University of Gothenburg
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Fusion Lumos mass spectrometer at the Proteomics Core Facility
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Proteomics (PCF)

The Proteomics Core Facility is a research infrastructure available for researchers at Sahlgrenska Academy at Gothenburg University and external customers from other universities or industry.

Our research support includes study design, protein identification, characterization of post-translational modifications, as well as protein interaction analysis. The majority of projects we are involved in are discovery proteomic analyses, in which thousands of proteins can be identified and quantified in an unbiased manner.
The Proteomics Core Facility has experience regarding preparation of a huge range of samples originating from tissues, cells, isolated cellular compartments, pull-downs, other biological samples, or expressed proteins. High pH liquid chromatography fractionation prior to nano LC-MS is used for in-depth analysis and to study lower abundant proteins in complex biological samples. The facility is equipped with the latest high-resolution mass spectrometers.
We provide comprehensive data analysis through a variety of database search engines (Mascot, Sequest) and software packages (Proteome Discoverer, Byonics and MaxQuant). PCF is involved in approximately 300 projects per year.

Research Networks

BioMS

Since 2016 we are one of the nodes of the Swedish National Infrastructure for Biological Mass Spectrometry, BioMS, supported by the Swedish Research Council. For projects within Clinical Proteomics and Large Scale Quantitative Proteomics contact our project coordinator Annika Thorsell. Moreover, Ekaterina Mirgorodskaya is coordinating projects within Glycoproteomics and Glycomics. Please read more on the BioMS webpage.

 

SciLifeLab

In 2021, we joined the Science for Life Laboratory, a national research infrastructure funded by the Swedish government. Within the Proteomics units, we are supporting glycoproteomics and glycomics projects. Please find more information on the SciLifeLab homepage.