Core Facilities
Core Facilities is a university-wide life science research infrastructure located at Sahlgrenska Academy. It provides access to some of Sweden's most advanced technology and analysis tools for research in eg. medicine, biomedicine, clinical studies and science.
In addition to highly qualified research support, our experts offer theoretical education and practical courses. Our open-access infrastructure welcomes researchers from Sweden and abroad as well as industry. Core Facilities is involved in networks and collaborations in Sweden and internationally.
Sequence, Analyze, Visualize, and Integrate ‘Big Data’
The Bioinformatics Data Center (BDC) provides new high-throughput techniques, e.g. next-generation sequencing (NGS) for clinical and preclinical research as part of Genomic Medicine Sweden (GMS) and SciLifeLab Clinical Genomics, together with bioinformatics and statistics expertise in analysis, data integration and visualization that facilitates meaningful and trustworthy cutting-edge biomedical research.
Advanced Multimodal Imaging
The Centre for Cellular Imaging (CCI) provides state-of-the-art imaging equipment that integrates advanced light (LM) and electron microscopy (EM). Highly competent and specialized personnel consult in design of microscopy and image analysis experiments. Theoretical and unique hands-on training enable the researchers to independently run the microscopes. Complete project solutions as well as independent training are offered, whether the researcher requires image analysis on powerful hardware or sample preparation for EM.
State-of-the-Art Support for Animal Research & Education
Experimental Biomedicine (EBM) is a first-class, multifunctional research facility providing infrastructure, expertise and education for research involving laboratory animals with a full-service concept, including housing and veterinary care as well as study support. EBM is also a national center for skills training has a core hub for advanced instruments, including an MRI-imaging facility. The principles of the 3Rs (Replacement, Refinement, Reduction) are integrated into all EBM policies and operations.
Complex Recombinant Proteins & Monoclonal Antibodies
At the Mammalian Protein Expression Core Facility (MPE), mammalian cells are used to produce complex recombinant proteins and glycoproteins. These proteins can be crucial research reagents, and support include all steps from fit-for-purpose protein design to purification. Additionally, the facility can help with production of monoclonal antibodies and culturing of cell lines. As part of the national infrastructure Protein Production Sweden (PPS), researchers can turn to MPE to get proteins produced also in other expression systems.
Cutting-Edge Mass Spectrometry-Based Protein Analysis
The Proteomics Core Facility offers the newest instrumentation for mass spectrometry analysis. Our methods can be custom-fitted and includes eg. quantitative, differential, clinical, phospho-, glyco- and interaction proteomics. Specialized apparatus to set up study of lower abundant proteins in complex biological samples including FFPE material is available. Our
experts assist in study design, preparations and data analysis.
Design & Synthesis of Therapeutic Oligonucleotides
The OligoNova Hub is a national infrastructure for drug development, focused on therapeutic oligonucleotides. The goal is to help researchers convert their research results into new drugs for patient groups who currently lack appropriate treatment. Supports the full process from design and synthesis of oligonucleotides to evaluation of efficiency and toxicity.
Sample Service Coordination Across Sweden
The Biobank Core Facility provides national sample service coordination and offers both operational services, such as sample collection, sample handling, DNA and PBMC extraction, as well as regulatory support, such as ethical applications, inform consent and Material Transfer Agreements (MTA). Full traceability of each biobank sample is kept using IT systems in collaboration with Biobank Väst.
News
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Health and medicine2025-03-07
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Health and medicine2025-03-03
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Health and medicine2025-01-16
