Juan Lantero Rodriguez
-
Levels of Alzheimer's disease blood biomarkers are altered after food intake-A pilot intervention study in healthy
adults
Hanna Huber, Nicholas J. Ashton, A. Schieren, Laia Montoliu-Gaya, Guglielmo Di Molfetta, Wagner S. Brum, Juan Lantero Rodriguez, Lana Grötschel, B. Stoffel-Wagner, M. Coenen, L. Weinhold, M. Schmid, Kaj Blennow, P. Stehle, Henrik Zetterberg, M. C. Simon
Alzheimers & Dementia - 2023 -
Mass spectrometric simultaneous quantification of tau species in plasma shows differential associations with amyloid and tau
pathologies
L. Montoliu-Gaya, Andréa Lessa Benedet, C. Tissot, A. Vrillon, Nicholas J. Ashton, Wagner S. Brum, Juan Lantero Rodriguez, J. Stevenson, Johanna Nilsson, Mathias Sauer, N. Rahmouni, Gunnar Brinkmalm, F. Z. Lussier, T. A. Pascoal, Ingmar Skoog, Silke Kern, Henrik Zetterberg, C. Paquet, Johan Gobom, P. Rosa-Neto, Kaj Blennow
Nature Aging - 2023 -
Plasma and CSF biomarkers in a memory clinic: Head-to-head comparison of phosphorylated tau
immunoassays
Nicholas J. Ashton, A. Puig-Pijoan, M. Mila-Aloma, A. Fernandez-Lebrero, G. Garcia-Escobar, Fernando Gonzalez-Ortiz, Przemyslaw R. Kac, Wagner S. Brum, Andréa Lessa Benedet, Juan Lantero Rodriguez, T. A. Day, J. Vanbrabant, E. Stoops, E. Vanmechelen, G. Triana-Baltzer, S. Moughadam, H. Kolb, P. Ortiz-Romero, Thomas Karikari, C. Minguillon, J. J. H. Sanchez, I. Navalpotro-Gomez, O. Grau-Rivera, R. M. Manero, V. Puente-Periz, R. de la Torre, J. Roquer, J. L. Dage, Henrik Zetterberg, Kaj Blennow, M. Suarez-Calvet
Alzheimers & Dementia - 2023 -
Head-to-head comparison of plasma p-tau181, p-tau231 and glial fibrillary acidic protein in clinically unimpaired elderly with three levels of APOE4-related risk for Alzheimer's
disease
Anniina Snellman, L. L. Ekblad, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, E. Pietila, M. Koivumaki, S. Helin, M. Karrasch, Henrik Zetterberg, Kaj Blennow, J. O. Rinne
Neurobiology of Disease - 2023 -
Plasma and CSF concentrations of N-terminal tau fragments associate with in vivo neurofibrillary tangle
burden
Juan Lantero Rodriguez, C. Tissot, Anniina Snellman, S. Servaes, Andréa Lessa Benedet, N. Rahmouni, Laia Montoliu-Gaya, J. Therriault, Wagner S. Brum, J. Stevenson, F. Z. Lussier, G. Bezgin, A. C. Macedo, M. Chamoun, S. S. Mathotaarachi, T. A. Pascoal, Nicholas J. Ashton, Henrik Zetterberg, P. R. Neto, Kaj Blennow
Alzheimers & Dementia - 2023 -
Plasma and cerebrospinal fluid glial fibrillary acidic protein levels in adults with Down syndrome: a longitudinal cohort
study
Laia Montoliu-Gaya, D. Alcolea, Nicholas J. Ashton, J. Pegueroles, J. Levin, B. Bosch, Juan Lantero Rodriguez, M. Carmona-Iragui, O. Wagemann, M. Balasa, Przemyslaw R. Kac, I. Barroeta, A. Llado, Wagner S. Brum, L. Videla, Fernando Gonzalez-Ortiz, B. Benejam, J. J. A. Martinez, Thomas Karikari, G. Nubling, A. Bejanin, Andréa Lessa Benedet, R. Blesa, A. Lleo, Kaj Blennow, R. Sanchez-Valle, Henrik Zetterberg, J. Fortea
eBioMedicine - 2023 -
Tau in cerebrospinal fluid induces neuronal hyperexcitability and alters hippocampal theta
oscillations
J. Brown, Elena Camporesi, Juan Lantero Rodriguez, M. Olsson, A. L. C. Wang, B. Medem, Henrik Zetterberg, Kaj Blennow, Thomas Karikari, M. Wall, E. Hill
Acta Neuropathologica Communications - 2023 -
Alzheimer Disease Blood Biomarkers in Patients With Out-of-Hospital Cardiac
Arrest
Nicholas J. Ashton, M. Moseby-Knappe, Andréa Lessa Benedet, Lana Grötschel, Juan Lantero Rodriguez, Thomas Karikari, C. Hassager, M. P. Wise, P. Stammet, J. Kjaergaard, H. Friberg, N. Nielsen, T. Cronberg, Henrik Zetterberg, Kaj Blennow
Jama Neurology - 2023 -
APOE epsilon 4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired
elderly
Anniina Snellman, L. L. Ekblad, J. Tuisku, M. Koivumaki, Nicholas J. Ashton, Juan Lantero Rodriguez, Thomas Karikari, S. Helin, M. Bucci, E. Loyttyniemi, R. Parkkola, M. Karrasch, Michael Schöll, Henrik Zetterberg, Kaj Blennow, J. O. Rinne
Alzheimers Research & Therapy - 2023 -
Clinical performance and head-to-head comparison of CSF p-tau235 with p-tau181, p-tau217 and p-tau231 in two memory clinic
cohorts
Juan Lantero Rodriguez, A. Vrillon, A. Fernandez-Lebrero, P. Ortiz-Romero, Anniina Snellman, Laia Montoliu-Gaya, Wagner S. Brum, E. Cognat, J. Dumurgier, A. Puig-Pijoan, I. Navalpotro-Gomez, G. Garcia-Escobar, Thomas Karikari, E. Vanmechelen, Nicholas J. Ashton, Henrik Zetterberg, M. Suarez-Calvet, C. Paquet, Kaj Blennow
Alzheimers Research & Therapy - 2023 -
Association of Phosphorylated Tau Biomarkers With Amyloid Positron Emission Tomography vs Tau Positron Emission
Tomography.
Joseph Therriault, Marie Vermeiren, Stijn Servaes, Cécile Tissot, Nicholas J. Ashton, Andréa Lessa Benedet, Thomas Karikari, Juan Lantero Rodriguez, Wagner S. Brum, Firoza Z Lussier, Gleb Bezgin, Jenna Stevenson, Nesrine Rahmouni, Peter Kunach, Yi-Ting Wang, Jaime Fernandez-Arias, Kely Quispialaya Socualaya, Arthur C Macedo, João Pedro Ferrari-Souza, Pâmela C L Ferreira, Bruna Bellaver, Douglas T Leffa, Eduardo R Zimmer, Paolo Vitali, Jean-Paul Soucy, Gallen Triana-Baltzer, Hartmuth C Kolb, Tharick A Pascoal, Paramita Saha-Chaudhuri, Serge Gauthier, Henrik Zetterberg, Kaj Blennow, Pedro Rosa-Neto
JAMA neurology - 2022 -
N-terminal and mid-region tau fragments as fluid biomarkers in neurological
diseases.
Anniina Snellman, Juan Lantero Rodriguez, Andreja Emeršič, Agathe Vrillon, Thomas Karikari, Nicholas J. Ashton, Milica Gregorič Kramberger, Saša Čučnik, Claire Paquet, Uroš Rot, Henrik Zetterberg, Kaj Blennow
Brain : a journal of neurology - 2022 -
Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical
utility
Thomas Karikari, Nicholas J. Ashton, Gunnar Brinkmalm, Wagner S. Brum, Andréa Lessa Benedet, Laia Montoliu-Gaya, Juan Lantero Rodriguez, T. A. Pascoal, M. Suarez-Calvet, P. Rosa-Neto, Kaj Blennow, Henrik Zetterberg
Nature Reviews Neurology - 2022 -
Plasma biomarkers for Alzheimer's Disease in relation to neuropathology and cognitive
change
D. S. Smirnov, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Joel Simrén, Juan Lantero Rodriguez, Thomas Karikari, A. Hiniker, R. A. Rissman, D. P. Salmon, D. Galasko
Acta Neuropathologica - 2022 -
Publisher Correction: Plasma p-tau231 and p-tau217 as state markers of amyloid-β pathology in preclinical Alzheimer's
disease.
Marta Milà-Alomà, Nicholas J. Ashton, Mahnaz Shekari, Gemma Salvadó, Paula Ortiz-Romero, Laia Montoliu-Gaya, Andréa Lessa Benedet, Thomas Karikari, Juan Lantero Rodriguez, Eugeen Vanmechelen, Theresa A Day, Armand González-Escalante, Gonzalo Sánchez-Benavides, Carolina Minguillon, Karine Fauria, José Luis Molinuevo, Jeffrey L Dage, Henrik Zetterberg, Juan Domingo Gispert, Marc Suárez-Calvet, Kaj Blennow
Nature medicine - 2022 -
Antibody-free measurement of cerebrospinal fluid tau phosphorylation across the Alzheimer's disease
continuum.
Johan Gobom, Andréa Lessa Benedet, Niklas Mattsson-Carlgren, Laia Montoliu-Gaya, Nina Schultz, Nicholas J. Ashton, Shorena Janelidze, Stijn Servaes, Mathias Sauer, Tharick A Pascoal, Thomas Karikari, Juan Lantero Rodriguez, Gunnar Brinkmalm, Henrik Zetterberg, Oskar Hansson, Pedro Rosa-Neto, Kaj Blennow
Molecular neurodegeneration - 2022 -
CSF biomarkers and plasma p-tau181 as predictors of longitudinal tau accumulation: Implications for clinical trial
design
Alexis Moscoso Rial, Thomas Karikari, Michel J. Grothe, Nicholas J. Ashton, Juan Lantero Rodriguez, Anniina Snellman, Henrik Zetterberg, Kaj Blennow, Michael Schöll
Alzheimer's and Dementia - 2022 -
Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's
disease
Nicholas J. Ashton, Andréa Lessa Benedet, Tharick A. Pascoal, Thomas Karikari, Juan Lantero Rodriguez, Wagner S. Brum, S. Mathotaarachchi, J. Therriault, M. Savard, M. Chamoun, E. Stoops, C. Francois, E. Vanmechelen, S. Gauthier, E. R. Zimmer, Henrik Zetterberg, Kaj Blennow, P. Rosa-Neto
Ebiomedicine - 2022 -
Plasma p-tau231, p-tau181, PET Biomarkers, and Cognitive Change in Older
Adults.
Pierre-François Meyer, Nicholas J. Ashton, Thomas Karikari, Cherie Strikwerda-Brown, Theresa Köbe, Julie Gonneaud, Alexa Pichet Binette, Hazal Ozlen, Yara Yakoub, Joel Simrén, Josef Pannee, Juan Lantero Rodriguez, Anne Labonté, Suzanne L Baker, Michael Schöll, Eugeen Vanmechelen, John C S Breitner, Henrik Zetterberg, Kaj Blennow, Judes Poirier, Sylvia Villeneuve
Annals of neurology - 2022 -
Biomarker modeling of Alzheimer’s disease using PET-based Braak
staging
J. Therriault, T. A. Pascoal, F. Z. Lussier, C. Tissot, M. Chamoun, G. Bezgin, S. Servaes, Andréa Lessa Benedet, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, P. Kunach, Y. T. Wang, J. Fernandez-Arias, G. Massarweh, P. Vitali, J. P. Soucy, P. Saha-Chaudhuri, Kaj Blennow, Henrik Zetterberg, S. Gauthier, P. Rosa-Neto
Nature Aging - 2022 -
Plasma p-tau231 and p-tau217 as state markers of amyloid-beta pathology in preclinical Alzheimer's
disease
M. Mila-Aloma, Nicholas J. Ashton, M. Shekari, G. Salvado, P. Ortiz-Romero, Laia Montoliu-Gaya, Andréa Lessa Benedet, Thomas Karikari, Juan Lantero Rodriguez, E. Vanmechelen, T. A. Day, A. Gonzalez-Escalante, G. Sanchez-Benavides, C. Minguillon, K. Fauria, J. L. Molinuevo, J. L. Dage, Henrik Zetterberg, J. D. Gispert, M. Suarez-Calvet, Kaj Blennow
Nature Medicine - 2022 -
Novel cerebrospinal fluid and blood tau biomarkers in Alzheimer's disease and other neurodegenerative
diseases
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P-tau235: a novel biomarker for staging preclinical Alzheimer's
disease.
Juan Lantero Rodriguez, Anniina Snellman, Andréa Lessa Benedet, Marta Milà-Alomà, Elena Camporesi, Laia Montoliu-Gaya, Nicholas J. Ashton, Agathe Vrillon, Thomas Karikari, Juan Domingo Gispert, Gemma Salvadó, Mahnaz Shekari, Christina E Toomey, Tammaryn L Lashley, Henrik Zetterberg, Marc Suárez-Calvet, Gunnar Brinkmalm, Pedro Rosa Neto, Kaj Blennow
EMBO molecular medicine - 2021 -
Phosphorylated tau181 in plasma as a potential biomarker for Alzheimer's disease in adults with Down
syndrome
A. Lleo, Henrik Zetterberg, J. Pegueroles, Thomas Karikari, M. Carmona-Iragui, Nicholas J. Ashton, V. Montal, I. Barroeta, Juan Lantero Rodriguez, L. Videla, M. Altuna, B. Benejam, S. Fernandez, S. Valldeneu, D. Garzon, A. Bejanin, M. F. Iulita, V. Camacho, S. Medrano-Martorell, O. Belbin, J. Clarimon, S. Lehmann, D. Alcolea, R. Blesa, Kaj Blennow, J. Fortea
Nature Communications - 2021 -
Plasma p-tau231: a new biomarker for incipient Alzheimer's disease
pathology.
Nicholas J. Ashton, Tharick A Pascoal, Thomas Karikari, Andréa Lessa Benedet, Juan Lantero Rodriguez, Gunnar Brinkmalm, Anniina Snellman, Michael Schöll, Claire Troakes, Abdul Hye, Serge Gauthier, Eugeen Vanmechelen, Henrik Zetterberg, Pedro Rosa-Neto, Kaj Blennow
Acta neuropathologica - 2021 -
Neuroligin-1 in brain and CSF of neurodegenerative disorders: investigation for synaptic
biomarkers
Elena Camporesi, T. Lashley, Johan Gobom, Juan Lantero Rodriguez, O. Hansson, Henrik Zetterberg, Kaj Blennow, Bruno Becker
Acta Neuropathologica Communications - 2021 -
Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer
Disease.
Alexis Moscoso Rial, Michel J. Grothe, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, Anniina Snellman, Marc Suárez-Calvet, Kaj Blennow, Henrik Zetterberg, Michael Schöll
JAMA Neurology - 2021 -
Effects of pre-analytical procedures on blood biomarkers for Alzheimer's pathophysiology, glial activation, and
neurodegeneration.
Nicholas J. Ashton, Marc Suárez-Calvet, Thomas Karikari, Juan Lantero Rodriguez, Anniina Snellman, Joel Simrén, Carolina Minguillon, Karine Fauria, Kaj Blennow, Henrik Zetterberg
Alzheimer's & dementia (Amsterdam, Netherlands) - 2021 -
Association between polygenic risk score of Alzheimer's disease and plasma phosphorylated tau in individuals from the Alzheimer's Disease Neuroimaging
Initiative.
Anna Zettergren, Jodie Lord, Nicholas J. Ashton, Andréa Lessa Benedet, Thomas Karikari, Juan Lantero Rodriguez, Anniina Snellman, Marc Suárez-Calvet, Petroula Proitsi, Henrik Zetterberg, Kaj Blennow
Alzheimer's research & therapy - 2021 -
Time course of phosphorylated-tau181 in blood across the Alzheimer's disease
spectrum.
Alexis Moscoso Rial, Michel J. Grothe, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, Anniina Snellman, Marc Suarez-Calvet, Henrik Zetterberg, Kaj Blennow, Michael Schöll
Brain : a journal of neurology - 2021 -
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer's Disease Neuroimaging
Initiative.
Thomas Karikari, Andréa L Benedet, Nicholas J. Ashton, Juan Lantero Rodriguez, Anniina Snellman, Marc Suárez-Calvet, Paramita Saha-Chaudhuri, Firoza Lussier, Hlin Kvartsberg, Alexis Moscoso Rial, Tharick A Pascoal, Ulf Andreasson, Michael Schöll, Michael W Weiner, Pedro Rosa-Neto, John Q Trojanowski, Leslie M Shaw, Kaj Blennow, Henrik Zetterberg
Molecular psychiatry - 2021 -
Truncating tau reveals different pathophysiological actions of oligomers in single
neurons
E. Hill, Thomas Karikari, Juan Lantero Rodriguez, Henrik Zetterberg, Kaj Blennow, M. J. Richardson, M. J. Wall
Communications Biology - 2021 -
Associations of Fully Automated CSF and Novel Plasma Biomarkers With Alzheimer Disease Neuropathology at
Autopsy.
Michel J. Grothe, Alexis Moscoso Rial, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, Anniina Snellman, Henrik Zetterberg, Kaj Blennow, Michael Schöll
Neurology - 2021 -
Transitioning from cerebrospinal fluid to blood tests to facilitate diagnosis and disease monitoring in Alzheimer's
disease.
Deborah O T Alawode, Amanda J Heslegrave, Nicholas J. Ashton, Thomas Karikari, Joel Simrén, Laia Montoliu-Gaya, Josef Pannee, Antoinette O Connor, Philip S J Weston, Juan Lantero Rodriguez, Ashvini Keshavan, Anniina Snellman, Johan Gobom, Ross W Paterson, Jonathan M Schott, Kaj Blennow, Nick C Fox, Henrik Zetterberg
Journal of internal medicine - 2021 -
The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's
disease.
Joel Simrén, Antoine Leuzy, Thomas Karikari, Abdul Hye, Andréa Lessa Benedet, Juan Lantero Rodriguez, Niklas Mattsson-Carlgren, Michael Schöll, Patrizia Mecocci, Bruno Vellas, Magda Tsolaki, Iwona Kloszewska, Hilkka Soininen, Simon Lovestone, Dag Aarsland, Oskar Hansson, Pedro Rosa-Neto, Eric Westman, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2021 -
Head-to-head comparison of clinical performance of CSF phospho-tau T181 and T217 biomarkers for Alzheimer's disease
diagnosis.
Thomas Karikari, Agathe Vrillon, Juan Lantero Rodriguez, Nicholas J. Ashton, Milica Gregorič Kramberger, Julien Dumurgier, Claire Hourregue, Saša Čučnik, Gunnar Brinkmalm, Uroš Rot, Henrik Zetterberg, Claire Paquet, Kaj Blennow
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2021 -
Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer's continuum when only subtle changes in Aβ pathology are
detected.
Marc Suárez-Calvet, Thomas Karikari, Nicholas J. Ashton, Juan Lantero Rodriguez, Marta Milà-Alomà, Juan Domingo Gispert, Gemma Salvadó, Carolina Minguillon, Karine Fauria, Mahnaz Shekari, Oriol Grau-Rivera, Eider M Arenaza-Urquijo, Aleix Sala-Vila, Gonzalo Sánchez-Benavides, José Maria González-de-Echávarri, Gwendlyn Kollmorgen, Erik Stoops, Eugeen Vanmechelen, Henrik Zetterberg, Kaj Blennow, José Luis Molinuevo
EMBO molecular medicine - 2020 -
An extensive plasmid library to prepare tau protein variants and study their functional
biochemistry.
Thomas Karikari, Sophie Keeling, Emily Hill, Juan Lantero Rodriguez, David A Nagel, Bruno Becker, Kina Höglund, Henrik Zetterberg, Kaj Blennow, Eric J Hill, Kevin G Moffat
ACS chemical neuroscience - 2020 -
Plasma p-tau181 accurately predicts Alzheimer's disease pathology at least 8 years prior to post-mortem and improves the clinical characterisation of cognitive
decline.
Juan Lantero Rodriguez, Thomas Karikari, Marc Suárez-Calvet, Claire Troakes, Andrew King, Andreja Emersic, Dag Aarsland, Abdul Hye, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton
Acta neuropathologica - 2020 -
Diagnostic and prognostic value of serum NfL and p-Tau181 in frontotemporal lobar
degeneration.
Alberto Benussi, Thomas Karikari, Nicholas J. Ashton, Stefano Gazzina, Enrico Premi, Luisa Benussi, Roberta Ghidoni, Juan Lantero Rodriguez, Andreja Emersic, Joel Simrén, Giuliano Binetti, Silvia Fostinelli, Marcello Giunta, Roberto Gasparotti, Henrik Zetterberg, Kaj Blennow, Barbara Borroni
Journal of neurology, neurosurgery, and psychiatry - 2020 -
Serum Glial Fibrillary Acidic Protein (GFAP) Is a Marker of Disease Severity in Frontotemporal Lobar
Degeneration.
Alberto Benussi, Nicholas J. Ashton, Thomas Karikari, Stefano Gazzina, Enrico Premi, Luisa Benussi, Roberta Ghidoni, Juan Lantero Rodriguez, Andreja Emersic, Giuliano Binetti, Silvia Fostinelli, Marcello Giunta, Roberto Gasparotti, Henrik Zetterberg, Kaj Blennow, Barbara Borroni
Journal of Alzheimer's disease : JAD - 2020 -
Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective
cohorts.
Thomas Karikari, Tharick A Pascoal, Nicholas J. Ashton, Shorena Janelidze, Andréa Lessa Benedet, Juan Lantero Rodriguez, Mira Chamoun, Melissa Savard, Min Su Kang, Joseph Therriault, Michael Schöll, Gassan Massarweh, Jean-Paul Soucy, Kina Höglund, Gunnar Brinkmalm, Niklas Mattsson, Sebastian Palmqvist, Serge Gauthier, Erik Stomrud, Henrik Zetterberg, Oskar Hansson, Pedro Rosa-Neto, Kaj Blennow
The Lancet. Neurology - 2020 -
Obesity-induced changes in lipid mediators persist after weight
loss
A. Hernandez-Carretero, N. Weber, M. R. La Frano, W. Ying, Juan Lantero Rodriguez, D. D. Sears, Ville Wallenius, Emma Börgeson, J. W. Newman, O. Osborn
International Journal of Obesity - 2018 -
AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent of
adiponectin.
Emma Börgeson, Ville Wallenius, Gulam H Syed, Manjula Darshi, Juan Lantero Rodriguez, Christina Biörserud, Malin Ragnmark Ek, Per Björklund, Marianne Quiding-Järbrink, Lars Fändriks, Catherine Godson, Kumar Sharma
Diabetologia - 2017