Nicholas Ashton
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Comparing Glial Fibrillary Acidic Protein (GFAP) in Serum and Plasma Following Mild Traumatic Brain Injury in Older
Adults.
Nathan A Huebschmann, Teemu M Luoto, Justin E Karr, Ksenia Berghem, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Joel Simrén, Jussi P Posti, Jessica M Gill, Grant L Iverson
Frontiers in neurology - 2020-01-01 -
Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective
cohorts.
Thomas Karikari, Tharick A Pascoal, Nicholas J. Ashton, Shorena Janelidze, Andréa Lessa Benedet, Juan Lantero Rodriguez, Mira Chamoun, Melissa Savard, Min Su Kang, Joseph Therriault, Michael Schöll, Gassan Massarweh, Jean-Paul Soucy, Kina Höglund, Gunnar Brinkmalm, Niklas Mattsson, Sebastian Palmqvist, Serge Gauthier, Erik Stomrud, Henrik Zetterberg, Oskar Hansson, Pedro Rosa-Neto, Kaj Blennow
The Lancet. Neurology - 2020-01-01 -
Steroid-Responsive Encephalitis in Coronavirus Disease
2019
A. Pilotto, S. Odolini, S. Masciocchi, A. Comelli, I. Volonghi, S. Gazzina, S. Nocivelli, A. Pezzini, E. Foca, A. Caruso, M. Leonardi, M. P. Pasolini, R. Gasparotti, F. Castelli, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, A. Padovani
Annals of Neurology - 2020-01-01 -
Neurofilament light as an outcome predictor after cardiac arrest: a post hoc analysis of the COMACARE
trial
L. Wihersaari, Nicholas J. Ashton, M. Reinikainen, P. Jakkula, V. Pettila, J. Hastbacka, M. Tiainen, P. Loisa, H. Friberg, T. Cronberg, Kaj Blennow, Henrik Zetterberg, M. B. Skrifvars
Intensive Care Medicine - 2020-01-01 -
Fluid Biomarkers for Synaptic Dysfunction and
Loss
Elena Camporesi, Johanna Nilsson, Ann Brinkmalm, Bruno Becker, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg
Biomarker Insights - 2020-01-01 -
Relevance of biomarkers across different
neurodegenerative.
Alexander J Ehrenberg, Ayesha Khatun, Emma Coomans, Matthew J Betts, Federica Capraro, Elisabeth H Thijssen, Konstantin Senkevich, Tehmina Bharucha, Mehrsa Jafarpour, Peter N E Young, William Jagust, Stephen F Carter, Tammaryn Lashley, Lea T Grinberg, Joana B Pereira, Niklas Mattsson-Carlgren, Nicholas J. Ashton, Jörg Hanrieder, Henrik Zetterberg, Michael Schöll, Ross W Paterson
Alzheimer's research & therapy - 2020-01-01 -
Plasma p-tau181 accurately predicts Alzheimer's disease pathology at least 8 years prior to post-mortem and improves the clinical characterisation of cognitive
decline.
Juan Lantero Rodriguez, Thomas Karikari, Marc Suárez-Calvet, Claire Troakes, Andrew King, Andreja Emersic, Dag Aarsland, Abdul Hye, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton
Acta neuropathologica - 2020-01-01 -
Diagnostic and prognostic value of serum NfL and p-Tau181 in frontotemporal lobar
degeneration.
Alberto Benussi, Thomas Karikari, Nicholas J. Ashton, Stefano Gazzina, Enrico Premi, Luisa Benussi, Roberta Ghidoni, Juan Lantero Rodriguez, Andreja Emeršič, Joel Simrén, Giuliano Binetti, Silvia Fostinelli, Marcello Giunta, Roberto Gasparotti, Henrik Zetterberg, Kaj Blennow, Barbara Borroni
Journal of neurology, neurosurgery, and psychiatry - 2020-01-01 -
Plasma phospho-tau181 in presymptomatic and symptomatic familial Alzheimer's disease: a longitudinal cohort
study
A. O'Connor, Thomas Karikari, T. Poole, Nicholas J. Ashton, Juan Rodriguez, A. Khatun, I. Swift, A. J. Heslegrave, E. Abel, E. Chung, P. S. J. Weston, I. M. Pavisic, N. S. Ryan, S. Barker, M. N. Rossor, J. M. Polke, C. Frost, S. Mead, Kaj Blennow, Henrik Zetterberg, N. C. Fox
Molecular Psychiatry - 2020-01-01 -
Serum Hepcidin Levels in Cognitively Normal Older Adults with High Neocortical Amyloid-beta
Load
P. Chatterjee, M. Mohammadi, K. Goozee, T. M. Shah, H. R. Sohrabi, C. B. Dias, K. K. Shen, P. R. Asih, P. Dave, S. Pedrini, Nicholas J. Ashton, A. Hye, K. Taddei, D. B. Lovejoy, Henrik Zetterberg, Kaj Blennow, R. N. Martins
Journal of Alzheimers Disease - 2020-01-01 -
Plasma transferrin and hemopexin are associated with altered A beta uptake and cognitive decline in Alzheimer's disease
pathology
A. Ashraf, Nicholas J. Ashton, P. Chatterjee, K. Goozee, K. K. Shen, J. Fripp, D. Ames, C. Rowe, C. L. Masters, V. Villemagne, A. Hye, R. N. Martins, P. W. So
Alzheimers Research & Therapy - 2020-01-01 -
An update on fluid biomarkers for neurodegenerative diseases: recent success and challenges
ahead.
Joel Simrén, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg
Current opinion in neurobiology - 2020-01-01 -
Propagation of Tau Pathology: Integrating Insights From Postmortem and In Vivo
Studies.
Thomas Vogels, Antoine Leuzy, Claudia Cicognola, Nicholas J. Ashton, Tomas Smolek, Michal Novak, Kaj Blennow, Henrik Zetterberg, Tomas Hromadka, Norbert Zilka, Michael Schöll
Biological psychiatry - 2020-01-01 -
Perspectives in fluid biomarkers in neurodegeneration from the 2019 biomarkers in neurodegenerative diseases course-a joint PhD student course at University College London and University of
Gothenburg.
Pawel Obrocki, Ayesha Khatun, Deborah Ness, Konstantin Senkevich, Jörg Hanrieder, Federica Capraro, Niklas Mattsson, Ulf Andreasson, Erik Portelius, Nicholas J. Ashton, Kaj Blennow, Michael Schöll, Ross W Paterson, Jonathan M Schott, Henrik Zetterberg
Alzheimer's research & therapy - 2020-01-01 -
Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery
Cohort.
Sarah Westwood, Alison L Baird, Sneha N Anand, Alejo J Nevado-Holgado, Andrey Kormilitzin, Liu Shi, Abdul Hye, Nicholas J. Ashton, Angharad R Morgan, Isabelle Bos, Stephanie J B Vos, Susan Baker, Noel J Buckley, Mara Ten Kate, Philip Scheltens, Charlotte E Teunissen, Rik Vandenberghe, Silvy Gabel, Karen Meersmans, Sebastiaan Engelborghs, Ellen E De Roeck, Kristel Sleegers, Giovanni B Frisoni, Olivier Blin, Jill C Richardson, Régis Bordet, José L Molinuevo, Lorena Rami, Anders Wallin, Petronella Kettunen, Magda Tsolaki, Frans Verhey, Alberto Lléo, Isabel Sala, Julius Popp, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Peter Johannsen, Yvonne Freund-Levi, Lutz Frölich, Valerija Dobricic, Cristina Legido-Quigley, Lars Bertram, Frederik Barkhof, Henrik Zetterberg, B Paul Morgan, Johannes Streffer, Pieter Jelle Visser, Simon Lovestone
Journal of Alzheimer's disease : JAD - 2020-01-01 -
An update on blood-based biomarkers for non-Alzheimer neurodegenerative
disorders.
Nicholas J. Ashton, Abdul Hye, Anto P Rajkumar, Antoine Leuzy, Stuart Snowden, Marc Suárez-Calvet, Thomas Karikari, Michael Schöll, Renaud La Joie, Gil D Rabinovici, Kina Höglund, Clive Ballard, Tibor Hortobágyi, Per Svenningsson, Kaj Blennow, Henrik Zetterberg, Dag Aarsland
Nature Reviews Neurology - 2020-01-01 -
Comparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and
serum.
Meenu Rohin Rajan, Matus Sotak, Fredrik Barrenäs, Tong Shen, Kamil Borkowski, Nicholas J. Ashton, Christina Biörserud, Tomas L Lindahl, Sofia Ramström, Michael Schöll, Per Lindahl, Oliver Fiehn, John W Newman, Rosie Perkins, Ville Wallenius, Stephan Lange, Emma Börgeson
Scientific reports - 2019-01-01 -
Salivary Biomarkers for Alzheimer's Disease and Related
Disorders.
Nicholas J. Ashton, Mark Ide, Henrik Zetterberg, Kaj Blennow
Neurology and therapy - 2019-01-01 -
Plasma levels of soluble TREM2 and neurofilament light chain in TREM2 rare variant
carriers.
Nicholas J. Ashton, Marc Suarez-Calvet, Amanda Heslegrave, Abdul Hye, Cristina Razquin, Pau Pastor, Raquel Sanchez-Valle, José L Molinuevo, Pieter Jelle Visser, Kaj Blennow, Angela K Hodges, Henrik Zetterberg
Alzheimer's research & therapy - 2019-01-01 -
Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer's
disease.
Pratishtha Chatterjee, Henrik Zetterberg, Kathryn Goozee, Chai K Lim, Kelly R Jacobs, Nicholas J. Ashton, Abdul Hye, Steve Pedrini, Hamid R Sohrabi, Tejal Shah, Prita R Asih, Preeti Dave, Kaikai Shen, Kevin Taddei, David B Lovejoy, Gilles J Guillemin, Kaj Blennow, Ralph N Martins
Journal of neuroinflammation - 2019-01-01 -
Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan
assay.
Liu Shi, Sarah Westwood, Alison L Baird, Laura Winchester, Valerija Dobricic, Fabian Kilpert, Shengjun Hong, Andre Franke, Abdul Hye, Nicholas J. Ashton, Angharad R Morgan, Isabelle Bos, Stephanie J B Vos, Noel J Buckley, Mara Ten Kate, Philip Scheltens, Rik Vandenberghe, Silvy Gabel, Karen Meersmans, Sebastiaan Engelborghs, Ellen E De Roeck, Kristel Sleegers, Giovanni B Frisoni, Olivier Blin, Jill C Richardson, Régis Bordet, José L Molinuevo, Lorena Rami, Anders Wallin, Petronella Kettunen, Magda Tsolaki, Frans Verhey, Alberto Lleó, Daniel Alcolea, Julius Popp, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Peter Johannsen, Charlotte E Teunissen, Yvonne Freund-Levi, Lutz Frölich, Cristina Legido-Quigley, Frederik Barkhof, Kaj Blennow, Henrik Zetterberg, Susan Baker, B Paul Morgan, Johannes Streffer, Pieter Jelle Visser, Lars Bertram, Simon Lovestone, Alejo J Nevado-Holgado
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2019-01-01 -
Synaptic vesicle protein 2A as a potential biomarker in
synaptopathies.
Kerstin Heurling, Nicholas J. Ashton, Antoine Leuzy, Eduardo R Zimmer, Kaj Blennow, Henrik Zetterberg, Jonas Eriksson, Mark Lubberink, Michael Schöll
Molecular and cellular neurosciences - 2019-01-01 -
Plasma neurofilament light associates with Alzheimer's disease metabolic decline in amyloid-positive
individuals.
Andréa L Benedet, Nicholas J. Ashton, Tharick A Pascoal, Antoine Leuzy, Sulantha Mathotaarachchi, Min S Kang, Joseph Therriault, Melissa Savard, Mira Chamoun, Michael Schöll, Eduardo R Zimmer, Serge Gauthier, Aurélie Labbe, Henrik Zetterberg, Kaj Blennow, Pedro R Neto
Alzheimer's & dementia - 2019-01-01 -
Biomarkers for tau
pathology.
Michael Schöll, Anne Maass, Niklas Mattsson, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, William Jagust
Molecular and cellular neurosciences - 2019-01-01 -
Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery
cohort.
Min Kim, Stuart Snowden, Tommi Suvitaival, Ashfaq Ali, David J Merkler, Tahmina Ahmad, Sarah Westwood, Alison Baird, Petroula Proitsi, Alejo Nevado-Holgado, Abdul Hye, Isabelle Bos, Stephanie Vos, Rik Vandenberghe, Charlotte Teunissen, Mara Ten Kate, Philip Scheltens, Silvy Gabel, Karen Meersmans, Olivier Blin, Jill Richardson, Ellen De Roeck, Kristel Sleegers, Régis Bordet, Lorena Rami, Petronella Kettunen, Magda Tsolaki, Frans Verhey, Isabel Sala, Alberto Lléo, Gwendoline Peyratout, Mikel Tainta, Peter Johannsen, Yvonne Freund-Levi, Lutz Frölich, Valerija Dobricic, Sebastiaan Engelborghs, Giovanni B Frisoni, José L Molinuevo, Anders Wallin, Julius Popp, Pablo Martinez-Lage, Lars Bertram, Frederik Barkhof, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Johannes Streffer, Pieter J Visser, Simon Lovestone, Cristina Legido-Quigley
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2019-01-01 -
Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's
disease
C. M. Startin, Nicholas J. Ashton, S. Hamburg, R. Hithersay, F. K. Wiseman, K. Y. Mok, J. Hardy, A. Lleo, S. Lovestone, L. Parnetti, Henrik Zetterberg, A. Hye, E. Fisher, D. Nizetic, J. Hardy, R. L. Weston, V. Tybulewicz, A. Karmiloff-Smith, A. Strydom, Ajmg V. P. Vani S
Alzheimers Research & Therapy - 2019-01-01 -
A plasma protein classifier for predicting amyloid burden for preclinical Alzheimer's
disease.
Nicholas J. Ashton, Alejo J Nevado-Holgado, Imelda S Barber, Steven Lynham, Veer Gupta, Pratishtha Chatterjee, Kathryn Goozee, Eugene Hone, Steve Pedrini, Kaj Blennow, Michael Schöll, Henrik Zetterberg, Kathryn A Ellis, Ashley I Bush, Christopher C Rowe, Victor L Villemagne, David Ames, Colin L Masters, Dag Aarsland, John Powell, Simon Lovestone, Ralph Martins, Abdul Hye
Science advances - 2019-01-01 -
Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and
neurodegeneration.
Nicholas J. Ashton, Antoine Leuzy, Yau Mun Lim, Claire Troakes, Tibor Hortobágyi, Kina Höglund, Dag Aarsland, Simon Lovestone, Michael Schöll, Kaj Blennow, Henrik Zetterberg, Abdul Hye
Acta neuropathologica communications - 2019-01-01 -
No association of salivary total tau concentration with Alzheimer's
disease.
Nicholas J. Ashton, Mark Ide, Michael Schöll, Kaj Blennow, Simon Lovestone, Abdul Hye, Henrik Zetterberg
Neurobiology of aging - 2018-01-01 -
In vivo Detection of Alzheimer's
Disease.
Antoine Leuzy, Kerstin Heurling, Nicholas J. Ashton, Michael Schöll, Eduardo R Zimmer
The Yale journal of biology and medicine - 2018-01-01 -
Plasma Protein Biomarkers for the Prediction of CSF Amyloid and Tau and F-18 -Flutemetamol PET Scan
Result
S. Westwood, A. L. Baird, A. Hye, Nicholas J. Ashton, A. J. Nevado-Holgado, S. N. Anand, B. Liu, D. Newby, C. Bazenet, S. J. Kiddle, M. Ward, B. Newton, K. Desai, C. T. Hehir, M. Zanette, D. Galimberti, L. Parnetti, A. Lleo, S. Baker, V. A. Narayan, W. M. van der Flier, P. Scheltens, C. E. Teunissen, P. J. Visser, S. Lovestone
Frontiers in Aging Neuroscience - 2018-01-01 -
Update on biomarkers for amyloid pathology in Alzheimer's
disease
Nicholas J. Ashton, Michael Schöll, Kerstin Heurling, Eleni Gkanatsiou, Erik Portelius, Kina Höglund, Gunnar Brinkmalm, A Hye, Kaj Blennow, Henrik Zetterberg
Biomarkers in medicine - 2018-01-01