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Magnus Simrén
Prodekan
Sahlgrenska akademinProfessor/specialistläkare
Avd för molekylär och klinisk medicinOm Magnus Simrén
Prodekan vid Medicinska Fakulteten vid Göteborgs Universitet. Professor i medicinsk gastroenterologi vid Göteborgs Universitet och Universitetsjukhusöverläkare i medicinsk gastroenterologi & hepatologi vid Medicinkliniken, Sahlgrenska Universitetssjukhuset. Leder en multidisciplinär forskargrupp inom neurogastroenterologi med fokus på patofysiologi vid funktionella mag-tarmsjukdomar i allmänhet och irritable bowel syndrome (IBS) i synnerhet samt behandlingen av dessa sjukdomar.
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Identification of human gut bacteria that produce bioactive serotonin and promote colonic
innervation
Chiara Moretti, Estelle Grasset, Jiaying Zhu, Gaohua Yang, Louise Olofsson, Muhammad Tanweer Khan, Per-Olof Bergh, Jee-Hwan Oh, Annika Lundqvist, Tom van Gils, Manuela Krämer, Lisa Olsson, Piyush Patel, Matthias Georg Mitteregger, Daysi Espinola Monges, Chinmay Dwibedi, Kimberly Krautkramer, Nienke Koopman, Marcus Henricsson, Andrew J. Macpherson, Thue Schwartz, Gianfranco Grompone, Jan-Peter Van Pijkeren, Valentina Tremaroli, Stefan Roos, Magnus Simrén, Fredrik Bäckhed
CELL REPORTS - 2025 -
Dietary intake and quality in irritable bowel syndrome: a comparative study with controls and the association with symptom
severity
Sanna Nybacka, Esther Colomier, Johann P. Hreinsson, Stine Störsrud, Jan Tack, Hans Törnblom, Magnus Simrén
American Journal of Gastroenterology - 2025 -
Global prevalence and gastrointestinal symptom burden of individuals with a history of
cholecystectomy
Bo Konings, Lukas Michaja Balsiger, Johann Hreinsson, Magnus Simrén, Shrikant I. Bangdiwala, Ami D. Sperber, Olafur S. Palsson, Hans Törnblom, Jan F Tack
Gut - 2025 -
Nurse-Administered Gut-Directed Hypnotherapy for Irritable Bowel Syndrome: A Two-Year Follow-Up
Study
Jenny Lövdahl, Michaela Blomqvist-Storm, Olafur S. Palsson, Gisela Ringström, Hans Törnblom, Magnus Simrén, Inês Trindade
United European Gastroenterology Journal - 2025 -
Clinical Practice Updates: AGA Clinical Practice Update on GI Manifestations and Autonomic or Immune Dysfunction in Hypermobile Ehlers-Danlos Syndrome: Expert
Review
Qasim Aziz, Lucinda A. Harris, Brent P. Goodman, Magnus Simrén, Andrea Shin
Clinical Gastroenterology and Hepatology - 2025 -
Intra- and Interobserver Variability of Acute Food–Induced Reactions During Confocal Laser Endomicroscopy: An International Multicenter Validation
Study
Lukas Michaja Balsiger, Tom van Gils, Yaser Hatem, Amanda Blomsten, Karlien Raymenants, Cedric Van de Bruaene, Leila Juvyns, Johann P. Hreinsson, Tim Vanuytsel, Hans Törnblom, Christian Sina, Magnus Simrén, Jan Tack
Neurogastroenterology and Motility - 2025 -
Functional Dyspepsia and Its Subgroups: Prevalence and Impact in the Rome IV Global Epidemiology
Study
Jan Tack, O. S. Palsson, S. I. Bangdiwala, J. Schol, F. Carbone, K. van den Houte, B. Broeders, D. Drossman, D. L. Dumitrascu, X. Fang, S. Fukudo, U. C. Ghoshal, J. Kellow, R. Khatun, E. Okeke, E. M. Quigley, M. Schmulson, Magnus Simrén, W. E. Whitehead, P. Whorwell, A. D. Sperber
ALIMENTARY PHARMACOLOGY & THERAPEUTICS - 2025 -
Gas-Related Symptoms in the General Population: Prevalence, Impact and Associated Factors in a Survey of the United States, the United Kingdom, and
Mexico
Olafur S. Palsson, Douglas A. Drossman, Tack Jan, Boris Le Neve, Laurent Quinquis, Rim Hassouna, Johannah Ruddy, Max J. Schmulson, Carolyn B. Morris, Shrikant I. Bangdiwala, Magnus Simrén
NEUROGASTROENTEROLOGY AND MOTILITY - 2025 -
Disorders of the gut-brain interaction among European people with obesity: Prevalence and burden of compatible
symptoms
Chloe Melchior, Johann P. Hreinsson, Jan Tack, Jutta Keller, Qasim Aziz, Olafur S. Palsson, Shrikant Bangdiwala, Ami D. Sperber, Magnus Simrén, Jean-Marc Sabate
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL - 2025 -
Comparison of the Prevalence of Meal-Related Nausea in Different Functional Dyspepsia
Subgroups
Bert Broeders, Esther Colomier, Florencia Carbone, Magnus Simrén, Tao Bai, Jinsong Liu, Chloe Melchior, Guillaume Gourcerol, Kee-Huat Chuah, Khoo Xin Hui, Sanjiv Mahadeva, Kewin Tien Ho Siah, Kok-Ann Gwee, Peter Liptak, Peter Banovcin, Gerald Holtmann, Natasha Koloski, Marilia Carabotti, Bruno Annibale, Hidekazu Suzuki, Masaya Sano, Takashi Ueda, Hassan Shahoon, Peyman Adibi, Cedric Van de Bruaene, Tim Vanuytsel, Jan Tack
NEUROGASTROENTEROLOGY AND MOTILITY - 2025 -
Gastrointestinal transit abnormalities in irritable bowel syndrome and their relation to
symptoms
Abdulsalam Ibrahim Aliyu, Ryo Katsumata, Hans Törnblom, Magnus Simrén
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY - 2025 -
Results from a psychometric validation study: irritable bowel syndrome patients report higher symptom burden using end-of-day versus real-time
assessment
Michelle Bosman, Lisa Vork, Daisy Jonkers, Johanna Snijkers, Rabia Topan, Qasim Aziz, Irina Midenfjord, Magnus Simrén, Ad Masclee, Daniel Keszthelyi, John Bothmer, Carsten Leue, Joanna Kruimel, Zlatan Mujagic, Sander van Kuijk, Hans Tornblom, Emilio Quetglas
American Journal of Gastroenterology - 2025 -
Elevated Fecal Biomarkers of Colo-Rectal Epithelial Cell Activity in Irritable Bowel
Syndrome
Per Venge, Valeria Castro Tejera, Christer Petersson, Shengyuan Xu, Anders Larsson, Magnus Simrén, Lena Öhman, Hans Törnblom
Neurogastroenterology and Motility - 2025 -
The role of gluten and wheat in irritable bowel syndrome and noncoeliac gluten or wheat
sensitivity
Tom van Gils, Magnus Simrén
CURRENT OPINION IN GASTROENTEROLOGY - 2025 -
Prevalence and Factors Associated With Symptom Profiles of Disorders of Gut-Brain Interaction in Obesity Before and After
Treatment
Esther Colomier, Janita Halminen, Malin Bjorck, Gudrun Hoskuldsdottir, Karin Mossberg, My Engström, Bjoern Eliasson, Ville Wallenius, Lars Fandriks, Jan Tack, Hans Törnblom, Magnus Simrén
NEUROGASTROENTEROLOGY AND MOTILITY - 2025 -
Rome Foundation Working Team Report on overlap in disorders of gut-brain
interaction
Giovanni Barbara, Imran Aziz, Sarah Ballou, Lin Chang, Alexander C. Ford, Shin Fukudo, Samuel Nurko, Carolina Olano, Miguel Saps, Gregory Sayuk, Kewin T. H. Siah, Lukas Van Oudenhove, Magnus Simrén
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY - 2025 -
Rome Foundation Working Team Report: Consensus Statement on the Design and Conduct of Behavioural Clinical Trials for Disorders of Gut-Brain
Interaction
Helen Burton-Murray, Livia Guadagnoli, Kendra Kamp, Ines A. Trindade, Lynda H. Powell, Magnus Simrén, Brjann Ljotsson, Laurie Keefer
ALIMENTARY PHARMACOLOGY & THERAPEUTICS - 2025 -
Clinical Trial: Study to Investigate the Efficacy and Safety of the Alpha-2-Delta Ligand PD-217,014 in Patients With Irritable Bowel
Syndrome
Lesley A. Houghton, Simiao Gao, Steven A. Gilbert, Benoit Coffin, Magnus Simrén, Jeremy D. Gale
ALIMENTARY PHARMACOLOGY & THERAPEUTICS - 2025 -
Factors Associated With Abdominal Pain in Patients With Active and Quiescent Ulcerative Colitis: A Multicohort
Study
Tom van Gils, Hans Törnblom, Johann P. Hreinsson, Borje Jonefjall, Hans Strid, Magnus Simrén
ALIMENTARY PHARMACOLOGY & THERAPEUTICS - 2025 -
BPP43_05035 is a Brachyspira pilosicoli cell surface adhesin that weakens the integrity of the epithelial barrier during
infection
Anandi Rajan, Pablo Gallego, Brendan Dolan, Piyush Patel, Chinmay Dwibedi, Ana S. Luis, Sergio Trillo-Muyo, Liisa Arike, Sjoerd van der Post, Magnus Simrén, Thaher Pelaseyed
GUT MICROBES - 2024 -
Exposure of Colon-Derived Epithelial Monolayers to Fecal Luminal Factors from Patients with Colon Cancer and Ulcerative Colitis Results in Distinct Gene Expression
Patterns
Maria K Magnusson, Anna Bas-Forsberg, Alexandra Verveda, Maria Sapnara, Julie Lorent, Otto Savolainen, Yvonne Wettergren, Hans Strid, Magnus Simrén, Lena Öhman
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2024 -
Effect of Brain-Gut Behavioral Treatments on Abdominal Pain in Irritable Bowel Syndrome: Systematic Review and Network
Meta-Analysis
Vivek C. Goodoory, Mais Khasawneh, Elyse R. Thakur, Hazel A. Everitt, Gregory D. Gudleski, Jeffrey M. Lackner, Rona Moss-Morris, Magnus Simrén, Dipesh H. Vasant, Paul Moayyedi, Christopher J. Black, Alexander C. Ford
GASTROENTEROLOGY - 2024 -
Critical appraisal of the SIBO hypothesis and breath testing: A clinical practice update endorsed by the European society of neurogastroenterology and motility (ESNM) and the American neurogastroenterology and motility society
(ANMS)
Purna Kashyap, Paul Moayyedi, Eamonn M.M. Quigley, Magnus Simrén, Stephen Vanner
Neurogastroenterology and Motility - 2024 -
Diet Options for IBS Other Than the Low-FODMAP
Diet
Magnus Simrén
Gastroenterology and Hepatology - 2024 -
Predictors of symptom trajectory in newly diagnosed ulcerative colitis: a 3-year follow-up cohort
study.
Maaike Van Den Houte, Livia Guadagnoli, Lena Öhman, Anders Bergstedt, Berndt Zeijlemaker Johansson, Magnus Simrén, Hans Strid, Lukas Van Oudenhove, Jan Svedlund
Journal of Crohn's and Colitis - 2024 -
Association Between Celiac Disease and Irritable Bowel Syndrome: A Nationwide Cohort
Study
Karl Mårild, Jonas Söderling, Benjamin Lebwohl, Peter H.R. Green, Hans Törnblom, Magnus Simrén, Kyle Staller, Ola Olén, Jonas F. Ludvigsson
Clinical Gastroenterology and Hepatology - 2024 -
Patients' experiences of dietary changes during a structured dietary intervention for irritable bowel
syndrome
Cecilia Weznaver, Sanna Nybacka, Magnus Simrén, Hans Törnblom, Sofie Jakobsson, Stine Störsrud
JOURNAL OF HUMAN NUTRITION AND DIETETICS - 2024 -
The aging gastrointestinal tract: Epidemiology and clinical significance of disorders of gut-brain interaction in the older general
population
Ami D. Sperber, Tamar Freud, Olafur S. Palsson, Shrikant I. Bangdiwala, Magnus Simrén
ALIMENTARY PHARMACOLOGY & THERAPEUTICS - 2024 -
A low FODMAP diet plus traditional dietary advice versus a low-carbohydrate diet versus pharmacological treatment in irritable bowel syndrome (CARIBS): a single-centre, single-blind, randomised controlled
trial
Sanna Nybacka, Hans Törnblom, Axel Josefsson, Johann P. Hreinsson, Lena Böhn, Åsa Frändemark, Cecilia Weznaver, Stine Störsrud, Magnus Simrén
LANCET GASTROENTEROLOGY & HEPATOLOGY - 2024 -
Coffee, Alcohol, and Artificial Sweeteners Have Temporal Associations with Gastrointestinal
Symptoms
Egbert Clevers, Darren Launders, Damian Helme, Sanna Nybacka, Stine Störsrud, Maura Corsetti, Lukas Van Oudenhove, Magnus Simrén, Jan Tack
DIGESTIVE DISEASES AND SCIENCES - 2024 -
Diarrhoea of unknown cause: medical treatment in a stepwise manner Management of Idiopathic Diarrhoea Based on Experience of Step-Up Medical
Treatment
Ann-Sofie Jansson-Rehnberg, Asbjorn Mohr Drewes, Jon Sponheim, Christer Borgfelt, Andreas Munch, Wilhelm Graf, Magnus Simrén, Greger Lindberg, Per M. Hellstrom
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY - 2024 -
Worldwide population prevalence and impact of sub-diagnostic gastrointestinal
symptoms
Olafur S. Palsson, Jan Tack, Douglas A. Drossman, Boris Le Neve, Laurent Quinquis, Rim Hassouna, Johannah Ruddy, Carolyn B. Morris, Ami D. Sperber, Shrikant I. Bangdiwala, Magnus Simrén
ALIMENTARY PHARMACOLOGY & THERAPEUTICS - 2024 -
Symptom profiles compatible with disorders of gut-brain interaction (DGBI) in organic gastrointestinal diseases: A global population-based
study
Tom van Gils, Johann P. Hreinsson, Hans Törnblom, Jan Tack, Shrikant I. Bangdiwala, Olafur S. Palsson, Ami D. Sperber, Magnus Simrén
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL - 2024 -
Quality of Life and Bidirectional Gut-Brain Interactions in Irritable Bowel Syndrome From Adolescence to
Adulthood
Jessica Sjölund, Inger Kull, Anna Bergström, Brjánn Ljótsson, Hans Törnblom, Ola Olén, Magnus Simrén
Clinical Gastroenterology and Hepatology - 2024 -
Prolonged Gastrointestinal Manifestations After Recovery From
COVID-19
B. Joseph Elmunzer, Olafur S. Palsson, Nauzer Forbes, Ali Zakaria, Christian Davis, Andrew Canakis, Emad Qayed, Benjamin Bick, Swati Pawa, William M. Tierney, Caroline G. McLeod, Jason Taylor, Harsh Patel, Robin B. Mendelsohn, Gokul Bala, Ian Sloan, Ambreen A. Merchant, Zachary L. Smith, Morgan A. Sendzischew Shane, Olga C. Aroniadis, Collins O. Ordiah, Johannah M. Ruddy, Magnus Simrén, Jan Tack, Douglas Drossman
Clinical Gastroenterology and Hepatology - 2024 -
Natural history of symptoms and prognostic information of the rapid drink challenge and solid bolus swallows in esophagogastric junction outflow obstruction defined by
manometry
Axel Josefsson, Magnus Simrén, Adam Smolak, Nour Sabbagh, Hans Törnblom
Neurogastroenterology and Motility - 2024 -
The aging gut: Symptoms compatible with disorders of gut-brain interaction (DGBI) in older adults in the general
population
J. Busby-Whitehead, W. E. Whitehead, A. D. Sperber, O. S. Palsson, Magnus Simrén
Journal of the American Geriatrics Society - 2024 -
Global Prevalence of Psychological Distress and Comorbidity With Disorders of Gut-Brain
Interactions
Inês Trindade, Johann P. Hreinsson, Chloé Melchior, Joost Algera, Esther Colomier, Hans Törnblom, Douglas Drossman, Jan Tack, Olafur S. Palsson, Shrikant I. Bangdiwala, Ami D. Sperber, Magnus Simrén
The American journal of gastroenterology - 2024 -
Temporal stability of fecal metabolomic profiles in irritable bowel
syndrome
Cristina Iribarren, Otto Savolainen, Maria Sapnara, Hans Törnblom, Magnus Simrén, Maria K Magnusson, Lena Öhman
Neurogastroenterology and Motility - 2024 -
Viktigt att stegvis öka insatser vid farmakologisk
diarrébehandling
Ann Sofie Jansson-Rehnberg, Christer Borgfeldt, Andreas Münch, Wilhelm Graf, Magnus Simrén, Greger Lindberg, Per M Hellström
Läkartidningen - 2023 -
Targeting the gut microenvironment in IBS to improve
symptoms
Magnus Simrén
Nature Reviews Gastroenterology and Hepatology - 2023 -
Associations between postprandial symptoms, hydrogen and methane production, and transit time in irritable bowel
syndrome
Joost Algera, Esther Colomier, Chloé Melchior, Johann P. Hreinsson, Irina Midenfjord, Egbert Clevers, Magnus Simrén, Hans Törnblom
Neurogastroenterology and Motility - 2023 -
Placebo response in pharmacological trials in patients with functional dyspepsia-A systematic review and
meta-analysis
M. Bosman, F. Smeets, S. Elsenbruch, J. Tack, Magnus Simrén, N. Talley, B. Winkens, A. Masclee, D. Keszthelyi
Neurogastroenterology and Motility - 2023 -
The influence of muscle performance and fatigue on prognosis in patients with compensated liver
disease
Ulrika Ekerfors, Magnus Simrén, Hanns-Ulrich Marschall, Daghan Demir, Axel Josefsson
BMC Gastroenterology - 2023 -
Mechanisms underlying food-related symptoms in disorders of gut-brain interaction: Course ahead in research and clinical
practice
Esther Colomier, Joost Algera, K. Van den Houte, Magnus Simrén, Jan Tack
Baillière's Best Practice & Research : Clinical Gastroenterology - 2023 -
A comparative study of disorders of gut-brain interaction in Western Europe and Asia based on the Rome foundation global epidemiology
study
Johann P. Hreinsson, R. K. M. Wong, Jan Tack, P. Whorwell, M. A. Benninga, V. Andresen, B. Bonaz, S. C. Choi, E. S. Corazziari, J. Santos, S. Fukudo, M. Kanazawa, X. C. Fang, S. I. Bangdiwala, A. D. Sperber, O. S. Palsson, Magnus Simrén
Neurogastroenterology and Motility - 2023 -
Factor Analysis of the Rome IV Criteria for Major Disorders of Gut-Brain Interaction (DGBI) Globally and Across Geographical, Sex, and Age
Groups
J. P. Hreinsson, Hans Törnblom, Jan Tack, D. A. Drossman, W. E. Whitehead, S. I. Bangdiwala, A. D. Sperber, O. S. Palsson, Magnus Simrén
Gastroenterology - 2023 -
Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new independent
variants
S. Alemany, M. Soler-Artigas, J. Cabana-Dominguez, D. Fakhreddine, N. Llonga, L. Vilar-Ribo, A. Rodriguez-Urrutia, J. Palacio, A. M. Gonzalez-Castro, B. Lobo, C. Alonso-Cotoner, Magnus Simrén, J. Santos, J. A. Ramos-Quiroga, M. Ribases
Journal of Translational Medicine - 2023 -
Epidemiology of disorders of gut-brain interaction in Belgium and differences between two language groups: Results from the Rome foundation global epidemiology
study
B. Broeders, E. Devolder, M. Jones, Magnus Simrén, S. I. Bangdiwala, A. D. Sperber, O. S. Palsson, J. Tack
Neurogastroenterology and Motility - 2023 -
Prevalence and impact of disorders of Gut-Brain interaction in
Sweden
Navkiran Thind Tornkvist, Magnus Simrén, Johann P. Hreinsson, Jan Tack, S. I. Bangdiwala, A. D. Sperber, O. S. Palsson, Axel Josefsson, Hans Törnblom
Neurogastroenterology and Motility - 2023
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