- Hem
- Om universitetet
- Hitta person
- Nicholas Ashton
Nicholas Ashton
Forskare
Sektionen för psykiatri och neurokemi-
Comparison of Plasma p-tau217 and [18F]FDG-PET for Identifying Alzheimer Disease in People With Early-Onset or Atypical
Dementia.
Kely Monica Quispialaya, Joseph Therriault, Antonio Aliaga, Andrea L Benedet, Nicholas J. Ashton, Thomas Karikari, Arthur Cassa Macedo, Nesrine Rahmouni, Cécile Tissot, Jaime Fernandez Arias, Yi-Ting Tina Wang, Lydia Trudel, Seyyed Ali Hosseini, Takashi Matsudaira, Tevy Chan, Tharick Pascoal, Brian Gilfix, Paolo Vitali, Eduardo R Zimmer, Karine Provost, Jean-Paul Soucy, Serge Gauthier, Henrik Zetterberg, Bertrand J Jean-Claude, Kaj Blennow, Pedro Rosa-Neto
Neurology - 2025 -
Anthocyanin supplementation in adults at risk for dementia: a randomized controlled trial on its cardiometabolic and anti-inflammatory biomarker
effects
Miguel German Borda, Robinson Ramirez-Velez, Felipe Botero-Rodriguez, Jonathan Patricio-Baldera, Chiara de Lucia, Ilaria Pola, George E. Barreto, Khadija Khalifa, Anne Katrine Bergland, Miia Kivipelto, Tommy Cederholm, Henrik Zetterberg, Nicholas J. Ashton, Clive Ballard, Richard Siow, Dag Aarsland, Jenni NJ FINGER
GEROSCIENCE - 2025 -
Tau profiling across Alzheimer's disease staging reveals vulnerability to disease
pathophysiology
Gleb Bezgin, Tharick A. Pascoal, Joseph Therriault, Firoza Z. Lussier, Stijn Servaes, Min Su Kang, Melissa Savard, Cecile Tissot, Jenna Stevenson, Yi-Ting Wang, Julie Ottoy, Nesrine Rahmouni, Jaime Fernandez-Arias, Seyyed Ali Hosseini, Etienne Aumont, Brandon Hall, Nina Margherita Poltronetti, Vanessa Pallen, Andréa Lessa Benedet, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Thomas Karikari, Tatsuhiro Terada, Mira Chamoun, Sulantha Mathotaarachchi, Arthur Cassa Macedo, Alyssa Stevenson, Peter Kunach, Gassan Massarweh, Paolo Vitali, Jean-Paul Soucy, Yasser Iturria-Medina, Serge Gauthier, Pedro Rosa-Neto
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING - 2025 -
Dissection of blood-brain barrier dysfunction through CSF PDGFRβ and amyloid, tau, neuroinflammation, and synaptic CSF biomarkers in neurodegenerative
disorders
Agathe Vrillon, Nicholas J. Ashton, Elodie Bouaziz-Amar, Francois Mouton-Liger, Emmanuel Cognat, Julien Dumurgier, Matthieu Lilamand, Thomas K. Karikari, Vincent Prevot, Henrik Zetterberg, Kaj Blennow, Claire Paquet
EBIOMEDICINE - 2025 -
Plasma p-tau217 in Alzheimer's disease: Lumipulse and ALZpath SIMOA head-to-head
comparison.
Andrea Pilotto, Virginia Quaresima, Chiara Trasciatti, Chiara Tolassi, Diego Bertoli, Cristina Mordenti, Alice Galli, Andrea Rizzardi, Salvatore Caratozzolo, Andrea Zancanaro, José Contador, Oskar Hansson, Sebastian Palmqvist, Giovanni de Santis, Henrik Zetterberg, Kaj Blennow, Duilio Brugnoni, Marc Suárez-Calvet, Nicholas J. Ashton, Alessandro Padovani
Brain : a journal of neurology - 2025 -
Plasma phosphorylated tau (p-tau231) and total tau (t-tau) as prognostic markers of neurological outcome after cardiac arrest - a multicentre
study.
Bergþóra Þorgeirsdóttir, Theodor Sievert, Anna Lybeck, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Hans Friberg, Attila Frigyesi
Resuscitation - 2025 -
Plasma Alzheimer's disease biomarker variability: Amyloid-independent and amyloid-dependent
factors.
Eun Hye Lee, Sung Hoon Kang, Daeun Shin, Young Ju Kim, Henrik Zetterberg, Kaj Blennow, Fernándo González-Ortiz, Nicholas J. Ashton, Bo Kyoung Cheon, Heejin Yoo, Hongki Ham, Jihwan Yun, Jun Pyo Kim, Hee Jin Kim, Duk L Na, Hyemin Jang, Sang Won Seo
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2025 -
Disentangling relationships between Alzheimer's disease plasma biomarkers and established biomarkers in patients of tertiary memory
clinics.
Marina Bluma, Konstantinos Chiotis, Marco Bucci, Irina Savitcheva, Anna Matton, Miia Kivipelto, Andreas Jeromin, Giovanni de Santis, Guglielmo Di Molfetta, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Agneta Nordberg
EBioMedicine - 2025 -
Sex differences in the trajectories of plasma biomarkers, brain atrophy, and cognitive decline relative to amyloid
onset
Cassandra M. Joynes, Murat Bilgel, Yang An, Abhay R. Moghekar, Nicholas J. Ashton, Przemyslaw R. Kac, Thomas Karikari, Kaj Blennow, Henrik Zetterberg, Madhav Thambisetty, Luigi Ferrucci, Susan M. Resnick, Keenan A. Walker
ALZHEIMERS & DEMENTIA - 2025 -
Peripheral innate immunophenotype in neurodegenerative disease: blood-based profiles and links to
survival
Alexandra Strauss, Peter Swann, Stacey L. Kigar, Rafailia Christou, Natalia Savinykh Yarkoni, Lorinda Turner, Alexander G. Murley, Leonidas Chouliaras, Noah Shapiro, Nicholas J. Ashton, George Savulich, W. Richard Bevan-Jones, Ajenthan Surendranthan, Kaj Blennow, Henrik Zetterberg, John T. O'Brien, James B. Rowe, Maura Malpetti
MOLECULAR PSYCHIATRY - 2025 -
The detection of GRN mutation carriers by progranulin blood protein levels from finger-stick
collection
Hanna Huber, Valentina Cantoni, Daniele Altomare, Lana Grötschel, Laia Montoliu-Gaya, Francisco J Meda, Hlin Kvartsberg, Ilenia Libri, Maria Sofia Cotelli, Henrik Zetterberg, Kaj Blennow, Barbara Borroni, Nicholas J. Ashton
ALZHEIMERS & DEMENTIA - 2025 -
Plasma phosphorylated tau and neuropsychiatric symptoms in dementia with Lewy
bodies
Lucy L. Gibson, Maria C. Gonzalez, Nicholas J. Ashton, Diego Tovar-Rios, Frédéric Blanc, Andrea Pilotto, Afina Lemstra, Claire Paquet, Clive Ballard, Henrik Zetterberg, Dag Aarsland
Alzheimer's and Dementia - 2025 -
Associations between the logical memory test story recall metrics and plasma biomarkers for Alzheimer's disease in individuals free of
dementia
Ainara Jauregi-Zinkunegi, Rachael E. Wilson, Rebecca E. Langhough, Nicholas J. Ashton, Kaj Blennow, Sterling C. Johnson, Henrik Zetterberg, Davide Bruno, Kimberly D. Mueller
CLINICAL NEUROPSYCHOLOGIST - 2025 -
Plasma phospho-tau217 for Alzheimer's disease diagnosis in primary and secondary care using a fully automated
platform
Sebastian Palmqvist, Noelle Warmenhoven, Federica Anastasi, Andrea Pilotto, Shorena Janelidze, Pontus Tideman, Erik Stomrud, Niklas Mattsson-Carlgren, Ruben Smith, Rik Ossenkoppele, Kübra Tan, Anna Dittrich, Ingmar Skoog, Henrik Zetterberg, Virginia Quaresima, Chiara Tolassi, Kina Hoglund, Duilio Brugnoni, Albert Puig-Pijoan, Aida Fernandez-Lebrero, Jose Contador, Alessandro Padovani, Mark Monane, Philip B. Verghese, Joel B. Braunstein, Silke Kern, Kaj Blennow, Nicholas J. Ashton, Marc Suarez-Calvet, Oskar Hansson
NATURE MEDICINE - 2025 -
Sex differences on tau, astrocytic, and neurodegenerative plasma
biomarkers
Jacob Labonte, Michael A. Sugarman, Erika Pettway, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Thomas Karikari, Hugo J. Aparicio, Brandon Frank, Yorghos Tripodis, Brett Martin, Joseph N. Palmisano, Eric G. Steinberg, Irene Simkin, Lindsay A. Farrer, Gyungah R. Jun, Katherine W. Turk, Andrew E. Budson, Maureen K. O'Connor, Rhoda Au, Lee E. Goldstein, Robert A. Stern, Thor D. Stein, Ann C. Mckee, Wei Qiao Qiu, Jesse Mez, Sarah J. Banks, Michael L. Alosco
JOURNAL OF ALZHEIMERS DISEASE - 2025 -
Increased Cerebrospinal Fluid Angiotensin-Converting Enzyme 2 Fragments as a Read-Out of Brain Infection in Patients With COVID-19
Encephalopathy
Matthew P. Lennol, Maria-Salud Garcia-Ayllon, Carlos Aviles-Granados, Chiara Trasciatti, Chiara Tolassi, Virginia Quaresima, Davide Arici, Viviana Cristillo, Irene Volonghi, Francesca Caprioli, Valeria De Giuli, Sara Mariotto, Sergio Ferrari, Gianluigi Zanusso, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Alessandro Padovani, Andrea Pilotto, Javier Saez-Valero
JOURNAL OF INFECTIOUS DISEASES - 2025 -
Biofluid-based staging of Alzheimer's
disease
Juan Lantero Rodriguez, Laia Montoliu-Gaya, Nicholas J. Ashton, Ilaria Pola, Joseph Therriault, Nesrine Rahmouni, Wagner Scheeren Brum, Stijn Servaes, Jenna Stevenson, Guglielmo Di Molfetta, Burak Arslan, Jesse Klostranec, Paolo Vitali, Maxime Montembeault, Serge Gauthier, Cecile Tissot, Arthur C. Macedo, Tharick A. Pascoal, Andreas Jeromin, Johan Gobom, Kaj Blennow, Henrik Zetterberg, Pedro Rosa-Neto, Andrea L Benedet
ACTA NEUROPATHOLOGICA - 2025 -
Loneliness and Biomarkers of Alzheimer's Disease, Axonal Damage, and Astrogliosis: A Coordinated Analysis of Two Longitudinal
Cohorts
Antonio Terracciano, Keenan A. Walker, Yang An, Murat Bilgel, Angelina R. Sutin, Martina Luchetti, Selin Karakose, Yannick Stephan, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Thomas Karikari, Przemyslaw R. Kac, Abhay R. Moghekar, Madhav Thambisetty, Luigi Ferrucci, Susan M. Resnick
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES - 2025 -
Association of Plasma Biomarkers With Longitudinal Atrophy and Microvascular Burden on MRI Across Neurodegenerative and Cerebrovascular
Diseases
Erlan Sanchez, Gillian T. Coughlan, Tim Wilkinson, Joel Ramirez, Saira Saeed Mirza, Andree-Ann Baril, Allison A. Dilliott, Andrew Frank, Anthony E. Lang, Ayman Hassan, Bruce G. Pollock, Christopher J. M. Scott, Connie Marras, Corinne E. Fischer, Dallas Seitz, Daniela Andriuta, Dar Dowlatshahi, David A. Grimes, David F. Tang-Wai, Demetrios J. Sahlas, Ekaterina A. Rogaeva, Elizabeth Finger, John F. Robinson, Kubra Tan, Malcolm A. Binns, Maria Carmela Tartaglia, Michael J. Borrie, Michael J. Strong, Miracle Ozzoude, Nuwan D. Nanayakkara, Rafaella A. Goncalves, Robert Bartha, Robert A. Hegele, Sali M. K. Farhan, Sandra E. Black, Sanjeev Kumar, Sean P. Symons, Seyyed M. H. Haddad, Stephen H. Pasternak, Stephen R. Arnott, Tarek K. Rajji, Thomas Steeves, Walter Swardfager, Nicholas J. Ashton, Hlin Kvartsberg, Henrik Zetterberg, Douglas P. Munoz, Mario Masellis
NEUROLOGY - 2025 -
A head-to-head comparison of plasma biomarkers to detect Alzheimer's disease in a memory
clinic
Federica Anastasi, Aida Fernandez-Lebrero, Nicholas J. Ashton, Paula Ortiz-Romero, Javier Torres-Torronteras, Armand Gonzalez-Escalante, Marta Mila-Aloma, Jose Contador, Greta Garcia-Escobar, Rosa Maria Manero-Borras, Irene Navalpotro-Gomez, Esther Jimenez-Moyano, Aparna Sahajan, Qinyu Hao, Bingqing Zhang, Andreas Jeromin, Nathalie Le Bastard, Alicia Nadal, Tahmine Mousavi, Gwendlyn Kollmorgen, Margherita Carboni, Oriol Grau-Rivera, Henrik Zetterberg, Marta del Campo, Kaj Blennow, Albert Puig-Pijoan, Marc Suarez-Calvet
ALZHEIMERS & DEMENTIA - 2025 -
Evaluation of two plasma-based proteotyping assays against <i>APOE</i> ε4 genotyping in a memory clinic setting: The Gothenburg H70 Clinical
Studies
Anna Dittrich, Kaj Blennow, Kübra Tan, Andrea L Benedet, Ingmar Skoog, Kina Hoglund, Nicholas J. Ashton, Henrik Zetterberg, Silke Kern
ALZHEIMERS & DEMENTIA - 2025 -
Plasma p-tau217 identifies cognitively normal older adults who will develop cognitive impairment in a 10-year
window
Yara Yakoub, Fernando Gonzalez-Ortiz, Nicholas J. Ashton, Christine Dery, Cherie Strikwerda-Brown, Frederic St-Onge, Valentin Ourry, Michael Schöll, Maiya R. Geddes, Simon Ducharme, Maxime Montembeault, Pedro Rosa-Neto, Jean-Paul Soucy, John C. S. Breitner, Henrik Zetterberg, Kaj Blennow, Judes Poirier, Sylvia Villeneuve
ALZHEIMERS & DEMENTIA - 2025 -
The impact of kidney function on Alzheimer's disease blood biomarkers: implications for predicting amyloid-β
positivity.
Burak Arslan, Wagner Scheeren Brum, Ilaria Pola, Joseph Therriault, Nesrine Rahmouni, Jenna Stevenson, Stijn Servaes, Kübra Tan, Paolo Vitali, Maxime Montembeault, Jesse Klostranec, Arthur C Macedo, Cecile Tissot, Serge Gauthier, Juan Lantero Rodriguez, Eduardo R Zimmer, Kaj Blennow, Henrik Zetterberg, Pedro Rosa-Neto, Andrea L Benedet, Nicholas J. Ashton
Alzheimer's Research & Therapy - 2025 -
Machine learning prediction of tau-PET in Alzheimer's disease using plasma, MRI, and clinical
data
Linda Karlsson, Jacob Vogel, Ida Arvidsson, Kalle Astrom, Olof Strandberg, Jakob Seidlitz, Richard A. I. Bethlehem, Erik Stomrud, Rik Ossenkoppele, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Sebastian Palmqvist, Ruben Smith, Shorena Janelidze, Renaud La Joie, Gil D. Rabinovici, Alexa Pichet Binette, Niklas Mattsson-Carlgren, Oskar Hansson
ALZHEIMERS & DEMENTIA - 2025 -
Predicting survival rate by plasma biomarkers and clinical variables in syndromes associated with frontotemporal lobar
degeneration.
Maria Sofia Cotelli, Barbara Tarantino, Kübra Tan, Hanna Huber, Valentina Cantoni, Valeria Bracca, Roberto Gasparotti, Enrico Premi, Giancarlo Logroscino, Andrea L Benedet, Kaj Blennow, Henrik Zetterberg, Mario Grassi, Nicholas J. Ashton, Barbara Borroni
Alzheimer's & Dementia - 2025 -
Synaptosomal-Associated Protein 25 kDA (SNAP-25) Levels in Cerebrospinal Fluid: Implications for Alzheimer's Disease Diagnosis and
Monitoring
Sofia Hjorth Wolner, Helena Sophia Gleerup, Christian Sandoe Musaeus, Peter Hogh, Nicholas J. Ashton, Ann Brinkmalm, Johanna Nilsson, Lana Grötschel, Henrik Zetterberg, Kaj Blennow, Steen Gregers Hasselbalch, Anne Byriel Walls, Anja Hviid Simonsen
SYNAPSE - 2025 -
Differential roles of Alzheimer's disease plasma biomarkers in stepwise biomarker-guided
diagnostics
Hyemin Jang, Daeun Shin, Heejin Yoo, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J. Ashton, Theresa A. Day, Eun Hye Lee, Jihwan Yun, Duk L. Na, Hee Jin Kim, Sung Hoon Kang, Ko Woon Kim, Si Eun Kim, Yeo Jin Kim, Yeshin Kim, Jaeho Kim, Chi-Hun Kim, Min Young Chun, Na Yeon Jung, Soo Hyun Cho, Jun Pyo Kim, Sang Won Seo
ALZHEIMERS & DEMENTIA - 2025 -
Identify biological Alzheimer's disease using a novel nucleic acid-linked protein
immunoassay
Yi-Ting Wang, Nicholas J. Ashton, Joseph Therriault, Andrea L Benedet, Arthur C. Macedo, Ilaria Pola, Etienne Aumont, Guglielmo Di Molfetta, Jaime Fernandez-Arias, Kübra Tan, Nesrine Rahmouni, Stijn Johannes G. Servaes, Richard Isaacson, Tevy Chan, Seyyed Ali Hosseini, Cecile Tissot, Sulantha Mathotaarachchi, Jenna Stevenson, Firoza Z. Lussier, Tharick A. Pascoal, Serge Gauthier, Kaj Blennow, Henrik Zetterberg, Pedro Rosa-Neto
Brain Communications - 2025 -
Inflammation biomarkers and Alzheimer's disease: A pilot study using
NULISAseq
Guglielmo Di Molfetta, Ilaria Pola, Kübra Tan, Richard Isaacson, Kaj Blennow, Nicholas J. Ashton, Andrea L Benedet, Henrik Zetterberg
Alzheimer's & Dementia - 2025 -
Association between herpes simplex virus infection and Alzheimer's disease biomarkers: analysis within the MAPT
trial
Morgane Linard, Isabelle Garrigue, Bruno Vellas, Nicola Coley, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Pierre Payoux, Anne-Sophie Salabert, Jean-Francois Dartigues, Joachim Mazere, Sandrine Andrieu, Catherine Helmer
SCIENTIFIC REPORTS - 2025 -
Clinical utility of plasma p-tau217 in identifying abnormal brain amyloid burden in an Asian cohort with high prevalence of concomitant cerebrovascular
disease
Joyce R. Chong, Saima Hilal, Boon Yeow Tan, Narayanaswamy Venketasubramanian, Michael Schöll, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Christopher P. Chen, Mitchell K. P. Lai
ALZHEIMERS & DEMENTIA - 2025 -
Short-term variability of Alzheimer's disease plasma biomarkers in a mixed memory clinic
cohort
Frederikke Kragh Clemmensen, Mathias Holsey Gramkow, Anja Hviid Simonsen, Nicholas J. Ashton, Hanna Huber, Kaj Blennow, Henrik Zetterberg, Gunhild Waldemar, Steen Gregers Hasselbalch, Kristian Steen Frederiksen
ALZHEIMERS RESEARCH & THERAPY - 2025 -
Plasma biomarkers of amyloid, tau, astrogliosis, and axonal injury in a mixed memory clinic
cohort
Helena Sophia Gleerup, Anja Hviid Simonsen, Lana Grötschel, Mathias Holsey Gramkow, Peter Hogh, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Steen Gregers Hasselbalch
ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING - 2025 -
Plasma p-tau and neurofilament/p-tau ratio in differentiating Alzheimer's disease from syndromes associated with frontotemporal lobar
degeneration
Alberto Benussi, Hanna Huber, Kübra Tan, Valentina Cantoni, Jasmine Rivolta, Maria Sofia Cotelli, Andrea L Benedet, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Barbara Borroni
ALZHEIMERS & DEMENTIA - 2025 -
A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker
tests.
Noëlle Warmenhoven, Gemma Salvadó, Shorena Janelidze, Niklas Mattsson-Carlgren, Divya Bali, Anna Orduña Dolado, Hartmuth Kolb, Gallen Triana-Baltzer, Nicolas R Barthélemy, Suzanne E Schindler, Andrew J Aschenbrenner, Cyrus A Raji, Tammie L S Benzinger, John C Morris, Laura Ibanez, Jigyasha Timsina, Carlos Cruchaga, Randall J Bateman, Nicholas J. Ashton, Burak Arslan, Henrik Zetterberg, Kaj Blennow, Alexa Pichet Binette, Oskar Hansson
Brain : a journal of neurology - 2024 -
Blood inflammation relates to neuroinflammation and survival in frontotemporal lobar
degeneration
Maura Malpetti, Peter Swann, Kamen A. Tsvetanov, Leonidas Chouliaras, Alexandra Strauss, Tanatswa Chikaura, Alexander G. Murley, Nicholas J. Ashton, Peter Barker, Peter Simon Jones, Tim D. Fryer, Young T. Hong, Thomas E. Cope, George Savulich, Duncan Street, William Richard Bevan-Jones, Timothy Rittman, Kaj Blennow, Henrik Zetterberg, Franklin Aigbirhio, John T. O'Brien, James B. Rowe
BRAIN - 2024 -
The Alzheimer's Association Global Biomarker Standardization Consortium (GBSC) plasma phospho-tau Round Robin
study.
Nicholas J. Ashton, Ashvini Keshavan, Wagner Scheeren Brum, Ulf Andreasson, Burak Arslan, Mathias Droescher, Stefan Barghorn, Jeroen Vanbrabant, Charlotte Lambrechts, Maxime Van Loo, Erik Stoops, Shweta Iyengar, HaYeun Ji, Xiaomei Xu, Alex Forrest-Hay, Bingqing Zhang, Yuling Luo, Andreas Jeromin, Manu Vandijck, Nathalie Le Bastard, Hartmuth Kolb, Gallen Triana-Baltzer, Divya Bali, Shorena Janelidze, Shieh-Yueh Yang, Catherine Demos, Daniel Romero, George Sigal, Jacob Wohlstadter, Kishore Malyavantham, Meenakshi Khare, Alexander Jethwa, Laura Stoeckl, Johan Gobom, Przemysław R Kac, Fernando Gonzalez-Ortiz, Laia Montoliu-Gaya, Oskar Hansson, Robert A Rissman, Maria C Carillo, Leslie M Shaw, Kaj Blennow, Jonathan M Schott, Henrik Zetterberg
medRxiv : the preprint server for health sciences - 2024 -
Cerebrospinal fluid biomarker panel for synaptic dysfunction in a broad spectrum of neurodegenerative
diseases.
Johanna Nilsson, Alexa Pichet Binette, Sebastian Palmqvist, Wagner Scheeren Brum, Shorena Janelidze, Nicholas J. Ashton, Nicola Spotorno, Erik Stomrud, Johan Gobom, Henrik Zetterberg, Ann Brinkmalm, Kaj Blennow, Oskar Hansson
Brain - 2024 -
Robust Symptomatic Subtypes of Typical Alzheimer’s Disease Characterized by Differential Neuropathological Patterns and Functional
Decline
Hussein Zalzale, Pamela C.L. Ferreira, Peter Lemaire, Marina Scop Madeiros, Carolina Soares, Bruna Bellaver, Guilherme Bauer-Negrini, Firoza Z. Lussier, Guilherme Povala, João Pedro Ferrari-Souza, Sarah Abbas, Cristiano Schaffer Aguzzoli, Matheus Scarpatto Rodrigues, Francieli Rohden, Livia Amaral, Douglas Teixeira Leffa, Markley Oliveira, Dana Tudorascu, Cécile Tissot, Nesrine Rahmouni, Nicholas J. Ashton, Kaj Blennow, Chang Hyung Hong, Sang Joon Son, Pedro Rosa-Neto, Ann D. Cohen, Oscar L. Lopez, Victor L. Villemagne, Tharick A. Pascoal
Alzheimer's & Dementia - 2024 -
Hippocampal degeneration is associated with GFAP levels in individuals with vascular dementia independently of
amyloidosis
Markley Oliveira, Bruna Bellaver, Firoza Z. Lussier, Pamela C.L. Ferreira, Guilherme Povala, Douglas Teixeira Leffa, Guilherme Bauer-Negrini, Matheus Scarpatto Rodrigues, Sarah Abbas, Hussein Zalzale, Francieli Rohden, Cynthia Felix, Carolina Soares, Pampa Saha, Emma Patrice Ruppert, Vitor Hugo Machado, Andreia Silva da Rocha, Dana Tudorascu, Andrea L Benedet, Nicholas J. Ashton, Cécile Tissot, Joseph Therriault, Stijn Servaes, Jenna Stevenson, Nesrine Rahmouni, Chang Hyung Hong, Hyun Woong Roh, Eduardo R. Zimmer, Kaj Blennow, Henrik Zetterberg, Thomas Karikari, Pedro Rosa-Neto, Sang Joon Son, Tharick A. Pascoal
Alzheimer's & Dementia - 2024 -
Proteome-wide analyses identifies plasma immune regulators of amyloid-beta
progression
Michael R. Duggan, Gabriela T. Gomez, Murat Bilgel, Jingsha Chen, Nicola Fattorelli, Timothy J. Hohman, Renzo Mancuso, Jenifer Cordon, Tonnar Castellano, Mary Ellen I. Koran, Julián Candia, Alexandria Lewis, Abhay Moghekar, Nicholas J. Ashton, Przemysław R Kac, Thomas Karikari, Kaj Blennow, Henrik Zetterberg, Anna Martinez-Muriana, Bart De Strooper, Madhav Thambisetty, Luigi Ferrucci, Rebecca F. Gottesman, Josef Coresh, Susan M. Resnick, Keenan A. Walker
Alzheimer's & Dementia - 2024 -
Evaluating Congruence Between Clinical and Biological Staging Across The Alzheimer’s Disease
Spectrum
Hussein Zalzale, Marina Scop Madeiros, Carolina Soares, Guilherme Bauer-Negrini, Guilherme Povala, Pamela C.L. Ferreira, Livia Amaral, Firoza Z. Lussier, Bruna Bellaver, Sarah Abbas, Matheus Scarpatto Rodrigues, Dana Tudorascu, Markley Oliveira, Cynthia Felix, Douglas Teixeira Leffa, Cécile Tissot, Cristiano Schaffer Aguzzoli, Emma Patrice Ruppert, Pampa Saha, Nesrine Rahmouni, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Belen Pascual, Brian A. Gordon, William J. Jagust, Val J. Lowe, Thomas Karikari, Hwamee Oh, William E. Klunk, David N. Soleimani-Meigooni, Pedro Rosa-Neto, Suzanne L. Baker, Tharick A. Pascoal
Alzheimer's & Dementia - 2024 -
Alzheimer's disease-Biomarkers, clinical evaluation or
both?
Joel Simrén, Nicholas J. Ashton, Marc Suárez-Calvet, Henrik Zetterberg
Journal of neuropsychology - 2024 -
Diagnosis of Alzheimer's disease using plasma biomarkers adjusted to clinical
probability.
Joseph Therriault, Shorena Janelidze, Andréa Lessa Benedet, Nicholas J. Ashton, Javier Arranz Martínez, Armand Gonzalez-Escalante, Bruna Bellaver, Daniel Alcolea, Agathe Vrillon, Helmet Karim, Michelle M Mielke, Chang Hyung Hong, Hyun Woong Roh, José Contador, Albert Puig Pijoan, Alicia Algeciras-Schimnich, Prashanthi Vemuri, Jonathan Graff-Radford, Val J Lowe, Thomas Karikari, Erin Jonaitis, Wagner Scheeren Brum, Cécile Tissot, Stijn Servaes, Nesrine Rahmouni, Arthur C Macedo, Jenna Stevenson, Jaime Fernandez-Arias, Yi-Ting Wang, Marcel S Woo, Manuel A Friese, Wan Lu Jia, Julien Dumurgier, Claire Hourregue, Emmanuel Cognat, Pamela Lukasewicz Ferreira, Paolo Vitali, Sterling Johnson, Tharick A Pascoal, Serge Gauthier, Alberto Lleó, Claire Paquet, Ronald C Petersen, David Salmon, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Erik Stomrud, Douglas Galasko, Sang Joon Son, Henrik Zetterberg, Juan Fortea, Marc Suárez-Calvet, Clifford R Jack, Kaj Blennow, Oskar Hansson, Pedro Rosa-Neto
Nature aging - 2024 -
Sex differences in the relationships between 24-h rest-activity patterns and plasma markers of Alzheimer’s disease
pathology
Maxime Van Egroo, Elise Beckers, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Heidi I.L. Jacobs
Alzheimer's Research and Therapy - 2024 -
Vascular risk burden is a key player in the early progression of Alzheimer's
disease
Joao Pedro Ferrari-Souza, Wagner Scheeren Brum, Lucas A. Hauschild, Lucas U. Da Ros, Pamela C. L. Ferreira, Bruna Bellaver, Douglas T. Leffa, Andrei Bieger, Cecile Tissot, Firoza Z. Lussier, Marco Antonio De Bastiani, Guilherme Povala, Andréa Lessa Benedet, Joseph Therriault, Yi-Ting Wang, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Sheila O. Martins, Diogo O. Souza, Pedro Rosa-Neto, Thomas Karikari, Tharick A. Pascoal, Eduardo R. Zimmer
NEUROBIOLOGY OF AGING - 2024 -
Plasma concentrations of glial fibrillary acidic protein, neurofilament light, and tau in Alexander
disease
Nicholas J. Ashton, Guglielmo Di Molfetta, Kübra Tan, Kaj Blennow, Henrik Zetterberg, Albee Messing
Neurological Sciences - 2024 -
Plasma phosphorylated tau181 outperforms [18F] fluorodeoxyglucose positron emission tomography in the identification of early Alzheimer
disease
Kely Monica Quispialaya, Joseph Therriault, Antonio Aliaga, Cecile Tissot, Stijn Servaes, Nesrine Rahmouni, Thomas Karikari, Andréa Lessa Benedet, Nicholas J. Ashton, Arthur C. Macedo, Firoza Z. Lussier, Jenna Stevenson, Yi-Ting Wang, Jaime Fernandez Arias, Ali Hosseini, Takashi Matsudaira, Bertrand Jean-Claude, Brian M. Gilfix, Eduardo R. Zimmer, Jean-Paul Soucy, Tharick A. Pascoal, Serge Gauthier, Henrik Zetterberg, Kaj Blennow, Pedro Rosa-Neto
EUROPEAN JOURNAL OF NEUROLOGY - 2024 -
Association of glial fibrillary acid protein, Alzheimer's disease pathology and cognitive
decline
Debora E. Peretti, Cecilia Boccalini, Federica Ribaldi, Max Scheffler, Moira Marizzoni, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Giovanni B. Frisoni, Valentina Garibotto
BRAIN - 2024 -
Cerebrospinal fluid p-tau181, 217, and 231 in definite Creutzfeldt-Jakob disease with and without concomitant
pathologies
Andreja Emersic, Nicholas J. Ashton, Agathe Vrillon, Juan Lantero Rodriguez, Jernej Mlakar, Milica Gregoric Kramberger, Fernando Gonzalez-Ortiz, Przemyslaw R. Kac, Maciej Dulewicz, Jörg Hanrieder, Eugeen Vanmechelen, Uros Rot, Henrik Zetterberg, Thomas Karikari, Sasa Cucnik, Kaj Blennow
ALZHEIMERS & DEMENTIA - 2024 -
Tau protein profiling in tauopathies: a human brain
study
Juan Lantero Rodriguez, Elena Camporesi, Laia Montoliu-Gaya, Johan Gobom, Diana Piotrowska, Maria Olsson, Irena Matečko-Burmann, Bruno Becker, Ann Brinkmalm, Björn Marcus Burmann, Michael Perkinton, Nicholas J. Ashton, Nick C. Fox, Tammaryn Lashley, Henrik Zetterberg, Kaj Blennow, Gunnar Brinkmalm
MOLECULAR NEURODEGENERATION - 2024 -
Data-driven CSF biomarker profiling: imaging and clinical outcomes in a cohort at risk of Alzheimer's
disease.
Georgette Argiris, Muge Akinci, Cleofé Peña-Gómez, Eleni Palpatzis, Marina Garcia-Prat, Mahnaz Shekari, Kaj Blennow, Henrik Zetterberg, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Nicholas J. Ashton, Thomas Karikari, Ann Brinkmalm-Westman, Juan Lantero Rodriguez, Karine Fauria, Gonzalo Sánchez-Benavides, Oriol Grau-Rivera, Marc Suárez-Calvet, Eider M Arenaza-Urquijo, For The Alfa Study
Alzheimer's research & therapy - 2024 -
Hormone therapy is associated with lower Alzheimer's disease tau biomarkers in post-menopausal females -evidence from two independent
cohorts.
Yi-Ting Wang, Joseph Therriault, Cécile Tissot, Stijn Servaes, Nesrine Rahmouni, Arthur Cassa Macedo, Jaime Fernandez-Arias, Sulantha S Mathotaarachchi, Jenna Stevenson, Firoza Z Lussier, Andréa Lessa Benedet, Tharick A Pascoal, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Serge Gauthier, Pedro Rosa-Neto
Alzheimer's research & therapy - 2024 -
Nested case control study of prevalence and aetiology of dementia in a rural Ugandan population, and a situational analysis of services available for affected families: a protocol. Part of the DEPEND Uganda study (Dementia EPidemiology, unmet Need and co-Developing
Solutions)
Josephine Prynn, Racheal Alinaitwe, Beatrice Kimono, Tunde Peto, Nicholas J. Ashton, Claire J. Steves, Joseph Mugisha, Martin Prince
Wellcome Open Research - 2024 -
Corticotropin-releasing hormone as a candidate biomarker for parkinsonian
disorders
Bárbara Fernandes Gomes, Atul Kumar, Nicholas J. Ashton, Sara Hall, Erik Stomrud, Ruben Smith, Henrik Zetterberg, Kaj Blennow, Niklas Mattsson-Carlgren, Oskar Hansson
BRAIN COMMUNICATIONS - 2024 -
Glial reactivity is linked to synaptic dysfunction across the aging and Alzheimer's disease
spectrum.
Tharick Pascoal, Francieli Rohden, Pamela Ferreira, Bruna Bellaver, João Pedro Ferrari-Souza, Cristiano Aguzzoli, Carolina Soares, Sarah Abbas, Hussein Zalzale, Guilherme Povala, Firoza Lussier, Douglas Leffa, Guilherme Bauer-Negrini, Nesrine Rahmouni, Cécile Tissot, Joseph Therriault Therriault, Stijn Servaes, Jenna Stevenson, Andrea L Benedet, Nicholas J. Ashton, Thomas Karikari, Dana Tudorascu, Henrik Zetterberg, Kaj Blennow, Eduardo Zimmer, Diogo Souza, Pedro Rosa-Neto
Research square - 2024 -
Plasma p-tau212 as a biomarker of sporadic and Down Syndrome Alzheimer's
disease.
Przemysław R Kac, Daniel Alcolea, Laia Montoliu-Gaya, Susana Fernández, Juan Lantero Rodriguez, Lucía Maure, Fernando Gonzalez-Ortiz, Bessy Benejam, Michael Turton, Isabel Barroeta, Peter Harrison, Laura Videla, Nicholas J. Ashton, Alberto Lleó, Henrik Zetterberg, María Carmona-Iragui, Thomas Karikari, Juan Fortea, Kaj Blennow
medRxiv : the preprint server for health sciences - 2024 -
A machine learning-based prediction of tau load and distribution in Alzheimer's disease using plasma, MRI and clinical
variables.
Linda Karlsson, Jacob Vogel, Ida Arvidsson, Kalle Åström, Olof Strandberg, Jakob Seidlitz, Richard A I Bethlehem, Erik Stomrud, Rik Ossenkoppele, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Sebastian Palmqvist, Ruben Smith, Shorena Janelidze, Renaud La Joie, Gil D Rabinovici, Alexa Pichet Binette, Niklas Mattsson-Carlgren, Oskar Hansson
medRxiv : the preprint server for health sciences - 2024 -
Timing of changes in Alzheimer's disease plasma biomarkers as assessed by amyloid and tau PET
clocks.
Marta Milà-Alomà, Duygu Tosun, Suzanne E Schindler, Zachary Hausle, Yan Li, Kellen K Petersen, Jeffrey L Dage, Lei Du-Cuny, Ziad S Saad, Benjamin Saef, Gallen Triana-Baltzer, David L Raunig, Janaky Coomaraswamy, Michael Baratta, Emily A Meyers, Yulia Mordashova, Carrie E Rubel, Kyle Ferber, Hartmuth Kolb, Nicholas J. Ashton, Henrik Zetterberg, Erin G Rosenbaugh, Martin Sabandal, Leslie M Shaw, Anthony W Bannon, William Z Potter
medRxiv : the preprint server for health sciences - 2024 -
Elevated plasma p-tau231 is associated with reduced generalization and medial temporal lobe dynamic network flexibility among healthy older African
Americans
Miray Budak, Bernadette A. Fausto, Zuzanna Osiecka, Mustafa Sheikh, Robert Perna, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Patricia Fitzgerald-Bocarsly, Mark A. Gluck
ALZHEIMERS RESEARCH & THERAPY - 2024 -
Circulating medium- and long-chain acylcarnitines are associated with plasma P-tau181 in cognitively normal older
adults
Tahmida Sharmin, Pratishtha Chatterjee, James D. Doecke, Nicholas J. Ashton, Kevin Huynh, Steve Pedrini, Hamid R. Sohrabi, Benjamin Heng, Shaun Eslick, Henrik Zetterberg, Kaj Blennow, Manohar Garg, Ralph N. Martins
JOURNAL OF NEUROCHEMISTRY - 2024 -
Identification of late-stage tau accumulation using plasma
phospho-tau217
Marcel S. Woo, Joseph Therriault, Erin M. Jonaitis, Rachael Wilson, Rebecca E. Langhough, Nesrine Rahmouni, Andréa Lessa Benedet, Nicholas J. Ashton, Cecile Tissot, Juan Lantero Rodriguez, Arthur C. Macedo, Stijn Servaes, Yi-Ting Wang, Jaime Fernandez Arias, Seyyed Ali Hosseini, Tobey J. Betthauser, Firoza Z. Lussier, Robert Hopewell, Gallen Triana-Baltzer, Hartmuth C. Kolb, Andreas Jeromin, Eliane Kobayashi, Gassan Massarweh, Manuel A. Friese, Jesse Klostranec, Paolo Vilali, Tharick A. Pascoal, Serge Gauthier, Henrik Zetterberg, Kaj Blennow, Sterling C. Johnson, Pedro Rosa-Neto
EBIOMEDICINE - 2024 -
Head-to-head comparison of leading blood tests for Alzheimer's disease
pathology
Suzanne E. Schindler, Kellen K. Petersen, Benjamin Saef, Duygu Tosun, Leslie M. Shaw, Henrik Zetterberg, Jeffrey L. Dage, Kyle Ferber, Gallen Triana-Baltzer, Lei Du-Cuny, Yan Li, Janaky Coomaraswamy, Michael Baratta, Yulia Mordashova, Ziad S. Saad, David L. Raunig, Nicholas J. Ashton, Emily A. Meyers, Carrie E. Rubel, Erin G. Rosenbaugh, Anthony W. Bannon, William Z. Potter
ALZHEIMERS & DEMENTIA - 2024 -
Clinical and research application of fluid bio markers in autosomal dominant Alzheimer's disease and Down
syndrome
Maria Carmona-Iragui, Antoinette O 'Connor, Jorge Llibre-Guerra, Patrick Lao, Nicholas J. Ashton, Juan Fortea, Raquel Sanchez-Valle
EBIOMEDICINE - 2024 -
Examination of plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in former elite American football
players
Annalise E. Miner, Jenna R. Groh, Yorghos Tripodis, Charles H. Adler, Laura J. Balcer, Charles Bernick, Henrik Zetterberg, Kaj Blennow, Elaine Peskind, Nicholas J. Ashton, Charles E. Gaudet, Brett Martin, Joseph N. Palmisano, Sarah J. Banks, William B. Barr, Jennifer V. Wethe, Robert C. Cantu, David W. Dodick, Douglas I. Katz, Jesse Mez, Suzan van Amerongen, Jeffrey L. Cummings, Martha E. Shenton, Eric M. Reiman, Robert A. Stern, Michael L. Alosco
ALZHEIMERS & DEMENTIA - 2024 -
A randomized, placebo-controlled trial of purified anthocyanins on cognitive function in individuals at elevated risk for dementia: Analysis of inflammatory biomarkers toward personalized
interventions
Miguel German Borda, George E. Barreto, Jonathan Patricio Baldera, Chiara de Lucia, Khadija Khalifa, Anne Katrine Bergland, Ilaria Pola, Felipe Botero-Rodriguez, Richard C. Siow, Miia Kivipelto, Henrik Zetterberg, Nicholas J. Ashton, Clive Ballard, Dag Aarsland
EXPERIMENTAL GERONTOLOGY - 2024 -
Plasma NfL, GFAP, amyloid, and p-tau species as Prognostic biomarkers in Parkinson's
disease
Andrea Pilotto, Nicholas J. Ashton, Alessandro Lupini, Beatrice Battaglio, Cinzia Zatti, Chiara Trasciatti, Stefano Gipponi, Elisabetta Cottini, Ilaria Grossi, Alessandro Salvi, Giuseppina de Petro, Marina Pizzi, Antonio Canale, Kaj Blennow, Henrik Zetterberg, Alessandro Padovani
JOURNAL OF NEUROLOGY - 2024 -
Plasma p-tau181 and amyloid markers in Alzheimer's disease: A comparison between Lumipulse and
SIMOA
Virginia Quaresima, Andrea Pilotto, Chiara Trasciatti, Chiara Tolassi, Marta Parigi, Diego Bertoli, Cristina Mordenti, Alice Galli, Andrea Rizzardi, Salvatore Caratozzolo, Alberto Benussi, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Silvia Giliani, Duilio Brugnoni, Alessandro Padovani
NEUROBIOLOGY OF AGING - 2024 -
Association of Plasma Amyloid, P-Tau, GFAP, and NfL With CSF, Clinical, and Cognitive Features in Patients With Dementia With Lewy
Bodies
Katharina Bolsewig, Annemartijn A. J. M. van Unnik, Elena R. Blujdea, Maria C. Gonzalez, Nicholas J. Ashton, Dag Aarsland, Henrik Zetterberg, Alessandro Padovani, Laura Bonanni, Brit Mollenhauer, Sebastian Schade, Rik Vandenberghe, Koen Poesen, Milica G. Kramberger, Claire Paquet, Olivier Bousiges, Benjamin Cretin, Eline A. J. Willemse, Charlotte E. Teunissen, Afina W. Lemstra
NEUROLOGY - 2024 -
Blood biomarkers of neurodegeneration associate differently with amyloid deposition, medial temporal atrophy, and cerebrovascular changes in APOE ε4-enriched cognitively unimpaired
elderly
Mikko Koivumäki, Laura Ekblad, Juan Lantero Rodriguez, Nicholas J. Ashton, Thomas Karikari, Semi Helin, Riitta Parkkola, Jyrki Lötjönen, Henrik Zetterberg, Kaj Blennow, Juha O. Rinne, Anniina Snellman
Alzheimer's Research and Therapy - 2024 -
Blood-based biomarkers in Alzheimer's disease - moving towards a new era of
diagnostics
Burak Arslan, Henrik Zetterberg, Nicholas J. Ashton
CLINICAL CHEMISTRY AND LABORATORY MEDICINE - 2024 -
Comparison of plasma and neuroimaging biomarkers to predict cognitive decline in non-demented memory clinic
patients
Augusto J. Mendes, Federica Ribaldi, Aurelien Lathuiliere, Nicholas J. Ashton, Henrik Zetterberg, Marc Abramowicz, Max Scheffler, Frédéric Assal, Valentina Garibotto, Kaj Blennow, Giovanni B. Frisoni
Alzheimer's Research and Therapy - 2024 -
Biomarkers of tau phosphorylation state are associated with the clinical course of multiple
sclerosis
Andreja Emersic, Thomas Karikari, Przemyslaw R. Kac, Fernando Gonzalez-Ortiz, Maciej Dulewicz, Nicholas J. Ashton, Gregor Brecl Jakob, Alenka Horvat Ledinek, Jörg Hanrieder, Henrik Zetterberg, Uros Rot, Sasa Cucnik, Kaj Blennow
MULTIPLE SCLEROSIS AND RELATED DISORDERS - 2024 -
Plasma Phosphorylated Tau 217 and Aβ42/40 to Predict Early Brain Aβ Accumulation in People Without Cognitive
Impairment
Shorena Janelidze, Nicolas R. Barthelemy, Gemma Salvado, Suzanne E. Schindler, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Joel B. Braunstein, Vitaliy Ovod, James G. Bollinger, Yingxin He, Yan Li, Cyrus A. Raji, John C. Morris, David M. Holtzman, Nicholas J. Ashton, Kaj Blennow, Erik Stomrud, Randall J. Bateman, Oskar Hansson
JAMA NEUROLOGY - 2024 -
Plasma pTau181 and pTau217 predict asymptomatic amyloid accumulation equally well as amyloid
PET
Steffi De Meyer, Jolien M. Schaeverbeke, Emma S. Luckett, Mariska Reinartz, Elena R. Blujdea, Isabelle Cleynen, Patrick Dupont, Koen Van Laere, Jeroen Vanbrabant, Erik Stoops, Eugeen Vanmechelen, Guglielmo Di Molfetta, Henrik Zetterberg, Nicholas J. Ashton, Charlotte E. Teunissen, Koen Poesen, Rik Vandenberghe
BRAIN COMMUNICATIONS - 2024 -
The Taxonomy of Subjective Cognitive Decline: Proposal and First Clinical Evidence from the Geneva Memory Clinic
Cohort
Federica Ribaldi, Rafael Palomo, Daniele Altomare, Max Scheffler, Frederic Assal, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Marc Abramowicz, Valentina Garibotto, Christian Chicherio, Giovanni B. Frisoni
NEURODEGENERATIVE DISEASES - 2024 -
CSF glial biomarkers are associated with cognition in individuals at risk of Alzheimer's
disease
Noelle Warmenhoven, Gonzalo Sanchez-Benavides, Armand Gonzalez-Escalante, Marta Mila-Aloma, Mahnaz Shekari, David Lopez-Martos, Paula Ortiz-Romero, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Carolina Minguillon, Juan Domingo Gispert, Natalia Vilor-Tejedor, Eider Arenaza-Urquijo, Eleni Palpatzis, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Marc Suarez-Calvet, Oriol Grau-Rivera
ALZHEIMERS & DEMENTIA - 2024 -
Longitudinal plasma phosphorylated-tau217 and other related biomarkers in a non-demented Alzheimer's risk-enhanced
sample
Lianlian Du, Rebecca E. Langhough, Rachael E. Wilson, Ramiro Eduardo Rea Reyes, Bruce P. Hermann, Erin M. Jonaitis, Tobey J. Betthauser, Nathaniel A. Chin, Bradley Christian, Lauren Chaby, Andreas Jeromin, Guglielmo Di Molfetta, Wagner Scheeren Brum, Burak Arslan, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Sterling C. Johnson
ALZHEIMERS & DEMENTIA - 2024 -
Microstructural associations between locus coeruleus, cortical, and subcortical regions are modulated by astrocyte reactivity: a 7T MRI adult lifespan
study
Elise Beckers, Maxime Van Egroo, Nicholas J. Ashton, Kaj Blennow, Gilles Vandewalle, Henrik Zetterberg, Benedikt A. Poser, Heidi I. L. Jacobs
CEREBRAL CORTEX - 2024 -
Effects of time of the day at sampling on CSF and plasma levels of Alzheimer' disease
biomarkers
Anna Orduna Dolado, Erik Stomrud, Nicholas J. Ashton, Johanna Nilsson, Clara Quijano-Rubio, Alexander Jethwa, Wagner Scheeren Brum, Ann Brinkmalm-Westman, Henrik Zetterberg, Kaj Blennow, Shorena Janelidze, Oskar Hansson
ALZHEIMERS RESEARCH & THERAPY - 2024 -
Biomarkers of Neurobiologic Recovery in Adults With Sport-Related
Concussion
William T. O'Brien, Gershon Spitz, Becca Xie, Brendan P. Major, Steven Mutimer, Lauren P. Giesler, Jesse Bain, Lauren J. Evans, Beatriz Duarte Martins, Stefan Piantella, Afizu Alhassan, Shelby Brady, David Cappellari, Vincenzo Somma, Thomas McColl, Georgia F. Symons, Tenae Gore, Matthew Sun, Timothy Kuek, Seamus Horan, Michael Bei, Jennie L. Ponsford, Catherine Willmott, Jonathan Reyes, Nicholas J. Ashton, Henrik Zetterberg, Biswadev Mitra, Terence J. O'Brien, Sandy R. Shultz, Stuart J. McDonald
JAMA NETWORK OPEN - 2024 -
Plasma biomarkers increase diagnostic confidence in patients with Alzheimer's disease or frontotemporal lobar
degeneration.
Daniele Altomare, Ilenia Libri, Antonella Alberici, Jasmine Rivolta, Alessandro Padovani, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Barbara Borroni
Alzheimer's research & therapy - 2024 -
Personalized whole-brain neural mass models reveal combined Aβ and tau hyperexcitable influences in Alzheimer's
disease.
Lazaro M Sanchez-Rodriguez, Gleb Bezgin, Felix Carbonell, Joseph Therriault, Jaime Fernandez-Arias, Stijn Servaes, Nesrine Rahmouni, Cécile Tissot, Jenna Stevenson, Thomas K Karikari, Nicholas J. Ashton, Andréa Lessa Benedet, Henrik Zetterberg, Kaj Blennow, Gallen Triana-Baltzer, Hartmuth C Kolb, Pedro Rosa-Neto, Yasser Iturria-Medina
Communications biology - 2024 -
Plasma Phosphorylated Tau 231 Increases at One-Year Intervals in Cognitively Unimpaired
Subjects
Francisco Martinez-Dubarbie, Sara Lopez-Garcia, Carmen Lage, Guglielmo Di Molfetta, Marta Fernandez-Matarrubia, Ana Pozueta-Cantudo, Maria Garcia-Martinez, Andrea Corrales-Pardo, Maria Bravo, Julio Jimenez-Bonilla, Remedios Quirce, Enrique Marco de Lucas, Marta Drake-Perez, Diana Tordesillas, Marcos Lopez-Hoyos, Juan Irure-Ventura, Elizabeth Valeriano-Lorenzo, Kaj Blennow, Nicholas J. Ashton, Henrik Zetterberg, Eloy Rodriguez-Rodriguez, Pascual Sanchez-Juan
JOURNAL OF ALZHEIMERS DISEASE - 2024 -
Sex-specific modulation of amyloid-β on tau phosphorylation underlies faster tangle accumulation in
females
Yi-Ting Wang, Joseph Therriault, Stijn Servaes, Cécile Tissot, Nesrine Rahmouni, Arthur Cassa Macedo, Jaime Fernandez-Arias, Sulantha S Mathotaarachchi, Andréa Lessa Benedet, Jenna Stevenson, Nicholas J. Ashton, Firoza Z Lussier, Tharick A Pascoal, Henrik Zetterberg, Maria Natasha Rajah, Kaj Blennow, Serge Gauthier, Pedro Rosa-Neto
Brain : a journal of neurology - 2024 -
Association of plasma GFAP with elevated brain amyloid is dependent on severity of white matter lesions in an Asian cognitively impaired
cohort.
Joyce R Chong, Yuek Ling Chai, Amelia T Y Yam, Saima Hilal, Henri Vrooman, Narayanaswamy Venketasubramanian, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Christopher P Chen, Mitchell K P Lai
Alzheimer's & dementia (Amsterdam, Netherlands) - 2024 -
Plasma glial fibrillary acidic protein and tau: predictors of neurological outcome after cardiac
arrest.
Isabelle Arctaedius, Helena Levin, Bergthóra Thorgeirsdóttir, Marion Moseby-Knappe, Tobias Cronberg, Martin Annborn, Niklas Nielsen, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Attila Frigyesi, Hans Friberg, Anna Lybeck, Niklas Mattsson-Carlgren
Critical care (London, England) - 2024 -
Plasma p-tau212 antemortem diagnostic performance and prediction of autopsy verification of Alzheimer's disease
neuropathology.
Przemyslaw R. Kac, Fernando Gonzalez-Ortiz, Andreja Emeršič, Maciej Dulewicz, Srinivas Koutarapu, Michael Turton, Yang An, Denis Smirnov, Agnieszka Kulczyńska-Przybik, Vijay R Varma, Nicholas J. Ashton, Laia Montoliu-Gaya, Elena Camporesi, Izabela Winkel, Bogusław Paradowski, Abhay Moghekar, Juan C Troncoso, Tammaryn Lashley, Gunnar Brinkmalm, Susan M Resnick, Barbara Mroczko, Hlin Kvartsberg, Milica Gregorič Kramberger, Jörg Hanrieder, Saša Čučnik, Peter Harrison, Henrik Zetterberg, Piotr Lewczuk, Madhav Thambisetty, Uroš Rot, Douglas Galasko, Kaj Blennow, Thomas Karikari
Nature communications - 2024 -
A blood-based biomarker workflow for optimal tau-PET referral in memory clinic
settings.
Wagner Scheeren Brum, Nicholas C Cullen, Joseph Therriault, Shorena Janelidze, Nesrine Rahmouni, Jenna Stevenson, Stijn Servaes, Andréa Lessa Benedet, Eduardo R Zimmer, Erik Stomrud, Sebastian Palmqvist, Henrik Zetterberg, Giovanni B Frisoni, Nicholas J. Ashton, Kaj Blennow, Niklas Mattsson-Carlgren, Pedro Rosa-Neto, Oskar Hansson
Nature Communications - 2024 -
Comparison of two plasma p-tau217 assays to detect and monitor Alzheimer's
pathology.
Joseph Therriault, Nicholas J. Ashton, Ilaria Pola, Gallen Triana-Baltzer, Wagner Scheeren Brum, Guglielmo Di Molfetta, Burak Arslan, Nesrine Rahmouni, Cecile Tissot, Stijn Servaes, Jenna Stevenson, Arthur Cassa Macedo, Tharick Ali Pascoal, Hartmuth Christian Kolb, Andreas Jeromin, Kaj Blennow, Henrik Zetterberg, Pedro Rosa-Neto, Andréa Lessa Benedet
EBioMedicine - 2024 -
Repetitive head injuries in German American football players do not change blood-based biomarker candidates for CTE during a single
season
Theres Bastgen, Janis Evers, Christiane Oedekoven, Caroline Weide, Lars Herzog, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Alexandra Albus, Natasha Vidovic, Oliver Kraff, Cornelius Deuschl, Richard Dodel, J. Alexander Ross
NEUROLOGICAL RESEARCH AND PRACTICE - 2024 -
Inflammatory biomarkers for neurobehavioral dysregulation in former American football players: findings from the DIAGNOSE CTE Research
Project
Suzan van Amerongen, Surya V. Pulukuri, Fatima Tuz-Zahra, Yorghos Tripodis, Jonathan D. Cherry, Charles Bernick, Yonas E. Geda, Jennifer V. Wethe, Douglas I. Katz, Michael L. Alosco, Charles H. Adler, Laura J. Balcer, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Daniel H. Daneshvar, Elizabeth A. Colasurdo, Jeffrey J. Iliff, Gail Li, Elaine R. Peskind, Martha E. Shenton, Eric M. Reiman, Jeffrey L. Cummings, Robert A. Stern
JOURNAL OF NEUROINFLAMMATION - 2024 -
Biomarker-based staging of Alzheimer disease: rationale and clinical
applications.
Joseph Therriault, Suzanne E Schindler, Gemma Salvadó, Tharick A Pascoal, Andréa Lessa Benedet, Nicholas J. Ashton, Thomas Karikari, Liana Apostolova, Melissa E Murray, Inge Verberk, Jacob W Vogel, Renaud La Joie, Serge Gauthier, Charlotte Teunissen, Gil D Rabinovici, Henrik Zetterberg, Randall J Bateman, Philip Scheltens, Kaj Blennow, Reisa Sperling, Oskar Hansson, Clifford R Jack, Pedro Rosa-Neto
Nature reviews. Neurology - 2024 -
Biomarkers of Alzheimer's disease and neurodegeneration in dried blood spots-A new collection method for remote
settings
Hanna Huber, Kaj Blennow, Henrik Zetterberg, Merce Boada, Andreas Jeromin, Haley Weninger, Raul Nunez-Llaves, Nuria Aguilera, Maribel Ramis, Joel Simrén, Johanna Nilsson, Juan Lantero Rodriguez, Adelina Orellana, Fernando Garcia-Gutierrez, Xavier Morato, Nicholas J. Ashton, Laia Montoliu-Gaya
ALZHEIMERS & DEMENTIA - 2024 -
Head-to-head study of diagnostic accuracy of plasma and cerebrospinal fluid p-tau217 versus p-tau181 and p-tau231 in a memory clinic
cohort
Augusto J. Mendes, Federica Ribaldi, Aurelien Lathuiliere, Nicholas J. Ashton, Shorena Janelidze, Henrik Zetterberg, Max Scheffler, Frederic Assal, Valentina Garibotto, Kaj Blennow, Oskar Hansson, Giovanni B. Frisoni
JOURNAL OF NEUROLOGY - 2024 -
Optimal blood tau species for the detection of Alzheimer's disease neuropathology: an immunoprecipitation mass spectrometry and autopsy
study.
Laia Montoliu-Gaya, Michael L Alosco, Eukyung Yhang, Yorghos Tripodis, Daniel Sconzo, Madeline Ally, Lana Grötschel, Nicholas J. Ashton, Juan Lantero Rodriguez, Mathias Sauer, Bárbara Fernandes Gomes, Johanna Nilsson, Gunnar Brinkmalm, Michael A Sugarman, Hugo J Aparicio, Brett Martin, Joseph N Palmisano, Eric G Steinberg, Irene Simkin, Katherine W Turk, Andrew E Budson, Rhoda Au, Lindsay Farrer, Gyungah R Jun, Neil W Kowall, Robert A Stern, Lee E Goldstein, Wei Qiao Qiu, Jesse Mez, Bertrand Russell Huber, Victor E Alvarez, Ann C McKee, Henrik Zetterberg, Johan Gobom, Thor D Stein, Kaj Blennow
Acta neuropathologica - 2024 -
A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's
disease.
Fernando Gonzalez-Ortiz, Pamela C L Ferreira, Armand González-Escalante, Laia Montoliu-Gaya, Paula Ortiz-Romero, Przemyslaw R. Kac, Michael Turton, Hlin Kvartsberg, Nicholas J. Ashton, Henrik Zetterberg, Peter Harrison, Bruna Bellaver, Guilherme Povala, Victor L Villemagne, Tharick A Pascoal, Mary Ganguli, Anne D Cohen, Carolina Minguillon, Jose Contador, Marc Suárez-Calvet, Thomas Karikari, Kaj Blennow
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2024 -
Effect of Neprilysin Inhibition on Alzheimer Disease Plasma Biomarkers: A Secondary Analysis of a Randomized Clinical
Trial
Wagner Scheeren Brum, Kieran F Docherty, Nicholas J. Ashton, Henrik Zetterberg, Oskar Hansson, John J V McMurray, Kaj Blennow
JAMA neurology - 2024 -
Plasma Biomarker Strategy for Selecting Patients With Alzheimer Disease for Antiamyloid
Immunotherapies
Niklas Mattsson-Carlgren, Lyduine E Collij, Erik Stomrud, Alexa Pichet Binette, Rik Ossenkoppele, Ruben Smith, Linda Karlsson, Juan Lantero Rodriguez, Anniina Snellman, Olof Strandberg, Sebastian Palmqvist, Nicholas J. Ashton, Kaj Blennow, Shorena Janelidze, Oskar Hansson
JAMA neurology - 2024 -
Plasma GFAP and its association with disease severity in Huntington's
disease.
Kübra Tan, Melanie Alpaugh, Nicholas J. Ashton, Sylvain Chouinard, Roger A Barker, Kaj Blennow, Henrik Zetterberg, Francesca Cicchetti, Andréa Lessa Benedet
Journal of neurology - 2024 -
Plasma pTau-217 and N-terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid-β positive
individuals
M. S. Woo, C. Tissot, Juan Lantero Rodriguez, Anniina Snellman, J. Therriault, N. Rahmouni, A. C. Macedo, S. Servaes, Y. T. Wang, J. F. Arias, S. A. Hosseini, M. Chamoun, F. Z. Lussier, Andréa Lessa Benedet, Nicholas J. Ashton, T. K. Karikari, G. Triana-Baltzer, H. C. Kolb, J. Stevenson, C. Mayer, E. Kobayashi, G. Massarweh, M. A. Friese, T. A. Pascoal, S. Gauthier, Henrik Zetterberg, Kaj Blennow, P. Rosa-Neto
Alzheimers & Dementia - 2024 -
CT-based volumetric measures obtained through deep learning: Association with biomarkers of
neurodegeneration
Meera Srikrishna, Nicholas J. Ashton, Alexis Moscoso Rial, J. B. Pereira, Rolf A. Heckemann, D. van Westen, Giovanni Volpe, Joel Simrén, Anna Zettergren, Silke Kern, L. O. Wahlund, B. Gyanwali, S. Hilal, J. C. Ruifen, Henrik Zetterberg, Kaj Blennow, E. Westman, C. S. P. Chen, Ingmar Skoog, Michael Schöll
Alzheimers & Dementia - 2024 -
Plasma p-tau181 as an outcome and predictor of multidomain intervention effects: a secondary analysis of a randomised, controlled, dementia prevention
trial
Nicola Coley, Henrik Zetterberg, Christelle Cantet, Sophie Guyonnet, Nicholas J. Ashton, Bruno Vellas, Kaj Blennow, Sandrine Andrieu, Isabelle Carrié, Lauréane Brigitte, Catherine Faisant, Françoise Lala, Julien Delrieu, Hélène Villars, Emeline Combrouze, Carole Badufle, Audrey Zueras, Christophe Morin, Gabor Abellan Van Kan, Charlotte Dupuy, Yves Rolland, Céline Caillaud, Pierre Jean Ousset, Sherry Willis, Sylvie Belleville, Brigitte Gilbert, Francine Fontaine, Jean François Dartigues, Isabelle Marcet, Fleur Delva, Alexandra Foubert, Sandrine Cerda, Marie Noëlle Cuffi, Corinne Costes, Olivier Rouaud, Patrick Manckoundia, Valérie Quipourt, Sophie Marilier, Evelyne Franon, Lawrence Bories, Marie Laure Pader, Marie France Basset, Bruno Lapoujade, Valérie Faure, Michael Li Yung Tong, Christine Malick-Loiseau, Evelyne Cazaban-Campistron, Françoise Desclaux, Colette Blatge, Thierry Dantoine, Cécile Laubarie-Mouret, Isabelle Saulnier, Jean Pierre Clément, Marie Agnès Picat, Laurence Bernard-Bourzeix, Stéphanie Willebois, Iléana Désormais, Noëlle Cardinaud, Marc Bonnefoy, Pierre Livet, Pascale Rebaudet, Claire Gédéon, Catherine Burdet, Flavien Terracol, Alain Pesce, Stéphanie Roth, Sylvie Chaillou, Sandrine Louchart, Kristel Sudres, Nicolas Lebrun, Nadège Barro-Belaygues, Jacques Touchon, Karim Bennys, Audrey Gabelle, Aurélia Romano, Lynda Touati, Cécilia Marelli, Cécile Pays, Philippe Robert, Franck Le Duff, Claire Gervais, Sébastien Gonfrier, Yannick Gasnier, Serge Bordes, Danièle Begorre, Christian Carpuat, Khaled Khales, Jean François Lefebvre, Samira Misbah El Idrissi, Pierre Skolil, Jean Pierre Salles, Carole Dufouil, Stéphane Lehéricy, Marie Chupin, Jean François Mangin, Ali Bouhayia, Michèle Allard, Frédéric Ricolfi, Dominique Dubois, Marie Paule Bonceour Martel
The Lancet Healthy Longevity - 2024 -
Biological variation estimates of Alzheimer's disease plasma biomarkers in healthy
individuals
Wagner Scheeren Brum, Nicholas J. Ashton, Joel Simrén, Guiglielmo di Molfetta, Thomas Karikari, Andréa Lessa Benedet, Eduardo R. Zimmer, Juan Lantero Rodriguez, Laia Montoliu-Gaya, Andreas Jeromin, Aasne K. Aarsand, William A. Bartlett, Pilar Fernández Calle, Abdurrahman Coşkun, Jorge Díaz–Garzón, Niels Jonker, Henrik Zetterberg, Sverre Sandberg, Anna Carobene, Kaj Blennow
Alzheimer's and Dementia - 2024 -
Plasma N-terminal containing tau fragments (NTA-tau): a biomarker of tau deposition in Alzheimer's
Disease
Juan Lantero Rodriguez, Gemma Salvado, Anniina Snellman, Laia Montoliu-Gaya, Wagner Scheeren Brum, Andréa Lessa Benedet, Niklas Mattsson-Carlgren, Pontus Tideman, Shorena Janelidze, Sebastian Palmqvist, Erik Stomrud, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Oskar Hansson
MOLECULAR NEURODEGENERATION - 2024 -
Day-to-day sleep variability with Alzheimer's biomarkers in at-risk
elderly
Andree-Ann Baril, Cynthia Picard, Anne Labonte, Erlan Sanchez, Catherine Duclos, Bery Mohammediyan, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, John C. S. Breitner, Sylvia Villeneuve, Judes Poirier
ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING - 2024 -
Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease
Pathology
Nicholas J. Ashton, Wagner Scheeren Brum, Guglielmo Di Molfetta, Andréa Lessa Benedet, Burak Arslan, Erin Jonaitis, Rebecca E. Langhough, Karly Cody, Rachael Wilson, Cynthia M. Carlsson, Eugeen Vanmechelen, Laia Montoliu-Gaya, Juan Lantero Rodriguez, Nesrine Rahmouni, Cecile Tissot, Jenna Stevenson, Stijn Servaes, Joseph Therriault, Tharick Pascoal, Alberto Lleo, Daniel Alcolea, Juan Fortea, Pedro Rosa-Neto, Sterling Johnson, Andreas Jeromin, Kaj Blennow, Henrik Zetterberg
JAMA NEUROLOGY - 2024 -
Comparison of immunoassay- with mass spectrometry-derived p-tau quantification for the detection of Alzheimer’s disease
pathology
Joseph Therriault, Marcel S. Woo, Gemma Salvadó, Johan Gobom, Thomas Karikari, Shorena Janelidze, Stijn Servaes, Nesrine Rahmouni, Cécile Tissot, Nicholas J. Ashton, Andréa Lessa Benedet, Laia Montoliu-Gaya, Arthur C. Macedo, Firoza Z. Lussier, Jenna Stevenson, Paolo Vitali, Manuel A. Friese, Gassan Massarweh, Jean Paul Soucy, Tharick A. Pascoal, Erik Stomrud, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Serge Gauthier, Henrik Zetterberg, Oskar Hansson, Kaj Blennow, Pedro Rosa-Neto
Molecular Neurodegeneration - 2024 -
CSF p-tau205: a biomarker of tau pathology in Alzheimer's
disease.
Juan Lantero Rodriguez, Laia Montoliu-Gaya, Andréa Lessa Benedet, Agathe Vrillon, Julien Dumurgier, Emmanuel Cognat, Wagner Scheeren Brum, Nesrine Rahmouni, Jenna Stevenson, Stijn Servaes, Joseph Therriault, Bruno Becker, Gunnar Brinkmalm, Anniina Snellman, Hanna Huber, Hlin Kvartsberg, Nicholas J. Ashton, Henrik Zetterberg, Claire Paquet, Pedro Rosa-Neto, Kaj Blennow
Acta neuropathologica - 2024 -
Astrocyte reactivity influences the association of amyloid-β and tau biomarkers in preclinical Alzheimer's
disease.
Tharick Pascoal, Bruna Bellaver, Guilherme Povala, Pamela Ferreira, João Pedro Ferrari-Souza, Douglas Leffa, Firoza Lussier, Andréa Lessa Benedet, Nicholas J. Ashton, Gallen Triana-Baltzerz, Hartmuth Kolbzh, Cèile Tissot, Joseph Therriault, Stijn Servaes, Jenna Stevenson, Nesrine Rahmouni, Oscar Lopez, Dana Tudorascu, Victor Villemagne, Milos Ikonomovic, Serge Gauthier, Eduardo Zimmer, Henrik Zetterberg, Kaj Blennow, Howard Aizenstein, William Klunk, Beth Snitz, Pauline Maki, Rebecca Thurston, Ann Cohen, Mary Ganguli, Thomas Karikari, Pedro Rosa-Neto
Research square - 2023 -
Diagnostic accuracy of the plasma ALZpath pTau217 immunoassay to identify Alzheimer's disease
pathology.
Nicholas J. Ashton, Wagner Scheeren Brum, Guglielmo Di Molfetta, Andréa Lessa Benedet, Burak Arslan, Erin Jonatis, Rebecca E Langhough, Karly Cody, Rachael Wilson, Cynthia M Carlsson, Eugeen Vanmechelen, Laia Montoliu-Gaya, Juan Lantero Rodriguez, Nesrine Rahmouni, Cecile Tissot, Jenna Stevenson, Stijn Servaes, Joseph Therriault, Tharick Pascoal, Alberto Lleó, Daniel Alcolea, Juan Fortea, Pedro Rosa-Neto, Sterling Johnson, Andreas Jeromin, Kaj Blennow, Henrik Zetterberg
medRxiv : the preprint server for health sciences - 2023 -
Menopause hormone therapy significantly alters pathophysiological biomarkers of Alzheimer's
disease
D. Herman, V. Andrea, L. Pablo, L. Simone, Andréa Lessa Benedet, Nicholas J. Ashton, C. Enrica, Henrik Zetterberg, Kaj Blennow, V. Eugeen, H. Harald
Alzheimers & Dementia - 2023 -
Exploring semantic verbal fluency patterns and their relationship to age and Alzheimer's disease in adults with Down
syndrome.
Farah Mgaieth, R Asaad Baksh, Carla M Startin, Sarah Hamburg, Rosalyn Hithersay, Sarah Pape, Henrik Zetterberg, Nicholas J. Ashton, Miren Tamayo-Elizalde, Fedal Saini, Mina Idris, Andre Strydom
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2023 -
Prevalence and Clinical Implications of a β-Amyloid-Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer
Disease.
Pontus Erickson, Joel Simrén, Wagner Scheeren Brum, Gilda E Ennis, Gwendlyn Kollmorgen, Ivonne Suridjan, Rebecca Langhough, Erin M Jonaitis, Carol A Van Hulle, Tobey J Betthauser, Cynthia M Carlsson, Sanjay Asthana, Nicholas J. Ashton, Sterling C Johnson, Leslie M Shaw, Kaj Blennow, Ulf Andreasson, Barbara B Bendlin, Henrik Zetterberg
JAMA neurology - 2023 -
Longitudinal blood biomarker trajectories in preclinical Alzheimer's
disease
Y. Yakoub, Nicholas J. Ashton, C. Strikwerda-Brown, Laia Montoliu-Gaya, Thomas Karikari, Przemyslaw R. Kac, Fernando Gonzalez-Ortiz, J. Gallego-Rudolf, P. F. Meyer, F. St-Onge, Michael Schöll, J. P. Soucy, J. C. S. Breitner, Henrik Zetterberg, Kaj Blennow, J. Poirier, S. Villeneuve
Alzheimers & Dementia - 2023 -
Levels of Alzheimer's disease blood biomarkers are altered after food intake-A pilot intervention study in healthy
adults
Hanna Huber, Nicholas J. Ashton, A. Schieren, Laia Montoliu-Gaya, Guglielmo Di Molfetta, Wagner Scheeren Brum, Juan Lantero Rodriguez, Lana Grötschel, B. Stoffel-Wagner, M. Coenen, L. Weinhold, M. Schmid, Kaj Blennow, P. Stehle, Henrik Zetterberg, M. C. Simon
Alzheimers & Dementia - 2023 -
Plasma and CSF concentrations of N-terminal tau fragments associate with in vivo neurofibrillary tangle
burden
Juan Lantero Rodriguez, C. Tissot, Anniina Snellman, S. Servaes, Andréa Lessa Benedet, N. Rahmouni, Laia Montoliu-Gaya, J. Therriault, Wagner Scheeren Brum, J. Stevenson, F. Z. Lussier, G. Bezgin, A. C. Macedo, M. Chamoun, S. S. Mathotaarachi, T. A. Pascoal, Nicholas J. Ashton, Henrik Zetterberg, P. R. Neto, Kaj Blennow
Alzheimers & Dementia - 2023 -
Alzheimer Disease Blood Biomarkers in Patients With Out-of-Hospital Cardiac
Arrest
Nicholas J. Ashton, M. Moseby-Knappe, Andréa Lessa Benedet, Lana Grötschel, Juan Lantero Rodriguez, Thomas Karikari, C. Hassager, M. P. Wise, P. Stammet, J. Kjaergaard, H. Friberg, N. Nielsen, T. Cronberg, Henrik Zetterberg, Kaj Blennow
Jama Neurology - 2023 -
Astrocyte biomarkers GFAP and YKL-40 mediate early Alzheimer's disease
progression.
Wiesje Pelkmans, Mahnaz Shekari, Anna Brugulat-Serrat, Gonzalo Sánchez-Benavides, Carolina Minguillón, Karine Fauria, Jose Luis Molinuevo, Oriol Grau-Rivera, Armand González Escalante, Gwendlyn Kollmorgen, Margherita Carboni, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Marc Suarez-Calvet, Juan Domingo Gispert
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2023 -
A novel ultrasensitive assay for plasma p-tau217: performance in individuals with subjective cognitive decline and early Alzheimer's
disease.
Fernando Gonzalez-Ortiz, Pamela C L Ferreira, Armand Gonzalez, Laia Montoliu-Gaya, Paula Ortiz-Romero, Przemyslaw R. Kac, Michael Turton, Hlin Kvartsberg, Nicholas J. Ashton, Henrik Zetterberg, Peter Harrison, Bruna Bellaver, Guilherme Povala, Victor L Villemagne, Tharick A Pascoal, Mary Ganguli, Anne D Cohen, Carolina Miguillon, Jose Contador, Marc Suarez-Calvet, Thomas Karikari, Kaj Blennow
medRxiv : the preprint server for health sciences - 2023 -
Blood-brain barrier integrity impacts the use of plasma amyloid-beta as a proxy of brain amyloid-beta
pathology
B. Bellaver, A. Puig-Pijoan, J. P. Ferrari-Souza, D. T. Leffa, F. Z. Lussier, P. C. L. Ferreira, C. Tissot, G. Povala, J. Therriault, Andréa Lessa Benedet, Nicholas J. Ashton, S. Servaes, M. Chamoun, J. Stevenson, N. Rahmouni, M. Vermeiren, A. C. Macedo, A. Fernandez-Lebrero, G. Garcia-Escobar, I. Navalpotro-Gomez, O. Lopez, D. L. Tudorascu, A. Cohen, V. L. Villemagne, W. E. Klunk, S. Gauthier, E. R. Zimmer, Thomas Karikari, Kaj Blennow, Henrik Zetterberg, M. Suarez-Calvet, P. Rosa-Neto, T. A. Pascoal
Alzheimers & Dementia - 2023 -
Endocannabinoid System Biomarkers in Alzheimer's
Disease
Pamela C. L. Ferreira, Bruna Bellaver, Guilherme Povala, Wagner Scheeren Brum, Cecile Tissot, Atef Badji, Matthew E. Sloan, Andréa Lessa Benedet, Pedro Rosa-Neto, Nicholas J. Ashton, Tharick A. Pascoal, Antoine Leuzy, Eduardo R. Zimmer
CANNABIS AND CANNABINOID RESEARCH - 2023 -
APOEε4 potentiates amyloid β effects on longitudinal tau
pathology
J. P. Ferrari-Souza, B. Bellaver, P. C. L. Ferreira, Andréa Lessa Benedet, G. Povala, F. Z. Lussier, D. T. Leffa, J. Therriault, C. Tissot, C. Soares, Y. T. Wang, M. Chamoun, S. Servaes, A. C. Macedo, M. Vermeiren, G. Bezgin, M. S. Kang, J. Stevenson, N. Rahmouni, V. Pallen, N. M. Poltronetti, A. Cohen, O. L. Lopez, W. E. Klunk, J. P. Soucy, S. Gauthier, D. O. Souza, G. Triana-Baltzer, Z. S. Saad, H. C. Kolb, Thomas Karikari, V. L. Villemagne, D. L. Tudorascu, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, E. R. Zimmer, P. Rosa-Neto, T. A. Pascoal
Nature Aging - 2023 -
Blood beta-synuclein is related to amyloid PET positivity in memory clinic
patients
P. Oeckl, M. Bluma, M. Bucci, S. Halbgebauer, K. Chiotis, A. Sandebring-Matton, Nicholas J. Ashton, Guglielmo Di Molfetta, Lana Grötschel, M. Kivipelto, Kaj Blennow, Henrik Zetterberg, I. Savitcheva, A. Nordberg, M. Otto
Alzheimers & Dementia - 2023 -
Plasma and CSF biomarkers in a memory clinic: Head-to-head comparison of phosphorylated tau
immunoassays
Nicholas J. Ashton, A. Puig-Pijoan, M. Mila-Aloma, A. Fernandez-Lebrero, G. Garcia-Escobar, Fernando Gonzalez-Ortiz, Przemyslaw R. Kac, Wagner Scheeren Brum, Andréa Lessa Benedet, Juan Lantero Rodriguez, T. A. Day, J. Vanbrabant, E. Stoops, E. Vanmechelen, G. Triana-Baltzer, S. Moughadam, H. Kolb, P. Ortiz-Romero, Thomas Karikari, C. Minguillon, J. J. H. Sanchez, I. Navalpotro-Gomez, O. Grau-Rivera, R. M. Manero, V. Puente-Periz, R. de la Torre, J. Roquer, J. L. Dage, Henrik Zetterberg, Kaj Blennow, M. Suarez-Calvet
Alzheimers & Dementia - 2023 -
Longitudinal changes in Alzheimer's-related plasma biomarkers and brain
amyloid
M. Bilgel, Y. An, K. A. Walker, A. R. Moghekar, Nicholas J. Ashton, Przemyslaw R. Kac, Thomas Karikari, Kaj Blennow, Henrik Zetterberg, B. M. Jedynak, M. Thambisetty, L. Ferrucci, S. M. Resnick
Alzheimers & Dementia - 2023 -
Association of Choroid Plexus Volume With Serum Biomarkers, Clinical Features, and Disease Severity in Patients With Frontotemporal Lobar Degeneration
Spectrum
M. Assogna, E. Premi, S. Gazzina, A. Benussi, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, R. Gasparotti, A. Padovani, E. Tadayon, S. Romanella, G. Sprugnoli, A. Pascual-Leone, F. Di Lorenzo, G. Koch, B. Borroni, E. Santarnecchi
NEUROLOGY - 2023 -
Tracking reactive astrogliosis in autosomal dominant and sporadic Alzheimer's disease with multi-modal PET and plasma
GFAP
K. Chiotis, C. Johansson, E. Rodriguez-Vieitez, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, C. Graff, A. Nordberg
Molecular Neurodegeneration - 2023 -
A two-step workflow based on plasma p-tau217 to screen for amyloid β positivity with further confirmatory testing only in uncertain
cases
Wagner Scheeren Brum, N. C. Cullen, S. Janelidze, Nicholas J. Ashton, E. R. Zimmer, J. Therriault, Andréa Lessa Benedet, N. Rahmouni, C. Tissot, J. Stevenson, S. Servaes, G. Triana-Baltzer, H. C. Kolb, S. Palmqvist, E. Stomrud, P. Rosa-Neto, Kaj Blennow, O. Hansson
Nature Aging - 2023 -
Plasma p-tau231 and p-tau217 inform on tau tangles aggregation in cognitively impaired
individuals
P. C. L. Ferreira, J. Therriault, C. Tissot, J. P. Ferrari-Souza, Andréa Lessa Benedet, G. Povala, B. Bellaver, D. T. Leffa, W. S. Brum, F. Z. Lussier, G. Bezgin, S. Servaes, M. Vermeiren, A. C. Macedo, A. Cabrera, J. Stevenson, G. Triana-Baltzer, H. Kolb, N. Rahmouni, W. E. Klunk, O. L. Lopez, V. L. Villemagne, A. Cohen, D. L. Tudorascu, E. R. Zimmer, Thomas Karikari, Nicholas J. Ashton, Henrik Zetterberg, K. Blennow, S. Gauthier, P. Rosa-Neto, T. A. Pascoal
Alzheimers & Dementia - 2023 -
Profiling of plasma biomarkers in the context of memory assessment in a tertiary memory
clinic
M. Bucci, M. Bluma, I. Savitcheva, Nicholas J. Ashton, K. Chiotis, A. Matton, M. Kivipelto, Guglielmo Di Molfetta, Kaj Blennow, Henrik Zetterberg, A. Nordberg
Translational Psychiatry - 2023 -
Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical
Trials
P. C. L. Ferreira, J. P. Ferrari-Souza, C. Tissot, B. Bellaver, D. T. Leffa, F. Lussier, G. Povala, J. Therriault, Andréa Lessa Benedet, Nicholas J. Ashton, A. D. Cohen, O. L. Lopez, D. L. Tudorascu, W. E. Klunk, J. P. Soucy, S. Gauthier, V. Villemagne, Henrik Zetterberg, Kaj Blennow, P. Rosa-Neto, E. R. Zimmer, Thomas Karikari, T. A. Pascoal, Neuroimaging Alzheimers Dis
NEUROLOGY - 2023 -
Astrocyte reactivity influences amyloid-beta effects on tau pathology in preclinical Alzheimer's
disease
B. Bellaver, G. Povala, P. C. L. Ferreira, J. P. Ferrari-Souza, D. T. Leffa, F. Z. Lussier, Andréa Lessa Benedet, Nicholas J. Ashton, G. Triana-Baltzer, H. C. Kolb, C. Tissot, J. Therriault, S. Servaes, J. Stevenson, N. Rahmouni, O. L. Lopez, D. L. Tudorascu, V. L. Villemagne, M. D. Ikonomovic, S. Gauthier, E. R. Zimmer, Henrik Zetterberg, Kaj Blennow, H. J. Aizenstein, W. E. Klunk, B. E. Snitz, P. Maki, R. C. Thurston, A. D. Cohen, M. Ganguli, Thomas Karikari, P. Rosa-Neto, T. A. Pascoal
Nature Medicine - 2023 -
Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's
disease.
Shorena Janelidze, Divya Bali, Nicholas J. Ashton, Nicolas R Barthélemy, Jeroen Vanbrabant, Erik Stoops, Eugeen Vanmechelen, Yingxin He, Anna Orduña Dolado, Gallen Triana-Baltzer, Michael J Pontecorvo, Henrik Zetterberg, Hartmuth Kolb, Manu Vandijck, Kaj Blennow, Randall J Bateman, Oskar Hansson
Brain : a journal of neurology - 2023 -
Clinical performance and head-to-head comparison of CSF p-tau235 with p-tau181, p-tau217 and p-tau231 in two memory clinic
cohorts
Juan Lantero Rodriguez, A. Vrillon, A. Fernandez-Lebrero, P. Ortiz-Romero, Anniina Snellman, Laia Montoliu-Gaya, Wagner Scheeren Brum, E. Cognat, J. Dumurgier, A. Puig-Pijoan, I. Navalpotro-Gomez, G. Garcia-Escobar, Thomas Karikari, E. Vanmechelen, Nicholas J. Ashton, Henrik Zetterberg, M. Suarez-Calvet, C. Paquet, Kaj Blennow
Alzheimers Research & Therapy - 2023 -
Hippocampal GFAP-positive astrocyte responses to amyloid and tau
pathologies.
Marco Antônio De Bastiani, Bruna Bellaver, Wagner Scheeren Brum, Debora G Souza, Pamela C L Ferreira, Andreia S Rocha, Guilherme Povala, João Pedro Ferrari-Souza, Andréa Lessa Benedet, Nicholas J. Ashton, Thomas Karikari, Henrik Zetterberg, Kaj Blennow, Pedro Rosa-Neto, Tharick A Pascoal, Eduardo R Zimmer
Brain, behavior, and immunity - 2023 -
Plasma GFAP in presymptomatic and symptomatic familial Alzheimer's disease: a longitudinal cohort
study.
Antoinette O'Connor, Emily Abel, Andréa Lessa Benedet, Teresa Poole, Nicholas J. Ashton, Philip Simon John Weston, Amanda J Heslegrave, Natalie Ryan, Suzie Barker, James M Polke, Kaj Blennow, Henrik Zetterberg, Nick C Fox
Journal of neurology, neurosurgery, and psychiatry - 2023 -
Blood biomarkers and neurodegeneration in individuals exposed to repetitive head
impacts.
Charles Bernick, Guogen Shan, Aaron Ritter, Nicholas J. Ashton, Kaj Blennow, Juan Lantero Rodriguez, Anniina Snellman, Henrik Zetterberg
Alzheimer's research & therapy - 2023 -
Association of Serum Brain-Derived Tau With Clinical Outcome and Longitudinal Change in Patients With Severe Traumatic Brain
Injury.
Fernando Gonzalez-Ortiz, Maciej Dulewicz, Nicholas J. Ashton, Przemyslaw R. Kac, Henrik Zetterberg, Emma Andersson, Yara Yakoub, Jörg Hanrieder, Michael Turton, Peter Harrison, Bengt Nellgård, Thomas Karikari, Kaj Blennow
JAMA network open - 2023 -
Association of Chronic Kidney Disease With Plasma NfL and Other Biomarkers of Neurodegeneration: The H70 Birth Cohort Study in
Gothenburg.
Anna Dittrich, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Anna Zettergren, Joel Simrén, Tobias Skillbäck, Sara Shams, Alejandra Machado, Eric Westman, Michael Schöll, Ingmar Skoog, Silke Kern
Neurology - 2023 -
Association of CSF GAP-43 With the Rate of Cognitive Decline and Progression to Dementia in Amyloid-Positive
Individuals.
Annika Öhrfelt, Andréa Lessa Benedet, Nicholas J. Ashton, Hlin Kvartsberg, Manu Vandijck, Michael W Weiner, John Q Trojanowski, Leslie M Shaw, Henrik Zetterberg, Kaj Blennow
Neurology - 2023 -
Comparison of CSF and plasma NfL and pNfH for Alzheimer’s disease diagnosis: a memory clinic
study
Agathe Vrillon, Nicholas J. Ashton, Thomas Karikari, Karl Götze, Emmanuel Cognat, Julien Dumurgier, Matthieu Lilamand, Henrik Zetterberg, Kaj Blennow, Claire Paquet
Journal of Neurology - 2023 -
Neuropsychiatric Symptoms and Microglial Activation in Patients with Alzheimer
Disease
Cristiano Schaffer Aguzzoli, Pâmela C.L. Ferreira, Guilherme Povala, João Pedro Ferrari-Souza, Bruna Bellaver, Carolina Soares Katz, Hussein Zalzale, Firoza Z. Lussier, Francieli Rohden, Sarah Abbas, Douglas T. Leffa, Marina Scop Medeiros, Joseph Therriault, Andréa Lessa Benedet, Cécile Tissot, Stijn Servaes, Nesrine Rahmouni, Arthur Cassa Macedo, Gleb Bezgin, Min Su Kang, Jenna Stevenson, Vanessa Pallen, Ann Cohen, Oscar L. Lopez, Dana L. Tudorascu, William E. Klunk, Victor L. Villemagne, Jean Paul Soucy, Eduardo R. Zimmer, Lucas P. Schilling, Thomas Karikari, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Serge Gauthier, Victor Valcour, Bruce L. Miller, Pedro Rosa-Neto, Tharick A. Pascoal
JAMA network open - 2023 -
The taxonomy of subjective cognitive decline: proposal and first clinical evidence from the Geneva memory clinic
cohort.
Federica Ribaldi, Rafael Palomo, Daniele Altomare, Max Scheffler, Frederic Assal, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Marc Abramowicz, Valentina Garibotto, Christian Chicherio, Giovanni B Frisoni
Research square - 2023 -
Revealing the combined roles of Aβ and tau in Alzheimer's disease via a pathophysiological activity
decoder.
Lazaro M Sanchez-Rodriguez, Gleb Bezgin, Felix Carbonell, Joseph Therriault, Jaime Fernandez-Arias, Stijn Servaes, Nesrine Rahmouni, Cecile Tissot, Jenna Stevenson, Thomas Karikari, Nicholas J. Ashton, Andréa Lessa Benedet, Henrik Zetterberg, Kaj Blennow, Gallen Triana-Baltzer, Hartmuth C Kolb, Pedro Rosa-Neto, Yasser Iturria-Medina
bioRxiv : the preprint server for biology - 2023 -
Plasma p-tau212: antemortem diagnostic performance and prediction of autopsy verification of Alzheimer's disease
neuropathology.
Przemyslaw R. Kac, Fernándo González-Ortiz, Andreja Emeršič, Maciej Dulewicz, Srinivas Koutarapu, Michael Turton, Yang An, Denis Smirnov, Agnieszka Kulczyńska-Przybik, Vijay Varma, Nicholas J. Ashton, Laia Montoliu-Gaya, Elena Camporesi, Izabela Winkel, Bogusław Paradowski, Abhay Moghekar, Juan C Troncoso, Gunnar Brinkmalm, Susan M Resnick, Barbara Mroczko, Hlin Kvartsberg, Milica Gregorič Kramberger, Jörg Hanrieder, Saša Čučnik, Peter Harrison, Henrik Zetterberg, Piotr Lewczuk, Madhav Thambisetty, Uroš Rot, Douglas Galasko, Kaj Blennow, Thomas Karikari
medRxiv : the preprint server for health sciences - 2023 -
Cross-sectional and longitudinal evaluation of plasma glial fibrillary acidic protein to detect and predict clinical syndromes of Alzheimer's
disease
M. Ally, M. A. Sugarman, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Thomas Karikari, H. J. Aparicio, B. Frank, Y. Tripodis, B. Martin, J. N. Palmisano, E. G. Steinberg, I. Simkin, L. A. Farrer, G. R. Jun, K. W. Turk, A. E. Budson, M. K. O'Connor, R. Au, L. E. Goldstein, N. W. Kowall, R. Killiany, R. A. Stern, T. D. Stein, A. C. McKee, W. Q. Qiu, J. Mez, M. L. Alosco
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring - 2023 -
14-3-3 ζ/δ-reported early synaptic injury in Alzheimer's disease is independently mediated by
sTREM2
M. S. Woo, J. Nilsson, J. Therriault, N. Rahmouni, A. Brinkmalm, Andréa Lessa Benedet, Nicholas J. Ashton, A. C. Macedo, S. Servaes, Y. T. Wang, C. Tissot, J. F. Arias, S. A. Hosseini, M. Chamoun, F. Z. Lussier, Thomas Karikari, J. Stevenson, C. Mayer, J. P. Ferrari-Souza, E. Kobayashi, G. Massarweh, M. A. Friese, T. A. Pascoal, S. Gauthier, Henrik Zetterberg, Kaj Blennow, P. Rosa-Neto
Journal of Neuroinflammation - 2023 -
Elevated plasma sclerostin is associated with high brain amyloid-β load in cognitively normal older
adults
J. Yuan, S. Pedrini, R. Thota, J. Doecke, P. Chatterjee, H. R. Sohrabi, C. E. Teunissen, I. M. W. Verberk, E. Stoops, H. Vanderstichele, B. P. Meloni, C. Mitchell, S. Rainey-Smith, K. Goozee, A. C. P. Tai, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, J. J. Gao, D. L. Liu, F. Mastaglia, C. Inderjeeth, M. H. Zheng, R. N. Martins
Npj Aging - 2023 -
Ultra-high field imaging, plasma markers and autopsy data uncover a specific rostral locus coeruleus vulnerability to hyperphosphorylated
tau
M. Van Egroo, J. M. Riphagen, Nicholas J. Ashton, S. Janelidze, R. A. Sperling, K. A. Johnson, H. S. Yang, D. A. Bennett, Kaj Blennow, O. Hansson, Henrik Zetterberg, H. I. L. Jacobs
Molecular Psychiatry - 2023 -
Equivalence of plasma p-tau217 with cerebrospinal fluid in the diagnosis of Alzheimer's
disease
J. Therriault, S. Servaes, C. Tissot, N. Rahmouni, Nicholas J. Ashton, Andréa Lessa Benedet, Thomas Karikari, A. C. Macedo, F. Z. Lussier, J. Stevenson, Y. T. Wang, J. Fernandez-Arias, A. Stevenson, K. Q. Socualaya, A. Haeger, T. Nazneen, Aumont, Aumont,, A. Hosseini, S. Rej, P. Vitali, G. Triana-Baltzer, H. C. Kolb, J. P. Soucy, T. A. Pascoal, S. Gauthier, Henrik Zetterberg, Kaj Blennow, P. Rosa-Neto
Alzheimers & Dementia - 2023 -
Mass spectrometric simultaneous quantification of tau species in plasma shows differential associations with amyloid and tau
pathologies
Laia Montoliu-Gaya, Andréa Lessa Benedet, C. Tissot, A. Vrillon, Nicholas J. Ashton, Wagner Scheeren Brum, Juan Lantero Rodriguez, J. Stevenson, Johanna Nilsson, Mathias Sauer, N. Rahmouni, Gunnar Brinkmalm, F. Z. Lussier, T. A. Pascoal, Ingmar Skoog, Silke Kern, Henrik Zetterberg, C. Paquet, Johan Gobom, P. Rosa-Neto, Kaj Blennow
Nature Aging - 2023 -
Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma
Biomarkers
N. Mattsson-Carlgren, G. Salvado, Nicholas J. Ashton, P. Tideman, E. Stomrud, Henrik Zetterberg, R. Ossenkoppele, T. J. Betthauser, K. A. Cody, E. M. Jonaitis, R. Langhough, S. Palmqvist, Kaj Blennow, S. Janelidze, S. C. Johnson, O. Hansson
Jama Neurology - 2023 -
Brain atrophy and white matter hyperintensities are independently associated with plasma neurofilament light chain in an Asian cohort of cognitively impaired patients with concomitant cerebral small vessel
disease
J. R. Chong, S. Hilal, Nicholas J. Ashton, Thomas Karikari, A. Reilhac, H. Vrooman, Michael Schöll, Henrik Zetterberg, Kaj Blennow, C. P. Chen, M. K. P. Lai
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring - 2023 -
Plasma and cerebrospinal fluid glial fibrillary acidic protein levels in adults with Down syndrome: a longitudinal cohort
study
Laia Montoliu-Gaya, D. Alcolea, Nicholas J. Ashton, J. Pegueroles, J. Levin, B. Bosch, Juan Lantero Rodriguez, M. Carmona-Iragui, O. Wagemann, M. Balasa, Przemyslaw R. Kac, I. Barroeta, A. Llado, Wagner Scheeren Brum, L. Videla, Fernando Gonzalez-Ortiz, B. Benejam, J. J. A. Martinez, Thomas Karikari, G. Nubling, A. Bejanin, Andréa Lessa Benedet, R. Blesa, A. Lleo, Kaj Blennow, R. Sanchez-Valle, Henrik Zetterberg, J. Fortea
eBioMedicine - 2023 -
Plasma neurofilament light is a predictor of neurological outcome 12 h after cardiac
arrest
H. Levin, A. Lybeck, A. Frigyesi, I. Arctaedius, B. Thorgeirsdottir, M. Annborn, M. Moseby-Knappe, N. Nielsen, T. Cronberg, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, H. Friberg, N. Mattsson-Carlgren
Critical Care - 2023 -
Transient Changes in the Plasma of Astrocytic and Neuronal Injury Biomarkers in COVID-19 Patients without Neurological
Syndromes
M. P. Lennol, Nicholas J. Ashton, O. Moreno-Perez, M. S. Garcia-Ayllon, J. M. Ramos-Rincon, M. Andres, J. M. Leon-Ramirez, V. Boix, J. Gil, Kaj Blennow, E. Merino, Henrik Zetterberg, J. Saez-Valero
International Journal of Molecular Sciences - 2023 -
Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle
loads
G. Salvado, R. Ossenkoppele, Nicholas J. Ashton, T. G. Beach, G. E. Serrano, E. M. Reiman, Henrik Zetterberg, N. Mattsson-Carlgren, S. Janelidze, Kaj Blennow, O. Hansson
Embo Molecular Medicine - 2023 -
Head-to-head comparison of plasma p-tau181, p-tau231 and glial fibrillary acidic protein in clinically unimpaired elderly with three levels of APOE4-related risk for Alzheimer's
disease
Anniina Snellman, L. L. Ekblad, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, E. Pietila, M. Koivumaki, S. Helin, M. Karrasch, Henrik Zetterberg, Kaj Blennow, J. O. Rinne
Neurobiology of Disease - 2023 -
APOEε4 associates with microglial activation independently of Aβ plaques and tau
tangles
J. P. Ferrari-Souza, F. Z. Lussier, D. T. Leffa, J. Therriault, C. Tissot, B. Bellaver, P. C. L. Ferreira, M. Malpetti, Y. T. Wang, G. Povala, Andréa Lessa Benedet, Nicholas J. Ashton, M. Chamoun, S. Servaes, G. Bezgin, M. S. Kang, J. Stevenson, N. Rahmouni, V. Pallen, N. M. Poltronetti, J. T. O'Brlen, J. B. Rowe, A. D. Cohen, O. L. Lopez, D. L. Tudorascu, Thomas Karikari, W. E. Klunk, V. L. Villemagne, J. P. Soucy, S. Gauthier, D. O. Souza, Henrik Zetterberg, Kaj Blennow, E. R. Zimmer, P. Rosa-Neto, T. A. Pascoal
Science Advances - 2023 -
Preanalytical stability of plasma biomarkers for Alzheimer's disease
pathology
A. L. Sunde, I. V. Alsnes, D. Aarsland, Nicholas J. Ashton, D. A. Tovar-Rios, Giovanni de Santis, Kaj Blennow, Henrik Zetterberg, S. R. Kjosavik
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring - 2023 -
Cerebrospinal fluid and positron-emission tomography biomarkers for noradrenergic dysfunction in neurodegenerative diseases: a systematic review and
meta-analysis
E. Lancini, L. Haag, F. Bartl, M. Ruhling, Nicholas J. Ashton, Henrik Zetterberg, E. Duzel, D. Hammerer, M. J. Betts
Brain Communications - 2023 -
APOE epsilon 4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired
elderly
Anniina Snellman, L. L. Ekblad, J. Tuisku, M. Koivumaki, Nicholas J. Ashton, Juan Lantero Rodriguez, Thomas Karikari, S. Helin, M. Bucci, E. Loyttyniemi, R. Parkkola, M. Karrasch, Michael Schöll, Henrik Zetterberg, Kaj Blennow, J. O. Rinne
Alzheimers Research & Therapy - 2023 -
Blood-brain barrier opening of the default mode network in Alzheimer's disease with magnetic resonance-guided focused
ultrasound
Y. Meng, M. Goubran, J. S. Rabin, M. McSweeney, J. Ottoy, C. B. Pople, Y. X. Huang, A. Storace, M. Ozzoude, A. Bethune, B. Lam, W. Swardfager, C. Heyn, A. Abrahao, B. Davidson, C. Hamani, I. Aubert, Henrik Zetterberg, Nicholas J. Ashton, Thomas Karikari, Kaj Blennow, S. E. Black, K. Hynynen, N. Lipsman
Brain - 2023 -
Astrocyte biomarker signatures of amyloid-beta and tau pathologies in Alzheimer's
disease
J. P. Ferrari-Souza, P. C. L. Ferreira, B. Bellaver, C. Tissot, Y. T. Wang, D. T. Leffa, Wagner Scheeren Brum, Andréa Lessa Benedet, Nicholas J. Ashton, M. A. De Bastiani, A. Rocha, J. Therriault, F. Z. Lussier, M. Chamoun, S. Servaes, G. Bezgin, M. S. Kang, J. Stevenson, N. Rahmouni, V. Pallen, N. M. Poltronetti, W. E. Klunk, D. L. Tudorascu, A. D. Cohen, V. L. Villemagne, S. Gauthier, Kaj Blennow, Henrik Zetterberg, D. O. Souza, Thomas Karikari, E. R. Zimmer, P. Rosa-Neto, T. A. Pascoal
Molecular Psychiatry - 2022 -
Is amyloid involved in acute neuroinflammation? A CSF analysis in
encephalitis
A. Padovani, A. Canale, L. Schiavon, S. Masciocchi, A. Imarisio, B. Risi, G. Bonzi, V. De Giuli, M. Di Luca, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, A. Pilotto
Alzheimers & Dementia - 2022 -
Plasma and CSF NfL are differentially associated with biomarker evidence of neurodegeneration in a community-based sample of
70-year-olds
Anna Dittrich, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Joel Simrén, Fiona Geiger, Anna Zettergren, S. Shams, A. Machado, E. Westman, Michael Schöll, Ingmar Skoog, Silke Kern
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring - 2022 -
Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's
disease
Nicholas J. Ashton, Andréa Lessa Benedet, Tharick A. Pascoal, Thomas Karikari, Juan Lantero Rodriguez, Wagner Scheeren Brum, S. Mathotaarachchi, J. Therriault, M. Savard, M. Chamoun, E. Stoops, C. Francois, E. Vanmechelen, S. Gauthier, E. R. Zimmer, Henrik Zetterberg, Kaj Blennow, P. Rosa-Neto
Ebiomedicine - 2022 -
Association of Plasma p-tau181 and p-tau231 Concentrations With Cognitive Decline in Patients With Probable Dementia With Lewy
Bodies.
Maria C Gonzalez, Nicholas J. Ashton, Bárbara Fernandes Gomes, Diego Alejandro Tovar-Rios, Frédéric Blanc, Thomas Karikari, Brit Mollenhauer, Andrea Pilotto, Afina Lemstra, Claire Paquet, Carla Abdelnour, Milica G Kramberger, Laura Bonanni, Rik Vandenberghe, Abdul Hye, Kaj Blennow, Henrik Zetterberg, Dag Aarsland
JAMA neurology - 2022 -
Brain Injury Biomarkers for Predicting Outcome After Cardiac
Arrest
J. Humaloja, Nicholas J. Ashton, M. B. Skrifvars
Critical Care - 2022 -
Quantification of SNAP-25 with mass spectrometry and Simoa: a method comparison in Alzheimer's
disease
Johanna Nilsson, Nicholas J. Ashton, Andréa Lessa Benedet, Laia Montoliu-Gaya, Johan Gobom, T. A. Pascoal, M. Chamoun, E. Portelius, A. Jeromin, M. Mendes, Henrik Zetterberg, P. Rosa-Neto, Ann Brinkmalm, Kaj Blennow
Alzheimer's Research & Therapy - 2022 -
Association of Plasma Biomarker Levels With Their CSF Concentration and the Number and Severity of Concussions in Professional
Athletes
Pashtun Shahim, Henrik Zetterberg, Joel Simrén, Nicholas J. Ashton, G. Norato, Michael Schöll, Y. Tegner, R. Diaz-Arrastia, Kaj Blennow
Neurology - 2022 -
Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total
tau.
Brandon Frank, Madeline Ally, Bailee Brekke, Henrik Zetterberg, Kaj Blennow, Michael A Sugarman, Nicholas J. Ashton, Thomas Karikari, Yorghos Tripodis, Brett Martin, Joseph N Palmisano, Eric G Steinberg, Irene Simkina, Katherine W Turk, Andrew E Budson, Maureen K O'Connor, Rhoda Au, Lee E Goldstein, Gyungah R Jun, Neil W Kowall, Thor D Stein, Ann C McKee, Ronald Killiany, Wei Qiao Qiu, Robert A Stern, Jesse Mez, Michael L Alosco
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2022 -
CSF tau368/total-tau ratio reflects cognitive performance and neocortical tau better compared to p-tau181 and p-tau217 in cognitively impaired
individuals.
Joel Simrén, Wagner Scheeren Brum, Nicholas J. Ashton, Andréa Lessa Benedet, Thomas Karikari, Hlin Kvartsberg, Emma Sjons, Firoza Z Lussier, Mira Chamoun, Jenna Stevenson, Robert Hopewell, Vanessa Pallen, Keqiang Ye, Tharick A Pascoal, Henrik Zetterberg, Pedro Rosa-Neto, Kaj Blennow
Alzheimer's research & therapy - 2022 -
Differences between blood and cerebrospinal fluid glial fibrillary Acidic protein levels: The effect of sample
stability
Joel Simrén, Haley Weninger, Wagner Scheeren Brum, Shilla Khalil, Andréa Lessa Benedet, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton
Alzheimers & Dementia - 2022 -
Detecting amyloid positivity in early Alzheimer's disease using combinations of plasma A beta 42/A beta 40 and
p-tau
S. Janelidze, S. Palmqvist, A. Leuzy, E. Stomrud, I. M. W. Verberk, Henrik Zetterberg, Nicholas J. Ashton, P. Pesini, L. Sarasa, J. A. Allue, C. E. Teunissen, J. L. Dage, Kaj Blennow, N. Mattsson-Carlgren, O. Hansson
Alzheimers & Dementia - 2022 -
Validation of the LUMIPULSE automated immunoassay for the measurement of core AD biomarkers in cerebrospinal
fluid.
Johan Gobom, Lucilla Parnetti, Pedro Rosa-Neto, Martin Vyhnalek, Serge Gauthier, Samuela Cataldi, Ondrej Lerch, Jan Laczo, Katerina Cechova, Marcus Clarin, Andrea I Benet, Tharick A Pascoal, Neserine Rahmouni, Manu Vandijck, Else Huyck, Nathalie Le Bastard, Jenna Stevenson, Mira Chamoun, Daniel Alcolea, Alberto Lleó, Ulf Andreasson, Marcel M Verbeek, Giovanni Bellomo, Roberta Rinaldi, Nicholas J. Ashton, Henrik Zetterberg, Katerina Sheardova, Jakub Hort, Kaj Blennow
Clinical chemistry and laboratory medicine - 2022 -
Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer's trial selection and disease
monitoring.
Nicholas J. Ashton, Shorena Janelidze, Niklas Mattsson-Carlgren, Alexa Pichet Binette, Olof Strandberg, Wagner Scheeren Brum, Thomas Karikari, Fernándo González-Ortiz, Guglielmo Di Molfetta, Francisco J Meda, Erin M Jonaitis, Rebecca Langhough Koscik, Karly Cody, Tobey J Betthauser, Yan Li, Eugeen Vanmechelen, Sebastian Palmqvist, Erik Stomrud, Randall J Bateman, Henrik Zetterberg, Sterling C Johnson, Kaj Blennow, Oskar Hansson
Nature medicine - 2022 -
A three-range approach enhances the prognostic utility of CSF biomarkers in Alzheimer's
disease.
Wagner Scheeren Brum, Marco Antônio de Bastiani, Andrei Bieger, Joseph Therriault, João P Ferrari-Souza, Andréa Lessa Benedet, Paramita Saha-Chaudhuri, Diogo O Souza, Nicholas J. Ashton, Henrik Zetterberg, Tharick A Pascoal, Thomas Karikari, Kaj Blennow, Pedro Rosa-Neto, Eduardo R Zimmer
Alzheimer's & dementia (New York, N. Y.) - 2022 -
Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type
neurodegeneration.
Fernando Gonzalez-Ortiz, Michael Turton, Przemyslaw R. Kac, Denis Smirnov, Enrico Premi, Roberta Ghidoni, Luisa Benussi, Valentina Cantoni, Claudia Saraceno, Jasmine Rivolta, Nicholas J. Ashton, Barbara Borroni, Douglas Galasko, Peter Harrison, Henrik Zetterberg, Kaj Blennow, Thomas Karikari
Brain : a journal of neurology - 2022 -
Association of Phosphorylated Tau Biomarkers With Amyloid Positron Emission Tomography vs Tau Positron Emission
Tomography.
Joseph Therriault, Marie Vermeiren, Stijn Servaes, Cécile Tissot, Nicholas J. Ashton, Andréa Lessa Benedet, Thomas Karikari, Juan Lantero Rodriguez, Wagner Scheeren Brum, Firoza Z Lussier, Gleb Bezgin, Jenna Stevenson, Nesrine Rahmouni, Peter Kunach, Yi-Ting Wang, Jaime Fernandez-Arias, Kely Quispialaya Socualaya, Arthur C Macedo, João Pedro Ferrari-Souza, Pâmela C L Ferreira, Bruna Bellaver, Douglas T Leffa, Eduardo R Zimmer, Paolo Vitali, Jean-Paul Soucy, Gallen Triana-Baltzer, Hartmuth C Kolb, Tharick A Pascoal, Paramita Saha-Chaudhuri, Serge Gauthier, Henrik Zetterberg, Kaj Blennow, Pedro Rosa-Neto
JAMA neurology - 2022 -
Biomarker modeling of Alzheimer’s disease using PET-based Braak
staging
J. Therriault, T. A. Pascoal, F. Z. Lussier, C. Tissot, M. Chamoun, G. Bezgin, S. Servaes, Andréa Lessa Benedet, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, P. Kunach, Y. T. Wang, J. Fernandez-Arias, G. Massarweh, P. Vitali, J. P. Soucy, P. Saha-Chaudhuri, Kaj Blennow, Henrik Zetterberg, S. Gauthier, P. Rosa-Neto
Nature Aging - 2022 -
Antibody-free measurement of cerebrospinal fluid tau phosphorylation across the Alzheimer's disease
continuum.
Johan Gobom, Andréa Lessa Benedet, Niklas Mattsson-Carlgren, Laia Montoliu-Gaya, Nina Schultz, Nicholas J. Ashton, Shorena Janelidze, Stijn Servaes, Mathias Sauer, Tharick A Pascoal, Thomas Karikari, Juan Lantero Rodriguez, Gunnar Brinkmalm, Henrik Zetterberg, Oskar Hansson, Pedro Rosa-Neto, Kaj Blennow
Molecular neurodegeneration - 2022 -
The extent of neuroradiological findings in COVID-19 shows correlation with blood biomarkers, Glasgow coma scale score and days in intensive
care.
David Fällmar, Elham Rostami, Eva Kumlien, Nicholas J. Ashton, Sven Jackmann, Radu Pavel, Kaj Blennow, Michael Hultström, Miklos Lipcsey, Robert Frithiof, Gabriel Westman, Henrik Zetterberg, Johan Wikström, Johan Virhammar
Journal of neuroradiology = Journal de neuroradiologie - 2022 -
N-terminal and mid-region tau fragments as fluid biomarkers in neurological
diseases.
Anniina Snellman, Juan Lantero Rodriguez, Andreja Emeršič, Agathe Vrillon, Thomas Karikari, Nicholas J. Ashton, Milica Gregorič Kramberger, Saša Čučnik, Claire Paquet, Uroš Rot, Henrik Zetterberg, Kaj Blennow
Brain : a journal of neurology - 2022 -
Editorial: Blood Biomarkers of Neurodegenerative
Diseases.
Thomas Karikari, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow
Frontiers in molecular neuroscience - 2022 -
Differences Between Plasma and Cerebrospinal Fluid p-tau181 and p-tau231 in Early Alzheimer's
Disease.
Andrea Pilotto, Marta Parigi, Giulio Bonzi, Beatrice Battaglio, Elisabetta Ferrari, Lorenza Mensi, Alberto Benussi, Salvatore Caratozzolo, Maura Cosseddu, Rosanna Turrone, Silvana Archetti, Nicholas J. Ashton, Henrik Zetterberg, Silvia Giliani, Alessandro Padovani
Journal of Alzheimer's disease : JAD - 2022 -
Amyloid processing in COVID-19-associated neurological
syndromes
O. J. Ziff, Nicholas J. Ashton, P. R. Mehta, R. Brown, D. Athauda, J. Heaney, A. J. Heslegrave, Andréa Lessa Benedet, Kaj Blennow, A. M. Checkley, C. F. Houlihan, S. Gauthier, P. Rosa-Neto, N. C. Fox, J. M. Schott, Henrik Zetterberg, L. A. Benjamin, R. W. Paterson
Journal of Neurochemistry - 2022 -
CSF biomarkers and plasma p-tau181 as predictors of longitudinal tau accumulation: Implications for clinical trial
design
Alexis Moscoso Rial, Thomas Karikari, Michel J. Grothe, Nicholas J. Ashton, Juan Lantero Rodriguez, Anniina Snellman, Henrik Zetterberg, Kaj Blennow, Michael Schöll
Alzheimer's and Dementia - 2022 -
Plasma p-tau231, p-tau181, PET Biomarkers, and Cognitive Change in Older
Adults.
Pierre-François Meyer, Nicholas J. Ashton, Thomas Karikari, Cherie Strikwerda-Brown, Theresa Köbe, Julie Gonneaud, Alexa Pichet Binette, Hazal Ozlen, Yara Yakoub, Joel Simrén, Josef Pannee, Juan Lantero Rodriguez, Anne Labonté, Suzanne L Baker, Michael Schöll, Eugeen Vanmechelen, John C S Breitner, Henrik Zetterberg, Kaj Blennow, Judes Poirier, Sylvia Villeneuve
Annals of neurology - 2022 -
Differences and similarities between familial and sporadic frontotemporal dementia: An Italian single-center cohort
study
A. Benussi, I. Libri, E. Premi, A. Alberici, V. Cantoni, Y. Gadola, J. Rivolta, M. Pengo, S. Gazzina, V. D. Calhoun, R. Gasparotti, Henrik Zetterberg, Nicholas J. Ashton, Kaj Blennow, A. Padovani, B. Borroni
Alzheimer's and Dementia: Translational Research and Clinical Interventions - 2022 -
Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune
responses
E. J. Needham, A. L. Ren, R. J. Digby, E. J. Norton, S. Ebrahimi, J. G. Outtrim, D. A. Chatfield, A. E. Manktelow, M. M. Leibowitz, V. F. J. Newcombe, R. Doffinger, G. Barcenas-Morales, C. Fonseca, M. J. Taussig, R. M. Burnstein, R. J. Samanta, C. Dunai, N. Sithole, Nicholas J. Ashton, Henrik Zetterberg, Magnus Gisslén, Arvid Edén, Emelie Marklund, P. J. M. Openshaw, J. Dunning, M. J. Griffiths, J. Cavanagh, G. Breen, S. R. Irani, A. Elmer, N. Kingston, C. Summers, J. R. Bradley, L. S. Taams, B. D. Michael, E. T. Bullmore, K. G. C. Smith, P. A. Lyons, A. J. Coles, D. K. Menon
Brain - 2022 -
Acute sleep loss increases CNS health biomarkers and compromises the ability to stay awake in a sex-and weight-specific
manner
L. T. van Egmond, S. Bukhari, Andréa Lessa Benedet, Nicholas J. Ashton, E. M. S. Meth, A. Boukas, J. Engstrom, M. Ilemosoglou, Kaj Blennow, Henrik Zetterberg, C. Benedict
Translational Psychiatry - 2022 -
Alzheimer's Disease Plasma Biomarkers Distinguish Clinical Diagnostic Groups in Memory Clinic
Patients
M. Gerards, A. K. Schild, D. Meiberth, A. Rostamzadeh, J. J. Vehreschild, S. Wingen-Heimann, W. Johannis, P. M. Adami, O. A. Onur, A. Ramirez, Thomas Karikari, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, F. Maier, F. Jessen
Dementia and Geriatric Cognitive Disorders - 2022 -
Diagnostic value of serum versus plasma phospho-tau for Alzheimer's
disease
Przemyslaw R. Kac, Fernando Gonzalez-Ortiz, Joel Simrén, N. Dewit, E. Vanmechelen, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Thomas Karikari
Alzheimer's Research & Therapy - 2022 -
Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical
utility
Thomas Karikari, Nicholas J. Ashton, Gunnar Brinkmalm, Wagner Scheeren Brum, Andréa Lessa Benedet, Laia Montoliu-Gaya, Juan Lantero Rodriguez, T. A. Pascoal, M. Suarez-Calvet, P. Rosa-Neto, Kaj Blennow, Henrik Zetterberg
Nature Reviews Neurology - 2022 -
Post-acute blood biomarkers and disease progression in traumatic brain
injury.
Virginia F J Newcombe, Nicholas J. Ashton, Jussi P Posti, Ben Glocker, Anne Manktelow, Doris A Chatfield, Stefan Winzeck, Edward Needham, Marta M Correia, Guy B Williams, Joel Simrén, Riikka S K Takala, Ari J Katila, Henna-Riikka Maanpää, Jussi Tallus, Janek Frantzén, Kaj Blennow, Olli Tenovuo, Henrik Zetterberg, David K Menon
Brain : a journal of neurology - 2022 -
The accuracy and robustness of plasma biomarker models for amyloid PET
positivity
Andréa Lessa Benedet, Wagner Scheeren Brum, O. Hansson, A. D. N. Initiative, Thomas Karikari, E. R. Zimmer, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton
Alzheimers Research & Therapy - 2022 -
Plasma biomarkers for Alzheimer's Disease in relation to neuropathology and cognitive
change
D. S. Smirnov, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Joel Simrén, Juan Lantero Rodriguez, Thomas Karikari, A. Hiniker, R. A. Rissman, D. P. Salmon, D. Galasko
Acta Neuropathologica - 2022 -
Apolipoprotein B is a novel marker for early tau pathology in Alzheimer's
disease
C. Picard, N. Nilsson, A. Labonte, D. Auld, P. Rosa-Neto, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, J. C. B. Breitner, S. Villeneuve, J. Poirier
Alzheimers & Dementia - 2022 -
Effect of Race on Prediction of Brain Amyloidosis by Plasma Aβ42/Aβ40, Phosphorylated Tau, and Neurofilament
Light.
Suzanne E Schindler, Thomas Karikari, Nicholas J. Ashton, Rachel L Henson, Kevin E Yarasheski, Tim West, Mathew R Meyer, Kristopher M Kirmess, Yan Li, Benjamin Saef, Krista L Moulder, David Bradford, Anne M Fagan, Brian A Gordon, Tammie L S Benzinger, Joyce Balls-Berry, Randall J Bateman, Chengjie Xiong, Henrik Zetterberg, Kaj Blennow, John C Morris
Neurology - 2022 -
Publisher Correction: Plasma p-tau231 and p-tau217 as state markers of amyloid-β pathology in preclinical Alzheimer's
disease.
Marta Milà-Alomà, Nicholas J. Ashton, Mahnaz Shekari, Gemma Salvadó, Paula Ortiz-Romero, Laia Montoliu-Gaya, Andréa Lessa Benedet, Thomas Karikari, Juan Lantero Rodriguez, Eugeen Vanmechelen, Theresa A Day, Armand González-Escalante, Gonzalo Sánchez-Benavides, Carolina Minguillon, Karine Fauria, José Luis Molinuevo, Jeffrey L Dage, Henrik Zetterberg, Juan Domingo Gispert, Marc Suárez-Calvet, Kaj Blennow
Nature medicine - 2022 -
Diagnostic and prognostic plasma biomarkers for preclinical Alzheimer's
disease.
Pratishtha Chatterjee, Steve Pedrini, Nicholas J. Ashton, Michelle Tegg, Kathryn Goozee, Abhay K Singh, Thomas Karikari, Joel Simrén, Eugeen Vanmechelen, Nicola J Armstrong, Eugene Hone, Prita R Asih, Kevin Taddei, Vincent Doré, Victor L Villemagne, Hamid R Sohrabi, Henrik Zetterberg, Colin L Masters, Kaj Blennow, Ralph N Martins
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2022 -
Reactive astrogliosis is associated with higher cerebral glucose consumption in the early Alzheimer's
continuum
G. Salvado, M. Mila-Aloma, M. Shekari, Nicholas J. Ashton, G. Operto, C. Falcon, R. Cacciaglia, C. Minguillon, K. Fauria, A. Ninerola-Baizan, A. Perissinotti, Andréa Lessa Benedet, G. Kollmorgen, I. Suridjan, N. Wild, J. L. Molinuevo, Henrik Zetterberg, Kaj Blennow, M. Suarez-Calvet, J. D. Gispert
European Journal of Nuclear Medicine and Molecular Imaging - 2022 -
Evaluation of in vivo staging of amyloid deposition in cognitively unimpaired elderly aged
78-94
M. M. Michalowska, K. Herholz, R. Hinz, C. Amadi, L. McInnes, J. M. Anton-Rodriguez, Thomas Karikari, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, N. Pendleton, S. F. Carter
Molecular Psychiatry - 2022 -
Classification accuracy of blood-based and neurophysiological markers in the differential diagnosis of Alzheimer's disease and frontotemporal lobar
degeneration
A. Benussi, V. Cantoni, J. Rivolta, S. Archetti, A. Micheli, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, B. Borroni
Alzheimers Research & Therapy - 2022 -
Sex influences clinical phenotype in frontotemporal
dementia
M. Pengo, A. Alberici, I. Libri, A. Benussi, Y. Gadola, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, B. Borroni
Neurological Sciences - 2022 -
Ante-mortem plasma phosphorylated tau (181) predicts Alzheimer's disease neuropathology and regional tau at
autopsy
M. S. Morrison, H. J. Aparicio, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Thomas Karikari, Y. Tripodis, B. Martin, J. N. Palmisano, M. A. Sugarman, B. Frank, E. G. Steinberg, K. W. Turk, A. E. Budson, R. Au, L. E. Goldstein, G. R. Jun, N. W. Kowall, R. Killiany, W. Q. Qiu, R. A. Stern, J. Mez, A. C. McKee, T. D. Stein, M. L. Alosco
Brain - 2022 -
Plasma p-tau231 and p-tau217 as state markers of amyloid-beta pathology in preclinical Alzheimer's
disease
M. Mila-Aloma, Nicholas J. Ashton, M. Shekari, G. Salvado, P. Ortiz-Romero, Laia Montoliu-Gaya, Andréa Lessa Benedet, Thomas Karikari, Juan Lantero Rodriguez, E. Vanmechelen, T. A. Day, A. Gonzalez-Escalante, G. Sanchez-Benavides, C. Minguillon, K. Fauria, J. L. Molinuevo, J. L. Dage, Henrik Zetterberg, J. D. Gispert, M. Suarez-Calvet, Kaj Blennow
Nature Medicine - 2022 -
Decreased Electroencephalography Global Field Synchronization in Slow-Frequency Bands Characterizes Synaptic Dysfunction in Amnestic Subtypes of Mild Cognitive
Impairment.
Una Smailovic, Daniel Ferreira, Birgitta Ausén, Nicholas J. Ashton, Thomas Koenig, Henrik Zetterberg, Kaj Blennow, Vesna Jelic
Frontiers in aging neuroscience - 2022 -
GFAp and tau protein as predictors of neurological outcome after out-of-hospital cardiac arrest: A post hoc analysis of the COMACARE
trial
J. Humaloja, M. Lähde, Nicholas J. Ashton, R. Matti, J. Hästbacka, P. Jakkula, H. Friberg, T. Cronberg, V. Pettilä, Kaj Blennow, Henrik Zetterberg, M. B. Skrifvars
Resuscitation - 2022 -
Plasma pTau181 predicts cortical brain atrophy in aging and Alzheimer's
disease.
Cécile Tissot, Andréa Lessa Benedet, Joseph Therriault, Tharick A Pascoal, Firoza Z Lussier, Paramita Saha-Chaudhuri, Mira Chamoun, Melissa Savard, Sulantha S Mathotaarachchi, Gleb Bezgin, Yi-Ting Wang, Jaime Fernandez Arias, Juan Rodriguez, Anniina Snellman, Nicholas J. Ashton, Thomas Karikari, Kaj Blennow, Henrik Zetterberg, Etienne De Villers-Sidani, Philippe Huot, Serge Gauthier, Pedro Rosa-Neto
Alzheimer's Research & Therapy - 2021 -
Associations of Fully Automated CSF and Novel Plasma Biomarkers With Alzheimer Disease Neuropathology at
Autopsy.
Michel J. Grothe, Alexis Moscoso Rial, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, Anniina Snellman, Henrik Zetterberg, Kaj Blennow, Michael Schöll
Neurology - 2021 -
Population-based blood screening for preclinical Alzheimer's disease in a British birth cohort at age
70.
Ashvini Keshavan, Josef Pannee, Thomas Karikari, Juan Rodriguez, Nicholas J. Ashton, Jennifer M Nicholas, David M Cash, William Coath, Christopher A Lane, Thomas D Parker, Kirsty Lu, Sarah M Buchanan, Sarah E Keuss, Sarah-Naomi James, Heidi Murray-Smith, Andrew Wong, Anna Barnes, John C Dickson, Amanda Heslegrave, Erik Portelius, Marcus Richards, Nick C Fox, Henrik Zetterberg, Kaj Blennow, Jonathan M Schott
Brain : a journal of neurology - 2021 -
Synaptic Molecular and Neurophysiological Markers Are Independent Predictors of Progression in Alzheimer's
Disease
U. Smailovic, I. Kareholt, T. Koenig, Nicholas J. Ashton, B. Winblad, K. Hoglund, P. Nilsson, Henrik Zetterberg, Kaj Blennow, V. Jelic
Journal of Alzheimers Disease - 2021 -
Blood neurofilament light in remote settings: Alternative protocols to support sample collection in challenging pre-analytical
conditions.
Joel Simrén, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg
Alzheimer's & dementia - 2021 -
Head-to-head comparison of clinical performance of CSF phospho-tau T181 and T217 biomarkers for Alzheimer's disease
diagnosis.
Thomas Karikari, Agathe Vrillon, Juan Lantero Rodriguez, Nicholas J. Ashton, Milica Gregorič Kramberger, Julien Dumurgier, Claire Hourregue, Saša Čučnik, Gunnar Brinkmalm, Uroš Rot, Henrik Zetterberg, Claire Paquet, Kaj Blennow
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2021 -
Complex Autoantibody Responses Occur following Moderate to Severe Traumatic Brain
Injury.
Edward J Needham, Oda Stoevesandt, Eric P Thelin, Henrik Zetterberg, Elisa R Zanier, Faiez Al Nimer, Nicholas J. Ashton, Joanne G Outtrim, Virginia F J Newcombe, Hani S Mousa, Joel Simrén, Kaj Blennow, Zhihui Yang, Peter J Hutchinson, Fredrik Piehl, Adel E Helmy, Mike J Taussig, Kevin K W Wang, Joanne L Jones, David K Menon, Alasdair J Coles
Journal of immunology - 2021 -
Serum and cerebrospinal fluid biomarker profiles in acute SARS-CoV-2-associated neurological
syndromes.
Ross W Paterson, Laura A Benjamin, Puja R Mehta, Rachel L Brown, Dilan Athauda, Nicholas J. Ashton, Claire A Leckey, Oliver J Ziff, Judith Heaney, Amanda J Heslegrave, Andréa Lessa Benedet, Kaj Blennow, Anna M Checkley, Catherine F Houlihan, Catherine J Mummery, Michael P Lunn, Hadi Manji, Michael S Zandi, Stephen Keddie, Michael Chou, Deepthi Vinayan Changaradil, Tom Solomon, Ashvini Keshavan, Suzanne Barker, Hans Rolf Jäger, Francesco Carletti, Robert Simister, David J Werring, Moira J Spyer, Eleni Nastouli, Serge Gauthier, Pedro Rosa-Neto, Henrik Zetterberg, Jonathan M Schott
Brain communications - 2021 -
A genome-wide association study of plasma phosphorylated
tau181
Jodie Lord, Anna Zettergren, Nicholas J. Ashton, Thomas Karikari, Andréa Lessa Benedet, Joel Simrén, Abdul Hye, Dag Aarsland, Kaj Blennow, Henrik Zetterberg, Petroula Proitsi
Neurobiology of aging - 2021 -
Ultra-Early Differential Diagnosis of Acute Cerebral Ischemia and Hemorrhagic Stroke by Measuring the Prehospital Release Rate of
GFAP
O. S. Mattila, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, H. Harve-Rytsala, S. Pihlasviita, J. Ritvonen, G. Sibolt, T. Nukarinen, S. Curtze, D. Strbian, M. Pystynen, Turgut Tatlisumak, M. Kuisma, P. J. Lindsberg
Clinical Chemistry - 2021 -
Association of plasma P-tau181 with memory decline in non-demented
adults
J. Therriault, A. L. Benedet, T. A. Pascoal, F. Z. Lussier, C. Tissot, Thomas Karikari, Nicholas J. Ashton, M. Chamoun, G. Bezgin, S. Mathotaarachchi, S. Gauthier, P. Saha-Chaudhuri, Henrik Zetterberg, Kaj Blennow, P. Rosa-Neto
Brain Communications - 2021 -
Plasma Neurofilament Light Chain Predicts Cognitive Progression in Prodromal and Clinical Dementia with Lewy
Bodies
A. Pilotto, A. Imarisio, C. Carrarini, M. Russo, S. Masciocchi, S. Gipponi, E. Cottini, D. Aarsland, Henrik Zetterberg, Nicholas J. Ashton, A. Hye, L. Bonanni, A. Padovani
Journal of Alzheimers Disease - 2021 -
Plasma sTREM2: a potential marker of cerebrovascular injury in neurodegenerative
disorders
E. Rodriguez-Vieitez, Nicholas J. Ashton
Brain - 2021 -
Changes in Blood Biomarkers of Brain Injury and Degeneration Following Long-Duration
Spaceflight.
Peter Zu Eulenburg, Judith-Irina Buchheim, Nicholas J. Ashton, Galina Vassilieva, Kaj Blennow, Henrik Zetterberg, Alexander Choukér
JAMA neurology - 2021 -
The reliability and validity of DSM 5 diagnostic criteria for neurocognitive disorder and relationship with plasma neurofilament light in a down syndrome
population
S. E. Pape, T. Al Janabi, Nicholas J. Ashton, A. Hye, R. Sheehan, P. Gallagher, B. Knight, A. M. Prins, K. Courtenay, V. Jordanova, B. Thomas, N. Perumal, C. Forbes, A. Hassiotis, A. Strydom
Scientific Reports - 2021 -
Transitioning from cerebrospinal fluid to blood tests to facilitate diagnosis and disease monitoring in Alzheimer's
disease.
Deborah O T Alawode, Amanda J Heslegrave, Nicholas J. Ashton, Thomas Karikari, Joel Simrén, Laia Montoliu-Gaya, Josef Pannee, Antoinette O Connor, Philip S J Weston, Juan Lantero Rodriguez, Ashvini Keshavan, Anniina Snellman, Johan Gobom, Ross W Paterson, Jonathan M Schott, Kaj Blennow, Nick C Fox, Henrik Zetterberg
Journal of internal medicine - 2021 -
The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's
disease.
Joel Simrén, Antoine Leuzy, Thomas Karikari, Abdul Hye, Andréa Lessa Benedet, Juan Lantero Rodriguez, Niklas Mattsson-Carlgren, Michael Schöll, Patrizia Mecocci, Bruno Vellas, Magda Tsolaki, Iwona Kloszewska, Hilkka Soininen, Simon Lovestone, Dag Aarsland, Oskar Hansson, Pedro Rosa-Neto, Eric Westman, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2021 -
Plasma P-tau181 to Aβ42 ratio is associated with brain amyloid burden and hippocampal atrophy in an Asian cohort of Alzheimer's disease patients with concomitant cerebrovascular
disease.
Joyce R Chong, Nicholas J. Ashton, Thomas Karikari, Tomotaka Tanaka, Francis N Saridin, Anthonin Reilhac, Edward G Robins, Ying-Hwey Nai, Henri Vrooman, Saima Hilal, Henrik Zetterberg, Kaj Blennow, Mitchell K P Lai, Christopher P Chen
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2021 -
Head-to-head comparison of amplified plasmonic exosome Aβ42 platform and single-molecule array immunoassay in a memory clinic
cohort.
Tomotaka Tanaka, Joyce Chong Ruifen, Ying-Hwey Nai, Chin Hong Tan, Carine Z J Lim, Yan Zhang, Mary C Stephenson, Saima Hilal, Francis N Saridin, Bibek Gyanwali, Steven Villaraza, Edward G Robins, Masafumi Ihara, Michael Schöll, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Huilin Shao, Anthonin Reilhac, Christopher Chen
European journal of neurology - 2021 -
Plasma Cystatin C correlates with plasma NfL levels and predicts disease progression in Parkinson's
disease.
Alberto Imarisio, Andrea Pilotto, Emirena Garrafa, Francesca Conforti, Stefano Masciocchi, Rosanna Turrone, Stefano Gipponi, Elisabetta Cottini, Maria Cristina Rizzetti, Vanessa Porrini, Cristina Gussago, Marina Pizzi, Fiorella Guadagni, Henrik Zetterberg, Nicholas J. Ashton, Abdul Hye, Alessandro Padovani
Neuro-degenerative diseases - 2021 -
Clinical and analytical comparison of six Simoa assays for plasma P-tau isoforms P-tau181, P-tau217, and
P-tau231.
Sherif Bayoumy, Inge M W Verberk, Ben den Dulk, Zulaiga Hussainali, Marissa Zwan, Wiesje M van der Flier, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Jeroen Vanbrabant, Erik Stoops, Eugeen Vanmechelen, Jeffrey L Dage, Charlotte E Teunissen
Alzheimer's research & therapy - 2021 -
Prodromal frontotemporal dementia: clinical features and predictors of
progression.
Alberto Benussi, Nicholas J. Ashton, Thomas Karikari, Antonella Alberici, Claudia Saraceno, Roberta Ghidoni, Luisa Benussi, Henrik Zetterberg, Kaj Blennow, Barbara Borroni
Alzheimer's research & therapy - 2021 -
P-tau235: a novel biomarker for staging preclinical Alzheimer's
disease.
Juan Lantero Rodriguez, Anniina Snellman, Andréa Lessa Benedet, Marta Milà-Alomà, Elena Camporesi, Laia Montoliu-Gaya, Nicholas J. Ashton, Agathe Vrillon, Thomas Karikari, Juan Domingo Gispert, Gemma Salvadó, Mahnaz Shekari, Christina E Toomey, Tammaryn L Lashley, Henrik Zetterberg, Marc Suárez-Calvet, Gunnar Brinkmalm, Pedro Rosa Neto, Kaj Blennow
EMBO molecular medicine - 2021 -
Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease
Continuum
Andréa Lessa Benedet, M. Mila-Aloma, A. Vrillon, Nicholas J. Ashton, T. A. Pascoal, F. Lussier, Thomas Karikari, C. Hourregue, E. Cognat, J. Dumurgier, J. Stevenson, N. Rahmouni, V. Pallen, N. M. Poltronetti, G. Salvado, M. Shekari, G. Operto, J. D. Gispert, C. Minguillon, K. Fauria, G. Kollmorgen, I. Suridjan, E. R. Zimmer, Henrik Zetterberg, J. L. Molinuevo, C. Paquet, P. Rosa-Neto, Kaj Blennow, M. Suarez-Calvet
Jama Neurology - 2021 -
Phosphorylated tau181 in plasma as a potential biomarker for Alzheimer's disease in adults with Down
syndrome
A. Lleo, Henrik Zetterberg, J. Pegueroles, Thomas Karikari, M. Carmona-Iragui, Nicholas J. Ashton, V. Montal, I. Barroeta, Juan Lantero Rodriguez, L. Videla, M. Altuna, B. Benejam, S. Fernandez, S. Valldeneu, D. Garzon, A. Bejanin, M. F. Iulita, V. Camacho, S. Medrano-Martorell, O. Belbin, J. Clarimon, S. Lehmann, D. Alcolea, R. Blesa, Kaj Blennow, J. Fortea
Nature Communications - 2021 -
Plasma levels of phosphorylated tau 181 are associated with cerebral metabolic dysfunction in cognitively impaired and amyloid-positive
individuals
F. Z. Lussier, A. L. Benedet, J. Therriault, T. A. Pascoal, C. Tissot, M. Chamoun, S. Mathotaarachchi, M. Savard, Nicholas J. Ashton, Thomas Karikari, Juan Rodriguez, Anniina Snellman, G. Bezgin, M. S. Kang, J. F. Arias, Y. T. Wang, S. Gauthier, Henrik Zetterberg, Kaj Blennow, P. Rosa-Neto
Brain Communications - 2021 -
A multicentre validation study of the diagnostic value of plasma neurofilament
light.
Nicholas J. Ashton, Shorena Janelidze, Ahmad Al Khleifat, Antoine Leuzy, Emma L van der Ende, Thomas Karikari, Andrea L Benedet, Tharick A Pascoal, Alberto Lleó, Lucilla Parnetti, Daniela Galimberti, Laura Bonanni, Andrea Pilotto, Alessandro Padovani, Jan Lycke, Lenka Novakova, Markus Axelsson, Latha Velayudhan, Gil D Rabinovici, Bruce Miller, Carmine Pariante, Naghmeh Nikkheslat, Susan M Resnick, Madhav Thambisetty, Michael Schöll, Gorka Fernández-Eulate, Francisco J Gil-Bea, Adolfo López de Munain, Ammar Al-Chalabi, Pedro Rosa-Neto, Andre Strydom, Per Svenningsson, Erik Stomrud, Alexander Santillo, Dag Aarsland, John C van Swieten, Sebastian Palmqvist, Henrik Zetterberg, Kaj Blennow, Abdul Hye, Oskar Hansson
Nature communications - 2021 -
Plasma NfL, clinical subtypes and motor progression in Parkinson's
disease
A. Pilotto, A. Imarisio, F. Conforti, A. Scalvini, S. Masciocchi, S. Nocivelli, R. Turrone, S. Gipponi, E. Cottini, B. Borroni, M. C. Rizzetti, M. Pizzi, L. Bonanni, A. Sturchio, A. J. Espay, Henrik Zetterberg, Nicholas J. Ashton, A. Hye, A. Padovani
Parkinsonism & Related Disorders - 2021 -
The strategic biomarker roadmap for the validation of Alzheimer's diagnostic biomarkers: methodological
update
M. Boccardi, A. Dodich, E. Albanese, A. Gayet-Ageron, C. Festari, Nicholas J. Ashton, G. N. Bischof, K. Chiotis, A. Leuzy, E. E. Wolters, M. A. Walter, G. D. Rabinovici, M. Carrillo, A. Drzezga, O. Hansson, A. Nordberg, R. Ossenkoppele, V. L. Villemagne, B. Winblad, G. B. Frisoni, V. Garibotto
European Journal of Nuclear Medicine and Molecular Imaging - 2021 -
The validation status of blood biomarkers of amyloid and phospho-tau assessed with the 5-phase development framework for AD
biomarkers
Nicholas J. Ashton, A. Leuzy, Thomas Karikari, N. Mattsson-Carlgren, A. Dodich, M. Boccardi, J. Corre, A. Drzezga, A. Nordberg, R. Ossenkoppele, Henrik Zetterberg, Kaj Blennow, G. B. Frisoni, V. Garibotto, O. Hansson
European Journal of Nuclear Medicine and Molecular Imaging - 2021 -
2020 update on the clinical validity of cerebrospinal fluid amyloid, tau, and phospho-tau as biomarkers for Alzheimer's disease in the context of a structured 5-phase development
framework
A. Leuzy, Nicholas J. Ashton, N. Mattsson-Carlgren, A. Dodich, M. Boccardi, J. Corre, A. Drzezga, A. Nordberg, R. Ossenkoppele, Henrik Zetterberg, Kaj Blennow, G. B. Frisoni, V. Garibotto, O. Hansson
European Journal of Nuclear Medicine and Molecular Imaging - 2021 -
Plasma p-tau231: a new biomarker for incipient Alzheimer's disease
pathology.
Nicholas J. Ashton, Tharick A Pascoal, Thomas Karikari, Andréa Lessa Benedet, Juan Lantero Rodriguez, Gunnar Brinkmalm, Anniina Snellman, Michael Schöll, Claire Troakes, Abdul Hye, Serge Gauthier, Eugeen Vanmechelen, Henrik Zetterberg, Pedro Rosa-Neto, Kaj Blennow
Acta neuropathologica - 2021 -
Biomarkers for central nervous system injury in cerebrospinal fluid are elevated in COVID-19 and associated with neurological symptoms and disease
severity
J. Virhammar, A. Naas, D. Fallmar, J. L. Cunningham, A. Klang, Nicholas J. Ashton, S. Jackmann, G. Westman, R. Frithiof, Kaj Blennow, Henrik Zetterberg, E. Kumlien, E. Rostami
European Journal of Neurology - 2021 -
Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer
Disease.
Alexis Moscoso Rial, Michel J. Grothe, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, Anniina Snellman, Marc Suárez-Calvet, Kaj Blennow, Henrik Zetterberg, Michael Schöll
JAMA Neurology - 2021 -
Neurofilament light as an outcome predictor after cardiac arrest: a post hoc analysis of the COMACARE
trial
L. Wihersaari, Nicholas J. Ashton, M. Reinikainen, P. Jakkula, V. Pettila, J. Hastbacka, M. Tiainen, P. Loisa, H. Friberg, T. Cronberg, Kaj Blennow, Henrik Zetterberg, M. B. Skrifvars
Intensive Care Medicine - 2021 -
Plasma phospho-tau181 in presymptomatic and symptomatic familial Alzheimer's disease: a longitudinal cohort
study
A. O'Connor, Thomas Karikari, T. Poole, Nicholas J. Ashton, Juan Rodriguez, A. Khatun, I. Swift, A. J. Heslegrave, E. Abel, E. Chung, P. S. J. Weston, I. M. Pavisic, N. S. Ryan, S. Barker, M. N. Rossor, J. M. Polke, C. Frost, S. Mead, Kaj Blennow, Henrik Zetterberg, N. C. Fox
Molecular Psychiatry - 2021 -
CSF Synaptic Biomarkers in the Preclinical Stage of Alzheimer Disease and Their Association With MRI and PET: A Cross-sectional
Study.
Marta Milà-Alomà, Ann Brinkmalm, Nicholas J. Ashton, Hlin Kvartsberg, Mahnaz Shekari, Grégory Operto, Gemma Salvadó, Carles Falcon, Juan Domingo Gispert, Natalia Vilor-Tejedor, Eider M Arenaza-Urquijo, Oriol Grau-Rivera, Aleix Sala-Vila, Gonzalo Sanchez-Benavides, José María González-de-Echávarri, Carolina Minguillon, Karine Fauria, Aida Niñerola-Baizán, Andrés Perissinotti, Gwendlyn Kollmorgen, Ivonne Suridjan, Henrik Zetterberg, José Luis Molinuevo, Kaj Blennow, Marc Suárez-Calvet
Neurology - 2021 -
Effects of pre-analytical procedures on blood biomarkers for Alzheimer's pathophysiology, glial activation, and
neurodegeneration.
Nicholas J. Ashton, Marc Suárez-Calvet, Thomas Karikari, Juan Lantero Rodriguez, Anniina Snellman, Joel Simrén, Carolina Minguillon, Karine Fauria, Kaj Blennow, Henrik Zetterberg
Alzheimer's & dementia (Amsterdam, Netherlands) - 2021 -
Cerebrospinal fluid biomarker panel for synaptic dysfunction in Alzheimer's
disease
Johanna Nilsson, Johan Gobom, Simon Sjödin, Gunnar Brinkmalm, Nicholas J. Ashton, Johan Svensson, Per Johansson, E. Portelius, Henrik Zetterberg, Kaj Blennow, Ann Brinkmalm
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring - 2021 -
Spitting image: can saliva biomarkers reflect Alzheimer's
disease?
Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg
EBioMedicine - 2021 -
Saliva Neurofilament Light Chain Is Not a Diagnostic Biomarker for Neurodegeneration in a Mixed Memory Clinic
Population
H. S. Gleerup, Federica Sanna, P. Hogh, Joel Simrén, Kaj Blennow, Henrik Zetterberg, S. G. Hasselbalch, Nicholas J. Ashton, A. H. Simonsen
Frontiers in Aging Neuroscience - 2021 -
Time course of phosphorylated-tau181 in blood across the Alzheimer's disease
spectrum.
Alexis Moscoso Rial, Michel J. Grothe, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, Anniina Snellman, Marc Suarez-Calvet, Henrik Zetterberg, Kaj Blennow, Michael Schöll
Brain : a journal of neurology - 2021 -
Association between polygenic risk score of Alzheimer's disease and plasma phosphorylated tau in individuals from the Alzheimer's Disease Neuroimaging
Initiative.
Anna Zettergren, Jodie Lord, Nicholas J. Ashton, Andréa Lessa Benedet, Thomas Karikari, Juan Lantero Rodriguez, Anniina Snellman, Marc Suárez-Calvet, Petroula Proitsi, Henrik Zetterberg, Kaj Blennow
Alzheimer's research & therapy - 2021 -
Determining Amyloid-β Positivity Using 18F-AZD4694 PET
Imaging
J. Therriault, A. L. Benedet, T. A. Pascoal, M. Savard, Nicholas J. Ashton, M. Chamoun, C. Tissot, F. Lussier, M. S. Kang, G. Bezgin, T. Wang, J. Fernandes-Arias, G. Massarweh, P. Vitali, Henrik Zetterberg, Kaj Blennow, P. Saha-Chaudhuri, J. P. Soucy, S. Gauthier, P. Rosa-Neto
Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 2021 -
SARS-CoV-2 encephalitis is a cytokine release syndrome: evidences from cerebrospinal fluid
analyses.
Andrea Pilotto, Stefano Masciocchi, Irene Volonghi, Valeria De Giuli, Francesca Caprioli, Sara Mariotto, Sergio Ferrari, Silvia Bozzetti, Alberto Imarisio, Barbara Risi, Enrico Premi, Alberto Benussi, Emanuele Focà, Francesco Castelli, Gianluigi Zanusso, Salvatore Monaco, Paola Stefanelli, Roberto Gasparotti, Anastasia Zekeridou, Andrew McKeon, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Alessandro Padovani
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 2021 -
Plasma GFAP is an early marker of amyloid-β but not tau pathology in Alzheimer's
disease.
Joana B Pereira, Shorena Janelidze, Ruben Smith, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Charlotte E Teunissen, Henrik Zetterberg, Erik Stomrud, Nicholas J. Ashton, Kaj Blennow, Oskar Hansson
Brain : a journal of neurology - 2021 -
Microglial activation and tau propagate jointly across Braak
stages.
Tharick A Pascoal, Andrea L Benedet, Nicholas J. Ashton, Min Su Kang, Joseph Therriault, Mira Chamoun, Melissa Savard, Firoza Z Lussier, Cécile Tissot, Thomas Karikari, Julie Ottoy, Sulantha Mathotaarachchi, Jenna Stevenson, Gassan Massarweh, Michael Schöll, Mony J de Leon, Jean-Paul Soucy, Paul Edison, Kaj Blennow, Henrik Zetterberg, Serge Gauthier, Pedro Rosa-Neto
Nature medicine - 2021 -
Blood Biomarkers for Alzheimer's Disease in Down
Syndrome
Laia Montoliu-Gaya, A. Strydom, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton
Journal of Clinical Medicine - 2021 -
Plasma neurofilament light chain as a potential biomarker in Charcot-Marie-Tooth
disease.
Elina Millere, Dmitrijs Rots, Joel Simrén, Nicholas J. Ashton, Einars Kupats, Ieva Micule, Viktorija Priedite, Natalja Kurjane, Kaj Blennow, Linda Gailite, Henrik Zetterberg, Viktorija Kenina
European journal of neurology - 2021 -
Comparison of Plasma Phosphorylated Tau Species With Amyloid and Tau Positron Emission Tomography, Neurodegeneration, Vascular Pathology, and Cognitive
Outcomes
M. M. Mielke, R. D. Frank, J. L. Dage, A. Jeromin, Nicholas J. Ashton, Kaj Blennow, Thomas Karikari, E. Vanmechelen, Henrik Zetterberg, A. Algeciras-Schimnich, D. S. Knopman, V. Lowe, G. J. Bu, P. Vemuri, J. Graff-Radford, C. R. Jack, R. C. Petersen
JAMA Neurology - 2021 -
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer's Disease Neuroimaging
Initiative.
Thomas Karikari, Andréa L Benedet, Nicholas J. Ashton, Juan Lantero Rodriguez, Anniina Snellman, Marc Suárez-Calvet, Paramita Saha-Chaudhuri, Firoza Lussier, Hlin Kvartsberg, Alexis Moscoso Rial, Tharick A Pascoal, Ulf Andreasson, Michael Schöll, Michael W Weiner, Pedro Rosa-Neto, John Q Trojanowski, Leslie M Shaw, Kaj Blennow, Henrik Zetterberg
Molecular psychiatry - 2021 -
Critical illness polyneuropathy, myopathy and neuronal biomarkers in COVID-19 patients: A prospective
study
R. Frithiof, E. Rostami, E. Kumlien, J. Virhammar, D. Fallmar, M. Hultstrom, M. Lipcsey, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, A. R. Punga
Clinical Neurophysiology - 2021 -
Use of plasma biomarkers for AT(N) classification of neurodegenerative
dementias
D. Alcolea, C. Delaby, L. Muñoz, S. Torres, T. Estellés, N. Zhu, I. Barroeta, M. Carmona-Iragui, I. Illán-Gala, M. Á Santos-Santos, M. Altuna, I. Sala, Mª B. Sánchez-Saudinós, L. Videla, S. Valldeneu, A. Subirana, J. Pegueroles, C. Hirtz, J. Vialaret, S. Lehmann, Thomas Karikari, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, O. Belbin, R. Blesa, J. Clarimón, J. Fortea, A. Lleó
Journal of Neurology, Neurosurgery and Psychiatry - 2021 -
Publisher Correction: Microglial activation and tau propagate jointly across Braak
stages.
Tharick A Pascoal, Andréa Lessa Benedet, Nicholas J. Ashton, Min Su Kang, Joseph Therriault, Mira Chamoun, Melissa Savard, Firoza Z Lussier, Cécile Tissot, Thomas Karikari, Julie Ottoy, Sulantha Mathotaarachchi, Jenna Stevenson, Gassan Massarweh, Michael Schöll, Mony J de Leon, Jean-Paul Soucy, Paul Edison, Kaj Blennow, Henrik Zetterberg, Serge Gauthier, Pedro Rosa-Neto
Nature medicine - 2021 -
Serum Hepcidin Levels in Cognitively Normal Older Adults with High Neocortical Amyloid-beta
Load
P. Chatterjee, M. Mohammadi, K. Goozee, T. M. Shah, H. R. Sohrabi, C. B. Dias, K. K. Shen, P. R. Asih, P. Dave, S. Pedrini, Nicholas J. Ashton, A. Hye, K. Taddei, D. B. Lovejoy, Henrik Zetterberg, Kaj Blennow, R. N. Martins
Journal of Alzheimers Disease - 2020 -
Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease
Pathology.
Liu Shi, Laura M Winchester, Benjamine Y Liu, Richard Killick, Elena M Ribe, Sarah Westwood, Alison L Baird, Noel J Buckley, Shengjun Hong, Valerija Dobricic, Fabian Kilpert, Andre Franke, Steven Kiddle, Martina Sattlecker, Richard Dobson, Antonio Cuadrado, Abdul Hye, Nicholas J. Ashton, Angharad R Morgan, Isabelle Bos, Stephanie J B Vos, Mara Ten Kate, Philip Scheltens, Rik Vandenberghe, Silvy Gabel, Karen Meersmans, Sebastiaan Engelborghs, Ellen E De Roeck, Kristel Sleegers, Giovanni B Frisoni, Olivier Blin, Jill C Richardson, Régis Bordet, José L Molinuevo, Lorena Rami, Anders Wallin, Petronella Kettunen, Magda Tsolaki, Frans Verhey, Alberto Lleó, Daniel Alcolea, Julius Popp, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Peter Johannsen, Charlotte E Teunissen, Yvonne Freund-Levi, Lutz Frölich, Cristina Legido-Quigley, Frederik Barkhof, Kaj Blennow, Katrine Laura Rasmussen, Børge Grønne Nordestgaard, Ruth Frikke-Schmidt, Sune Fallgaard Nielsen, Hilkka Soininen, Bruno Vellas, Iwona Kloszewska, Patrizia Mecocci, Henrik Zetterberg, B Paul Morgan, Johannes Streffer, Pieter Jelle Visser, Lars Bertram, Alejo J Nevado-Holgado, Simon Lovestone
Journal of Alzheimer's disease : JAD - 2020 -
Neurochemical evidence of astrocytic and neuronal injury commonly found in
COVID-19.
Nelly Kanberg, Nicholas J. Ashton, Lars-Magnus Andersson, Aylin Yilmaz, Magnus Lindh, Staffan Nilsson, Richard W Price, Kaj Blennow, Henrik Zetterberg, Magnus Gisslén
Neurology - 2020 -
Plasma p-tau181 accurately predicts Alzheimer's disease pathology at least 8 years prior to post-mortem and improves the clinical characterisation of cognitive
decline.
Juan Lantero Rodriguez, Thomas Karikari, Marc Suárez-Calvet, Claire Troakes, Andrew King, Andreja Emersic, Dag Aarsland, Abdul Hye, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton
Acta neuropathologica - 2020 -
Stage-specific links between plasma neurofilament light and imaging biomarkers of Alzheimer's
disease.
Andréa Lessa Benedet, Antoine Leuzy, Nicholas J. Ashton, Sulantha Mathotaarachchi, Melissa Savard, Joseph Therriault, Min Su Kang, Mira Chamoun, Michael Schöll, Eduardo R Zimmer, Serge Gauthier, Aurélie Labbe, Henrik Zetterberg, Pedro Rosa-Neto, Kaj Blennow
Brain : a journal of neurology - 2020 -
Full-length and C-terminal neurogranin in Alzheimer's disease cerebrospinal fluid analyzed by novel ultrasensitive
immunoassays
Annika Öhrfelt, J. Dumurgier, Henrik Zetterberg, A. Vrillon, Nicholas J. Ashton, Hlin Kvartsberg, E. Bouaziz-Amar, J. Hugon, C. Paquet, Kaj Blennow
Alzheimers Research & Therapy - 2020 -
Urinary metabolic phenotyping for Alzheimer's
disease
N. Kurbatova, M. Garg, L. Whiley, E. Chekmeneva, B. Jimenez, M. Gomez-Romero, J. Pearce, T. Kimhofer, E. D'Hondt, H. Soininen, I. Kloszewska, P. Mecocci, M. Tsolaki, B. Vellas, D. Aarsland, A. Nevado-Holgado, B. Liu, S. Snowden, P. Proitsi, Nicholas J. Ashton, A. Hye, C. Legido-Quigley, M. R. Lewis, J. K. Nicholson, E. Holmes, A. Brazma, S. Lovestone
Scientific Reports - 2020 -
Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer's continuum when only subtle changes in Aβ pathology are
detected.
Marc Suárez-Calvet, Thomas Karikari, Nicholas J. Ashton, Juan Lantero Rodriguez, Marta Milà-Alomà, Juan Domingo Gispert, Gemma Salvadó, Carolina Minguillon, Karine Fauria, Mahnaz Shekari, Oriol Grau-Rivera, Eider M Arenaza-Urquijo, Aleix Sala-Vila, Gonzalo Sánchez-Benavides, José Maria González-de-Echávarri, Gwendlyn Kollmorgen, Erik Stoops, Eugeen Vanmechelen, Henrik Zetterberg, Kaj Blennow, José Luis Molinuevo
EMBO molecular medicine - 2020 -
An update on blood-based biomarkers for non-Alzheimer neurodegenerative
disorders.
Nicholas J. Ashton, Abdul Hye, Anto P Rajkumar, Antoine Leuzy, Stuart Snowden, Marc Suárez-Calvet, Thomas Karikari, Michael Schöll, Renaud La Joie, Gil D Rabinovici, Kina Höglund, Clive Ballard, Tibor Hortobágyi, Per Svenningsson, Kaj Blennow, Henrik Zetterberg, Dag Aarsland
Nature Reviews Neurology - 2020 -
Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery
Cohort.
Sarah Westwood, Alison L Baird, Sneha N Anand, Alejo J Nevado-Holgado, Andrey Kormilitzin, Liu Shi, Abdul Hye, Nicholas J. Ashton, Angharad R Morgan, Isabelle Bos, Stephanie J B Vos, Susan Baker, Noel J Buckley, Mara Ten Kate, Philip Scheltens, Charlotte E Teunissen, Rik Vandenberghe, Silvy Gabel, Karen Meersmans, Sebastiaan Engelborghs, Ellen E De Roeck, Kristel Sleegers, Giovanni B Frisoni, Olivier Blin, Jill C Richardson, Régis Bordet, José L Molinuevo, Lorena Rami, Anders Wallin, Petronella Kettunen, Magda Tsolaki, Frans Verhey, Alberto Lléo, Isabel Sala, Julius Popp, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Peter Johannsen, Yvonne Freund-Levi, Lutz Frölich, Valerija Dobricic, Cristina Legido-Quigley, Lars Bertram, Frederik Barkhof, Henrik Zetterberg, B Paul Morgan, Johannes Streffer, Pieter Jelle Visser, Simon Lovestone
Journal of Alzheimer's disease : JAD - 2020 -
Perspectives in fluid biomarkers in neurodegeneration from the 2019 biomarkers in neurodegenerative diseases course-a joint PhD student course at University College London and University of
Gothenburg.
Pawel Obrocki, Ayesha Khatun, Deborah Ness, Konstantin Senkevich, Jörg Hanrieder, Federica Capraro, Niklas Mattsson, Ulf Andreasson, Erik Portelius, Nicholas J. Ashton, Kaj Blennow, Michael Schöll, Ross W Paterson, Jonathan M Schott, Henrik Zetterberg
Alzheimer's research & therapy - 2020 -
Fluid Biomarkers for Synaptic Dysfunction and
Loss
Elena Camporesi, Johanna Nilsson, Ann Brinkmalm, Bruno Becker, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg
Biomarker Insights - 2020 -
Propagation of Tau Pathology: Integrating Insights From Postmortem and In Vivo
Studies.
Thomas Vogels, Antoine Leuzy, Claudia Cicognola, Nicholas J. Ashton, Tomas Smolek, Michal Novak, Kaj Blennow, Henrik Zetterberg, Tomas Hromadka, Norbert Zilka, Michael Schöll
Biological psychiatry - 2020 -
An update on fluid biomarkers for neurodegenerative diseases: recent success and challenges
ahead.
Joel Simrén, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg
Current opinion in neurobiology - 2020 -
Comparing Glial Fibrillary Acidic Protein (GFAP) in Serum and Plasma Following Mild Traumatic Brain Injury in Older
Adults.
Nathan A Huebschmann, Teemu M Luoto, Justin E Karr, Ksenia Berghem, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Joel Simrén, Jussi P Posti, Jessica M Gill, Grant L Iverson
Frontiers in neurology - 2020 -
Relevance of biomarkers across different
neurodegenerative.
Alexander J Ehrenberg, Ayesha Khatun, Emma Coomans, Matthew J Betts, Federica Capraro, Elisabeth H Thijssen, Konstantin Senkevich, Tehmina Bharucha, Mehrsa Jafarpour, Peter N E Young, William Jagust, Stephen F Carter, Tammaryn Lashley, Lea T Grinberg, Joana B Pereira, Niklas Mattsson-Carlgren, Nicholas J. Ashton, Jörg Hanrieder, Henrik Zetterberg, Michael Schöll, Ross W Paterson
Alzheimer's research & therapy - 2020 -
Diagnostic and prognostic value of serum NfL and p-Tau181 in frontotemporal lobar
degeneration.
Alberto Benussi, Thomas Karikari, Nicholas J. Ashton, Stefano Gazzina, Enrico Premi, Luisa Benussi, Roberta Ghidoni, Juan Lantero Rodriguez, Andreja Emersic, Joel Simrén, Giuliano Binetti, Silvia Fostinelli, Marcello Giunta, Roberto Gasparotti, Henrik Zetterberg, Kaj Blennow, Barbara Borroni
Journal of neurology, neurosurgery, and psychiatry - 2020 -
Serum Glial Fibrillary Acidic Protein (GFAP) Is a Marker of Disease Severity in Frontotemporal Lobar
Degeneration.
Alberto Benussi, Nicholas J. Ashton, Thomas Karikari, Stefano Gazzina, Enrico Premi, Luisa Benussi, Roberta Ghidoni, Juan Lantero Rodriguez, Andreja Emersic, Giuliano Binetti, Silvia Fostinelli, Marcello Giunta, Roberto Gasparotti, Henrik Zetterberg, Kaj Blennow, Barbara Borroni
Journal of Alzheimer's disease : JAD - 2020 -
Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective
cohorts.
Thomas Karikari, Tharick A Pascoal, Nicholas J. Ashton, Shorena Janelidze, Andréa Lessa Benedet, Juan Lantero Rodriguez, Mira Chamoun, Melissa Savard, Min Su Kang, Joseph Therriault, Michael Schöll, Gassan Massarweh, Jean-Paul Soucy, Kina Höglund, Gunnar Brinkmalm, Niklas Mattsson, Sebastian Palmqvist, Serge Gauthier, Erik Stomrud, Henrik Zetterberg, Oskar Hansson, Pedro Rosa-Neto, Kaj Blennow
The Lancet. Neurology - 2020 -
Steroid-Responsive Encephalitis in Coronavirus Disease
2019
A. Pilotto, S. Odolini, S. Masciocchi, A. Comelli, I. Volonghi, S. Gazzina, S. Nocivelli, A. Pezzini, E. Foca, A. Caruso, M. Leonardi, M. P. Pasolini, R. Gasparotti, F. Castelli, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, A. Padovani
Annals of Neurology - 2020 -
Plasma transferrin and hemopexin are associated with altered A beta uptake and cognitive decline in Alzheimer's disease
pathology
A. Ashraf, Nicholas J. Ashton, P. Chatterjee, K. Goozee, K. K. Shen, J. Fripp, D. Ames, C. Rowe, C. L. Masters, V. Villemagne, A. Hye, R. N. Martins, P. W. So
Alzheimers Research & Therapy - 2020 -
Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan
assay.
Liu Shi, Sarah Westwood, Alison L Baird, Laura Winchester, Valerija Dobricic, Fabian Kilpert, Shengjun Hong, Andre Franke, Abdul Hye, Nicholas J. Ashton, Angharad R Morgan, Isabelle Bos, Stephanie J B Vos, Noel J Buckley, Mara Ten Kate, Philip Scheltens, Rik Vandenberghe, Silvy Gabel, Karen Meersmans, Sebastiaan Engelborghs, Ellen E De Roeck, Kristel Sleegers, Giovanni B Frisoni, Olivier Blin, Jill C Richardson, Régis Bordet, José L Molinuevo, Lorena Rami, Anders Wallin, Petronella Kettunen, Magda Tsolaki, Frans Verhey, Alberto Lleó, Daniel Alcolea, Julius Popp, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Peter Johannsen, Charlotte E Teunissen, Yvonne Freund-Levi, Lutz Frölich, Cristina Legido-Quigley, Frederik Barkhof, Kaj Blennow, Henrik Zetterberg, Susan Baker, B Paul Morgan, Johannes Streffer, Pieter Jelle Visser, Lars Bertram, Simon Lovestone, Alejo J Nevado-Holgado
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2019 -
Biomarkers for tau
pathology.
Michael Schöll, Anne Maass, Niklas Mattsson, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, William Jagust
Molecular and cellular neurosciences - 2019 -
A plasma protein classifier for predicting amyloid burden for preclinical Alzheimer's
disease.
Nicholas J. Ashton, Alejo J Nevado-Holgado, Imelda S Barber, Steven Lynham, Veer Gupta, Pratishtha Chatterjee, Kathryn Goozee, Eugene Hone, Steve Pedrini, Kaj Blennow, Michael Schöll, Henrik Zetterberg, Kathryn A Ellis, Ashley I Bush, Christopher C Rowe, Victor L Villemagne, David Ames, Colin L Masters, Dag Aarsland, John Powell, Simon Lovestone, Ralph Martins, Abdul Hye
Science advances - 2019 -
Synaptic vesicle protein 2A as a potential biomarker in
synaptopathies.
Kerstin Heurling, Nicholas J. Ashton, Antoine Leuzy, Eduardo R Zimmer, Kaj Blennow, Henrik Zetterberg, Jonas Eriksson, Mark Lubberink, Michael Schöll
Molecular and cellular neurosciences - 2019 -
Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and
neurodegeneration.
Nicholas J. Ashton, Antoine Leuzy, Yau Mun Lim, Claire Troakes, Tibor Hortobágyi, Kina Höglund, Dag Aarsland, Simon Lovestone, Michael Schöll, Kaj Blennow, Henrik Zetterberg, Abdul Hye
Acta neuropathologica communications - 2019 -
Comparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and
serum.
Meenu Rohin Rajan, Matus Sotak, Fredrik Barrenäs, Tong Shen, Kamil Borkowski, Nicholas J. Ashton, Christina Biörserud, Tomas L Lindahl, Sofia Ramström, Michael Schöll, Per Lindahl, Oliver Fiehn, John W Newman, Rosie Perkins, Ville Wallenius, Stephan Lange, Emma Börgeson
Scientific reports - 2019 -
Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer's
disease.
Pratishtha Chatterjee, Henrik Zetterberg, Kathryn Goozee, Chai K Lim, Kelly R Jacobs, Nicholas J. Ashton, Abdul Hye, Steve Pedrini, Hamid R Sohrabi, Tejal Shah, Prita R Asih, Preeti Dave, Kaikai Shen, Kevin Taddei, David B Lovejoy, Gilles J Guillemin, Kaj Blennow, Ralph N Martins
Journal of neuroinflammation - 2019 -
Plasma neurofilament light associates with Alzheimer's disease metabolic decline in amyloid-positive
individuals.
Andréa L Benedet, Nicholas J. Ashton, Tharick A Pascoal, Antoine Leuzy, Sulantha Mathotaarachchi, Min S Kang, Joseph Therriault, Melissa Savard, Mira Chamoun, Michael Schöll, Eduardo R Zimmer, Serge Gauthier, Aurélie Labbe, Henrik Zetterberg, Kaj Blennow, Pedro R Neto
Alzheimer's & dementia - 2019 -
Salivary Biomarkers for Alzheimer's Disease and Related
Disorders.
Nicholas J. Ashton, Mark Ide, Henrik Zetterberg, Kaj Blennow
Neurology and therapy - 2019 -
Plasma levels of soluble TREM2 and neurofilament light chain in TREM2 rare variant
carriers.
Nicholas J. Ashton, Marc Suarez-Calvet, Amanda Heslegrave, Abdul Hye, Cristina Razquin, Pau Pastor, Raquel Sanchez-Valle, José L Molinuevo, Pieter Jelle Visser, Kaj Blennow, Angela K Hodges, Henrik Zetterberg
Alzheimer's research & therapy - 2019 -
Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery
cohort.
Min Kim, Stuart Snowden, Tommi Suvitaival, Ashfaq Ali, David J Merkler, Tahmina Ahmad, Sarah Westwood, Alison Baird, Petroula Proitsi, Alejo Nevado-Holgado, Abdul Hye, Isabelle Bos, Stephanie Vos, Rik Vandenberghe, Charlotte Teunissen, Mara Ten Kate, Philip Scheltens, Silvy Gabel, Karen Meersmans, Olivier Blin, Jill Richardson, Ellen De Roeck, Kristel Sleegers, Régis Bordet, Lorena Rami, Petronella Kettunen, Magda Tsolaki, Frans Verhey, Isabel Sala, Alberto Lléo, Gwendoline Peyratout, Mikel Tainta, Peter Johannsen, Yvonne Freund-Levi, Lutz Frölich, Valerija Dobricic, Sebastiaan Engelborghs, Giovanni B Frisoni, José L Molinuevo, Anders Wallin, Julius Popp, Pablo Martinez-Lage, Lars Bertram, Frederik Barkhof, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Johannes Streffer, Pieter J Visser, Simon Lovestone, Cristina Legido-Quigley
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2019 -
Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's
disease
C. M. Startin, Nicholas J. Ashton, S. Hamburg, R. Hithersay, F. K. Wiseman, K. Y. Mok, J. Hardy, A. Lleo, S. Lovestone, L. Parnetti, Henrik Zetterberg, A. Hye, E. Fisher, D. Nizetic, J. Hardy, R. L. Weston, V. Tybulewicz, A. Karmiloff-Smith, A. Strydom, Ajmg V. P. Vani S
Alzheimers Research & Therapy - 2019 -
In vivo Detection of Alzheimer's
Disease.
Antoine Leuzy, Kerstin Heurling, Nicholas J. Ashton, Michael Schöll, Eduardo R Zimmer
The Yale journal of biology and medicine - 2018 -
No association of salivary total tau concentration with Alzheimer's
disease.
Nicholas J. Ashton, Mark Ide, Michael Schöll, Kaj Blennow, Simon Lovestone, Abdul Hye, Henrik Zetterberg
Neurobiology of aging - 2018 -
Plasma Protein Biomarkers for the Prediction of CSF Amyloid and Tau and F-18 -Flutemetamol PET Scan
Result
S. Westwood, A. L. Baird, A. Hye, Nicholas J. Ashton, A. J. Nevado-Holgado, S. N. Anand, B. Liu, D. Newby, C. Bazenet, S. J. Kiddle, M. Ward, B. Newton, K. Desai, C. T. Hehir, M. Zanette, D. Galimberti, L. Parnetti, A. Lleo, S. Baker, V. A. Narayan, W. M. van der Flier, P. Scheltens, C. E. Teunissen, P. J. Visser, S. Lovestone
Frontiers in Aging Neuroscience - 2018 -
Update on biomarkers for amyloid pathology in Alzheimer's
disease
Nicholas J. Ashton, Michael Schöll, Kerstin Heurling, Eleni Gkanatsiou, Erik Portelius, Kina Höglund, Gunnar Brinkmalm, A Hye, Kaj Blennow, Henrik Zetterberg
Biomarkers in medicine - 2018