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- Brendan Dolan
Brendan Dolan
Forskare
Avd för medicinsk kemi och cellbiologi-
MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn's
disease
Elena Layunta, Sofia Jäverfelt, Fleur van de Koolwijk, Molly Sivertsson, Brendan Dolan, Liisa Arike, Sara Thulin, Bruce A. Vallance, Thaher Pelaseyed
JCI INSIGHT - 2025 -
BPP43_05035 is a Brachyspira pilosicoli cell surface adhesin that weakens the integrity of the epithelial barrier during
infection
Anandi Rajan, Pablo Gallego, Brendan Dolan, Piyush Patel, Chinmay Dwibedi, Ana S. Luis, Sergio Trillo-Muyo, Liisa Arike, Sjoerd van der Post, Magnus Simrén, Thaher Pelaseyed
GUT MICROBES - 2024 -
Clearance of small intestinal crypts involves goblet cell mucus secretion by intracellular granule rupture and enterocyte ion
transport
Brendan Dolan, Anna Ermund, Beatriz Martinez Abad, M Johansson, Gunnar C. Hansson
Science Signaling - 2022 -
Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus
layer
Jack D. A. Sharpen, Brendan Dolan, Elisabeth E. L. Nyström, George M. H. Birchenough, Liisa Arike, Beatriz Martinez Abad, Malin E V Johansson, Gunnar C. Hansson, Christian V Recktenwald
Nature Communications - 2022 -
Mucus threads from surface goblet cells clear particles from the
airways
Anna Ermund, Lauren N Meiss, Brendan Dolan, F. Jaudas, Lars Ewaldsson, A. Bahr, N. Klymiuk, Gunnar C. Hansson
Respiratory Research - 2021 -
IL-22 promotes the formation of a MUC17 glycocalyx barrier in the postnatal small intestine during
weaning
Elena Layunta, Sofia Jäverfelt, Brendan Dolan, Liisa Arike, Thaher Pelaseyed
Cell Reports - 2021 -
Association between Brachyspira and irritable bowel syndrome with
diarrhoea
Karolina S. Jabbar, Brendan Dolan, Lisbeth Eklund, Catharina Wising, Anna Ermund, Åsa Johansson, Hans Törnblom, Magnus Simrén, Gunnar C. Hansson
Gut - 2021 -
The human transmembrane mucin MUC17 responds to TNF alpha by increased presentation at the plasma
membrane
Hannah Schneider, Evelin Berger, Brendan Dolan, Beatriz Martinez Abad, Liisa Arike, Thaher Pelaseyed, Gunnar C. Hansson
Biochemical Journal - 2019 -
The mucus bundles responsible for airway cleaning are retained in cystic fibrosis and by cholinergic
stimulation
Anna Ermund, Lauren N Meiss, Brendan Dolan, A. Bahr, N. Klymiuk, Gunnar C. Hansson
European Respiratory Journal - 2018