Johanna Andersson Assarsson
Om Johanna Andersson Assarsson
Johanna Andersson Assarsson är Doktor i Medicinsk vetenskap och forskare vid avdelningen för molekylär och klinisk medicin samt forskningskoordinator för Swedish Obese Subjects (SOS)-studien.
Forskning:
Johanna disputerade vid avdelningen för patologi på Göteborgs universitet 2005 med en avhandling som fokuserade på betydelsen av mutationer i tyrosinkinasreceptorer för prognos och behandling av gastrointestinala stromacellstumörer (GIST). Efter disputationen flyttade hon till London för en post doc på Imperial College London, vid avdelningen för Genomics of Common Disease, School of Public Health. Under tiden i London jobbade Johanna med storskaliga genetiska analyser (GWAS och CNV) inom fetma.
Sedan 2010 jobbar Johanna inom SOS-studien med studier kring fetma och relaterade sjukdomar, ofta med ett fokus på genetik. SOS-studien startade 1987 och omfattar 4047 individer. Studien undersöker långtidseffekter av viktnedgång genom bariatrisk kirurgi.
Mer information om studien och populärvetenskapliga sammanfattningar av studiens viktigaste publikationer finns här: SOS-zonen på HOBS.
Nyckelord: Fetma, diabetes, hjärtkärlsjukdom, genetik, storskalig dataanalys, R
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Human adipose tissue gene expression of solute carrier family 19 member 3 (SLC19A3); relation to obesity and
weight-loss
M. J. Pereira, Johanna C. Andersson-Assarsson, Peter Jacobson, P. Kamble, Magdalena Taube, Kajsa Sjöholm, Lena M S Carlsson, Per-Arne Svensson
Obesity Science & Practice - 2022 -
A SNP in the 5’ flanking region of the SAA1 gene is associated with serum levels of serum amyloid A and cardiovascular risk
factors.
Sofie Ahlin, Maja Löfgren, Magdalena Taube, Johanna C. Andersson-Assarsson, Markku Peltonen, Per-Arne Svensson, Peter Jacobson, Lena M S Carlsson, Kajsa Sjöholm
Translational Medicine Communications - 2022 -
Association of Bariatric Surgery With Cancer Incidence in Patients With Obesity and Diabetes: Long-Term Results From the Swedish Obese Subjects
Study.
Kajsa Sjöholm, Lena M S Carlsson, Per-Arne Svensson, Johanna C. Andersson-Assarsson, Felipe M. Kristensson, Peter Jacobson, Markku Peltonen, Magdalena Taube
Diabetes care - 2022 -
Expansion of mutation-driven haematopoietic clones is associated with insulin resistance and low HDL-cholesterol in individuals with
obesity
Rosanne van Deuren, Johanna Andersson, Felipe M. Kristensson, Marloes Steehouwer, Kajsa Sjöholm, Per-Arne Svensson, Marc Pieterse, Christian Gilissen, Magdalena Taube, Peter Jacobson, Rosie Perkins, Han Brunner, Mihai Netea, Markku Peltonen, Björn Carlsson, Alexander Hoischen, Lena M S Carlsson
bioRxiv - 2021 -
Long-term incidence of colorectal cancer after bariatric surgery or usual care in the Swedish Obese Subjects
study.
Magdalena Taube, Markku Peltonen, Kajsa Sjöholm, Richard Palmqvist, Johanna C. Andersson-Assarsson, Peter Jacobson, Per-Arne Svensson, Carlsson Lena
PloS one - 2021 -
Adiponectin Associates with Rheumatoid Arthritis Risk in Overweight and Obesity Independently of Other
Adipokines
Yuan Zhang, L. Johansson, Johanna C. Andersson-Assarsson, Magdalena Taube, M. Peltonen, Per-Arne Svensson, C. Herder, Anna Rudin, Lena M S Carlsson, S. Rantapaa-Dahlqvist, Cristina Maglio
Journal of Clinical Medicine - 2021 -
Long-term incidence of hypoglycaemia-related events after bariatric surgery or usual care in the Swedish Obese Subjects study: A register-based
analysis
Kajsa Sjöholm, Peter Jacobson, Magdalena Taube, Per-Arne Svensson, Johanna C. Andersson-Assarsson, Lena M S Carlsson, M. Peltonen
Diabetes Obesity & Metabolism - 2021 -
Heart failure development in obesity: underlying risk factors and mechanistic
pathways.
Shabbar Jamaly, Lena M S Carlsson, Markku Peltonen, Johanna C. Andersson-Assarsson, Kristjan Karason
ESC heart failure - 2021 -
Remission and progression of pre-existing micro- and macroalbuminuria over 15 years after bariatric surgery in Swedish Obese Subjects
study.
Alexander Shulman, Johanna C. Andersson-Assarsson, C D Sjöström, Peter Jacobson, Magdalena Taube, Kajsa Sjöholm, C W le Roux, M Peltonen, Carlsson Lena, Per-Arne Svensson
International journal of obesity - 2021 -
Interaction Effect Between Copy Number Variation in Salivary Amylase Locus (AMY1) and Starch Intake on Glucose Homeostasis in the Malmo Diet and Cancer
Cohort
A. K. Hamid, Johanna C. Andersson-Assarsson, U. Ericson, E. Sonestedt
Frontiers in Nutrition - 2021 -
Elevated adiponectin predicts the development of rheumatoid arthritis in subjects with
obesity
Y Zhang, M. Peltonen, Johanna C. Andersson-Assarsson, Per-Arne Svensson, C. Herder, Anna Rudin, Lena M S Carlsson, Cristina Maglio
Scandinavian Journal of Rheumatology - 2020 -
Life Expectancy after Bariatric Surgery in the Swedish Obese Subjects
Study.
Carlsson Lena, Kajsa Sjöholm, Peter Jacobson, Johanna C. Andersson-Assarsson, Per-Arne Svensson, Magdalena Taube, Björn Carlsson, Markku Peltonen
The New England journal of medicine - 2020 -
Alpha-amylase 1A copy number variants and the association with memory performance and Alzheimer's
dementia
E. Byman, K. Nagga, A. M. Gustavsson, Johanna C. Andersson-Assarsson, O. Hansson, E. Sonestedt, M. Wennstrom, Bank Netherlands Brain
Alzheimers Research & Therapy - 2020 -
9p21.3 Coronary Artery Disease Locus Identifies Patients With Treatment Benefit From Bariatric Surgery in the Nonrandomized Prospective Controlled Swedish Obese Subjects
Study.
Peter Jacobson, Markku Peltonen, Per-Arne Svensson, Magdalena Taube, Johanna C. Andersson-Assarsson, Kajsa Sjöholm, Claude Bouchard, Björn Carlsson, Lena M S Carlsson
Circulation. Genomic and precision medicine - 2020 -
Evaluation of Prediction Models for Type 2 Diabetes Relapse After Post-bariatric Surgery Remission: a Post hoc Analysis of 15-Year Follow-up Data from the Swedish Obese Subjects (SOS)
Study.
Kajsa Sjöholm, Per-Arne Svensson, Magdalena Taube, Peter Jacobson, Johanna C. Andersson-Assarsson, Carlsson Lena, Markku Peltonen
Obesity surgery - 2020 -
Fracture risk after three bariatric surgery procedures in Swedish obese subjects: up to 26 years follow-up of a controlled intervention
study.
Sofie Ahlin, M Peltonen, Kajsa Sjöholm, Åsa Anveden, Peter Jacobson, Johanna C. Andersson-Assarsson, Magdalena Taube, I Larsson, L S Lohmander, I Näslund, Per-Arne Svensson, Lena M S Carlsson
Journal of internal medicine - 2020 -
Association of Bariatric Surgery With Skin Cancer Incidence in Adults With Obesity: A Nonrandomized Controlled
Trial.
Magdalena Taube, Markku Peltonen, Kajsa Sjöholm, Åsa Anveden, Johanna C. Andersson-Assarsson, Peter Jacobson, Per-Arne Svensson, Martin O. Bergö, Carlsson Lena
JAMA dermatology - 2020 -
Effects of Bariatric Surgery in Early- and Adult-Onset Obesity in the Prospective Controlled Swedish Obese Subjects
Study.
Felipe M. Kristensson, Johanna C. Andersson-Assarsson, Per-Arne Svensson, Björn Carlsson, Markku Peltonen, Lena M S Carlsson
Diabetes care - 2020 -
Bariatric surgery and the incidence of rheumatoid arthritis - a Swedish Obese Subjects
study.
Cristina Maglio, Yuan Zhang, Markku Peltonen, Johanna C. Andersson-Assarsson, Per-Arne Svensson, Christian Herder, Anna Rudin, Lena M S Carlsson
Rheumatology - 2020 -
Expression of GHR and Downstream Signaling Genes in Human Adipose Tissue-Relation to Obesity and Weight
Change.
Camilla A M Glad, Per-Arne Svensson, Fredrik H Nystrom, Peter Jacobson, Lena M S Carlsson, Gudmundur Johannsson, Johanna C. Andersson-Assarsson
The Journal of clinical endocrinology and metabolism - 2019 -
Reoperations After Bariatric Surgery in 26 Years of Follow-up of the Swedish Obese Subjects
Study.
Stephan Hjorth, Ingmar Näslund, Johanna C. Andersson-Assarsson, Per-Arne Svensson, Peter Jacobson, Markku Peltonen, Lena M S Carlsson
JAMA surgery - 2019 -
Long-term incidence of serious fall-related injuries after bariatric surgery in Swedish obese
subjects.
Lena M S Carlsson, Kajsa Sjöholm, Sofie Ahlin, Peter Jacobson, Johanna C. Andersson-Assarsson, Linda Karlsson-Lindahl, Cristina Maglio, Cecilia Karlsson, Stephan Hjorth, Magdalena Taube, Björn Carlsson, Per-Arne Svensson, Markku Peltonen
International journal of obesity (2005) - 2019 -
Self-Reported Weight-Loss Methods and Weight Change: Ten-Year Analysis in the Swedish Obese Subjects Study Control
Group
Edit Zenténius, Johanna C. Andersson-Assarsson, Lena M S Carlsson, Per-Arne Svensson, Ingrid Larsson
Obesity - 2018 -
Incidence of end-stage renal disease following bariatric surgery in the Swedish Obese Subjects
Study.
Alexander Shulman, Markku Peltonen, C D Sjöström, Johanna C. Andersson-Assarsson, Magdalena Taube, Kajsa Sjöholm, Carel W le Roux, Lena M S Carlsson, Per-Arne Svensson
International journal of obesity - 2018 -
Copy number of pancreatic polypeptide receptor gene NPY4R correlates with body mass index and waist
circumference
K. Shebanits, Johanna C. Andersson-Assarsson, I. Larsson, Lena M S Carlsson, L. Feuk, D. Larhammar
Plos One - 2018 -
AMYCNE: Confident copy number assessment using whole genome sequencing
data
J. Eisfeldt, D. Nilsson, Johanna C. Andersson-Assarsson, A. Lindstrand
Plos One - 2018 -
Long-term effects of bariatric surgery in patients with obesity and chromosome 16 p11.2
microdeletion
Felipe M. Kristensson, Johanna C. Andersson-Assarsson, Noora Kanerva, M. Peltonen, Björn Carlsson, Lena M S Carlsson
Surgery for Obesity and Related Diseases - 2017 -
Long-term incidence of microvascular disease after bariatric surgery or usual care in patients with obesity, stratified by baseline glycaemic status: a post-hoc analysis of participants from the Swedish Obese Subjects
study.
Lena M S Carlsson, Kajsa Sjöholm, Cecilia Karlsson, Peter Jacobson, Johanna C. Andersson-Assarsson, Per-Arne Svensson, Ingrid Larsson, Stephan Hjorth, Martin Neovius, Magdalena Taube, Björn Carlsson, Markku Peltonen
The lancet. Diabetes & endocrinology - 2017 -
Copy Number Variants Are Enriched in Individuals With Early-Onset Obesity and Highlight Novel Pathogenic
Pathways
M. Pettersson, H. Viljakainen, P. Loid, T. Mustila, M. Pekkinen, M. Armenio, Johanna C. Andersson-Assarsson, O. Makitie, A. Lindstrand
Journal of Clinical Endocrinology & Metabolism - 2017 -
Dietary starch intake modifies the relation between copy number variation in the salivary amylase gene and
BMI
G. Rukh, U. Ericson, Johanna C. Andersson-Assarsson, M. Orho-Melander, E. Sonestedt, Journal Of Internal Medicine V. P. Llmer E
American Journal of Clinical Nutrition - 2017 -
Long-term incidence of female-specific cancer after bariatric surgery or usual care in the Swedish Obese Subjects
Study
Åsa Anveden, Magdalena Taube, M. Peltonen, Peter Jacobson, Johanna C. Andersson-Assarsson, Kajsa Sjöholm, Per-Arne Svensson, Lena M S Carlsson
Gynecologic Oncology - 2017 -
Reduced DNA methylation and psychopathology following endogenous hypercortisolism- a genome-wide
study
Camilla A M Glad, Johanna C. Andersson-Assarsson, Peter Berglund, Ragnhildur Bergthorsdottir, Oskar Ragnarsson, Gudmundur Johannsson
Scientific Reports - 2017 -
Evaluation of reference genes for gene expression studies in human brown adipose
tissue.
Magdalena Taube, Johanna C. Andersson-Assarsson, Kristin Lindberg, Maria J Pereira, Markus Gäbel, Maria K Svensson, Jan W Eriksson, Per-Arne Svensson
Adipocyte - 2015 -
Low Copy Number of the AMY1 Locus Is Associated with Early-Onset Female Obesity in
Finland
H. Viljakainen, Johanna C. Andersson-Assarsson, M. Armenio, M. Pekkinen, M. Pettersson, H. Valta, M. Lipsanen-Nyman, O. Makitie, A. Lindstrand
Plos One - 2015 -
Low copy number of the salivary amylase gene predisposes to
obesity
M. Falchi, J. S. El-Sayed Moustafa, P. Takousis, F. Pesce, A. Bonnefond, Johanna C. Andersson-Assarsson, P. H. Sudmant, R. Dorajoo, M. N. Al-Shafai, L. Bottolo, E. Ozdemir, H. C. So, R. W. Davies, A. Patrice, R. Dent, M. Mangino, P. G. Hysi, A. Dechaume, M. Huyvaert, J. Skinner, M. Pigeyre, R. Caiazzo, V. Raverdy, E. Vaillant, S. Field, B. Balkau, M. Marre, S. Visvikis-Siest, J. Weill, O. Poulain-Godefroy, Peter Jacobson, Lars Sjöström, C. J. Hammond, P. Deloukas, P. C. Sham, R. McPherson, J. Lee, E. S. Tai, R. Sladek, Lena M S Carlsson, A. Walley, E. E. Eichler, F. Pattou, T. D. Spector, P. Froguel
Nature Genetics - 2014 -
Association of Bariatric Surgery With Long-term Remission of Type 2 Diabetes and With Microvascular and Macrovascular
Complications
Lars Sjöström, Markku Peltonen, Peter Jacobson, Sofie Ahlin, Johanna C. Andersson-Assarsson, Åsa Anveden, Bouchard Claude, Björn Carlsson, Kristjan Karason, Hans Lönroth, Ingmar Näslund, Elisabeth Sjöström, Magdalena Taube, Hans Wedel, Per-Arne Svensson, Kajsa Sjöholm, Lena M S Carlsson
Journal of the American Medical Association - 2014 -
The IRS1 rs2943641 Variant and Risk of Future Cancer Among Morbidly Obese
Individuals.
Cristina Maglio, Ulrika Ericson, Maria Antonella Burza, Rosellina Margherita Mancina, Carlo Pirazzi, Johanna C. Andersson-Assarsson, Kajsa Sjöholm, Marco Giorgio Baroni, Per-Arne Svensson, Tiziana Montalcini, Arturo Pujia, Lars Sjöström, Olov Wiklund, Lena M S Carlsson, Jan Borén, Marju Orho-Melander, Stefano Romeo
The Journal of clinical endocrinology and metabolism - 2013 -
Adipose Tissue Resting Energy Expenditure and Expression of Genes Involved in Mitochondrial Function Are Higher in Women than in
Men.
Intawat Nookaew, Per-Arne Svensson, Peter Jacobson, Margareta Jernås, Magdalena Taube, Ingrid Larsson, Johanna C. Andersson-Assarsson, Lars Sjöström, Philippe Froguel, Andrew Walley, Jens B. Nielsen, Lena M S Carlsson
The Journal of clinical endocrinology and metabolism - 2013 -
Macrophage Gene Expression in Adipose Tissue is Associated with Insulin Sensitivity and Serum Lipid Levels Independent of
Obesity.
Sofie Ahlin, Kajsa Sjöholm, Peter Jacobson, Johanna C. Andersson-Assarsson, A Walley, J Tordjman, C Poitou, E Prifti, Per-Anders Jansson, Jan Borén, Lars Sjöström, P Froguel, R N Bergman, Lena M S Carlsson, Bob Olsson, Per-Arne Svensson
Obesity (Silver Spring, Md.) - 2013 -
The TGR5 gene is expressed in human subcutaneous adipose tissue and is associated with obesity,Weight loss and resting metabolic
rate
Per-Arne Svensson, Maja Olsson, Johanna C. Andersson-Assarsson, Magdalena Taube, Maria J Pereira, P. Froguel, Peter Jacobson
Biochemical and Biophysical Research Communications - BBRC - 2013 -
Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe
obesity
J. S. E. Moustafa, H. Eleftherohorinou, A. J. de Smith, Johanna C. Andersson-Assarsson, A. C. Alves, E. Hadjigeorgiou, R. G. Walters, J. E. Asher, L. Bottolo, J. L. Buxton, R. Sladek, D. Meyre, C. Dina, S. Visvikis-Siest, Peter Jacobson, Lars Sjöström, Lena M S Carlsson, A. Walley, M. Falchi, P. Froguel, A. I. F. Blakemore, L. J. M. Coin
Human Molecular Genetics - 2012 -
Differential coexpression analysis of obesity-associated networks in human subcutaneous adipose
tissue.
A J Walley, Peter Jacobson, M Falchi, L Bottolo, Johanna Andersson, E Petretto, A Bonnefond, E Vaillant, C Lecoeur, V Vatin, Margareta Jernås, D Balding, M Petteni, Y S Park, T Aitman, S Richardson, Lars Sjöström, Lena M S Carlsson, P Froguel
International Journal of Obesity - 2012 -
Association of Sirtuin 1 (SIRT1) Gene SNPs and Transcript Expression Levels With Severe
Obesity.
Stephen J Clark, Mario Falchi, Bob Olsson, Peter Jacobson, Stéphane Cauchi, Beverley Balkau, Michel Marre, Olivier Lantieri, Johanna Andersson, Margareta Jernås, Timothy J Aitman, Sylvia Richardson, Lars Sjöström, Hang Y Wong, Lena M S Carlsson, Philippe Froguel, Andrew J Walley
Obesity - 2012 -
famCNV: copy number variant association for quantitative traits in
families.
Hariklia Eleftherohorinou, Johanna Andersson, Robin G Walters, Julia S El-Sayed Moustafa, Lachlan Coin, Peter Jacobson, Lena M S Carlsson, Alexandra I F Blakemore, Philippe Froguel, Andrew J Walley, Mario Falchi
Bioinformatics (Oxford, England) - 2011 -
The contribution of heredity to clinical
obesity
Andrew Walley, Johanna Andersson
Lustig, R (Ed): Obesity before birth - 2011 -
Gastrointestinal stromal tumour with a KIT exon 11 mutation presenting as a paratesticular
mass.
S Hilman, S Sothi, D Peake, Johanna Andersson, JM Meis
The British journal of radiology - 2009 -
Adjuvant imatinib treatment improves recurrence-free survival in patients with high-risk gastrointestinal stromal tumours
(GIST)
Bengt E Nilsson, Katarina Sjölund, Lars-Gunnar Kindblom, Jeanne Meis-Kindblom, Per Bümming, Ola Nilsson, Johanna Andersson, Håkan Ahlman
British journal of cancer - 2007 -
Population-based study of the diagnosis and treatment of gastrointestinal stromal
tumours
Per Bümming, Håkan Ahlman, Johanna Andersson, Jeanne Meis-Kindblom, Lars-Gunnar Kindblom, Bengt E Nilsson
The British journal of surgery - 2006 -
Gastrointestinal stromal tumors with KIT exon 11 deletions are associated with poor
prognosis
Johanna Andersson, Per Bümming, Jeanne Meis-Kindblom, H. Sihto, N. Nupponen, H. Joensuu, Anders Odén, B. Gustavsson, Lars-Gunnar Kindblom, Bengt E Nilsson
Gastroenterology - 2006 -
NF1 associated gastrointestinal stromal tumors have unique clinical, phenotypic, and genotypic
characteristics
Johanna Andersson, Harri Sihto, Jeanne Meis-Kindblom, Heikki Joensuu, N. N. Nupponen, Lars-Gunnar Kindblom
American Journal of Surgical Pathology - 2005 -
Gastrointestinal stromal tumors. Pathogenetic mechanisms, phenotypic characterization and
prognosis
Johanna Andersson
2005 -
Neoadjuvant, adjuvant and palliative treatment of gastrointestinal stromal tumours (GIST) with imatinib: a centre-based study of 17
patients.
Per Bümming, Johanna Andersson, Jeanne Meis-Kindblom, Hans Klingenstierna, Katarina Engström, Ulrika Stierner, Bo Wängberg, Svante Jansson, Håkan Ahlman, Lars-Gunnar Kindblom, Bengt E Nilsson
British journal of cancer - 2003 -
[GIST--a significantly more common tumor than earlier apprehended. New discoveries on the pathogenesis of GIST yielded new medical
treatment]
Bengt E Nilsson, Johanna Andersson, Jeanne Meis-Kindblom, Lars-Gunnar Kindblom, Katarina Engström, Ulrika Stierner, Per Bümming, Håkan Ahlman
Läkartidningen - 2003 -
The complexity of KIT gene mutations and chromosomal rearrangements and their clinical correlations in gastrointestinal stromal (pacemaker cell)
tumors
Johanna Andersson, Helene Sjögren, Jeanne Meis-Kindblom, Göran Stenman, Pierre Åman, Lars-Gunnar Kindblom
American Journal of Pathology - 2002