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Göteborgs universitet
Foto från en livmodertransplantation på Sahlgrenska sjukhuset
Mats Brännström med team under pågående operation på en donator på Sahlgrenska universitetssjukhuset.
Foto: Johan Wingborg

Vetenskapliga publikationer från forskningsprojekten om livmodertransplantationer

På denna sida hittar du ett urval av de vetenskapliga publikationer som har publicerats från de världsledande forskningsprojekten om livmodertransplantationer.


Brännström M. Current status and future direction of uterus transplantation. Current Opinion in Organ Transplantation. October 2018 - Volume 23 - Issue 5 - p 592–597.



Johannesson L, Kvarnström N, Mölne J, Dahm-Kähler P, Enskog AS, Diaz-Garcia C, Olausson M, Brännström M. Uterus transplantation trial: 1-year outcome. Fertil Steril 2015; 103:199-204

Brännström M, Johannesson L, Bokström H, Kvarnström N, Mölne J, Dahm-Kähler P, Enskog A, Milenkovic M, Ekberg J, Diaz-Garcia C, Gäbel M, Hanafy A, Hagberg H, Olausson M, Nilsson L. Live birth after uterus transplantation. Lancet 2015;385:607-616



Tryphonopoulos P, Tzakis AG, Tekin A, Johannesson L, Rivas K, Morales PR, Wagner J, Mölne J, Enskog E, Diaz-Garcia C, Dahm-Kähler P, Berho M, Zimberg S, Falcone T, Ruiz P, Olausson M, Brännström M. Allogeneic uterus transplantation in baboons: surgical technique and challenges to long-term graft survival. Transplantation 2014;98:51-56

Brännström M, Johannesson L, Dahm-Kähler P, Enskog AS, Mölne J, Kvarnström N, Diaz-Garcia C, Hanafy A, Lundmark C, Marcickiewicz J, Gäbel M, Groth K, Akouri R, Eklind S, Holgersson J, Tzakis A, Olausson M. The first clinical uterus transplantation trial: a six months report. Fertil Steril 2014; 101:1228-36

Diaz-Garcia C, Johannesson L, Shao R, Billig H, Brännström M. Pregnancy after allogeneic uterus transplantation in the rat: perinatal outcome and growth trajectory. Fertil Steril 2014; 102:1545-52

Hellström M, El-Akouri RR, Sihlbom C, Olsson BM, Lengqvist J, Bäckdahl H, Johansson BR, Olausson M, Sumitran-Holgersson S, Brännström M. Towards development of a bioengineered uterus: comparison of different protocols for rat uterus decellularization. Acta Biomater 2014, 10:5034-5042

Olausson M, Johannesson L, Brattgård D, Diaz-Garcia C, Lundmark, C, Groth K, Marcickiewizc J, Enskog A, Akouri R, Tzakis A, Rogiers X, Janson PO, Brännström M. Ethics of uterus transplantation with live donors. Fertil Steril 2014;102:40-3

Johannesson L, Dahm-Kähler P, Eklind S, Brännström M. The future of human uterus transplantation. Womens Health (Lond Engl) 2014; 10:456-467



Johannesson L, Enskog A, Mölne J, Diaz-Garcia C, Hanafy A, Dahm-Kähler P, Tekin A, Tryphonopoulos P, Morales P, Rivas K, Ruiz P, Tzakis A, Olausson M, Brännström M. Preclinical report on allogeneic uterus transplantation in non-human primates. Hum Reprod 2013;28: 189-198

Diaz-Garcia C, Akhi SN, Martinez-Varea A, Brännström M. The effect of warm ischemia at uterus transplantation in a rat model. Acta Obstet Gynecol Scand 2013;92:152-159

Akhi SN, Diaz-Garcia C, El-Akouri RR Wranning CA, Mölne J, Brännström M. Uterine rejection after allogeneic uterus transplantation in the rat is effectively suppressed by tacrolimus. Fertil Steril 2013;99:862-870

Del Priore G, Saso S, Meslin EM, Tzakis A, Brännström M, Clarke A, Vianna A, Sawyer R Smith JR. Uterine transplantation – a real possibility? The Indianapolis consensus. Hum Reprod 2013;28:288-291

Brännström M. Uterus transplantation: Fertil Steril 2013;99:348-349

Dancet EA, Brännström M, Brasky K, Chai D et al. The role of scientists and clinicians in raising public support for animal research in reproductive biology and medicine. Biol Reprod 2013;88:33

Diaz-Garcia C, Brännström M. Uterus transplantation: potential patients, fertility and ethics. J Reprod Med Endocrinol 2013;9:1-10

Johannesson L, Enskog A, Kvarnström N, Brännström M. Uterus transplantation: non-human primate research and human cases. J E Fert Soc 2013; 12:12-24



Groth K, Akhi S, Mölne J, Wranning CA, Brännström M. Effects of immunosuppression by cyclosporine A on allogenic uterine transplant in the rat. Eur J Obstet Gynecol Reprod Biol 2012;91:952-958

Johannesson L, Enskog A, Dahm-Kähler P, Hanafy A, Chai DC, Mwenda JM, Diaz-Garcia C, Olausson M, Brännström M. Uterus transplantation in a non-human primate: long-term follow up after autologous transplantation. Hum Reprod 2012;27:1640-1648

Johannesson L, Diaz-Garcia C, Leonhardt H, Dahm-Kähler P, Marcickiewicz J, Olausson M, Brännström M. Vascular pedicle lengths after hysterectomy: toward future human uterus transplantation. Obstet Gynecol 2012;119:1219-1225

Diaz-Garcia C, Johannesson L, Enskog A, Tzakis A, Olausson M, Brännström M. Uterus transplantation research: laboratory protocols for clinical application. Mol Hum Reprod 2012;18:68-78

Brännström M, Diaz-Garcia C, Olausson M, Tzakis A. Uterus transplantation: animal research and human possibilities. Fertil Steril 2012;97:169-1276



Wranning CA, Akhi SN, Diaz-Garcia C, Brännström M. Pregnancy after syngeneic uterus transplantation and spontaneous mating in the rat. Hum Reprod 2011;26:553-558

Brännström M, Diaz-Garcia C, Transplantation of female genital organs. J Obstet Gynaecol Res 2011:37:271-291

Hanafy H, Diaz-Garcia C, Olausson M, Brännström M. Uterine transplantation: one human case followed by a decade of experimental research in animal models. Aust N Z J Obstet Gynaecol 2011;51:199-203



Groth K, Brännström M, Mölne J, Wranning CA. Cyclosporine A exposure during pregnancy in mice: effects on reproductive performance in mothers and offspring. Hum Reprod 2010;25:697-704

Wranning CA, Marcickiewicz J, Enskog A, Dahm-Kähler P, Hanafy A, Brännström M. Fertility after autologous ovine uterine-tubal-ovarian transplantation by vascular anastomosis to the external iliac vessels. Hum Reprod 2010;25:1973-1979

Enskog A, Johannesson L, Chai DC, Dahm-Kähler P, Marcickiewicz J, Nyachieo A, Mwenda J, Brännström M. Uterus transplantation in the baboon: methodology and long-term function after auto-transplantation. Hum Reprod 2010;25:1980-1987

Diaz-Garcia C, Akhi SN, Wallin A, Pellicer A, Brännström M. First report on fertility after allogeneic uterus transplantation. Acta Obstet Gynecol Scand 2010;89:1491-1494

Brännström M, Wranning CA, Altchek A. Experimental uterus transplantation. Hum Reprod Update 2010;16:329-345



Groth K, El-Akouri RR, Wranning CA, Mölne J, Brännström M. Rejection of allogenic uterus transplant in the mouse: time-dependent and site-specific infiltration of leukocyte subtypes. Hum Reprod 2009;24:2746-2754



Wranning CA, Dahm-Kähler P, Mölne J, Nilsson UA, Enskog A, Brännström M. Transplantation of the uterus in the sheep – oxidative stress and reperfusion injury after short-time cold storage. Fertil Steril 2008;90:817-826

Wranning CA, Akhi SN, Kurlberg G, Brännström M. Uterus transplantation in the rat: model development, surgical learning and morphological evaluation. Acta Obstet Gynecol Scand 2008;87:1239-1247

Dahm-Kähler P, Wranning CA, Lundmark C, Enskog A, Mölne J, Marcickiewicz J, El-Akouri RR, McCracken JA, Brännström M. Transplantation of the uterus in the sheep: methodology and early reperfusion events. J Obstet Gynaecol Res 2008;34:784-793

Brännström M, Wranning CA. Uterus transplantation: how far away from human trials? Acta Obstet Gynecol Scand 2008;87:1097-1100



Wranning CA, El-Akouri RR, Groth K, Mölne J, Parra AK, Brännström M. Rejection of the transplanted uterus is suppressed by cyclosporine A in a semi-allogeneic mouse model. Hum Reprod 2007;22:372-379

Brännström M, Wranning CA. Uterus transplantation – where do we stand today and where should we go? Expert Opin Biol Ther 2007;7:427-429

Brännström M, Wranning CA, Marcickiewicz J, Enskog A, Hanafy A. Uterus transplantation – substantial progress in research but not yet ready for the clinic. MEFS Journal 2007;12:86-95

Brännström M. Uterine transplantation: a future possibility to treat women with uterus factor infertility? Minerva Med 2007;98:211-216



Wranning CA, Mölne J, Racho El-Akouri R, Kurlberg G, Brännström M. Short-term ischaemic storage of human uterine myometrium – basic studies towards uterine transplantation. Human Reprod 2005;20:2736-2744



Dahm-Kähler P, Löfman C, Fujii R, Axelsson M, Janson PO, Brännström M. An intravital microscopy method permitting continuous long-term observations of ovulation in vivo in the rabbit. Human Reprod 2006; 21:624-631

Racho El-Akouri R, Groth K, Kurlberg G, Mölne J, Brännström M. Rejection patterns in allogeneic uterus transplantation in the mouse. Hum Reprod 2006;21:436-442

Wranning CA, Racho El-Akouri R, Lundmark C, Dahm-Kähler P, Mölne J, Enskog A, Brännström M. Autotransplantation of the uterus in the domestic pig: surgical technique and early reperfusion events. J Obstet Gynecol Res 2006;32:358-367



Racho El-Akouri R, Wranning CA, Mölne J, Kurlberg G, Brännström M. Pregnancy in transplanted mouse uterus after long-term cold ischaemic preservation. Hum Reprod. 2003;18:2024-2030

Racho El-Akouri R, Kurlberg G, Brännström M. Successful uterine transplantation in the mouse: pregnancy and postnatal development of offspring. Hum Reprod. 2003;18:2018-2023

Brännström M, El-Akouri RR, Wranning CA. Uterine transplantation. Eur J Obstet Gynecol Reprod Biol 2003;109:121-123

Brännström M, Wranning CA, El-Akouri RR. Transplantation of the uterus. Mol Cell Endocrinol 2003;202:177-184



Racho El-Akouri R, Kurlberg G, Dindelegan G, Mölne J, Wallin A, Brännström M. Heterotopic uterine transplantation by vascular anastomosis in the mouse. J Endocrinol 2002;174:157-166