Håkan Billig
Om Håkan Billig
Research group
Physiology of the Fallopian Tube and Ectopic Pregnancy
Research interest
Female reproductive endocrinology has remained my primary research interest throughout my research career I have had the opportunity to work on several levels: molecular, cellular, systemic and both in experimental animal models as well in clinical settings and patient materials.
My research focus has developed based on the knowledge we have acquired and in parallel with the fast evolving international research in our and adjacent fields of research and with introduction of new techniques:
- ovarian metabolism (-1988)
- growth factor and GH effects on reproduction (1988-1995)
- follicular development and gonadal apoptosis (1990-2009)
- function of and metabolic regulation by prolactin on metabolism (2000-2011)
- progesterone and estrogen receptor subtype regulation and function in reproductive tissues (2003-2012)
- Fallopian tube physiology and tubal ectopic pregnancy (2006-2012)
-
Defective uterine spiral artery remodelling and placental senescence in a pregnant rat model of polycystic ovary
syndrome.
Min Hu, Yuehui Zhang, Xu Zhang, XiuYing Zhang, Xinyue Huang, Yaxing Lu, Yijia Li, Mats Brännström, Amanda Nancy Sferruzzi-Perri, Linus Ruijin Shao, Håkan Billig
The American journal of pathology - 2023 -
Regulatory mechanisms of HMGB1 and its receptors in polycystic ovary syndrome-driven gravid uterine
inflammation.
Min Hu, Yuehui Zhang, Yaxing Lu, Jing Han, Tingting Guo, Peng Cui, Mats Brännström, Linus Ruijin Shao, Håkan Billig
The FEBS journal - 2023 -
Overactivation of the androgen receptor exacerbates gravid uterine ferroptosis via interaction with and suppression of the NRF2 defense signaling
pathway.
Min Hu, Yuehui Zhang, Lingjing Lu, Yu Zhou, Denghui Wu, Mats Brännström, Linus Ruijin Shao, Håkan Billig
FEBS letters - 2022 -
Person-centered care content in medicine, occupational therapy, nursing, and physiotherapy education
programs
Catarina Wallengren Gustafsson, Håkan Billig, Ida Björkman, Inger Ekman, Caroline Feldthusen, Irma Lindström Kjellberg, Mari Lundberg
BMC medical education - 2022 -
TLR4-associated IRF-7 and NFĸB signaling acts as a molecular link between androgen and metformin activities and cytokine synthesis in the PCOS
endometrium.
Min Hu, Yuehui Zhang, Xin Li, Peng Cui, Amanda Nancy Sferruzzi-Perri, Mats Brännström, Linus Ruijin Shao, Håkan Billig
The Journal of clinical endocrinology and metabolism - 2021 -
Suppression of uterine and placental ferroptosis by N-acetylcysteine in a rat model of polycystic ovary
syndrome.
Min Hu, Yuehui Zhang, Shuting Ma, Juanli Li, Xu Wang, Mengmeng Liang, Amanda Nancy Sferruzzi-Perri, Xiaoke Wu, Hongxia Ma, Mats Brännström, Linus Ruijin Shao, Håkan Billig
Molecular human reproduction - 2021 -
Increased uterine androgen receptor protein abundance results in implantation and mitochondrial defects in pregnant rats with hyperandrogenism and insulin
resistance.
Yuehui Zhang, Min Hu, Fan Yang, Yizhuo Zhang, Shuting Ma, Dongqi Zhang, Xu Wang, Amanda Nancy Sferruzzi-Perri, Xiaoke Wu, Mats Brännström, Linus Ruijin Shao, Håkan Billig
Journal of molecular medicine (Berlin, Germany) - 2021 -
Long-term androgen-induced nonalcoholic fatty liver disease in a polycystic ovary syndrome mouse model is related to mitochondrial
dysfunction
P. Cui, J. M. Shi, T. Ma, L. Rao, X. Y. Tong, W. Hu, X. Q. Xu, F. F. Zhang, X. Li, Håkan Billig, L. R. Shao, Y. Feng
Reproductive and Developmental Medicine - 2021 -
Long-term androgen excess induces insulin resistance and non-alcoholic fatty liver disease in PCOS-like
rats.
Peng Cui, Wei Hu, Tong Ma, Min Hu, Xiaoyu Tong, Feifei Zhang, Jiemei Shi, Xiaoqing Xu, Xin Li, Linus Ruijin Shao, Håkan Billig, Yi Feng
The Journal of steroid biochemistry and molecular biology - 2021 -
Alterations of endometrial epithelial-mesenchymal transition and MAPK signaling components in women with PCOS are partially modulated by metformin in
vitro.
Min Hu, Yuehui Zhang, Xin Li, Peng Cui, Juan Li, Mats Brännström, Linus Ruijin Shao, Håkan Billig
Molecular human reproduction - 2020 -
Hyperandrogenism and insulin resistance modulate gravid uterine and placental ferroptosis in PCOS-like
rats.
Yuehui Zhang, Min Hu, Wenyan Jia, Guoqi Liu, Jiao Zhang, Bing Wang, Juan Li, Peng Cui, Xin Li, Susanne Lager, Amanda N Sferruzzi-Perri, Yanhua Han, Songjiang Liu, Xiaoke Wu, Mats Brännström, Linus Ruijin Shao, Håkan Billig
The Journal of endocrinology - 2020 -
Uterine glycolytic enzyme expression is affected by knockout of different estrogen receptor
subtypes.
Min Hu, Yuehui Zhang, Emil Egecioglu, Xin Li, Linus Ruijin Shao, Håkan Billig
Biomedical reports - 2019 -
Hyperandrogenism and insulin resistance-induced fetal loss: evidence for placental mitochondrial abnormalities and elevated ROS production in pregnant rats that mimic the clinical features of
PCOS.
Yuehui Zhang, Wei Zhao, Hongfei Xu, Min Hu, Xiaozhu Guo, Wenyan Jia, Guoqi Liu, Juan Li, Peng Cui, Susanne Lager, Amanda Nancy Sferruzzi-Perri, Wei Li, Xiao-Ke Wu, Yanhua Han, Mats Brännström, Linus Ruijin Shao, Håkan Billig
The Journal of physiology - 2019 -
Perturbed ovarian and uterine glucocorticoid receptor signaling accompanies the balanced regulation of mitochondrial function and NFκB-mediated inflammation under conditions of hyperandrogenism and insulin
resistance.
Min Hu, Yuehui Zhang, Xiaozhu Guo, Wenyan Jia, Guoqi Liu, Jiao Zhang, Peng Cui, Juan Li, Wei Li, Xiaoke Wu, Hongxia Ma, Mats Brännström, Linus Ruijin Shao, Håkan Billig
Life sciences - 2019 -
Hyperandrogenism and insulin resistance induce gravid uterine defects in association with mitochondrial dysfunction and aberrant ROS
production.
Min Hu, Yuehui Zhang, Xiaozhu Guo, Wenyan Jia, Guoqi Liu, Jiao Zhang, Juan Li, Peng Cui, Amanda Nancy Sferruzzi-Perri, Yanhua Han, Xiaoke Wu, Hongxia Ma, Mats Brännström, Linus Ruijin Shao, Håkan Billig
American journal of physiology. Endocrinology and metabolism - 2019 -
Differential Expression Patterns of Glycolytic Enzymes and Mitochondria-Dependent Apoptosis in PCOS Patients with Endometrial Hyperplasia, an Early Hallmark of Endometrial Cancer, In Vivo and the Impact of Metformin In
Vitro.
Tao Wang, Jiao Zhang, Min Hu, Yuehui Zhang, Peng Cui, Xin Li, Juan Li, Edvin Vestin, Mats Brännström, Linus Ruijin Shao, Håkan Billig
International journal of biological sciences - 2019 -
Hyperandrogenism and insulin resistance contribute to hepatic steatosis and inflammation in female rat
liver.
Yuehui Zhang, Fanci Meng, Xiaoyan Sun, Xue Sun, Min Hu, Peng Cui, Edvin Vestin, Xin Li, Wei Li, Xiao-Ke Wu, John-Olov Jansson, Linus Ruijin Shao, Håkan Billig
Oncotarget - 2018 -
Endometrial progesterone receptor isoforms in women with polycystic ovary
syndrome
Min Hu, Juan Li, Yuehui Zhang, Xin Li, Mats Brännström, Linus Ruijin Shao, Håkan Billig
American Journal of Translational Research - 2018 -
Uterine progesterone signaling is a target for metformin therapy in PCOS-like
rats.
Min Hu, Yuehui Zhang, Jiaxing Feng, Xue Xu, Jiao Zhang, Wei Zhao, Xiaozhu Guo, Juan Li, Edvin Vestin, Peng Cui, Xin Li, Xiao-Ke Wu, Mats Brännström, Linus Ruijin Shao, Håkan Billig
The Journal of endocrinology - 2018 -
Metformin Ameliorates Uterine Defects in a Rat Model of Polycystic Ovary
Syndrome.
Yuehui Zhang, Min Hu, Fanci Meng, Xiaoyan Sun, Hongfei Xu, Jiao Zhang, Peng Cui, Njomeza Morina, Xin Li, Wei Li, Xiao-Ke Wu, Mats Brännström, Linus Ruijin Shao, Håkan Billig
EBioMedicine - 2017 -
Maternal testosterone and placental function: Effect of electroacupuncture on placental expression of angiogenic markers and fetal
growth
R. Fornes, M. Hu, M. Maliqueo, Milana Kokosar, Anna Benrick, D. Carr, Håkan Billig, T. Jansson, L. Manni, E. Stener-Victorin
Molecular and Cellular Endocrinology - 2016 -
Molecular characterization of insulin resistance and glycolytic metabolism in the rat
uterus.
Yuehui Zhang, Xue Sun, Xiaoyan Sun, Fanci Meng, Min Hu, Xin Li, Wei Li, Xiao-Ke Wu, Mats Brännström, Linus Ruijin Shao, Håkan Billig
Scientific reports - 2016 -
Quantitative analysis of hormones and inflammatory cytokines in Chlamydia trachomatis-infected women with tubal ectopic pregnancy and early intrauterine
pregnancy
Linus Ruijin Shao, Yi Feng, S. Zou, Xin Li, P. Cui, Håkan Billig
Data in Brief - 2016 -
Regulation of androgen receptor expression alters AMPK phosphorylation in the endometrium: In Vivo and In Vitro studies in women with polycystic ovary
syndrome
Xin Li, Bano Pishdari, P. Cui, Min Hu, H.P. Yang, Y.R. Guo, H.Y. Jiang, Yi Feng, Håkan Billig, Linus Ruijin Shao
International Journal of Biological Sciences - 2015 -
Lack of cyclical fluctuations of endometrial GLUT4 expression in women with polycystic ovary syndrome: Evidence for direct regulation of GLUT4 by steroid
hormones
Peng Cui, Xin Li, Xiaoqin Wang, Yi Feng, Jin-Fang Lin, Håkan Billig, Linus Ruijin Shao
BBA Clinical - 2015 -
Reversing the reduced level of endometrial GLUT4 expression in polycystic ovary syndrome: a mechanistic study of metformin
action.
Xin Li, Peng Cui, Hong-Yuan Jiang, Yan-Rong Guo, Bano Pishdari, Min Hu, Yi Feng, Håkan Billig, Linus Ruijin Shao
American journal of translational research - 2015 -
Progesterone-mediated effects on gene expression and oocyte-cumulus complex transport in the mouse fallopian
tube.
Anna Bylander, Lina-Maria Gunnarsson, Linus Ruijin Shao, Håkan Billig, D. G. Joakim Larsson
Reproductive biology and endocrinology : RB&E - 2015 -
The regulation of nitric oxide synthase isoform expression in mouse and human fallopian tubes: Potential insights for ectopic
pregnancy
Junting Hu, S. Ma, S. Zou, X. Li, P. Cui, Birgitta Weijdegård, G. Wu, Linus Ruijin Shao, Håkan Billig, Yi Feng
International Journal of Molecular Sciences - 2015 -
Promising clinical practices of metformin in women with PCOS and early-stage endometrial
cancer
Linus Ruijin Shao, X. Li, Håkan Billig
BBA Clinical - 2014 -
The onset of human ectopic pregnancy demonstrates a differential expression of miRNAs and their cognate targets in the Fallopian
tube
Yi Feng, S. Zou, Birgitta Weijdegård, J. Chen, Q. Cong, Julia Fernandez-Rodriguez, L. Wang, Håkan Billig, Linus Ruijin Shao
International Journal of Clinical and Experimental Pathology - 2014 -
Endometrial progesterone resistance and
PCOS
Xin Li, Yi Feng, Jin-Fang Lin, Håkan Billig, Linus Ruijin Shao
Journal of Biomedical Science. 2014 Jan 09;21(1):2 - 2014 -
Pregnancy after allogeneic uterus transplantation in the rat: perinatal outcome and growth
trajectory.
César Diaz-Garcia, Liza Johannesson, Linus Ruijin Shao, Håkan Billig, Mats Brännström
Fertility and sterility - 2014 -
The elusive and controversial roles of estrogen and progesterone receptors in human
endometriosis
Linus Ruijin Shao, S. Cao, Xiaoyang Wang, Yi Feng, Håkan Billig
American Journal of Translational Research - 2014 -
Direct effects of metformin in the endometrium: a hypothetical mechanism for the treatment of women with PCOS and endometrial
carcinoma
Linus Ruijin Shao, Xin Li, Yi Feng, Jin-Fang Lin, Håkan Billig
Journal of Experimental & Clinical Cancer Research - 2014 -
Burnout is associated with elevated prolactin levels in men but not in
women
Anna-Karin Lennartsson, Håkan Billig, Ingibjörg H Jonsdottir
Journal of Psychosomatic Research - 2014 -
Combination of Diane-35 and Metformin to Treat Early Endometrial Carcinoma in PCOS Women with Insulin
Resistance
Xin Li, Y. R. Guo, J. F. Lin, Yi Feng, Håkan Billig, Linus Ruijin Shao
Journal of Cancer - 2014 -
The inflammatory regulation of tubal β-catenin expression in human ectopic pregnancy: is it too early to propose a cause-and-effect
relationship?
Linus Ruijin Shao, Yi Feng, S. Zou, Xin Li, Håkan Billig
Human reproduction (Oxford, England) - 2013 -
Toward understanding Chlamydia infection-induced infertility caused by dysfunctional
oviducts.
Linus Ruijin Shao, Junting Hu, Håkan Billig
The Journal of infectious diseases - 2013 -
Linking DNA methylation to the onset of human tubal ectopic
pregnancy.
Lei Wang, Yi Feng, Shien Zou, Mats Brännström, Lin He, Håkan Billig, Linus Ruijin Shao
American journal of translational research - 2013 -
Aberrant alteration of vascular endothelial growth factor-family signaling in human tubal ectopic pregnancy: what is known and
unknown?
Linus Ruijin Shao, Junting Hu, Yi Feng, Håkan Billig
International Journal of Clinical and Experimental Pathology - 2013 -
The classical progesterone receptor mediates the rapid reduction of fallopian tube ciliary beat frequency by
progesterone.
Anna Bylander, Karin Lind, Mattias Goksör, Håkan Billig, D. G. Joakim Larsson
Reproductive biology and endocrinology : RB&E - 2013 -
Comparison of the diagnostic values of circulating steroid hormones, VEGF-A, PIGF, and ADAM12 in women with ectopic
pregnancy.
Shien Zou, Xin Li, Yi Feng, Shan Sun, Jin Li, Emil Egecioglu, Håkan Billig, Linus Ruijin Shao
Journal of translational medicine - 2013 -
Electrical vs Manual Acupuncture Stimulation in a Rat Model of Polycystic Ovary Syndrome: Different Effects on Muscle and Fat Tissue Insulin
Signaling
Julia Johansson, Louise Mannerås Holm, Linus Ruijin Shao, AnneLiese Magnusson-Olsson, Malin Lönn, Håkan Billig, Elisabet Stener-Victorin
Plos One - 2013 -
Revealing the Hidden Mechanisms of Smoke-Induced Fallopian Tubal
Implantation.
Linus Ruijin Shao, Shien Zou, Xiaoqin Wang, Yi Feng, Mats Brännström, Elisabet Stener-Victorin, Håkan Billig
Biology of reproduction - 2012 -
The role of estrogen in the pathophysiology of tubal ectopic
pregnancy
Linus Ruijin Shao, Yi Feng, S. E. Zou, Birgitta Weijdegård, G. C. Wu, Mats Brännström, Håkan Billig
American Journal of Translational Research - 2012 -
Coordinate regulation of heterogeneous nuclear ribonucleoprotein dynamics by steroid hormones in the human Fallopian tube and endometrium in vivo and in
vitro.
Linus Ruijin Shao, Xiaoqin Wang, Birgitta Weijdegård, Anders Norström, Julia Fernandez-Rodriguez, Mats Brännström, Håkan Billig
American journal of physiology. Endocrinology and metabolism - 2012 -
From mice to women and back again: Causalities and clues for Chlamydia-induced tubal ectopic
pregnancy.
Linus Ruijin Shao, Xiaoqin Wang, Wei Wang, Elisabet Stener-Victorin, Carina Mallard, Mats Brännström, Håkan Billig
Fertility and sterility - 2012 -
Sex steroid levels temporarily increase in response to acute psychosocial stress in healthy men and
women
Anna-Karin Lennartsson, M. M. Kushnir, Jonas Bergquist, Håkan Billig, Ingibjörg H Jonsdottir
International Journal of Psychophysiology - 2012 -
Electrical and manual acupuncture stimulation affect oestrous cyclicity and neuroendocrine function in an 5α-dihydrotestosterone-induced rat polycystic ovary syndrome
model.
Yi Feng, Julia Johansson, Louise Mannerås Holm, Linus Ruijin Shao, Håkan Billig, Elisabet Stener-Victorin
Experimental physiology - 2012 -
A common variant near the PRL gene is associated with increased adiposity in
males
Louise Nilsson, Anders Olsson, Bo Isomaa, Leif Groop, Håkan Billig, Charlotte Ling
Molecular Genetics and Metabolism - 2011 -
Effects of androgen and leptin on behavioral and cellular responses in female
rats.
Yi Feng, Linus Ruijin Shao, Birgitta Weijdegård, Tienpei Wang, Julia Johansson, Shan Sun, Wei Wang, Emil Egecioglu, Håkan Billig, Elisabet Stener-Victorin
Hormones and behavior - 2011 -
Distinct expression pattern of Dicer1 correlates with ovarian-derived steroid hormone receptor expression in human Fallopian tubes during ovulation and the midsecretory
phase.
Linus Ruijin Shao, Anders Norström, Birgitta Weijdegård, Emil Egecioglu, Julia Fernandez-Rodriguez, Yi Feng, Elisabet Stener-Victorin, Mats Brännström, Håkan Billig
The Journal of clinical endocrinology and metabolism - 2011 -
Rapid effects of progesterone on ciliary beat frequency in the mouse fallopian
tube.
Anna Bylander, Magdalena Nutu, Rikard Wellander, Mattias Goksör, Håkan Billig, D. G. Joakim Larsson
Reproductive biology and endocrinology : RB&E - 2010 -
Spatiotemporal expression of androgen receptors in the female rat brain during the oestrous cycle and the impact of exogenous androgen administration: a comparison with gonadally intact
males.
Yi Feng, Birgitta Weijdegård, Tienpei Wang, Emil Egecioglu, Julia Fernandez-Rodriguez, Ilpo Huhtaniemi, Elisabet Stener-Victorin, Håkan Billig, Linus Ruijin Shao
Molecular and cellular endocrinology - 2010 -
Nitric oxide synthases and tubal ectopic pregnancies induced by Chlamydia infection: basic and clinical
insights.
Linus Ruijin Shao, Sean X Zhang, Birgitta Weijdegård, Shien Zou, Emil Egecioglu, Anders Norström, Mats Brännström, Håkan Billig
Molecular human reproduction - 2010 -
Intense electroacupuncture normalizes insulin sensitivity, increases muscle GLUT4 content, and improves lipid profile in a rat model of polycystic ovary
syndrome.
Julia Johansson, Yi Feng, Linus Ruijin Shao, Malin Lönn, Håkan Billig, Elisabet Stener-Victorin
American journal of physiology. Endocrinology and metabolism - 2010 -
Transcriptional effects of progesterone receptor antagonist in rat granulosa
cells.
P. Anders Friberg, D. G. Joakim Larsson, Håkan Billig
Molecular and cellular endocrinology - 2010 -
Distribution and hormonal regulation of membrane progesterone receptors beta and gamma in ciliated epithelial cells of mouse and human fallopian
tubes.
Magdalena Nutu, Birgitta Weijdegård, Peter Thomas, Ann Thurin-Kjellberg, Håkan Billig, D. G. Joakim Larsson
Reproductive biology and endocrinology : RB&E - 2009 -
Hypothalamic neuroendocrine functions in rats with dihydrotestosterone-induced polycystic ovary syndrome: effects of low-frequency
electro-acupuncture.
Yi Feng, Julia Johansson, Linus Ruijin Shao, Louise Mannerås, Julia Fernandez-Rodriguez, Håkan Billig, Elisabet Stener-Victorin
PloS one - 2009 -
[The Swedish Research Council welcomes the debate on openness and
competition].
Håkan Billig, Carl Jacobsson
Läkartidningen - 2009 -
Prolactin suppresses malonyl-CoA concentration in human adipose
tissue.
Louise Nilsson, C Roepstorff, B Kiens, Håkan Billig, C Ling
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme - 2009 -
Clomiphene citrate causes aberrant tubal apoptosis and estrogen receptor activation in rat fallopian tube: implications for tubal ectopic
pregnancy.
Linus Ruijin Shao, Magdalena Nutu, Birgitta Weijdegård, Emil Egecioglu, Julia Fernandez-Rodriguez, Linda Karlsson-Lindahl, Kristina Gemzell-Danielsson, Christina Bergh, Håkan Billig
Biology of reproduction - 2009 -
Down-Regulation of Cilia-Localized IL-6R{alpha} by 17{beta}-Estradiol in Mouse and Human Fallopian
Tubes.
Linus Ruijin Shao, Magdalena Nutu, Linda Karlsson-Lindahl, Anna Benrick, Birgitta Weijdegård, Susanne Lager, Emil Egecioglu, Julia Fernandez-Rodriguez, Christina Gemzell-Danielsson, Claes Ohlsson, John-Olov Jansson, Håkan Billig
American journal of physiology. Cell physiology - 2009 -
Dominant role of nuclear progesterone receptor in the control of rat periovulatory granulosa cell
apoptosis.
P. Anders Friberg, D. G. Joakim Larsson, Håkan Billig
Biology of reproduction - 2009 -
Differences in prolactin receptor (PRLR) in mouse and human fallopian tubes: evidence for multiple regulatory mechanisms controlling PRLR isoform expression in
mice.
Linus Ruijin Shao, Magdalena Nutu, Birgitta Weijdegård, Emil Egecioglu, Julia Fernandez-Rodriguez, Estelle Tallet, Vincent Goffin, Charlotte Ling, Håkan Billig
Biology of reproduction - 2008 -
Membrane progesterone receptors - Expression and regulation in the human and mouse fallopian tube. 41st Annual Meeting of the Society-for-the-study-of-Reproduction, May 27-30, 2008, Kona,
HI.
Magdalena Nutu, Linus Ruijin Shao, Birgitta Weijdegård, Håkan Billig, D. G. Joakim Larsson
Proceedings in Biology of Reproduction, Special Issue: Sp. Iss. SI - 2008 -
Nuclear progesterone-mediated regulation of apopotosis in rat periovoluatory granulose cells. 41st Annual Meeting of the Society-for-the-Study-of-Reproduction, May 27-30, 2008, Kona,
HI.
P. Anders Friberg, D. G. Joakim Larsson, Håkan Billig
Proceedings in Biology of Reproduction, Special Issue: Sp: Iss. SI - 2008 -
Estrogen-induced upregulation of AR expression and enhancement of AR nuclear translocation in mouse fallopian tubes in
vivo.
Linus Ruijin Shao, Karin Ljungström, Birgitta Weijdegård, Emil Egecioglu, Julia Fernandez-Rodriguez, Fu-Ping Zhang, Ann Thurin-Kjellberg, Christina Bergh, Håkan Billig
American journal of physiology. Endocrinology and metabolism - 2007 -
Ciliated epithelial-specific and regional-specific expression and regulation of the estrogen receptor-beta2 in the fallopian tubes of immature rats: a possible mechanism for estrogen-mediated transport process in
vivo
Linus Ruijin Shao, Birgitta Weijdegård, Julia Fernandez-Rodriguez, Emil Egecioglu, Changlian Zhu, Niklas Andersson, Ann Thurin-Kjellberg, Christina Bergh, Håkan Billig
American journal of physiology - 2007 -
Dynamic regulation of estrogen receptor-alpha isoform expression in the mouse fallopian tube: mechanistic insight into estrogen-dependent production and secretion of insulin-like growth
factors.
Linus Ruijin Shao, Emil Egecioglu, Birgitta Weijdegård, John J Kopchick, Julia Fernandez-Rodriguez, Niklas Andersson, Håkan Billig
American journal of physiology. Endocrinology and metabolism - 2007 -
Apoptotic effects of a progesterone receptor antagonist on rat granulosa cells are not mediated via reduced protein
isoprenylation.
P. Anders Friberg, D. G. Joakim Larsson, Emilia Rung, Håkan Billig
Molecular reproduction and development - 2007 -
Membrane progesterone receptor gamma: tissue distribution and expression in ciliated cells in the fallopian
tube.
Magdalena Nutu, Birgitta Weijdegård, Peter Thomas, Christina Bergh, Ann Thurin-Kjellberg, Yefei Pang, Håkan Billig, D. G. Joakim Larsson
Molecular reproduction and development - 2007 -
Nuclear progesterone receptor A and B isoforms in mouse fallopian tube and uterus: implications for expression, regulation, and cellular
function
Linus Ruijin Shao, Birgitta Weijdegård, Karin Ljungström, P. Anders Friberg, Changlian Zhu, Xiaoyang Wang, Yihong Zhu, Julia Fernandez-Rodriguez, Emil Egecioglu, Emilia Rung, Håkan Billig
American journal of physiology - 2006 -
Estrogen-Induced Up-Regulation of Androgen Receptor (AR) Expression and Enhancement of AR Nuclear Translocation in Mouse Fallopian Tubes in
vivo
Linus Ruijin Shao, Karin Ljungström, Birgitta Weijdegård, Emil Egecioglu, Julia Fernandez-Rodriguez, Fu-Ping Zhang, Ann Thurin-Kjellberg, Håkan Billig
Am J Physiol Endocrinol Metab. - 2006 -
Developmental and hormonal regulation of progesterone receptor A-form expression in female mouse lung in vivo: interaction with glucocorticoid
receptors
Linus Ruijin Shao, Emil Egecioglu, Birgitta Weijdegård, Karin Ljungström, C. Ling, Julia Fernandez-Rodriguez, Håkan Billig
The Journal of endocrinology - 2006 -
Depletion of substrates for protein prenylation increases apoptosis in human periovulatory granulosa
cells
Emilia Rung, P. Anders Friberg, Christina Bergh, Håkan Billig
Molecular reproduction and development - 2006 -
Induction of apoptosis increases SUMO-1 protein expression and conjugation in mouse periovulatory granulosa cells in
vitro
Linus Ruijin Shao, Emilia Rung, Birgitta Weijdegård, Håkan Billig
Molecular reproduction and development - 2006 -
Prolactin and growth hormone regulate adiponectin secretion and receptor expression in adipose
tissue
Louise Nilsson, Nadine Binart, Mohammad Bohlooly-Yeganeh, Margareta Bramnert, Emil Egecioglu, Jon Kindblom, Paul Kelly, John J Kopchick, Christopher Ormandy, Charlotte Ling, Håkan Billig
Biochemical and Biophysical Research Communications - 2005 -
Progesterone-receptor antagonists and statins decrease de novo cholesterol synthesis and increase apoptosis in rat and human periovulatory granulosa cells in
vitro
Emilia Rung, P. Anders Friberg, Linus Ruijin Shao, D. G. Joakim Larsson, Eva Ch. Nielsen, Per-Arne Svensson, Björn Carlsson, Lena M S Carlsson, Håkan Billig
Biology of reproduction - 2005 -
Progesterone membrane receptors - regulation in the ovary of the
rat.
Magdalena Nutu, P. Thomas, Håkan Billig, D. G. Joakim Larsson
Proceedings in: Steroids. Poster presentation at the FASEB conference on "Steroid Hormone Receptors: Integration of Plasma Membrane and Nuclear-Initiated Signaling in the Hormone Action", July 31 - Aug 5, 2004, Tucson, Arizona, USA - 2005 -
Increase of SUMO-1 expression in response to hypoxia: direct interaction with HIF-1alpha in adult mouse brain and heart in
vivo
Linus Ruijin Shao, F. P. Zhang, Fei Tian, P. Anders Friberg, Xiaoyang Wang, Helen Sjöland, Håkan Billig
FEBS letters - 2004 -
Neonatal losartan treatment suppresses renal expression of molecules involved in cell-cell and cell-matrix
interactions
Yun Chen, Daina Lasaitiene, Britt G. Gabrielsson, Lena M S Carlsson, Håkan Billig, Björn Carlsson, N. Marcussen, X. F. Sun, Peter Friberg
Journal of the American Society of Nephrology - 2004 -
Inhibition of small ubiquitin-related modifier-1 expression by luteinizing hormone receptor stimulation is linked to induction of progesterone receptor during ovulation in mouse granulosa
cells
Linus Ruijin Shao, F. P. Zhang, Emilia Rung, JJ Palvimo, I Huhtaniemi, Håkan Billig
ENDOCRINOLOGY - 2004 -
111In-labelled octreotide binding by the somatostatin receptor subtype 2 in neuroendocrine
tumours.
S H Hashemi, S-A Benjegård, Håkan Ahlman, Bo Wängberg, Eva Forssell-Aronsson, Håkan Billig, Ola Nilsson
The British journal of surgery - 2003 -
Copper induces the expression of cholesterogenic genes in human
macrophages.
Per-Arne Svensson, Mikael C. O. Englund, Emilia Markström, Bertil Ohlsson, Margareta Jernås, Håkan Billig, Jarl S Torgerson, Olov Wiklund, Lena M S Carlsson, Björn Carlsson
Atherosclerosis - 2003 -
Identification of Functional Prolactin (PRL) Receptor Gene Expression: PRL Inhibits Lipoprotein Lipase Activity in Human White Adipose
Tissue
Charlotte Ling, Louise Svensson, Birgitta Odén, Birgitta Weijdegård, Barbro Edén, Staffan Edén, Håkan Billig
The Journal of Clinical Endocrinology & Metabolism - 2003 -
Expression of progesterone receptor (PR) A and B isoforms in mouse granulosa cells: stage-dependent PR-mediated regulation of apoptosis and cell
proliferation.
Linus Ruijin Shao, Emilia Markström, P. Anders Friberg, Maria Johansson, Håkan Billig
Biology of reproduction - 2003 -
Expression of scavenger receptor class B type I in gallbladder columnar
epithelium.
Magnus S.C. Johnson, Per-Arne Svensson, Jan Borén, Håkan Billig, Lena M S Carlsson, Björn Carlsson
Journal of gastroenterology and hepatology - 2002 -
The effects of physical activity and estrogen treatment on rat fast and slow skeletal muscles following
ovariectomy.
Fawzi Kadi, Camilla Karlsson, Britt Larsson, Jennie Eriksson, Maria Larval, Håkan Billig, Ingibjörg H Jonsdottir
Journal of muscle research and cell motility - 2002 -
Follicular development and
apoptosis.
Håkan Billig, Emilia Markström, Eva Ch Svensson, Linus Ruijin Shao, P. Anders Friberg
Ernst Schering Research Foundation workshop - 2002 -
Survival factors regulating ovarian apoptosis -- dependence on follicle
differentiation.
Emilia Markström, Eva Ch Svensson, Linus Ruijin Shao, Bodil Svanberg, Håkan Billig
Reproduction (Cambridge, England) - 2002 -
Progesterone receptor antagonists Org 31710 and RU 486 increase apoptosis in human periovulatory granulosa
cells.
Eva Ch Svensson, Emilia Markström, Linus Ruijin Shao, Madeleine Andersson, Håkan Billig
Fertility and sterility - 2001 -
Progesterone receptor-mediated inhibition of apoptosis in granulosa cells isolated from rats treated with human chorionic
gonadotropin.
Eva Ch Svensson, Emilia Markström, M Andersson, Håkan Billig
Biology of reproduction - 2000 -
Comparative studies on the expression of somatostatin receptor subtypes, outcome of octreotide scintigraphy and response to octreotide treatment in patients with carcinoid
tumours.
Ola Nilsson, Lars Kölby, Bo Wängberg, A Wigander, Håkan Billig, L William-Olsson, M Fjälling, Eva Forssell-Aronsson, Håkan Ahlman
British journal of cancer - 1998 -
Expression of functional leptin receptors in the human
ovary
C Karlsson, K Lindell, E Svensson, Christina Bergh, P Lind, Håkan Billig, LM Carlsson, B Carlsson
Journal of Clinical Endocrinology and Metabolism - 1997 -
Expression of functional growth hormone receptors in human granulosa
cells
Bengt Carlsson, Christina Bergh, J Bentham, Jan-Henrik Stjerndahl, MR Norrman, Håkan Billig, P Roos, Torbjörn Hillensjö
Human Reproduction - 1992 -
Effects of insulin-like growth factor I and growth hormone in cultured human granulosa
cells
Christina Bergh, B Carlsson, Jan-Henrik Stjerndahl, Håkan Olausson, Håkan Billig, Torbjörn Hillensjö
Annals of the New York Academy of Sciences - 1991