About us
Core Facilities offer access to advanced research infrastructures, research support and training. Our facilities are located at The Sahlgrenska Academy, and are open to all researchers. We have the aim of delivering high-quality support, tailored to meet individual research needs.
Our centres offer consultation within the newest technologies, as well as in experimental design and analysis to ensure the best possible research outcomes.
Our support include consultation in designing experiments, access to advanced equipment and novel technologies, as well as assistance in the execution of a project, sample preparation and data collection.
Specialized technical training and analysis tools for data evaluation and bioinformatics are also offered.
In addition, the Core Facilities are dedicated to continuing education and arrange courses, workshops and seminars for the research community.
If you are interested in instrumentation outside Core Facilities, please go to the link to our Swedish pages.
SciLifeLab
Sequence, Analyze, Visualize, and Integrate ‘Big Data’
The Bioinformatics Data Center (BDC) provides new high-throughput techniques, e.g. next-generation sequencing (NGS) for clinical and preclinical research as part of Genomic Medicine Sweden (GMS) and SciLifeLab Clinical Genomics, together with bioinformatics and statistics expertise in analysis, data integration and visualization that facilitates meaningful and trustworthy cutting-edge biomedical research.
Advanced Multimodal Imaging
The Centre for Cellular Imaging (CCI) provides state-of-the-art imaging equipment that integrates advanced light (LM) and electron microscopy (EM). Highly competent and specialized personnel consult in design of microscopy and image analysis experiments. Theoretical and unique hands-on training enable the researchers to independently run the microscopes. Complete project solutions as well as independent training are offered, whether the researcher requires image analysis on powerful hardware or sample preparation for EM.
State-of-the-Art Support for Animal Research & Education
Experimental Biomedicine (EBM) is a first-class, multifunctional research facility providing infrastructure, expertise and education for research involving laboratory animals with a full-service concept, including housing and veterinary care as well as study support. EBM is also a national center for skills training has a core hub for advanced instruments, including an MRI-imaging facility. The principles of the 3Rs (Replacement, Refinement, Reduction) are integrated into all EBM policies and operations.
Complex Recombinant Proteins & Monoclonal Antibodies
At the Mammalian Protein Expression Core Facility (MPE), mammalian cells are used to produce complex recombinant proteins and glycoproteins. These proteins can be crucial research reagents, and support include all steps from fit-for-purpose protein design to purification. Additionally, the facility can help with production of monoclonal antibodies and culturing of cell lines. As part of the national infrastructure Protein Production Sweden (PPS), researchers can turn to MPE to get proteins produced also in other expression systems.
Design & Synthesis of Therapeutic Oligonucleotides
The OligoNova Hub is a national infrastructure for drug development, focused on therapeutic oligonucleotides. The goal is to help researchers convert their research results into new drugs for patient groups who currently lack appropriate treatment. Supports the full process from design and synthesis of oligonucleotides to evaluation of efficiency and toxicity.
Cutting-Edge Mass Spectrometry-Based Protein Analysis
The Proteomics Core Facility offers the newest instrumentation for mass spectrometry analysis. Our methods can be custom-fitted and includes eg. quantitative, differential, clinical, phospho-, glyco- and interaction proteomics. Specialized apparatus to set up study of lower abundant proteins in complex biological samples including FFPE material is available. Our
experts assist in study design, preparations and data analysis.
Sample Service Coordination Across Sweden
The Biobank Core Facility provides national sample service coordination and offers both operational services, such as sample collection, sample handling, DNA and PBMC extraction, as well as regulatory support, such as ethical applications, inform consent and Material Transfer Agreements (MTA). Full traceability of each biobank sample is kept using IT systems in collaboration with Biobank Väst.
News from Core Facilities
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Health and medicineNew machine learning framework developed for quick radiation biomarkerdiscovery
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Health and medicineCALL4HELP in Light Microscopy, Image Acquisition &Analysis
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Health and medicineCloud compute solutions for new opportunities in precisionmedicine
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Health and medicineThe Centre for Cellular Imaging Swedish partner in two grants from the Chan Zuckerberg Initiative
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EventFour Projects Selected After a Record Number of Applications for the Bollan Stipend2022