Claes Ohlsson

• Body weight reduction by increased weight loading in mice is associated with sensory signaling in the dorsal horn of the lumbar spinal cord.

  Fredrik Anesten, Jovana Zlatkovic, Claes Ohlsson, Line Sofie Löken, Daniel Hägg, John-Olov Jansson
  Neuroscience - 2025
• IL-6 decodes sex and diet-dependent circadian and metabolic rhythms

  Antia Gonzalez-Vila, Ali Mohammad Ibrahim-Alasoufi, Maria Luengo-Mateos, Victor Pardo-Garcia, Alejandro Diaz-Lopez, Belen Fernandez-Rodriguez, Matti Poutanen, Claes Ohlsson, Manuel Tena-Sempere, Carlos Dieguez-Gonzalez, Maria del Carmen Garcia-Garcia, Olga Barca-Mayo
  MOLECULAR METABOLISM - 2025
• Membrane-initiated estrogen receptor-α signaling in osteoblasts is crucial for normal regulation of the cortical bone in female mice

  Yiwen Jiang, Karin Horkeby, Petra Henning, Jianyao Wu, Karin H. Nilsson, Lina Lawenius, Sofia Moverare-Skrtic, Priti Gupta, Cecilia Engdahl, Antti Koskela, Juha Tuukkanen, Lei Li, Claes Ohlsson, Marie K Lagerquist
  BONE RESEARCH - 2025
• Polygenic prediction of body mass index and obesity through the life course and across ancestries.

  Roelof A J Smit, Kaitlin H Wade, Qin Hui, Joshua D Arias, Xianyong Yin, Malene R Christiansen, Loic Yengo, Michael H Preuss, Mariam Nakabuye, Ghislain Rocheleau, Sarah E Graham, Victoria L Buchanan, Geetha Chittoor, Marielisa Graff, Marta Guindo-Martínez, Yingchang Lu, Eirini Marouli, Saori Sakaue, Cassandra N Spracklen, Sailaja Vedantam, Emma P Wilson, Shyh-Huei Chen, Teresa Ferreira, Yingjie Ji, Tugce Karaderi, Kreete Lüll, Moara Machado, Deborah E Malden, Carolina Medina-Gomez, Amy Moore, Sina Rüeger, Masato Akiyama, Matthew A Allison, Marcus Alvarez, Mette K Andersen, Vivek Appadurai, Liubov Arbeeva, Eric Bartell, Seema Bhaskar, Lawrence F Bielak, Joshua C Bis, Sailalitha Bollepalli, Jette Bork-Jensen, Jonathan P Bradfield, Yuki Bradford, Caroline Brandl, Peter S Braund, Jennifer A Brody, Ulrich Broeckel, Kristoffer S Burgdorf, Brian E Cade, Qiuyin Cai, Silvia Camarda, Archie Campbell, Marisa Cañadas-Garre, Jin-Fang Chai, Alessandra Chesi, Seung Hoan Choi, Paraskevi Christofidou, Christian Couture, Gabriel Cuellar-Partida, Rebecca Danning, Frauke Degenhardt, Graciela E Delgado, Alessandro Delitala, Ayşe Demirkan, Xuan Deng, Alexander Dietl, Maria Dimitriou, Latchezar Dimitrov, Rajkumar Dorajoo, Fabian Eichelmann, Anders U Eliasen, Jorgen E Engmann, Michael R Erdos, Zammy Fairhurst-Hunter, Aliki-Eleni Farmaki, Jessica D Faul, Juan-Carlos Fernandez-Lopez, Lukas Forer, Mirjam Frank, Sandra Freitag-Wolf, Lars G Fritsche, Christian Fuchsberger, Tessel E Galesloot, Yan Gao, Frank Geller, Olga Giannakopoulou, Franco Giulianini, Anette P Gjesing, Anuj Goel, Scott D Gordon, Mathias Gorski, Jakob Grove, Xiuqing Guo, Stefan Gustafsson, Jeffrey Haessler, Thomas F Hansen, Aki S Havulinna, Simon J Haworth, Nancy Heard-Costa, Daiane Hemerich, Heather M Highland, George Hindy, Yuk-Lam Ho, Edith Hofer, Elizabeth Holliday, Katrin Horn, Whitney E Hornsby, Jouke-Jan Hottenga, Hongyan Huang, Jie Huang, Alicia Huerta-Chagoya, Shaofeng Huo, Mi Yeong Hwang, Chii-Min Hwu, Hiroyuki Iha, Daisuke D Ikeda, Masato Isono, Anne U Jackson, Iris E Jansen, Yunxuan Jiang, Ingegerd Johansson, Anna Jonsson, Torben Jørgensen, Ioanna P Kalafati, Masahiro Kanai, Stavroula Kanoni, Line L Kårhus, Anuradhani Kasturiratne, Tomohiro Katsuya, Takahisa Kawaguchi, Rachel L Kember, Katherine A Kentistou, Daeeun Kim, Han-Na Kim, Young Jin Kim, Marcus E Kleber, Maria J Knol, Azra Kurbasic, Marie Lauzon, Phuong Le, Rodney Lea, Jong-Young Lee, Wen-Jane Lee, Hampton L Leonard, Hengtong Li, Shengchao A Li, Xiaohui Li, Xiaoyin Li, Jingjing Liang, Honghuang Lin, Kuang Lin, Jun Liu, Xueping Liu, Ken Sin Lo, Jirong Long, Laura Lores-Motta, Jian'an Luan, Valeriya Lyssenko, Leo-Pekka Lyytikäinen, Anubha Mahajan, Md Zubbair Malik, Vasiliki Mamakou, Massimo Mangino, Ani Manichaikul, Jonathan Marten, Manuel Mattheisen, Aaron F McDaid, Quanshun Mei, Heike Meiselbach, Tori L Melendez, Yuri Milaneschi, Jason E Miller, Iona Y Millwood, Pashupati P Mishra, Ruth E Mitchell, Line T Møllehave, Nina Mononen, Sören Mucha, Matthias Munz, Juha Mykkänen, Masahiro Nakatochi, Giuseppe Giovanni Nardone, Christopher P Nelson, Maria Nethander, Chu Won Nho, Aneta A Nielsen, Ilja M Nolte, Suraj S Nongmaithem, Raymond Noordam, Ioanna Ntalla, Teresa Nutile, Anita Pandit, Marc Pauper, Eva R B Petersen, Liselotte V Petersen, Francesco Piluso, Ozren Polašek, Alaitz Poveda, Saiju Pyarajan, Laura M Raffield, Hiromi Rakugi, Julia Ramirez, Asif Rasheed, Dennis Raven, Nigel W Rayner, Carlos Riveros, Rebecca Rohde, Daniela Ruggiero, Sanni E Ruotsalainen, Kathleen A Ryan, Maria Sabater-Lleal, Aurora Santin, Richa Saxena, Markus Scholz, Botong Shen, Jingchunzi Shi, Jae Hun Shin, Carlo Sidore, Julia Sidorenko, Xueling Sim, Roderick C Slieker, Albert V Smith, Jennifer A Smith, Laura J Smyth, Lorraine Southam, Valgerdur Steinthorsdottir, Liang Sun, Fumihiko Takeuchi, Kent D Taylor, Bamidele O Tayo, Catherine Tcheandjieu, Natalie Terzikhan, Paola Tesolin, Alexander Teumer, Elizabeth Theusch, Deborah J Thompson, Gudmar Thorleifsson, Paul R H J Timmers, Stella Trompet, Constance Turman, Simona Vaccargiu, Sander W van der Laan, Peter J van der Most, Jan B van Klinken, Jessica van Setten, Shefali S Verma, Niek Verweij, Yogasudha Veturi, Carol A Wang, Chaolong Wang, Jun-Sing Wang, Lihua Wang, Ya Xing Wang, Zhe Wang, Helen R Warren, Wen Bin Wei, Wanqing Wen, William A Wheeler, Ananda R Wickremasinghe, Matthias Wielscher, Bendik S Winsvold, Andrew Wong, Matthias Wuttke, Rui Xia, Ken Yamamoto, Jingyun Yang, Jie Yao, Hannah Young, Noha A Yousri, Lei Yu, Lingyao Zeng, Weihua Zhang, Xinyuan Zhang, Jing-Hua Zhao, Wei Zhao, Wei Zhou, Martina E Zimmermann, Magdalena Zoledziewska, Leen M 't Hart, Linda S Adair, Hieab H H Adams, Carlos A Aguilar-Salinas, Fahd Al-Mulla, Donna K Arnett, Folkert W Asselbergs, Bjørn Olav Åsvold, John Attia, Bernhard Banas, Stefania Bandinelli, Lawrence J Beilin, David A Bennett, Tobias Bergler, Dwaipayan Bharadwaj, Ginevra Biino, Eric Boerwinkle, Carsten A Böger, Judith B Borja, Claude Bouchard, Donald W Bowden, Ivan Brandslund, Ben Brumpton, Julie E Buring, Mark J Caulfield, John C Chambers, Giriraj R Chandak, Stephen J Chanock, Nish Chaturvedi, Yii-Der Ida Chen, Zhengming Chen, Ching-Yu Cheng, Yoon Shin Cho, Kaare Christensen, Ingrid E Christophersen, Marina Ciullo, John W Cole, Francis S Collins, Maria Pina Concas, Richard S Cooper, Miguel Cruz, Francesco Cucca, Michael J Cutler, Scott M Damrauer, Thomas M Dantoft, Gert J de Borst, Eco J C de Geus, Lisette C P G M de Groot, Philip L De Jager, Dominique P V de Kleijn, H Janaka de Silva, George V Dedoussis, Anneke I den Hollander, Shufa Du, Douglas F Easton, Kai-Uwe Eckardt, Petra J M Elders, A Heather Eliassen, Patrick T Ellinor, Sölve Elmståhl, Jeanette Erdmann, Michele K Evans, Diane Fatkin, Bjarke Feenstra, Mary F Feitosa, Luigi Ferrucci, Jose C Florez, Ian Ford, Myriam Fornage, Andre Franke, Paul W Franks, Barry I Freedman, Christian Gieger, Giorgia Girotto, Yvonne M Golightly, Clicerio Gonzalez-Villalpando, Penny Gordon-Larsen, Harald Grallert, Struan F A Grant, Niels Grarup, Lyn Griffiths, Vilmundur Gudnason, Christopher Haiman, Hakon Hakonarson, Torben Hansen, Catharina A Hartman, Andrew T Hattersley, Caroline Hayward, Iris M Heid, Chew-Kiat Heng, Christian Hengstenberg, Karl-Heinz Herzig, Alex W Hewitt, Haretsugu Hishigaki, David M Hougaard, Carel B Hoyng, Paul L Huang, Wei Huang, Wen-Yi Huang, Jennifer E Huffman, Steven C Hunt, Nina Hutri, Kristian Hveem, Elina Hyppönen, William G Iacono, Sahoko Ichihara, M Arfan Ikram, Carmen R Isasi, Marjo-Riitta Jarvelin, Zi-Bing Jin, Karl-Heinz Jöckel, Jost B Jonas, Peter K Joshi, Pekka Jousilahti, J Wouter Jukema, Mika Kähönen, Yoichiro Kamatani, Kui Dong Kang, Jaakko Kaprio, Sharon L R Kardia, Fredrik Karpe, Norihiro Kato, Maryam Kavousi, Frank Kee, Thorsten Kessler, Amit V Khera, Chiea Chuen Khor, Lambertus A L M Kiemeney, Bong-Jo Kim, Eung Kweon Kim, Hyung-Lae Kim, Paulus Kirchhof, Mika Kivimaki, Woon-Puay Koh, Heikki A Koistinen, Alexander Kokkinos, Jaspal S Kooner, Charles Kooperberg, Peter Kovacs, Adriaan Kraaijeveld, Peter Kraft, Ronald M Krauss, Meena Kumari, Zoltan Kutalik, Markku Laakso, Leslie A Lange, Claudia Langenberg, Lenore J Launer, Hyejin Lee, Nanette R Lee, Terho Lehtimäki, Rozenn N Lemaitre, Huaixing Li, Liming Li, Wolfgang Lieb, Xu Lin, Lars Lind, Allan Linneberg, Ching-Ti Liu, Jianjun Liu, Markus Loeffler, Barry London, Fan Lu, Steven A Lubitz, David A Mackey, Patrik K E Magnusson, JoAnn E Manson, Gregory M Marcus, Pedro Marques Vidal, Nicholas G Martin, Winfried März, Fumihiko Matsuda, Mark I McCarthy, Robert W McGarrah, Matt McGue, Amy Jayne McKnight, Sarah E Medland, Dan Mellström, Andres Metspalu, Braxton D Mitchell, Paul Mitchell, Dennis O Mook-Kanamori, Trevor A Mori, Andrew D Morris, Lorelei A Mucci, Patricia B Munroe, Mike A Nalls, Saman Nazarian, Amanda E Nelson, Matt J Neville, Christopher Newton-Cheh, Christopher S Nielsen, Harri Niinikoski, Kjell Nikus, Markus M Nöthen, Adesola Ogunniyi, Claes Ohlsson, Albertine J Oldehinkel, Lorena Orozco, Katja Pahkala, Päivi Pajukanta, Colin N A Palmer, Esteban J Parra, Cristian Pattaro, Oluf Pedersen, Craig E Pennell, Brenda W J H Penninx, Louis Perusse, Annette Peters, Patricia A Peyser, David J Porteous, Danielle Posthuma, Chris Power, Peter P Pramstaller, Michael A Province, Bruce M Psaty, Qibin Qi, Jia Qu, Daniel J Rader, Olli T Raitakari, Loukianos S Rallidis, Dabeeru C Rao, Susan Redline, Dermot F Reilly, Alexander P Reiner, Sang Youl Rhee, Paul M Ridker, Michiel Rienstra, Samuli Ripatti, Marylyn D Ritchie, Fernando Rivadeneira, Dan M Roden, Frits R Rosendaal, Jerome I Rotter, Igor Rudan, Femke Rutters, Seungho Ryu, Charumathi Sabanayagam, Babatunde Salako, Danish Saleheen, Veikko Salomaa, Nilesh J Samani, Dharambir K Sanghera, Naveed Sattar, Börge Schmidt, Helena Schmidt, Reinhold Schmidt, Matthias B Schulze, Heribert Schunkert, Laura J Scott, Rodney J Scott, Peter Sever, Wayne H H Sheu, M Benjamin Shoemaker, Xiao-Ou Shu, Eleanor M Simonsick, Mario Sims, Andrew B Singleton, Moritz F Sinner, J. Gustav Smith, Harold Snieder, Tim D Spector, Beatrice Spedicati, Meir J Stampfer, Klaus J Stark, David P Strachan, Yasuharu Tabara, E Shyong Tai, Hua Tang, Jean-Claude Tardif, Thangavel A Thanaraj, Anke Tönjes, Tiinamaija Tuomi, Jaakko Tuomilehto, Maria-Teresa Tusié-Luna, Rob M van Dam, Pim van der Harst, Nathalie Van der Velde, Cornelia M van Duijn, Natasja M van Schoor, Veronique Vitart, Marie-Claude Vohl, Uwe Völker, Peter Vollenweider, Henry Völzke, Scott Vrieze, Niels H Wacher-Rodarte, Mark Walker, Gurpreet S Wander, Nicholas J Wareham, Richard M Watanabe, Hugh Watkins, David R Weir, Thomas M Werge, Elisabeth Widen, Gonneke Willemsen, Walter C Willett, James F Wilson, Peter W F Wilson, Tien Y Wong, Jeong-Taek Woo, Alan F Wright, Huichun Xu, Chittaranjan S Yajnik, Jian Yang, Mitsuhiro Yokota, Jian-Min Yuan, Eleftheria Zeggini, Babette S Zemel, Wei Zheng, Xiaofeng Zhu, M Carola Zillikens, Alan B Zonderman, John-Anker Zwart, Goncalo R Abecasis, Themistocles L Assimes, Adam Auton, Michael Boehnke, Daniel I Chasman, Tõnu Esko, Kari Stefansson, Guillaume Lettre, Cecilia M Lindgren, Maggie C Y Ng, Christopher J O'Donnell, Unnur Thorsteinsdottir, Peter M Visscher, Robin G Walters, Thomas W Winkler, Andrew R Wood, Panos Deloukas, Timothy M Frayling, Anne E Justice, Tuomas O Kilpeläinen, Adam E Locke, Karen L Mohlke, Kari E North, Yukinori Okada, Cristen J Willer, Kristin L Young, Segun Fatumo, Jeanne M McCaffery, Nicholas J Timpson, Joel N Hirschhorn, Yan V Sun, Sonja I Berndt, Ruth J F Loos
  Nature medicine - 2025
• Body mass index and subsequent fracture risk: a meta-analysis to update FRAX.

  Nicholas C Harvey, Helena Johansson, Eugene V McCloskey, Enwu Liu, Kristina E Åkesson, Fred A Anderson, Rafael Azagra-Ledesma, Cecilie L Bager, Charlotte Beaudart, Heike A Bischoff-Ferrari, Emmanuel Biver, Olivier Bruyère, Jane A Cauley, Jacqueline R Center, Roland Chapurlat, Claus Christiansen, Cyrus Cooper, Carolyn J Crandall, Steven R Cummings, José A P da Silva, Bess Dawson-Hughes, Adolfo Diez-Perez, Alyssa B Dufour, John A Eisman, Petra J M Elders, Serge Ferrari, Yuki Fujita, Saeko Fujiwara, Claus-Christian Glüer, Inbal Goldshtein, David Goltzman, Vilmundur Gudnason, Jill Hall, Didier Hans, Mari Hoff, Rosemary J Hollick, Martijn Huisman, Masayuki Iki, Sophia Ish-Shalom, Graeme Jones, Magnus K Karlsson, Sundeep Khosla, Douglas P Kiel, Woon-Puay Koh, Fjorda Koromani, Mark A Kotowicz, Heikki Kröger, Timothy Kwok, Olivier Lamy, Arnulf Langhammer, Bagher Larijani, Kurt Lippuner, Fiona E A McGuigan, Dan Mellström, Thomas Merlijn, Tuan V Nguyen, Anna Nordström, Peter Nordström, Terence W O'Neill, Barbara Obermayer-Pietsch, Claes Ohlsson, Eric S Orwoll, Julie A Pasco, Fernando Rivadeneira, Berit Schei, Anne-Marie Schott, Eric J Shiroma, Kristin Siggeirsdottir, Eleanor M Simonsick, Elisabeth Sornay-Rendu, Reijo Sund, Karin M A Swart, Pawel Szulc, Junko Tamaki, David J Torgerson, Natasja M van Schoor, Tjeerd P van Staa, Joan Vila, Nicholas J Wareham, Nicole C Wright, Noriko Yoshimura, M Carola Zillikens, Marta Zwart, Liesbeth Vandenput, Mattias Lorentzon, William D Leslie, John A Kanis
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2025
• Female mice with HSD17B1 inactivation show mild hyperandrogenism without notable impact on reproductive function or bone.

  Arttu Junnila, Nataliia Petruk, Hanna Heikelä, Pekka Postila, Janne Hakkarainen, Guillermo Martinez-Nieto, Esperanza Uceda-Rodriguez, Francisco Ruiz-Pino, Manuel Tena-Sempere, Claes Ohlsson, Petra Sipilä, Terhi J Heino, Jorma Määttä, Matti Poutanen
  Endocrinology - 2025
• Growth hormone regulates the stem cell population in the growth plate.

  Nelson Tsz Long Chu, Baoyi Zhou, Jussi O Heinonen, Ostap Dregval, Xin Liu, Dana Trompet, Xin Tian, Phillip T Newton, Lars Sävendahl, Ameya Bendre, Ola Nilsson, Claes Ohlsson, Andrei Chagin
  Proceedings of the National Academy of Sciences of the United States of America - 2025
• Change in Weight Status From Childhood to Young Adulthood and Risk of Adult Coronary Heart Disease.

  Claes Ohlsson, Rebecka Bramsved, Maria Bygdell, Jari Martikainen, Annika Rosengren, Jenny M Kindblom
  JAMA pediatrics - 2025
• Family history of fracture and fracture risk: a meta-analysis to update the FRAX® risk assessment tool

  Eugene V. McCloskey, Helena Johansson, Enwu Liu, Kristina E. Åkesson, Fred A. Anderson, Rafael Azagra-Ledesma, Cecilie L. Bager, Charlotte Beaudart, Heike A. Bischoff-Ferrari, Emmanuel Biver, Olivier Bruyère, Jane A. Cauley, Jacqueline R. Center, Roland Chapurlat, Claus Christiansen, Cyrus Cooper, Carolyn J. Crandall, Steven R. Cummings, José A.P. da Silva, Bess Dawson-Hughes, Adolfo Diez-Perez, Alyssa B. Dufour, John A. Eisman, Petra J.M. Elders, Serge Ferrari, Yuki Fujita, Saeko Fujiwara, Claus Christian Glüer, Inbal Goldshtein, David Goltzman, Vilmundur Gudnason, Jill Hall, Didier Hans, Mari Hoff, Rosemary J. Hollick, Martijn Huisman, Masayuki Iki, Sophia Ish-Shalom, Graeme Jones, Magnus K. Karlsson, Sundeep Khosla, Douglas P. Kiel, Woon Puay Koh, Fjorda Koromani, Mark A. Kotowicz, Heikki Kröger, Timothy Kwok, Olivier Lamy, Arnulf Langhammer, Bagher Larijani, Kurt Lippuner, Dan Mellström, Fiona E.A. McGuigan, Thomas Merlijn, Tuan V. Nguyen, Anna Nordström, Peter Nordström, Terence W. O´Neill, Barbara Obermayer-Pietsch, Claes Ohlsson, Eric S. Orwoll, Julie A. Pasco, Fernando Rivadeneira, Berit Schei, Anne Marie Schott, Eric J. Shiroma, Kristin Siggeirsdottir, Eleanor M. Simonsick, Elisabeth Sornay-Rendu, Reijo Sund, Karin M.A. Swart, Pawel Szulc, Junko Tamaki, David J. Torgerson, Natasja M. van Schoor, Tjeerd P. van Staa, Joan Vila, Nicholas J. Wareham, Nicole C. Wright, Noriko Yoshimura, M. Carola Zillikens, Marta Zwart, Marian Schini, Liesbeth Vandenput, Nicholas C. Harvey, Mattias Lorentzon, William D. Leslie, John A. Kanis
  Osteoporosis International - 2025
• The circulating dihydrotestosterone/testosterone ratio is increased by gut microbial 5α-reductase activity in females

  Claes Ohlsson, Lei Li, Karin Horkeby, Lina Lawenius, Hannah Colldén, Klara Sjögren, Gabriel Baldanzi, Gunnar Engström, Johan Ärnlöv, Marju Orho-Melander, Tove Fall, Louise Grahnemo
  Ebiomedicine - 2025
• Increased weight-bearing load reduces biological body weight while sodium and water balances are unaffected

  Jovana Zlatkovic, Jakob Bellman, Daniel Hägg, Mathilda Magnusson, Claes Ohlsson, Gerald DiBona, Fredrik Anesten, John-Olov Jansson
  PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY - 2025
• Higher Serum Free T4 Is Associated With Increased Risk of Mortality and Cerebrovascular Events in Elderly Men

  Johan Svensson, Claes Ohlsson, Magnus K. Karlsson, Åsa Tivesten, Hans Herlitz, Mattias Lorentzon, Catharina Lewerin, Dan Mellström
  JOURNAL OF THE ENDOCRINE SOCIETY - 2025
• Body mass index during childhood and puberty: associations with blood pressure and hypertension

  Lina Lilja, Maria Bygdell, Jari Martikainen, Huiqi Li, Caroline Schmidt, Göran Bergström, Annika Rosengren, Claes Ohlsson, Jenny Kindblom
  EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY - 2025
• Associations of Serum Testosterone and SHBG With Incident Fractures in Middle-aged to Older Men

  Louise Grahnemo, Ross J. Marriott, Kevin Murray, Lauren T. Tyack, Maria Nethander, Alvin M. Matsumoto, Eric S. Orwoll, Dirk Vanderschueren, Bu B. Yeap, Claes Ohlsson
  Journal of Clinical Endocrinology and Metabolism - 2025
• Tartrate-resistant acid phosphatase augments the bone anabolic response to mechanical loading in male mice

  Bhavik Rathod, Hasmik Jasmine Samvelyan, Suchita Desai, Laura Bock, Nicole Gustafsson, Jianyao Wu, Claes Ohlsson, Per Magnusson, Goeran Andersson, Sara H. Windahl
  JBMR PLUS - 2025
• Increased weight-load improves body composition by reducing fat mass and waist circumference, and by increasing lean mass in participants with obesity: a single-centre randomised controlled trial

  Jakob Bellman, Klaas Westerterp, Loek Wouters, Marit Johannesson, Niklas Lundqvist, Joel Kullberg, Christel Larsson, Mikael Gustafsson, Stefan Pettersson, Jonatan Fridolfsson, Daniel Arvidsson, Mats Börjesson, Dan Curiac, John-Olov Jansson, Per-Anders Jansson, Claes Ohlsson
  BMC MEDICINE - 2025
• Maternal Adiponectin Decreases Placenta Nutrient Transport in Mice.

  Manisha Samad, Benjamin Ulfenborg, Sahar Soleimani Sani, Marco Bauzá-Thorbrügge, Man Mohan Shrestha, Claes Ohlsson, Manuel Maliqueo, Elisabet Stener-Victorin, Ingrid Wernstedt Asterholm, Anna Benrick
  The FASEB Journal - 2025
• The beneficial effects of a probiotic mix on bone and lean mass are dependent on the diet in female mice.

  Claes Ohlsson, Lina Lawenius, Yiwen Jiang, Karin Horkeby, Jianyao Wu, Karin H. Nilsson, Antti Koskela, Juha Tuukkanen, Sofia Movérare-Skrtic, Petra Henning, Klara Sjögren
  Scientific Reports - 2025
• Prenatally androgenized PCOS mice have ovary-independent uterine dysfunction and placental inflammation aggravated by high-fat diet.

  Lena Luyckx, Milena Myllykangas, Ulla Saarela, Nikke Virtanen, Elisa Hurskainen, Audrey Savolainen, Nadja Ollikainen, Anna-Karin Norlén, Claes Ohlsson, Matti Poutanen, Greetje Vande Velde, Riikka K Arffman, Renata Prunskaite-Hyyryläinen, Joris Vriens, Terhi T Piltonen
  Science advances - 2025
• Endogenous sex hormone levels are associated with the revised Framingham Stroke Risk Profile in postmenopausal women: a longitudinal study in a Swedish cohort.

  Kristin Ottarsdottir, Åsa Tivesten, Claes Ohlsson, Ying Li, Margareta Hellgren, Ulf Lindblad, Bledar Daka
  BMC Endocrine Disorders - 2025
• Single-cell profiling of the human endometrium in polycystic ovary syndrome

  Gustaw Eriksson, Congru Li, Tina Gorsek Sparovec, Anja Dekanski, Sara Torstensson, Sanjiv Risal, Claes Ohlsson, Angelica Linden Hirschberg, Sophie Petropoulos, Qiaolin Deng, Elisabet Stener-Victorin
  NATURE MEDICINE - 2025
• Rheumatoid arthritis and subsequent fracture risk: an individual person meta-analysis to update FRAX.

  John A Kanis, Helena Johansson, Eugene V McCloskey, Enwu Liu, Marian Schini, Liesbeth Vandenput, Kristina E Åkesson, Fred A Anderson, Rafael Azagra, Cecilie L Bager, Charlotte Beaudart, Heike A Bischoff-Ferrari, Emmanuel Biver, Olivier Bruyère, Jane A Cauley, Jacqueline R Center, Roland Chapurlat, Claus Christiansen, Cyrus Cooper, Carolyn J Crandall, Steven R Cummings, José A P da Silva, Bess Dawson-Hughes, Adolfo Diez-Perez, Alyssa B Dufour, John A Eisman, Petra J M Elders, Serge Ferrari, Yuki Fujita, Saeko Fujiwara, Claus-Christian Glüer, Inbal Goldshtein, David Goltzman, Vilmundur Gudnason, Jill Hall, Didier Hans, Mari Hoff, Rosemary J Hollick, Martijn Huisman, Masayuki Iki, Sophia Ish-Shalom, Graeme Jones, Magnus K Karlsson, Sundeep Khosla, Douglas P Kiel, Woon-Puay Koh, Fjorda Koromani, Mark A Kotowicz, Heikki Kröger, Timothy Kwok, Olivier Lamy, Arnulf Langhammer, Bagher Larijani, Kurt Lippuner, Fiona E A McGuigan, Dan Mellström, Thomas Merlijn, Tuan V Nguyen, Anna Nordström, Peter Nordström, Terence W O Neill, Barbara Obermayer-Pietsch, Claes Ohlsson, Eric S Orwoll, Julie A Pasco, Fernando Rivadeneira, Anne-Marie Schott, Eric J Shiroma, Kristin Siggeirsdottir, Eleanor M Simonsick, Elisabeth Sornay-Rendu, Reijo Sund, Karin Swart, Pawel Szulc, Junko Tamaki, David J Torgerson, Natasja M van Schoor, Tjeerd P van Staa, Joan Vila, Nicole C Wright, Noriko Yoshimura, M Carola Zillikens, Marta Zwart, Nicholas C Harvey, Mattias Lorentzon, William D Leslie
  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 2025
• A perspective on muscle phenotyping in musculoskeletal research.

  Ines Foessl, Cheryl L Ackert-Bicknell, Erika Kague, Faidra Laskou, Franz Jakob, David Karasik, Barbara Obermayer-Pietsch, Nerea Alonso, Åshild Bjørnerem, Maria Luisa Brandi, Björn Busse, Ângelo Calado, Alper Han Cebi, Maria Christou, Kathleen M Curran, Jannie Dahl Hald, Maria Donatella Semeraro, Eleni Douni, Emma L Duncan, Ivan Duran, Melissa M Formosa, Yankel Gabet, Samuel Ghatan, Artemis Gkitakou, Eva Maria Hassler, Wolfgang Högler, Terhi J Heino, Gretl Hendrickx, Patricia Khashayar, Douglas P Kiel, Fjorda Koromani, Bente Langdahl, Philippe Lopes, Outi Mäkitie, Antonio Maurizi, Carolina Medina-Gomez, Evangelia Ntzani, Claes Ohlsson, Vid Prijatelj, Raquel Rabionet, Sjur Reppe, Fernando Rivadeneira, Gennady Roshchupkin, Neha Sharma, Kent Søe, Unnur Styrkarsdottir, Pavel Szulc, Anna Teti, Jon Tobias, Amina Valjevac, Jeroen van de Peppel, Bram van der Eerden, Bert van Rietbergen, Tatjana Zekic, M Carola Zillikens
  Trends in endocrinology and metabolism - 2024
• Associations of Testosterone and Related Hormones With All-Cause and Cardiovascular Mortality and Incident Cardiovascular Disease in Men : Individual Participant Data Meta-analyses.

  Bu B Yeap, Ross J Marriott, Girish Dwivedi, Robert J Adams, Leen Antonio, Christie M Ballantyne, Douglas C Bauer, Shalender Bhasin, Mary L Biggs, Peggy M Cawthon, David J Couper, Adrian S Dobs, Leon Flicker, David J Handelsman, Graeme J Hankey, Anke Hannemann, Robin Haring, Benjumin Hsu, Sean A Martin, Alvin M Matsumoto, Dan Mellström, Claes Ohlsson, Terence W O'Neill, Eric S Orwoll, Matteo Quartagno, Molly M Shores, Antje Steveling, Åsa Tivesten, Thomas G Travison, Dirk Vanderschueren, Gary A Wittert, Frederick C W Wu, Kevin Murray
  Annals of Internal Medicine - 2024
• GREM2 inactivation increases trabecular bone mass in mice

  Karin H. Nilsson, Petra Henning, Jianyao Wu, Klara Sjögren, Ulf H Lerner, Claes Ohlsson, Sofia Moverare-Skrtic
  Scientific Reports - 2024
• Predictive value of sarcopenia components for all-cause mortality: findings from population-based cohorts

  Leo D. Westbury, Nicholas C. Harvey, Charlotte Beaudart, Olivier Bruyere, Jane A. Cauley, Peggy Cawthon, Alfonso J. Cruz-Jentoft, Elizabeth M. Curtis, Kristine Ensrud, Roger A. Fielding, Helena Johansson, John A. Kanis, Magnus K. Karlsson, Nancy E. Lane, Laetitia Lengele, Mattias Lorentzon, Eugene McCloskey, Dan Mellström, Anne B. Newman, Claes Ohlsson, Eric Orwoll, Jean-Yves Reginster, Eva Ribom, Bjorn E. Rosengren, John T. Schousboe, Elaine M. Dennison, Cyrus Cooper
  Aging Clinical and Experimental Research - 2024
• Associations between gut microbiota and incident fractures in the FINRISK cohort

  Louise Grahnemo, Oleg Kambur, Leo Lahti, Pekka Jousilahti, Teemu Niiranen, Rob Knight, Veikko Salomaa, Aki S. Havulinna, Claes Ohlsson
  npj Biofilms and Microbiomes - 2024
• Dissecting the Impact of Maternal Androgen Exposure on Developmental Programming through Targeting the Androgen Receptor

  Haojiang Lu, Hong Jiang, Congru Li, Emilie Derisoud, Allan Zhao, Gustaw Eriksson, Eva Lindgren, Han-Pin Pui, Sanjiv Risal, Yu Pei, Theresa Maxian, Claes Ohlsson, Anna Benrick, Sandra Haider, Elisabet Stener-Victorin, Qiaolin Deng
  Advanced Science - 2024
• Publisher Correction: A plasma protein-based risk score to predict hip fractures.

  Thomas R Austin, Maria Nethander, Howard A Fink, Anna E Törnqvist, Diana I Jalal, Petra Buzkova, Joshua I Barzilay, Laura Carbone, Maiken E Gabrielsen, Louise Grahnemo, Tianyuan Lu, Kristian Hveem, Christian Jonasson, Jorge R Kizer, Arnulf Langhammer, Kenneth J Mukamal, Robert E Gerszten, Bruce M Psaty, John A Robbins, Yan V Sun, Anne Heidi Skogholt, John A Kanis, Helena Johansson, Bjørn Olav Åsvold, Rodrigo J Valderrabano, Jie Zheng, J Brent Richards, Eivind Coward, Claes Ohlsson
  Nature aging - 2024
• Postnatal Dysregulation of Androgens in Extremely Preterm Male Infants

  Anders K. Nilsson, Ulrika Sjöbom, Andreas Landin, Mats X. Andersson, Henrik Ryberg, Aldina Pivodic, Chatarina Löfqvist, Karin Sävman, Matti Poutanen, Claes Ohlsson, Ann Hellström
  Journal of the Endocrine Society (JES) - 2024
• Superior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy

  Miguel A. Sanchez-Garrido, Victor Serrano-Lopez, Francisco Ruiz-Pino, Maria Jesus Vazquez, Andrea Rodriguez-Martin, Encarnacion Torres, Inmaculada Velasco, Ana Belen Rodriguez, Eduardo Chicano-Galvez, Marina Mora-Ortiz, Claes Ohlsson, Matti Poutanen, Leonor Pinilla, Francisco Gaytan, Jonathan D. Douros, Bin Yang, Timo D. Mueller, Richard D. Dimarchi, Matthias H. Tschoep, Brian Finan, Manuel Tena-Sempere
  Nature Communications - 2024
• High SHBG and Low Bioavailable Testosterone are Strongly Causally Associated with Increased Forearm Fracture Risk in Women: An MR Study Leveraging Novel Female-Specific Data

  Johan Quester, Maria Nethander, Eivind Coward, Ene Reimann, Reedik Magi, Ulrika Pettersson-Kymmer, Kristian Hveem, Claes Ohlsson
  Calcified Tissue International - 2024
• Short-term risk of fracture is increased by deficits in cortical and trabecular bone microarchitecture independent of DXA BMD and FRAX: Bone Microarchitecture International Consortium (BoMIC) prospective cohorts.

  Marine Sarfati, Roland Chapurlat, Alyssa B Dufour, Elisabeth Sornay-Rendu, Blandine Merle, Steven K Boyd, Danielle E Whittier, David A Hanley, David Goltzman, Pawel Szulc, Andy Kin On Wong, Eric Lespessailles, Sundeep Khosla, Serge Ferrari, Emmanuel Biver, Claes Ohlsson, Mattias Lorentzon, Dan Mellström, Maria Nethander, Elizabeth J Samelson, Douglas P Kiel, Marian T Hannan, Mary L Bouxsein
  Journal of Bone and Mineral Research - 2024
• Sociodemographic, lifestyle, and medical factors associated with calculated free testosterone concentrations in men: individual participant data meta-analyses

  Nick Narinx, Ross J. Marriott, Kevin Murray, Robert J. Adams, Christie M. Ballantyne, Douglas C. Bauer, Shalender Bhasin, Mary L. Biggs, Peggy M. Cawthon, David J. Couper, Adrian S. Dobs, Leon Flicker, Graeme J. Hankey, Anke Hannemann, Robin Wilkening, Sean A. Martin, Alvin M. Matsumoto, Claes Ohlsson, Terence W. O'Neill, Eric S. Orwoll, Molly M. Shores, Antje Steveling, Thomas G. Travison, Gary A. Wittert, Frederick C. W. Wu, Leen Antonio, Dirk Vanderschueren, Bu B. Yeap
  European Journal of Endocrinology (EJE) - 2024
• Sex steroid levels in women with hypopituitarism: A case-controlled observational study.

  Catharina Olivius, Kerstin Landin-Wilhelmsen, Claes Ohlsson, Matti Poutanen, Penelope Trimpou, Daniel S Olsson, Gudmundur Johannsson, Åsa Tivesten
  The Journal of clinical endocrinology and metabolism - 2024
• Loading enhances glucose uptake in muscles, bones, and bone marrow of lower extremities in humans.

  Jakob Bellman, Tanja Sjöros, Daniel Hägg, Erika Atencio Herre, Janina Hieta, Olli Eskola, Kirsi Laitinen, Pirjo Nuutila, John-Olov Jansson, Per-Anders Jansson, Kari Kalliokoski, Anne Roivainen, Claes Ohlsson
  The Journal of clinical endocrinology and metabolism - 2024
• Tartrate-resistant acid phosphatase (TRAP/ACP5) promotes bone length, regulates cortical and trabecular bone mass, and maintains growth plate architecture and width in a sex- and site-specific manner in mice

  Bhavik Rathod, Suchita Desai, Hasmik Jasmine Samvelyan, Laura Bock, Jianyao Wu, Claes Ohlsson, Anders Palmquist, Jessica J. Alm, Phillip T. Newton, Goran Andersson, Sara H. Windahl
  BONE - 2024
• Femoral neck width genetic risk score is a novel independent risk factor for hip fractures

  Jonathan H. Tobias, Maria Nethander, Benjamin G. Faber, Sophie Heppenstall, Raja Ebsim, Tim Cootes, Claudia Lindner, Fiona R. Saunders, Jenny S. Gregory, Richard M. Aspden, Nicholas C. Harvey, John P. Kemp, Monika Frysz, Claes Ohlsson
  Journal of Bone and Mineral Research - 2024
• Higher FSH Level Is Associated With Increased Risk of Incident Hip Fracture in Older Adults, Independent of Sex Hormones

  Eileen H. Koh, Susan K. Ewing, Sigurdur Sigurdsson, Vilmundur Gudnason, Trisha F. Hue, Eric Vittinghoff, Claes Ohlsson, Åsa Tivesten, Louise Grahnemo, Tony Yuen, Mone Zaidi, Clifford J. Rosen, Ann Schwartz, Anne L. Schafer
  JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM - 2024
• A plasma protein-based risk score to predict hip fractures

  Thomas R. Austin, Maria Nethander, Howard A. Fink, Anna E Törnqvist, Diana I. Jalal, Petra Buzkova, Joshua I. Barzilay, Laura Carbone, Maiken E. Gabrielsen, Louise Grahnemo, Tianyuan Lu, Kristian Hveem, Christian Jonasson, Jorge R. Kizer, Arnulf Langhammer, Kenneth J. Mukamal, Robert E. Gerszten, Bruce M. Psaty, John A. Robbins, Yan V. Sun, Anne Heidi Skogholt, John A. Kanis, Helena Johansson, Bjorn Olav Asvold, Rodrigo J. Valderrabano, Jie Zheng, J. Brent Richards, Eivind Coward, Claes Ohlsson
  NATURE AGING - 2024
• Local Immune Activation and Age Impact on Humoral Immunity in Mice, with a Focus on IgG Sialylation.

  Priti Gupta, Tibor Sághy, Miriam Bollmann, Tao Jin, Claes Ohlsson, Hans Carlsten, Carmen Corciulo, Cecilia Engdahl
  Vaccines - 2024
• HSD17B1 Compensates for HSD17B3 Deficiency in Fetal Mouse Testis but Not in Adults.

  Arttu Junnila, Fu-Ping Zhang, Guillermo Martínez Nieto, Janne Hakkarainen, Juho-Antti Mäkelä, Claes Ohlsson, Petra Sipilä, Matti Poutanen
  Endocrinology - 2024
• Large-scale circulating proteome association study (CPAS) meta-analysis identifies circulating proteins and pathways predicting incident hip fractures.

  Thomas R Austin, Howard A Fink, Diana I Jalal, Anna E Törnqvist, Petra Buzkova, Joshua I Barzilay, Tianyuan Lu, Laura Carbone, Maiken E Gabrielsen, Louise Grahnemo, Kristian Hveem, Christian Jonasson, Jorge R Kizer, Arnulf Langhammer, Kenneth J Mukamal, Robert E Gerszten, Maria Nethander, Bruce M Psaty, John A Robbins, Yan V Sun, Anne Heidi Skogholt, Bjørn Olav Åsvold, Rodrigo J Valderrabano, Jie Zheng, J Brent Richards, Eivind Coward, Claes Ohlsson
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2024
• Higher serum free thyroxine levels are associated with increased risk of hip fractures in older men.

  Johan Svensson, Claes Ohlsson, Magnus K Karlsson, Hans Herlitz, Mattias Lorentzon, Catharina Lewerin, Dan Mellström
  Journal of Bone and Mineral Research - 2024
• Essential role of local antibody distribution in mediating bone-resorbing effects.

  Merja Nurkkala Karlsson, Marie K Lagerquist, Priti Gupta, Claes Ohlsson, Dan Mellström, Cecilia Engdahl
  Scientific reports - 2024
• Low birthweight and overweight during childhood and young adulthood and the risk of type 2 diabetes in men: a population-based cohort study.

  Jimmy Célind, Maria Bygdell, Rebecka Bramsved, Jari Martikainen, Claes Ohlsson, Jenny Kindblom
  Diabetologia - 2024
• A meta-analysis of previous falls and subsequent fracture risk in cohort studies.

  Liesbeth Vandenput, Helena Johansson, Eugene V McCloskey, Enwu Liu, Marian Schini, Kristina E Åkesson, Fred A Anderson, Rafael Azagra, Cecilie L Bager, Charlotte Beaudart, Heike A Bischoff-Ferrari, Emmanuel Biver, Olivier Bruyère, Jane A Cauley, Jacqueline R Center, Roland Chapurlat, Claus Christiansen, Cyrus Cooper, Carolyn J Crandall, Steven R Cummings, José A P da Silva, Bess Dawson-Hughes, Adolfo Diez-Perez, Alyssa B Dufour, John A Eisman, Petra J M Elders, Serge Ferrari, Yuki Fujita, Saeko Fujiwara, Claus-Christian Glüer, Inbal Goldshtein, David Goltzman, Vilmundur Gudnason, Jill Hall, Didier Hans, Mari Hoff, Rosemary J Hollick, Martijn Huisman, Masayuki Iki, Sophia Ish-Shalom, Graeme Jones, Magnus K Karlsson, Sundeep Khosla, Douglas P Kiel, Woon-Puay Koh, Fjorda Koromani, Mark A Kotowicz, Heikki Kröger, Timothy Kwok, Olivier Lamy, Arnulf Langhammer, Bagher Larijani, Kurt Lippuner, Fiona E A McGuigan, Dan Mellström, Thomas Merlijn, Tuan V Nguyen, Anna Nordström, Peter Nordström, Terence W O'Neill, Barbara Obermayer-Pietsch, Claes Ohlsson, Eric S Orwoll, Julie A Pasco, Fernando Rivadeneira, Anne-Marie Schott, Eric J Shiroma, Kristin Siggeirsdottir, Eleanor M Simonsick, Elisabeth Sornay-Rendu, Reijo Sund, Karin M A Swart, Pawel Szulc, Junko Tamaki, David J Torgerson, Natasja M van Schoor, Tjeerd P van Staa, Joan Vila, Nicholas J Wareham, Nicole C Wright, Noriko Yoshimura, MCarola Zillikens, Marta Zwart, Nicholas C Harvey, Mattias Lorentzon, William D Leslie, John A Kanis
  Osteoporosis International - 2024
• Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults.

  NCD Risk Factor Collaboration (NCD RisC), Cecilia Björkelund, Robert Eggertsen, Dominique Hange, Lauren Lissner, Kirsten Mehlig, Claes Ohlsson, Jenny Kindblom, Agneta Sjöberg, Annika Rosengren
  Lancet (London, England) - 2024
• Birth Weight, Childhood and Young Adult Overweight, and the Risk of Coronary Heart Disease in Men.

  Rebecka Bramsved, Maria Bygdell, Jari Martikainen, Staffan Mårild, Ingela Lindh, Annika Rosengren, Claes Ohlsson, Jenny Kindblom
  Arteriosclerosis, thrombosis, and vascular biology - 2024
• Humanin Treatment Protects Against Venetoclax-Induced Bone Growth Retardation in Ex Vivo Cultured Rat Bones

  Lilly Velentza, Malin Wickstrom, Per Kogner, Claes Ohlsson, Farasat Zaman, Lars Saevendahl
  JOURNAL OF THE ENDOCRINE SOCIETY - 2024

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