Georgios Lappas
-
Long-term survival in patients with isolated pulmonary valve stenosis: a not so benign
disease?
Kristofer Skoglund, Annika Rosengren, Georgios Lappas, Maria Fedchenko, Zacharias Mandalenakis
Open Heart - 2021-01-01 -
Severe COVID-19 in people with type 1 and type 2 diabetes in Sweden: A nationwide retrospective cohort
study.
Aidin Rawshani, Elin Allansson Kjölhede, Araz Rawshani, Naveed Sattar, Katarina Eeg-Olofsson, Martin Adiels, Johnny Ludvigsson, Marcus Lind, Magnus Gisslén, Eva Hagberg, Georg Lappas, Björn Eliasson, Annika Rosengren
The Lancet regional health. Europe - 2021-01-01 -
Mid-life extrapyramidal symptoms predict cognitive impairment 23 years
later
Charlotte Holtback, Catharina Welin, Michael Fu, Erik Thunström, Annika Rosengren, Georgios Lappas, Per-Olof Hansson
Acta Neurologica Scandinavica - 2021-01-01 -
Mortality burden in patients born with Ebstein's anomaly: a 40-year nationwide cohort
study.
Filip Eckerström, Peter J Eriksson, Mikael Dellborg, Georgios Lappas, Annika Rosengren, Vibeke Elisabeth Hjortdal, Zacharias Mandalenakis
European heart journal. Quality of care & clinical outcomes - 2021-01-01 -
Social Support and Subclinical Coronary Artery Disease in Middle-Aged Men and Women: Findings from the Pilot of Swedish CArdioPulmonary bioImage
Study
D. Djekic, Erika Fagman, Oskar Angerås, Georgios Lappas, Kjell Torén, Göran Bergström, Annika Rosengren
International Journal of Environmental Research and Public Health - 2020-01-01 -
Development of heart failure in young patients with congenital heart disease: a nation-wide cohort
study.
Thomas Gilljam, Zacharias Mandalenakis, Mikael Dellborg, Georgios Lappas, Peter J Eriksson, Kristofer Skoglund, Annika Rosengren
Open heart - 2019-01-01 -
Risk of Cancer Among Children and Young Adults With Congenital Heart Disease Compared With Healthy
Controls
Zacharias Mandalenakis, Christina Karazisi, Kristofer Skoglund, Annika Rosengren, Georgios Lappas, Peter J Eriksson, Mikael Dellborg
Jama Network Open - 2019-01-01 -
Impact of socioeconomic status on coronary artery
calcification
D. Djekic, Oskar Angerås, Georg Lappas, Erika Fagman, Björn Fagerberg, Göran Bergström, Annika Rosengren
European Journal of Preventive Cardiology - 2018-01-01 -
Association of diuretic treatment at hospital discharge in patients with heart failure with all-cause short- and long-term mortality: A propensity score-matched analysis from
SwedeHF
Pär Parén, U. Dahlström, M. Edner, Georg Lappas, Annika Rosengren, Maria Schaufelberger
International Journal of Cardiology - 2018-01-01 -
Atrial Fibrillation Burden in Young Patients with Congenital Heart
Disease.
Zacharias Mandalenakis, Annika Rosengren, Georg Lappas, Peter J Eriksson, Thomas Gilljam, Per-Olof Hansson, Kristofer Skoglund, Maria Fedchenko, Mikael Dellborg
Circulation - 2018-01-01 -
Long-Term Risk of Hemorrhagic Stroke in Young Patients With Congenital Heart
Disease
Kok Wai Giang, Zacharias Mandalenakis, Mikael Dellborg, Georg Lappas, Peter J Eriksson, Per-Olof Hansson, Annika Rosengren
Stroke - 2018-01-01 -
Sex differences in survival after myocardial infarction in Sweden,
1987-2010
Johanna Berg, Lena Björck, Susanne Nielsen, Georg Lappas, Annika Rosengren
Heart - 2017-01-01 -
Ischemic heart disease in children and young adults with congenital heart disease in
Sweden
Maria Fedchenko, Zacharias Mandalenakis, Annika Rosengren, Georg Lappas, Peter J Eriksson, Kristofer Skoglund, Mikael Dellborg
International Journal of Cardiology - 2017-01-01 -
Risk of Heart Failure in Obese Patients With and Without Bariatric Surgery in Sweden-A Registry-Based
Study
Christina Persson, Lena Björck, Georg Lappas, Kok Wai Giang, Annika Rosengren
Journal of Cardiac Failure - 2017-01-01 -
Long-term trends in the prevalence of patients hospitalized with ischemic stroke from 1995 to 2010 in
Sweden
Kok Wai Giang, Zacharias Mandalenakis, Susanne Nielsen, Lena Björck, Georg Lappas, Martin Adiels, Christina Jern, Annika Rosengren
Plos One - 2017-01-01 -
Survivorship in Children and Young Adults With Congenital Heart Disease in
Sweden
Zacharias Mandalenakis, Annika Rosengren, Kristofer Skoglund, Georg Lappas, Peter J Eriksson, Mikael Dellborg
JAMA internal medicine - 2017-01-01 -
Physical Activity Levels and Their Associations With Postural Control in the First Year After
Stroke
Carina Ulla Persson, Per-Olof Hansson, Georg Lappas, Anna Danielsson
Physical Therapy - 2016-01-01 -
Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million
participants.
Bin Zhou, Yuan Lu, Kaveh Hajifathalian, James Bentham, Cecilia Björkelund, Robert Eggertsen, Georg Lappas, Lauren Lissner, Annika Rosengren, Julio Zuniga Cisneros
Lancet (London, England) - 2016-01-01 -
Living alone predicts mortality in patients with ischemic stroke before 70 years of age: a long-term prospective follow-up
study
Petra Redfors, Daniella Isaksén, Georg Lappas, Christian Blomstrand, Annika Rosengren, Katarina Jood, Christina Jern
BMC neurology - 2016-01-01 -
Physical activity pattern, cardiorespiratory fitness, and socioeconomic status in the SCAPIS pilot trial - A cross-sectional
study
Martin Lindgren, Mats Börjesson, O. Ekblom, Göran Bergström, Georg Lappas, Annika Rosengren
Preventive medicine reports - 2016-01-01 -
A century of trends in adult human
height
James Bentham, Mariachiara Di Cesare, Gretchen A Stevens, Bin Zhou, Honor Bixby, Melanie Cowan, Cecilia Björkelund, Robert Eggertsen, Georg Lappas, Lauren Lissner, Annika Rosengren
eLife - 2016-01-01 -
Ischemic Stroke in Children and Young Adults With Congenital Heart
Disease
Zacharias Mandalenakis, Annika Rosengren, Georg Lappas, Peter J Eriksson, Per-Olof Hansson, Mikael Dellborg
Journal of the American Heart Association - 2016-01-01 -
Effects of Probiotic Intake and Gender on Nontyphoid Salmonella
Infection
Elisabeth Lönnermark, Georg Lappas, Vanda Friman, Agnes E Wold, Erik Backhaus, Ingegerd Adlerberth
Journal of Clinical Gastroenterology - 2015-01-01 -
Decline in Coronary Mortality in Sweden between 1986 and 2002: Comparing Contributions from Primary and Secondary
Prevention
Lena Björck, S. Capewell, M. O'Flaherty, Georg Lappas, K. Bennett, Annika Rosengren
Plos One - 2015-01-01 -
Atrial natriuretic peptide as a predictor of atrial fibrillation in a male population study. The Study of Men Born in 1913 and
1923
Zacharias Mandalenakis, Henry Eriksson, Lennart Welin, Kenneth Caidahl, Mikael Dellborg, Annika Rosengren, Georg Lappas, Jan A Hedner, Saga Johansson, K. Svardsudd, Per-Olof Hansson
International Journal of Cardiology - 2014-01-01 -
Heart failure in young adults: 20-year trends in hospitalization, aetiology, and case fatality in
Sweden
Anders Barasa, Maria Schaufelberger, Georg Lappas, Karl Swedberg, Mikael Dellborg, Annika Rosengren
European Heart Journal - 2014-01-01 -
Trends in prevalence from 1990 to 2007 of patients hospitalized with heart failure in
Sweden
Pär Paren, Maria Schaufelberger, Lena Björck, Georg Lappas, Michael Fu, Annika Rosengren
European Journal of Heart Failure - 2014-01-01 -
Continuing decrease in coronary heart disease mortality in
sweden
Johanna Berg, Lena Björck, Georg Lappas, Martin O'Flaherty, Simon Capewell, Annika Rosengren
BMC Cardiovascular Disorders - 2014-01-01 -
Incidence of Type 2 diabetes among occupational classes in Sweden: a 35-year follow-up cohort study in middle-aged
men
Christina Hedén Ståhl, Masuma Novak, Per-Olof Hansson, Georg Lappas, Lars Wilhelmsen, Annika Rosengren
Diabetic Medicine - 2014-01-01 -
Differences between acute myocardial infarction and unstable angina: a longitudinal cohort study reporting findings from the Register of Information and Knowledge about Swedish Heart Intensive Care Admissions
(RIKS-HIA)
Kerstin Dudas, Lena Björck, Tomas Jernberg, Georg Lappas, Lars Wallentin, Annika Rosengren
BMJ open - 2013-01-01 -
Trends in stroke incidence after hospitalization for atrial fibrillation in Sweden 1987 to
2006
Lars G. Olsson, Karl Swedberg, Georg Lappas, S. Stewart, Annika Rosengren
International journal of cardiology - 2013-01-01 -
Occupational status and incidences of ischemic and hemorrhagic stroke in Swedish men: a population-based 35-year prospective follow-up
study
Masuma Novak, Kjell Torén, Georg Lappas, Kok Wai Giang, Christina Jern, Lars Wilhelmsen, Annika Rosengren
European Journal of Epidemiology - 2013-01-01 -
Twenty-Four-Year Trends in the Incidence of Ischemic Stroke in Sweden From 1987 to
2010
Annika Rosengren, Kok Wai Giang, Georg Lappas, Christina Jern, Kjell Torén, Lena Björck
Stroke - 2013-01-01 -
Trends in mortality after first hospitalization with Atrial Fibrillation diagnosis in Sweden 1987 to
2006
Lars G. Olsson, Karl Swedberg, Georg Lappas, S. Stewart, Annika Rosengren
International Journal of Cardiology - 2013-01-01 -
Stroke and coronary heart disease: predictive power of standard risk factors into old age-long-term cumulative risk study among men in Gothenburg,
Sweden
Kok Wai Giang, Lena Björck, Masuma Novak, Georg Lappas, Lars Wilhelmsen, Kjell Torén, Annika Rosengren
European Heart Journal - 2013-01-01 -
Self-reported leisure time physical activity: a useful assessment tool in everyday health
care
Lars Rödjer, Ingibjörg H Jonsdottir, Annika Rosengren, Lena Björck, Gunnar Grimby, Dag Thelle, Georg Lappas, Mats Börjesson
BMC public health - 2012-01-01 -
Long-term prognosis after hospital admission for acute myocardial infarction from 1987 to
2006
Kerstin Dudas, Georg Lappas, Annika Rosengren
International Journal of Cardiology - 2012-01-01 -
High-normal blood pressure and long-term risk of type 2 diabetes: 35-year prospective population based cohort study of
men
Christina Hedén Ståhl, Masuma Novak, Georg Lappas, Lars Wilhelmsen, Lena Björck, Per-Olof Hansson, Annika Rosengren
BMC cardiovascular disorders - 2012-01-01 -
Increasing evidence-based treatments to reduce coronary heart disease mortality in Sweden: quantifying the potential
gains
Lena Björck, S. Capewell, K. Bennett, Georg Lappas, Annika Rosengren
Journal of internal medicine - 2011-01-01 -
Trends in Out-of-Hospital Deaths Due to Coronary Heart Disease in Sweden (1991 to
2006)
Kerstin Dudas, Georg Lappas, S. Stewart, Annika Rosengren
Circulation - 2011-01-01 -
Decreasing trends in the incidence of heart failure after acute myocardial infarction from 1993-2004: a study of 175,216 patients with a first acute myocardial infarction in
Sweden
Masoud Shafazand, Annika Rosengren, Georg Lappas, Karl Swedberg, Maria Schaufelberger
European journal of heart failure - 2011-01-01 -
Intake of Lactobacillus plantarum reduces certain gastrointestinal symptoms during treatment with
antibiotics.
Elisabeth Lönnermark, Vanda Friman, Georg Lappas, Torsten Sandberg, Anna Berggren, Ingegerd Adlerberth
Journal of clinical gastroenterology - 2010-01-01 -
Medication in relation to ST-segment elevation myocardial infarction in patients with a first myocardial infarction: Swedish Register of Information and Knowledge About Swedish Heart Intensive Care Admissions
(RIKS-HIA)
Lena Björck, Lars Wallentin, Ulf Stenestrand, Georg Lappas, Annika Rosengren
Archives of Internal Medicine - 2010-01-01 -
Twenty-year trends in incidence and 1-year mortality in Swedish patients hospitalised with non-AMI chest pain. Data from 1987-2006 from the Swedish hospital and death
registries
Annika Janson Fagring, Georg Lappas, Karin I Kjellgren, Catharina Welin, Karin Manhem, Annika Rosengren
Heart - 2010-01-01 -
Symptoms of a first acute myocardial infarction in women and
men.
Johanna Berg, Kerstin Dudas, Lena Björck, Georg Lappas, Annika Rosengren
Gender medicine : official journal of the Partnership for Gender-Specific Medicine at Columbia University - 2009-01-01 -
Survival trends in men and women with heart failure of ischaemic and non-ischaemic origin: data for the period 1987-2003 from the Swedish Hospital Discharge
Registry
Masoud Shafazand, Maria Schaufelberger, Georg Lappas, Karl Swedberg, Annika Rosengren
European Heart Journal - 2009-01-01 -
Eating patterns and portion size associated with obesity in a Swedish
population.
Christina Berg, Georg Lappas, Alicja Wolk, Elisabeth Strandhagen, Kjell Torén, Annika Rosengren, Dag Thelle, Lauren Lissner
Appetite - 2009-01-01 -
Big men and atrial fibrillation: effects of body size and weight gain on risk of atrial fibrillation in
men.
Annika Rosengren, Paul J Hauptman, Georg Lappas, Lars Olsson, Lars Wilhelmsen, Karl Swedberg
European heart journal - 2009-01-01 -
Modelling the decreasing coronary heart disease mortality in Sweden between 1986 and
2002.
Lena Björck, Annika Rosengren, Kathleen Bennett, Georg Lappas, Simon Capewell
European heart journal - 2009-01-01 -
Systematically missing confounders in individual participant data meta-analysis of observational cohort
studies.
Collaboration Fibrinogen Studies, Annika Rosengren, Lars Wilhelmsen, Georg Lappas, Henry Eriksson
Statistics in medicine - 2009-01-01 -
Food patterns and cardiovascular disease risk factors: the Swedish INTERGENE research
program.
Christina Berg, Georg Lappas, Elisabeth Strandhagen, Alicja Wolk, Kjell Torén, Annika Rosengren, Nibia Aires, Dag Thelle, Lauren Lissner
The American journal of clinical nutrition - 2008-01-01 -
The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular
diseases
Collaboration Emerging Risk Factors, J. Danesh, S. Erqou, M. Walker, S. G. Thompson, R. Tipping, C. Ford, S. Pressel, G. Walldius, I. Jungner, A. R. Folsom, L. E. Chambless, M. Knuiman, P. H. Whincup, S. G. Wannamethee, R. W. Morris, J. Willeit, S. Kiechl, P. Santer, A. Mayr, N. Wald, S. Ebrahim, D. A. Lawlor, J. W. Yarnell, J. Gallacher, E. Casiglia, V. Tikhonoff, P. J. Nietert, S. E. Sutherland, D. L. Bachman, J. E. Keil, M. Cushman, B. M. Psaty, R. P. Tracy, A. Tybjaerg-Hansen, B. G. Nordestgaard, R. Frikke-Schmidt, S. Giampaoli, L. Palmieri, S. Panico, D. Vanuzzo, L. Pilotto, L. Simons, J. McCallum, Y. Friedlander, F. G. Fowkes, A. J. Lee, F. B. Smith, J. Taylor, J. Guralnik, C. Phillips, R. Wallace, D. Blazer, K. T. Khaw, J. H. Jansson, C. Donfrancesco, V. Salomaa, K. Harald, P. Jousilahti, E. Vartiainen, M. Woodward, R. B. D'Agostino, P. A. Wolf, R. S. Vasan, M. J. Pencina, E. M. Bladbjerg, T. Jorgensen, L. Moller, J. Jespersen, R. Dankner, A. Chetrit, F. Lubin, Annika Rosengren, Lars Wilhelmsen, Georg Lappas, Henry Eriksson, Cecilia Björkelund, P. Cremer, D. Nagel, R. Tilvis, T. Strandberg, B. Rodriguez, L. M. Bouter, R. J. Heine, J. M. Dekker, G. Nijpels, C. D. Stehouwer, E. Rimm, J. Pai, S. Sato, H. Iso, A. Kitamura, H. Noda, U. Goldbourt, J. T. Salonen, K. Nyyssonen, T. P. Tuomainen, D. Deeg, J. L. Poppelaars, T. Meade, J. Cooper, B. Hedblad, G. Berglund, G. Engstrom, A. Doring, W. Koenig, C. Meisinger, W. Mraz, L. Kuller, R. Selmer, A. Tverdal, W. Nystad, R. Gillum, M. Mussolino, S. Hankinson, J. Manson, B. De Stavola, C. Knottenbelt, J. A. Cooper, K. A. Bauer, R. D. Rosenberg, Y. Naito, I. Holme, H. Nakagawa, H. Miura, P. Ducimetiere, X. Jouven, C. Crespo, M. Garcia-Palmieri, P. Amouyel, D. Arveiler, A. Evans, J. Ferrieres, H. Schulte, G. Assmann, J. Shepherd, C. Packard, N. Sattar, B. Cantin, B. Lamarche, J. P. Despres, G. R. Dagenais, E. Barrett-Connor, D. Wingard, R. Bettencourt, V. Gudnason, T. Aspelund, G. Sigurdsson, B. Thorsson, M. Trevisan, J. Witteman, I. Kardys, M. Breteler, A. Hofman, H. Tunstall-Pedoe, R. Tavendale, G. D. Lowe, Y. Ben-Shlomo, B. V. Howard, Y. Zhang, L. Best, J. Umans, A. Onat, T. W. Meade, I. Njolstad, E. Mathiesen, M. L. Lochen, T. Wilsgaard, J. M. Gaziano, M. Stampfer, P. Ridker, H. Ulmer, G. Diem, H. Concin, F. Rodeghiero, A. Tosetto, E. Brunner, M. Shipley, J. Buring, S. M. Cobbe, I. Ford, M. Robertson, Y. He, A. M. Ibanez, E. J. Feskens, D. Kromhout, R. Collins, E. Di Angelantonio, S. Kaptoge, S. Lewington, L. Orfei, L. Pennells, P. Perry, K. Ray, N. Sarwar, M. Scherman, A. Thompson, S. Watson, F. Wensley, I. R. White, A. M. Wood
Eur J Epidemiol - 2007-01-01 -
Long-term risk factors for stroke: twenty-eight years of follow-up of 7457 middle-aged men in Goteborg,
Sweden
P. Harmsen, Georg Lappas, Annika Rosengren, Lars Wilhelmsen
Stroke - 2006-01-01 -
Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant
meta-analysis
J. Danesh, S. Lewington, S. G. Thompson, G. D. Lowe, R. Collins, J. B. Kostis, A. C. Wilson, A. R. Folsom, K. Wu, M. Benderly, U. Goldbourt, J. Willeit, S. Kiechl, J. W. Yarnell, P. M. Sweetnam, P. C. Elwood, M. Cushman, B. M. Psaty, R. P. Tracy, A. Tybjaerg-Hansen, F. Haverkate, M. P. de Maat, F. G. Fowkes, A. J. Lee, F. B. Smith, V. Salomaa, K. Harald, R. Rasi, E. Vahtera, P. Jousilahti, J. Pekkanen, R. D'Agostino, W. B. Kannel, P. W. Wilson, G. Tofler, C. L. Arocha-Pinango, A. Rodriguez-Larralde, E. Nagy, M. Mijares, R. Espinosa, E. Rodriquez-Roa, E. Ryder, M. P. Diez-Ewald, G. Campos, V. Fernandez, E. Torres, R. Marchioli, F. Valagussa, Annika Rosengren, L. Wilhelmsen, Georg Lappas, H. Eriksson, P. Cremer, D. Nagel, J. D. Curb, B. Rodriguez, K. Yano, J. T. Salonen, K. Nyyssonen, T. P. Tuomainen, B. Hedblad, P. Lind, H. Loewel, W. Koenig, T. W. Meade, J. A. Cooper, B. De Stavola, C. Knottenbelt, G. J. Miller, K. A. Bauer, R. D. Rosenberg, S. Sato, A. Kitamura, Y. Naito, T. Palosuo, P. Ducimetiere, P. Amouyel, D. Arveiler, A. E. Evans, J. Ferrieres, I. Juhan-Vague, A. Bingham, H. Schulte, G. Assmann, B. Cantin, B. Lamarche, J. P. Despres, G. R. Dagenais, H. Tunstall-Pedoe, M. Woodward, Y. Ben-Shlomo, G. Davey Smith, V. Palmieri, J. L. Yeh, A. Rudnicka, P. Ridker, F. Rodeghiero, A. Tosetto, J. Shepherd, I. Ford, M. Robertson, E. Brunner, M. Shipley, E. J. Feskens, D. Kromhout, A. Dickinson, B. Ireland, K. Juzwishin, S. Kaptoge, A. Memon, N. Sarwar, M. Walker, J. Wheeler, I. White, A. Wood
JAMA - 2005-01-01 -
Trends in overweight and obesity from 1985 to 2002 in Göteborg, West
Sweden.
Christina Berg, Annika Rosengren, N Aires, Georg Lappas, Kjell Torén, Dag Thelle, Lauren Lissner
International journal of obesity (2005) - 2005-01-01 -
Trends in blood lipid levels, blood pressure, alcohol and smoking habits from 1985 to 2002: results from INTERGENE and
GOT-MONICA.
Christina Berg, Lauren Lissner, Nibia Aires, Georg Lappas, Kjell Torén, Lars Wilhelmsen, Annika Rosengren, Dag Thelle
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology - 2005-01-01 -
Considerable disturbances of cardiovascular risk factors in women with diabetes and myocardial
infarction
Annika Dotevall, Lars Wilhelmsen, Georg Lappas, Annika Rosengren
J Diabetes Complications - 2005-01-01 -
Ostomy patients' perceptions of quality of
care.
Eva Persson, Bengt Gustavsson, Anna-Lena Hellström, Georg Lappas, Leif Hultén
Journal of advanced nursing - 2005-01-01 -
Differences between coronary disease and stroke in incidence, case fatality, and risk factors, but few differences in risk factors for fatal and non-fatal
events
Lars Wilhelmsen, Max Köster, Per Harmsen, Georg Lappas
EUROPEAN HEART JOURNAL - 2005-01-01 -
Information to the relatives of people with ostomies: is it satisfactory and
adequate?
Eva Persson, Bengt Gustavsson, Anna-Lena Hellström, Gisela Fridstedt, Georg Lappas, Leif Hultén
Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society / WOCN - 2005-01-01 -
Risk of coronary events by baseline factors during 28 years follow-up and three periods in a random population sample of
men
Lars Wilhelmsen, Georg Lappas, Annika Rosengren
J Intern Med - 2004-01-01 -
Insulin-like growth factor I levels in healthy
adults.
Kerstin Landin-Wilhelmsen, Per-Arne Lundberg, Georg Lappas, Lars Wilhelmsen
Hormone research - 2004-01-01 -
Calcaneal ultrasound measurements are determined by age and physical activity. Studies in two Swedish random population
samples.
Kerstin Landin-Wilhelmsen, S Johansson, Annika Rosengren, Annika Dotevall, Georg Lappas, Bengt-Åke Bengtsson, Lars Wilhelmsen
Journal of internal medicine - 2000-01-01 -
Independent importance of psychosocial factors for prognosis after myocardial
infarction.
Catharina Welin, Georg Lappas, Lars Wilhelmsen
Journal of Internal Medicine - 2000-01-01