, Xuhui Chen, Linsen Xu, Qingyong Wang, Xinlu Wang, Kun Sun, Guanxun Cheng, Ying Han, Kaj Blennow, Lu Wang, Pengcheng Ran, Tengfei Guo
MOLECULAR PSYCHIATRY - 2025 -
Sex-specific modulation of FOLR1 and its cycle enzyme genes in Alzheimer's disease brain
regions
Cristina Sanfilippo, Paola Castrogiovanni, Rosa Imbesi, Michele Vecchio, Manlio Vinciguerra, Kaj Blennow, Henrik Zetterberg, Michelino Di Rosa
METABOLIC BRAIN DISEASE - 2025 -
Loneliness and biomarkers of brain pathology in people with subjective cognitive
decline
Mariola Zapater-Fajari, Isabel Crespo-Sanmiguel, Nira Cedres, Therese Rydberg Sterner, Lina Rydén, Simona Sacuiu, Margda Waern, Anna Zettergren, Henrik Zetterberg, Kaj Blennow, Silke Kern, Vanesa Hidalgo, Alicia Salvador, Eric Westman, Ingmar Skoog, Daniel Ferreira
SCIENTIFIC REPORTS - 2025 -
Plasma levels of the neuron damage markers brain-derived tau and glial fibrillary acidic protein in Lyme neuroborreliosis: A longitudinal
study
Mathilde Orbaek, Fernando Gonzalez-Ortiz, Rosa M. M. Gynthersen, Ase Bengaard Andersen, Kübra Tan, Ulf Andreasson, Kaj Blennow, Helene Mens, Henrik Zetterberg, Anne-Mette Lebech
TICKS AND TICK-BORNE DISEASES - 2025 -
Increased Cerebrospinal Fluid Angiotensin-Converting Enzyme 2 Fragments as a Read-Out of Brain Infection in Patients With COVID-19
Encephalopathy
Matthew P. Lennol, Maria-Salud Garcia-Ayllon, Carlos Aviles-Granados, Chiara Trasciatti, Chiara Tolassi, Virginia Quaresima, Davide Arici, Viviana Cristillo, Irene Volonghi, Francesca Caprioli, Valeria De Giuli, Sara Mariotto, Sergio Ferrari, Gianluigi Zanusso, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Alessandro Padovani, Andrea Pilotto, Javier Saez-Valero
JOURNAL OF INFECTIOUS DISEASES - 2025 -
Cardiovascular rate pressure product is associated with NfL in older adults at risk for
AD
Chinenye C. Odo, Joe Strong, Sarah R. Lose, Yue Ma, Catherine L. Gallagher, Barbara B. Bendlin, Henrik Zetterberg, Kaj Blennow, Cynthia M. Carlsson, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Nathaniel A. Chin, Sanjay Asthana, Sterling C. Johnson, Jacqueline Pontes Monteiro, Ozioma C. Okonkwo
ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING - 2025 -
Data-driven evaluation of suitable immunogens for improved antibody
selection
Katharina Waury, Hlin Kvartsberg, Henrik Zetterberg, Kaj Blennow, Charlotte E. Teunissen, Sanne Abeln
PROTEIN SCIENCE - 2025 -
Associations between cerebrospinal fluid synaptic protein biomarkers and cognitive function in bipolar
disorder
Ulla Knorr, Anja Hviid Simonsen, Johanna Nilsson, Ann Brinkmalm, Henrik Zetterberg, Kaj Blennow, Mark Bech Knudsen, Julie Forman, Kamilla Woznica Miskowiak, Steen Gregers Hasselbalch, Lars Vedel Kessing
JOURNAL OF PSYCHIATRIC RESEARCH - 2025 -
Sex Differences in Apolipoprotein E and Alzheimer Disease Pathology Across
Ancestries
Xiaoyi Xu, Jiseon Kwon, Ruiqi Yan, Catherine Apio, Soomin Song, Gyujin Heo, Qijun Yang, Jigyasha Timsina, Menghan Liu, John Budde, Kaj Blennow, Henrik Zetterberg, Alberto Lleo, Agustin Ruiz, Jose Luis Molinuevo, Virginia Man-Yee Lee, Yuetiva Deming, Amanda J. Heslegrave, Tim J. Hohman, Pau Pastor, Elaine R. Peskind, Marilyn S. Albert, John C. Morris, Taesung Park, Carlos Cruchaga, Yun Ju Sung
JAMA NETWORK OPEN - 2025 -
Biofluid-based staging of Alzheimer's
disease
Juan Lantero Rodriguez, Laia Montoliu-Gaya, Nicholas J. Ashton, Ilaria Pola, Joseph Therriault, Nesrine Rahmouni, Wagner Scheeren Brum, Stijn Servaes, Jenna Stevenson, Guglielmo Di Molfetta, Burak Arslan, Jesse Klostranec, Paolo Vitali, Maxime Montembeault, Serge Gauthier, Cecile Tissot, Arthur C. Macedo, Tharick A. Pascoal, Andreas Jeromin, Johan Gobom, Kaj Blennow, Henrik Zetterberg, Pedro Rosa-Neto, Andrea L Benedet
ACTA NEUROPATHOLOGICA - 2025 -
Loneliness and Biomarkers of Alzheimer's Disease, Axonal Damage, and Astrogliosis: A Coordinated Analysis of Two Longitudinal
Cohorts
Antonio Terracciano, Keenan A. Walker, Yang An, Murat Bilgel, Angelina R. Sutin, Martina Luchetti, Selin Karakose, Yannick Stephan, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Thomas Karikari, Przemyslaw R. Kac, Abhay R. Moghekar, Madhav Thambisetty, Luigi Ferrucci, Susan M. Resnick
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES - 2025 -
Calcium modulating ligand confers risk for Parkinson's disease and impacts
lysosomes
Hanwen Zhang, Daniel Kargilis, Thomas Tropea, John Robinson, Junchao Shen, Eliza M. Brody, Ann Brinkmalm, Simon Sjödin, Adama J. Berndt, Marc Carceles-Cordon, Eunran Suh, Vivianna M. Van Deerlin, Kaj Blennow, Daniel Weintraub, Edward B. Lee, Henrik Zetterberg, Alice S. Chen-Plotkin
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY - 2025 -
Associations between moderate-to-vigorous physical activity, p-tau181, and cognition in healthy older adults with memory complaints: a secondary analysis from the
MAPT
Jeremy Raffin, Kaj Blennow, Yves Rolland, Christelle Cantet, Sophie Guyonnet, Bruno Vellas, Philipe de Souto Barreto
LANCET HEALTHY LONGEVITY - 2025 -
Tau levels in platelets isolated from Huntington's disease patients serve as a biomarker of disease
severity
Melanie Alpaugh, Juan Lantero Rodriguez, Andrea L Benedet, Uriel Manseau, Martine Boutin, Massimo Maiuri, Helena L. Denis, Maria Masnata, Shaline V. Fazal, Sylvain Chouinard, Pedro Rosa-Neto, Roger A. Barker, Kaj Blennow, Henrik Zetterberg, Richard Labib, Francesca Cicchetti
JOURNAL OF NEUROLOGY - 2025 -
Soluble cerebral Aβ protofibrils link Aβ plaque pathology to changes in CSF Aβ<sub>42</sub>/Aβ<sub>40</sub> ratios, neurofilament light and tau in Alzheimer's disease model
mice
Emelie Andersson, Nils Lindblom, Shorena Janelidze, Gemma Salvado, Eleni Gkanatsiou, Linda Soderberg, Christer Moller, Lars Lannfelt, Junyue Ge, Joerg Hanrieder, Kaj Blennow, Tomas Deierborg, Niklas Mattsson-Carlgren, Henrik Zetterberg, Gunnar Gouras, Oskar Hansson
NATURE AGING - 2025 -
Physical Activity, Alzheimer Plasma Biomarkers, and
Cognition
Seung Ae Kim, Daeun Shin, Hongki Ham, Yeshin Kim, Yuna Gu, Hee Jin Kim, Duk L. Na, Henrik Zetterberg, Kaj Blennow, Sang Won Seo, Hyemin Jang
JAMA NETWORK OPEN - 2025 -
Association between BrainAGE and Alzheimer's disease
biomarkers
Yousaf Abughofah, Rachael Deardorff, Aaron Vosmeier, Savannah Hottle, Jeffrey L. Dage, Desarae Dempsey, Liana G. Apostolova, Jared Brosch, David Clark, Martin Farlow, Tatiana Foroud, Sujuan Gao, Sophia Wang, Henrik Zetterberg, Kaj Blennow, Andrew J. Saykin, Shannon L. Risacher
ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING - 2025 -
A head-to-head comparison of plasma biomarkers to detect Alzheimer's disease in a memory
clinic
Federica Anastasi, Aida Fernandez-Lebrero, Nicholas J. Ashton, Paula Ortiz-Romero, Javier Torres-Torronteras, Armand Gonzalez-Escalante, Marta Mila-Aloma, Jose Contador, Greta Garcia-Escobar, Rosa Maria Manero-Borras, Irene Navalpotro-Gomez, Esther Jimenez-Moyano, Aparna Sahajan, Qinyu Hao, Bingqing Zhang, Andreas Jeromin, Nathalie Le Bastard, Alicia Nadal, Tahmine Mousavi, Gwendlyn Kollmorgen, Margherita Carboni, Oriol Grau-Rivera, Henrik Zetterberg, Marta del Campo, Kaj Blennow, Albert Puig-Pijoan, Marc Suarez-Calvet
ALZHEIMERS & DEMENTIA - 2025 -
Evaluation of two plasma-based proteotyping assays against <i>APOE</i> ε4 genotyping in a memory clinic setting: The Gothenburg H70 Clinical
Studies
Anna Dittrich, Kaj Blennow, Kübra Tan, Andrea L Benedet, Ingmar Skoog, Kina Hoglund, Nicholas J. Ashton, Henrik Zetterberg, Silke Kern
ALZHEIMERS & DEMENTIA - 2025 -
Plasma p-tau217 identifies cognitively normal older adults who will develop cognitive impairment in a 10-year
window
Yara Yakoub, Fernando Gonzalez-Ortiz, Nicholas J. Ashton, Christine Dery, Cherie Strikwerda-Brown, Frederic St-Onge, Valentin Ourry, Michael Schöll, Maiya R. Geddes, Simon Ducharme, Maxime Montembeault, Pedro Rosa-Neto, Jean-Paul Soucy, John C. S. Breitner, Henrik Zetterberg, Kaj Blennow, Judes Poirier, Sylvia Villeneuve
ALZHEIMERS & DEMENTIA - 2025 -
Amyloid is associated with accelerated atrophy in cognitively unimpaired
individuals
Henry Gilreath Stephenson, Tobey J. Betthauser, Rebecca Langhough, Erin Jonaitis, Lianlian Du, Carol Van Hulle, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Nathaniel A. Chin, Ozioma C. Okonkwo, Cynthia M. Carlsson, Sanjay Asthana, Sterling C. Johnson, Kaj Blennow, Henrik Zetterberg, Barbara B. Bendlin
ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING - 2025 -
The impact of kidney function on Alzheimer's disease blood biomarkers: implications for predicting amyloid-β
positivity.
Burak Arslan, Wagner Scheeren Brum, Ilaria Pola, Joseph Therriault, Nesrine Rahmouni, Jenna Stevenson, Stijn Servaes, Kübra Tan, Paolo Vitali, Maxime Montembeault, Jesse Klostranec, Arthur C Macedo, Cecile Tissot, Serge Gauthier, Juan Lantero Rodriguez, Eduardo R Zimmer, Kaj Blennow, Henrik Zetterberg, Pedro Rosa-Neto, Andrea L Benedet, Nicholas J. Ashton
Alzheimer's Research & Therapy - 2025 -
Machine learning prediction of tau-PET in Alzheimer's disease using plasma, MRI, and clinical
data
Linda Karlsson, Jacob Vogel, Ida Arvidsson, Kalle Astrom, Olof Strandberg, Jakob Seidlitz, Richard A. I. Bethlehem, Erik Stomrud, Rik Ossenkoppele, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Sebastian Palmqvist, Ruben Smith, Shorena Janelidze, Renaud La Joie, Gil D. Rabinovici, Alexa Pichet Binette, Niklas Mattsson-Carlgren, Oskar Hansson
ALZHEIMERS & DEMENTIA - 2025 -
Automatic quantification of syntactic complexity in natural spontaneous speech of people with primary progressive
aphasia
Galit Agmon, Sunghye Cho, Sharon Ash, Katheryn A. Q. Cousins, Kaj Blennow, Henrik Zetterberg, Leslie M. Shaw, Sameer Pradhan, Yoon Duk Kim, Mark Y. Liberman, David J. Irwin, Naomi Nevler
APHASIOLOGY - 2025 -
Predicting survival rate by plasma biomarkers and clinical variables in syndromes associated with frontotemporal lobar
degeneration.
Maria Sofia Cotelli, Barbara Tarantino, Kübra Tan, Hanna Huber, Valentina Cantoni, Valeria Bracca, Roberto Gasparotti, Enrico Premi, Giancarlo Logroscino, Andrea L Benedet, Kaj Blennow, Henrik Zetterberg, Mario Grassi, Nicholas J. Ashton, Barbara Borroni
Alzheimer's & Dementia - 2025 -
Synaptosomal-Associated Protein 25 kDA (SNAP-25) Levels in Cerebrospinal Fluid: Implications for Alzheimer's Disease Diagnosis and
Monitoring
Sofia Hjorth Wolner, Helena Sophia Gleerup, Christian Sandoe Musaeus, Peter Hogh, Nicholas J. Ashton, Ann Brinkmalm, Johanna Nilsson, Lana Grötschel, Henrik Zetterberg, Kaj Blennow, Steen Gregers Hasselbalch, Anne Byriel Walls, Anja Hviid Simonsen
SYNAPSE - 2025 -
Differential roles of Alzheimer's disease plasma biomarkers in stepwise biomarker-guided
diagnostics
Hyemin Jang, Daeun Shin, Heejin Yoo, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J. Ashton, Theresa A. Day, Eun Hye Lee, Jihwan Yun, Duk L. Na, Hee Jin Kim, Sung Hoon Kang, Ko Woon Kim, Si Eun Kim, Yeo Jin Kim, Yeshin Kim, Jaeho Kim, Chi-Hun Kim, Min Young Chun, Na Yeon Jung, Soo Hyun Cho, Jun Pyo Kim, Sang Won Seo
ALZHEIMERS & DEMENTIA - 2025 -
Subtypes of brain change in aging and their associations with cognition and Alzheimer's disease
biomarkers.
Elettra Capogna, Øystein Sørensen, Leiv Otto Watne, James Roe, Marie Strømstad, Ane Victoria Idland, Nathalie Bodd Halaas, Kaj Blennow, Henrik Zetterberg, Kristine Beate Walhovd, Anders Martin Fjell, Didac Vidal-Piñeiro
NEUROBIOLOGY OF AGING - 2025 -
Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer's disease in
humans
Bryan J. Neth, Kevin Huynh, Corey Giles, Tingting Wang, Natalie A. Mellett, Thy Duong, Colette Blach, Leyla Schimmel, Thomas C. Register, Kaj Blennow, Henrik Zetterberg, Richa Batra, Annalise Schweickart, Amanda Hazel Dilmore, Cameron Martino, Matthias Arnold, Jan Krumsiek, Xianlin Han, Pieter C. Dorrestein, Rob Knight, Peter J. Meikle, Suzanne Craft, Rima Kaddurah-Daouk
Communications Medicine - 2025 -
Opening for a new type of drug for Alzheimer’s
Disease.
Tohidul Islam, Kaj Blennow, Thomas Karikari
Press release, University of Gothenburg - 2025 -
Identify biological Alzheimer's disease using a novel nucleic acid-linked protein
immunoassay
Yi-Ting Wang, Nicholas J. Ashton, Joseph Therriault, Andrea L Benedet, Arthur C. Macedo, Ilaria Pola, Etienne Aumont, Guglielmo Di Molfetta, Jaime Fernandez-Arias, Kübra Tan, Nesrine Rahmouni, Stijn Johannes G. Servaes, Richard Isaacson, Tevy Chan, Seyyed Ali Hosseini, Cecile Tissot, Sulantha Mathotaarachchi, Jenna Stevenson, Firoza Z. Lussier, Tharick A. Pascoal, Serge Gauthier, Kaj Blennow, Henrik Zetterberg, Pedro Rosa-Neto
Brain Communications - 2025 -
Inflammation biomarkers and Alzheimer's disease: A pilot study using
NULISAseq
Guglielmo Di Molfetta, Ilaria Pola, Kübra Tan, Richard Isaacson, Kaj Blennow, Nicholas J. Ashton, Andrea L Benedet, Henrik Zetterberg
Alzheimer's & Dementia - 2025 -
Soluble Aβ pathology predicts neurodegeneration and cognitive decline independently on p-tau in the earliest Alzheimer's <i>continuum</i>: Evidence across two independent
cohorts
Raffaele Cacciaglia, Carles Falcon, Gonzalo Sanchez Benavides, Anna Brugulat-Serrat, Marta Mila Aloma, Marc Suarez Calvet, Jose Luis Molinuevo, Karine Fauria, Carolina Minguillon, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Kaj Blennow, Henrik Zetterberg, Luigi Lorenzini, Alle Meije Wink, Silvia Ingala, Frederik Barkhof, Craig W. Ritchie, Juan Domingo Gispert
ALZHEIMERS & DEMENTIA - 2025 -
Serum NFL and neuropsychological performance over '-8 years in women with and without HIV: a longitudinal repeated measures
study
Deborah R. Gustafson, Xuantao Li, Alison E. Baird, Henrik Zetterberg, Kaj Blennow, Jinbing Zhang, Amanda Blair Spence, Pauline Maki, Anjali Sharma, Kathleen Weber, Recai Yucel
ECLINICALMEDICINE - 2025 -
Biomarker treatment effects in two phase 3 trials of
gantenerumab
Tobias Bittner, Matteo Tonietto, Gregory Klein, Anton Belusov, Vittorio Illiano, Nicola Voyle, Paul Delmar, Marzia A. Scelsi, Susanna Gobbi, Erica Silvestri, Muhamed Barakovic, Antonio Napolitano, Christopher Galli, Maryam Abaei, Kaj Blennow, Frederik Barkhof
ALZHEIMERS & DEMENTIA - 2025 -
Phospho-tau serine-262 and serine-356 as biomarkers of pre-tangle soluble tau assemblies in Alzheimer's
disease.
Tohidul Islam, Emily Hill, Eric E Abrahamson, Stijn Servaes, Denis S Smirnov, Xuemei Zeng, Anuradha Sehrawat, Yijun Chen, Przemysław R Kac, Hlin Kvartsberg, Maria Olsson, Emma Sjons, Fernando Gonzalez-Ortiz, Joseph Therriault, Cécile Tissot, Ivana Del Popolo, Nesrine Rahmouni, Abbie Richardson, Victoria Mitchell, Henrik Zetterberg, Tharick A Pascoal, Tammaryn Lashley, Mark J Wall, Douglas Galasko, Pedro Rosa-Neto, Milos D Ikonomovic, Kaj Blennow, Thomas K Karikari
Nature Medicine - 2025 -
Cerebral Microbleeds and Amyloid Pathology Estimates From the Amyloid Biomarker
Study
Julie E. Oomens, Veerle van Gils, Stephanie J. B. Vos, Whitney M. Freeze, Nancy N. Maserejian, Gioacchino Curiale, Cai Gillis, Merce Boada, Wiesje M. van der Flier, Jakub Hort, Sterling C. Johnson, Alberto Lleo, Inez H. Ramakers, Karen M. Rodrigue, Pascual Sanchez-Juan, Marie Sarazin, Nikolaos Scarmeas, Henrik Zetterberg, Daniel Alcolea, Frederik Barkhof, Kaj Blennow, Michel Bottlaender, Anouk den Braber, Jiri Cerman, Marta Drake-Perez, Juan Fortea, Ron Handels, Silvia Ingala, Julio F. Jimenez-Bonilla, Stratos Karavasilis, Julien Lagarde, Nienke Legdeur, Luigi Lorenzini, Marta Marquie, Justine E. F. Moonen, Pauline Olivieri, Adelina Orellana, Rik Ossenkoppele, Leonardo A. Rivera-Rivera, Eloy Rodriguez-Rodriguez, Agustin Ruiz Laza, Charlotte E. Teunissen, Betty M. Tijms, Giorgos Velonakis, Frans R. J. Verhey, Pieter Jelle Visser, Willemijn J. Jansen
JAMA NETWORK OPEN - 2025 -
Dispersion-based cognitive intra-individual variability in former American football players: Association with traumatic encephalopathy syndrome, repetitive head impacts, and
biomarkers
Caroline Altaras, Monica T. Ly, Olivia Schultz, William B. Barr, Sarah J. Banks, Jennifer V. Wethe, Yorghos Tripodis, Charles H. Adler, Laura J. Balcer, Charles Bernick, Henrik Zetterberg, Kaj Blennow, Nicholas Ashton, Elaine Peskind, Robert C. Cantu, Michael J. Coleman, Alexander P. Lin, Inga K. Koerte, Sylvain Bouix, Daniel Daneshvar, David W. Dodick, Yonas E. Geda, Douglas L. Katz, Jason L. Weller, Jesse Mez, Joseph N. Palmisano, Brett Martin, Jeffrey L. Cummings, Eric M. Reiman, Martha E. Shenton, Robert A. Stern, Michael L. Alosco
CLINICAL NEUROPSYCHOLOGIST - 2025 -
Evaluating plasma biomarkers NfL, GFAP, GDF15, and FGF21 as indicators of disease severity in Charcot-Marie Tooth
patients
Dace Pretkalnina, Elizabete Kenina, Linda Gailite, Dmitrijs Rots, Kaj Blennow, Henrik Zetterberg, Viktorija Kenina
FRONTIERS IN NEUROLOGY - 2025 -
Tau Aggregates in Cerebrospinal Fluid: A Promising Biomarker for Neurodegenerative
Diseases
Tohidul Islam, Kaj Blennow, Thomas Karikari
Alzheimer's & Dementia - 2025 -
Functional and Cognitive Impairment in Patients with Relapsing-Remitting Multiple Sclerosis: Cognitive Tests and Plasma Neurofilament Light Chain
Levels
Elina Polunosika, Joel Simrén, Arta Akmene, Nikita Klimovskis, Kaj Blennow, Daina Pastare, Henrik Zetterberg, Renars Erts, Guntis Karelis
MEDICINA-LITHUANIA - 2025 -
Novel synaptic markers predict early tau pathology and cognitive deficit in an asymptomatic population at risk of Alzheimer's
disease
Jiarui Ao, Cynthia Picard, Daniel Auld, Henrik Zetterberg, Ann Brinkmalm, Kaj Blennow, Sylvia Villeneuve, John C. S. Breitner, Judes Poirier
MOLECULAR PSYCHIATRY - 2025 -
Vascular endothelial growth factor receptor-1 (FLT1) interactions with amyloid-beta in Alzheimer's disease: A putative biomarker of amyloid-induced vascular
damage
Rebecca L. Winfree, Emma Nolan, Kaj Blennow, Henrik Zetterberg, Katherine A. Gifford, Kimberly R. Pechman, Julie Schneider, David A. Bennett, Vladislav A. Petyuk, Angela L. Jefferson, Timothy J. Hohman
NEUROBIOLOGY OF AGING - 2025 -
Plasma N-terminal tau fragment is an amyloid-dependent biomarker in Alzheimer's
disease
Guoyu Lan, Laihong Zhang, Anqi Li, Wenqing Ran, Jieqin Lv, Fernando Gonzalez-Ortiz, Yue Cai, Pan Sun, Lin Liu, Jie Yang, Zhengbo He, Lili Fang, Xin Zhou, Yalin Zhu, Zhen Liu, Xuhui Chen, Xiang Fan, Dai Shi, Chenghui Ye, Linsen Xu, Qingyong Wang, Kaj Blennow, Guanxun Cheng, Pengcheng Ran, Lu Wang, Tengfei Guo
ALZHEIMERS & DEMENTIA - 2025 -
Association between herpes simplex virus infection and Alzheimer's disease biomarkers: analysis within the MAPT
trial
Morgane Linard, Isabelle Garrigue, Bruno Vellas, Nicola Coley, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Pierre Payoux, Anne-Sophie Salabert, Jean-Francois Dartigues, Joachim Mazere, Sandrine Andrieu, Catherine Helmer
SCIENTIFIC REPORTS - 2025 -
Clinical utility of plasma p-tau217 in identifying abnormal brain amyloid burden in an Asian cohort with high prevalence of concomitant cerebrovascular
disease
Joyce R. Chong, Saima Hilal, Boon Yeow Tan, Narayanaswamy Venketasubramanian, Michael Schöll, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Christopher P. Chen, Mitchell K. P. Lai
ALZHEIMERS & DEMENTIA - 2025 -
Short-term variability of Alzheimer's disease plasma biomarkers in a mixed memory clinic
cohort
Frederikke Kragh Clemmensen, Mathias Holsey Gramkow, Anja Hviid Simonsen, Nicholas J. Ashton, Hanna Huber, Kaj Blennow, Henrik Zetterberg, Gunhild Waldemar, Steen Gregers Hasselbalch, Kristian Steen Frederiksen
ALZHEIMERS RESEARCH & THERAPY - 2025 -
Single- versus two-test criteria for cognitive impairment: associations with CSF and imaging markers in former American football
players
Monica T. Ly, Caroline Altaras, Yorghos Tripodis, Charles H. Adler, Laura J. Balcer, Charles Bernick, Henrik Zetterberg, Kaj Blennow, Elaine R. Peskind, Sarah J. Banks, William B. Barr, Jennifer V. Wethe, Steve Lenio, Mark W. Bondi, Lisa M. Delano-Wood, Robert C. Cantu, Michael J. Coleman, David W. Dodick, Jesse Mez, Daniel H. Daneshvar, Joseph N. Palmisano, Brett Martin, Alexander P. Lin, Inga K. Koerte, Sylvain Bouix, Jeffrey L. Cummings, Eric M. Reiman, Martha E. Shenton, Robert A. Stern, Michael L. Alosco
CLINICAL NEUROPSYCHOLOGIST - 2025 -
Polygenic risk scores for atrial fibrillation and heart failure and the risk of stroke and
dementia
Lina Rydén, Nazib Seidu, Hanna Wetterberg, Jenna Najar, Margda Waern, Silke Kern, Kaj Blennow, Henrik Zetterberg, Ingmar Skoog, Anna Zettergren
BRAIN COMMUNICATIONS - 2025 -
Plasma biomarkers of amyloid, tau, astrogliosis, and axonal injury in a mixed memory clinic
cohort
Helena Sophia Gleerup, Anja Hviid Simonsen, Lana Grötschel, Mathias Holsey Gramkow, Peter Hogh, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Steen Gregers Hasselbalch
ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING - 2025 -
Plasma p-tau and neurofilament/p-tau ratio in differentiating Alzheimer's disease from syndromes associated with frontotemporal lobar
degeneration
Alberto Benussi, Hanna Huber, Kübra Tan, Valentina Cantoni, Jasmine Rivolta, Maria Sofia Cotelli, Andrea L Benedet, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Barbara Borroni
ALZHEIMERS & DEMENTIA - 2025 -
Menopausal hormone therapy is associated with worse levels of Alzheimer's disease biomarkers in APOE ε4-carrying women: An observational
study
Ainara Jauregi-Zinkunegi, Carey E. Gleason, Barbara Bendlin, Ozioma Okonkwo, Bruce P. Hermann, Kaj Blennow, Henrik Zetterberg, Eef Hogervorst, Sterling C. Johnson, Rebecca Langhough, Kimberly D. Mueller, Davide Bruno
ALZHEIMERS & DEMENTIA - 2025 -
Blood-Based Biomarkers and Risk of Onset of Mild Cognitive Impairment Over the Short and Long
Term.
Anja Soldan, Corinne Pettigrew, Jiangxia Wang, Marilyn S Albert, Kaj Blennow, Tobias Bittner, Abhay Moghekar
Neurology - 2025 -
Neuroinflammation in Parkinson's disease: A study with [<SUP>11</SUP>C]PBR28 PET and cerebrospinal fluid
markers
H. Al-Abdulrasul, R. Ajalin, J. Tuisku, Henrik Zetterberg, Kaj Blennow, T. Vahlberg, L. Ekblad, S. Helin, S. Forsback, J. O. Rinne
PARKINSONISM & RELATED DISORDERS - 2025 -
The CSF p-tau/β-amyloid 42 ratio correlates with brain structure and fibrillary β-amyloid deposition in cognitively unimpaired individuals at the earliest stages of pre-clinical Alzheimer's
disease.
Raffaele Cacciaglia, Mahnaz Shekari, Gemma Salvadó, Marta Milà-Alomà, Carles Falcon, Gonzalo Sánchez-Benavides, Carolina Minguillón, Karine Fauria, Oriol Grau-Rivera, José Luis Molinuevo, Kaj Blennow, Henrik Zetterberg, Frances-Catherine Quevenco, Marc Suárez-Calvet, Juan Domingo Gispert
Brain Communications - 2025 -
A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker
tests.
Noëlle Warmenhoven, Gemma Salvadó, Shorena Janelidze, Niklas Mattsson-Carlgren, Divya Bali, Anna Orduña Dolado, Hartmuth Kolb, Gallen Triana-Baltzer, Nicolas R Barthélemy, Suzanne E Schindler, Andrew J Aschenbrenner, Cyrus A Raji, Tammie L S Benzinger, John C Morris, Laura Ibanez, Jigyasha Timsina, Carlos Cruchaga, Randall J Bateman, Nicholas J. Ashton, Burak Arslan, Henrik Zetterberg, Kaj Blennow, Alexa Pichet Binette, Oskar Hansson
Brain : a journal of neurology - 2024 -
Stability of bilirubin and oxyhaemoglobin in cerebrospinal
fluid.
Marcus Clarin, Alexandra Hellberg, Kaj Blennow, Ulf Andreasson, Henrik Zetterberg
Scandinavian journal of clinical and laboratory investigation - 2024 -
Blood inflammation relates to neuroinflammation and survival in frontotemporal lobar
degeneration
Maura Malpetti, Peter Swann, Kamen A. Tsvetanov, Leonidas Chouliaras, Alexandra Strauss, Tanatswa Chikaura, Alexander G. Murley, Nicholas J. Ashton, Peter Barker, Peter Simon Jones, Tim D. Fryer, Young T. Hong, Thomas E. Cope, George Savulich, Duncan Street, William Richard Bevan-Jones, Timothy Rittman, Kaj Blennow, Henrik Zetterberg, Franklin Aigbirhio, John T. O'Brien, James B. Rowe
BRAIN - 2024 -
Development of an immunoassay for the quantification of Tau aggregates in Alzheimer´s
disease
Tohidul Islam, Thomas Karikari, Henrik Zetterberg, Kaj Blennow
Alzheimer's & Parkinson's Diseases - 2024 -
Cerebrospinal Fluid Tau Amplification and Immunoassay: A Combinational Approach in Tauopathy
Diagnosis
Tohidul Islam, Thomas Karikari, Kaj Blennow
Society for CSF analysis and clinical neurochemistry - 2024 -
The Alzheimer's Association Global Biomarker Standardization Consortium (GBSC) plasma phospho-tau Round Robin
study.
Nicholas J. Ashton, Ashvini Keshavan, Wagner Scheeren Brum, Ulf Andreasson, Burak Arslan, Mathias Droescher, Stefan Barghorn, Jeroen Vanbrabant, Charlotte Lambrechts, Maxime Van Loo, Erik Stoops, Shweta Iyengar, HaYeun Ji, Xiaomei Xu, Alex Forrest-Hay, Bingqing Zhang, Yuling Luo, Andreas Jeromin, Manu Vandijck, Nathalie Le Bastard, Hartmuth Kolb, Gallen Triana-Baltzer, Divya Bali, Shorena Janelidze, Shieh-Yueh Yang, Catherine Demos, Daniel Romero, George Sigal, Jacob Wohlstadter, Kishore Malyavantham, Meenakshi Khare, Alexander Jethwa, Laura Stoeckl, Johan Gobom, Przemysław R Kac, Fernando Gonzalez-Ortiz, Laia Montoliu-Gaya, Oskar Hansson, Robert A Rissman, Maria C Carillo, Leslie M Shaw, Kaj Blennow, Jonathan M Schott, Henrik Zetterberg
medRxiv : the preprint server for health sciences - 2024 -
Amyloid-β positivity is less prevalent in cognitively unimpaired KLOTHO KL-VS
heterozygotes.
Noah Cook, Ira Driscoll, Julian M Gaitán, Matthew Glittenberg, Tobey J Betthauser, Cynthia M Carlsson, Sterling C Johnson, Sanjay Asthana, Henrik Zetterberg, Kaj Blennow, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Dena B Dubal, Ozioma C Okonkwo
Journal of Alzheimer's disease : JAD - 2024 -
Plasma neurofilament light outperforms glial fibrillary acidic protein in differentiating behavioural variant frontotemporal dementia from primary psychiatric
disorders.
Dhamidhu Eratne, Matthew J Y Kang, Courtney Lewis, Christa Dang, Charles Malpas, Suyi Ooi, Amy Brodtmann, David Darby, Henrik Zetterberg, Kaj Blennow, Michael Berk, Olivia Dean, Chad Bousman, Naveen Thomas, Ian Everall, Chris Pantelis, Cassandra Wannan, Claudia Cicognola, Oskar Hansson, Shorena Janelidze, Alexander F Santillo, Dennis Velakoulis
Journal of the neurological sciences - 2024 -
Sensitivity and specificity of a seed amplification assay for diagnosis of multiple system atrophy: a multicentre cohort
study.
Yihua Ma, Carly M Farris, Sandrina Weber, Sebastian Schade, Hieu Nguyen, Alexandra Pérez-Soriano, Darly M Giraldo, Manel Fernández, Marta Soto, Ana Cámara, Celia Painous, Esteban Muñoz, Francesc Valldeoriola, Maria J Martí, Jordi Clarimon, Pekka Kallunki, Thong Chi Ma, Roy N Alcalay, Bárbara Fernandes Gomes, Kaj Blennow, Henrik Zetterberg, Julius Constantinescu, David Mengel, Vaibhavi Kadam, Piero Parchi, Kathrin Brockmann, Thomas F Tropea, Andrew Siderowf, Matthis Synofzik, Un Jung Kang, Yaroslau Compta, Per Svenningsson, Brit Mollenhauer, Luis Concha-Marambio
The Lancet. Neurology - 2024 -
Cerebrospinal fluid biomarker panel for synaptic dysfunction in a broad spectrum of neurodegenerative
diseases.
Johanna Nilsson, Alexa Pichet Binette, Sebastian Palmqvist, Wagner Scheeren Brum, Shorena Janelidze, Nicholas J. Ashton, Nicola Spotorno, Erik Stomrud, Johan Gobom, Henrik Zetterberg, Ann Brinkmalm, Kaj Blennow, Oskar Hansson
Brain - 2024 -
p75 neurotrophin receptor modulation in mild to moderate Alzheimer disease: a randomized, placebo-controlled phase 2a
trial
Hayley R. C. Shanks, Kewei Chen, Eric M. Reiman, Kaj Blennow, Jeffrey L. Cummings, Stephen M. Massa, Frank M. Longo, Anne Borjesson-Hanson, Manfred Windisch, Taylor W. Schmitz
Nature Medicine - 2024 -
1- versus 2-test criteria for cognitive impairment and associations with CSF and imaging markers in former American football
players
Monica T. Ly, Caroline Altaras, Yorghos Tripodis, Charles Adler, Laura Balcer, Charles B. Bernick, Henrik Zetterberg, Kaj Blennow, Elaine R. Peskind, Sarah Banks, William B. Barr, Jennifer V. Wethe, Mark W. Bondi, Lisa Delano-Wood, Robert C. Cantu, Michael J. Coleman, David W. Dodick, Jesse Mez, Joseph N. Palmisano, Brett Martin, Alexander P. Lin, Sylvain Bouix, Jeffrey L. Cummings, Eric M. Reiman, Martha E. Shenton, Robert A. Stern, Michael L. Alosco
Alzheimer's & Dementia - 2024 -
Robust Symptomatic Subtypes of Typical Alzheimer’s Disease Characterized by Differential Neuropathological Patterns and Functional
Decline
Hussein Zalzale, Pamela C.L. Ferreira, Peter Lemaire, Marina Scop Madeiros, Carolina Soares, Bruna Bellaver, Guilherme Bauer-Negrini, Firoza Z. Lussier, Guilherme Povala, João Pedro Ferrari-Souza, Sarah Abbas, Cristiano Schaffer Aguzzoli, Matheus Scarpatto Rodrigues, Francieli Rohden, Livia Amaral, Douglas Teixeira Leffa, Markley Oliveira, Dana Tudorascu, Cécile Tissot, Nesrine Rahmouni, Nicholas J. Ashton, Kaj Blennow, Chang Hyung Hong, Sang Joon Son, Pedro Rosa-Neto, Ann D. Cohen, Oscar L. Lopez, Victor L. Villemagne, Tharick A. Pascoal
Alzheimer's & Dementia - 2024 -
The relationship between dyadic perspective in subjective reports and objective cognitive decline in preclinical
Alzheimer's
David López-Martos, Anna Brugulat-Serrat, Alba Cañas-Martínez, Lidia Canals-Gispert, Paula Marne, Nina Gramunt, Marc Suárez-Calvet, Marta Milà-Alomà, Carolina Minguillon, Karine Fauria, Henrik Zetterberg, Kaj Blennow, Jose Luis Molinuevo, Juan Domingo Gispert, Oriol Grau-Rivera, Gonzalo Sánchez-Benavides
Alzheimer's & Dementia - 2024 -
Hippocampal degeneration is associated with GFAP levels in individuals with vascular dementia independently of
amyloidosis
Markley Oliveira, Bruna Bellaver, Firoza Z. Lussier, Pamela C.L. Ferreira, Guilherme Povala, Douglas Teixeira Leffa, Guilherme Bauer-Negrini, Matheus Scarpatto Rodrigues, Sarah Abbas, Hussein Zalzale, Francieli Rohden, Cynthia Felix, Carolina Soares, Pampa Saha, Emma Patrice Ruppert, Vitor Hugo Machado, Andreia Silva da Rocha, Dana Tudorascu, Andrea L Benedet, Nicholas J. Ashton, Cécile Tissot, Joseph Therriault, Stijn Servaes, Jenna Stevenson, Nesrine Rahmouni, Chang Hyung Hong, Hyun Woong Roh, Eduardo R. Zimmer, Kaj Blennow, Henrik Zetterberg, Thomas Karikari, Pedro Rosa-Neto, Sang Joon Son, Tharick A. Pascoal
Alzheimer's & Dementia - 2024 -
Proteome-wide analyses identifies plasma immune regulators of amyloid-beta
progression
Michael R. Duggan, Gabriela T. Gomez, Murat Bilgel, Jingsha Chen, Nicola Fattorelli, Timothy J. Hohman, Renzo Mancuso, Jenifer Cordon, Tonnar Castellano, Mary Ellen I. Koran, Julián Candia, Alexandria Lewis, Abhay Moghekar, Nicholas J. Ashton, Przemysław R Kac, Thomas Karikari, Kaj Blennow, Henrik Zetterberg, Anna Martinez-Muriana, Bart De Strooper, Madhav Thambisetty, Luigi Ferrucci, Rebecca F. Gottesman, Josef Coresh, Susan M. Resnick, Keenan A. Walker
Alzheimer's & Dementia - 2024 -
Sensitive methods to define subtle memory decline capture intra-individual hippocampal atrophy and increased cortical volumes in preclinical
Alzheimer’s
David López-Martos, Raffaele Cacciaglia, Marc Suárez-Calvet, Marta Milà-Alomà, Carolina Minguillon, Henrik Zetterberg, Kaj Blennow, Juan Domingo Gispert, Oriol Grau-Rivera, Gonzalo Sánchez-Benavides
Alzheimer's & Dementia - 2024 -
Evaluating Congruence Between Clinical and Biological Staging Across The Alzheimer’s Disease
Spectrum
Hussein Zalzale, Marina Scop Madeiros, Carolina Soares, Guilherme Bauer-Negrini, Guilherme Povala, Pamela C.L. Ferreira, Livia Amaral, Firoza Z. Lussier, Bruna Bellaver, Sarah Abbas, Matheus Scarpatto Rodrigues, Dana Tudorascu, Markley Oliveira, Cynthia Felix, Douglas Teixeira Leffa, Cécile Tissot, Cristiano Schaffer Aguzzoli, Emma Patrice Ruppert, Pampa Saha, Nesrine Rahmouni, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Belen Pascual, Brian A. Gordon, William J. Jagust, Val J. Lowe, Thomas Karikari, Hwamee Oh, William E. Klunk, David N. Soleimani-Meigooni, Pedro Rosa-Neto, Suzanne L. Baker, Tharick A. Pascoal
Alzheimer's & Dementia - 2024 -
Reduction of neurogranin protein correlates with increases of inflammasome proteins in post mortem cases of intermediate Alzheimer’s
disease
Regina T. Vontell, Ayled Barreda, Kaj Blennow, Henrik Zetterberg, Juan Pablo de Rivero Vaccari, Helen M. Bramlett, W. Dalton Dietrich, Robert W. Keane, David A. Davis, Tatjana Rundek, Xiaoyan Sun
Alzheimer's & Dementia - 2024 -
Glial and synaptic biomarkers as early indicators of mild cognitive
decline
Agnieszka Kulczynska-Przybik, Maciej Dulewicz, Henrik Zetterberg, Jörg Hanrieder, Kaj Blennow, Jan Mroczko, Daria Krawczuk, Julia Doroszkiewicz, Renata Borawska, Agnieszka Slowik, Barbara Mroczko
Alzheimer's & Dementia - 2024 -
A Nonlinear Relation between Body Mass Index and Long-Term Poststroke Functional Outcome-The Importance of Insulin Resistance, Inflammation, and Insulin-like Growth Factor-Binding
Protein-1.
Gustaf Gadd, Daniel Åberg, Alexander Wall, Henrik Zetterberg, Kaj Blennow, Katarina Jood, Christina Jern, Jörgen Isgaard, Johan Svensson, N David Åberg
International Journal of Molecular Sciences - 2024 -
Diagnosis of Alzheimer's disease using plasma biomarkers adjusted to clinical
probability.
Joseph Therriault, Shorena Janelidze, Andréa Lessa Benedet, Nicholas J. Ashton, Javier Arranz Martínez, Armand Gonzalez-Escalante, Bruna Bellaver, Daniel Alcolea, Agathe Vrillon, Helmet Karim, Michelle M Mielke, Chang Hyung Hong, Hyun Woong Roh, José Contador, Albert Puig Pijoan, Alicia Algeciras-Schimnich, Prashanthi Vemuri, Jonathan Graff-Radford, Val J Lowe, Thomas Karikari, Erin Jonaitis, Wagner Scheeren Brum, Cécile Tissot, Stijn Servaes, Nesrine Rahmouni, Arthur C Macedo, Jenna Stevenson, Jaime Fernandez-Arias, Yi-Ting Wang, Marcel S Woo, Manuel A Friese, Wan Lu Jia, Julien Dumurgier, Claire Hourregue, Emmanuel Cognat, Pamela Lukasewicz Ferreira, Paolo Vitali, Sterling Johnson, Tharick A Pascoal, Serge Gauthier, Alberto Lleó, Claire Paquet, Ronald C Petersen, David Salmon, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Erik Stomrud, Douglas Galasko, Sang Joon Son, Henrik Zetterberg, Juan Fortea, Marc Suárez-Calvet, Clifford R Jack, Kaj Blennow, Oskar Hansson, Pedro Rosa-Neto
Nature aging - 2024 -
Sex differences in the relationships between 24-h rest-activity patterns and plasma markers of Alzheimer’s disease
pathology
Maxime Van Egroo, Elise Beckers, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Heidi I.L. Jacobs
Alzheimer's Research and Therapy - 2024 -
Alzheimer Disease as a Clinical-Biological Construct-An International Working Group
Recommendation
Bruno Dubois, Nicolas Villain, Lon Schneider, Nick Fox, Noll Campbell, Douglas Galasko, Miia Kivipelto, Frank Jessen, Bernard Hanseeuw, Merce Boada, Frederik Barkhof, Agneta Nordberg, Lutz Froelich, Gunhild Waldemar, Kristian Steen Frederiksen, Alessandro Padovani, Vincent Planche, Christopher Rowe, Alexandre Bejanin, Agustin Ibanez, Stefano Cappa, Paulo Caramelli, Ricardo Nitrini, Ricardo Allegri, Andrea Slachevsky, Leonardo Cruz de Souza, Andrea Bozoki, Eric Widera, Kaj Blennow, Craig Ritchie, Marc Agronin, Francisco Lopera, Lisa Delano-Wood, Stephanie Bombois, Richard Levy, Madhav Thambisetty, Jean Georges, David T. Jones, Helen Lavretsky, Jonathan Schott, Jennifer Gatchel, Sandra Swantek, Paul Newhouse, Howard H. Feldman, Giovanni B. Frisoni
JAMA NEUROLOGY - 2024 -
Vascular risk burden is a key player in the early progression of Alzheimer's
disease
Joao Pedro Ferrari-Souza, Wagner Scheeren Brum, Lucas A. Hauschild, Lucas U. Da Ros, Pamela C. L. Ferreira, Bruna Bellaver, Douglas T. Leffa, Andrei Bieger, Cecile Tissot, Firoza Z. Lussier, Marco Antonio De Bastiani, Guilherme Povala, Andréa Lessa Benedet, Joseph Therriault, Yi-Ting Wang, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Sheila O. Martins, Diogo O. Souza, Pedro Rosa-Neto, Thomas Karikari, Tharick A. Pascoal, Eduardo R. Zimmer
NEUROBIOLOGY OF AGING - 2024 -
Functional connectivity changes in neurodegenerative biomarker-positive athletes with repeated
concussions
Indira Garcia-Cordero, Anna Vasilevskaya, Foad Taghdiri, Mozhgan Khodadadi, David Mikulis, Apameh Tarazi, Asma Mushtaque, Neda Anssari, Brenda Colella, Robin Green, Ekaterina Rogaeva, Christine Sato, Mark Grinberg, Danielle Moreno, Mohammed W. Hussain, Kaj Blennow, Henrik Zetterberg, Karen D. Davis, Richard Wennberg, Charles Tator, Maria C. Tartaglia
JOURNAL OF NEUROLOGY - 2024 -
Plasma concentrations of glial fibrillary acidic protein, neurofilament light, and tau in Alexander
disease
Nicholas J. Ashton, Guglielmo Di Molfetta, Kübra Tan, Kaj Blennow, Henrik Zetterberg, Albee Messing
Neurological Sciences - 2024 -
Strong diagnostic performance of plasma ptau217 for CSF biomarker-defined young-onset Alzheimer disease in a diagnostically heterogeneous clinical
cohort.
Dhamidhu Eratne, Qiao-Xin Li, Courtney Lewis, Christa Dang, Matthew J Y Kang, Jasleen Grewal, Samantha Loi, Mark Walterfang, Andrew H Evans, Charles B Malpas, Steve Pedrini, Ralph Martins, Pratishtha Chatterjee, Henrik Zetterberg, Kaj Blennow, Samuel F Berkovic, Alexander F Santillo, Steven Collins, Colin L Masters, Dennis Velakoulis
Journal of neurology - 2024 -
Cerebrospinal fluid synaptic biomarker changes in bipolar disorder - A longitudinal case-control
study.
Ulla Knorr, Anja Hviid Simonsen, Johanna Nilsson, Ann Brinkmalm-Westman, Henrik Zetterberg, Kaj Blennow, Mark Bech Knudsen, Julie Forman, Steen Gregers Hasselbalch, Lars Vedel Kessing
Journal of affective disorders - 2024 -
Association of serum glial fibrillary acidic protein with progression independent of relapse activity in multiple
sclerosis.
Igal Rosenstein, Anna Nordin, Hemin Sabir, Clas Malmeström, Kaj Blennow, Markus Axelsson, Lenka Novakova
Journal of neurology - 2024 -
Plasma phosphorylated tau181 outperforms [18F] fluorodeoxyglucose positron emission tomography in the identification of early Alzheimer
disease
Kely Monica Quispialaya, Joseph Therriault, Antonio Aliaga, Cecile Tissot, Stijn Servaes, Nesrine Rahmouni, Thomas Karikari, Andréa Lessa Benedet, Nicholas J. Ashton, Arthur C. Macedo, Firoza Z. Lussier, Jenna Stevenson, Yi-Ting Wang, Jaime Fernandez Arias, Ali Hosseini, Takashi Matsudaira, Bertrand Jean-Claude, Brian M. Gilfix, Eduardo R. Zimmer, Jean-Paul Soucy, Tharick A. Pascoal, Serge Gauthier, Henrik Zetterberg, Kaj Blennow, Pedro Rosa-Neto
EUROPEAN JOURNAL OF NEUROLOGY - 2024 -
Association of glial fibrillary acid protein, Alzheimer's disease pathology and cognitive
decline
Debora E. Peretti, Cecilia Boccalini, Federica Ribaldi, Max Scheffler, Moira Marizzoni, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Giovanni B. Frisoni, Valentina Garibotto
BRAIN - 2024 -
Cerebrospinal fluid p-tau181, 217, and 231 in definite Creutzfeldt-Jakob disease with and without concomitant
pathologies
Andreja Emersic, Nicholas J. Ashton, Agathe Vrillon, Juan Lantero Rodriguez, Jernej Mlakar, Milica Gregoric Kramberger, Fernando Gonzalez-Ortiz, Przemyslaw R. Kac, Maciej Dulewicz, Jörg Hanrieder, Eugeen Vanmechelen, Uros Rot, Henrik Zetterberg, Thomas Karikari, Sasa Cucnik, Kaj Blennow
ALZHEIMERS & DEMENTIA - 2024 -
Tau protein profiling in tauopathies: a human brain
study
Juan Lantero Rodriguez, Elena Camporesi, Laia Montoliu-Gaya, Johan Gobom, Diana Piotrowska, Maria Olsson, Irena Matečko-Burmann, Bruno Becker, Ann Brinkmalm, Björn Marcus Burmann, Michael Perkinton, Nicholas J. Ashton, Nick C. Fox, Tammaryn Lashley, Henrik Zetterberg, Kaj Blennow, Gunnar Brinkmalm
MOLECULAR NEURODEGENERATION - 2024 -
Circulating levels of neurofilament light chain as a biomarker of infarct and white matter hyperintensity volumes after ischemic
stroke.
Lukas Holmegaard, Christer Jensen, Annie Pedersen, Christian Blomstrand, Kaj Blennow, Henrik Zetterberg, Katarina Jood, Christina Jern
Scientific reports - 2024 -
Data-driven CSF biomarker profiling: imaging and clinical outcomes in a cohort at risk of Alzheimer's
disease.
Georgette Argiris, Muge Akinci, Cleofé Peña-Gómez, Eleni Palpatzis, Marina Garcia-Prat, Mahnaz Shekari, Kaj Blennow, Henrik Zetterberg, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Nicholas J. Ashton, Thomas Karikari, Ann Brinkmalm-Westman, Juan Lantero Rodriguez, Karine Fauria, Gonzalo Sánchez-Benavides, Oriol Grau-Rivera, Marc Suárez-Calvet, Eider M Arenaza-Urquijo, For The Alfa Study
Alzheimer's research & therapy - 2024 -
Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and human proteomic
studies.
Aurore Delvenne, Charysse Vandendriessche, Johan Gobom, Marlies Burgelman, Pieter Dujardin, Clint De Nolf, Betty M Tijms, Charlotte E Teunissen, Suzanne E Schindler, Frans Verhey, Inez Ramakers, Pablo Martinez-Lage, Mikel Tainta, Rik Vandenberghe, Jolien Schaeverbeke, Sebastiaan Engelborghs, Ellen De Roeck, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Yvonne Freund-Levi, Simon Lovestone, Johannes Streffer, Lars Bertram, Kaj Blennow, Henrik Zetterberg, Pieter Jelle Visser, Roosmarijn E Vandenbroucke, Stephanie J B Vos
Fluids and barriers of the CNS - 2024 -
Hormone therapy is associated with lower Alzheimer's disease tau biomarkers in post-menopausal females -evidence from two independent
cohorts.
Yi-Ting Wang, Joseph Therriault, Cécile Tissot, Stijn Servaes, Nesrine Rahmouni, Arthur Cassa Macedo, Jaime Fernandez-Arias, Sulantha S Mathotaarachchi, Jenna Stevenson, Firoza Z Lussier, Andréa Lessa Benedet, Tharick A Pascoal, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Serge Gauthier, Pedro Rosa-Neto
Alzheimer's research & therapy - 2024 -
Tyro3 and Gas6 are associated with white matter and myelin integrity in multiple
sclerosis.
Igal Rosenstein, Lenka Nováková Nyrén, Hlin Kvartsberg, Anna Nordin, Sofia Rasch, Elzbieta Rembeza, Sofia Sandgren, Clas Malmeström, Stefanie Fruhwürth, Markus Axelsson, Kaj Blennow, Henrik Zetterberg, Jan Lycke
Journal of Neuroinflammation - 2024 -
Association of preoperative to postoperative change in cerebrospinal fluid fibrinogen with postoperative
delirium.
Thomas Payne, Jennifer Taylor, David Kunkel, Katherine Konieczka, Frankie Ingram, Kaj Blennow, Henrik Zetterberg, Robert A Pearce, Anke Meyer-Franke, Niccolò Terrando, Katerina Akassoglou, Robert D Sanders, Richard C Lennertz
BJA open - 2024 -
Cognitive status and demographics modify the association between subjective cognition and
amyloid.
Corey J Bolton, Omair A Khan, Dandan Liu, Sydney Wilhoite, Logan Dumitrescu, Amalia Peterson, Kaj Blennow, Henrik Zetterberg, Timothy J Hohman, Angela L Jefferson, Katherine A Gifford
Annals of clinical and translational neurology - 2024 -
CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy
70-year-olds.
Sofia Bergström, Sára Mravinacová, Olof Lindberg, Anna Zettergren, Eric Westman, Lars-Olof Wahlund, Kaj Blennow, Henrik Zetterberg, Silke Kern, Ingmar Skoog, Anna Månberg
Clinical proteomics - 2024 -
Corticotropin-releasing hormone as a candidate biomarker for parkinsonian
disorders
Bárbara Fernandes Gomes, Atul Kumar, Nicholas J. Ashton, Sara Hall, Erik Stomrud, Ruben Smith, Henrik Zetterberg, Kaj Blennow, Niklas Mattsson-Carlgren, Oskar Hansson
BRAIN COMMUNICATIONS - 2024 -
NeuroToolKit Data Hackathon: advancing data collaboration in Alzheimer's
disease
Craig Ritchie, Kaj Blennow, Juan Domingo Gispert, Sterling Johnson, Ingrid van Maurik, Lisa Vermunt, Marc Suárez-Calvet, Caitlin P. McHugh, Matthew H.S. Clement, Alexandra Anastasiu, Eugen Rosenfeld, Oana Cosma, Chad A. Logan, Frances Catherine Quevenco, Mariana Castro Dias, Margherita Carboni
Frontiers in Neuroscience - 2024 -
Chemical signatures delineate heterogeneous amyloid plaque populations across the Alzheimer's disease
spectrum.
Srinivas Koutarapu, Junyue Ge, Maciej Dulewicz, Meera Srikrishna, Alicja Szadziewska, Jack Wood, Kaj Blennow, Henrik Zetterberg, Wojciech Michno, Natalie S Ryan, Tammaryn Lashley, Jeffrey Savas, Michael Schöll, Jörg Hanrieder
bioRxiv : the preprint server for biology - 2024 -
Glial reactivity is linked to synaptic dysfunction across the aging and Alzheimer's disease
spectrum.
Tharick Pascoal, Francieli Rohden, Pamela Ferreira, Bruna Bellaver, João Pedro Ferrari-Souza, Cristiano Aguzzoli, Carolina Soares, Sarah Abbas, Hussein Zalzale, Guilherme Povala, Firoza Lussier, Douglas Leffa, Guilherme Bauer-Negrini, Nesrine Rahmouni, Cécile Tissot, Joseph Therriault Therriault, Stijn Servaes, Jenna Stevenson, Andrea L Benedet, Nicholas J. Ashton, Thomas Karikari, Dana Tudorascu, Henrik Zetterberg, Kaj Blennow, Eduardo Zimmer, Diogo Souza, Pedro Rosa-Neto
Research square - 2024 -
Plasma p-tau212 as a biomarker of sporadic and Down Syndrome Alzheimer's
disease.
Przemysław R Kac, Daniel Alcolea, Laia Montoliu-Gaya, Susana Fernández, Juan Lantero Rodriguez, Lucía Maure, Fernando Gonzalez-Ortiz, Bessy Benejam, Michael Turton, Isabel Barroeta, Peter Harrison, Laura Videla, Nicholas J. Ashton, Alberto Lleó, Henrik Zetterberg, María Carmona-Iragui, Thomas Karikari, Juan Fortea, Kaj Blennow
medRxiv : the preprint server for health sciences - 2024 -
Synaptic protein CSF levels relate to memory scores in individuals without
dementia.
Kirsten E J Wesenhagen, Diederick M de Leeuw, Jori Tomassen, Johan Gobom, Isabelle Bos, Stephanie J B Vos, Pablo Martinez-Lage, Mikel Tainta, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Rik Vandenberghe, Yvonne Freund-Levi, Frans Verhey, Simon Lovestone, Johannes Streffer, Valerija Dobricic, Kaj Blennow, Philip Scheltens, August B Smit, Lars Bertram, Charlotte E Teunissen, Henrik Zetterberg, Betty M Tijms
Research square - 2024 -
The CentiMarker Project: Standardizing Quantitative Alzheimer's disease Fluid Biomarkers for Biologic
Interpretation.
Guoqiao Wang, Yan Li, Chengjie Xiong, Yuchen Cao, Suzanne E Schindler, Eric McDade, Kaj Blennow, Oskar Hansson, Jeffrey L Dage, Clifford R Jack, Charlotte E Teunissen, Leslie M Shaw, Henrik Zetterberg, Ibanez Laura, Jigyasha Timsina, Cruchaga Carlos, Randall J Bateman
medRxiv : the preprint server for health sciences - 2024 -
Gut Microbiome Compositional and Functional Features Associate with Alzheimer's Disease
Pathology.
Jea Woo Kang, Lora A Khatib, Margo B Heston, Amanda H Dilmore, Jennifer S Labus, Yuetiva Deming, Leyla Schimmel, Colette Blach, Daniel McDonald, Antonio Gonzalez, MacKenzie Bryant, Karenina Sanders, Ara Schwartz, Tyler K Ulland, Sterling C Johnson, Sanjay Asthana, Cynthia M Carlsson, Nathaniel A Chin, Kaj Blennow, Henrik Zetterberg, Federico E Rey, Rima Kaddurah-Daouk, Rob Knight, Barbara B Bendlin
medRxiv : the preprint server for health sciences - 2024 -
A machine learning-based prediction of tau load and distribution in Alzheimer's disease using plasma, MRI and clinical
variables.
Linda Karlsson, Jacob Vogel, Ida Arvidsson, Kalle Åström, Olof Strandberg, Jakob Seidlitz, Richard A I Bethlehem, Erik Stomrud, Rik Ossenkoppele, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Sebastian Palmqvist, Ruben Smith, Shorena Janelidze, Renaud La Joie, Gil D Rabinovici, Alexa Pichet Binette, Niklas Mattsson-Carlgren, Oskar Hansson
medRxiv : the preprint server for health sciences - 2024 -
Elevated plasma p-tau231 is associated with reduced generalization and medial temporal lobe dynamic network flexibility among healthy older African
Americans
Miray Budak, Bernadette A. Fausto, Zuzanna Osiecka, Mustafa Sheikh, Robert Perna, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Patricia Fitzgerald-Bocarsly, Mark A. Gluck
ALZHEIMERS RESEARCH & THERAPY - 2024 -
Plasma phosphorylated-tau217 is increased in Niemann-Pick disease type
C
Fernando Gonzalez-Ortiz, Thomas Karikari, Danielle Taylor-Te Vruchte, Dawn Shepherd, Bjorn-Eivind Kirsebom, Tormod Fladby, Frances Platt, Kaj Blennow
BRAIN COMMUNICATIONS - 2024 -
Lumipulse-Measured Cerebrospinal Fluid Biomarkers for the Early Detection of Alzheimer
Disease
Michelle Safransky, Jenna R. Groh, Kaj Blennow, Henrik Zetterberg, Yorghos Tripodis, Brett Martin, Jason Weller, Breton M. Asken, Gil D. Rabinovici, Wendy Wei Qiao Qiu, Ann C. Mckee, Thor D. Stein, Jesse Mez, Rachel L. Henson, Justin Long, John C. Morris, Richard J. Perrin, Suzanne E. Schindler, Michael L. Alosco
NEUROLOGY - 2024 -
Circulating medium- and long-chain acylcarnitines are associated with plasma P-tau181 in cognitively normal older
adults
Tahmida Sharmin, Pratishtha Chatterjee, James D. Doecke, Nicholas J. Ashton, Kevin Huynh, Steve Pedrini, Hamid R. Sohrabi, Benjamin Heng, Shaun Eslick, Henrik Zetterberg, Kaj Blennow, Manohar Garg, Ralph N. Martins
JOURNAL OF NEUROCHEMISTRY - 2024 -
Identification of late-stage tau accumulation using plasma
phospho-tau217
Marcel S. Woo, Joseph Therriault, Erin M. Jonaitis, Rachael Wilson, Rebecca E. Langhough, Nesrine Rahmouni, Andréa Lessa Benedet, Nicholas J. Ashton, Cecile Tissot, Juan Lantero Rodriguez, Arthur C. Macedo, Stijn Servaes, Yi-Ting Wang, Jaime Fernandez Arias, Seyyed Ali Hosseini, Tobey J. Betthauser, Firoza Z. Lussier, Robert Hopewell, Gallen Triana-Baltzer, Hartmuth C. Kolb, Andreas Jeromin, Eliane Kobayashi, Gassan Massarweh, Manuel A. Friese, Jesse Klostranec, Paolo Vilali, Tharick A. Pascoal, Serge Gauthier, Henrik Zetterberg, Kaj Blennow, Sterling C. Johnson, Pedro Rosa-Neto
EBIOMEDICINE - 2024 -
Plasma neurofilament light chain as prognostic marker of cognitive decline in neurodegenerative diseases, a clinical setting
study
Karl Gotze, Agathe Vrillon, Julien Dumurgier, Sandrine Indart, Marta Sanchez-Ortiz, Hela Slimi, Agathe Raynaud-Simon, Emmanuel Cognat, Matthieu Martinet, Henrik Zetterberg, Kaj Blennow, Claire Hourregue, Elodie Bouaziz-Amar, Claire Paquet, Matthieu Lilamand
ALZHEIMERS RESEARCH & THERAPY - 2024 -
Plasma and CSF neurofilament light chain distinguish neurodegenerative from primary psychiatric conditions in a clinical
setting
Dhamidhu Eratne, Matthew J. Y. Kang, Courtney Lewis, Christa Dang, Charles B. Malpas, Michael Keem, Jasleen Grewal, Vladimir Marinov, Amy Coe, Cath Kaylor-Hughes, Thomas Borchard, Chhoa Keng-Hong, Alexandra Waxmann, Burcu Saglam, Tomas Kalincik, Richard Kanaan, Wendy Kelso, Andrew Evans, Sarah Farrand, Samantha Loi, Mark Walterfang, Christiane Stehmann, Qiao-Xin Li, Steven Collins, Colin L. Masters, Alexander F. Santillo, Henrik Zetterberg, Kaj Blennow, Samuel F. Berkovic, Dennis Velakoulis
ALZHEIMERS & DEMENTIA - 2024 -
Examination of plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in former elite American football
players
Annalise E. Miner, Jenna R. Groh, Yorghos Tripodis, Charles H. Adler, Laura J. Balcer, Charles Bernick, Henrik Zetterberg, Kaj Blennow, Elaine Peskind, Nicholas J. Ashton, Charles E. Gaudet, Brett Martin, Joseph N. Palmisano, Sarah J. Banks, William B. Barr, Jennifer V. Wethe, Robert C. Cantu, David W. Dodick, Douglas I. Katz, Jesse Mez, Suzan van Amerongen, Jeffrey L. Cummings, Martha E. Shenton, Eric M. Reiman, Robert A. Stern, Michael L. Alosco
ALZHEIMERS & DEMENTIA - 2024 -
Association of Vascular Risk Factors and Cerebrovascular Pathology With Alzheimer Disease Pathologic Changes in Individuals Without
Dementia
Luigi Lorenzini, Alessio Maranzano, Silvia Ingala, Lyduine E. Collij, Mario Tranfa, Kaj Blennow, Carol Di Perri, Christopher Foley, Nick C. Fox, Giovanni B. Frisoni, Sven Haller, Pablo Martinez-Lage, Daisy Mollison, John O'Brien, Pierre Payoux, Craig Ritchie, Philip Scheltens, Adam J. Schwarz, Carole H. Sudre, Betty M. Tijms, Federico Verde, Nicola Ticozzi, Vincenzo Silani, Pieter Jelle Visser, Adam Waldman, Robin Wolz, Gael Chetelat, Michael Ewers, Alle Meije Wink, Henk Mutsaerts, Juan Domingo Gispert, Joanna M. Wardlaw, Frederik Barkhof
NEUROLOGY - 2024 -
Changes in cerebrospinal fluid proteins across the spectrum of untreated and treated chronic HIV-1
infection
Zicheng Hu, Paola Cinque, Ameet Dravid, Lars Hagberg, Aylin Yilmaz, Henrik Zetterberg, Dietmar Fuchs, Johanna Gostner, Kaj Blennow, Serena S. Spudich, Laura Kincer, Shuntai Zhou, Sarah Beth Joseph, Ronald Swanstrom, Richard W. Price, Magnus Gisslén
PLOS PATHOGENS - 2024 -
Gene-variant specific effects of plasma amyloid-β levels in Swedish autosomal dominant Alzheimer
disease
Charlotte Johansson, Steinunn Thordardottir, Jose Laffita-Mesa, Josef Pannee, Elena Rodriguez-Vieitez, Henrik Zetterberg, Kaj Blennow, Caroline Graff
ALZHEIMERS RESEARCH & THERAPY - 2024 -
Neurofilament light chain associates with IVH and ROP in extremely preterm
infants
Ulrika Sjöbom, Annika Öhrfelt, Aldina Pivodic, Anders K. Nilsson, Kaj Blennow, Henrik Zetterberg, William Hellström, Hanna Danielsson, Lotta Granse, Karin Sävman, Dirk Wackernagel, Ingrid Hansen-Pupp, David Ley, Ann Hellström, Chatarina Löfqvist
PEDIATRIC RESEARCH - 2024 -
REAL AD-Validation of a realistic screening approach for early Alzheimer's
disease
Antoine Leuzy, Fiona Heeman, Iris Bosch, Frida Lenér, Maria Dottori, Kajsa Quitz, Alexis Moscoso Rial, Silke Kern, Henrik Zetterberg, Kaj Blennow, Michael Schöll
ALZHEIMERS & DEMENTIA - 2024 -
Influence of Different Diagnostic Criteria on Alzheimer Disease Clinical
Research
Andrei Bieger, Wagner Scheeren Brum, Wyllians V. Borelli, Joseph Therriault, Marco A. De Bastiani, Amanda G. Moreira, Andréa Lessa Benedet, Joao Pedro Ferrari-Souza, Jaderson C. Da Costa, Diogo O. Souza, Raphael M. Castilhos, Artur Francisco Schumacher Schuh, Marcia L. Fagundes Chaves, Michael Schöll, Henrik Zetterberg, Kaj Blennow, Tharick A. Pascoal, Serge Gauthier, Pedro Rosa-Neto, Lucas P. Schilling, Eduardo R. Zimmer
NEUROLOGY - 2024 -
Plasma NfL, GFAP, amyloid, and p-tau species as Prognostic biomarkers in Parkinson's
disease
Andrea Pilotto, Nicholas J. Ashton, Alessandro Lupini, Beatrice Battaglio, Cinzia Zatti, Chiara Trasciatti, Stefano Gipponi, Elisabetta Cottini, Ilaria Grossi, Alessandro Salvi, Giuseppina de Petro, Marina Pizzi, Antonio Canale, Kaj Blennow, Henrik Zetterberg, Alessandro Padovani
JOURNAL OF NEUROLOGY - 2024 -
Neuroinflammation, cerebrovascular dysfunction and diurnal cortisol biomarkers in a memory clinic cohort: Findings from the Co-STAR
study
Makrina Daniilidou, Jasper Holleman, Goran Hagman, Ingemar Kareholt, Malin Aspo, Ann Brinkmalm, Henrik Zetterberg, Kaj Blennow, Alina Solomon, Miia Kivipelto, Shireen Sindi, Anna Matton
TRANSLATIONAL PSYCHIATRY - 2024 -
CSF neurogranin levels as a biomarker in Alzheimer's disease and frontotemporal lobar degeneration: a cross-sectional
analysis
Vanesa Jurasova, Ross Andel, Alzbeta Katonova, Katerina Veverova, Terezie Zuntychova, Hana Horakova, Martin Vyhnalek, Tereza Kolarova, Vaclav Matoska, Kaj Blennow, Jakub Hort
ALZHEIMERS RESEARCH & THERAPY - 2024 -
Plasma p-tau181 and amyloid markers in Alzheimer's disease: A comparison between Lumipulse and
SIMOA
Virginia Quaresima, Andrea Pilotto, Chiara Trasciatti, Chiara Tolassi, Marta Parigi, Diego Bertoli, Cristina Mordenti, Alice Galli, Andrea Rizzardi, Salvatore Caratozzolo, Alberto Benussi, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Silvia Giliani, Duilio Brugnoni, Alessandro Padovani
NEUROBIOLOGY OF AGING - 2024 -
CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer's
disease
Aurore Delvenne, Johan Gobom, Suzanne E. Schindler, Mara ten Kate, Lianne M. Reus, Valerija Dobricic, Betty M. Tijms, Tammie L. S. Benzinger, Carlos Cruchaga, Charlotte E. Teunissen, Inez Ramakers, Pablo Martinez-Lage, Mikel Tainta, Rik Vandenberghe, Jolien Schaeverbeke, Sebastiaan Engelborghs, Ellen De Roeck, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Yvonne Freund-Levi, Simon Lovestone, Johannes Streffer, Frederik Barkhof, Lars Bertram, Kaj Blennow, Henrik Zetterberg, Pieter Jelle Visser, Stephanie J. B. Vos
ALZHEIMERS & DEMENTIA - 2024 -
Alzheimer's Disease Biomarker Analysis Using Targeted Mass
Spectrometry.
Johan Gobom, Ann Brinkmalm-Westman, Gunnar Brinkmalm, Kaj Blennow, Henrik Zetterberg
Molecular & cellular proteomics : MCP - 2024 -
Blood biomarkers of neurodegeneration associate differently with amyloid deposition, medial temporal atrophy, and cerebrovascular changes in APOE ε4-enriched cognitively unimpaired
elderly
Mikko Koivumäki, Laura Ekblad, Juan Lantero Rodriguez, Nicholas J. Ashton, Thomas Karikari, Semi Helin, Riitta Parkkola, Jyrki Lötjönen, Henrik Zetterberg, Kaj Blennow, Juha O. Rinne, Anniina Snellman
Alzheimer's Research and Therapy - 2024 -
The neutrophil to lymphocyte ratio associates with markers of Alzheimer’s disease pathology in cognitively unimpaired elderly
people
Tovia Jacobs, Sean R. Jacobson, Juan Fortea, Jeffrey S. Berger, Alok Vedvyas, Karyn Marsh, Tianshe He, Eugenio Gutierrez-Jimenez, Nathanael R. Fillmore, Moses Gonzalez, Luisa Figueredo, Naomi L. Gaggi, Chelsea Reichert Plaska, Nunzio Pomara, Esther Blessing, Rebecca Betensky, Henry Rusinek, Henrik Zetterberg, Kaj Blennow, Lidia Glodzik, Thomas M. Wisniweski, Mony J. de Leon, Ricardo S. Osorio, Jaime Ramos-Cejudo
Immunity and Ageing - 2024 -
Serial Cerebrospinal Fluid Sampling Reveals Trajectories of Potential Synaptic Biomarkers in Early Stages of Alzheimer's
Disease
Flora H. Duits, Johanna Nilsson, Henrik Zetterberg, Kaj Blennow, Wiesje M. van der Flier, Charlotte E. Teunissen, Ann Brinkmalm
JOURNAL OF ALZHEIMERS DISEASE - 2024 -
A prospective feasibility trial exploring novel biomarkers for neurotoxicity after isolated limb
perfusion
Anna Corderfeldt, Markus Axelsson, G. Bragadottir, Kaj Blennow, Henrik Zetterberg, Roger Olofsson Bagge
Perfusion - 2024 -
Acute-Phase Neurofilament Light and Glial Fibrillary Acidic Proteins in Cerebrospinal Fluid Predict Long-Term Outcome After Severe Traumatic Brain
Injury
Emma Andersson, Martin Öst, Keti Dalla, Henrik Zetterberg, Kaj Blennow, Bengt Nellgård
NEUROCRITICAL CARE - 2024 -
High levels of neurofilament light and YKL-40 in cerebrospinal fluid are related to poor outcome in
ALS
Christoffer Rosén, Bernardo Mitre, Bengt Nellgård, Markus Axelsson, Radu Constantinescu, Peter Munch Andersen, Keti Dalla, Kaj Blennow, Gustav Nilsson, Henrik Zetterberg, Hans Rosén
JOURNAL OF THE NEUROLOGICAL SCIENCES - 2024 -
Standard versus High Cardiopulmonary Bypass Flow Rate: A Randomized Controlled Subtrial Comparing Brain Injury Biomarker
Release
Anna Corderfeldt Keiller, Markus Axelsson, Gudrun Bragadottir, Lukas Lannemyr, Johanna Wijk, Kaj Blennow, Henrik Zetterberg, Roger Olofsson Bagge
Journal of Cardiothoracic and Vascular Anesthesia - 2024 -
APPETITE HORMONES AND CYTOKINES IN YOUNG GIRLS AT HIGH RISK OF DEVELOPING ANOREXIA
NERVOSA
Elisabet Wentz, Karin Dahlin, Kajsa Järvholm, Annika Lekman, Hayder Schweliyya, Kaj Blennow, Henrik Zetterberg, Erik Schéle, Suzanne L. Dickson, Jovanna Dahlgren
Oral presentation at Eating Disorders Reseach Society conference, Sitges, Spain - 2024 -
Comparison of plasma and neuroimaging biomarkers to predict cognitive decline in non-demented memory clinic
patients
Augusto J. Mendes, Federica Ribaldi, Aurelien Lathuiliere, Nicholas J. Ashton, Henrik Zetterberg, Marc Abramowicz, Max Scheffler, Frédéric Assal, Valentina Garibotto, Kaj Blennow, Giovanni B. Frisoni
Alzheimer's Research and Therapy - 2024 -
CSF β-Amyloid and Tau Biomarker Changes in Veterans With Mild Traumatic Brain
Injury.
Ge Li, Jeffrey Iliff, Jane Shofer, Cynthia L Mayer, James Meabon, David Cook, Kathleen F Pagulayan, Murray A Raskind, Henrik Zetterberg, Kaj Blennow, Elaine R Peskind
Neurology - 2024 -
Association of Vascular Risk Factors and CSF and Imaging Biomarkers With White Matter Hyperintensities in Former American Football
Players.
Monica T Ly, Fatima Tuz-Zahra, Yorghos Tripodis, Charles H Adler, Laura J Balcer, Charles Bernick, Henrik Zetterberg, Kaj Blennow, Elaine R Peskind, Rhoda Au, Sarah J Banks, William B Barr, Jennifer V Wethe, Mark W Bondi, Lisa M Delano-Wood, Robert C Cantu, Michael J Coleman, David W Dodick, Michael D McClean, Jesse B Mez, Joseph Palmisano, Brett Martin, Kaitlin Hartlage, Alexander P Lin, Inga K Koerte, Jeffrey L Cummings, Eric M Reiman, Martha E Shenton, Robert A Stern, Sylvain Bouix, Michael L Alosco
Neurology - 2024 -
Neurological involvement among non-hospitalized adolescents and young adults 6 months after acute
COVID-19
Lise Beier Havdal, Joel Selvakumar, Lise Lund Berven, Tonje Stiansen-Sonerud, Henrik Zetterberg, Kaj Blennow, Trygve Holmøy, Vegard Bruun Bratholm Wyller
Frontiers in Neurology - 2024 -
Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer's disease in the EMIF-AD
study
Rebecca G. Smith, Ehsan Pishva, Morteza Kouhsar, Jennifer Imm, Valerija Dobricic, Peter Johannsen, Michael Wittig, Andre Franke, Rik Vandenberghe, Jolien Schaeverbeke, Yvonne Freund-Levi, Lutz Froelich, Philip Scheltens, Charlotte E. Teunissen, Giovanni Frisoni, Olivier Blin, Jill C. Richardson, Regis Bordet, Sebastiaan Engelborghs, Ellen de Roeck, Pablo Martinez-Lage, Miren Altuna, Mikel Tainta, Alberto Lleo, Isabel Sala, Julius Popp, Gwendoline Peyratout, Laura Winchester, Alejo Nevado-Holgado, Frans Verhey, Magda Tsolaki, Ulf Andreasson, Kaj Blennow, Henrik Zetterberg, Johannes Streffer, Stephanie J. B. Vos, Simon Lovestone, Pieter Jelle Visser, Lars Bertram, Katie Lunnon
ALZHEIMERS & DEMENTIA - 2024 -
Blood-based multivariate methylation risk score for cognitive impairment and
dementia
Jarno Koetsier, Rachel Cavill, Rick Reijnders, Joshua Harvey, Jan Homann, Morteza Kouhsar, Kay Deckers, Sebastian Kohler, Lars M. T. Eijssen, Daniel L. A. van den Hove, Ilja Demuth, Sandra Duezel, Rebecca G. Smith, Adam R. Smith, Joe Burrage, Emma M. Walker, Gemma Shireby, Eilis Hannon, Emma Dempster, Tim Frayling, Jonathan Mill, Valerija Dobricic, Peter Johannsen, Michael Wittig, Andre Franke, Rik Vandenberghe, Jolien Schaeverbeke, Yvonne Freund-Levi, Lutz Froelich, Philip Scheltens, Charlotte E. Teunissen, Giovanni Frisoni, Olivier Blin, Jill C. Richardson, Regis Bordet, Sebastiaan Engelborghs, Ellen de Roeck, Pablo Martinez-Lage, Mikel Tainta, Alberto Lleo, Isabel Sala, Julius Popp, Gwendoline Peyratout, Frans Verhey, Magda Tsolaki, Ulf Andreasson, Kaj Blennow, Henrik Zetterberg, Johannes Streffer, Stephanie J. B. Vos, Simon Lovestone, Pieter-Jelle Visser, Christina M. Lill, Lars Bertram, Katie Lunnon, Ehsan Pishva
ALZHEIMERS & DEMENTIA - 2024 -
Serum neurofilament light at diagnosis: a prognostic indicator for accelerated disease progression in Parkinson's
Disease
Camilla Christina Pedersen, Anastasia Ushakova, Guido Alves, Ole-Bjorn Tysnes, Kaj Blennow, Henrik Zetterberg, Jodi Maple-Grodem, Johannes Lange
NPJ PARKINSONS DISEASE - 2024 -
CT1812 biomarker signature from a meta-analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer's
disease
Britney N. Lizama, Claire Williams, Hilary A. North, Kiran Pandey, Duc Duong, Valentina Di Caro, Adam P. Mecca, Kaj Blennow, Henrik Zetterberg, Allan I. Levey, Michael Grundman, Christopher H. van Dyck, Anthony O. Caggiano, Nicholas T. Seyfried, Mary E. Hamby
ALZHEIMERS & DEMENTIA - 2024 -
Biomarkers of tau phosphorylation state are associated with the clinical course of multiple
sclerosis
Andreja Emersic, Thomas Karikari, Przemyslaw R. Kac, Fernando Gonzalez-Ortiz, Maciej Dulewicz, Nicholas J. Ashton, Gregor Brecl Jakob, Alenka Horvat Ledinek, Jörg Hanrieder, Henrik Zetterberg, Uros Rot, Sasa Cucnik, Kaj Blennow
MULTIPLE SCLEROSIS AND RELATED DISORDERS - 2024 -
Prognostic value of Alzheimer's ' s disease plasma biomarkers in the oldest-old: a prospective primary care-based
study
Pamela Martino-Adami, Madhurima Chatterjee, Luca Kleineidam, Siegfried Weyerer, Horst Bickel, Birgitt Wiese, Steffi G. Riedel-Heller, Martin Scherer, Kaj Blennow, Henrik Zetterberg, Michael Wagner, Anja Schneider, Alfredo Ramirez
LANCET REGIONAL HEALTH-EUROPE - 2024 -
Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary
Care
Sebastian Palmqvist, Pontus Tideman, Niklas Mattsson-Carlgren, Suzanne E. Schindler, Ruben Smith, Rik Ossenkoppele, Susanna Calling, Tim West, Mark Monane, Philip B. Verghese, Joel B. Braunstein, Kaj Blennow, Shorena Janelidze, Erik Stomrud, Gemma Salvado, Oskar Hansson
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION - 2024 -
Plasma Phosphorylated Tau 217 and Aβ42/40 to Predict Early Brain Aβ Accumulation in People Without Cognitive
Impairment
Shorena Janelidze, Nicolas R. Barthelemy, Gemma Salvado, Suzanne E. Schindler, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Joel B. Braunstein, Vitaliy Ovod, James G. Bollinger, Yingxin He, Yan Li, Cyrus A. Raji, John C. Morris, David M. Holtzman, Nicholas J. Ashton, Kaj Blennow, Erik Stomrud, Randall J. Bateman, Oskar Hansson
JAMA NEUROLOGY - 2024 -
Osteopontin: A novel marker of pre-symptomatic sporadic Alzheimer's
disease
Marc James Quesnel, Anne Labonte, Cynthia Picard, Daniel C. Bowie, Henrik Zetterberg, Kaj Blennow, Ann Brinkmalm, Sylvia Villeneuve, Judes Poirier
ALZHEIMERS & DEMENTIA - 2024 -
Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non-demented
individuals
Luigi Lorenzini, Lyduine E. Collij, Niccolo Tesi, Natalia Vilor-Tejedor, Silvia Ingala, Kaj Blennow, Christopher Foley, Giovanni B. Frisoni, Sven Haller, Henne Holstege, Sven van der van der Lee, Pablo Martinez-Lage, Riccardo E. Marioni, Daniel L. McCartney, John O' Brien, Tiago Gil Oliveira, Pierre Payoux, Marcel Reinders, Craig Ritchie, Philip Scheltens, Adam J. Schwarz, Carole H. Sudre, Adam D. Waldman, Robin Wolz, Gael Chatelat, Michael Ewers, Alle Meije Wink, Henk J. M. M. Mutsaerts, Juan Domingo Gispert, Pieter Jelle Visser, Betty M. Tijms, Andre Altmann, Frederik Barkhof
ALZHEIMERS & DEMENTIA - 2024 -
Associations between Microglia and Astrocytic Proteins and Tau Biomarkers across the Continuum of Alzheimer's
Disease
Julia Doroszkiewicz, Agnieszka Kulczynska-Przybik, Maciej Dulewicz, Jan Mroczko, Renata Borawska, Agnieszka Slowik, Henrik Zetterberg, Jörg Hanrieder, Kaj Blennow, Barbara Mroczko
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2024 -
18F-Flortaucipir (AV1451) imaging identifies grey matter atrophy in retired
athletes
Anna Vasilevskaya, Chloe Anastassiadis, Simrika Thapa, Foad Taghdiri, Mozhgan Khodadadi, Namita Multani, Pablo Rusjan, Miracle Ozzoude, Apameh Tarazi, Asma Mushtaque, Richard Wennberg, Sylvain Houle, Robin Green, Brenda Colella, Neil Vasdev, Kaj Blennow, Henrik Zetterberg, Thomas Karikari, Christine Sato, Danielle Moreno, Ekaterina Rogaeva, David Mikulis, Karen Deborah Davis, Charles Tator, Maria Carmela Tartaglia
JOURNAL OF NEUROLOGY - 2024 -
The Taxonomy of Subjective Cognitive Decline: Proposal and First Clinical Evidence from the Geneva Memory Clinic
Cohort
Federica Ribaldi, Rafael Palomo, Daniele Altomare, Max Scheffler, Frederic Assal, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Marc Abramowicz, Valentina Garibotto, Christian Chicherio, Giovanni B. Frisoni
NEURODEGENERATIVE DISEASES - 2024 -
Amyloid-β peptide signature associated with cerebral amyloid angiopathy in familial Alzheimer's disease with APPdup and Down
syndrome
Amal Kasri, Elena Camporesi, Eleni Gkanatsiou, Susana Boluda, Gunnar Brinkmalm, Lev Stimmer, Junyue Ge, Jörg Hanrieder, Nicolas Villain, Charles Duyckaerts, Yannick Vermeiren, Sarah E. Pape, Gael Nicolas, Annie Laquerriere, Peter Paul De Deyn, David Wallon, Kaj Blennow, Andre Strydom, Henrik Zetterberg, Marie-Claude Potier
ACTA NEUROPATHOLOGICA - 2024 -
Elevated plasma neurofilament light and glial fibrillary acidic protein in epilepsy versus nonepileptic seizures and nonepileptic
disorders
Hannah Dobson, Said Al Maawali, Charles Malpas, Alexander F. Santillo, Matthew Kang, Marian Todaro, Rosie Watson, Nawaf Yassi, Kaj Blennow, Henrik Zetterberg, Emma Foster, Andrew Neal, Dennis Velakoulis, Terence John O'Brien, Dhamidhu Eratne, Patrick Kwan
EPILEPSIA - 2024 -
CSF glial biomarkers are associated with cognition in individuals at risk of Alzheimer's
disease
Noelle Warmenhoven, Gonzalo Sanchez-Benavides, Armand Gonzalez-Escalante, Marta Mila-Aloma, Mahnaz Shekari, David Lopez-Martos, Paula Ortiz-Romero, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Carolina Minguillon, Juan Domingo Gispert, Natalia Vilor-Tejedor, Eider Arenaza-Urquijo, Eleni Palpatzis, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Marc Suarez-Calvet, Oriol Grau-Rivera
ALZHEIMERS & DEMENTIA - 2024 -
Quantification of neurofilament light and glial fibrillary acidic protein in finger-prick
blood
Magdalena A. Kolanko, Hanna Huber, Michael C. B. David, Laia Montoliu-Gaya, Joel Simrén, Kaj Blennow, Henrik Zetterberg, Ramin Nilforooshan, Paresh Malhotra, David J. Sharp, Nicholas J. Ashton, Neil S. N. Graham
BRAIN COMMUNICATIONS - 2024 -
Longitudinal plasma phosphorylated-tau217 and other related biomarkers in a non-demented Alzheimer's risk-enhanced
sample
Lianlian Du, Rebecca E. Langhough, Rachael E. Wilson, Ramiro Eduardo Rea Reyes, Bruce P. Hermann, Erin M. Jonaitis, Tobey J. Betthauser, Nathaniel A. Chin, Bradley Christian, Lauren Chaby, Andreas Jeromin, Guglielmo Di Molfetta, Wagner Scheeren Brum, Burak Arslan, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Sterling C. Johnson
ALZHEIMERS & DEMENTIA - 2024 -
Time-encoded ASL reveals lower cerebral blood flow in the early AD
continuum
Carles Falcon, Paula Montesinos, Lena Vaclavu, Michalis Kassinopoulos, Carolina Minguillon, Karine Fauria, Diego Cascales-Lahoz, Jose Contador, Aida Fernandez-Lebrero, Irene Navalpotro, Albert Puig-Pijoan, Oriol Grau-Rivera, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Jose Luis Molinuevo, Henrik Zetterberg, Kaj Blennow, Marc Suarez-Calvet, Matthias J. P. Van Osch, Javier Sanchez-Gonzalez, Juan Domingo Gispert
ALZHEIMERS & DEMENTIA - 2024 -
PTPRS is a novel marker for early Tau pathology and synaptic integrity in Alzheimer's
disease
Alexandre Poirier, Cynthia Picard, Anne Labonte, Isabelle Aubry, Daniel Auld, Henrik Zetterberg, Kaj Blennow, Michel L. Tremblay, Judes Poirier
SCIENTIFIC REPORTS - 2024 -
An interim exploratory proteomics biomarker analysis of a phase 2 clinical trial to assess the impact of CT1812 in Alzheimer's
disease
B. N. Lizama, H. A. North, K. Pandey, C. Williams, D. Duong, E. Cho, V. Di Caro, L. Ping, Kaj Blennow, Henrik Zetterberg, J. Lah, A. I. Levey, M. Grundman, A. O. Caggiano, N. T. Seyfried, M. E. Hamby
NEUROBIOLOGY OF DISEASE - 2024 -
Microstructural associations between locus coeruleus, cortical, and subcortical regions are modulated by astrocyte reactivity: a 7T MRI adult lifespan
study
Elise Beckers, Maxime Van Egroo, Nicholas J. Ashton, Kaj Blennow, Gilles Vandewalle, Henrik Zetterberg, Benedikt A. Poser, Heidi I. L. Jacobs
CEREBRAL CORTEX - 2024 -
KLOTHO KL-VS heterozygosity is associated with diminished age-related neuroinflammation, neurodegeneration, and synaptic dysfunction in older cognitively unimpaired
adults
Ira Frahmand Driscoll, Sarah Lose, Yue Ma, Barbara B. Bendlin, Catherine Gallagher, Sterling C. Johnson, Sanjay Asthana, Bruce Hermann, Mark A. Sager, Kaj Blennow, Henrik Zetterberg, Cynthia Carlsson, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Dena Dubal, Ozioma C. Okonkwo
ALZHEIMERS & DEMENTIA - 2024 -
Effects of time of the day at sampling on CSF and plasma levels of Alzheimer' disease
biomarkers
Anna Orduna Dolado, Erik Stomrud, Nicholas J. Ashton, Johanna Nilsson, Clara Quijano-Rubio, Alexander Jethwa, Wagner Scheeren Brum, Ann Brinkmalm-Westman, Henrik Zetterberg, Kaj Blennow, Shorena Janelidze, Oskar Hansson
ALZHEIMERS RESEARCH & THERAPY - 2024 -
Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer's
Disease
John A. Hey, Susan Abushakra, Kaj Blennow, Eric M. Reiman, Jakub Hort, Niels D. Prins, Katerina Sheardova, Patrick Kesslak, Larry Shen, Xinyi Zhu, Adem Albayrak, Jijo Paul, Jean F. Schaefer, Aidan Power, Martin Tolar
DRUGS - 2024 -
Evidence for reduced anti-inflammatory microglial phagocytic response in late-life major
depression
Chelsea Reichert Plaska, Amanda Heslegrave, Davide Bruno, Jaime Ramos-Cejudo, Sang Han Lee, Ricardo Osorio, Bruno P. Imbimbo, Henrik Zetterberg, Kaj Blennow, Nunzio Pomara
BRAIN BEHAVIOR AND IMMUNITY - 2024 -
Evidence of Pericyte Damage in a Cognitively Normal
Cohort
Arsalan Haghdel, Natasha Smith, Lidia Glodzik, Yi Li, Xiuyuan Wang, Tamara Crowder, Yuan-Shan Zhu, Tracy Butler, Kaj Blennow, Laura Beth Mcintire, Silky Pahlajani, Joseph Osborne, Gloria Chiang, Mony de Leon, Jana Ivanidze
ALZHEIMER DISEASE & ASSOCIATED DISORDERS - 2024 -
Acute Hyperglycemia Induced by Hyperglycemic Clamp Affects Plasma Amyloid-β in Type 2
Diabetes.
Olov Rolandsson, Andreas Tornevi, Pär Steneberg, Helena Edlund, Tommy Olsson, Ulf Andreasson, Henrik Zetterberg, Kaj Blennow
Journal of Alzheimer's disease : JAD - 2024 -
Post-GWAS multiomic functional investigation of the <i>TNIP1</i> locus in Alzheimer's disease highlights a potential role for
GPX3
Daniel J. Panyard, Lianne M. Reus, Muhammad Ali, Jihua Liu, Yuetiva K. Deming, Qiongshi Lu, Gwendlyn Kollmorgen, Margherita Carboni, Norbert Wild, Pieter J. Visser, Lars Bertram, Henrik Zetterberg, Kaj Blennow, Johan Gobom, Dan Western, Yun Ju Sung, Cynthia M. Carlsson, Sterling C. Johnson, Sanjay Asthana, Carlos Cruchaga, Betty M. Tijms, Corinne D. Engelman, Michael P. Snyder
ALZHEIMERS & DEMENTIA - 2024 -
Longitudinal trajectories of Alzheimer's disease CSF biomarkers and blood pressure in cognitively healthy
subjects
Adrienne Biskaduros, Lidia Glodzik, Leslie A. Saint Louis, Henry Rusinek, Elizabeth Pirraglia, Ricardo Osorio, Tracy Butler, Yi Li, Ke Xi, Emily Tanzi, Patrick Harvey, Henrik Zetterberg, Kaj Blennow, Mony J. de Leon
ALZHEIMERS & DEMENTIA - 2024 -
Variants in the MS4A cluster interact with soluble TREM2 expression on biomarkers of
neuropathology
Rebecca L. Winfree, Emma Nolan, Logan Dumitrescu, Kaj Blennow, Henrik Zetterberg, Katherine A. Gifford, Kimberly R. Pechman, Mabel Seto, Vladislav A. Petyuk, Yanling Wang, Julie Schneider, David A. Bennett, Angela L. Jefferson, Timothy J. Hohman
MOLECULAR NEURODEGENERATION - 2024 -
Alzheimer's Disease and Small Vessel Disease Differentially Affect White Matter
Microstructure
Mario Tranfa, Luigi Lorenzini, Lyduine E. Collij, David Vallez Garcia, Silvia Ingala, Giuseppe Pontillo, Leonard Pieperhoff, Alessio Maranzano, Robin Wolz, Sven Haller, Kaj Blennow, Giovanni Frisoni, Carole H. Sudre, Gael Chetelat, Michael Ewers, Pierre Payoux, Adam Waldman, Pablo Martinez-Lage, Adam J. Schwarz, Craig W. Ritchie, Joanna M. Wardlaw, Juan Domingo Gispert, Arturo Brunetti, Henk J. M. M. Mutsaerts, Alle Meije Wink, Frederik Barkhof
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY - 2024 -
Alzheimer blood biomarkers: practical guidelines for study design, sample collection, processing, biobanking, measurement and result
reporting
Xuemei Zeng, Yijun Chen, Anuradha Sehrawat, Jihui Lee, Tara K. Lafferty, Julia Kofler, Sarah B. Berman, Robert A. Sweet, Dana L. Tudorascu, William E. Klunk, Milos D. Ikonomovic, Anna Pfister, Henrik Zetterberg, Beth E. Snitz, Anne D. Cohen, Victor L. Villemagne, Tharick A. Pascoal, M. llyas Kamboh, Oscar I. Lopez, Kaj Blennow, Thomas Karikari
MOLECULAR NEURODEGENERATION - 2024 -
Moving Beyond Depression: Mood Symptoms Across the Spectrum Relate to Tau Pathology in Older Women at Risk for Alzheimer's
Disease
Nargis Ahmadi, Melanie A. Dratva, Nadine Heyworth, Xin Wang, Kaj Blennow, Sarah J. Banks, Erin E. Sudermann
INTERNATIONAL JOURNAL OF AGING & HUMAN DEVELOPMENT - 2024 -
Biomarkers and genotypes in patients with Central nervous system infection caused by
enterovirus
Karolina Alsén, Marianela Patzi Churqui, Helene Norder, Karolina Rembeck, Henrik Zetterberg, Kaj Blennow, Fredrika Sahlgren, Anna Grahn
INFECTIOUS DISEASES - 2024 -
Plasma biomarkers increase diagnostic confidence in patients with Alzheimer's disease or frontotemporal lobar
degeneration.
Daniele Altomare, Ilenia Libri, Antonella Alberici, Jasmine Rivolta, Alessandro Padovani, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Barbara Borroni
Alzheimer's research & therapy - 2024 -
Widespread White Matter Abnormalities in Concussed Athletes Detected by 7T Diffusion Magnetic Resonance
Imaging.
Anna Gard, Evgenios N Kornaropoulos, Maria Portonova Wernersson, Ia Rorsman, Kaj Blennow, Henrik Zetterberg, Yelverton Tegner, Alessandro De Maio, Karin Markenroth Bloch, Isabella Björkman-Burtscher, Hélène Pessah-Rasmussen, Markus Nilsson, Niklas Marklund
Journal of Neurotrauma - 2024 -
Insulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer
brains.
Marc James Quesnel, Anne Labonté, Cynthia Picard, Henrik Zetterberg, Kaj Blennow, Ann Brinkmalm-Westman, Sylvia Villeneuve, Judes Poirier
Brain : a journal of neurology - 2024 -
Personalized whole-brain neural mass models reveal combined Aβ and tau hyperexcitable influences in Alzheimer's
disease.
Lazaro M Sanchez-Rodriguez, Gleb Bezgin, Felix Carbonell, Joseph Therriault, Jaime Fernandez-Arias, Stijn Servaes, Nesrine Rahmouni, Cécile Tissot, Jenna Stevenson, Thomas K Karikari, Nicholas J. Ashton, Andréa Lessa Benedet, Henrik Zetterberg, Kaj Blennow, Gallen Triana-Baltzer, Hartmuth C Kolb, Pedro Rosa-Neto, Yasser Iturria-Medina
Communications biology - 2024 -
Cerebrospinal fluid reference proteins increase accuracy and interpretability of biomarkers for brain
diseases.
Linda Karlsson, Jacob Vogel, Ida Arvidsson, Kalle Åström, Shorena Janelidze, Kaj Blennow, Sebastian Palmqvist, Erik Stomrud, Niklas Mattsson-Carlgren, Oskar Hansson
Nature Communications - 2024 -
Chronic immunosuppression across 12 months and high ability of acute and subacute CNS-injury biomarker concentrations to identify individuals with complicated mTBI on acute CT and
MRI.
Gerard Janez Brett Clarke, Turid Follestad, Toril Skandsen, Henrik Zetterberg, Anne Vik, Kaj Blennow, Alexander Olsen, Asta Kristine Håberg
Journal of Neuroinflammation - 2024 -
Neurofilaments in Sporadic and Familial Amyotrophic Lateral Sclerosis: A Systematic Review and
Meta-Analysis.
Pashtun Shahim, Gina Norato, Ninet Sinaii, Henrik Zetterberg, Kaj Blennow, Leighton Chan, Christopher Grunseich
Genes - 2024 -
Proportion of Community-Dwelling Individuals Older Than 70 Years Eligible for Lecanemab Initiation: The Gothenburg H70 Birth Cohort
Study.
Anna Dittrich, Eric Westman, Sara Shams, Tobias Skillbäck, Henrik Zetterberg, Kaj Blennow, Anna Zettergren, Ingmar Skoog, Silke Kern
Neurology - 2024 -
Neurofilaments as biomarkers in neurological disorders - towards clinical
application.
Michael Khalil, Charlotte E Teunissen, Sylvain Lehmann, Markus Otto, Fredrik Piehl, Tjalf Ziemssen, Stefan Bittner, Maria Pia Sormani, Thomas Gattringer, Samir Abu-Rumeileh, Simon Thebault, Ahmed Abdelhak, Ari Green, Pascal Benkert, Ludwig Kappos, Manuel Comabella, Hayrettin Tumani, Mark S Freedman, Axel Petzold, Kaj Blennow, Henrik Zetterberg, David Leppert, Jens Kuhle
Nature Reviews Neurology - 2024 -
Plasma Phosphorylated Tau 231 Increases at One-Year Intervals in Cognitively Unimpaired
Subjects
Francisco Martinez-Dubarbie, Sara Lopez-Garcia, Carmen Lage, Guglielmo Di Molfetta, Marta Fernandez-Matarrubia, Ana Pozueta-Cantudo, Maria Garcia-Martinez, Andrea Corrales-Pardo, Maria Bravo, Julio Jimenez-Bonilla, Remedios Quirce, Enrique Marco de Lucas, Marta Drake-Perez, Diana Tordesillas, Marcos Lopez-Hoyos, Juan Irure-Ventura, Elizabeth Valeriano-Lorenzo, Kaj Blennow, Nicholas J. Ashton, Henrik Zetterberg, Eloy Rodriguez-Rodriguez, Pascual Sanchez-Juan
JOURNAL OF ALZHEIMERS DISEASE - 2024 -
Sex-specific modulation of amyloid-β on tau phosphorylation underlies faster tangle accumulation in
females
Yi-Ting Wang, Joseph Therriault, Stijn Servaes, Cécile Tissot, Nesrine Rahmouni, Arthur Cassa Macedo, Jaime Fernandez-Arias, Sulantha S Mathotaarachchi, Andréa Lessa Benedet, Jenna Stevenson, Nicholas J. Ashton, Firoza Z Lussier, Tharick A Pascoal, Henrik Zetterberg, Maria Natasha Rajah, Kaj Blennow, Serge Gauthier, Pedro Rosa-Neto
Brain : a journal of neurology - 2024 -
Association of plasma GFAP with elevated brain amyloid is dependent on severity of white matter lesions in an Asian cognitively impaired
cohort.
Joyce R Chong, Yuek Ling Chai, Amelia T Y Yam, Saima Hilal, Henri Vrooman, Narayanaswamy Venketasubramanian, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Christopher P Chen, Mitchell K P Lai
Alzheimer's & dementia (Amsterdam, Netherlands) - 2024 -
Plasma glial fibrillary acidic protein and tau: predictors of neurological outcome after cardiac
arrest.
Isabelle Arctaedius, Helena Levin, Bergthóra Thorgeirsdóttir, Marion Moseby-Knappe, Tobias Cronberg, Martin Annborn, Niklas Nielsen, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Attila Frigyesi, Hans Friberg, Anna Lybeck, Niklas Mattsson-Carlgren
Critical care (London, England) - 2024 -
Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer's
disease.
Fernando Gonzalez-Ortiz, Bjørn-Eivind Kirsebom, José Contador, Jordan E Tanley, Per Selnes, Berglind Gísladóttir, Lene Pålhaugen, Mathilde Suhr Hemminghyth, Jonas Jarholm, Ragnhild Skogseth, Geir Bråthen, Gøril Grøndtvedt, Atle Bjørnerud, Sandra Tecelao, Knut Waterloo, Dag Aarsland, Aida Fernández-Lebrero, Greta García-Escobar, Irene Navalpotro-Gómez, Michael Turton, Agnes Hesthamar, Przemyslaw R. Kac, Johanna Nilsson, Jose Luchsinger, Kathleen M Hayden, Peter Harrison, Albert Puig-Pijoan, Henrik Zetterberg, Timothy M Hughes, Marc Suárez-Calvet, Thomas Karikari, Tormod Fladby, Kaj Blennow
Nature communications - 2024 -
Plasma neurofilament light chain is increased in Niemann-Pick Type C but glial fibrillary acidic protein remains
normal
Dhamidhu Eratne, Courtney Lewis, Wendy Kelso, Samantha Loi, Wei-Hsuan Michelle Chiu, Kaj Blennow, Henrik Zetterberg, Alexander F. Santillo, Dennis Velakoulis, Mark Walterfang
ACTA NEUROPSYCHIATRICA - 2024 -
Novel ultrasensitive immunoassay for the selective quantification of tau oligomers and related soluble
aggregates
Tohidul Islam, Hlin Kvartsberg, Anuradha Sehrawat, Przemyslaw R. Kac, Bruno Becker, Maria Olsson, Eric E. Abrahamson, Henrik Zetterberg, Milos D. Ikonomovic, Kaj Blennow, Thomas Karikari
ALZHEIMERS & DEMENTIA - 2024 -
Association of Plasma Brain-Derived Tau With Functional Outcome After Ischemic
Stroke.
Tara M Stanne, Fernando Gonzalez-Ortiz, Cecilia Brännmark, Katarina Jood, Thomas Karikari, Kaj Blennow, Christina Jern
Neurology - 2024 -
Plasma p-tau212 antemortem diagnostic performance and prediction of autopsy verification of Alzheimer's disease
neuropathology.
Przemyslaw R. Kac, Fernando Gonzalez-Ortiz, Andreja Emeršič, Maciej Dulewicz, Srinivas Koutarapu, Michael Turton, Yang An, Denis Smirnov, Agnieszka Kulczyńska-Przybik, Vijay R Varma, Nicholas J. Ashton, Laia Montoliu-Gaya, Elena Camporesi, Izabela Winkel, Bogusław Paradowski, Abhay Moghekar, Juan C Troncoso, Tammaryn Lashley, Gunnar Brinkmalm, Susan M Resnick, Barbara Mroczko, Hlin Kvartsberg, Milica Gregorič Kramberger, Jörg Hanrieder, Saša Čučnik, Peter Harrison, Henrik Zetterberg, Piotr Lewczuk, Madhav Thambisetty, Uroš Rot, Douglas Galasko, Kaj Blennow, Thomas Karikari
Nature communications - 2024 -
Serum neurofilament light for detecting disease activity in individual patients in multiple sclerosis: A 48-week prospective single-center
study
Magnus Johnsson, Y. T. Stenberg, H. H. Farman, Kaj Blennow, Henrik Zetterberg, Clas Malmeström, Sofia Sandgren, Igal Rosenstein, Jan Lycke, Markus Axelsson, Lenka Novakova
MULTIPLE SCLEROSIS JOURNAL - 2024 -
A blood-based biomarker workflow for optimal tau-PET referral in memory clinic
settings.
Wagner Scheeren Brum, Nicholas C Cullen, Joseph Therriault, Shorena Janelidze, Nesrine Rahmouni, Jenna Stevenson, Stijn Servaes, Andréa Lessa Benedet, Eduardo R Zimmer, Erik Stomrud, Sebastian Palmqvist, Henrik Zetterberg, Giovanni B Frisoni, Nicholas J. Ashton, Kaj Blennow, Niklas Mattsson-Carlgren, Pedro Rosa-Neto, Oskar Hansson
Nature Communications - 2024 -
Lifetime Stressful Events Associated with Alzheimer's Pathologies, Neuroinflammation and Brain Structure in a Risk Enriched
Cohort
Eleni Palpatzis, Muge Akinci, Pablo Aguilar-Dominguez, Marina Garcia-Prat, Kaj Blennow, Henrik Zetterberg, Margherita Carboni, Gwendlyn Kollmorgen, Norbert Wild, Karine Fauria, Carles Falcon, Juan Domingo Gispert, Marc Suarez-Calvet, Oriol Grau-Rivera, Gonzalo Sanchez-Benavides, Eider M. Arenaza-Urquijo
ANNALS OF NEUROLOGY - 2024 -
Comparison of two plasma p-tau217 assays to detect and monitor Alzheimer's
pathology.
Joseph Therriault, Nicholas J. Ashton, Ilaria Pola, Gallen Triana-Baltzer, Wagner Scheeren Brum, Guglielmo Di Molfetta, Burak Arslan, Nesrine Rahmouni, Cecile Tissot, Stijn Servaes, Jenna Stevenson, Arthur Cassa Macedo, Tharick Ali Pascoal, Hartmuth Christian Kolb, Andreas Jeromin, Kaj Blennow, Henrik Zetterberg, Pedro Rosa-Neto, Andréa Lessa Benedet
EBioMedicine - 2024 -
Low CD4 + T cell count is related to specific anti-nuclear antibodies, IFNα protein positivity and disease activity in systemic lupus erythematosus
pregnancy.
Agnes Torell, Marit Stockfelt, Kaj Blennow, Henrik Zetterberg, Tansim Akhter, Dag Leonard, Lars Rönnblom, Sofia Pihl, Muna Saleh, Christopher Sjöwall, Helena Strevens, Andreas Jönsen, Anders A Bengtsson, Estelle Trysberg, Maria Majczuk Sennström, Agneta Zickert, Elisabet Svenungsson, Iva Gunnarsson, Johan Bylund, Bo Jacobsson, Anna Rudin, Anna-Carin Lundell
Arthritis research & therapy - 2024 -
Spatial neurolipidomics-MALDI mass spectrometry imaging of lipids in brain
pathologies.
Durga Jha, Kaj Blennow, Henrik Zetterberg, Jeffrey N Savas, Jörg Hanrieder
Journal of mass spectrometry : JMS - 2024 -
Diffusion MRI tracks cortical microstructural changes during the early stages of Alzheimer's
disease.
Nicola Spotorno, Olof Strandberg, Erik Stomrud, Shorena Janelidze, Kaj Blennow, Markus Nilsson, Danielle van Westen, Oskar Hansson
Brain : a journal of neurology - 2024 -
Repetitive head injuries in German American football players do not change blood-based biomarker candidates for CTE during a single
season
Theres Bastgen, Janis Evers, Christiane Oedekoven, Caroline Weide, Lars Herzog, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Alexandra Albus, Natasha Vidovic, Oliver Kraff, Cornelius Deuschl, Richard Dodel, J. Alexander Ross
NEUROLOGICAL RESEARCH AND PRACTICE - 2024 -
Association of CSF biomarkers with MRI brain changes in Alzheimer's
disease
Nazib Seidu, Silke Kern, Simona Sacuiu, Therese Rydberg Sterner, Kaj Blennow, Henrik Zetterberg, Olof Lindberg, Daniel Ferreira, Eric Westman, Anna Zettergren, Ingmar Skoog
ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING - 2024 -
Profiling amyloid-β peptides as biomarkers for cerebral amyloid
angiopathy
Emma van den Berg, Iris Kersten, Gunnar Brinkmalm, Kjell Johansson, Anna M. de Kort, Catharina J. M. Klijn, Floris H. B. M. Schreuder, Johan Gobom, Erik Stoops, Erik Portelius, Eleni Gkanatsiou, Henrik Zetterberg, Kaj Blennow, Hinke B. Kuiperij, Marcel M. Verbeek
JOURNAL OF NEUROCHEMISTRY - 2024 -
Cognitively healthy APOE4/4 carriers show white matter impairment associated with serum NfL and
amyloid-PET.
Claudia Tato-Fernández, Laura L Ekblad, Elina Pietilä, Virva Saunavaara, Semi Helin, Riitta Parkkola, Henrik Zetterberg, Kaj Blennow, Juha O Rinne, Anniina Snellman
Neurobiology of Disease - 2024 -
Inflammatory biomarkers for neurobehavioral dysregulation in former American football players: findings from the DIAGNOSE CTE Research
Project
Suzan van Amerongen, Surya V. Pulukuri, Fatima Tuz-Zahra, Yorghos Tripodis, Jonathan D. Cherry, Charles Bernick, Yonas E. Geda, Jennifer V. Wethe, Douglas I. Katz, Michael L. Alosco, Charles H. Adler, Laura J. Balcer, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Daniel H. Daneshvar, Elizabeth A. Colasurdo, Jeffrey J. Iliff, Gail Li, Elaine R. Peskind, Martha E. Shenton, Eric M. Reiman, Jeffrey L. Cummings, Robert A. Stern
JOURNAL OF NEUROINFLAMMATION - 2024 -
Analytical and clinical validation of Alzheimer's disease blood biomarkers with a focus on plasma
p-tau217.
Fernando Gonzalez-Ortiz, Thomas Karikari, Kaj Blennow
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2024 -
Biomarker-based staging of Alzheimer disease: rationale and clinical
applications.
Joseph Therriault, Suzanne E Schindler, Gemma Salvadó, Tharick A Pascoal, Andréa Lessa Benedet, Nicholas J. Ashton, Thomas Karikari, Liana Apostolova, Melissa E Murray, Inge Verberk, Jacob W Vogel, Renaud La Joie, Serge Gauthier, Charlotte Teunissen, Gil D Rabinovici, Henrik Zetterberg, Randall J Bateman, Philip Scheltens, Kaj Blennow, Reisa Sperling, Oskar Hansson, Clifford R Jack, Pedro Rosa-Neto
Nature reviews. Neurology - 2024 -
Plasma biomarkers of Alzheimer's disease and related dementias in American Indians: The Strong Heart
Study
Astrid M. Suchy-Dicey, W. T. Longstreth, Kristoffer Rhoads, Jason Umans, Dedra Buchwald, Thomas Grabowski, Kaj Blennow, Eric Reiman, Henrik Zetterberg
Alzheimer's and Dementia - 2024 -
Plasma neurofilament light, glial fibrillary acid protein, and phosphorylated tau 181 as biomarkers for neuropsychiatric symptoms and related clinical disease
progression
Miriam Rabl, Leonardo Zullo, Piotr Lewczuk, Johannes Kornhuber, Thomas Karikari, Kaj Blennow, Henrik Zetterberg, Francesco Bavato, Boris B. Quednow, Erich Seifritz, Armin von Gunten, Christopher Clark, Julius Popp
ALZHEIMERS RESEARCH & THERAPY - 2024 -
Biomarkers of Alzheimer's disease and neurodegeneration in dried blood spots-A new collection method for remote
settings
Hanna Huber, Kaj Blennow, Henrik Zetterberg, Merce Boada, Andreas Jeromin, Haley Weninger, Raul Nunez-Llaves, Nuria Aguilera, Maribel Ramis, Joel Simrén, Johanna Nilsson, Juan Lantero Rodriguez, Adelina Orellana, Fernando Garcia-Gutierrez, Xavier Morato, Nicholas J. Ashton, Laia Montoliu-Gaya
ALZHEIMERS & DEMENTIA - 2024 -
Awareness of episodic memory and meta-cognitive profiles: associations with cerebrospinal fluid biomarkers at the preclinical stage of the Alzheimer’s
continuum
David López-Martos, Marc Suárez-Calvet, Marta Milà-Alomà, Juan Domingo Gispert, Carolina Minguillon, Clara Quijano-Rubio, Gwendlyn Kollmorgen, Henrik Zetterberg, Kaj Blennow, Oriol Grau-Rivera, Gonzalo Sánchez-Benavides
Frontiers in Aging Neuroscience - 2024 -
Head-to-head study of diagnostic accuracy of plasma and cerebrospinal fluid p-tau217 versus p-tau181 and p-tau231 in a memory clinic
cohort
Augusto J. Mendes, Federica Ribaldi, Aurelien Lathuiliere, Nicholas J. Ashton, Shorena Janelidze, Henrik Zetterberg, Max Scheffler, Frederic Assal, Valentina Garibotto, Kaj Blennow, Oskar Hansson, Giovanni B. Frisoni
JOURNAL OF NEUROLOGY - 2024 -
Correction to: Neurofilament light in plasma is a potential biomarker of central nervous system involvement in systemic lupus
erythematosus.
Maria Boge Lauvsnes, Henrik Zetterberg, Kaj Blennow, Jan Terje Kvaløy, Anne Bolette Tjensvoll, Stian Maroni, Mona K Beyer, Ole Jacob Greve, Ingeborg Kvivik, Guido Alves, Lasse Gunnar Gøransson, Erna Harboe, Shunsei Hirohata, Roald Omdal
Journal of Neurology - 2024 -
Late Blood Levels of Neurofilament Light Correlate With Outcome in Patients With Traumatic Brain
Injury.
Juho Tuure, Mehrbod Mohammadian, Olli Tenovuo, Kaj Blennow, Iftakher Hossain, Peter Hutchinson, Henna-Riikka Maanpää, David K Menon, Virginia F Newcombe, Riikka S K Takala, Jussi Tallus, Mark van Gils, Henrik Zetterberg, Jussi P Posti
Journal of Neurotrauma - 2024 -
Changes in Cerebrospinal Fluid Proteins across the Spectrum of Untreated and Treated Chronic HIV-1
Infection.
Zicheng Hu, Paola Cinque, Ameet Dravid, Lars Hagberg, Aylin Yilmaz, Henrik Zetterberg, Dietmar Fuchs, Johanna Gostner, Kaj Blennow, Serena S Spudich, Laura Kincer, Shuntai Zhou, Sarah Joseph, Ronald Swanstrom, Richard W Price, Magnus Gisslén
bioRxiv : the preprint server for biology - 2024 -
CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized
mice
María Latorre-Leal, Patricia Rodriguez-Rodriguez, Luca Franchini, Orestis Nikolidakis, Makrina Daniilidou, Ljerka Delac, Mukesh K. Varshney, Luis E. Arroyo-García, Francesca Eroli, Bengt Winblad, Kaj Blennow, Henrik Zetterberg, Miia Kivipelto, Manuela Pacciarini, Yuqin Wang, William J. Griffiths, Ingemar Björkhem, Anna Matton, Ivan Nalvarte, Paula Merino-Serrais, Angel Cedazo-Minguez, Silvia Maioli
Science advances - 2024 -
Optimal blood tau species for the detection of Alzheimer's disease neuropathology: an immunoprecipitation mass spectrometry and autopsy
study.
Laia Montoliu-Gaya, Michael L Alosco, Eukyung Yhang, Yorghos Tripodis, Daniel Sconzo, Madeline Ally, Lana Grötschel, Nicholas J. Ashton, Juan Lantero Rodriguez, Mathias Sauer, Bárbara Fernandes Gomes, Johanna Nilsson, Gunnar Brinkmalm, Michael A Sugarman, Hugo J Aparicio, Brett Martin, Joseph N Palmisano, Eric G Steinberg, Irene Simkin, Katherine W Turk, Andrew E Budson, Rhoda Au, Lindsay Farrer, Gyungah R Jun, Neil W Kowall, Robert A Stern, Lee E Goldstein, Wei Qiao Qiu, Jesse Mez, Bertrand Russell Huber, Victor E Alvarez, Ann C McKee, Henrik Zetterberg, Johan Gobom, Thor D Stein, Kaj Blennow
Acta neuropathologica - 2024 -
COVID-19 Recovery: Consistent Absence of Cerebrospinal Fluid Biomarker Abnormalities in Patients With Neurocognitive Post-COVID
Complications.
Nelly Kanberg, Anna Grahn, Erika Stentoft, Daniel Bremell, Aylin Yilmaz, Marie Studahl, Staffan Nilsson, Michael Schöll, Johanna M Gostner, Kaj Blennow, Henrik Zetterberg, Nikhil Padmanabhan, Rachel Cohen, Salvia Misaghian, Daniel Romero, Christopher Campbell, Anu Mathew, Mingyue Wang, George Sigal, Martin Stengelin, Arvid Edén, Magnus Gisslén
The Journal of infectious diseases - 2024 -
Levels of plasma brain-derived tau and p-tau181 in Alzheimer's disease and rapidly progressive
dementias.
Fernando Gonzalez-Ortiz, Thomas Karikari, Giuseppe Mario Bentivenga, Simone Baiardi, Angela Mammana, Michael Turton, Przemyslaw R. Kac, Andrea Mastrangelo, Peter Harrison, Sabina Capellari, Henrik Zetterberg, Kaj Blennow, Piero Parchi
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2024 -
A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's
disease.
Fernando Gonzalez-Ortiz, Pamela C L Ferreira, Armand González-Escalante, Laia Montoliu-Gaya, Paula Ortiz-Romero, Przemyslaw R. Kac, Michael Turton, Hlin Kvartsberg, Nicholas J. Ashton, Henrik Zetterberg, Peter Harrison, Bruna Bellaver, Guilherme Povala, Victor L Villemagne, Tharick A Pascoal, Mary Ganguli, Anne D Cohen, Carolina Minguillon, Jose Contador, Marc Suárez-Calvet, Thomas Karikari, Kaj Blennow
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2024 -
Neuro-Specific and Immuno-Inflammatory Biomarkers in Umbilical Cord Blood in Neonatal Hypoxic-Ischemic
Encephalopathy.
Hanna Toorell, Ylva Carlsson, BouBou Hallberg, Mairead N O'Riordian, Brian Henry Walsh, Marc Paul O'Sullivan, Geraldine B Boylan, Henrik Zetterberg, Kaj Blennow, Deirdre Murray, Henrik Hagberg
Neonatology - 2024 -
Outlier analysis for acute blood biomarkers of moderate and severe traumatic brain
injury
Otto Korhonen, Malla Mononen, Mehrbod Mohammadian, Olli Tenovuo, Kaj Blennow, Iftakher Hossain, Peter Hutchinson, Henna Riikka Maanpää, David K. Menon, Virginia F. Newcombe, Jean Charles Sanchez, Riikka S.K. Takala, Jussi Tallus, Mark Van Gils, Henrik Zetterberg, Jussi P. Posti
Journal of Neurotrauma - 2024 -
Longitudinal Associations Between Persistent Post-Concussion Symptoms and Blood Biomarkers of Inflammation and CNS-Injury Following Mild Traumatic Brain
Injury
Gerard Clarke, Toril Skandsen, Henrik Zetterberg, Turid Follestad, Cathrine Einarsen, Anne Vik, Tom Eirik Mollnes, Soeren Erik Pischke, Kaj Blennow, Asta Kristine Håberg
Journal of neurotrauma - 2024 -
Effect of Neprilysin Inhibition on Alzheimer Disease Plasma Biomarkers: A Secondary Analysis of a Randomized Clinical
Trial
Wagner Scheeren Brum, Kieran F Docherty, Nicholas J. Ashton, Henrik Zetterberg, Oskar Hansson, John J V McMurray, Kaj Blennow
JAMA neurology - 2024 -
Plasma Biomarker Strategy for Selecting Patients With Alzheimer Disease for Antiamyloid
Immunotherapies
Niklas Mattsson-Carlgren, Lyduine E Collij, Erik Stomrud, Alexa Pichet Binette, Rik Ossenkoppele, Ruben Smith, Linda Karlsson, Juan Lantero Rodriguez, Anniina Snellman, Olof Strandberg, Sebastian Palmqvist, Nicholas J. Ashton, Kaj Blennow, Shorena Janelidze, Oskar Hansson
JAMA neurology - 2024 -
Seroreactivity against lytic, latent and possible cross-reactive EBV antigens appears on average 10 years before MS induced preclinical neuroaxonal
damage.
Daniel Jons, Viktor Grut, Tomas Bergström, Henrik Zetterberg, Martin Biström, Martin Gunnarsson, Magnus Vrethem, Nicole Brenner, Julia Butt, Kaj Blennow, Staffan Nilsson, Ingrid Kockum, Tomas Olsson, Tim Waterboer, Peter Sundström, Oluf Andersen
Journal of neurology, neurosurgery, and psychiatry - 2024 -
Plasma GFAP and its association with disease severity in Huntington's
disease.
Kübra Tan, Melanie Alpaugh, Nicholas J. Ashton, Sylvain Chouinard, Roger A Barker, Kaj Blennow, Henrik Zetterberg, Francesca Cicchetti, Andréa Lessa Benedet
Journal of neurology - 2024 -
The neutrophil to lymphocyte ratio associates with markers of Alzheimer's disease pathology in cognitively unimpaired elderly
people.
Tovia Jacobs, Sean R Jacobson, Juan Fortea, Jeffrey S Berger, Alok Vedvyas, Karyn Marsh, Tianshe He, Eugenio Gutierrez-Jimenez, Nathanael R Fillmore, Omonigho M Bubu, Moses Gonzalez, Luisa Figueredo, Naomi L Gaggi, Chelsea Reichert Plaska, Nunzio Pomara, Esther Blessing, Rebecca Betensky, Henry Rusinek, Henrik Zetterberg, Kaj Blennow, Lidia Glodzik, Thomas M Wisniewski, Mony J Leon, Ricardo S Osorio, Jaime Ramos-Cejudo
Research square - 2024 -
Differential patterns of lysosomal dysfunction are seen in the clinicopathological forms of primary progressive
aphasia
I. J. Swift, Simon Sjödin, Johan Gobom, Ann Brinkmalm, Kaj Blennow, Henrik Zetterberg, J. D. Rohrer, A. Sogorb-Esteve
Journal of Neurology - 2024 -
Plasma pTau-217 and N-terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid-β positive
individuals
M. S. Woo, C. Tissot, Juan Lantero Rodriguez, Anniina Snellman, J. Therriault, N. Rahmouni, A. C. Macedo, S. Servaes, Y. T. Wang, J. F. Arias, S. A. Hosseini, M. Chamoun, F. Z. Lussier, Andréa Lessa Benedet, Nicholas J. Ashton, T. K. Karikari, G. Triana-Baltzer, H. C. Kolb, J. Stevenson, C. Mayer, E. Kobayashi, G. Massarweh, M. A. Friese, T. A. Pascoal, S. Gauthier, Henrik Zetterberg, Kaj Blennow, P. Rosa-Neto
Alzheimers & Dementia - 2024 -
CT-based volumetric measures obtained through deep learning: Association with biomarkers of
neurodegeneration
Meera Srikrishna, Nicholas J. Ashton, Alexis Moscoso Rial, J. B. Pereira, Rolf A. Heckemann, D. van Westen, Giovanni Volpe, Joel Simrén, Anna Zettergren, Silke Kern, L. O. Wahlund, B. Gyanwali, S. Hilal, J. C. Ruifen, Henrik Zetterberg, Kaj Blennow, E. Westman, C. S. P. Chen, Ingmar Skoog, Michael Schöll
Alzheimers & Dementia - 2024 -
Development and multi-center validation of a fully automated digital immunoassay for neurofilament light chain: toward a clinical blood test for neuronal
injury
D. Wilson, D. D. Chan, L. Chang, R. Mathis, I. Verberk, X. Montalban, M. Comabella, N. Fissolo, B. Bielekova, R. Masvekar, T. Chitnis, T. Ziemssen, K. Akguen, Kaj Blennow, Henrik Zetterberg, W. Brueck, G. Giovannoni, S. Gnanapavan, S. Bittner, F. Zipp, G. Comi, R. Furlan, S. Lehmann, S. Thebault, M. Freedman, A. Bar-Or, M. Kramer, M. Otto, S. Halbgebauer, K. Hrusovsky, T. Plavina, M. Khalil, F. Piehl, H. Wiendl, L. Kappos, A. Maceski, E. Willemse, D. Leppert, C. Teunissen, J. Kuhle
Clinical Chemistry and Laboratory Medicine - 2024 -
Plasma p-tau181 as an outcome and predictor of multidomain intervention effects: a secondary analysis of a randomised, controlled, dementia prevention
trial
Nicola Coley, Henrik Zetterberg, Christelle Cantet, Sophie Guyonnet, Nicholas J. Ashton, Bruno Vellas, Kaj Blennow, Sandrine Andrieu, Isabelle Carrié, Lauréane Brigitte, Catherine Faisant, Françoise Lala, Julien Delrieu, Hélène Villars, Emeline Combrouze, Carole Badufle, Audrey Zueras, Christophe Morin, Gabor Abellan Van Kan, Charlotte Dupuy, Yves Rolland, Céline Caillaud, Pierre Jean Ousset, Sherry Willis, Sylvie Belleville, Brigitte Gilbert, Francine Fontaine, Jean François Dartigues, Isabelle Marcet, Fleur Delva, Alexandra Foubert, Sandrine Cerda, Marie Noëlle Cuffi, Corinne Costes, Olivier Rouaud, Patrick Manckoundia, Valérie Quipourt, Sophie Marilier, Evelyne Franon, Lawrence Bories, Marie Laure Pader, Marie France Basset, Bruno Lapoujade, Valérie Faure, Michael Li Yung Tong, Christine Malick-Loiseau, Evelyne Cazaban-Campistron, Françoise Desclaux, Colette Blatge, Thierry Dantoine, Cécile Laubarie-Mouret, Isabelle Saulnier, Jean Pierre Clément, Marie Agnès Picat, Laurence Bernard-Bourzeix, Stéphanie Willebois, Iléana Désormais, Noëlle Cardinaud, Marc Bonnefoy, Pierre Livet, Pascale Rebaudet, Claire Gédéon, Catherine Burdet, Flavien Terracol, Alain Pesce, Stéphanie Roth, Sylvie Chaillou, Sandrine Louchart, Kristel Sudres, Nicolas Lebrun, Nadège Barro-Belaygues, Jacques Touchon, Karim Bennys, Audrey Gabelle, Aurélia Romano, Lynda Touati, Cécilia Marelli, Cécile Pays, Philippe Robert, Franck Le Duff, Claire Gervais, Sébastien Gonfrier, Yannick Gasnier, Serge Bordes, Danièle Begorre, Christian Carpuat, Khaled Khales, Jean François Lefebvre, Samira Misbah El Idrissi, Pierre Skolil, Jean Pierre Salles, Carole Dufouil, Stéphane Lehéricy, Marie Chupin, Jean François Mangin, Ali Bouhayia, Michèle Allard, Frédéric Ricolfi, Dominique Dubois, Marie Paule Bonceour Martel
The Lancet Healthy Longevity - 2024 -
Preliminary Evaluation of the Scandinavian Guidelines for Initial Management of Minimal, Mild, and Moderate Head Injuries with Glial Fibrillary Acidic
Protein
Mira Keski-Pukkila, Justin E. Karr, Jussi P. Posti, Ksenia Berghem, Anna-Kerttu Kotilainen, Kaj Blennow, Henrik Zetterberg, Grant L. Iverson, Teemu M. Luoto
NEUROTRAUMA REPORTS - 2024 -
Biological variation estimates of Alzheimer's disease plasma biomarkers in healthy
individuals
Wagner Scheeren Brum, Nicholas J. Ashton, Joel Simrén, Guiglielmo di Molfetta, Thomas Karikari, Andréa Lessa Benedet, Eduardo R. Zimmer, Juan Lantero Rodriguez, Laia Montoliu-Gaya, Andreas Jeromin, Aasne K. Aarsand, William A. Bartlett, Pilar Fernández Calle, Abdurrahman Coşkun, Jorge Díaz–Garzón, Niels Jonker, Henrik Zetterberg, Sverre Sandberg, Anna Carobene, Kaj Blennow
Alzheimer's and Dementia - 2024 -
Plasma N-terminal containing tau fragments (NTA-tau): a biomarker of tau deposition in Alzheimer's
Disease
Juan Lantero Rodriguez, Gemma Salvado, Anniina Snellman, Laia Montoliu-Gaya, Wagner Scheeren Brum, Andréa Lessa Benedet, Niklas Mattsson-Carlgren, Pontus Tideman, Shorena Janelidze, Sebastian Palmqvist, Erik Stomrud, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Oskar Hansson
MOLECULAR NEURODEGENERATION - 2024 -
Day-to-day sleep variability with Alzheimer's biomarkers in at-risk
elderly
Andree-Ann Baril, Cynthia Picard, Anne Labonte, Erlan Sanchez, Catherine Duclos, Bery Mohammediyan, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, John C. S. Breitner, Sylvia Villeneuve, Judes Poirier
ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING - 2024 -
Spatial Neurolipidomics at the Single Amyloid-β Plaque Level in Postmortem Human Alzheimer's Disease
Brain
Wojciech Michno, Andrew Bowman, Durga Jha, Karolina Minta, Junyue Ge, Srinivas Koutarapu, Henrik Zetterberg, Kaj Blennow, Tammaryn Lashley, Ron M. A. Heeren, Jörg Hanrieder
ACS CHEMICAL NEUROSCIENCE - 2024 -
Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease
Pathology
Nicholas J. Ashton, Wagner Scheeren Brum, Guglielmo Di Molfetta, Andréa Lessa Benedet, Burak Arslan, Erin Jonaitis, Rebecca E. Langhough, Karly Cody, Rachael Wilson, Cynthia M. Carlsson, Eugeen Vanmechelen, Laia Montoliu-Gaya, Juan Lantero Rodriguez, Nesrine Rahmouni, Cecile Tissot, Jenna Stevenson, Stijn Servaes, Joseph Therriault, Tharick Pascoal, Alberto Lleo, Daniel Alcolea, Juan Fortea, Pedro Rosa-Neto, Sterling Johnson, Andreas Jeromin, Kaj Blennow, Henrik Zetterberg
JAMA NEUROLOGY - 2024 -
Biomarkers of Alzheimer's Disease and Cerebrovascular Disease in Relation to Depressive Symptomatology in Individuals With Subjective Cognitive
Decline
M. Zapater-Fajarí, P. Diaz-Galvan, N. Cedres, Therese Rydberg Sterner, Lina Rydén, Simona Sacuiu, Margda Waern, Anna Zettergren, Henrik Zetterberg, Kaj Blennow, Silke Kern, V. Hidalgo, A. Salvador, E. Westman, Ingmar Skoog, D. Ferreira
Journals of Gerontology Series a-Biological Sciences and Medical Sciences - 2024 -
Human herpesvirus 6A and axonal injury before the clinical onset of multiple
sclerosis.
Viktor Grut, Martin Biström, Jonatan Salzer, Pernilla Stridh, Daniel Jons, Rasmus Gustafsson, Anna Fogdell-Hahn, Jesse Huang, Julia Butt, Anna Lindam, Lucia Alonso-Magdalena, Tomas Bergström, Ingrid Kockum, Tim Waterboer, Tomas Olsson, Henrik Zetterberg, Kaj Blennow, Oluf Andersen, Staffan Nilsson, Peter Sundström
Brain : a journal of neurology - 2024 -
Elevated CSF GAP-43 is associated with accelerated tau accumulation and spread in Alzheimer's
disease.
Nicolai Franzmeier, Amir Dehsarvi, Anna Steward, Davina Biel, Anna Dewenter, Sebastian Niclas Roemer, Fabian Wagner, Mattes Groß, Matthias Brendel, Alexis Moscoso Rial, Prithvi Arunachalam, Kaj Blennow, Henrik Zetterberg, Michael Ewers, Michael Schöll
Nature communications - 2024 -
Biomarkers for neurodegeneration impact cognitive function: a longitudinal 1-year case–control study of patients with bipolar disorder and healthy control
individuals
Ulla Knorr, Anja Hviid Simonsen, Henrik Zetterberg, Kaj Blennow, Mira Willkan, Julie Forman, Kamilla Miskowiak, Steen Gregers Hasselbalch, Lars Vedel Kessing
International Journal of Bipolar Disorders - 2024 -
The Immune Signature of CSF in Multiple Sclerosis with and without Oligoclonal Bands: A Machine Learning Approach to Proximity Extension Assay
Analysis
Lorenzo Gaetani, Giovanni Bellomo, Elena Di Sabatino, Silvia Sperandei, Andrea Mancini, Kaj Blennow, Henrik Zetterberg, Lucilla Parnetti, Massimiliano Di Filippo
International Journal of Molecular Sciences - 2024 -
Comparison of immunoassay- with mass spectrometry-derived p-tau quantification for the detection of Alzheimer’s disease
pathology
Joseph Therriault, Marcel S. Woo, Gemma Salvadó, Johan Gobom, Thomas Karikari, Shorena Janelidze, Stijn Servaes, Nesrine Rahmouni, Cécile Tissot, Nicholas J. Ashton, Andréa Lessa Benedet, Laia Montoliu-Gaya, Arthur C. Macedo, Firoza Z. Lussier, Jenna Stevenson, Paolo Vitali, Manuel A. Friese, Gassan Massarweh, Jean Paul Soucy, Tharick A. Pascoal, Erik Stomrud, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Serge Gauthier, Henrik Zetterberg, Oskar Hansson, Kaj Blennow, Pedro Rosa-Neto
Molecular Neurodegeneration - 2024 -
Association of region-specific hippocampal reduction of neurogranin with inflammasome proteins in post mortem brains of Alzheimer's
disease
Regina T. Vontell, Ryan Gober, Julian Dallmeier, Daniel Brzostowicki, Ayled Barreda, Kaj Blennow, Henrik Zetterberg, Hlin Kvartsberg, Sakir Humayun Gultekin, Juan Pablo de Rivero Vaccari, Helen M. Bramlett, W. Dalton Dietrich, Robert W. Keane, David A. Davis, Tatjana Rundek, Xiaoyan Sun
ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS - 2024 -
Brain magnetic resonance imaging findings six months after critical COVID-19: A prospective cohort
study.
Henriikka Ollila, Janne Pihlajamaa, Juha Martola, Linda Kuusela, Kaj Blennow, Henrik Zetterberg, Viljami Salmela, Laura Hokkanen, Marjaana Tiainen, Johanna Hästbacka
Journal of critical care - 2024 -
CSF p-tau205: a biomarker of tau pathology in Alzheimer's
disease.
Juan Lantero Rodriguez, Laia Montoliu-Gaya, Andréa Lessa Benedet, Agathe Vrillon, Julien Dumurgier, Emmanuel Cognat, Wagner Scheeren Brum, Nesrine Rahmouni, Jenna Stevenson, Stijn Servaes, Joseph Therriault, Bruno Becker, Gunnar Brinkmalm, Anniina Snellman, Hanna Huber, Hlin Kvartsberg, Nicholas J. Ashton, Henrik Zetterberg, Claire Paquet, Pedro Rosa-Neto, Kaj Blennow
Acta neuropathologica - 2024 -
Elevated CSF angiopoietin-2 correlates with blood-brain barrier leakiness and markers of neuronal injury in early Alzheimer's
disease
Carol Van Hulle, Selvi Ince, Ozioma C. Okonkwo, Barbara B. Bendlin, Sterling C. Johnson, Cynthia M. Carlsson, Sanjay Asthana, Seth Love, Kaj Blennow, Henrik Zetterberg, J. Scott Miners
TRANSLATIONAL PSYCHIATRY - 2024 -
Associations between recall of proper names in story recall and CSF amyloid and tau in adults without cognitive
impairment.
Madeline R Hale, Rebecca Langhough, Lianlian Du, Bruce P Hermann, Carol A Van Hulle, Margherita Carboni, Gwendlyn Kollmorgen, Kristin E Basche, Davide Bruno, Leah Sanson-Miles, Erin M Jonaitis, Nathaniel A Chin, Ozioma C Okonkwo, Barbara B Bendlin, Cynthia M Carlsson, Henrik Zetterberg, Kaj Blennow, Tobey J Betthauser, Sterling C Johnson, Kimberly D Mueller
Neurobiology of aging - 2024 -
Astrocyte reactivity influences the association of amyloid-β and tau biomarkers in preclinical Alzheimer's
disease.
Tharick Pascoal, Bruna Bellaver, Guilherme Povala, Pamela Ferreira, João Pedro Ferrari-Souza, Douglas Leffa, Firoza Lussier, Andréa Lessa Benedet, Nicholas J. Ashton, Gallen Triana-Baltzerz, Hartmuth Kolbzh, Cèile Tissot, Joseph Therriault, Stijn Servaes, Jenna Stevenson, Nesrine Rahmouni, Oscar Lopez, Dana Tudorascu, Victor Villemagne, Milos Ikonomovic, Serge Gauthier, Eduardo Zimmer, Henrik Zetterberg, Kaj Blennow, Howard Aizenstein, William Klunk, Beth Snitz, Pauline Maki, Rebecca Thurston, Ann Cohen, Mary Ganguli, Thomas Karikari, Pedro Rosa-Neto
Research square - 2023 -
Diagnostic accuracy of the plasma ALZpath pTau217 immunoassay to identify Alzheimer's disease
pathology.
Nicholas J. Ashton, Wagner Scheeren Brum, Guglielmo Di Molfetta, Andréa Lessa Benedet, Burak Arslan, Erin Jonatis, Rebecca E Langhough, Karly Cody, Rachael Wilson, Cynthia M Carlsson, Eugeen Vanmechelen, Laia Montoliu-Gaya, Juan Lantero Rodriguez, Nesrine Rahmouni, Cecile Tissot, Jenna Stevenson, Stijn Servaes, Joseph Therriault, Tharick Pascoal, Alberto Lleó, Daniel Alcolea, Juan Fortea, Pedro Rosa-Neto, Sterling Johnson, Andreas Jeromin, Kaj Blennow, Henrik Zetterberg
medRxiv : the preprint server for health sciences - 2023 -
Brain-derived Tau for Monitoring Brain Injury in Acute Ischemic
Stroke.
Naomi Vlegels, Fernando Gonzalez-Ortiz, Nicoló Luca Knuth, Nada Khalifeh, Benno Gesierich, Franziska Müller, Philipp Müller, Matthias Klein, Konstantinos Dimitriadis, Nicolai Franzmeier, Thomas Liebig, Marco Duering, Paul Reidler, Martin Dichgans, Thomas Karikari, Kaj Blennow, Steffen Tiedt
medRxiv : the preprint server for health sciences - 2023 -
Association between ventricular CSF biomarkers and outcome after shunt surgery in idiopathic normal pressure
hydrocephalus.
Rebecca Grønning, Anna Jeppsson, Per Hellström, Katarina Laurell, Dan Farahmand, Henrik Zetterberg, Kaj Blennow, Carsten Wikkelsö, Mats Tullberg
Fluids and Barriers of the CNS - 2023 -
Menopause hormone therapy significantly alters pathophysiological biomarkers of Alzheimer's
disease
D. Herman, V. Andrea, L. Pablo, L. Simone, Andréa Lessa Benedet, Nicholas J. Ashton, C. Enrica, Henrik Zetterberg, Kaj Blennow, V. Eugeen, H. Harald
Alzheimers & Dementia - 2023 -
SCRN1: A cerebrospinal fluid biomarker correlating with tau in Alzheimer's
disease
Sophia Weiner, Mathias Sauer, Gunnar Brinkmalm, Julius Constantinescu, Radu Constantinescu, Bárbara Fernandes Gomes, Bruno Becker, Bengt Nellgård, Keti Dalla, Douglas Galasko, Henrik Zetterberg, Kaj Blennow, Johan Gobom
Alzheimer's and Dementia - 2023 -
α-Synuclein seed amplification assay as a diagnostic tool for parkinsonian
disorders.
Bárbara Fernandes Gomes, Carly M Farris, Yihua Ma, Luis Concha-Marambio, Russ Lebovitz, Bengt Nellgård, Keti Dalla, Julius Constantinescu, Radu Constantinescu, Johan Gobom, Ulf Andreasson, Henrik Zetterberg, Kaj Blennow
Parkinsonism & related disorders - 2023 -
Cerebrospinal Fluid Panel of Synaptic Proteins in Cerebral Amyloid Angiopathy and Alzheimer's
Disease
E. van den Berg, Johanna Nilsson, I. Kersten, Gunnar Brinkmalm, A. M. de Kort, C. J. M. Klijn, Fhbm Schreuder, L. Jakel, Johan Gobom, E. Portelius, Henrik Zetterberg, Ann Brinkmalm, Kaj Blennow, H. B. Kuiperij, M. M. Verbeek
Journal of Alzheimers Disease - 2023 -
Prevalence and Clinical Implications of a β-Amyloid-Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer
Disease.
Pontus Erickson, Joel Simrén, Wagner Scheeren Brum, Gilda E Ennis, Gwendlyn Kollmorgen, Ivonne Suridjan, Rebecca Langhough, Erin M Jonaitis, Carol A Van Hulle, Tobey J Betthauser, Cynthia M Carlsson, Sanjay Asthana, Nicholas J. Ashton, Sterling C Johnson, Leslie M Shaw, Kaj Blennow, Ulf Andreasson, Barbara B Bendlin, Henrik Zetterberg
JAMA neurology - 2023 -
Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non-Alzheimer's disease
pathophysiology
A. Delvenne, Johan Gobom, B. Tijms, I. Bos, L. M. Reus, V. Dobricic, M. Ten Kate, F. Verhey, I. Ramakers, P. Scheltens, C. E. Teunissen, R. Vandenberghe, J. Schaeverbeke, S. Gabel, J. Popp, G. Peyratout, P. Martinez-Lage, M. Tainta, M. Tsolaki, Y. Freund-Levi, S. Lovestone, J. Streffer, F. Barkhof, L. Bertram, Kaj Blennow, Henrik Zetterberg, P. J. Visser, S. J. B. Vos
Alzheimers & Dementia - 2023 -
A comparison of diagnostic performance of word-list and story recall tests for biomarker-determined Alzheimer's
disease
D. Bruno, A. J. Zinkunegi, G. Kollmorgen, M. Carboni, N. Wild, C. Carlsson, B. Bendlin, O. Okonkwo, N. Chin, B. P. Hermann, S. Asthana, Kaj Blennow, R. Langhough, S. C. Johnson, N. Pomara, Henrik Zetterberg, K. D. Mueller
Journal of Clinical and Experimental Neuropsychology - 2023 -
Altered brain dopamine metabolism is a trait marker for bipolar
disorder
Erik Pålsson, Carl Sellgren, Aurimantas Pelanis, Henrik Zetterberg, Kaj Blennow, Mikael Landén
Biomarkers in Neuropsychiatry - 2023 -
Differential effects of sleep on brain structure and metabolism at the preclinical stages of
AD
L. Stankeviciute, C. Falcon, G. Operto, M. Garcia, M. Shekari, A. Iranzo, A. Ninerola-Baizan, A. Perissinotti, C. Minguillon, K. Fauria, J. L. Molinuevo, Henrik Zetterberg, Kaj Blennow, M. Suarez-Calvet, R. Cacciaglia, J. D. Gispert, O. Grau-Rivera
Alzheimers & Dementia - 2023 -
Analytical and clinical validation of a blood progranulin ELISA in frontotemporal
dementias
Francisco J Meda, Joel Simrén, B. Borroni, V. Cantoni, S. Archetti, G. Biasiotto, Ulf Andreasson, Kaj Blennow, Hlin Kvartsberg, Henrik Zetterberg
Clinical Chemistry and Laboratory Medicine - 2023 -
Longitudinal blood biomarker trajectories in preclinical Alzheimer's
disease
Y. Yakoub, Nicholas J. Ashton, C. Strikwerda-Brown, Laia Montoliu-Gaya, Thomas Karikari, Przemyslaw R. Kac, Fernando Gonzalez-Ortiz, J. Gallego-Rudolf, P. F. Meyer, F. St-Onge, Michael Schöll, J. P. Soucy, J. C. S. Breitner, Henrik Zetterberg, Kaj Blennow, J. Poirier, S. Villeneuve
Alzheimers & Dementia - 2023 -
Intrathecal kappa free light chain synthesis is associated with worse prognosis in relapsing-remitting multiple
sclerosis
Igal Rosenstein, Markus Axelsson, Lenka Novakova, Clas Malmeström, Kaj Blennow, Henrik Zetterberg, Jan Lycke
Journal of Neurology - 2023 -
Levels of Alzheimer's disease blood biomarkers are altered after food intake-A pilot intervention study in healthy
adults
Hanna Huber, Nicholas J. Ashton, A. Schieren, Laia Montoliu-Gaya, Guglielmo Di Molfetta, Wagner Scheeren Brum, Juan Lantero Rodriguez, Lana Grötschel, B. Stoffel-Wagner, M. Coenen, L. Weinhold, M. Schmid, Kaj Blennow, P. Stehle, Henrik Zetterberg, M. C. Simon
Alzheimers & Dementia - 2023 -
Plasma and CSF concentrations of N-terminal tau fragments associate with in vivo neurofibrillary tangle
burden
Juan Lantero Rodriguez, C. Tissot, Anniina Snellman, S. Servaes, Andréa Lessa Benedet, N. Rahmouni, Laia Montoliu-Gaya, J. Therriault, Wagner Scheeren Brum, J. Stevenson, F. Z. Lussier, G. Bezgin, A. C. Macedo, M. Chamoun, S. S. Mathotaarachi, T. A. Pascoal, Nicholas J. Ashton, Henrik Zetterberg, P. R. Neto, Kaj Blennow
Alzheimers & Dementia - 2023 -
Preanalytical stability of plasma/serum brain-derived
tau
Fernando Gonzalez-Ortiz, A. Dias, M. Turton, R. Magalhaes, Przemyslaw R. Kac, M. Correia, P. Harrison, Henrik Zetterberg, L. F. Maia, Kaj Blennow, Thomas Karikari
Alzheimers & Dementia - 2023 -
Alzheimer Disease Blood Biomarkers in Patients With Out-of-Hospital Cardiac
Arrest
Nicholas J. Ashton, M. Moseby-Knappe, Andréa Lessa Benedet, Lana Grötschel, Juan Lantero Rodriguez, Thomas Karikari, C. Hassager, M. P. Wise, P. Stammet, J. Kjaergaard, H. Friberg, N. Nielsen, T. Cronberg, Henrik Zetterberg, Kaj Blennow
Jama Neurology - 2023 -
Test-retest variability of plasma biomarkers in Alzheimer's disease and its effects on clinical prediction
models
N. C. Cullen, S. Janelidze, N. Mattsson-Carlgren, S. Palmqvist, T. Bittner, I. Suridjan, A. Jethwa, G. Kollmorgen, W. S. Brum, Henrik Zetterberg, Kaj Blennow, E. Stomrud, O. Hansson
Alzheimers & Dementia - 2023 -
An accurate fully automated panel of plasma biomarkers for Alzheimer's
disease
S. Palmqvist, E. Stomrud, N. Cullen, S. Janelidze, E. Manuilova, A. Jethwa, T. Bittner, U. Eichenlaub, I. Suridjan, G. Kollmorgen, M. Riepe, C. A. F. von Arnim, H. Tumani, K. Hager, F. Heidenreich, N. Mattsson-Carlgren, Henrik Zetterberg, Kaj Blennow, O. Hansson
Alzheimers & Dementia - 2023 -
Astrocyte biomarkers GFAP and YKL-40 mediate early Alzheimer's disease
progression.
Wiesje Pelkmans, Mahnaz Shekari, Anna Brugulat-Serrat, Gonzalo Sánchez-Benavides, Carolina Minguillón, Karine Fauria, Jose Luis Molinuevo, Oriol Grau-Rivera, Armand González Escalante, Gwendlyn Kollmorgen, Margherita Carboni, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Marc Suarez-Calvet, Juan Domingo Gispert
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2023 -
Neurodegenerative biomarkers outperform neuroinflammatory biomarkers in amyotrophic lateral
sclerosis.
Ulf Kläppe, Stefan Sennfält, Anikó Lovik, Anja Finn, Ulrika Bofaisal, Henrik Zetterberg, Kaj Blennow, Fredrik Piehl, Ivan Kmezic, Rayomand Press, Kristin Samuelsson, Anna Månberg, Fang Fang, Caroline Ingre
Amyotrophic lateral sclerosis & frontotemporal degeneration - 2023 -
A novel ultrasensitive assay for plasma p-tau217: performance in individuals with subjective cognitive decline and early Alzheimer's
disease.
Fernando Gonzalez-Ortiz, Pamela C L Ferreira, Armand Gonzalez, Laia Montoliu-Gaya, Paula Ortiz-Romero, Przemyslaw R. Kac, Michael Turton, Hlin Kvartsberg, Nicholas J. Ashton, Henrik Zetterberg, Peter Harrison, Bruna Bellaver, Guilherme Povala, Victor L Villemagne, Tharick A Pascoal, Mary Ganguli, Anne D Cohen, Carolina Miguillon, Jose Contador, Marc Suarez-Calvet, Thomas Karikari, Kaj Blennow
medRxiv : the preprint server for health sciences - 2023 -
Sex differences in blood biomarkers and cognitive performance in individuals with autosomal dominant Alzheimer's
disease
C. Vila-Castelar, Y. H. Chen, S. Langella, F. Lopera, Henrik Zetterberg, O. Hansson, J. L. Dage, S. Janelidzde, Y. Su, K. W. Chen, C. P. McDowell, J. E. Martinez, L. Ramirez-Gomez, G. Garcia, D. Aguillon, A. Baena, M. Giraldo-Chica, H. D. Protas, V. Ghisays, S. Rios-Romenets, P. N. Tariot, Kaj Blennow, E. M. Reiman, Y. T. Quiroz
Alzheimers & Dementia - 2023 -
Blood-brain barrier integrity impacts the use of plasma amyloid-beta as a proxy of brain amyloid-beta
pathology
B. Bellaver, A. Puig-Pijoan, J. P. Ferrari-Souza, D. T. Leffa, F. Z. Lussier, P. C. L. Ferreira, C. Tissot, G. Povala, J. Therriault, Andréa Lessa Benedet, Nicholas J. Ashton, S. Servaes, M. Chamoun, J. Stevenson, N. Rahmouni, M. Vermeiren, A. C. Macedo, A. Fernandez-Lebrero, G. Garcia-Escobar, I. Navalpotro-Gomez, O. Lopez, D. L. Tudorascu, A. Cohen, V. L. Villemagne, W. E. Klunk, S. Gauthier, E. R. Zimmer, Thomas Karikari, Kaj Blennow, Henrik Zetterberg, M. Suarez-Calvet, P. Rosa-Neto, T. A. Pascoal
Alzheimers & Dementia - 2023 -
Plasma neurofilament light in behavioural variant frontotemporal dementia compared to mood and psychotic
disorders
D. Eratne, M. Kang, C. Malpas, S. Simpson-Yap, C. Lewis, C. Dang, J. Grewal, A. Coe, H. Dobson, M. Keem, W. H. Chiu, T. Kalincik, S. Ooi, D. Darby, A. Brodtmann, O. Hansson, S. Janelidze, Kaj Blennow, Henrik Zetterberg, A. Walker, O. Dean, M. Berk, C. Wannan, C. Pantelis, S. M. Loi, M. Walterfang, S. F. Berkovic, A. F. Santillo, D. Velakoulis, N. D. Study Grp Mi
Australian and New Zealand Journal of Psychiatry - 2023 -
Mediterranean diet is associated with lower white matter lesion volume in Mediterranean cities and lower cerebrospinal fluid Aβ42 in non-Mediterranean cities in the EPAD LCS
cohort.
Sarah Gregory, Kaj Blennow, Craig W Ritchie, Oliver M Shannon, Emma J Stevenson, Graciela Muniz-Terrera
Neurobiology of aging - 2023 -
Optimal combinations of CSF biomarkers for predicting cognitive decline and clinical conversion in cognitively unimpaired participants and mild cognitive impairment patients: A multi-cohort
study
G. Salvado, V. Larsson, K. A. Cody, N. C. Cullen, E. M. Jonaitis, E. Stomrud, G. Kollmorgen, N. Wild, S. Palmqvist, S. Janelidze, N. Mattsson-Carlgren, Henrik Zetterberg, Kaj Blennow, S. C. Johnson, R. Ossenkoppele, O. Hansson
Alzheimers & Dementia - 2023 -
Neurofilament light oligomers in neurodegenerative diseases: quantification by homogeneous immunoassay in cerebrospinal
fluid
Francisco J Meda, Kathryn Knowles, Imogen J. Swift, Aitana Sogorb-Esteve, Jonathan D. Rohrer, Anna Dittrich, Ingmar Skoog, Silke Kern, Bruno Becker, Kaj Blennow, Ulf Andreasson, Hlin Kvartsberg, Henrik Zetterberg
BMJ NEUROLOGY OPEN - 2023 -
Sex, age, and regional differences in CHRM1 and CHRM3 genes expression levels in the human brain biopsies: potential targets for Alzheimer's disease-related sleep
disturbances.
Cristina Sanfilippo, Loretta Giuliano, Paola Castrogiovanni, Rosa Imbesi, Martina Ulivieri, Francesco Fazio, Kaj Blennow, Henrik Zetterberg, Michelino Di Rosa
Current neuropharmacology - 2023 -
APOEε4 potentiates amyloid β effects on longitudinal tau
pathology
J. P. Ferrari-Souza, B. Bellaver, P. C. L. Ferreira, Andréa Lessa Benedet, G. Povala, F. Z. Lussier, D. T. Leffa, J. Therriault, C. Tissot, C. Soares, Y. T. Wang, M. Chamoun, S. Servaes, A. C. Macedo, M. Vermeiren, G. Bezgin, M. S. Kang, J. Stevenson, N. Rahmouni, V. Pallen, N. M. Poltronetti, A. Cohen, O. L. Lopez, W. E. Klunk, J. P. Soucy, S. Gauthier, D. O. Souza, G. Triana-Baltzer, Z. S. Saad, H. C. Kolb, Thomas Karikari, V. L. Villemagne, D. L. Tudorascu, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, E. R. Zimmer, P. Rosa-Neto, T. A. Pascoal
Nature Aging - 2023 -
Investigating New Applications of a Photoswitchable Fluorescent Norbornadiene as a Multifunctional Probe for Delineation of Amyloid Plaque
Polymorphism.
Ambra Dreos, Junyue Ge, Francisco Najera, Behabitu Ergette Tebikachew, Ezequiel Perez-Inestrosa, Kasper Moth-Poulsen, Kaj Blennow, Henrik Zetterberg, Jörg Hanrieder
ACS sensors - 2023 -
Longitudinal interplay between subclinical atherosclerosis, cardiovascular risk factors, and cerebral glucose metabolism in midlife: results from the PESA prospective cohort
study
C. Tristao-Pereira, V. Fuster, B. Oliva, A. Moreno-Arciniegas, I. Garcia-Lunar, C. Perez-Herreras, Michael Schöll, M. Suárez-Calvet, M. A. Moro, A. Garcia-Alvarez, A. Fernandez-Ortiz, J. Sanchez-Gonzalez, Henrik Zetterberg, Kaj Blennow, B. Ibanez, J. Gispert, M. Cortes-Canteli
Lancet Healthy Longevity - 2023 -
New mass spectrometry method to simultaneously quantify several tau species in
blood
Laia Montoliu-Gaya, Kaj Blennow
NATURE AGING - 2023 -
Blood beta-synuclein is related to amyloid PET positivity in memory clinic
patients
P. Oeckl, M. Bluma, M. Bucci, S. Halbgebauer, K. Chiotis, A. Sandebring-Matton, Nicholas J. Ashton, Guglielmo Di Molfetta, Lana Grötschel, M. Kivipelto, Kaj Blennow, Henrik Zetterberg, I. Savitcheva, A. Nordberg, M. Otto
Alzheimers & Dementia - 2023 -
Higher CSF/serum free-T4 ratio is associated with improvement of quality of life during treatment with
L-thyroxine
A. Funkquist, B. Wandt, Kaj Blennow, Henrik Zetterberg, Johan Svensson, P. Bjellerup, Y. Freund-Levi, S. Sjoberg
Journal of Neuroendocrinology - 2023 -
Plasma biomarkers identify older adults at risk of Alzheimer's disease and related dementias in a real-world population-based
cohort
P. C. L. Ferreira, Y. J. Zhang, B. Snitz, C. C. H. Chang, B. Bellaver, E. Jacobsen, M. I. Kamboh, Henrik Zetterberg, Kaj Blennow, T. A. Pascoal, V. L. Villemagne, M. Ganguli, Thomas Karikari
Alzheimers & Dementia - 2023 -
Circulating Brain-Injury Markers After Surgery for
Craniosynostosis
Isak Michaëlsson, Thomas Skoglund, Tobias Hallén, Robert Olsson, Giovanni Maltese, Peter Tarnow, Madiha Bhatti Söfteland, Henrik Zetterberg, Kaj Blennow, Lars Kölby
World Neurosurgery - 2023 -
Neuropathology-based APOE genetic risk score better quantifies Alzheimer's
risk
Y. Deming, E. Vasiljevic, A. Morrow, J. C. Miao, C. Van Hulle, E. Jonaitis, Y. Ma, V. Whitenack, G. Kollmorgen, N. Wild, I. Suridjan, L. M. Shaw, S. Asthana, C. M. Carlsson, S. C. Johnson, Henrik Zetterberg, Kaj Blennow, B. B. Bendlin, Q. S. Lu, C. D. Engelman
Alzheimers & Dementia - 2023 -
Assessing the commutability of candidate reference materials for the harmonization of neurofilament light measurements in
blood
Ulf Andreasson, Johan Gobom, V. Delatour, G. Auclair, Y. Noam, S. P. Lee, J. S. Wen, A. Jeromin, Burak Arslan, A. Maceski, E. Willemse, Henrik Zetterberg, J. Kuhle, Kaj Blennow
Clinical Chemistry and Laboratory Medicine - 2023 -
Clinical performance and robustness evaluation of plasma amyloid-beta(42/40)
prescreening
C. Rabe, T. Bittner, A. Jethwa, I. Suridjan, E. Manuilova, M. Friesenhahn, E. Stomrud, Henrik Zetterberg, Kaj Blennow, O. Hansson
Alzheimers & Dementia - 2023 -
Plasma and CSF biomarkers in a memory clinic: Head-to-head comparison of phosphorylated tau
immunoassays
Nicholas J. Ashton, A. Puig-Pijoan, M. Mila-Aloma, A. Fernandez-Lebrero, G. Garcia-Escobar, Fernando Gonzalez-Ortiz, Przemyslaw R. Kac, Wagner Scheeren Brum, Andréa Lessa Benedet, Juan Lantero Rodriguez, T. A. Day, J. Vanbrabant, E. Stoops, E. Vanmechelen, G. Triana-Baltzer, S. Moughadam, H. Kolb, P. Ortiz-Romero, Thomas Karikari, C. Minguillon, J. J. H. Sanchez, I. Navalpotro-Gomez, O. Grau-Rivera, R. M. Manero, V. Puente-Periz, R. de la Torre, J. Roquer, J. L. Dage, Henrik Zetterberg, Kaj Blennow, M. Suarez-Calvet
Alzheimers & Dementia - 2023 -
High polygenic risk score for exceptional longevity is associated with a healthy metabolic
profile
M. Revelas, A. Thalamuthu, Anna Zettergren, C. Oldmeadow, Jenna Najar, Nazib Seidu, N. J. Armstrong, C. Riveros, J. B. Kwok, P. R. Schofield, J. N. Trollor, Margda Waern, M. J. Wright, Henrik Zetterberg, D. Ames, Kaj Blennow, H. Brodaty, R. J. Scott, Ingmar Skoog, J. R. Attia, P. S. Sachdev, K. A. Mather
Geroscience - 2023 -
Mechanisms behind changes of neurodegeneration biomarkers in plasma induced by sleep
deprivation.
Per Kristian Eide, Aslan Lashkarivand, Are Hugo Pripp, Lars Magnus Valnes, Markus Hovd, Geir Ringstad, Kaj Blennow, Henrik Zetterberg
Brain communications - 2023 -
Cross-Sectional Associations of CSF Tau Levels With Rey's AVLT: A Recency Ratio
Study
D. Bruno, A. J. Zinkunegi, N. Pomara, Henrik Zetterberg, Kaj Blennow, R. L. Koscik, C. Carlsson, B. Bendlin, O. Okonkwo, B. P. Hermann, S. C. Johnson, K. D. Mueller
Neuropsychology - 2023 -
Combined Evidence for a Long-Term, Clinical Slowing Effect of Multinutrient Intervention in Prodromal Alzheimer's Disease: Post-Hoc Analysis of 3-Year Data from the LipiDiDiet
Trial
S. B. Hendrix, H. Soininen, A. Solomon, P. J. Visser, A. M. J. van Hees, D. S. Counotte, J. Nicodemus-Johnson, S. P. Dickson, Kaj Blennow, M. Kivipelto, T. Hartmann
Jpad-Journal of Prevention of Alzheimers Disease - 2023 -
Longitudinal changes in Alzheimer's-related plasma biomarkers and brain
amyloid
M. Bilgel, Y. An, K. A. Walker, A. R. Moghekar, Nicholas J. Ashton, Przemyslaw R. Kac, Thomas Karikari, Kaj Blennow, Henrik Zetterberg, B. M. Jedynak, M. Thambisetty, L. Ferrucci, S. M. Resnick
Alzheimers & Dementia - 2023 -
Molecules of senescent glial cells differentiate Alzheimer's disease from
ageing
L. B. Dai, F. Gao, Q. Wang, X. Y. Lv, Z. Z. Cheng, Y. Wu, X. L. Chai, Henrik Zetterberg, Kaj Blennow, A. I. Levey, J. Shi, Y. Shen
Journal of Neurology Neurosurgery and Psychiatry - 2023 -
The amyloid-beta pathway in Alzheimer's disease: a plain language
summary
H. Hampel, Y. Hu, J. Hardy, Kaj Blennow, C. S. P. Chen, G. Perry, S. H. Kim, V. L. Villemagne, P. Aisen, M. Vendruscolo, T. Iwatsubo, C. L. Masters, M. Cho, L. Lannfelt, J. L. Cummings, A. Vergallo
Neurodegenerative Disease Management - 2023 -
Two Phase 3 Trials of Gantenerumab in Early Alzheimer's
Disease
Randall J. Bateman, Janice Smith, Michael C. Donohue, Paul Delmar, Rachid Abbas, Stephen Salloway, Jakub Wojtowicz, Kaj Blennow, Tobias Bittner, Sandra E. Black, Gregory Klein, Mercè Boada, Timo Grimmer, Akira Tamaoka, Richard J. Perry, R. Scott Turner, David Watson, Michael Woodward, Angeliki Thanasopoulou, Christopher Lane, Monika Baudler, Nick C. Fox, Jeffrey L. Cummings, Paulo Fontoura, Rachelle S. Doody
New England Journal of Medicine - 2023 -
Diagnostic Performance of Cerebrospinal Fluid Neurofilament Light Chain and Soluble Amyloid-β Protein Precursor β in the Subcortical Small Vessel Type of
Dementia.
Elin Axelsson, Petronella Kettunen, Maria Bjerke, Sindre Rolstad, Henrik Zetterberg, Kaj Blennow, Anders Wallin, Johan Svensson
Journal of Alzheimer's disease : JAD - 2023 -
Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer's
disease.
Kaja Nordengen, Bjørn-Eivind Kirsebom, Grit Richter, Lene Pålhaugen, Berglind Gísladóttir, Nikias Siafarikas, Arne Nakling, Arvid Rongve, Geir Bråthen, Gøril Rolfseng Grøntvedt, Fernando Gonzalez-Ortiz, Knut Waterloo, Kulbhushan Sharma, Thomas Karikari, Eleonora M Vromen, Betty M Tijms, Pieter J Visser, Per Selnes, Milicia G Kramberger, Bengt Winblad, Kaj Blennow, Tormod Fladby
Journal of neuroinflammation - 2023 -
Clinical stage and plasma neurofilament concentration in adults with Friedreich
ataxia
Magnus Johnsson, Henrik Zetterberg, Kaj Blennow, Christopher Lindberg
Heliyon - 2023 -
Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic
functioning.
Alexander Neumann, Olena Ohlei, Fahri Küçükali, Isabelle J Bos, Jigyasha Timsina, Stephanie Vos, Dmitry Prokopenko, Betty M Tijms, Ulf Andreasson, Kaj Blennow, Rik Vandenberghe, Philip Scheltens, Charlotte E Teunissen, Sebastiaan Engelborghs, Giovanni B Frisoni, Oliver Blin, Jill C Richardson, Régis Bordet, Alberto Lleó, Daniel Alcolea, Julius Popp, Thomas W Marsh, Priyanka Gorijala, Christopher Clark, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Richard J B Dobson, Cristina Legido-Quigley, Christine Van Broeckhoven, Rudolph E Tanzi, Mara Ten Kate, Christina M Lill, Frederik Barkhof, Carlos Cruchaga, Simon Lovestone, Johannes Streffer, Henrik Zetterberg, Pieter Jelle Visser, Kristel Sleegers, Lars Bertram
Genome medicine - 2023 -
Association of Choroid Plexus Volume With Serum Biomarkers, Clinical Features, and Disease Severity in Patients With Frontotemporal Lobar Degeneration
Spectrum
M. Assogna, E. Premi, S. Gazzina, A. Benussi, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, R. Gasparotti, A. Padovani, E. Tadayon, S. Romanella, G. Sprugnoli, A. Pascual-Leone, F. Di Lorenzo, G. Koch, B. Borroni, E. Santarnecchi
NEUROLOGY - 2023 -
Tracking reactive astrogliosis in autosomal dominant and sporadic Alzheimer's disease with multi-modal PET and plasma
GFAP
K. Chiotis, C. Johansson, E. Rodriguez-Vieitez, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, C. Graff, A. Nordberg
Molecular Neurodegeneration - 2023 -
Next-generation proteomics technologies in Alzheimer's disease: from clinical research to routine
diagnostics
Sophia Weiner, Kaj Blennow, Henrik Zetterberg, Johan Gobom
Expert Review of Proteomics - 2023 -
CSF metabolites associated with biomarkers of Alzheimer's disease
pathology
R. C. Dong, Q. S. Lu, H. Kang, I. Suridjan, G. Kollmorgen, N. Wild, Y. Deming, C. A. Van Hulle, R. M. Anderson, Henrik Zetterberg, Kaj Blennow, C. M. Carlsson, S. Asthana, S. C. Johnson, C. D. Engelman
Frontiers in Aging Neuroscience - 2023 -
A two-step workflow based on plasma p-tau217 to screen for amyloid β positivity with further confirmatory testing only in uncertain
cases
Wagner Scheeren Brum, N. C. Cullen, S. Janelidze, Nicholas J. Ashton, E. R. Zimmer, J. Therriault, Andréa Lessa Benedet, N. Rahmouni, C. Tissot, J. Stevenson, S. Servaes, G. Triana-Baltzer, H. C. Kolb, S. Palmqvist, E. Stomrud, P. Rosa-Neto, Kaj Blennow, O. Hansson
Nature Aging - 2023 -
Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04
subtypes.
Yann Le Guen, Guo Luo, Aditya Ambati, Vincent Damotte, Iris Jansen, Eric Yu, Aude Nicolas, Itziar de Rojas, Thiago Peixoto Leal, Akinori Miyashita, Céline Bellenguez, Michelle Mulan Lian, Kayenat Parveen, Takashi Morizono, Hyeonseul Park, Benjamin Grenier-Boley, Tatsuhiko Naito, Fahri Küçükali, Seth D Talyansky, Selina Maria Yogeshwar, Vicente Sempere, Wataru Satake, Victoria Alvarez, Beatrice Arosio, Michael E Belloy, Luisa Benussi, Anne Boland, Barbara Borroni, María J Bullido, Paolo Caffarra, Jordi Clarimon, Antonio Daniele, Daniel Darling, Stéphanie Debette, Jean-François Deleuze, Martin Dichgans, Carole Dufouil, Emmanuel During, Emrah Düzel, Daniela Galimberti, Guillermo Garcia-Ribas, José María García-Alberca, Pablo García-González, Vilmantas Giedraitis, Oliver Goldhardt, Caroline Graff, Edna Grünblatt, Olivier Hanon, Lucrezia Hausner, Stefanie Heilmann-Heimbach, Henne Holstege, Jakub Hort, Yoo Jin Jung, Deckert Jürgen, Silke Kern, Teemu Kuulasmaa, Kun Ho Lee, Ling Lin, Carlo Masullo, Patrizia Mecocci, Shima Mehrabian, Alexandre de Mendonça, Mercè Boada, Pablo Mir, Susanne Moebus, Fermin Moreno, Benedetta Nacmias, Gael Nicolas, Shumpei Niida, Børge G Nordestgaard, Goran Papenberg, Janne Papma, Lucilla Parnetti, Florence Pasquier, Pau Pastor, Oliver Peters, Yolande A L Pijnenburg, Gerard Piñol-Ripoll, Julius Popp, Laura Molina Porcel, Raquel Puerta, Jordi Pérez-Tur, Innocenzo Rainero, Inez Ramakers, Luis M Real, Steffi Riedel-Heller, Eloy Rodriguez-Rodriguez, Owen A Ross, Luis Jose Royo, Dan Rujescu, Nikolaos Scarmeas, Philip Scheltens, Norbert Scherbaum, Anja Schneider, Davide Seripa, Ingmar Skoog, Vincenzo Solfrizzi, Gianfranco Spalletta, Alessio Squassina, John van Swieten, Raquel Sánchez-Valle, Eng-King Tan, Thomas Tegos, Charlotte Teunissen, Jesper Qvist Thomassen, Lucio Tremolizzo, Martin Vyhnalek, Frans Verhey, Margda Waern, Jens Wiltfang, Jing Zhang, Henrik Zetterberg, Kaj Blennow, Zihuai He, Julie Williams, Philippe Amouyel, Frank Jessen, Patrick G Kehoe, Ole A Andreassen, Cornelia Van Duin, Magda Tsolaki, Pascual Sánchez-Juan, Ruth Frikke-Schmidt, Kristel Sleegers, Tatsushi Toda, Anna Zettergren, Martin Ingelsson, Yukinori Okada, Giacomina Rossi, Mikko Hiltunen, Jungsoo Gim, Kouichi Ozaki, Rebecca Sims, Jia Nee Foo, Wiesje van der Flier, Takeshi Ikeuchi, Alfredo Ramirez, Ignacio Mata, Agustín Ruiz, Ziv Gan-Or, Jean-Charles Lambert, Michael D Greicius, Emmanuel Mignot
Proceedings of the National Academy of Sciences of the United States of America - 2023 -
Effect of Pathway-Specific Polygenic Risk Scores for Alzheimer's Disease (AD) on Rate of Change in Cognitive Function and AD-Related Biomarkers Among Asymptomatic
Individuals.
Yuexuan Xu, Eva Vasiljevic, Yuetiva K Deming, Erin M Jonaitis, Rebecca L Koscik, Carol A Van Hulle, Qiongshi Lu, Margherita Carboni, Gwendlyn Kollmorgen, Norbert Wild, Cynthia M Carlsson, Sterling C Johnson, Henrik Zetterberg, Kaj Blennow, Corinne D Engelman
Journal of Alzheimer's disease : JAD - 2023 -
Plasma neurofilament light admission levels and development of axonal pathology in mild traumatic brain
injury
I. Hossain, M. Mohammadian, H. R. Maanpaeae, R. S. K. Takala, O. Tenovuo, M. van Gils, P. Hutchinson, D. K. Menon, V. F. Newcombe, J. Tallus, J. Hirvonen, T. Roine, T. Kurki, Kaj Blennow, Henrik Zetterberg, J. P. Posti
BMC Neurology - 2023 -
Hypotension during transsphenoidal pituitary surgery associated with increase in plasma levels of brain injury
markers.
Martinn Thorsson, Tobias Hallén, Daniel S Olsson, Kaj Blennow, Henrik Zetterberg, Gudmundur Johannsson, Thomas Skoglund, Jonatan Oras
Acta anaesthesiologica Scandinavica - 2023 -
Profiling of plasma biomarkers in the context of memory assessment in a tertiary memory
clinic
M. Bucci, M. Bluma, I. Savitcheva, Nicholas J. Ashton, K. Chiotis, A. Matton, M. Kivipelto, Guglielmo Di Molfetta, Kaj Blennow, Henrik Zetterberg, A. Nordberg
Translational Psychiatry - 2023 -
Associations of neuroinflammatory IL-6 and IL-8 with brain atrophy, memory decline, and core AD biomarkers-in cognitively unimpaired older
adults
E. Capogna, L. O. Watne, O. Sorensen, C. J. Guichelaar, A. V. Idland, N. B. Halaas, Kaj Blennow, Henrik Zetterberg, K. B. Walhovd, A. M. Fjell, D. Vidal-Pineiro
Brain, behavior, and immunity - 2023 -
Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical
Trials
P. C. L. Ferreira, J. P. Ferrari-Souza, C. Tissot, B. Bellaver, D. T. Leffa, F. Lussier, G. Povala, J. Therriault, Andréa Lessa Benedet, Nicholas J. Ashton, A. D. Cohen, O. L. Lopez, D. L. Tudorascu, W. E. Klunk, J. P. Soucy, S. Gauthier, V. Villemagne, Henrik Zetterberg, Kaj Blennow, P. Rosa-Neto, E. R. Zimmer, Thomas Karikari, T. A. Pascoal, Neuroimaging Alzheimers Dis
NEUROLOGY - 2023 -
Associations of CSF PDGFR & beta; With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic
Changes
C. Cicognola, N. Mattsson-Carlgren, D. van Westen, Henrik Zetterberg, Kaj Blennow, S. Palmqvist, K. Ahmadi, O. Strandberg, E. Stomrud, S. Janelidze, O. Hansson
NEUROLOGY - 2023 -
Plasma neurofilament light chain level is not a biomarker of Charcot-Marie-Tooth disease progression: Results of 3-year follow-up
study
S. Setlere, A. Grosmane, N. Kurjane, L. Gailite, D. Rots, Kaj Blennow, Henrik Zetterberg, V. Kenina
European Journal of Neurology - 2023 -
Astrocyte reactivity influences amyloid-beta effects on tau pathology in preclinical Alzheimer's
disease
B. Bellaver, G. Povala, P. C. L. Ferreira, J. P. Ferrari-Souza, D. T. Leffa, F. Z. Lussier, Andréa Lessa Benedet, Nicholas J. Ashton, G. Triana-Baltzer, H. C. Kolb, C. Tissot, J. Therriault, S. Servaes, J. Stevenson, N. Rahmouni, O. L. Lopez, D. L. Tudorascu, V. L. Villemagne, M. D. Ikonomovic, S. Gauthier, E. R. Zimmer, Henrik Zetterberg, Kaj Blennow, H. J. Aizenstein, W. E. Klunk, B. E. Snitz, P. Maki, R. C. Thurston, A. D. Cohen, M. Ganguli, Thomas Karikari, P. Rosa-Neto, T. A. Pascoal
Nature Medicine - 2023 -
Blood biomarkers for Alzheimer's disease in clinical practice and
trials
O. Hansson, Kaj Blennow, Henrik Zetterberg, J. Dage
Nature Aging - 2023 -
Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's
disease.
Shorena Janelidze, Divya Bali, Nicholas J. Ashton, Nicolas R Barthélemy, Jeroen Vanbrabant, Erik Stoops, Eugeen Vanmechelen, Yingxin He, Anna Orduña Dolado, Gallen Triana-Baltzer, Michael J Pontecorvo, Henrik Zetterberg, Hartmuth Kolb, Manu Vandijck, Kaj Blennow, Randall J Bateman, Oskar Hansson
Brain : a journal of neurology - 2023 -
Large-scale proteome and metabolome analysis of CSF implicates altered glucose and carbon metabolism and succinylcarnitine in Alzheimer's
disease
D. J. Panyard, J. McKetney, Y. K. Deming, A. R. Morrow, G. E. Ennis, E. M. Jonaitis, C. A. Van Hulle, C. R. Yang, Y. J. Sung, M. Ali, G. Kollmorgen, I. Suridjan, A. Bayfield, B. B. Bendlin, Henrik Zetterberg, Kaj Blennow, C. Cruchaga, C. M. Carlsson, S. C. Johnson, S. Asthana, J. J. Coon, C. D. Engelman
Alzheimers & Dementia - 2023 -
Tau in cerebrospinal fluid induces neuronal hyperexcitability and alters hippocampal theta
oscillations
J. Brown, Elena Camporesi, Juan Lantero Rodriguez, M. Olsson, A. L. C. Wang, B. Medem, Henrik Zetterberg, Kaj Blennow, Thomas Karikari, M. Wall, E. Hill
Acta Neuropathologica Communications - 2023 -
Prevalence and Characteristics Associated With Post-COVID-19 Condition Among Nonhospitalized Adolescents and Young
Adults
J. Selvakumar, L. B. Havdal, M. Drevvatne, E. M. Brodwall, L. Lund Berven, T. Stiansen-Sonerud, G. Einvik, T. M. Leegaard, T. Tjade, A. E. Michelsen, T. E. Mollnes, F. Lund-Johansen, T. Holmoy, Henrik Zetterberg, Kaj Blennow, C. X. Sandler, E. Cvejic, A. R. Lloyd, V. B. B. Wyller
JAMA Network Open - 2023 -
Liver-Specific Polygenic Risk Score Is Associated with Alzheimer's Disease
Diagnosis
D. J. Panyard, Y. K. Deming, B. F. Darst, C. A. Van Hulle, Henrik Zetterberg, Kaj Blennow, G. Kollmorgen, I. Suridjan, C. M. Carlsson, S. C. Johnson, S. Asthana, C. D. Engelman, Q. S. Lu
Journal of Alzheimers Disease - 2023 -
Clinical performance and head-to-head comparison of CSF p-tau235 with p-tau181, p-tau217 and p-tau231 in two memory clinic
cohorts
Juan Lantero Rodriguez, A. Vrillon, A. Fernandez-Lebrero, P. Ortiz-Romero, Anniina Snellman, Laia Montoliu-Gaya, Wagner Scheeren Brum, E. Cognat, J. Dumurgier, A. Puig-Pijoan, I. Navalpotro-Gomez, G. Garcia-Escobar, Thomas Karikari, E. Vanmechelen, Nicholas J. Ashton, Henrik Zetterberg, M. Suarez-Calvet, C. Paquet, Kaj Blennow
Alzheimers Research & Therapy - 2023 -
Hippocampal GFAP-positive astrocyte responses to amyloid and tau
pathologies.
Marco Antônio De Bastiani, Bruna Bellaver, Wagner Scheeren Brum, Debora G Souza, Pamela C L Ferreira, Andreia S Rocha, Guilherme Povala, João Pedro Ferrari-Souza, Andréa Lessa Benedet, Nicholas J. Ashton, Thomas Karikari, Henrik Zetterberg, Kaj Blennow, Pedro Rosa-Neto, Tharick A Pascoal, Eduardo R Zimmer
Brain, behavior, and immunity - 2023 -
Tetramodal Chemical Imaging Delineates the Lipid-Amyloid Peptide Interplay at Single Plaques in Transgenic Alzheimer?s Disease
Models
Junyue Ge, Srinivas Koutarapu, Durga Jha, Maciej Dulewicz, Henrik Zetterberg, Kaj Blennow, Jörg Hanrieder
Analytical Chemistry - 2023 -
Subtle Differences in Cognition in 70-Year-Olds with Elevated Cerebrospinal Fluid Neurofilament Light and Neurogranin: A H70 Cross-Sectional
Study
Maya Arvidsson Rådestig, Johan Skoog, Henrik Zetterberg, Tobias Skillbäck, Anna Zettergren, Therese Rydberg Sterner, Madeleine Mellqvist Fässberg, Simona Sacuiu, Margda Waern, Hanna Wetterberg, Kaj Blennow, Ingmar Skoog, Silke Kern
Journal of Alzheimers Disease - 2023 -
Neurogranin in Alzheimer's disease and ageing: A human post-mortem
study
T. Saunders, C. Gunn, Kaj Blennow, Hlin Kvartsberg, Henrik Zetterberg, S. D. Shenkin, S. R. Cox, I. J. Deary, C. Smith, D. King, T. Spires-Jones
Neurobiology of Disease - 2023 -
Plasma GFAP in presymptomatic and symptomatic familial Alzheimer's disease: a longitudinal cohort
study.
Antoinette O'Connor, Emily Abel, Andréa Lessa Benedet, Teresa Poole, Nicholas J. Ashton, Philip Simon John Weston, Amanda J Heslegrave, Natalie Ryan, Suzie Barker, James M Polke, Kaj Blennow, Henrik Zetterberg, Nick C Fox
Journal of neurology, neurosurgery, and psychiatry - 2023 -
Concordance of Alzheimer's Disease-Related Biomarkers Between Intraventricular and Lumbar Cerebrospinal Fluid in Idiopathic Normal Pressure
Hydrocephalus.
Heikki Lukkarinen, Aleksi Vanninen, Ina Tesseur, Darrel Pemberton, Peter Van Der Ark, Tarja Kokkola, Sanna-Kaisa Herukka, Tuomas Rauramaa, Mikko Hiltunen, Kaj Blennow, Henrik Zetterberg, Ville Leinonen
Journal of Alzheimer's disease : JAD - 2023 -
Sevoflurane dose and postoperative delirium: a prospective cohort
analysis.
Jennifer Taylor, Thomas Payne, Cameron Casey, David Kunkel, Maggie Parker, Cameron Rivera, Henrik Zetterberg, Kaj Blennow, Robert A Pearce, Richard C Lennertz, Tim McCulloch, Amy Gaskell, Robert D Sanders
British journal of anaesthesia - 2023 -
Plasma p-tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer's
disease.
David Aguillon, Stephanie Langella, Yinghua Chen, Justin S Sanchez, Yi Su, Clara Vila-Castelar, Daniel Vasquez, Henrik Zetterberg, Oskar Hansson, Jeffrey L Dage, Shorena Janelidze, Kewei Chen, Joshua T Fox-Fuller, Paula Aduen, Jairo E Martinez, Gloria Garcia, Ana Baena, Claudia Guzman, Keith A Johnson, Reisa A Sperling, Kaj Blennow, Eric M Reiman, Francisco Lopera, Yakeel T Quiroz
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2023 -
Blood biomarkers and neurodegeneration in individuals exposed to repetitive head
impacts.
Charles Bernick, Guogen Shan, Aaron Ritter, Nicholas J. Ashton, Kaj Blennow, Juan Lantero Rodriguez, Anniina Snellman, Henrik Zetterberg
Alzheimer's research & therapy - 2023 -
Neurofilament light chain on intensive care admission is an independent predictor of mortality in COVID-19: a prospective multicenter
study.
Theodor Sievert, Ingrid Didriksson, Martin Spångfors, Gisela Lilja, Kaj Blennow, Henrik Zetterberg, Attila Frigyesi, Hans Friberg
Intensive care medicine experimental - 2023 -
Reference Data for Attentional, Executive, Linguistic, and Visual Processing Tests Obtained from Cognitively Healthy Individuals with Normal Alzheimer's Disease Cerebrospinal Fluid Biomarker
Levels.
David López-Martos, Anna Brugulat-Serrat, Alba Cañas-Martínez, Lidia Canals-Gispert, Paula Marne, Nina Gramunt, Marc Suárez-Calvet, Marta Milà-Alomà, Carolina Minguillon, Karine Fauria, Henrik Zetterberg, Kaj Blennow, Juan Domingo Gispert, José Luis Molinuevo, Oriol Grau-Rivera, Gonzalo Sánchez-Benavides
Journal of Alzheimer's disease : JAD - 2023 -
The potential clinical value of plasma biomarkers in Alzheimer's
disease.
Kaj Blennow, Douglas Galasko, Robert Perneczky, Frances-Catherine Quevenco, Wiesje M van der Flier, Akin Akinwonmi, Margherita Carboni, Alexander Jethwa, Ivonne Suridjan, Henrik Zetterberg
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2023 -
Alzheimer's disease biomarker profiling in a memory clinic cohort without common
comorbidities.
Makrina Daniilidou, Francesca Eroli, Vilma Alanko, Julen Goikolea, Maria Latorre-Leal, Patricia Rodriguez-Rodriguez, William J Griffiths, Yuqin Wang, Manuela Pacciarini, Ann Brinkmalm-Westman, Henrik Zetterberg, Kaj Blennow, Anna Rosenberg, Nenad Bogdanovic, Bengt Winblad, Miia Kivipelto, Delphine Ibghi, Angel Cedazo-Minguez, Silvia Maioli, Anna Matton
Brain communications - 2023 -
Association of Serum Brain-Derived Tau With Clinical Outcome and Longitudinal Change in Patients With Severe Traumatic Brain
Injury.
Fernando Gonzalez-Ortiz, Maciej Dulewicz, Nicholas J. Ashton, Przemyslaw R. Kac, Henrik Zetterberg, Emma Andersson, Yara Yakoub, Jörg Hanrieder, Michael Turton, Peter Harrison, Bengt Nellgård, Thomas Karikari, Kaj Blennow
JAMA network open - 2023 -
Second-generation Elecsys cerebrospinal fluid immunoassays aid diagnosis of early Alzheimer's
disease.
Kaj Blennow, Erik Stomrud, Henrik Zetterberg, Niels Borlinghaus, Veronika Corradini, Ekaterina Manuilova, Laura Müller-Hübner, Frances-Catherine Quevenco, Sandra Rutz, Oskar Hansson
Clinical chemistry and laboratory medicine - 2023 -
Prognostic performance of blood neurofilament light chain protein in hospitalized COVID-19 patients without major central nervous system manifestations: an individual participant data
meta-analysis.
Ahmed Abdelhak, Lorenzo Barba, Michele Romoli, Pascal Benkert, Francesco Conversi, Lucio D'Anna, Ruturaj R Masvekar, Bibiana Bielekova, Mercedes Prudencio, Leonard Petrucelli, James F Meschia, Young Erben, Roberto Furlan, Rebecca De Lorenzo, Alessandra Mandelli, Raoul Sutter, Lisa Hert, Varenka Epple, Damiano Marastoni, Johann Sellner, Petra Steinacker, Anne Hege Aamodt, Lars Heggelund, Anne Margarita Dyrhol-Riise, Johan Virhammar, David Fällmar, Elham Rostami, Eva Kumlien, Kaj Blennow, Henrik Zetterberg, Hayrettin Tumani, Simona Sacco, Ari J Green, Markus Otto, Jens Kuhle, Raffaele Ornello, Matteo Foschi, Samir Abu-Rumeileh
Journal of neurology - 2023 -
The genetic regulation of protein expression in cerebrospinal
fluid.
Oskar Hansson, Atul Kumar, Shorena Janelidze, Erik Stomrud, Philip S Insel, Kaj Blennow, Henrik Zetterberg, Eric Fauman, Åsa K Hedman, Michael W Nagle, Christopher D Whelan, Denis Baird, Anders Mälarstig, Niklas Mattsson-Carlgren
EMBO molecular medicine - 2023 -
Association of Chronic Kidney Disease With Plasma NfL and Other Biomarkers of Neurodegeneration: The H70 Birth Cohort Study in
Gothenburg.
Anna Dittrich, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Anna Zettergren, Joel Simrén, Tobias Skillbäck, Sara Shams, Alejandra Machado, Eric Westman, Michael Schöll, Ingmar Skoog, Silke Kern
Neurology - 2023 -
Serum and cerebrospinal fluid brain damage markers neurofilament light and glial fibrillary acidic protein correlate with tick-borne encephalitis disease severity-a multicentre study on Lithuanian and Swedish
patients.
Malin Veje, Vytautas Griška, Jolita Pakalnienė, Auksė Mickienė, Daniel Bremell, Henrik Zetterberg, Kaj Blennow, Lars Lindquist, Marie Studahl
European journal of neurology - 2023 -
Low-density granulocytes are related to shorter pregnancy duration but not to interferon alpha protein blood levels in systemic lupus
erythematosus.
Agnes Torell, Marit Stockfelt, Gunilla Larsson, Kaj Blennow, Henrik Zetterberg, Dag Leonard, Lars Rönnblom, Muna Saleh, Christopher Sjöwall, Helena Strevens, Andreas Jönsen, Anders A Bengtsson, Estelle Trysberg, Maria Majcuk Sennström, Agneta Zickert, Elisabet Svenungsson, Iva Gunnarsson, Karin Christenson, Johan Bylund, Bo Jacobsson, Anna Rudin, Anna-Carin Lundell
Arthritis research & therapy - 2023 -
Correlative Chemical Imaging Identifies Amyloid Peptide Signatures of Neuritic Plaques and Dystrophy in Human Sporadic Alzheimer's
Disease.
Srinivas Koutarapu, Junyue Ge, Durga Jha, Kaj Blennow, Henrik Zetterberg, Tammaryn Lashley, Wojciech Michno, Jörg Hanrieder
Brain connectivity - 2023 -
Cerebrospinal fluid neurofilament light predicts longitudinal diagnostic change in patients with psychiatric and neurodegenerative
disorders.
Matthew Jy Kang, Dhamidhu Eratne, Hannah Dobson, Charles B Malpas, Michael Keem, Courtney Lewis, Jasleen Grewal, Vivian Tsoukra, Christa Dang, Ramon Mocellin, Tomas Kalincik, Alexander F Santillo, Henrik Zetterberg, Kaj Blennow, Christiane Stehmann, Shiji Varghese, Qiao-Xin Li, Colin L Masters, Steven Collins, Samuel F Berkovic, Andrew Evans, Wendy Kelso, Sarah Farrand, Samantha M Loi, Mark Walterfang, Dennis Velakoulis
Acta neuropsychiatrica - 2023 -
Plasma Biomarkers of Alzheimer Disease in Women With and Without
HIV
Xuantao Li, Recai Yucel, Helene Clervius, Kundun Kamalakar, Henrik Zetterberg, Kaj Blennow, Jinbing Zhang, Adaora Adimora, Lauren Collins, Margaret Fischl, Seble Kassaye, Pauline Maki, Eric Seaberg, Anjali Sharma, David Vance, Deborah Gustafson
JAMA network open - 2023 -
The Relationships between Cerebrospinal Fluid Glial (CXCL12, CX3CL, YKL-40) and Synaptic Biomarkers (Ng, NPTXR) in Early Alzheimer's
Disease.
Agnieszka Kulczyńska-Przybik, Maciej Dulewicz, Julia Doroszkiewicz, Renata Borawska, Agnieszka Słowik, Henrik Zetterberg, Jörg Hanrieder, Kaj Blennow, Barbara Mroczko
International journal of molecular sciences - 2023 -
Serum IGFBP-1 Concentration as a Predictor of Outcome after
Ischemic Stroke—A Prospective Observational
Study
Daniel Åberg, Gustaf Gadd, Katarina Jood, Petra Redfors, Tara M Stanne, Jörgen Isgaard, Kaj Blennow, Henrik Zetterberg, Christina Jern, N David Åberg, Johan Svensson
International Journal of Molecular Sciences - 2023 -
A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer's disease using an indwelling CSF
catheter.
Kelsie M LaBarbera, Yvette I Sheline, Nicholas J Izzo, Carla M Yuede, Lora Waybright, Raymond Yurko, Hannah M Edwards, Woodrow D Gardiner, Kaj Blennow, Henrik Zetterberg, Anne Börjesson-Hanson, Roger Morgan, Charles S Davis, Robert J Guttendorf, Lon S Schneider, Steven DeKosky, Harry LeVine, Michael Grundman, Anthony O Caggiano, John R Cirrito, Susan M Catalano, Mary E Hamby
Translational neurodegeneration - 2023 -
Association of CSF GAP-43 With the Rate of Cognitive Decline and Progression to Dementia in Amyloid-Positive
Individuals.
Annika Öhrfelt, Andréa Lessa Benedet, Nicholas J. Ashton, Hlin Kvartsberg, Manu Vandijck, Michael W Weiner, John Q Trojanowski, Leslie M Shaw, Henrik Zetterberg, Kaj Blennow
Neurology - 2023 -
Plasma biomarkers for neurodegenerative disorders: ready for prime
time?
W. G. Balogun, Henrik Zetterberg, Kaj Blennow, Thomas Karikari
Current Opinion in Psychiatry - 2023 -
Characterization of the contactin 5 protein and its risk-associated polymorphic variant throughout the Alzheimer's disease
spectrum
M. T. Dauar, A. Labonté, C. Picard, J. Miron, P. Rosa-Neto, Henrik Zetterberg, Kaj Blennow, S. Villeneuve, J. Poirier
Alzheimer's and Dementia - 2023 -
Buntanetap, a Novel Translational Inhibitor of Multiple Neurotoxic Proteins, Proves to Be Safe and Promising in Both Alzheimer’s and Parkinson’s
Patients
C. Fang, P. Hernandez, K. Liow, E. Damiano, Henrik Zetterberg, Kaj Blennow, D. Feng, M. Chen, M. Maccecchini
Journal of Prevention of Alzheimer's Disease - 2023 -
The multifaceted role of neurofilament light chain protein in non-primary neurological
diseases.
Samir Abu-Rumeileh, Ahmed Abdelhak, Matteo Foschi, Lucio D'Anna, Michele Russo, Petra Steinacker, Jens Kuhle, Hayrettin Tumani, Kaj Blennow, Markus Otto
Brain : a journal of neurology - 2023 -
Tau-PET is superior to phospho-tau when predicting cognitive decline in symptomatic AD
patients.
Ruben Smith, Nicholas C Cullen, Alexa Pichet Binette, Antoine Leuzy, Kaj Blennow, Henrik Zetterberg, Gregory Klein, Edilio Borroni, Rik Ossenkoppele, Shorena Janelidze, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Erik Stomrud, Oskar Hansson
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2023 -
Blood-based biomarkers for Alzheimer's disease: Current state and future use in a transformed global healthcare
landscape.
Harald Hampel, Yan Hu, Jeffrey Cummings, Soeren Mattke, Takeshi Iwatsubo, Akinori Nakamura, Bruno Vellas, Sid O'Bryant, Leslie M Shaw, Min Cho, Richard Batrla, Andrea Vergallo, Kaj Blennow, Jeffrey Dage, Suzanne E Schindler
Neuron - 2023 -
Dementia prevention in memory clinics: recommendations from the European task force for brain health
services
G. B. Frisoni, D. Altomare, F. Ribaldi, N. Villain, C. Brayne, N. Mukadam, M. Abramowicz, F. Barkhof, M. Berthier, M. Bieler-Aeschlimann, Kaj Blennow, A. B. Guevara, E. Carrera, G. Chetelat, C. Csajka, J. F. Demonet, A. Dodich, V. Garibotto, J. Georges, S. Hurst, F. Jessen, M. Kivipelto, D. J. Llewellyn, L. McWhirter, R. Milne, C. Minguillon, C. Miniussi, J. LuisMolinuevo, P. M. Nilsson, A. Noyce, J. M. Ranson, O. Grau-Rivera, J. M. Schott, A. Solomon, R. Stephen, W. van der Flier, C. van Duijn, B. Vellas, L. N. C. Visser, J. L. Cummings, P. Scheltens, C. Ritchie, B. Dubois
Lancet Regional Health-Europe - 2023 -
Comparison of CSF and plasma NfL and pNfH for Alzheimer’s disease diagnosis: a memory clinic
study
Agathe Vrillon, Nicholas J. Ashton, Thomas Karikari, Karl Götze, Emmanuel Cognat, Julien Dumurgier, Matthieu Lilamand, Henrik Zetterberg, Kaj Blennow, Claire Paquet
Journal of Neurology - 2023 -
Harmonization and standardization of biofluid-based biomarker measurements for AT(N) classification in Alzheimer's
disease
C. Giangrande, V. Delatour, Ulf Andreasson, Kaj Blennow, Johan Gobom, Henrik Zetterberg
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring - 2023 -
Neuropsychiatric Symptoms and Microglial Activation in Patients with Alzheimer
Disease
Cristiano Schaffer Aguzzoli, Pâmela C.L. Ferreira, Guilherme Povala, João Pedro Ferrari-Souza, Bruna Bellaver, Carolina Soares Katz, Hussein Zalzale, Firoza Z. Lussier, Francieli Rohden, Sarah Abbas, Douglas T. Leffa, Marina Scop Medeiros, Joseph Therriault, Andréa Lessa Benedet, Cécile Tissot, Stijn Servaes, Nesrine Rahmouni, Arthur Cassa Macedo, Gleb Bezgin, Min Su Kang, Jenna Stevenson, Vanessa Pallen, Ann Cohen, Oscar L. Lopez, Dana L. Tudorascu, William E. Klunk, Victor L. Villemagne, Jean Paul Soucy, Eduardo R. Zimmer, Lucas P. Schilling, Thomas Karikari, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Serge Gauthier, Victor Valcour, Bruce L. Miller, Pedro Rosa-Neto, Tharick A. Pascoal
JAMA network open - 2023 -
Effect of Pathway-specific Polygenic Risk Scores for Alzheimer's Disease (AD) on Rate of Change in Cognitive Function and AD-related Biomarkers among Asymptomatic
Individuals.
Yuexuan Xu, Eva Vasiljevic, Yuetiva K Deming, Erin M Jonaitis, Rebecca L Koscik, Carol A Van Hulle, Qiongshi Lu, Margherita Carboni, Gwendlyn Kollmorgen, Norbert Wild, Cynthia M Carlsson, Sterling C Johnson, Henrik Zetterberg, Kaj Blennow, Corinne D Engelman
medRxiv : the preprint server for health sciences - 2023 -
The taxonomy of subjective cognitive decline: proposal and first clinical evidence from the Geneva memory clinic
cohort.
Federica Ribaldi, Rafael Palomo, Daniele Altomare, Max Scheffler, Frederic Assal, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Marc Abramowicz, Valentina Garibotto, Christian Chicherio, Giovanni B Frisoni
Research square - 2023 -
Neuroimaging of tissue microstructure as a marker of neurodegeneration in the AT(N) framework: defining abnormal neurodegeneration and improving prediction of clinical
status
R. L. Gallagher, R. L. Koscik, J. F. Moody, N. M. Vogt, N. Adluru, S. R. Kecskemeti, C. A. Van Hulle, N. A. Chin, S. Asthana, G. Kollmorgen, I. Suridjan, C. M. Carlsson, S. C. Johnson, III Dean, Henrik Zetterberg, Kaj Blennow, A. L. Alexander, B. B. Bendlin
Alzheimer's Research & Therapy - 2023 -
Polygenic risk scores for Alzheimer's disease in relation to cognitive change: A representative sample from the general population followed over 16
years.
Jenna Najar, Valgeir Thorvaldsson, Silke Kern, Johan Skoog, Margda Waern, Henrik Zetterberg, Kaj Blennow, Ingmar Skoog, Anna Zettergren
Neurobiology of Disease - 2023 -
Revealing the combined roles of Aβ and tau in Alzheimer's disease via a pathophysiological activity
decoder.
Lazaro M Sanchez-Rodriguez, Gleb Bezgin, Felix Carbonell, Joseph Therriault, Jaime Fernandez-Arias, Stijn Servaes, Nesrine Rahmouni, Cecile Tissot, Jenna Stevenson, Thomas Karikari, Nicholas J. Ashton, Andréa Lessa Benedet, Henrik Zetterberg, Kaj Blennow, Gallen Triana-Baltzer, Hartmuth C Kolb, Pedro Rosa-Neto, Yasser Iturria-Medina
bioRxiv : the preprint server for biology - 2023 -
Plasma p-tau212: antemortem diagnostic performance and prediction of autopsy verification of Alzheimer's disease
neuropathology.
Przemyslaw R. Kac, Fernándo González-Ortiz, Andreja Emeršič, Maciej Dulewicz, Srinivas Koutarapu, Michael Turton, Yang An, Denis Smirnov, Agnieszka Kulczyńska-Przybik, Vijay Varma, Nicholas J. Ashton, Laia Montoliu-Gaya, Elena Camporesi, Izabela Winkel, Bogusław Paradowski, Abhay Moghekar, Juan C Troncoso, Gunnar Brinkmalm, Susan M Resnick, Barbara Mroczko, Hlin Kvartsberg, Milica Gregorič Kramberger, Jörg Hanrieder, Saša Čučnik, Peter Harrison, Henrik Zetterberg, Piotr Lewczuk, Madhav Thambisetty, Uroš Rot, Douglas Galasko, Kaj Blennow, Thomas Karikari
medRxiv : the preprint server for health sciences - 2023 -
A Modified Mediterranean Ketogenic Diet mitigates modifiable risk factors of Alzheimer's Disease: a serum and CSF-based metabolic
analysis.
Annalise Schweickart, Richa Batra, Bryan J Neth, Cameron Martino, Liat Shenhav, Anru R Zhang, Pixu Shi, Naama Karu, Kevin Huynh, Peter J Meikle, Leyla Schimmel, Amanda Hazel Dilmore, Kaj Blennow, Henrik Zetterberg, Colette Blach, Pieter C Dorrestein, Rob Knight, Suzanne Craft, Rima Kaddurah-Daouk, Jan Krumsiek
medRxiv : the preprint server for health sciences - 2023 -
Sex and Education Modify the Association Between Subjective Cognitive Decline and Amyloid
Pathology.
Corey J Bolton, Omair A Khan, Dandan Liu, Sydney Wilhoite, Logan Dumitrescu, Amalia Peterson, Kaj Blennow, Henrik Zetterberg, Timothy J Hohman, Angela L Jefferson, Katherine A Gifford
medRxiv : the preprint server for health sciences - 2023 -
Cross-sectional and longitudinal evaluation of plasma glial fibrillary acidic protein to detect and predict clinical syndromes of Alzheimer's
disease
M. Ally, M. A. Sugarman, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Thomas Karikari, H. J. Aparicio, B. Frank, Y. Tripodis, B. Martin, J. N. Palmisano, E. G. Steinberg, I. Simkin, L. A. Farrer, G. R. Jun, K. W. Turk, A. E. Budson, M. K. O'Connor, R. Au, L. E. Goldstein, N. W. Kowall, R. Killiany, R. A. Stern, T. D. Stein, A. C. McKee, W. Q. Qiu, J. Mez, M. L. Alosco
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring - 2023 -
Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk
scores.
Itziar de Rojas, Sonia Moreno-Grau, Niccolo Tesi, Benjamin Grenier-Boley, Victor Andrade, Iris E Jansen, Nancy L Pedersen, Najada Stringa, Anna Zettergren, Isabel Hernández, Laura Montrreal, Carmen Antúnez, Anna Antonell, Rick M Tankard, Joshua C Bis, Rebecca Sims, Céline Bellenguez, Inés Quintela, Antonio González-Perez, Miguel Calero, Emilio Franco-Macías, Juan Macías, Rafael Blesa, Laura Cervera-Carles, Manuel Menéndez-González, Ana Frank-García, Jose Luís Royo, Fermin Moreno, Raquel Huerto Vilas, Miquel Baquero, Mónica Diez-Fairen, Carmen Lage, Sebastián García-Madrona, Pablo García-González, Emilio Alarcón-Martín, Sergi Valero, Oscar Sotolongo-Grau, Abbe Ullgren, Adam C Naj, Afina W Lemstra, Alba Benaque, Alba Pérez-Cordón, Alberto Benussi, Alberto Rábano, Alessandro Padovani, Alessio Squassina, Alexandre de Mendonça, Alfonso Arias Pastor, Almar A L Kok, Alun Meggy, Ana Belén Pastor, Ana Espinosa, Anaïs Corma-Gómez, Angel Martín Montes, Ángela Sanabria, Anita L DeStefano, Anja Schneider, Annakaisa Haapasalo, Anne Kinhult Ståhlbom, Anne Tybjærg-Hansen, Annette M Hartmann, Annika Spottke, Arturo Corbatón-Anchuelo, Arvid Rongve, Barbara Borroni, Beatrice Arosio, Benedetta Nacmias, Børge G Nordestgaard, Brian W Kunkle, Camille Charbonnier, Carla Abdelnour, Carlo Masullo, Carmen Martínez Rodríguez, Carmen Muñoz-Fernandez, Carole Dufouil, Caroline Graff, Catarina B Ferreira, Caterina Chillotti, Chandra A Reynolds, Chiara Fenoglio, Christine Van Broeckhoven, Christopher Clark, Claudia Pisanu, Claudia L Satizabal, Clive Holmes, Dolores Buiza-Rueda, Dag Aarsland, Dan Rujescu, Daniel Alcolea, Daniela Galimberti, David Wallon, Davide Seripa, Edna Grünblatt, Efthimios Dardiotis, Emrah Düzel, Elio Scarpini, Elisa Conti, Elisa Rubino, Ellen Gelpi, Eloy Rodriguez-Rodriguez, Emmanuelle Duron, Eric Boerwinkle, Evelyn Ferri, Fabrizio Tagliavini, Fahri Küçükali, Florence Pasquier, Florentino Sanchez-Garcia, Francesca Mangialasche, Frank Jessen, Gaël Nicolas, Geir Selbæk, Gemma Ortega, Geneviève Chêne, Georgios Hadjigeorgiou, Giacomina Rossi, Gianfranco Spalletta, Giorgio Giaccone, Giulia Grande, Giuliano Binetti, Goran Papenberg, Harald Hampel, Henri Bailly, Henrik Zetterberg, Hilkka Soininen, Ida K Karlsson, Ignacio Alvarez, Ildebrando Appollonio, Ina Giegling, Ingmar Skoog, Ingvild Saltvedt, Innocenzo Rainero, Irene Rosas Allende, Jakub Hort, Janine Diehl-Schmid, Jasper Van Dongen, Jean-Sebastien Vidal, Jenni Lehtisalo, Jens Wiltfang, Jesper Qvist Thomassen, Johannes Kornhuber, Jonathan L Haines, Jonathan Vogelgsang, Juan A Pineda, Juan Fortea, Julius Popp, Jürgen Deckert, Katharina Buerger, Kevin Morgan, Klaus Fließbach, Kristel Sleegers, Laura Molina-Porcel, Lena Kilander, Leonie Weinhold, Lindsay A Farrer, Li-San Wang, Luca Kleineidam, Lucia Farotti, Lucilla Parnetti, Lucio Tremolizzo, Lucrezia Hausner, Luisa Benussi, Lutz Froelich, M Arfan Ikram, M Candida Deniz-Naranjo, Magda Tsolaki, Maitée Rosende-Roca, Malin Löwenmark, Marc Hulsman, Marco Spallazzi, Margaret A Pericak-Vance, Margaret Esiri, María Bernal Sánchez-Arjona, Maria Carolina Dalmasso, María Teresa Martínez-Larrad, Marina Arcaro, Markus M Nöthen, Marta Fernández-Fuertes, Martin Dichgans, Martin Ingelsson, Martin J Herrmann, Martin Scherer, Martin Vyhnalek, Mary H Kosmidis, Mary Yannakoulia, Matthias Schmid, Michael Ewers, Michael T Heneka, Michael Wagner, Michela Scamosci, Miia Kivipelto, Mikko Hiltunen, Miren Zulaica, Montserrat Alegret, Myriam Fornage, Natalia Roberto, Natasja M van Schoor, Nazib M Seidu, Nerisa Banaj, Nicola J Armstrong, Nikolaos Scarmeas, Norbert Scherbaum, Oliver Goldhardt, Oliver Hanon, Oliver Peters, Olivia Anna Skrobot, Olivier Quenez, Ondrej Lerch, Paola Bossù, Paolo Caffarra, Paolo Dionigi Rossi, Paraskevi Sakka, Patrizia Mecocci, Per Hoffmann, Peter A Holmans, Peter Fischer, Peter Riederer, Qiong Yang, Rachel Marshall, Rajesh N Kalaria, Richard Mayeux, Rik Vandenberghe, Roberta Cecchetti, Roberta Ghidoni, Ruth Frikke-Schmidt, Sandro Sorbi, Sara Hägg, Sebastiaan Engelborghs, Seppo Helisalmi, Sigrid Botne Sando, Silke Kern, Silvana Archetti, Silvia Boschi, Silvia Fostinelli, Silvia Gil, Silvia Mendoza, Simon Mead, Simona Ciccone, Srdjan Djurovic, Stefanie Heilmann-Heimbach, Steffi Riedel-Heller, Teemu Kuulasmaa, Teodoro Del Ser, Thibaud Lebouvier, Thomas Polak, Tiia Ngandu, Timo Grimmer, Valentina Bessi, Valentina Escott-Price, Vilmantas Giedraitis, Vincent Deramecourt, Wolfgang Maier, Xueqiu Jian, Yolande A L Pijnenburg, Patrick Gavin Kehoe, Guillermo Garcia-Ribas, Pascual Sánchez-Juan, Pau Pastor, Jordi Pérez-Tur, Gerard Piñol-Ripoll, Adolfo Lopez de Munain, Jose María García-Alberca, María J Bullido, Victoria Álvarez, Alberto Lleó, Luis M Real, Pablo Mir, Miguel Medina, Philip Scheltens, Henne Holstege, Marta Marquié, María Eugenia Sáez, Ángel Carracedo, Philippe Amouyel, Gerard D Schellenberg, Julie Williams, Sudha Seshadri, Cornelia M van Duijn, Karen A Mather, Raquel Sánchez-Valle, Manuel Serrano-Ríos, Adelina Orellana, Lluís Tárraga, Kaj Blennow, Martijn Huisman, Ole A Andreassen, Danielle Posthuma, Jordi Clarimón, Mercè Boada, Wiesje M van der Flier, Alfredo Ramirez, Jean-Charles Lambert, Sven J van der Lee, Agustín Ruiz
Nature communications - 2023 -
Plasma Amyloid-β, Total Tau, and Neurofilament Light Chain Across the Alzheimer's Disease Clinical Spectrum: A Population-Based
Study
Yi Dong, Tingting Hou, Yuanjing Li, Rui Liu, Lin Cong, Keke Liu, Cuicui Liu, Xiaolei Han, Yifei Ren, Shi Tang, Bengt Winblad, Kaj Blennow, Yongxiang Wang, Yifeng Du, Chengxuan Qiu
JOURNAL OF ALZHEIMERS DISEASE - 2023 -
Correlation between cognitive assessment scores and circulating cerebral biomarkers in women with pre-eclampsia and
eclampsia
Emma Bokström-Rees, Henrik Zetterberg, Kaj Blennow, Roxanne Hastie, Sonja Schell, Catherine Cluver, Lina Bergman
Pregnancy Hypertension - 2023 -
14-3-3 ζ/δ-reported early synaptic injury in Alzheimer's disease is independently mediated by
sTREM2
M. S. Woo, J. Nilsson, J. Therriault, N. Rahmouni, A. Brinkmalm, Andréa Lessa Benedet, Nicholas J. Ashton, A. C. Macedo, S. Servaes, Y. T. Wang, C. Tissot, J. F. Arias, S. A. Hosseini, M. Chamoun, F. Z. Lussier, Thomas Karikari, J. Stevenson, C. Mayer, J. P. Ferrari-Souza, E. Kobayashi, G. Massarweh, M. A. Friese, T. A. Pascoal, S. Gauthier, Henrik Zetterberg, Kaj Blennow, P. Rosa-Neto
Journal of Neuroinflammation - 2023 -
Gut inflammation associated with age and Alzheimer's disease pathology: a human cohort
study
M. B. Heston, K. L. Hanslik, K. R. Zarbock, S. J. Harding, N. J. Davenport-Sis, R. L. Kerby, N. Chin, Y. Sun, A. Hoeft, Y. Deming, N. M. Vogt, T. J. Betthauser, S. C. Johnson, S. Asthana, G. Kollmorgen, I. Suridjan, N. Wild, Henrik Zetterberg, Kaj Blennow, F. E. Rey, B. B. Bendlin, T. K. Ulland
Scientific Reports - 2023 -
CSF, Blood, and MRI Biomarkers in Skogholt’s Disease - A Rare Neurodegenerative Disease in a Norwegian
Kindred
Klaus Thanke Aspli, Jan O. Aaseth, Trygve Holmøy, Kaj Blennow, Henrik Zetterberg, Bjørn Eivind Kirsebom, Tormod Fladby, Per Selnes
Brain Sciences - 2023 -
Circulating Brain Injury Biomarkers: A Novel Method for Quantification of the Impact on the Brain After Tumor
Surgery.
Isak Michaëlsson, Tobias Hallén, Louise Carstam, Mats Laesser, Isabella Björkman-Burtscher, Ann Sörbo, Kaj Blennow, Henrik Zetterberg, Asgeir Store Jakola, Thomas Skoglund
Neurosurgery - 2023 -
Elevated plasma sclerostin is associated with high brain amyloid-β load in cognitively normal older
adults
J. Yuan, S. Pedrini, R. Thota, J. Doecke, P. Chatterjee, H. R. Sohrabi, C. E. Teunissen, I. M. W. Verberk, E. Stoops, H. Vanderstichele, B. P. Meloni, C. Mitchell, S. Rainey-Smith, K. Goozee, A. C. P. Tai, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, J. J. Gao, D. L. Liu, F. Mastaglia, C. Inderjeeth, M. H. Zheng, R. N. Martins
Npj Aging - 2023 -
Robustness of CSF A beta 42/40 and A beta 42/P-tau181 measured using fully automated immunoassays to detect AD-related
outcomes
A. Leuzy, N. Mattsson-Carlgren, N. C. Cullen, E. Stomrud, S. Palmqvist, R. La Joie, L. Iaccarino, Henrik Zetterberg, G. Rabinovici, Kaj Blennow, S. Janelidze, O. Hansson
Alzheimers & Dementia - 2023 -
Ultra-high field imaging, plasma markers and autopsy data uncover a specific rostral locus coeruleus vulnerability to hyperphosphorylated
tau
M. Van Egroo, J. M. Riphagen, Nicholas J. Ashton, S. Janelidze, R. A. Sperling, K. A. Johnson, H. S. Yang, D. A. Bennett, Kaj Blennow, O. Hansson, Henrik Zetterberg, H. I. L. Jacobs
Molecular Psychiatry - 2023 -
Basal forebrain atrophy along the Alzheimer's disease continuum in adults with Down
syndrome
M. R. Aranha, M. F. Iulita, V. Montal, J. Pegueroles, A. Bejanin, L. Vaque-Alcazar, M. J. Grothe, M. Carmona-Iragui, L. Videla, B. Benejam, J. Arranz, C. Padilla, S. Valldeneu, I. Barroeta, M. Altuna, S. Fernandez, L. Ribas, N. Valle-Tamayo, D. Alcolea, S. Gonzalez-Ortiz, N. Bargallo, Henrik Zetterberg, Kaj Blennow, R. Blesa, T. Wisniewski, J. Busciglio, A. C. Cuello, A. Lleo, J. Fortea
Alzheimers & Dementia - 2023 -
Equivalence of plasma p-tau217 with cerebrospinal fluid in the diagnosis of Alzheimer's
disease
J. Therriault, S. Servaes, C. Tissot, N. Rahmouni, Nicholas J. Ashton, Andréa Lessa Benedet, Thomas Karikari, A. C. Macedo, F. Z. Lussier, J. Stevenson, Y. T. Wang, J. Fernandez-Arias, A. Stevenson, K. Q. Socualaya, A. Haeger, T. Nazneen, Aumont, Aumont,, A. Hosseini, S. Rej, P. Vitali, G. Triana-Baltzer, H. C. Kolb, J. P. Soucy, T. A. Pascoal, S. Gauthier, Henrik Zetterberg, Kaj Blennow, P. Rosa-Neto
Alzheimers & Dementia - 2023 -
Mass spectrometric simultaneous quantification of tau species in plasma shows differential associations with amyloid and tau
pathologies
Laia Montoliu-Gaya, Andréa Lessa Benedet, C. Tissot, A. Vrillon, Nicholas J. Ashton, Wagner Scheeren Brum, Juan Lantero Rodriguez, J. Stevenson, Johanna Nilsson, Mathias Sauer, N. Rahmouni, Gunnar Brinkmalm, F. Z. Lussier, T. A. Pascoal, Ingmar Skoog, Silke Kern, Henrik Zetterberg, C. Paquet, Johan Gobom, P. Rosa-Neto, Kaj Blennow
Nature Aging - 2023 -
Protein disulfide isomerases as CSF biomarkers for the neuronal response to tau
pathology
K. Wolzak, L. Vermunt, M. del Campo, M. Jorge-Oliva, A. M. van Ziel, K. W. Li, A. B. Smit, A. Chen-Ploktkin, D. J. Irwin, A. W. Lemstra, Y. Pijnenburg, W. van der Flier, Henrik Zetterberg, Johan Gobom, Kaj Blennow, P. J. Visser, C. E. Teunissen, B. M. Tijms, W. Scheper
Alzheimers & Dementia - 2023 -
Immune cell subpopulations and serum neurofilament light chain are associated with increased risk of disease worsening in multiple
sclerosis
S. Brune-Ingebretsen, E. A. Hogestol, N. K. de Rosbo, P. Berg-Hansen, C. Brunborg, Kaj Blennow, Henrik Zetterberg, F. Paul, A. Uccelli, P. Villoslada, H. F. Harbo, T. Berge
Journal of Neuroimmunology - 2023 -
Impact of asthma on the brain: evidence from diffusion MRI, CSF biomarkers and cognitive
decline
A. K. Nair, C. A. Van Hulle, B. B. Bendlin, Henrik Zetterberg, Kaj Blennow, N. Wild, G. Kollmorgen, I. Suridjan, W. W. Busse, D. C. Dean, M. A. Rosenkranz
Brain Communications - 2023 -
Plasma and cerebrospinal fluid concentrations of neurofilament light protein correlate in patients with idiopathic normal pressure
hydrocephalus
Anna Jeppsson, Åsa Sandelius, Anna Zettergren, Silke Kern, Ingmar Skoog, Kaj Blennow, Henrik Zetterberg, Carsten Wikkelsö, Per Hellström, Mats Tullberg
Fluids and Barriers of the CNS - 2023 -
Biological brain age prediction using machine learning on structural neuroimaging data: Multi-cohort validation against biomarkers of Alzheimer's disease and neurodegeneration stratified by
sex
I. Cumplido-Mayoral, M. Garcia-Prat, G. Operto, C. Falcon, M. Shekari, R. Cacciaglia, M. Mila-Aloma, L. Lorenzini, S. Ingala, A. M. Wink, H. J. Mutsaerts, C. Minguillon, K. Fauria, J. L. Molinuevo, S. Haller, G. Chetelat, A. Waldman, A. J. Schwarz, F. Barkhof, I. Suridjan, G. Kollmorgen, A. Bayfield, Henrik Zetterberg, Kaj Blennow, M. Suarez-Calvet, V. Vilaplana, J. D. Gispert
Elife - 2023 -
Differential effects of familial Alzheimer's disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic
activity
S. Schilling, Ajay Pradhan, A. Heesch, A. Helbig, Kaj Blennow, C. Koch, L. Bertgen, E. H. Koo, Gunnar Brinkmalm, Henrik Zetterberg, S. Kins, S. Eggert
Acta Neuropathologica Communications - 2023 -
Association of biological sex with clinical outcomes and biomarkers of Alzheimer's disease in adults with Down
syndrome
M. F. Iulita, A. Bejanin, E. Vilaplana, M. Carmona-Iragui, B. Benejam, L. Videla, I. Barroeta, S. Fernandez, M. Altuna, J. Pegueroles, V. Montal, S. Valldeneu, S. Gimenez, S. Gonzalez-Ortiz, S. Torres, S. E. El Bennadi, C. Padilla, M. R. Aranha, T. Estelles, I. Illan-Gala, O. Belbin, N. Valle-Tamayo, V. Camacho, E. Blessing, R. S. Osorio, S. Videla, S. Lehmann, A. J. Holland, Henrik Zetterberg, Kaj Blennow, D. Alcolea, J. Clarimon, S. H. Zaman, R. Blesa, A. Lleo, J. Fortea
Brain Communications - 2023 -
Plasma NfL is associated with the APOE epsilon 4 allele, brain imaging measurements of neurodegeneration, and lower recall memory scores in cognitively unimpaired late-middle-aged and older
adults
M. Malek-Ahmadi, Y. Su, V. Ghisays, J. Luo, V. Devadas, Y. H. Chen, W. Y. Lee, H. Protas, K. W. Chen, Henrik Zetterberg, Kaj Blennow, R. J. Caselli, E. M. Reiman
Alzheimer's Research & Therapy - 2023 -
Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma
Biomarkers
N. Mattsson-Carlgren, G. Salvado, Nicholas J. Ashton, P. Tideman, E. Stomrud, Henrik Zetterberg, R. Ossenkoppele, T. J. Betthauser, K. A. Cody, E. M. Jonaitis, R. Langhough, S. Palmqvist, Kaj Blennow, S. Janelidze, S. C. Johnson, O. Hansson
Jama Neurology - 2023 -
Brain atrophy and white matter hyperintensities are independently associated with plasma neurofilament light chain in an Asian cohort of cognitively impaired patients with concomitant cerebral small vessel
disease
J. R. Chong, S. Hilal, Nicholas J. Ashton, Thomas Karikari, A. Reilhac, H. Vrooman, Michael Schöll, Henrik Zetterberg, Kaj Blennow, C. P. Chen, M. K. P. Lai
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring - 2023 -
Plasma and cerebrospinal fluid glial fibrillary acidic protein levels in adults with Down syndrome: a longitudinal cohort
study
Laia Montoliu-Gaya, D. Alcolea, Nicholas J. Ashton, J. Pegueroles, J. Levin, B. Bosch, Juan Lantero Rodriguez, M. Carmona-Iragui, O. Wagemann, M. Balasa, Przemyslaw R. Kac, I. Barroeta, A. Llado, Wagner Scheeren Brum, L. Videla, Fernando Gonzalez-Ortiz, B. Benejam, J. J. A. Martinez, Thomas Karikari, G. Nubling, A. Bejanin, Andréa Lessa Benedet, R. Blesa, A. Lleo, Kaj Blennow, R. Sanchez-Valle, Henrik Zetterberg, J. Fortea
eBioMedicine - 2023 -
Plasma phospho-tau in Alzheimer's disease: towards diagnostic and therapeutic trial
applications
Fernando Gonzalez-Ortiz, Przemyslaw R. Kac, Wagner Scheeren Brum, Henrik Zetterberg, Kaj Blennow, Thomas Karikari
Molecular Neurodegeneration - 2023 -
Correlative Chemical Imaging and Spatial Chemometrics Delineate Alzheimer Plaque Heterogeneity at High Spatial
Resolution
Patrick M. Wehrli, J. Y. Ge, Wojciech Michno, Srinivas Koutarapu, Ambra Dreos, Durga Jha, Henrik Zetterberg, Kaj Blennow, Jörg Hanrieder
Jacs Au - 2023 -
Passive and active suicidal ideation in a population-based sample of older adults: Associations with polygenic risk scores of relevance for suicidal
behavior
Anna Zettergren, Mattias Jonson, Madeleine Mellqvist Fässberg, Jenna Najar, Therese Rydberg Sterner, Nazib Seidu, Silke Kern, Kaj Blennow, Henrik Zetterberg, Ingmar Skoog, Margda Waern
Frontiers in Psychiatry - 2023 -
Cerebrospinal fluid biomarkers of axonal and synaptic degeneration in a population-based
sample
Maya Arvidsson Rådestig, Ingmar Skoog, Tobias Skillbäck, Henrik Zetterberg, Jürgen Kern, Anna Zettergren, Ulf Andreasson, Hanna Wetterberg, Silke Kern, Kaj Blennow
Alzheimers Research & Therapy - 2023 -
Plasma neurofilament light is a predictor of neurological outcome 12 h after cardiac
arrest
H. Levin, A. Lybeck, A. Frigyesi, I. Arctaedius, B. Thorgeirsdottir, M. Annborn, M. Moseby-Knappe, N. Nielsen, T. Cronberg, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, H. Friberg, N. Mattsson-Carlgren
Critical Care - 2023 -
Prospective analysis of plasma amyloid beta and postoperative delirium in the Interventions for Postoperative Delirium: Biomarker-3
study
T. Payne, J. Taylor, C. Casey, D. Kunkel, M. Parker, Kaj Blennow, Henrik Zetterberg, R. A. Pearce, R. C. Lennertz, R. D. Sanders
British Journal of Anaesthesia - 2023 -
Transient Changes in the Plasma of Astrocytic and Neuronal Injury Biomarkers in COVID-19 Patients without Neurological
Syndromes
M. P. Lennol, Nicholas J. Ashton, O. Moreno-Perez, M. S. Garcia-Ayllon, J. M. Ramos-Rincon, M. Andres, J. M. Leon-Ramirez, V. Boix, J. Gil, Kaj Blennow, E. Merino, Henrik Zetterberg, J. Saez-Valero
International Journal of Molecular Sciences - 2023 -
High levels of kappa free light chain synthesis predict cognitive decline in relapsing-remitting multiple
sclerosis
Igal Rosenstein, Markus Axelsson, Lenka Novakova, S. Rasch, Kaj Blennow, Henrik Zetterberg, Jan Lycke
FRONTIERS IN IMMUNOLOGY - 2023 -
Cerebrospinal fluid biomarker panel of synaptic dysfunction in Alzheimer's disease and other neurodegenerative
disorders
Johanna Nilsson, K. A. Q. Cousins, Johan Gobom, E. Portelius, A. Chen-Plotkin, L. M. Shaw, M. Grossman, D. J. Irwin, J. Q. Trojanowski, Henrik Zetterberg, Kaj Blennow, Ann Brinkmalm
Alzheimers & Dementia - 2023 -
A sex-stratified analysis of neuroimmune gene expression signatures in Alzheimer's disease
brains
C. Sanfilippo, P. Castrogiovanni, M. Vinciguerra, R. Imbesi, M. Ulivieri, F. Fazio, Kaj Blennow, Henrik Zetterberg, M. Di Rosa
Geroscience - 2023 -
Identifying clinically useful biomarkers in neurodegenerative disease through a collaborative approach: the
NeuroToolKit
S. C. Johnson, M. Suarez-Calvet, I. Suridjan, C. Minguillon, J. D. Gispert, E. Jonaitis, A. Michna, M. Carboni, T. Bittner, C. Rabe, G. Kollmorgen, Henrik Zetterberg, Kaj Blennow
Alzheimers Research & Therapy - 2023 -
Whole blood transcript and protein abundance of the vascular endothelial growth factor family relate to cognitive
performance
J. B. Libby, M. Seto, O. A. Khan, D. D. Liu, V. Petyuk, N. C. Oliver, M. J. Choi, M. Whitaker, K. L. Patterson, A. B. Arul, K. A. Gifford, Kaj Blennow, Henrik Zetterberg, L. Dumitrescu, R. A. Robinson, A. L. Jefferson, T. J. Hohman
Neurobiology of Aging - 2023 -
The recency ratio assessed by story recall is associated with cerebrospinal fluid levels of neurodegeneration
biomarkers
D. Bruno, A. J. Zinkunegi, G. Kollmorgen, I. Suridjan, N. Wild, C. Carlsson, B. Bendlin, O. Okonkwo, N. Chin, B. P. Hermann, S. Asthana, Henrik Zetterberg, Kaj Blennow, R. Langhough, S. C. Johnson, K. D. Mueller
Cortex - 2023 -
Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle
loads
G. Salvado, R. Ossenkoppele, Nicholas J. Ashton, T. G. Beach, G. E. Serrano, E. M. Reiman, Henrik Zetterberg, N. Mattsson-Carlgren, S. Janelidze, Kaj Blennow, O. Hansson
Embo Molecular Medicine - 2023 -
Head-to-head comparison of plasma p-tau181, p-tau231 and glial fibrillary acidic protein in clinically unimpaired elderly with three levels of APOE4-related risk for Alzheimer's
disease
Anniina Snellman, L. L. Ekblad, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, E. Pietila, M. Koivumaki, S. Helin, M. Karrasch, Henrik Zetterberg, Kaj Blennow, J. O. Rinne
Neurobiology of Disease - 2023 -
Perioperative brain injury marker concentrations in neonatal open-heart surgery: a prospective observational
study
A. Jungner, F. Lennartsson, Isabella Björkman-Burtscher, Kaj Blennow, Henrik Zetterberg, D. Ley
Frontiers in Pediatrics - 2023 -
Matrix metalloproteinases are associated with brain atrophy in cognitively unimpaired
individuals
M. Aksnes, E. Capogna, D. Vidal-Pineiro, F. A. Chaudhry, M. Myrstad, A. V. Idland, N. B. Halaas, S. Dakhil, Kaj Blennow, Henrik Zetterberg, K. B. Walhovd, L. O. Watne, A. M. Fjell
Neurobiology of Aging - 2023 -
Plasma neurodegeneration biomarker concentrations associate with glymphatic and meningeal lymphatic measures in neurological
disorders
P. K. Eide, A. Lashkarivand, A. Pripp, L. M. Valnes, M. H. Hovd, G. Ringstad, Kaj Blennow, Henrik Zetterberg
Nature Communications - 2023 -
APOEε4 associates with microglial activation independently of Aβ plaques and tau
tangles
J. P. Ferrari-Souza, F. Z. Lussier, D. T. Leffa, J. Therriault, C. Tissot, B. Bellaver, P. C. L. Ferreira, M. Malpetti, Y. T. Wang, G. Povala, Andréa Lessa Benedet, Nicholas J. Ashton, M. Chamoun, S. Servaes, G. Bezgin, M. S. Kang, J. Stevenson, N. Rahmouni, V. Pallen, N. M. Poltronetti, J. T. O'Brlen, J. B. Rowe, A. D. Cohen, O. L. Lopez, D. L. Tudorascu, Thomas Karikari, W. E. Klunk, V. L. Villemagne, J. P. Soucy, S. Gauthier, D. O. Souza, Henrik Zetterberg, Kaj Blennow, E. R. Zimmer, P. Rosa-Neto, T. A. Pascoal
Science Advances - 2023 -
Association between Longitudinal Cerebrospinal Fluid Alzheimer's Biomarkers and the Lifestyle for Brain Health (LIBRA) Index: Findings from the European Prevention of Alzheimer's Dementia Cohort Study (EPAD
LCS)
T. S. Saunders, M. Protsiv, N. D. Jenkins, A. Solomon, Kaj Blennow, C. Ritchie, G. Muniz-Terrera
Jpad-Journal of Prevention of Alzheimers Disease - 2023 -
Glymphatic clearance estimated using diffusion tensor imaging along perivascular spaces is reduced after traumatic brain injury and correlates with plasma neurofilament light, a biomarker of injury
severity
T. Butler, L. D. Zhou, I. Ozsahin, X. H. Wang, J. Garetti, Henrik Zetterberg, Kaj Blennow, K. Jamison, M. J. de Leon, Y. Li, A. Kuceyeski, S. A. Shah
Brain Communications - 2023 -
Confounding factors of Alzheimer's disease plasma biomarkers and their impact on clinical
performance
A. P. Binette, S. Janelidze, N. Cullen, J. L. Dage, R. J. Bateman, Henrik Zetterberg, Kaj Blennow, E. Stomrud, N. Mattsson-Carlgren, O. Hansson
Alzheimers & Dementia - 2023 -
Plasma biomarker profiles in autosomal dominant Alzheimer's
disease
C. Johansson, S. Thordardottir, J. Laffita-Mesa, E. Rodriguez-Vieitez, Henrik Zetterberg, Kaj Blennow, C. Graff
Brain - 2023 -
Novel cerebrospinal fluid biomarkers correlating with shunt responsiveness in patients with idiopathic normal pressure
hydrocephalus
Sophia Weiner, A. Junkkari, M. Sauer, A. Luikku, T. Rauramaa, T. Kokkola, S. K. Herukka, Kaj Blennow, Henrik Zetterberg, V. Leinonen, Johan Gobom
Fluids and Barriers of the Cns - 2023 -
Eigenvector centrality dynamics are related to Alzheimer's disease pathological changes in non-demented
individuals
L. Lorenzini, S. Ingala, L. E. Collij, V. Wottschel, S. Haller, Kaj Blennow, G. Frisoni, G. Chetelat, P. Payoux, P. Lage-Martinez, M. Ewers, A. Waldman, J. Wardlaw, C. Ritchie, J. D. Gispert, Hjmm Mutsaerts, P. J. Visser, P. Scheltens, B. Tijms, F. Barkhof, A. M. Wink
Brain Communications - 2023 -
Preanalytical stability of plasma biomarkers for Alzheimer's disease
pathology
A. L. Sunde, I. V. Alsnes, D. Aarsland, Nicholas J. Ashton, D. A. Tovar-Rios, Giovanni de Santis, Kaj Blennow, Henrik Zetterberg, S. R. Kjosavik
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring - 2023 -
Cerebral A beta deposition precedes reduced cerebrospinal fluid and serum A beta 42/A beta 40 ratios in the App(NL-F/NL-F) knock-in mouse model of Alzheimer's
disease
E. Andersson, N. Schultz, T. Saito, T. C. Saido, Kaj Blennow, G. K. Gouras, Henrik Zetterberg, O. Hansson
Alzheimer's Research & Therapy - 2023 -
Endo-lysosomal protein concentrations in CSF from patients with frontotemporal dementia caused by CHMP2B
mutation
A. Toft, S. Sjodin, A. H. Simonsen, P. Ejlerskov, P. Roos, C. S. Musaeus, E. E. Henriksen, T. T. Nielsen, A. Brinkmalm, Kaj Blennow, Henrik Zetterberg, J. E. Nielsen
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring - 2023 -
APOE epsilon 4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired
elderly
Anniina Snellman, L. L. Ekblad, J. Tuisku, M. Koivumaki, Nicholas J. Ashton, Juan Lantero Rodriguez, Thomas Karikari, S. Helin, M. Bucci, E. Loyttyniemi, R. Parkkola, M. Karrasch, Michael Schöll, Henrik Zetterberg, Kaj Blennow, J. O. Rinne
Alzheimers Research & Therapy - 2023 -
Identification of plasma metabolites associated with modifiable risk factors and endophenotypes reflecting Alzheimer's disease
pathology
R. C. Dong, D. N. Denier-Fields, C. A. Van Hulle, G. Kollmorgen, I. Suridjan, N. Wild, Q. S. Lu, R. M. Anderson, Henrik Zetterberg, Kaj Blennow, C. M. Carlsson, S. C. Johnson, C. D. Engelman
European Journal of Epidemiology - 2023 -
Plasma neurofilament light significantly decreases following treatment in Lyme neuroborreliosis and is not associated with persistent
symptoms
H. Mens, L. Fjordside, R. Gynthersen, M. Orbaek, A. B. Andersen, Ulf Andreasson, Kaj Blennow, F. Sellebjerg, Henrik Zetterberg, A. M. Lebech
European Journal of Neurology - 2023 -
Blood-brain barrier opening of the default mode network in Alzheimer's disease with magnetic resonance-guided focused
ultrasound
Y. Meng, M. Goubran, J. S. Rabin, M. McSweeney, J. Ottoy, C. B. Pople, Y. X. Huang, A. Storace, M. Ozzoude, A. Bethune, B. Lam, W. Swardfager, C. Heyn, A. Abrahao, B. Davidson, C. Hamani, I. Aubert, Henrik Zetterberg, Nicholas J. Ashton, Thomas Karikari, Kaj Blennow, S. E. Black, K. Hynynen, N. Lipsman
Brain - 2023 -
Differential proteomic profile of lumbar and ventricular cerebrospinal
fluid
N. Rostgaard, M. H. Olsen, M. Ottenheijm, L. Drici, A. H. Simonsen, P. Plomgaard, H. Gredal, H. H. Poulsen, Henrik Zetterberg, Kaj Blennow, S. G. Hasselbalch, N. MacAulay, M. Juhler
Fluids and Barriers of the Cns - 2023 -
Functional Applications of Stable Tau Oligomers in Cell Biology and Electrophysiology
Studies
E. Hill, K. G. Moffat, M. J. Wall, Henrik Zetterberg, Kaj Blennow, Thomas Karikari
Methods in molecular biology (Clifton, N.J.) - 2023 -
A Validated Method to Prepare Stable Tau
Oligomers
E. Hill, K. G. Moffat, M. J. Wall, Henrik Zetterberg, Kaj Blennow, Thomas Karikari
Methods in molecular biology (Clifton, N.J.) - 2023 -
Plasma neurofilament light chain in memory clinic practice: Evidence from a real-life
study.
Karl Götze, Agathe Vrillon, Elodie Bouaziz-Amar, François Mouton-Liger, Jacques Hugon, Matthieu Martinet, Julien Dumurgier, Emmanuel Cognat, Henrik Zetterberg, Kaj Blennow, Claire Hourrègue, Claire Paquet, Matthieu Lilamand
Neurobiology of disease - 2023 -
Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal
dementia.
Aitana Sogorb-Esteve, Johanna Nilsson, Imogen J Swift, Carolin Heller, Martina Bocchetta, Lucy L Russell, Georgia Peakman, Rhian S Convery, John C van Swieten, Harro Seelaar, Barbara Borroni, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Rik Vandenberghe, Elizabeth Finger, Fabrizio Tagliavini, Isabel Santana, Chris R Butler, Simon Ducharme, Alexander Gerhard, Adrian Danek, Johannes Levin, Markus Otto, Sandro Sorbi, Isabelle Le Ber, Florence Pasquier, Johan Gobom, Ann Brinkmalm-Westman, Kaj Blennow, Henrik Zetterberg, Jonathan D Rohrer
Alzheimer's research & therapy - 2022 -
Astrocyte biomarker signatures of amyloid-beta and tau pathologies in Alzheimer's
disease
J. P. Ferrari-Souza, P. C. L. Ferreira, B. Bellaver, C. Tissot, Y. T. Wang, D. T. Leffa, Wagner Scheeren Brum, Andréa Lessa Benedet, Nicholas J. Ashton, M. A. De Bastiani, A. Rocha, J. Therriault, F. Z. Lussier, M. Chamoun, S. Servaes, G. Bezgin, M. S. Kang, J. Stevenson, N. Rahmouni, V. Pallen, N. M. Poltronetti, W. E. Klunk, D. L. Tudorascu, A. D. Cohen, V. L. Villemagne, S. Gauthier, Kaj Blennow, Henrik Zetterberg, D. O. Souza, Thomas Karikari, E. R. Zimmer, P. Rosa-Neto, T. A. Pascoal
Molecular Psychiatry - 2022 -
Is amyloid involved in acute neuroinflammation? A CSF analysis in
encephalitis
A. Padovani, A. Canale, L. Schiavon, S. Masciocchi, A. Imarisio, B. Risi, G. Bonzi, V. De Giuli, M. Di Luca, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, A. Pilotto
Alzheimers & Dementia - 2022 -
Central nervous system monoaminergic activity in hip osteoarthritis patients with disabling pain: associations with pain severity and central
sensitization.
Martin F Bjurström, Kaj Blennow, Henrik Zetterberg, Mikael Bodelsson, Markus Waldén, Nicholas Dietz, Sara Hall, Oskar Hansson, Michael R Irwin, Niklas Mattsson-Carlgren
Pain reports - 2022 -
Effects of age, amyloid, sex, and APOE epsilon 4 on the CSF proteome in normal
cognition
K. E. J. Wesenhagen, Johan Gobom, I. Bos, S. J. B. Vos, P. Martinez-Lage, J. Popp, M. Tsolaki, R. Vandenberghe, Y. Freund-Levi, F. Verhey, S. Lovestone, J. Streffer, V. Dobricic, L. Bertram, Kaj Blennow, M. Pikkarainen, M. Hallikainen, J. Kuusisto, M. Laakso, H. Soininen, P. Scheltens, Henrik Zetterberg, C. E. Teunissen, P. J. Visser, B. M. Tijms
Alzheimer's & Dementia - 2022 -
Plasma and CSF NfL are differentially associated with biomarker evidence of neurodegeneration in a community-based sample of
70-year-olds
Anna Dittrich, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Joel Simrén, Fiona Geiger, Anna Zettergren, S. Shams, A. Machado, E. Westman, Michael Schöll, Ingmar Skoog, Silke Kern
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring - 2022 -
Crosswalk study on blood collection-tube types for Alzheimer's disease
biomarkers
E. M. Jonaitis, Henrik Zetterberg, R. L. Koscik, T. J. Betthauser, C. A. Van Hulle, K. Hogan, L. Hegge, G. Kollmorgen, I. Suridjan, C. E. Gleason, C. D. Engelman, O. C. Okonkwo, S. Asthana, B. B. Bendlin, C. M. Carlsson, S. C. Johnson, Kaj Blennow
Alzheimer's & Dementia - 2022 -
Neurological Involvement in COVID-19 Among Non-Hospitalized Adolescents and Young
Adults
L. B. Havdal, L. L. Berven, J. Selvakumar, T. Stiansen-Sonerud, T. M. Leegaard, T. Tjade, Henrik Zetterberg, Kaj Blennow, V. B. B. Wyller
Frontiers in Neurology - 2022 -
The effect of vitamin B supplementation on neuronal injury in people living with HIV: a randomized controlled
trial
Erika Tyrberg, Lars Hagberg, Lars-Magnus Andersson, Staffan Nilsson, Aylin Yilmaz, Åsa Mellgren, Kaj Blennow, Henrik Zetterberg, Magnus Gisslén
Brain Communications - 2022 -
Postoperative delirium and changes in the blood–brain barrier, neuroinflammation, and cerebrospinal fluid lactate: a prospective cohort
study
J. Taylor, M. Parker, C. P. Casey, S. Tanabe, D. Kunkel, C. Rivera, Henrik Zetterberg, Kaj Blennow, R. A. Pearce, R. C. Lennertz, R. D. Sanders
British Journal of Anaesthesia - 2022 -
Cerebrospinal fluid neurofilament light chain differentiates primary psychiatric disorders from rapidly progressive, Alzheimer's disease and frontotemporal disorders in clinical
settings
D. Eratne, S. M. Loi, Q. X. Li, C. Stehmann, C. B. Malpas, A. Santillo, S. Janelidze, C. Cadwallader, N. Walia, B. Ney, V. Lewis, M. Senesi, C. Fowler, A. McGlade, S. Varghese, P. Ravanfar, W. Kelso, S. Farrand, M. Keem, M. Kang, A. M. Y. Goh, K. Dhiman, V. Gupta, R. Watson, N. Yassi, C. Kaylor-Hughes, R. Kanaan, P. Perucca, H. Dobson, L. Vivash, R. Ali, T. J. O'Brien, O. Hansson, Henrik Zetterberg, Kaj Blennow, M. Walterfang, C. L. Masters, S. F. Berkovic, S. Collins, D. Velakoulis, N. D. Study Grp Mi
Alzheimers & Dementia - 2022 -
Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's
disease
Nicholas J. Ashton, Andréa Lessa Benedet, Tharick A. Pascoal, Thomas Karikari, Juan Lantero Rodriguez, Wagner Scheeren Brum, S. Mathotaarachchi, J. Therriault, M. Savard, M. Chamoun, E. Stoops, C. Francois, E. Vanmechelen, S. Gauthier, E. R. Zimmer, Henrik Zetterberg, Kaj Blennow, P. Rosa-Neto
Ebiomedicine - 2022 -
Tau as a fluid biomarker of concussion and
neurodegeneration.
Iftakher Hossain, Kaj Blennow, Jussi P Posti, Henrik Zetterberg
Concussion (London, England) - 2022 -
Association of Plasma p-tau181 and p-tau231 Concentrations With Cognitive Decline in Patients With Probable Dementia With Lewy
Bodies.
Maria C Gonzalez, Nicholas J. Ashton, Bárbara Fernandes Gomes, Diego Alejandro Tovar-Rios, Frédéric Blanc, Thomas Karikari, Brit Mollenhauer, Andrea Pilotto, Afina Lemstra, Claire Paquet, Carla Abdelnour, Milica G Kramberger, Laura Bonanni, Rik Vandenberghe, Abdul Hye, Kaj Blennow, Henrik Zetterberg, Dag Aarsland
JAMA neurology - 2022 -
Cerebrospinal Fluid Sphingomyelins in Alzheimer's Disease, Neurodegeneration, and
Neuroinflammation
A. Morrow, D. J. Panyard, Y. K. Deming, E. Jonaitis, R. Dong, E. Vasiljevic, T. J. Betthauser, G. Kollmorgen, I. Suridjan, A. Bayfield, C. A. Van Hulle, Henrik Zetterberg, Kaj Blennow, C. M. Carlsson, S. Asthana, S. C. Johnson, C. D. Engelman
Journal of Alzheimers Disease - 2022 -
Screening for neurodegeneration in Langerhans cell histiocytosis with neurofilament light in
plasma
M. Sveijer, T. V. Greenwood, M. Jadersten, E. Kvedaraite, Henrik Zetterberg, Kaj Blennow, M. Lourda, D. Gavhed, J. I. Henter
British Journal of Haematology - 2022 -
Quantification of SNAP-25 with mass spectrometry and Simoa: a method comparison in Alzheimer's
disease
Johanna Nilsson, Nicholas J. Ashton, Andréa Lessa Benedet, Laia Montoliu-Gaya, Johan Gobom, T. A. Pascoal, M. Chamoun, E. Portelius, A. Jeromin, M. Mendes, Henrik Zetterberg, P. Rosa-Neto, Ann Brinkmalm, Kaj Blennow
Alzheimer's Research & Therapy - 2022 -
Neurogranin and Neurofilament Light Chain as Preclinical Biomarkers in
Scrapie
M. Betancor, S. Perez-Lazaro, A. Otero, B. Marin, I. Martin-Burriel, Kaj Blennow, J. J. Badiola, Henrik Zetterberg, R. Bolea
International Journal of Molecular Sciences - 2022 -
Association of Plasma Biomarker Levels With Their CSF Concentration and the Number and Severity of Concussions in Professional
Athletes
Pashtun Shahim, Henrik Zetterberg, Joel Simrén, Nicholas J. Ashton, G. Norato, Michael Schöll, Y. Tegner, R. Diaz-Arrastia, Kaj Blennow
Neurology - 2022 -
Optimized sample preparation and data analysis for TMT proteomic analysis of cerebrospinal fluid applied to the identification of Alzheimer's disease
biomarkers
Sophia Weiner, M. Sauer, P. J. Visser, B. M. Tijms, Egor Vorontsov, Kaj Blennow, Henrik Zetterberg, Johan Gobom
Clinical Proteomics - 2022 -
A Pragmatic, Data-Driven Method to Determine Cutoffs for CSF Biomarkers of Alzheimer Disease Based on Validation Against PET
Imaging
J. Dumurgier, S. Sabia, Henrik Zetterberg, C. E. Teunissen, B. Hanseeuw, A. Orellana, S. Schraen, A. Gabelle, M. Boada, T. Lebouvier, E. A. J. Willemse, E. Cognat, A. Ruiz, C. Hourregue, M. Lilamand, E. Bouaziz-Amar, J. L. Laplanche, S. Lehmann, F. Pasquier, P. Scheltens, Kaj Blennow, A. Singh-Manoux, C. Paquet
Neurology - 2022 -
Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total
tau.
Brandon Frank, Madeline Ally, Bailee Brekke, Henrik Zetterberg, Kaj Blennow, Michael A Sugarman, Nicholas J. Ashton, Thomas Karikari, Yorghos Tripodis, Brett Martin, Joseph N Palmisano, Eric G Steinberg, Irene Simkina, Katherine W Turk, Andrew E Budson, Maureen K O'Connor, Rhoda Au, Lee E Goldstein, Gyungah R Jun, Neil W Kowall, Thor D Stein, Ann C McKee, Ronald Killiany, Wei Qiao Qiu, Robert A Stern, Jesse Mez, Michael L Alosco
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2022 -
Association of Cerebrovascular and Alzheimer Disease Biomarkers With Cholinergic White Matter Degeneration in Cognitively Unimpaired
Individuals
N. Cedres, D. Ferreira, M. Nemy, A. Machado, J. B. Pereira, S. Shams, L. O. Wahlund, Anna Zettergren, O. Stepankova, L. Vyslouzilova, M. Eriksdotter, S. Teipel, M. J. Grothe, Kaj Blennow, Henrik Zetterberg, Michael Schöll, Silke Kern, Ingmar Skoog, E. Westman
Neurology - 2022 -
Association of APOE epsilon 4 and Plasma p-tau181 with Preclinical Alzheimer's Disease and Longitudinal Change in Hippocampus
Function
A. Salami, R. Adolfsson, M. Andersson, Kaj Blennow, A. Lundquist, A. N. Adolfsson, Michael Schöll, Henrik Zetterberg, L. Nyberg
Journal of Alzheimers Disease - 2022 -
Cardiac troponin T is elevated and increases longitudinally in ALS
patients
U. Klappe, S. Chamoun, Q. Shen, A. Finn, B. Evertsson, Henrik Zetterberg, Kaj Blennow, R. Press, K. Samuelsson, A. Manberg, F. Fang, C. Ingre
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration - 2022 -
CSF tau368/total-tau ratio reflects cognitive performance and neocortical tau better compared to p-tau181 and p-tau217 in cognitively impaired
individuals.
Joel Simrén, Wagner Scheeren Brum, Nicholas J. Ashton, Andréa Lessa Benedet, Thomas Karikari, Hlin Kvartsberg, Emma Sjons, Firoza Z Lussier, Mira Chamoun, Jenna Stevenson, Robert Hopewell, Vanessa Pallen, Keqiang Ye, Tharick A Pascoal, Henrik Zetterberg, Pedro Rosa-Neto, Kaj Blennow
Alzheimer's research & therapy - 2022 -
Differences between blood and cerebrospinal fluid glial fibrillary Acidic protein levels: The effect of sample
stability
Joel Simrén, Haley Weninger, Wagner Scheeren Brum, Shilla Khalil, Andréa Lessa Benedet, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton
Alzheimers & Dementia - 2022 -
Plasma neurofilament light chain protein is not increased in treatment-resistant schizophrenia and first-degree
relatives
D. Eratne, S. Janelidze, C. B. Malpas, S. Loi, M. Walterfane, A. Merritt, I. Diouf, Kaj Blennow, Henrik Zetterberg, B. Cilia, C. Warman, C. Bousman, I. Everall, A. Zalesky, M. Jayaram, N. Thomas, S. F. Berkovic, O. Hansson, D. Velakoulis, C. Pantelis, A. Santillo
Australian and New Zealand Journal of Psychiatry - 2022 -
Genome-Wide Association Study of Alzheimer's Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery
Dataset.
Jan Homann, Tim Osburg, Olena Ohlei, Valerija Dobricic, Laura Deecke, Isabelle Bos, Rik Vandenberghe, Silvy Gabel, Philip Scheltens, Charlotte E Teunissen, Sebastiaan Engelborghs, Giovanni Frisoni, Olivier Blin, Jill C Richardson, Regis Bordet, Alberto Lleó, Daniel Alcolea, Julius Popp, Christopher Clark, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Richard J B Dobson, Cristina Legido-Quigley, Kristel Sleegers, Christine Van Broeckhoven, Michael Wittig, Andre Franke, Christina M Lill, Kaj Blennow, Henrik Zetterberg, Simon Lovestone, Johannes Streffer, Mara Ten Kate, Stephanie J B Vos, Frederik Barkhof, Pieter Jelle Visser, Lars Bertram
Frontiers in aging neuroscience - 2022 -
Principal components from untargeted cerebrospinal fluid metabolomics associated with Alzheimer's disease
biomarkers
R. C. Dong, N. D. Denier-Fields, Q. S. Lu, I. Suridjan, G. Kollmorgen, N. Wild, T. J. Betthauser, M. C. Carlsson, S. Asthana, C. S. Johnson, Henrik Zetterberg, Kaj Blennow, C. D. Engelman
Neurobiology of Aging - 2022 -
Combined Effects of Synaptic and Axonal Integrity on Longitudinal Gray Matter Atrophy in Cognitively Unimpaired
Adults
R. Saloner, C. Fonseca, E. W. Paolillo, B. M. Asken, N. A. Djukic, S. Lee, Johanna Nilsson, Ann Brinkmalm, Kaj Blennow, Henrik Zetterberg, J. H. Kramer, K. B. Casaletto
Neurology - 2022 -
Prepandemic Alzheimer Disease Biomarkers and Anxious-Depressive Symptoms During the COVID-19 Confinement in Cognitively Unimpaired
Adults
M. Akinci, C. Pena-Gomez, G. Operto, S. Fuentes-Julian, C. Deulofeu, G. Sanchez-Benavides, M. Mila-Aloma, O. Grau-Rivera, N. Gramunt, A. Navarro, C. Minguillon, K. Fauria, I. Suridjan, G. Kollmorgen, A. Bayfield, Kaj Blennow, Henrik Zetterberg, J. L. Molinuevo, M. Suarez-Calvet, J. D. Gispert, E. M. Arenaza-Urquijo, Alfa Study Alfa Study
NEUROLOGY - 2022 -
CSF Biomarkers of Alzheimer Disease in Patients With Concomitant alpha-Synuclein
Pathology
Katheryn Alexandra Quilico Cousins, Sanaz Arezoumandan, Sanja Shellikeri, Daniel Ohm, L. M. Shaw, M. Grossman, D. Wolk, C. T. McMillan, A. Chen-Plotkin, E. Lee, J. Q. Trojanowski, Henrik Zetterberg, Kaj Blennow, D. J. Irwin
Neurology - 2022 -
Neurofilament light in plasma is a potential biomarker of central nervous system involvement in systemic lupus
erythematosus
M. B. Lauvsnes, Henrik Zetterberg, Kaj Blennow, J. T. Kvaloy, A. B. Tjensvoll, S. Maroni, M. K. Beyer, O. J. Greve, I. Kvivik, G. Alves, L. G. Goransson, E. Harboe, S. Hirohata, R. Omdal
Journal of Neurology - 2022 -
Detecting amyloid positivity in early Alzheimer's disease using combinations of plasma A beta 42/A beta 40 and
p-tau
S. Janelidze, S. Palmqvist, A. Leuzy, E. Stomrud, I. M. W. Verberk, Henrik Zetterberg, Nicholas J. Ashton, P. Pesini, L. Sarasa, J. A. Allue, C. E. Teunissen, J. L. Dage, Kaj Blennow, N. Mattsson-Carlgren, O. Hansson
Alzheimers & Dementia - 2022 -
Validation of the LUMIPULSE automated immunoassay for the measurement of core AD biomarkers in cerebrospinal
fluid.
Johan Gobom, Lucilla Parnetti, Pedro Rosa-Neto, Martin Vyhnalek, Serge Gauthier, Samuela Cataldi, Ondrej Lerch, Jan Laczo, Katerina Cechova, Marcus Clarin, Andrea I Benet, Tharick A Pascoal, Neserine Rahmouni, Manu Vandijck, Else Huyck, Nathalie Le Bastard, Jenna Stevenson, Mira Chamoun, Daniel Alcolea, Alberto Lleó, Ulf Andreasson, Marcel M Verbeek, Giovanni Bellomo, Roberta Rinaldi, Nicholas J. Ashton, Henrik Zetterberg, Katerina Sheardova, Jakub Hort, Kaj Blennow
Clinical chemistry and laboratory medicine - 2022 -
Preclinical in vivo longitudinal assessment of KG207-M as a disease-modifying Alzheimer's disease
therapeutic
M. S. Kang, M. Shin, J. Ottoy, A. A. Aliaga, S. Mathotaarachchi, K. Quispialaya, T. A. Pascoal, D. L. Collins, M. M. Chakravarty, A. Mathieu, Åsa Sandelius, Kaj Blennow, Henrik Zetterberg, G. Massarweh, J. P. Soucy, A. C. Cuello, S. Gauthier, M. Waterston, N. Yoganathan, E. Lessard, A. Haqqani, K. Rennie, D. Stanimirovic, B. Chakravarthy, P. Rosa-Neto
Journal of Cerebral Blood Flow and Metabolism - 2022
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