Silke Kern
Avd-/Sektionschef, bitr, inst
Sektionen för psykiatri ochProfessor/överläkare
Institutionen för neurovetenskap ochOm Silke Kern
Överläkare, forskargruppsledare. Biträdande sektionschef vid sektionen för psykiatri och neurokemi.
Akademisk grad: Docent
Forskningsintresse
Silke Kerns mål är att öka kunskapen om demens- och minnessjukdomar – från uppkomst till behandling.
- Biomarkörer i ryggvätska vid Alzheimers sjukdom
- Biomarkörer i hjärnavbildningar för diverse demenssjukdomar
- Riskfaktorer för insjuknande i demens
- Förekomsten av demens och förändringar över flera decennier
Pågående forskning
Dr. Kerns forskning fokuserar på att förstå tidiga markörer för olika demenssjukdomar såsom Alzheimers sjukdom, i ryggvätska och vid hjärnavbildning (brain MRI). Hon leder biomarkördelen i den välkända befolkningsstudien H70 och är forskargruppsledare för den nystartade kliniska H70-studien. Båda studierna är en del av Centrum för åldrande och hälsa (AGECAP) vid Göteborgs universitet.
Dr. Kern är också forskargruppsledare för European Prevention of Alzheimer’s Disease Study (EPAD) vid Minnesmottagningen, Sahlgrenska Universitetssjukhuset. Sedan många år har hon även forskat kring förekomsten av demens och olika riskfaktorer för insjuknande i demens (såsom livsstilsfaktorer, genetik etc).
Forskargrupp
Se även: H70-studierna i Göteborg
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Subtle Differences in Cognition in 70-Year-Olds with Elevated Cerebrospinal Fluid Neurofilament Light and Neurogranin: A H70 Cross-Sectional
Study
Maya Arvidsson Rådestig, Johan Skoog, Henrik Zetterberg, Tobias Skillbäck, Anna Zettergren, Therese Rydberg Sterner, Madeleine Mellqvist Fässberg, Simona Sacuiu, Margda Waern, Hanna Wetterberg, Kaj Blennow, Ingmar Skoog, Silke Kern
Journal of Alzheimers Disease - 2023 -
Reply to "Pathway for ascertaining the role of uric acid in neurodegenerative diseases," Roman
Youssef.
Mats Dehlin, Fatima Tahzeeb, Lennart T. H. Jacobsson, Silke Kern, Anna Zettergren, Kaj Blennow, Henrik Zetterberg, Lena Johansson, Ingmar Skoog
Alzheimer's & dementia (Amsterdam, Netherlands) - 2022 -
Representativeness in population-based studies of older adults: five waves of cross-sectional examinations in the Gothenburg H70 Birth Cohort
Study
Hanna Wetterberg, Lina Rydén, Felicia Ahlner, Hanna Falk Erhag, Pia Gudmundsson, Xinxin Guo, Erik Joas, Lena Johansson, Silke Kern, Madeleine Mellqvist Fässberg, Jenna Najar, Mats Ribbe, Therese Rydberg Sterner, Jessica Samuelsson, Simona Sacuiu, Robert Sigström, Johan Skoog, Margda Waern, Anna Zettergren, Ingmar Skoog
Bmj Open - 2022 -
Slowing gait speed precedes cognitive decline by several
years
Tobias Skillbäck, Kaj Blennow, Henrik Zetterberg, Johan Skoog, Lina Rydén, Hanna Wetterberg, Xinxin Guo, Simona Florentina Sacuiu, M. M. Mielke, Anna Zettergren, Ingmar Skoog, Silke Kern
Alzheimer's and Dementia - 2022 -
Unsupervised mobile app-based cognitive testing in a population-based study of older adults born
1944
Fredrik Öhman, D. Berron, K. V. Papp, Silke Kern, Johan Skoog, Timothy Hadarsson-Bodin, Anna Zettergren, Ingmar Skoog, Michael Schöll
Frontiers in Digital Health - 2022 -
Smartphone-based long-term delayed memory performance is associated with the Preclinical Alzheimer's Cognitive Composite and CSF levels of
β-amyloid.
Fredrik Öhman, David Berron, Johan Skoog, Timothy Hadarsson Bodin, Silke Kern, Anna Zettergren, Kathryn V Papp, Henrik Zetterberg, Kaj Blennow, Ingmar Skoog, Michael Schöll
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2022 -
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's
disease.
Douglas P Wightman, Iris E Jansen, Jeanne E Savage, Alexey A Shadrin, Shahram Bahrami, Dominic Holland, Arvid Rongve, Sigrid Børte, Bendik S Winsvold, Ole Kristian Drange, Amy E Martinsen, Anne Heidi Skogholt, Cristen Willer, Geir Bråthen, Ingunn Bosnes, Jonas Bille Nielsen, Lars G Fritsche, Laurent F Thomas, Linda M Pedersen, Maiken E Gabrielsen, Marianne Bakke Johnsen, Tore Wergeland Meisingset, Wei Zhou, Petroula Proitsi, Angela Hodges, Richard Dobson, Latha Velayudhan, Karl Heilbron, Adam Auton, Julia M Sealock, Lea K Davis, Nancy L Pedersen, Chandra A Reynolds, Ida K Karlsson, Sigurdur Magnusson, Hreinn Stefansson, Steinunn Thordardottir, Palmi V Jonsson, Jon Snaedal, Anna Zettergren, Ingmar Skoog, Silke Kern, Margda Waern, Henrik Zetterberg, Kaj Blennow, Eystein Stordal, Kristian Hveem, John-Anker Zwart, Lavinia Athanasiu, Per Selnes, Ingvild Saltvedt, Sigrid B Sando, Ingun Ulstein, Srdjan Djurovic, Tormod Fladby, Dag Aarsland, Geir Selbæk, Stephan Ripke, Kari Stefansson, Ole A Andreassen, Danielle Posthuma
Nature genetics - 2022 -
Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid
biomarkers.
Iris E Jansen, Sven J van der Lee, Duber Gomez-Fonseca, Itziar de Rojas, Maria Carolina Dalmasso, Benjamin Grenier-Boley, Anna Zettergren, Aniket Mishra, Muhammad Ali, Victor Andrade, Céline Bellenguez, Luca Kleineidam, Fahri Küçükali, Yun Ju Sung, Niccolo Tesí, Ellen M Vromen, Douglas P Wightman, Daniel Alcolea, Montserrat Alegret, Ignacio Alvarez, Philippe Amouyel, Lavinia Athanasiu, Shahram Bahrami, Henri Bailly, Olivia Belbin, Sverre Bergh, Lars Bertram, Geert Jan Biessels, Kaj Blennow, Rafael Blesa, Mercè Boada, Anne Boland, Katharina Buerger, Ángel Carracedo, Laura Cervera-Carles, Geneviève Chene, Jurgen A H R Claassen, Stephanie Debette, Jean-Francois Deleuze, Peter Paul de Deyn, Janine Diehl-Schmid, Srdjan Djurovic, Oriol Dols-Icardo, Carole Dufouil, Emmanuelle Duron, Emrah Düzel, Tormod Fladby, Juan Fortea, Lutz Frölich, Pablo García-González, Maria Garcia-Martinez, Ina Giegling, Oliver Goldhardt, Johan Gobom, Timo Grimmer, Annakaisa Haapasalo, Harald Hampel, Olivier Hanon, Lucrezia Hausner, Stefanie Heilmann-Heimbach, Seppo Helisalmi, Michael T Heneka, Isabel Hernández, Sanna-Kaisa Herukka, Henne Holstege, Jonas Jarholm, Silke Kern, Anne-Brita Knapskog, Anne M Koivisto, Johannes Kornhuber, Teemu Kuulasmaa, Carmen Lage, Christoph Laske, Ville Leinonen, Piotr Lewczuk, Alberto Lleó, Adolfo López de Munain, Sara Lopez-Garcia, Wolfgang Maier, Marta Marquié, Merel O Mol, Laura Montrreal, Fermin Moreno, Sonia Moreno-Grau, Gael Nicolas, Markus M Nöthen, Adelina Orellana, Lene Pålhaugen, Janne M Papma, Florence Pasquier, Robert Perneczky, Oliver Peters, Yolande A L Pijnenburg, Julius Popp, Danielle Posthuma, Ana Pozueta, Josef Priller, Raquel Puerta, Inés Quintela, Inez Ramakers, Eloy Rodriguez-Rodriguez, Dan Rujescu, Ingvild Saltvedt, Pascual Sanchez-Juan, Philip Scheltens, Norbert Scherbaum, Matthias Schmid, Anja Schneider, Geir Selbæk, Per Selnes, Alexey Shadrin, Ingmar Skoog, Hilkka Soininen, Lluís Tárraga, Stefan Teipel, Betty Tijms, Magda Tsolaki, Christine Van Broeckhoven, Jasper Van Dongen, John C van Swieten, Rik Vandenberghe, Jean-Sébastien Vidal, Pieter J Visser, Jonathan Vogelgsang, Margda Waern, Michael Wagner, Jens Wiltfang, Mandy M J Wittens, Henrik Zetterberg, Miren Zulaica, Cornelia M van Duijn, Maria Bjerke, Sebastiaan Engelborghs, Frank Jessen, Charlotte E Teunissen, Pau Pastor, Mikko Hiltunen, Martin Ingelsson, Ole A Andreassen, Jordi Clarimón, Kristel Sleegers, Agustín Ruiz, Alfredo Ramirez, Carlos Cruchaga, Jean-Charles Lambert, Wiesje van der Flier
Acta neuropathologica - 2022 -
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical
Spectrum.
Willemijn J Jansen, Olin Janssen, Betty M Tijms, Stephanie J B Vos, Rik Ossenkoppele, Pieter Jelle Visser, Dag Aarsland, Daniel Alcolea, Daniele Altomare, Christine von Arnim, Simone Baiardi, Ines Baldeiras, Henryk Barthel, Randall J Bateman, Bart Van Berckel, Alexa Pichet Binette, Kaj Blennow, Merce Boada, Henning Boecker, Michel Bottlaender, Anouk den Braber, David J Brooks, Mark A Van Buchem, Vincent Camus, Jose Manuel Carill, Jiri Cerman, Kewei Chen, Gaël Chételat, Elena Chipi, Ann D Cohen, Alisha Daniels, Marion Delarue, Mira Didic, Alexander Drzezga, Bruno Dubois, Marie Eckerström, Laura L Ekblad, Sebastiaan Engelborghs, Stéphane Epelbaum, Anne M Fagan, Yong Fan, Tormod Fladby, Adam S Fleisher, Wiesje M Van der Flier, Stefan Förster, Juan Fortea, Kristian Steen Frederiksen, Yvonne Freund-Levi, Lars Frings, Giovanni B Frisoni, Lutz Fröhlich, Tomasz Gabryelewicz, Hermann-Josef Gertz, Kiran Dip Gill, Olymbia Gkatzima, Estrella Gómez-Tortosa, Timo Grimmer, Eric Guedj, Christian G Habeck, Harald Hampel, Ron Handels, Oskar Hansson, Lucrezia Hausner, Sabine Hellwig, Michael T Heneka, Sanna-Kaisa Herukka, Helmut Hildebrandt, John Hodges, Jakub Hort, Chin-Chang Huang, Ane Juaristi Iriondo, Yoshiaki Itoh, Adrian Ivanoiu, William J Jagust, Frank Jessen, Peter Johannsen, Keith A Johnson, Ramesh Kandimalla, Elisabeth N Kapaki, Silke Kern, Lena Kilander, Aleksandra Klimkowicz-Mrowiec, William E Klunk, Norman Koglin, Johannes Kornhuber, Milica G Kramberger, Hung-Chou Kuo, Koen Van Laere, Susan M Landau, Brigitte Landeau, Dong Young Lee, Mony de Leon, Cristian E Leyton, Kun-Ju Lin, Alberto Lleó, Malin Löwenmark, Karine Madsen, Wolfgang Maier, Jan Marcusson, Marta Marquié, Pablo Martinez-Lage, Nancy Maserejian, Niklas Mattsson, Alexandre de Mendonça, Philipp T Meyer, Bruce L Miller, Shinobu Minatani, Mark A Mintun, Vincent C T Mok, Jose Luis Molinuevo, Silvia Daniela Morbelli, John C Morris, Barbara Mroczko, Duk L Na, Andrew Newberg, Flavio Nobili, Agneta Nordberg, Marcel G M Olde Rikkert, Catarina Resende de Oliveira, Pauline Olivieri, Adela Orellana, George Paraskevas, Piero Parchi, Matteo Pardini, Lucilla Parnetti, Oliver Peters, Judes Poirier, Julius Popp, Sudesh Prabhakar, Gil D Rabinovici, Inez H Ramakers, Lorena Rami, Eric M Reiman, Juha O Rinne, Karen M Rodrigue, Eloy Rodríguez-Rodriguez, Catherine M Roe, Pedro Rosa-Neto, Howard J Rosen, Uros Rot, Christopher C Rowe, Eckart Rüther, Agustín Ruiz, Osama Sabri, Jayant Sakhardande, Pascual Sánchez-Juan, Sigrid Botne Sando, Isabel Santana, Marie Sarazin, Philip Scheltens, Johannes Schröder, Per Selnes, Sang Won Seo, Dina Silva, Ingmar Skoog, Peter J Snyder, Hilkka Soininen, Marc Sollberger, Reisa A Sperling, Luisa Spiru, Yaakov Stern, Erik Stomrud, Akitoshi Takeda, Marc Teichmann, Charlotte E Teunissen, Louisa I Thompson, Jori Tomassen, Magda Tsolaki, Rik Vandenberghe, Marcel M Verbeek, Frans R J Verhey, Victor Villemagne, Sylvia Villeneuve, Jonathan Vogelgsang, Gunhild Waldemar, A. Wallin, Åsa K Wallin, Jens Wiltfang, David A Wolk, Tzu-Chen Yen, Marzena Zboch, Henrik Zetterberg
JAMA neurology - 2022 -
Association of Cerebrovascular and Alzheimer Disease Biomarkers With Cholinergic White Matter Degeneration in Cognitively Unimpaired
Individuals
N. Cedres, D. Ferreira, M. Nemy, A. Machado, J. B. Pereira, S. Shams, L. O. Wahlund, Anna Zettergren, O. Stepankova, L. Vyslouzilova, M. Eriksdotter, S. Teipel, M. J. Grothe, Kaj Blennow, Henrik Zetterberg, Michael Schöll, Silke Kern, Ingmar Skoog, E. Westman
Neurology - 2022 -
Brain charts for the human
lifespan
R. A. I. Bethlehem, J. Seidlitz, S. R. White, J. W. Vogel, K. M. Anderson, C. Adamson, S. Adler, G. S. Alexopoulos, E. Anagnostou, A. Areces-Gonzalez, D. E. Astle, B. Auyeung, M. Ayub, J. Bae, G. Ball, S. Baron-Cohen, R. Beare, S. A. Bedford, V. Benegal, F. Beyer, J. Blangero, M. B. Cabez, J. P. Boardman, M. Borzage, J. F. Bosch-Bayard, N. Bourke, V. D. Calhoun, M. M. Chakravarty, C. Chen, C. Chertavian, G. Chetelat, Y. S. Chong, J. H. Cole, A. Corvin, M. Costantino, E. Courchesne, F. Crivello, V. L. Cropley, J. Crosbie, N. Crossley, M. Delarue, R. Delorme, S. Desrivieres, G. A. Devenyi, M. A. Di Biase, R. Dolan, K. A. Donald, G. Donohoe, K. Dunlop, A. D. Edwards, J. T. Elison, C. T. Ellis, J. A. Elman, L. Eyler, D. A. Fair, E. Feczko, P. C. Fletcher, P. Fonagy, C. E. Franz, L. Galan-Garcia, A. Gholipour, J. Giedd, J. H. Gilmore, D. C. Glahn, I. M. Goodyer, P. E. Grant, N. A. Groenewold, F. M. Gunning, R. E. Gur, R. C. Gur, C. F. Hammill, O. Hansson, T. Hedden, A. Heinz, R. N. Henson, K. Heuer, J. Hoare, B. Holla, A. J. Holmes, R. Holt, H. Huang, K. Im, J. Ipser, C. R. Jack, A. P. Jackowski, T. Jia, K. A. Johnson, P. B. Jones, D. T. Jones, R. S. Kahn, H. Karlsson, L. Karlsson, R. Kawashima, E. A. Kelley, Silke Kern, K. W. Kim, M. G. Kitzbichler, W. S. Kremen, F. Lalonde, B. Landeau, S. Lee, J. Lerch, J. D. Lewis, J. Li, W. Liao, C. Liston, M. V. Lombardo, J. Lv, C. Lynch, T. T. Mallard, M. Marcelis, R. D. Markello, S. R. Mathias, B. Mazoyer, P. McGuire, M. J. Meaney, A. Mechelli, N. Medic, B. Misic, S. E. Morgan, D. Mothersill, J. Nigg, M. Q. W. Ong, C. Ortinau, R. Ossenkoppele, M. Ouyang, L. Palaniyappan, L. Paly, P. M. Pan, C. Pantelis, M. M. Park, T. Paus, Z. Pausova, D. Paz-Linares, A. P. Binette, K. Pierce, X. Qian, J. Qiu, A. Qiu, A. Raznahan, T. Rittman, A. Rodrigue, C. K. Rollins, R. Romero-Garcia, L. Ronan, M. D. Rosenberg, D. H. Rowitch, G. A. Salum, T. D. Satterthwaite, H. L. Schaare, R. J. Schachar, A. P. Schultz, G. Schumann, M. Scholl, D. Sharp, R. T. Shinohara, Ingmar Skoog, C. D. Smyser, R. A. Sperling, D. J. Stein, A. Stolicyn, J. Suckling, G. Sullivan, Y. Taki, B. Thyreau, R. Toro, N. Traut, K. A. Tsvetanov, N. B. Turk-Browne, J. J. Tuulari, C. Tzourio, E. Vachon-Presseau, M. J. Valdes-Sosa, P. A. Valdes-Sosa, S. L. Valk, T. van Amelsvoort, S. N. Vandekar, L. Vasung, L. W. Victoria, S. Villeneuve, A. Villringer, P. E. Vertes, K. Wagstyl, Y. S. Wang, S. K. Warfield, V. Warrier, E. Westman, M. L. Westwater, H. C. Whalley, A. V. Witte, N. Yang, B. Yeo, H. Yun, A. Zalesky, H. J. Zar, A. Zettergren, J. H. Zhou, H. Ziauddeen, A. Zugman, X. N. Zuo, E. T. Bullmore, A. F. Alexander-Bloch, Brain R, Aibl, Aibl,
Nature - 2022 -
The protective gene dose effect of the APOE epsilon 2 allele on gray matter volume in cognitively unimpaired
individuals
G. Salvado, D. Ferreira, G. Operto, I. Cumplido-Mayoral, E. M. Arenaza-Urquijo, R. Cacciaglia, C. Falcon, N. Vilor-Tejedor, C. Minguillon, C. Groot, W. M. van der Flier, F. Barkhof, P. Scheltens, R. Ossenkoppele, Silke Kern, Anna Zettergren, Ingmar Skoog, J. Hort, E. Stomrud, D. van Westen, O. Hansson, J. L. Molinuevo, L. O. Wahlund, E. Westman, J. D. Gispert
Alzheimers & Dementia - 2022 -
Plasma and CSF NfL are differentially associated with biomarker evidence of neurodegeneration in a community-based sample of
70-year-olds
Anna Dittrich, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Joel Simrén, Fiona Geiger, Anna Zettergren, S. Shams, A. Machado, E. Westman, Michael Schöll, Ingmar Skoog, Silke Kern
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring - 2022 -
Interactions between dietary patterns and genetic factors in relation to incident dementia among
70-year-olds
Jessica Samuelsson, Jenna Najar, O. Wallengren, Silke Kern, Hanna Wetterberg, Madeleine Mellqvist Fässberg, Henrik Zetterberg, Kaj Blennow, Lauren Lissner, E. Rothenberg, Ingmar Skoog, Anna Zettergren
European Journal of Nutrition - 2022 -
Cerebrospinal Fluid Biomarkers, Brain Structural and Cognitive Performances Between Normotensive and Hypertensive Controlled, Uncontrolled and Untreated 70-Year-Old
Adults
A. Badji, J. B. Pereira, S. Shams, Johan Skoog, A. Marseglia, K. Poulakis, Lina Rydén, Kaj Blennow, Henrik Zetterberg, Silke Kern, Anna Zettergren, L. O. Wahlund, H. Girouard, Ingmar Skoog, E. Westman
Frontiers in Aging Neuroscience - 2022 -
Comparison of Two-Dimensional- and Three-Dimensional-Based U-Net Architectures for Brain Tissue Classification in One-Dimensional Brain
CT.
Meera Srikrishna, Rolf A. Heckemann, Joana B Pereira, Giovanni Volpe, Anna Zettergren, Silke Kern, Eric Westman, Ingmar Skoog, Michael Schöll
Frontiers in computational neuroscience - 2021 -
A non-APOE polygenic risk score for Alzheimer's disease is associated with CSF neurofilament light in a representative sample of cognitively unimpaired
70-year-olds.
Ingmar Skoog, Silke Kern, Jenna Najar, Rita Guerreiro, Jose Bras, Margda Waern, Henrik Zetterberg, Kaj Blennow, Anna Zettergren
The journals of gerontology. Series A, Biological sciences and medical sciences - 2021 -
Sex differences in CSF biomarkers for neurodegeneration and blood-brain barrier
integrity.
Tobias Skillbäck, Kaj Blennow, Henrik Zetterberg, Sara Shams, Alejandra Machado, Joana Pereira, Olof Lindberg, Michelle M Mielke, Anna Zettergren, Lina Rydén, Eric Westman, Lars-Olof Wahlund, Ingmar Skoog, Silke Kern
Alzheimer's & dementia - 2021 -
Association of CSF proteins with tau and amyloid β levels in asymptomatic
70-year-olds.
Julia Remnestål, Sofia Bergström, Jennie Olofsson, Evelina Sjöstedt, Mathias Uhlén, Kaj Blennow, Henrik Zetterberg, Anna Zettergren, Silke Kern, Ingmar Skoog, Peter Nilsson, Anna Månberg
Alzheimer's research & therapy - 2021 -
Cognitive Performance and Cerebrospinal Fluid Markers in Preclinical Alzheimer's Disease: Results from the Gothenburg H70 Birth Cohort
Studies.
Maya Arvidsson Rådestig, Johan Skoog, Henrik Zetterberg, Jürgen Kern, Anna Zettergren, Simona Sacuiu, Margda Waern, Hanna Wetterberg, Kaj Blennow, Ingmar Skoog, Silke Kern
Journal of Alzheimer's disease : JAD - 2021 -
Comparison of CSF neurofilament light chain, neurogranin, and tau to MRI
markers
M. M. Mielke, S. A. Przybelski, T. G. Lesnick, Silke Kern, Henrik Zetterberg, Kaj Blennow, D. S. Knopman, J. Graff-Radford, R. C. Petersen, C. R. Jack, P. Vemuri
Alzheimers & Dementia - 2021 -
Effects of amyloid pathology and the APOE epsilon 4 allele on the association between cerebrospinal fluid A beta 38 and A beta 40 and brain morphology in cognitively normal
70-years-olds
O. Lindberg, Silke Kern, Johan Skoog, A. Machado, J. B. Pereira, Simona Florentina Sacuiu, L. O. Wahlund, Kaj Blennow, Henrik Zetterberg, Anna Zettergren, E. Westman, Ingmar Skoog
Neurobiology of Aging - 2021 -
Association between serum urate and CSF markers of Alzheimer's disease pathology in a population-based sample of
70-year-olds
Fatima Tahzeeb, Lennart T. H. Jacobsson, Silke Kern, Anna Zettergren, Kaj Blennow, Henrik Zetterberg, Lena Johansson, Mats Dehlin, Ingmar Skoog
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring - 2021 -
Metabolic Syndrome Is Associated With Poor Cognition: A Population-Based Study of 70-Year-Old Adults Without
Dementia.
Anna Marseglia, Alexander Darin-Mattsson, Johan Skoog, Lina Rydén, Timothy Hadarsson-Bodin, Silke Kern, Therese Rydberg Sterner, Ying Shang, Anna Zettergren, Eric Westman, Ingmar Skoog
The journals of gerontology. Series A, Biological sciences and medical sciences - 2021 -
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's
disease.
Douglas P Wightman, Iris E Jansen, Jeanne E Savage, Alexey A Shadrin, Shahram Bahrami, Dominic Holland, Arvid Rongve, Sigrid Børte, Bendik S Winsvold, Ole Kristian Drange, Amy E Martinsen, Anne Heidi Skogholt, Cristen Willer, Geir Bråthen, Ingunn Bosnes, Jonas Bille Nielsen, Lars G Fritsche, Laurent F Thomas, Linda M Pedersen, Maiken E Gabrielsen, Marianne Bakke Johnsen, Tore Wergeland Meisingset, Wei Zhou, Petroula Proitsi, Angela Hodges, Richard Dobson, Latha Velayudhan, Karl Heilbron, Adam Auton, Julia M Sealock, Lea K Davis, Nancy L Pedersen, Chandra A Reynolds, Ida K Karlsson, Sigurdur Magnusson, Hreinn Stefansson, Steinunn Thordardottir, Palmi V Jonsson, Jon Snaedal, Anna Zettergren, Ingmar Skoog, Silke Kern, Margda Waern, Henrik Zetterberg, Kaj Blennow, Eystein Stordal, Kristian Hveem, John-Anker Zwart, Lavinia Athanasiu, Per Selnes, Ingvild Saltvedt, Sigrid B Sando, Ingun Ulstein, Srdjan Djurovic, Tormod Fladby, Dag Aarsland, Geir Selbæk, Stephan Ripke, Kari Stefansson, Ole A Andreassen, Danielle Posthuma
Nature genetics - 2021 -
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's
disease
D. P. Wightman, I. E. Jansen, J. E. Savage, A. A. Shadrin, S. Bahrami, D. Holland, A. Rongve, S. Borte, B. S. Winsvold, O. K. Drange, A. E. Martinsen, A. H. Skogholt, C. Willer, G. Brathen, I. Bosnes, J. B. Nielsen, L. G. Fritsche, L. F. Thomas, L. M. Pedersen, M. E. Gabrielsen, M. B. Johnsen, T. W. Meisingset, W. Zhou, P. Proitsi, A. Hodges, R. Dobson, L. Velayudhan, J. M. Sealock, L. K. Davis, N. L. Pedersen, C. A. Reynolds, I. K. Karlsson, S. Magnusson, H. Stefansson, S. Thordardottir, P. V. Jonsson, J. Snaedal, Anna Zettergren, Ingmar Skoog, Silke Kern, Margda Waern, Henrik Zetterberg, Kaj Blennow, E. Stordal, K. Hveem, J. A. Zwart, L. Athanasiu, P. Selnes, I. Saltvedt, S. B. Sando, I. Ulstein, S. Djurovic, T. Fladby, D. Aarsland, G. Selbaek, S. Ripke, K. Stefansson, O. A. Andreassen, D. Posthuma, Team andMe Res
Nature Genetics - 2021 -
Reproductive period and preclinical cerebrospinal fluid markers for Alzheimer disease: a 25-year
study
Jenna Najar, Tore Hällström, Anna Zettergren, Lena Johansson, Erik Joas, Madeleine Mellqvist Fässberg, Henrik Zetterberg, Kaj Blennow, Silke Kern, Ingmar Skoog
Menopause-the Journal of the North American Menopause Society - 2021 -
Deep learning from MRI-derived labels enables automatic brain tissue classification on human brain
CT.
Meera Srikrishna, Joana B Pereira, Rolf A. Heckemann, Giovanni Volpe, Danielle van Westen, Anna Zettergren, Silke Kern, Lars-Olof Wahlund, Eric Westman, Ingmar Skoog, Michael Schöll
NeuroImage - 2021 -
Atrial Fibrillation, Stroke, and Silent Cerebrovascular Disease A Population-based MRI
Study
Lina Rydén, Simona Sacuiu, Hanna Wetterberg, Jenna Najar, Xinxin Guo, Silke Kern, Anna Zettergren, S. Shams, J. B. Pereira, L. O. Wahlund, E. Westman, Ingmar Skoog
Neurology - 2021 -
Sex Difference in the Relation Between Marital Status and Dementia Risk in Two Population-Based
Cohorts
Jenna Najar, J. A. Aakre, M. Vassilaki, Hanna Wetterberg, Lina Rydén, Anna Zettergren, Ingmar Skoog, C. R. Jack, D. S. Knopman, R. C. Petersen, Silke Kern, M. M. Mielke
Journal of Alzheimers Disease - 2021 -
Time trends in the relation between blood pressure and dementia in
85-year-olds
Mats Ribbe, Silke Kern, Hanna Wetterberg, Lina Rydén, Anna Zettergren, Xinxin Guo, Ingmar Skoog
Journal of hypertension - 2021 -
Common variants in Alzheimer’s disease and risk stratification by polygenic risk
scores
I. de Rojas, S. Moreno-Grau, N. Tesi, B. Grenier-Boley, V. Andrade, I. E. Jansen, N. L. Pedersen, N. Stringa, Anna Zettergren, I. Hernández, L. Montrreal, C. Antúnez, A. Antonell, R. M. Tankard, J. C. Bis, R. Sims, C. Bellenguez, I. Quintela, A. González-Perez, M. Calero, E. Franco-Macías, J. Macías, R. Blesa, L. Cervera-Carles, M. Menéndez-González, A. Frank-García, J. L. Royo, F. Moreno, R. Huerto Vilas, M. Baquero, M. Diez-Fairen, C. Lage, S. García-Madrona, P. García-González, E. Alarcón-Martín, S. Valero, O. Sotolongo-Grau, A. Ullgren, A. C. Naj, A. W. Lemstra, A. Benaque, A. Pérez-Cordón, A. Benussi, A. Rábano, A. Padovani, A. Squassina, A. de Mendonça, A. Arias Pastor, A. A. L. Kok, A. Meggy, A. B. Pastor, A. Espinosa, A. Corma-Gómez, A. Martín Montes, Á Sanabria, A. L. DeStefano, A. Schneider, A. Haapasalo, A. Kinhult Ståhlbom, A. Tybjærg-Hansen, A. M. Hartmann, A. Spottke, A. Corbatón-Anchuelo, A. Rongve, B. Borroni, B. Arosio, B. Nacmias, B. G. Nordestgaard, B. W. Kunkle, C. Charbonnier, C. Abdelnour, C. Masullo, C. Martínez Rodríguez, C. Muñoz-Fernandez, C. Dufouil, C. Graff, C. B. Ferreira, C. Chillotti, C. A. Reynolds, C. Fenoglio, C. Van Broeckhoven, C. Clark, C. Pisanu, C. L. Satizabal, C. Holmes, D. Buiza-Rueda, D. Aarsland, D. Rujescu, D. Alcolea, D. Galimberti, D. Wallon, D. Seripa, E. Grünblatt, E. Dardiotis, E. Düzel, E. Scarpini, E. Conti, E. Rubino, E. Gelpi, E. Rodriguez-Rodriguez, E. Duron, E. Boerwinkle, E. Ferri, F. Tagliavini, F. Küçükali, F. Pasquier, F. Sanchez-Garcia, F. Mangialasche, F. Jessen, G. Nicolas, G. Selbæk, G. Ortega, G. Chêne, G. Hadjigeorgiou, G. Rossi, G. Spalletta, G. Giaccone, G. Grande, G. Binetti, G. Papenberg, H. Hampel, H. Bailly, Henrik Zetterberg, H. Soininen, I. K. Karlsson, I. Alvarez, I. Appollonio, I. Giegling, Ingmar Skoog, I. Saltvedt, I. Rainero, I. Rosas Allende, J. Hort, J. Diehl-Schmid, J. Van Dongen, J. S. Vidal, J. Lehtisalo, J. Wiltfang, J. Q. Thomassen, J. Kornhuber, J. L. Haines, J. Vogelgsang, J. A. Pineda, J. Fortea, J. Popp, J. Deckert, K. Buerger, K. Morgan, K. Fließbach, K. Sleegers, L. Molina-Porcel, L. Kilander, L. Weinhold, L. A. Farrer, L. S. Wang, L. Kleineidam, L. Farotti, L. Parnetti, L. Tremolizzo, L. Hausner, L. Benussi, L. Froelich, M. A. Ikram, M. C. Deniz-Naranjo, M. Tsolaki, M. Rosende-Roca, M. Löwenmark, M. Hulsman, M. Spallazzi, M. A. Pericak-Vance, M. Esiri, M. Bernal Sánchez-Arjona, M. C. Dalmasso, M. T. Martínez-Larrad, M. Arcaro, M. M. Nöthen, M. Fernández-Fuertes, M. Dichgans, M. Ingelsson, M. J. Herrmann, M. Scherer, M. Vyhnalek, M. H. Kosmidis, M. Yannakoulia, M. Schmid, M. Ewers, M. T. Heneka, M. Wagner, M. Scamosci, M. Kivipelto, M. Hiltunen, M. Zulaica, M. Alegret, M. Fornage, N. Roberto, N. M. van Schoor, Nazib Seidu, N. Banaj, N. J. Armstrong, N. Scarmeas, N. Scherbaum, O. Goldhardt, O. Hanon, O. Peters, O. A. Skrobot, O. Quenez, O. Lerch, P. Bossù, P. Caffarra, P. Dionigi Rossi, P. Sakka, P. Hoffmann, P. A. Holmans, P. Fischer, P. Riederer, Q. Yang, R. Marshall, R. N. Kalaria, R. Mayeux, R. Vandenberghe, R. Cecchetti, R. Ghidoni, R. Frikke-Schmidt, S. Sorbi, S. Hägg, S. Engelborghs, S. Helisalmi, S. Botne Sando, Silke Kern, S. Archetti, S. Boschi, S. Fostinelli, S. Gil, S. Mendoza, S. Mead, S. Ciccone, S. Djurovic, S. Heilmann-Heimbach, S. Riedel-Heller, T. Kuulasmaa, T. del Ser, T. Lebouvier, T. Polak, T. Ngandu, T. Grimmer, V. Bessi, V. Escott-Price, V. Giedraitis, V. Deramecourt, W. Maier, X. Jian, Y. A. L. Pijnenburg, A. D. Smith, A. Saenz, A. Bizzarro, A. Lauria, A. Vacca, A. Solomon, A. Anastasiou, A. Richardson, A. Boland, A. Koivisto, A. Daniele, A. Greco, A. Marianthi, B. McGuinness, B. Fin, C. Ferrari, C. Custodero, C. Ferrarese, C. Ingino, C. Mangone, C. Reyes Toso, C. Martínez, C. Cuesta, C. Muchnik, C. Joachim, C. Ortiz, C. Besse, C. Johansson, C. P. Zoia, C. Laske, C. Anastasiou, D. L. Palacio, D. G. Politis, D. Janowitz, D. Craig, D. M. Mann, D. Neary, D. Jürgen, D. Daian, D. Belezhanska, E. Kohler, E. M. Castaño, E. Koutsouraki, E. Chipi, E. De Roeck, E. Costantini, E. R. L. C. Vardy, F. Piras, F. Roveta, F. Piras, F. A. Prestia, F. Assogna, F. Salani, G. Sala, G. Lacidogna, G. Novack, G. Wilcock, H. Thonberg, H. Kölsch, H. Weber, H. Boecker, I. Etchepareborda, I. Piaceri, J. Tuomilehto, J. Lindström, J. Laczo, J. Johnston, J. F. Deleuze, J. Harris, J. M. Schott, J. Priller, J. I. Bacha, J. Snowden, J. Lisso, K. Y. Mihova, L. Traykov, L. Morelli, L. I. Brusco, M. Rainer, M. Takalo, M. Bjerke, M. Del Zompo, M. Serpente, M. Sanchez Abalos, M. Rios, M. Peltonen, M. J. Herrman, M. H. Kosmidis, M. Kohler, M. Rojo, M. Jones, M. Orsini, N. Medel, N. Olivar, N. C. Fox, N. Salvadori, N. M. Hooper, P. Galeano, P. Solis, P. Bastiani, P. Mecocci, P. Passmore, R. Heun, R. Antikainen, R. Olaso, R. Perneczky, S. Germani, S. López-García, S. Love, S. Mehrabian, S. Bagnoli, S. Kochen, S. Andreoni, S. Teipel, S. Todd, S. Pickering-Brown, T. Natunen, T. Tegos, T. Laatikainen, T. Strandberg, T. M. Polvikoski, V. Matoska, V. Ciullo, V. Cores, V. Solfrizzi, V. Lisetti, Z. Sevillano, C. Abdelnour, N. Aguilera, E. Alarcon, M. Alegret, A. Benaque, M. Boada, M. Buendia, P. Cañabate, A. Carracedo, A. Corbatón-Anchuelo, I. de Rojas, S. Diego, A. Espinosa, A. Gailhajenet, P. García-González, S. Gil, M. Guitart, A. González-Pérez, I. Hernández, M. Ibarria, A. Lafuente, J. Macias, O. Maroñas, E. Martín, M. T. Martínez, M. Marquié, A. Mauleón, L. Montrreal, S. Moreno-Grau, M. Moreno, A. Orellana, G. Ortega, A. Pancho, E. Pelejá, A. Pérez-Cordon, J. A. Pineda, S. Preckler, I. Quintela, L. M. Real, M. Rosende-Roca, A. Ruiz, M. E. Sáez, A. Sanabria, M. Serrano-Rios, O. Sotolongo-Grau, L. Tárraga, S. Valero, L. Vargas, A. D. Adarmes-Gómez, E. Alarcón-Martín, M. D. Alonso, I. Álvarez, V. Álvarez, G. Amer-Ferrer, M. Antequera, C. Antúnez, M. Baquero, M. Bernal, R. Blesa, M. Boada, D. Buiza-Rueda, M. J. Bullido, J. A. Burguera, M. Calero, F. Carrillo, M. Carrión-Claro, M. J. Casajeros, J. Clarimón, J. M. Cruz-Gamero, M. M. de Pancorbo, I. de Rojas, T. del Ser, M. Diez-Fairen, R. Escuela, L. Garrote-Espina, J. Fortea, E. Franco-Macías, A. Frank-García, J. M. García-Alberca, S. Garcia Madrona, G. Garcia-Ribas, P. Gómez-Garre, I. Hernández, S. Hevilla, S. Jesús, M. A. Labrador Espinosa, C. Lage, A. Legaz, A. Lleó, A. Lopez de Munain, S. López-García, D. Macias-García, S. Manzanares, M. Marín, J. Marín-Muñoz, T. Marín, M. Marquié, A. Martín Montes, B. Martínez, C. Martínez, V. Martínez, P. Martínez-Lage Álvarez, M. Medina, M. Mendioroz Iriarte, M. Menéndez-González, P. Mir, J. L. Molinuevo, P. Pastor, J. Pérez Tur, T. Periñán-Tocino, R. Pineda-Sanchez, G. Piñol-Ripoll, A. Rábano, D. Real de Asúa, S. Rodrigo, E. Rodríguez-Rodríguez, J. L. Royo, A. Ruiz, R. Sanchez del Valle Díaz, P. Sánchez-Juan, I. Sastre, S. Valero, M. P. Vicente, R. Vigo-Ortega, L. Vivancos, C. Macleod, C. McCracken, C. Brayne, C. Bresner, D. Grozeva, E. Bellou, E. W. Sommerville, F. Matthews, G. Leonenko, G. Menzies, G. Windle, J. Harwood, J. Phillips, K. Bennett, L. Luckuck, L. Clare, R. Woods, S. Saad, V. Burholt, I. E. Jansen, A. Rongve, P. G. Kehoe, G. Garcia-Ribas, P. Sánchez-Juan, P. Pastor, J. Pérez-Tur, G. Piñol-Ripoll, A. Lopez de Munain, J. M. García-Alberca, M. J. Bullido, V. Álvarez, A. Lleó, L. M. Real, P. Mir, M. Medina, P. Scheltens, H. Holstege, M. Marquié, M. E. Sáez, Á Carracedo, P. Amouyel, G. D. Schellenberg, J. Williams, S. Seshadri, C. M. van Duijn, K. A. Mather, R. Sánchez-Valle, M. Serrano-Ríos, A. Orellana, L. Tárraga, Kaj Blennow, M. Huisman, O. A. Andreassen, D. Posthuma, J. Clarimón, M. Boada, W. M. van der Flier, A. Ramirez, J. C. Lambert, S. J. van der Lee, A. Ruiz
Nature Communications - 2021 -
Dementia remains the major predictor of death among octogenarians. A study of two population cohorts of 85-year-olds examined 22 years
apart
Hanna Wetterberg, Jenna Najar, Lina Rydén, Mats Ribbe, Therese Rydberg Sterner, Anna Zettergren, Xinxin Guo, Hanna Falk Erhag, Simona Sacuiu, Silke Kern, Ingmar Skoog
European Journal of Epidemiology - 2021 -
A Western-style dietary pattern is associated with cerebrospinal fluid biomarker levels for preclinical Alzheimer's disease-A population-based cross-sectional study among
70-year-olds
Jessica Samuelsson, Silke Kern, Henrik Zetterberg, Kaj Blennow, Elisabeth Rothenberg, Ola Wallengren, Ingmar Skoog, Anna Zettergren
Alzheimer's & dementia (New York, N. Y.) - 2021 -
Effects of amyloid pathology and the APOE ε4 allele on the association between cerebrospinal fluid Aβ38 and Aβ40 and brain morphology in cognitively normal
70-years-olds.
Olof Lindberg, Silke Kern, Alejandra Machado, Joana B Pereira, Simona F Sacuiu, Lars-Olof Wahlund, Kaj Blennow, Henrik Zetterberg, Anna Zettergren, Eric Westman, Ingmar Skoog
Neurobiology of aging - 2021 -
Polygenic risk scores for Alzheimer's disease are related to dementia risk in APOE ɛ4
negatives.
Jenna Najar, Sven J van der Lee, Erik Joas, Hanna Wetterberg, John Hardy, Rita Guerreiro, Jose Bras, Margda Waern, Silke Kern, Henrik Zetterberg, Kaj Blennow, Ingmar Skoog, Anna Zettergren
Alzheimer's & dementia (Amsterdam, Netherlands) - 2021 -
Depression in relation to sex and gender expression among Swedish septuagenarians-Results from the H70
study
Therese Rydberg Sterner, Pia Gudmundsson, Hanna Falk, Nazib Seidu, Felicia Ahlner, Hanna Wetterberg, Lina Rydén, Robert Sigström, Svante Östling, Anna Zettergren, Silke Kern, Margda Waern, Ingmar Skoog
Plos One - 2020 -
Reproductive period and dementia: A 44-year longitudinal population study of Swedish
women
Jenna Najar, Svante Östling, Margda Waern, Anna Zettergren, Silke Kern, Hanna Wetterberg, Tore Hällström, Ingmar Skoog
Alzheimers & Dementia - 2020 -
Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts
Consortium.
Frank J Wolters, Lori B Chibnik, Reem Waziry, Roy Anderson, Claudine Berr, Alexa Beiser, Joshua C Bis, Deborah Blacker, Daniel Bos, Carol Brayne, Jean-François Dartigues, Sirwan K L Darweesh, Kendra L Davis-Plourde, Frank de Wolf, Stephanie Debette, Carole Dufouil, Myriam Fornage, Jaap Goudsmit, Leslie Grasset, Vilmundur Gudnason, Christoforos Hadjichrysanthou, Catherine Helmer, M Arfan Ikram, M Kamran Ikram, Erik Joas, Silke Kern, Lewis H Kuller, Lenore Launer, Oscar L Lopez, Fiona E Matthews, Kevin McRae-McKee, Osorio Meirelles, Thomas H Mosley, Matthew P Pase, Bruce M Psaty, Claudia L Satizabal, Sudha Seshadri, Ingmar Skoog, Blossom C M Stephan, Hanna Wetterberg, Mei Mei Wong, Anna Zettergren, Albert Hofman
Neurology - 2020 -
Epidemiology of suicidal feelings in an ageing Swedish population: From old to very old age in the Gothenburg H70 Birth Cohort
Studies
Madeleine Mellqvist Fässberg, Barbara Vanaelst, Mattias Jonson, Therese Rydberg Sterner, Felicia Ahlner, Hanna Wetterberg, Lina Rydén, Silke Kern, Robert Sigström, Anna Zettergren, Ingmar Skoog, Margda Waern
Epidemiology and Psychiatric Sciences - 2020 -
Predicting Fazekas scores from automatic segmentations of white matter signal
abnormalities
N. Cedres, D. Ferreira, A. Machado, S. Shams, Simona Sacuiu, Margda Waern, L. O. Wahlund, Anna Zettergren, Silke Kern, Ingmar Skoog, E. Westman
Aging-Us - 2020 -
Association of IL1RAP-related genetic variation with cerebrospinal fluid concentration of Alzheimer-associated tau
protein
Anna Zettergren, Kina Höglund, Silke Kern, Valgeir Thorvaldsson, Johan Skoog, O. Hansson, N. Andreasen, N. Bogdanovic, Kaj Blennow, Ingmar Skoog, Henrik Zetterberg
Scientific Reports - 2019 -
Plasma and CSF neurofilament light Relation to longitudinal neuroimaging and cognitive
measures
M. M. Mielke, J. A. Syrjanen, Kaj Blennow, Henrik Zetterberg, P. Vemuri, Ingmar Skoog, M. M. Machulda, W. K. Kremers, D. S. Knopman, C. Jack, R. C. Petersen, Silke Kern
Neurology - 2019 -
Comparison of variables associated with cerebrospinal fluid neurofilament, total-tau, and
neurogranin.
Michelle M Mielke, Jeremy A Syrjanen, Kaj Blennow, Henrik Zetterberg, Ingmar Skoog, Prashanthi Vemuri, Mary M Machulda, Jonathan Graff-Radford, David S Knopman, Clifford R Jack, Ronald C Petersen, Silke Kern
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2019 -
Association of Cerebrospinal Fluid Neurofilament Light Protein With Risk of Mild Cognitive Impairment Among Individuals Without Cognitive
Impairment.
Silke Kern, Jeremy A Syrjanen, Kaj Blennow, Ingmar Skoog, Henrik Zetterberg, Margda Waern, Clinton E Hagen, Argonde C van Harten, David S Knopman, Clifford R Jack, Ronald C Petersen, Michelle M Mielke
JAMA neurology - 2019 -
Amyloid β42 and Total Tau Levels in Cerebrospinal Fluid Associate with Survival in an 85-Year-Old Population-Based Cohort Followed until
Death
Mats Ribbe, Anne Börjesson-Hanson, Silke Kern, Svante Östling, Henrik Zetterberg, Kaj Blennow, Ingmar Skoog
Dementia and Geriatric Cognitive Disorders - 2019 -
Agreement between self-reports, proxy-reports and the National Patient Register regarding diagnoses of cardiovascular disorders and diabetes mellitus in a population-based sample of
80-year-olds
Lina Rydén, Robert Sigström, Johan Nilsson, Valter Sundh, Hanna Falk, Silke Kern, Margda Waern, Svante Östling, Katarina Wilhelmson, Ingmar Skoog
Age and Ageing - 2019 -
Atrial fibrillation increases the risk of dementia amongst older adults even in the absence of
stroke
Lina Rydén, Anna Zettergren, Nazib Seidu, Xinxin Guo, Silke Kern, Kaj Blennow, Henrik Zetterberg, Simona Sacuiu, Ingmar Skoog
Journal of Internal Medicine - 2019 -
Longstanding psychological stress in relation to biomarkers of neuronal dysfunction in cerebrospinal fluid: a 25-year follow-up study in
women
Lena Johansson, Simona Sacuiu, Silke Kern, Xinxin Guo, Henrik Zetterberg, Kaj Blennow, Anna Zettergren, Ingmar Skoog
Neurobiology of Aging - 2019 -
Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease
progression
S. De, D. R. Whiten, F. S. Ruggeri, C. Hughes, M. Rodrigues, D. I. Sideris, C. G. Taylor, F. A. Aprile, S. Muyldermans, T. P. J. Knowles, M. Vendruscolo, C. Bryant, Kaj Blennow, Ingmar Skoog, Silke Kern, Henrik Zetterberg, D. Klenerman
Acta Neuropathologica Communications - 2019 -
Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE
genotype
L. Vermunt, S. A. M. Sikkes, A. van den Hout, R. Handels, I. Bos, W. M. van der Flier, Silke Kern, P. J. Ousset, P. Maruff, Ingmar Skoog, F. R. J. Verhey, Y. Freund-Levi, M. Tsolaki, A. K. Wallin, M. O. Rikkert, H. Soininen, L. Spiru, Henrik Zetterberg, Kaj Blennow, P. Scheltens, G. Muniz-Terrera, P. J. Visser, B. Vellas, E. Reynish, P. J. Ousset, S. Andrieu, A. Burns, F. Pasquier, G. Frisoni, E. Salmon, J. P. Michel, D. S. Zekry, M. Boada, J. F. Dartigues, M. G. M. Olde-Rikkert, A. S. Rigaud, B. Winblad, A. Malick, A. Sinclair, L. Frolich, P. Scheltens, C. Ribera, J. Touchon, P. Robert, A. Salva, G. Waldemar, R. Bullock, M. Tsolaki, G. Rodriguez, L. Spiru, R. W. Jones, G. Stiens, G. Stoppe, M. E. Jonhagen, A. Cherubini, P. M. Lage, T. Gomezisla, V. Camus, E. Aguera-Morales, F. Lopez, S. Savy, C. Cantet, N. Coley
Alzheimers & Dementia - 2019 -
Urate and risk of Alzheimer's disease and vascular dementia: A population-based
study
Lieke Scheepers, Lennart T. H. Jacobsson, Silke Kern, Lena Johansson, Mats Dehlin, Ingmar Skoog
Alzheimers & Dementia - 2019 -
Depression and neuroticism decrease among women but not among men between 1976-2016 in Swedish
septuagenarians
Therese Rydberg Sterner, Pia Gudmundsson, Robert Sigström, Felicia Ahlner, Nazib Seidu, Anna Zettergren, Silke Kern, Svante Östling, Margda Waern, Ingmar Skoog
Acta Psychiatrica Scandinavica - 2019 -
The Gothenburg H70 Birth cohort study 2014-16: design, methods and study
population.
Therese Rydberg Sterner, Felicia Ahlner, Kaj Blennow, Synneve Dahlin-Ivanoff, Hanna Falk, Lena Havstam Johansson, Maria Hoff, Mathias Holm, Helena M Hörder, Tina Jacobsson, Boo Johansson, Lena Johansson, Jürgen Kern, Silke Kern, Alejandra Machado, Madeleine Mellqvist Fässberg, Johan Nilsson, Mats Ribbe, Elisabeth Rothenberg, Lina Rydén, André M. Sadeghi, Simona Sacuiu, Jessica Samuelsson, Robert Sigström, Johan Skoog, Valgeir Thorvaldsson, Margda Waern, Eric Westman, Hanna Wetterberg, Henrik Zetterberg, Madeleine Zetterberg, Anna Zettergren, Svante Östling, Ingmar Skoog
European journal of epidemiology - 2019 -
Cognitive and physical activity and dementia A 44-year longitudinal population study of
women
Jenna Najar, Svante Östling, Pia Gudmundsson, Valter Sundh, Lena Johansson, Silke Kern, Xinxin Guo, Tore Hällström, Ingmar Skoog
Neurology - 2019 -
Increased Alcohol Consumption Among Swedish 70-Year-Olds 1976 to 2016: Analysis of Data from The Gothenburg H70 Birth Cohort Studies,
Sweden
Felicia Ahlner, Robert Sigström, Therese Rydberg Sterner, Madeleine Mellqvist Fässberg, Silke Kern, Svante Östling, Margda Waern, Ingmar Skoog
Alcoholism: Clinical and Experimental Research - 2018 -
Prevalence of preclinical Alzheimer disease Comparison of current classification
systems
Silke Kern, Henrik Zetterberg, Jürgen Kern, Anna Zettergren, Margda Waern, Kina Höglund, Ulf Andreasson, Hanna Wetterberg, Anne Börjesson-Hanson, Kaj Blennow, Ingmar Skoog
Neurology - 2018 -
A 10-Year Follow-Up of Adiposity and Dementia in Swedish Adults Aged 70 Years and
Older
I. A. C. Arnoldussen, Valter Sundh, Kristoffer Bäckman, Silke Kern, Svante Östling, Kaj Blennow, Henrik Zetterberg, Ingmar Skoog, Amanda Kiliaan, Deborah Gustafson
Journal of Alzheimers Disease - 2018 -
Low Cerebrospinal Fluid Aβ42 and Aβ40 are Related to White Matter Lesions in Cognitively Normal
Elderly.
Ingmar Skoog, Silke Kern, Henrik Zetterberg, Svante Östling, Anne Börjesson-Hanson, Xinxin Guo, Kaj Blennow
Journal of Alzheimer's disease : JAD - 2018 -
Subjective Sleep Disturbance is associated with preclinical Alzheimer’s Disease in Cerebrospinal Fluid in a Population-Based Study of 70-Year-Olds without
dementia.
Johan Skoog, Henrik Zetterberg, Kaj Blennow, Silke Kern, Valgeir Thorvaldsson, Ingmar Skoog, Boo Johansson
The 24th Nordic Conference of Gerontology, 2-4 May, Oslo, Norge - 2018 -
Poor Sleep Is Associated with CSF-Markers of Alzheimer’s Disease in 70-Year-Olds without
Dementia
Johan Skoog, Henrik Zetterberg, Kaj Blennow, Silke Kern, Boo Johansson, Ingmar Skoog, Valgeir Thorvaldsson
2018’s Alzheimer's Association International Conference, Chicago, USA. - 2018 -
Subjective Sleep Disturbance is associated with preclinical Alzheimer’s Disease in Cerebrospinal Fluid in a Population-Based Study of 70-Year-Olds without
dementia
Johan Skoog, Boo Johansson, Henrik Zetterberg, Kaj Blennow, Valgeir Thorvaldsson, Ingmar Skoog, Silke Kern
The 19th congress of the Section of Epidemiology and Social Psychiatry of the European Psychiatric Association (EPA), Wien, Österrike. - 2018 -
Increased risk of dementia in subjective cognitive decline if CT brain changes are
present
Simona Sacuiu, Marie Eckerström, Lena Johansson, Silke Kern, Robert Sigström, Xinxin Guo, Svante Östling, Ingmar Skoog
Journal of Alzheimer's Disease - 2018 -
Genetic variation in FOXO3 is associated with self-rated health in a population-based sample of older
individuals.
Anna Zettergren, Silke Kern, Lina Rydén, Svante Östling, Kaj Blennow, Henrik Zetterberg, Hanna Falk, Ingmar Skoog
The journals of gerontology. Series A, Biological sciences and medical sciences - 2018 -
Increased risk for dementia both before and after stroke: A population-based study in women followed over 44
years
Xinxin Guo, Svante Östling, Silke Kern, Lena Johansson, Ingmar Skoog
Alzheimers & Dementia - 2018 -
Midlife Stress in Relation to Late-Life Cerebrospinal Fluid Biomarkers of Alzheimer's Disease: A 25-Year Follow-Up
Study.
Lena Johansson, Silke Kern, Henrik Zetterberg, Kaj Blennow, Lars Rosengren, Xinxin Guo, Ingmar Skoog
Dementia and geriatric cognitive disorders - 2018 -
Midlife cardiovascular fitness and dementia A 44-year longitudinal population study in
women
Helena M Hörder, Lena Johansson, Xinxin Guo, Gunnar Grimby, Silke Kern, Svante Östling, Ingmar Skoog
Neurology - 2018 -
Author response: Calcium supplementation and risk of dementia in women with cerebrovascular
disease.
Silke Kern, Jürgen Kern, Kaj Blennow, Henrik Zetterberg, Margda Waern, Xinxin Guo, Anne Börjesson-Hanson, Ingmar Skoog, Svante Östling
Neurology - 2017 -
Multi-infarct dementia of Swedish type is caused by a 3'UTR mutation of
COL4A1.
Maija Siitonen, Anne Börjesson-Hanson, Minna Pöyhönen, Ari Ora, Petra Pasanen, Jose Bras, Silke Kern, Jürgen Kern, Oluf Andersen, Horia Stanescu, Robert Kleta, Marc Baumann, Rajesh Kalaria, H Kalimo, Andy Singleton, John Hardy, Matti Viitanen, Liisa Myllykangas, Rita Guerreiro
Brain : a journal of neurology - 2017 -
Expanding the cerebrospinal fluid
endopeptidome
Karl Hansson, Tobias Skillbäck, Elin Pernevik, Silke Kern, Erik Portelius, Kina Höglund, Gunnar Brinkmalm, Jessica Holmén Larsson, Kaj Blennow, Henrik Zetterberg, Johan Gobom
Proteomics - 2017 -
The relation between subjective sleep disturbance and Amyloid
β.
Johan Skoog, Silke Kern, Valgeir Thorvaldsson, Henrik Zetterberg, Kaj Blennow, Ingmar Skoog, Boo Johansson
IAGG-2017, San Francisco, USA: 23-27 july - 2017 -
Investigation of associations between ILRAP-related genetic variation and CSF-biomarkers of amyloid- and tangle pathology, AD-risk, and cognitive
decline.
Anna Zettergren, Silke Kern, Valgeir Thorvaldsson, Johan Skoog, Ingmar Skoog, Oskar Hansson, Henrik Zetterberg, Kaj Blennow, Kina Höglund
2017’s Alzheimer's Association International Conference (AAIC), London, Storbritannien: 16-20 July - 2017 -
Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts
Consortium
L. B. Chibnik, F. J. Wolters, Kristoffer Bäckman, A. Beiser, C. Berr, J. C. Bis, E. Boerwinkle, D. Bos, C. Brayne, J. F. Dartigues, S. K. L. Darweesh, S. Debette, K. L. Davis-Plourde, C. Dufouil, M. Fornage, L. Grasset, V. Gudnason, C. Hadjichrysanthou, C. Helmer, M. A. Ikram, M. K. Ikram, Silke Kern, L. H. Kuller, L. Launer, O. L. Lopez, F. Matthews, O. Meirelles, T. Mosley, A. Ower, B. M. Psaty, C. L. Satizabal, S. Seshadri, Ingmar Skoog, B. C. M. Stephan, C. Tzourio, R. Waziry, M. M. Wong, Anna Zettergren, A. Hofman
European Journal of Epidemiology - 2017 -
CSF YKL-40 and GAP-43 are related to suicidal ideation in older
women
Irma Rymo, Silke Kern, Maria Bjerke, Henrik Zetterberg, Thomas Marlow, Kaj Blennow, Pia Gudmundsson, Ingmar Skoog, Margda Waern
Acta Psychiatrica Scandinavica - 2017 -
Sex differences in time trends of blood pressure among Swedish septuagenarians examined three decades apart: a longitudinal population
study
Erik Joas, Xinxin Guo, Silke Kern, Svante Östling, Ingmar Skoog
Journal of Hypertension - 2017 -
Decreasing prevalence of dementia in 85-year olds examined 22 years apart: the influence of education and
stroke
Ingmar Skoog, Anne Börjesson-Hanson, Silke Kern, Lena Johansson, Hanna Falk, Robert Sigström, Svante Östling
Scientific Reports - 2017 -
Preclinical amyloid pathology biomarker positivity: effects on tau pathology and
neurodegeneration
Kina Höglund, Silke Kern, Anna Zettergren, Anne Börjesson-Hanson, Henrik Zetterberg, Ingmar Skoog, Kaj Blennow
Translational Psychiatry - 2017 -
Cerebrospinal Fluid Fatty Acid-Binding Protein 3 is Related to Dementia Development in a Population-Based Sample of Older Adult Women Followed for 8
Years.
Maria Bjerke, Silke Kern, Kaj Blennow, Henrik Zetterberg, Margda Waern, Anne Börjesson-Hanson, Svante Östling, Jürgen Kern, Ingmar Skoog
Journal of Alzheimer's disease : JAD - 2016 -
The Gothenburg MCI study: design and distribution of Alzheimer's disease and subcortical vascular disease diagnoses from baseline to 6-year
follow-up.
Anders Wallin, Arto Nordlund, Michael Jonsson, Karin Lind, Åke Edman, Mattias Göthlin, Jacob Stålhammar, Marie Eckerström, Silke Kern, Anne Börjesson-Hanson, Mårten Carlsson, Erik Olsson, Henrik Zetterberg, Kaj Blennow, Johan Svensson, Annika Öhrfelt Olsson, Maria Bjerke, Sindre Rolstad, Carl Eckerström
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 2016 -
Vascular factors in suspected normal pressure hydrocephalus. A population-based
study
Daniel Jaraj, Simon Agerskov, Katrin Rabiei, Thomas Marlow, Christer Jensen, Xinxin Guo, Silke Kern, Carsten Wikkelsö, Ingmar Skoog
Neurology - 2016 -
Calcium supplementation and risk of dementia in women with cerebrovascular
disease.
Jürgen Kern, Silke Kern, Kaj Blennow, Henrik Zetterberg, Margda Waern, Xinxin Guo, Anne Börjesson-Hanson, Ingmar Skoog, Svante Östling
Neurology - 2016 -
The distribution of apolipoprotein E genotype over the adult lifespan and in relation to country of
birth
Silke Kern, Kirsten Mehlig, Jürgen Kern, Henrik Zetterberg, Dag Thelle, Ingmar Skoog, Lauren Lissner, Kaj Blennow, Anne Börjesson-Hanson
American Journal of Epidemiology - 2015 -
A 9-Year Prospective Population-Based Study on the Association Between the APOE*E4 Allele and Late-Life Depression in
Sweden
Ingmar Skoog, Margda Waern, P Duberstein, Kaj Blennow, Henrik Zetterberg, Anne Börjesson-Hanson, Svante Östling, Xinxin Guo, Deborah Gustafson, Pia Gudmundsson, Thomas Marlow, Silke Kern
Biological Psychiatry - 2015 -
White Matter Lesions and Temporal Lobe Atrophy Related to incidence of both Dementia and Major Depression in 70-year-olds followed over 10
years
Pia Gudmundsson, Pernille J Olesen, Michela Simoni, Leonardo Pantoni, Svante Östling, Silke Kern, Xinxin Guo, Ingmar Skoog
European Journal of Neurology - 2015 -
Higher CSF interleukin-6 and CSF interleukin-8 in current depression in older women. Results from a population-based
sample.
Silke Kern, Ingmar Skoog, Anne Börjesson-Hanson, Kaj Blennow, Henrik Zetterberg, Svante Östling, Jürgen Kern, Pia Gudmundsson, Lars Rosengren, Margda Waern
Brain, behavior, and immunity - 2014 -
Lower CSF interleukin-6 predicts future depression in a population-based sample of older women followed for 17
years
Silke Kern, Ingmar Skoog, Anne Börjesson-Hanson, Kaj Blennow, Henrik Zetterberg, Svante Östling, Jürgen Kern, Pia Gudmundsson, Thomas Marlow, Lars Rosengren, Margda Waern
Brain Behavior and Immunity - 2013 -
Does low-dose acetylsalicylic acid prevent cognitive decline in women with high cardiovascular risk? A 5-year follow-up of a non-demented population-based cohort of Swedish elderly
women.
Silke Kern, Svante Östling, Ingmar Skoog, Jürgen Kern, Anne Börjesson-Hanson
BMJ Open - 2012