Martin Adiels
About Martin Adiels
Martin’s research is focused on development and implementation of mathematical models that describes human lipid metabolism. In particular how the dynamics of blood lipids is altered in disease states related to cardiovascular diseases. The use of mathematical models allows for indirectly measuring otherwise inaccessible fluxes. Martin is collaborating with several national and international clinical research groups. Martin is also interested in how individual and population based data should best used in order to improve model parameter estimates.
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Prepregnancy overweight and obesity and long-term risk of venous thromboembolism in
women.
Ahmad Mahmoud, Katarina Glise Sandblad, Christina E Lundberg, Gustaf Hellsén, Per-Olof Hansson, Martin Adiels, Annika Rosengren
Scientific reports - 2023 -
Pulmonary embolism and deep venous thrombosis after COVID-19: long-term risk in a population-based cohort
study
H. Sjoland, Martin Lindgren, Triantafyllia Toska, Per-Olof Hansson, Katarina Glise Sandblad, C. Alex, Lena Björck, Ottmar Cronie, J. Bjork, Christina Lundberg, Martin Adiels, Annika Rosengren
Research and Practice in Thrombosis and Haemostasis - 2023 -
Triglyceride-rich lipoprotein remnants, low-density lipoproteins, and risk of coronary heart disease: a UK Biobank
study
Elias Björnson, Martin Adiels, M. R. Taskinen, S. Burgess, Aidin Rawshani, Jan Borén, C. J. Packard
European Heart Journal - 2023 -
Mediating role of atherogenic lipoproteins in the relationship between liver fat and coronary artery
calcification
Elias Björnson, Dimitrios Samaras, Martin Adiels, J. Kullberg, Fredrik Bäckhed, Göran Bergström, Anders Gummesson
Scientific Reports - 2023 -
Age and sex differences in cause-specific excess mortality and years of life lost associated with COVID-19 infection in the Swedish
population
Christina Lundberg, Ailiana Santosa, J. Bjork, M. Branden, Ottmar Cronie, Martin Lindgren, Jon Edqvist, Maria A I Åberg, Martin Adiels, Annika Rosengren
European Journal of Public Health - 2023 -
Severe COVID-19 Infection in Type 1 and Type 2 Diabetes During the First Three Waves in
Sweden.
Jon Edqvist, Christina Lundberg, Karin Andréasson , Lena Björck, Pigi Dikaiou, Johnny Ludvigsson, Marcus Lind, Martin Adiels, Annika Rosengren
Diabetes care - 2023 -
Pre-diabetes is associated with attenuation rather than volume of epicardial adipose tissue on computed
tomography
David Molnar, Elias Björnson, M. Larsson, Martin Adiels, Anders Gummesson, Fredrik Bäckhed, Ola Hjelmgren, Göran Bergström
Scientific Reports - 2023 -
Risk of Myocardial Infarction, Ischemic Stroke, and Mortality in Patients Who Undergo Gastric Bypass for Obesity Compared With Non-Operated Obese Patients and Population
Controls.
Christina Lundberg, Lena Björck, Martin Adiels, Jesper Lagergren, Annika Rosengren
Annals of surgery - 2023 -
COVID-19 in people aged 18-64 in Sweden in the first year of the pandemic: Key factors for severe disease and
death.
Annika Rosengren, Mia Söderberg, Christina Lundberg, Martin Lindgren, Ailiana Santosa, Jon Edqvist, Maria A I Åberg, Magnus Gisslén, Josefina Robertson, Ottmar Cronie, Naveed Sattar, Jesper Lagergren, Maria Brandén, Jonas Björk, Martin Adiels
Global epidemiology - 2022 -
BMI in early adulthood is associated with severe COVID-19 later in life: A prospective cohort study of 1.5 million Swedish
men
Josefina Robertson, Martin Adiels, Lauren Lissner, Kirsten Mehlig, Agnes af Geijerstam, Martin Lindgren, Magnus Gisslén, E. E. Bak, Annika Rosengren, Maria A I Åberg
Obesity - 2022 -
Severe COVID-19 in people 55 and older during the first year of the pandemic in
Sweden
Annika Rosengren, Christina Lundberg, Mia Söderberg, Ailiana Santosa, Jon Edqvist, Martin Lindgren, Maria A I Åberg, Magnus Gisslén, Josefina Robertson, Ottmar Cronie, Naveed Sattar, J. Lagergren, M. Branden, J. Bjork, Martin Adiels
Journal of Internal Medicine - 2022 -
Corrigendum to "Effects of exercise on symptoms of anxiety in primary care patients: A randomized controlled trial", published online ahead of print as J Affect Disord. 2021 Oct
10;297:26-34.
Malin Henriksson, Alexander Wall, Jenny Nyberg, Martin Adiels, Karin Lundin, Ylva Bergh, Robert Eggertsen, Louise Danielsson, Hans-Georg Kuhn, Maria Westerlund, N David Åberg, Margda Waern, Maria A I Åberg
Journal of affective disorders - 2022 -
Postprandial metabolism of apolipoproteins B48, B100, C-III, and E in humans with APOC3 loss-of-function
mutations
M. R. Taskinen, Elias Björnson, N. Matikainen, S. Soderlund, J. Ramo, M. M. Ainola, A. Hakkarainen, C. Sihlbom, A. Thorsell, Linda Andersson, Per-Olof Bergh, Marcus Henricsson, Stefano Romeo, Martin Adiels, S. Ripatti, M. Laakso, C. J. Packard, Jan Borén
Jci Insight - 2022 -
Role of endogenous incretins in the regulation of postprandial lipoprotein
metabolism
M. R. Taskinen, N. Matikainen, Elias Björnson, S. Soderlund, M. Ainola, A. Hakkarainen, N. Lundbom, Carina Sihlbom, Annika Thorsell, Linda Andersson, Martin Adiels, B. Hartmann, C. F. Deacon, J. J. Holst, C. J. Packard, Jan Borén
European Journal of Endocrinology - 2022 -
The influence of overcrowding and socioeconomy on the spatio-temporal spread of COVID-19 - a Swedish register
study
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Surgical treatment of obesity and excess risk of developing heart failure in a controlled cohort
study
Christina Lundberg, Shabbar Jamaly, Martin Adiels, J. Lagergren, Carl Johan Svensson, Lena Björck, Annika Rosengren
Esc Heart Failure - 2022 -
Body mass index in adolescence, risk of type 2 diabetes and associated complications: A nationwide cohort study of
men
Karin Andréasson , Jon Edqvist, Martin Adiels, Lena Björck, Martin Lindgren, S. Naveed, Marcus Lind, Maria A I Åberg, Annika Rosengren
EClinicalMedicine - 2022 -
BMI, sex and outcomes in hospitalised patients in western Sweden during the COVID-19
pandemic
Martin Lindgren, Triantafyllia Toska, C. Alex, Christina Lundberg, Ottmar Cronie, Annika Rosengren, Martin Adiels, Helen Sjöland
Scientific Reports - 2022 -
Effects of exercise on symptoms of anxiety in primary care patients: A randomized controlled
trial.
Malin Henriksson, Alexander Wall, Jenny Nyberg, Martin Adiels, Karin Lundin, Ylva Bergh, Robert Eggertsen, Louise Danielsson, Hans-Georg Kuhn, Maria Westerlund, N David Åberg, Margda Waern, Maria A I Åberg
Journal of affective disorders - 2022 -
Effects of pnpla3 i148m on hepatic lipid and very low-density lipoprotein metabolism in
humans.
Jan Borén, Martin Adiels, Elias Björnson, Niina Matikainen, Sanni Söderlund, Joel Rämö, Marcus Ståhlman, Pietari Ripatti, Samuli Ripatti, Aarno Palotie, Rosellina Margherita Mancina, Mari Ainola, Antti Hakkarainen, Stefano Romeo, Chris J Packard, Marja-Riitta Taskinen
Journal of internal medicine - 2022 -
Diverging trends for onset of acute myocardial infarction, heart failure, stroke and mortality in young males: role of changes in obesity and
fitness
N David Åberg, Martin Adiels, Martin Lindgren, Jenny Nyberg, Hans-Georg Kuhn, Josefina Robertson, Maria Schaufelberger, Naveed Sattar, Maria A I Åberg, Annika Rosengren
Journal of Internal Medicine - 2021 -
Effects of Evolocumab on the Postprandial Kinetics of Apo (Apolipoprotein) B100- and B48-Containing Lipoproteins in Subjects With Type 2
Diabetes.
Marja-Riitta Taskinen, Elias Björnson, Juhani Kahri, Sanni Söderlund, Niina Matikainen, Kimmo Porthan, Mari Ainola, Antti Hakkarainen, Nina Lundbom, Valentina Fermanelli, Johannes Fuchs, Annika Thorsell, Florian Kronenberg, Linda Andersson, Martin Adiels, Chris J Packard, Jan Borén
Arteriosclerosis, thrombosis, and vascular biology - 2021 -
Prevalence of Subclinical Coronary Artery Atherosclerosis in the General
Population.
Göran Bergström, Margaretha Persson, Martin Adiels, Elias Björnson, Carl Bonander, Håkan Ahlström, Joakim Alfredsson, Oskar Angerås, Göran Berglund, Anders Blomberg, John Brandberg, Mats Börjesson, Kerstin Cederlund, Ulf de Faire, Olov Duvernoy, Örjan Ekblom, Gunnar Engström, Jan E Engvall, Erika Fagman, Mats Eriksson, David Erlinge, Björn Fagerberg, Agneta Flinck, Isabel Goncalves, Emil Hagström, Ola Hjelmgren, Lars Lind, Eva Lindberg, Per Lindqvist, Johan Ljungberg, Martin Magnusson, Maria Mannila, Hanna Markstad, Moman A Mohammad, Fredrik H Nyström, Ellen Ostenfeld, Anders Persson, Annika Rosengren, Anette Sandström, Anders Själander, Magnus C Sköld, Johan Sundström, Eva Swahn, Stefan Söderberg, Kjell Torén, Carl Johan Östgren, Tomas Jernberg
Circulation - 2021 -
Glucosylceramide synthase deficiency in the heart compromises β1-adrenergic receptor
trafficking.
Linda Andersson, Mathieu Cinato, Ismena Mardani, Azra Miljanovic, Arif Mohammed, Ara Koh, Malin Lindbom, Marion Laudette, Entela Bollano, Elmir Omerovic, Martina Klevstig, Marcus Henricsson, Per Fogelstrand, Karl Swärd, Matias Ekstrand, Max Levin, Johannes Wikström, Stephen Doran, Tuulia Hyötyläinen, Lisanna Sinisalu, Matej Oresic, Åsa Tivesten, Martin Adiels, Martin O Bergo, Richard Proia, Adil Mardinoglu, Anders Jeppsson, Jan Borén, Malin Levin
European heart journal - 2021 -
Atrial fibrillation and risk of venous thromboembolism: a Swedish Nationwide Registry
Study.
Björn Hornestam, Martin Adiels, Kok Wai Giang, Per-Olof Hansson, Lena Björck, Annika Rosengren
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology - 2021 -
Fitness, strength and severity of COVID-19: a prospective register study of 1 559 187 Swedish
conscripts
Agnes af Geijerstam, Kirsten Mehlig, Mats Börjesson, Josefina Robertson, Jenny Nyberg, Martin Adiels, Annika Rosengren, Maria A I Åberg, Lauren Lissner
BMJ Open - 2021 -
Effects of liraglutide on the metabolism of triglyceride-rich lipoproteins in type 2
diabetes
M. R. Taskinen, Elias Björnson, N. Matikainen, S. Soderlund, K. H. Pietilainen, M. Ainola, A. Hakkarainen, N. Lundbom, Johannes Fuchs, Annika Thorsell, Linda Andersson, Martin Adiels, C. J. Packard, Jan Borén
Diabetes Obesity & Metabolism - 2021 -
Trajectories in HbA1c and other risk factors among adults with type 1 diabetes by age at
onset
Jon Edqvist, Araz Rawshani, Aidin Rawshani, Martin Adiels, S. Franzén, Lena Björck, A. M. Svensson, Marcus Lind, N. Sattar, Annika Rosengren
BMJ Open Diabetes Research and Care - 2021 -
Severe COVID-19 in people with type 1 and type 2 diabetes in Sweden: A nationwide retrospective cohort
study.
Aidin Rawshani, Elin Allansson Kjölhede, Araz Rawshani, Naveed Sattar, Katarina Eeg-Olofsson, Martin Adiels, Johnny Ludvigsson, Marcus Lind, Magnus Gisslén, Eva Hagberg, Georg Lappas, Björn Eliasson, Annika Rosengren
The Lancet regional health. Europe - 2021 -
Obesity, overweight and risk for cardiovascular disease and mortality in young
women
Pigi Dikaiou, Lena Björck, Martin Adiels, Christina Lundberg, Zacharias Mandalenakis, Karin Manhem, Annika Rosengren
European Journal of Preventive Cardiology - 2021 -
Longitudinal plasma protein profiling of newly diagnosed type 2
diabetes.
Anders Gummesson, Elias Björnson, Linn Fagerberg, Wen Zhong, Abdellah Tebani, Fredrik Edfors, Caroline Schmidt, Annika Lundqvist, Martin Adiels, Fredrik Bäckhed, Jochen M Schwenk, Per-Anders Jansson, Mathias Uhlén, Göran Bergström
EBioMedicine - 2021 -
Association between inflammatory response and outcome after subarachnoid
haemorrhage.
Sandra Bjerkne Wenneberg, Helena Odenstedt Hergès, Pernilla Svedin, Carina Mallard, Thomas Karlsson, Martin Adiels, Silvana Naredi, Linda Block
Acta neurologica Scandinavica - 2021 -
Obesity in adolescent men increases the risk of venous thromboembolism in adult
life
Katarina Glise Sandblad, Sverker Jern, Maria A I Åberg, Josefina Robertson, Kjell Torén, Martin Lindgren, Martin Adiels, Per-Olof Hansson, Annika Rosengren
Journal of Internal Medicine - 2020 -
The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver
disease.
Cheng Zhang, Elias Björnson, Muhammad Arif, Abdellah Tebani, Alen Lovric, Rui Benfeitas, Mehmet Ozcan, Kajetan Juszczak, Woonghee Kim, Jung Tae Kim, Gholamreza Bidkhori, Marcus Ståhlman, Per-Olof Bergh, Martin Adiels, Hasan Turkez, Marja-Riitta Taskinen, Jim Bosley, Hanns-Ulrich Marschall, Jens Nielsen, Mathias Uhlén, Jan Borén, Adil Mardinoglu
Molecular systems biology - 2020 -
Effects of TM6SF2 E167K on hepatic lipid and very low-density lipoprotein metabolism in
humans.
Jan Borén, Martin Adiels, Elias Björnson, Nina Matikainen, Sanni Söderlund, Joel T Rämo, Marcus Ståhlman, Puetaru Ripatti, Samuli Ripatti, Aarno Palotie, Rosellina Margherita Mancina, Antti Hakkarainen, Stefano Romeo, Chris j Packard, Marja-Riitta Taskinen
JCI insight - 2020 -
Elevated resting heart rate in adolescent men and risk of heart failure and
cardiomyopathy.
Martin Lindgren, Josefina Robertson, Martin Adiels, Maria Schaufelberger, Maria A I Åberg, Kjell Torén, Margda Waern, N David Åberg, Annika Rosengren
ESC heart failure - 2020 -
Apolipoprotein B48 metabolism in chylomicrons and very low-density lipoproteins and its role in triglyceride transport in normo- and hypertriglyceridemic human
subjects
Elias Björnson, C. J. Packard, Martin Adiels, Linda Andersson, N. Matikainen, S. Soderlund, J. Kahri, A. Hakkarainen, N. Lundbom, J. Lundbom, Carina Sihlbom, Annika Thorsell, H. Zhou, M. R. Taskinen, Jan Borén
Journal of Internal Medicine - 2020 -
Lipid profiling of human diabetic myocardium reveals differences in triglyceride fatty acyl chain length and degree of
saturation.
Elias Björnson, Ylva Östlund, Marcus Ståhlman, Martin Adiels, Elmir Omerovic, Anders Jeppsson, Jan Borén, Malin Levin
International journal of cardiology - 2020 -
Body mass index in women aged 18 to 45 and subsequent risk of heart
failure.
Lena Björck, Christina Lundberg, Maria Schaufelberger, Lauren Lissner, Martin Adiels, Annika Rosengren
European journal of preventive cardiology - 2020 -
Impact of proprotein convertase subtilisin/kexin type 9 inhibition with evolocumab on the postprandial responses of triglyceride-rich lipoproteins in type II diabetic
subjects
M. R. Taskinen, Elias Björnson, Linda Andersson, J. Kahri, K. Porthan, N. Matikainen, S. Soderlund, K. Pietilainen, A. Hakkarainen, N. Lundbom, R. Nilsson, Marcus Ståhlman, Martin Adiels, P. Parini, C. Packard, Jan Borén
Journal of Clinical Lipidology - 2020 -
Body Mass Index in Young Women and Risk of Cardiomyopathy: A Long-Term Follow-Up Study in
Sweden
Josefina Robertson, Martin Lindgren, Maria Schaufelberger, Martin Adiels, Lena Björck, Christina Lundberg, Naveed Sattar, Annika Rosengren, Maria A I Åberg
Circulation - 2020 -
Contrasting Associations of Body Mass Index and Hemoglobin A1c on the Excess Risk of Acute Myocardial Infarction and Heart Failure in Type 2 Diabetes
Mellitus.
Jon Edqvist, Araz Rawshani, Martin Adiels, Lena Björck, Marcus Lind, Ann-Marie Svensson, Soffia Gudbjörnsdottir, Naveed Sattar, Annika Rosengren
Journal of the American Heart Association - 2019 -
BMI, Mortality, and Cardiovascular Outcomes in Type 1 Diabetes: Findings Against an Obesity
Paradox
Jon Edqvist, Araz Rawshani, Martin Adiels, Lena Björck, Marcus Lind, A. M. Svensson, S. Gudbjornsdottir, N. Sattar, Annika Rosengren
Diabetes Care - 2019 -
Investigation of human apoB48 metabolism using a new, integrated non-steady-state model of apoB48 and apoB100
kinetics
Elias Björnson, C. J. Packard, Martin Adiels, Linda Andersson, N. Matikainen, S. Soderlund, J. Kahri, Carina Sihlbom, Annika Thorsell, H. Zhou, M. R. Taskinen, Jan Borén
Journal of Internal Medicine - 2019 -
Higher Body Mass Index in Adolescence Predicts Cardiomyopathy Risk in Midlife Long-Term Follow-Up Among Swedish
Men
Josefina Robertson, Maria Schaufelberger, Martin Lindgren, Martin Adiels, Linus Schiöler, Kjell Torén, J. McMurray, N. Sattar, Maria A I Åberg, Annika Rosengren
Circulation - 2019 -
Role of apolipoprotein C-III overproduction in diabetic
dyslipidaemia
Martin Adiels, M. R. Taskinen, Elias Björnson, Linda Andersson, N. Matikainen, S. Söderlund, J. Kahri, A. Hakkarainen, N. Lundbom, Carina Sihlbom, Annika Thorsell, H. Zhou, K. H. Pietiläinen, C. Packard, Jan Borén
Diabetes, obesity and metabolism - 2019 -
BMI and Mortality in Patients With New-Onset Type 2 Diabetes: A Comparison With Age- and Sex-Matched Control Subjects From the General
Population
Jon Edqvist, Araz Rawshani, Martin Adiels, Lena Björck, Marcus Lind, A. M. Svensson, S. Gudbjornsdottir, N. Sattar, Annika Rosengren
Diabetes Care - 2018 -
Excess risk of hospitalisation for heart failure among people with type 2
diabetes
Annika Rosengren, Jon Edqvist, Araz Rawshani, N. Sattar, S. Franzen, Martin Adiels, A. M. Svensson, Marcus Lind, Soffia Gudbjörnsdottir
Diabetologia - 2018 -
Resting heart rate in late adolescence and long term risk of cardiovascular disease in Swedish
men
Martin Lindgren, Josefina Robertson, Martin Adiels, Maria Schaufelberger, Maria A I Åberg, Kjell Torén, Margda Waern, N David Åberg, Annika Rosengren
International Journal of Cardiology - 2018 -
Young women, body size and risk of atrial
fibrillation.
Christina Persson, Martin Adiels, Lena Björck, Annika Rosengren
European journal of preventive cardiology - 2018 -
Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing-remitting
MS
Lenka Novakova, Avadhesh Kumar Singh, Markus Axelsson, Marcus Ståhlman, Martin Adiels, Clas Malmeström, Henrik Zetterberg, Jan Borén, Jan Lycke, Susanna Cardell, Maria K. Blomqvist
Journal of Neurochemistry - 2018 -
Niacin action in the atherogenic mixed dyslipidemia of metabolic syndrome: Insights from metabolic biomarker profiling and network
analysis
Martin Adiels, M. J. Chapman, P. Robillard, M. Krempf, M. Laville, Jan Borén, Grp Niacin Study
Journal of Clinical Lipidology - 2018 -
Primary aldosteronism and thyroid disorders in atrial fibrillation: A Swedish nationwide case-control
study
Georgios Mourtzinis, Samuel Adamsson Eryd, Annika Rosengren, Lena Björck, Martin Adiels, Gudmundur Johannsson, Karin Manhem
European Journal of Preventive Cardiology - 2018 -
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in
Humans
A. Mardinoglu, Hao Wu, Elias Björnson, C. Zhang, A. Hakkarainen, S. M. Rasanen, S. Lee, Rosellina Margherita Mancina, Mattias Bergentall, K. H. Pietilainen, S. Soderlund, N. Matikainen, Marcus Ståhlman, Per-Olof Bergh, Martin Adiels, B. D. Piening, M. Graner, N. Lundbom, Kevin Jon Williams, Stefano Romeo, J. Nielsen, M. Snyder, M. Uhlen, Göran Bergström, Rosie Perkins, Hanns-Ulrich Marschall, Fredrik Bäckhed, M. R. Taskinen, Jan Borén
Cell Metabolism - 2018 -
An evaluation of the performance of SCORE Sweden 2015 in estimating cardiovascular risk: The Northern Sweden MONICA Study
1999-2014
T. Karjalainen, Martin Adiels, Lena Björck, M. T. Cooney, I. Graham, J. Perk, Annika Rosengren, S. Soderberg, M. Eliasson
European journal of preventive cardiology - 2017 -
Deficiency in perilipin 5 reduces mitochondrial function and membrane depolarization in mouse
hearts.
Linda Andersson, Christina Drevinge, Ismena Mardani, Knut T Dalen, Marcus Ståhlman, Martina Klevstig, Annika Lundqvist, Fred Haugen, Martin Adiels, Per Fogelstrand, Jorge Asin-Cayuela, Lillemor Mattsson Hultén, Max Levin, Ewa Ehrenborg, Yun K Lee, Alan R Kimmel, Jan Borén, Malin Levin
The international journal of biochemistry & cell biology - 2017 -
Long-term trends in the prevalence of patients hospitalized with ischemic stroke from 1995 to 2010 in
Sweden
Kok Wai Giang, Zacharias Mandalenakis, Susanne Nielsen, Lena Björck, Georg Lappas, Martin Adiels, Christina Jern, Annika Rosengren
Plos One - 2017 -
Personal model-assisted identification of NAD(+) and glutathione metabolism as intervention target in
NAFLD
A. Mardinoglu, Elias Björnson, C. Zhang, Martina Klevstig, S. Soderlund, Marcus Ståhlman, Martin Adiels, A. Hakkarainen, N. Lundbom, M. Kilicarslan, B. M. Hallstrom, J. Lundbom, B. Verges, P. H. R. Barrett, G. F. Watts, M. J. Serlie, J. Nielsen, M. Uhlen, Ulf Smith, Hanns-Ulrich Marschall, M. R. Taskinen, Jan Borén
Molecular Systems Biology - 2017 -
Kinetics of plasma triglycerides in abdominal
obesity.
Elias Björnson, Martin Adiels, Marja-Riitta Taskinen, Jan Borén
Current opinion in lipidology - 2017 -
Triglyceride-rich lipoprotein metabolism in women: roles of apoC-II and
apoC-III
E. M. Ooi, D. C. Chan, L. Hodson, Martin Adiels, Jan Borén, F. Karpe, B. A. Fielding, G. F. Watts, P. H. R. Barrett
European Journal of Clinical Investigation - 2016 -
ApoA-II HDL Catabolism and Its Relationships With the Kinetics of ApoA-I HDL and of VLDL1, in Abdominal
Obesity.
Bruno Vergès, Martin Adiels, Jan Borén, Peter Hugh Barrett, Gerald F Watts, Dick Chan, Laurence Duvillard, Sanni Söderlund, Niina Matikainen, Juhani Kahri, Nina Lundbom, Jesper Lundbom, Antti Hakkarainen, Serge Aho, Isabelle Simoneau-Robin, Marja-Riitta Taskinen
The Journal of clinical endocrinology and metabolism - 2016 -
Metabolic transformations of dietary polyphenols: comparison between in vitro colonic and hepatic models and in vivo urinary
metabolites.
Claudia Vetrani, Angela A Rivellese, Giovanni Annuzzi, Martin Adiels, Jan Borén, Ismo Mattila, Matej Orešič, Anna-Marja Aura
The Journal of nutritional biochemistry - 2016 -
Changes in Dietary Fat Intake and Projections for Coronary Heart Disease Mortality in Sweden: A Simulation
Study
Lena Björck, Annika Rosengren, Anna Winkvist, S. Capewell, Martin Adiels, P. Bandosz, J. Critchley, K. Boman, M. Guzman-Castillo, M. O'Flaherty, I. Johansson
PloS one - 2016 -
Targeting acid sphingomyelinase reduces cardiac ceramide accumulation in the post-ischemic
heart
Martina Klevstig, Marcus Ståhlman, Annika Lundqvist, Margareta Scharin Täng, Per Fogelstrand, Martin Adiels, Linda Andersson, R. Kolesnick, Anders Jeppsson, Jan Borén, Malin Levin
Journal of Molecular and Cellular Cardiology - 2016 -
Perilipin 5 is protective in the ischemic
heart
Christina Drevinge, K. T. Dalen, M. N. Mannila, Margareta Scharin Täng, Marcus Ståhlman, Martina Klevstig, Annika Lundqvist, Ismena Mardani, F. Haugen, Per Fogelstrand, Martin Adiels, Jorge Asin-Cayuela, C. Ekestam, J. R. Gadin, Y. K. Lee, H. Nebb, Sara Svedlund, Bengt R Johansson, Lillemor Mattsson Hultén, Stefano Romeo, Björn Redfors, Elmir Omerovic, Max Levin, Li-Ming Gan, P. Eriksson, Linda Andersson, E. Ehrenborg, A. R. Kimmel, Jan Borén, Malin Levin
International Journal of Cardiology - 2016 -
Imaging of Intracellular and Extracellular ROS Levels in Atherosclerotic Mouse Aortas Ex Vivo: Effects of Lipid Lowering by Diet or
Atorvastatin
Matias Ekstrand, Maria Gustafsson Trajkovska, Jeanna Perman Sundelin, Per Fogelstrand, Martin Adiels, M. Johansson, Lillemor Mattsson Hultén, Jan Borén, Max Levin
Plos One - 2015 -
Prognostic Significance of Resting Heart Rate and Use of beta-Blockers in Atrial Fibrillation and Sinus Rhythm in Patients With Heart Failure and Reduced Ejection Fraction: Findings From the Swedish Heart Failure
Registry
S. J. Li, U. Sartipy, L. H. Lund, U. Dahlstrom, Martin Adiels, Max Petzold, Michael Fu
Circulation. Heart failure - 2015 -
Kinetic Studies to Elucidate Impaired Metabolism of Triglyceride-rich Lipoproteins in
Humans.
Martin Adiels, Adil Mardinoglu, Marja-Riitta Taskinen, Jan Borén
Frontiers in Physiology - 2015 -
Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in
Women
L. Hodson, R. Banerjee, B. Rial, W. Arlt, Martin Adiels, Jan Borén, K. Marinou, C. Fisher, I. L. Mostad, I. M. Stratton, P. H. R. Barrett, D. C. Chan, G. F. Watts, K. Harnden, F. Karpe, B. A. Fielding
Journal of the American Heart Association - 2015 -
Improved Estimation of Human Lipoprotein Kinetics with Mixed Effects
Models
Martin Berglund, Martin Adiels, M. R. Taskinen, Jan Borén, Bernt Wennberg
PLoS ONE - 2015 -
Kinetic and Related Determinants of Plasma Triglyceride Concentration in Abdominal Obesity Multicenter Tracer Kinetic
Study
Jan Borén, G. F. Watts, Martin Adiels, S. Soderlund, D. C. Chan, A. Hakkarainen, N. Lundbom, N. Matikainen, J. Kahri, B. Verges, P. H. R. Barrett, M. R. Taskinen
Arteriosclerosis Thrombosis and Vascular Biology - 2015 -
Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial
State
F. L. P. Sips, E. Nyman, Martin Adiels, P. A. J. Hilbers, P. Stralfors, N. A. W. van Riel, G. Cedersund
Plos One - 2015 -
Lipid metabolism in metabolic
syndrome
Jan Borén, Martin Adiels
A Systems Biology Approach to Study Metabolic Syndrome - 2014 -
Interrelationships Between the Kinetics of VLDL Subspecies and HDL Catabolism in Abdominal Obesity: A Multicenter Tracer Kinetic
Study
B. Verges, Martin Adiels, Jan Borén, P. H. Barrett, G. F. Watts, D. Chan, L. Duvillard, S. Soderlund, N. Matikainen, J. Kahri, I. Robin, M. R. Taskinen
Journal of Clinical Endocrinology & Metabolism - 2014 -
Dietary Medium Chain Fatty Acid Supplementation Leads to Reduced VLDL Lipolysis and Uptake Rates in Comparison to Linoleic Acid
Supplementation
D. B. van Schalkwijk, W. J. Pasman, H. F. J. Hendriks, E. R. Verheij, C. M. Rubingh, K. van Bochove, W. H. J. Vaes, Martin Adiels, A. P. Freidig, A. A. de Graaf
PLoS ONE - 2014 -
Inhibition of MAPK Hog1 Results in Increased Hsp104 Aggregate Formation Probably through Elevated Arsenite Influx into the Cells, an Approach with Numerous Potential
Applications
Doryaneh Ahmadpour, Amin Abbaszadehbanaeiyan, Morten Grøtli, Martin Adiels, Mattias Goksör, Caroline B. Adiels
American Journal of Molecular Biology - 2014 -
Hepatic Lipogenesis and a Marker of Hepatic Lipid Oxidation, Predict Postprandial Responses of Triglyceride-rich
Lipoproteins
N. Matikainen, Martin Adiels, S. Soderlund, S. Stennabb, T. Ahola, A. Hakkarainen, Jan Borén, M. R. Taskinen
Obesity - 2014 -
Postprandial hypertriglyceridemia as a coronary risk
factor.
Jan Borén, Niina Matikainen, Martin Adiels, Marja-Riitta Taskinen
Clinica chimica acta; international journal of clinical chemistry - 2014 -
A continuous-time adaptive particle filter for estimations under measurement time uncertainties with an application to a plasma-leucine mixed effects
model.
Annette Krengel, Jan Hauth, Marja-Riitta Taskinen, Martin Adiels, Mats Jirstrand
BMC systems biology - 2013 -
Genetic Variation in SULF2 Is Associated with Postprandial Clearance of Triglyceride-Rich Remnant Particles and Triglyceride Levels in Healthy
Subjects.
Niina Matikainen, Maria Antonella Burza, Stefano Romeo, Antti Hakkarainen, Martin Adiels, Lasse Folkersen, Per Eriksson, Nina Lundbom, Ewa Ehrenborg, Marju Orho-Melander, Marja-Riitta Taskinen, Jan Borén
PloS one - 2013 -
Cardiac steatosis associates with visceral obesity in nondiabetic obese
men.
Marit Granér, Reijo Siren, Kristofer Nyman, Jesper Lundbom, Antti Hakkarainen, Markku O Pentikäinen, Kirsi Lauerma, Nina Lundbom, Martin Adiels, Markku S Nieminen, Marja-Riitta Taskinen
The Journal of clinical endocrinology and metabolism - 2013 -
Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: Impact on small HDL
particles
Marcus Ståhlman, Björn Fagerberg, Martin Adiels, K. Ekroos, J. M. Chapman, A. Kontush, Jan Borén
Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids - 2013 -
Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in
vitro
Carlo Pirazzi, Martin Adiels, Maria Antonella Burza, Rosellina Margherita Mancina, Malin Levin, Marcus Ståhlman, M. R. Taskinen, M. Orho-Melander, Jeanna Perman, A. Pujia, Linda Andersson, Cristina Maglio, T. Montalcini, Olov Wiklund, Jan Borén, Stefano Romeo
Journal of Hepatology - 2012 -
Kinetic Studies to Investigate Lipoprotein
Metabolism.
Jan Borén, Marja-Riitta Taskinen, Martin Adiels
Journal of internal medicine - 2012 -
Investigations of a compartmental model for leucine kinetics using non-linear mixed effects models with ordinary and stochastic differential
equations.
Martin Berglund, Mikael Sunnåker, Martin Adiels, Mats Jirstrand, Bernt Wennberg
Mathematical medicine and biology : a journal of the IMA - 2012 -
Evaluation of macrophage-specific promoters using lentiviral delivery in
mice.
Malin Levin, Ulf Lidberg, Pernilla Jirholt, Martin Adiels, Anna Wramstedt, K Gustafsson, D R Greaves, S Li, S Fazio, M F Linton, Sven-Olof Olofsson, Jan Borén, Inger Gjertsson
Gene therapy - 2012 -
PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese
individuals
Maria Antonella Burza, Carlo Pirazzi, Cristina Maglio, Kajsa Sjöholm, Rosellina Margherita Mancina, Per-Arne Svensson, Peter Jacobson, Martin Adiels, M. G. Baroni, Jan Borén, S. G. Corradini, T. Montalcini, Lars Sjöström, Lena M S Carlsson, Stefano Romeo
Digestive and Liver Disease - 2012 -
Interleukin 15 Mediates Joint Destruction in Staphylococcus Aureus
Arthritis
Louise Henningsson, Pernilla Jirholt, Yalda Rahpeymai Bogestål, Tove Eneljung, Martin Adiels, Catharina Lindholm, I. McInnes, S. Bulfone-Paus, Ulf H Lerner, Inger Gjertsson
Journal of Infectious Diseases - 2012 -
Paradoxical Lower Serum Triglyceride Levels and Higher Type 2 Diabetes Mellitus Susceptibility in Obese Individuals with the PNPLA3 148M
Variant
C. N. A. Palmer, Cristina Maglio, Carlo Pirazzi, Maria Antonella Burza, Martin Adiels, L. Burch, L. A. Donnelly, H. Colhoun, A. S. Doney, J. F. Dillon, E. R. Pearson, M. McCarthy, A. T. Hattersley, T. Frayling, A. D. Morris, Markku Peltonen, Per-Arne Svensson, Peter Jacobson, Jan Borén, Lars Sjöström, Lena M S Carlsson, Stefano Romeo
PLoS ONE - 2012 -
Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance
capacity.
Martin Adiels, Niina Matikainen, Jukka Westerbacka, Sanni Söderlund, Thomas Larsson, Sven-Olof Olofsson, Jan Borén, Marja-Riitta Taskinen
Atherosclerosis - 2012 -
Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2
diabetes.
Marcus Ståhlman, H T Pham, Martin Adiels, T W Mitchell, S J Blanksby, Björn Fagerberg, Kim Ekroos, Jan Borén
Diabetologia - 2012 -
Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young
men.
Kyriakoula Marinou, Martin Adiels, Leanne Hodson, Keith N Frayn, Fredrik Karpe, Barbara A Fielding
The British journal of nutrition - 2011 -
Dual metabolic defects are required to produce hypertriglyceridemia in obese
subjects.
Marja-Riitta Taskinen, Martin Adiels, Jukka Westerbacka, Sanni Söderlund, Juhani Kahri, Nina Lundbom, Jesper Lundbom, Antti Hakkarainen, Sven-Olof Olofsson, Marju Orho-Melander, Jan Borén
Arteriosclerosis, thrombosis, and vascular biology - 2011 -
Optimization of N-methyl-N-[tert-butyldimethylsilyl]trifluoroacetamide as a derivatization agent for determining isotopic enrichment of glycerol in very-low density
lipoproteins.
Martin Adiels, Thomas Larsson, Pauline Sutton, Marja-Riitta Taskinen, Jan Borén, Barbara A Fielding
Rapid communications in mass spectrometry : RCM - 2010 -
A brief review of lipoprotein
metabolism
Martin Adiels, Sven-Olof Olofsson, Marja-Riitta Taskinen, Jan Borén
Evidence-Based Management of Lipid Disorders - 2009 -
ApoCIII-Enriched LDL in Type 2 Diabetes Displays Altered Lipid Composition, Increased Susceptibility for Sphingomyelinase and Increased binding to
Biglycan.
A Hiukka, Marcus Ståhlman, Camilla Pettersson, Malin Levin, Martin Adiels, Susann Teneberg, ES Leinonen, Lillemor Mattsson Hultén, Olov Wiklund, M Oresic, Sven-Olof Olofsson, MR Taskinen, K Ekroos, Jan Borén
Diabetes - 2009 -
The Lipid Droplet: a Dynamic Organelle, not only Involved in the Storage and Turnover of
Lipids
Sven-Olof Olofsson, Pontus Boström, Jens O. Lagerstedt, Linda Andersson, Martin Adiels, Jeanna Perman, Mikael Rutberg, Lu Li, Jan Borén
Cellular Lipid Metabolism - 2009 -
BASELINE apoB-100 AND TRIGLYCERIDE KINETICS PREDICTS POSTPRANDIAL TRIGLYCERIDE AND apoB-48 ACCUMULATION IN CHYLOMICRON, VLDL1 AND VLDL2
FRACTIONS
Martin Adiels, Niina Matikainen, Jukka Westerbacka, S Soderlund, Jan Borén, Marja-Riitta Taskinen
XV International Symposium on Atherosclerosis - 2009 -
Rekrytering av medicinare till forskning kräver tidigt engagemang. Amanuensprogram visar att tidig forskningsstart ger bättre
resultat.
Jan Borén, Martin Adiels, Ylva Wickström, Sven-Olof Olofsson, Pontus Boström
Läkartidningen - 2009 -
Nutritional systems biology modeling: from molecular mechanisms to
physiology.
Albert A de Graaf, Andreas P Freidig, Baukje De Roos, Neema Jamshidi, Matthias Heinemann, Johan A C Rullmann, Kevin D Hall, Martin Adiels, Ben van Ommen
PLoS computational biology - 2009 -
A Matlab Toolbox for Nonlinear Mixed Effects Modeling – Illustrated with a Model for Lipoprotein
Kinetics
Mikael Sunnåker, Martin Berglund, Bernt Wennberg, Martin Adiels, Mats Jirstrand
9th International Conference on Systems Biology - 2008 -
Fatty liver, insulin resistance, and
dyslipidemia.
Martin Adiels, Marja-Riitta Taskinen, Jan Borén
Current diabetes reports - 2008 -
ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition and increased susceptibility for
sphingomyelinase
Anne Hiukka, Marcus Ståhlman, Camilla Pettersson, Malin Levin, Martin Adiels, Susann Teneberg, Olov Wiklund, Matej Oresic, Sven-Olof Olofsson, Marja-Riitta Taskinen, Kim Ekroos, Jan Borén
CHEMISTRY AND PHYSICS OF LIPIDS - 2008 -
Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic
syndrome.
Martin Adiels, Sven-Olof Olofsson, Marja-Riitta Taskinen, Jan Borén
Arteriosclerosis, thrombosis, and vascular biology - 2008 -
Visceral Adiposity, Liver Fat, and Atherogenic
Dyslipidemia
Marja-Riitta Taskinen, Martin Adiels, Jan Borén
Abdominal Obesity and the Endocannabinoid System: From Basic Aspects to Clinical Management of Related Cardiometabolic Risk - 2008 -
Acute suppression of VLDL(1) secretion rate by insulin is associated with hepatic fat content and insulin
resistance
Martin Adiels, J. Westerbacka, A. Soro-Paavonen, A. M. Hakkinen, S. Vehkavaara, M. J. Caslake, C. Packard, Sven-Olof Olofsson, H. Yki-Jarvinen, M. R. Taskinen, Jan Borén
Diabetologia - 2007 -
Liver Fat Influences both the Baseline Production- and the Acute Regulation of VLDL1 TG and
apoB
Martin Adiels, Jukka Westerbacka, A. Soro-Paavonen, A-M Haakinen, S. Vehkavaara, M. J. Caslake, C. Packard, Sven-Olof Olofsson, Hannele Yki-Järvinen, Marja-Riitta Taskinen, Jan Borén
ATHEROSCLEROSIS SUPPLEMENTS - 2007 -
Liver fat influences both the baseline production – and the acute regulation of VLDL1 triglycerides (TG) and
apoB
Martin Adiels, Marja-Riitta Taskinen, Jan Borén
13rdAnnual Scandinavian Atherosclerosis Conference - 2007 -
Diabetic
dyslipidaemia
Martin Adiels, Sven-Olof Olofsson, M. R. Taskinen, Jan Borén
Curr Opin Lipidol - 2006 -
Overproduction of large VLDL particles is driven by increased liver fat content in
man
Martin Adiels, M. R. Taskinen, C. Packard, M. J. Caslake, A. Soro-Paavonen, J. Westerbacka, S. Vehkavaara, A. Hakkinen, Sven-Olof Olofsson, H. Yki-Jarvinen, Jan Borén
Diabetologia - 2006 -
Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic
dyslipidemia
Martin Adiels, Jan Borén, M. J. Caslake, P. Stewart, Aina Soro, J. Westerbacka, Bernt Wennberg, Sven-Olof Olofsson, C. Packard, M. R. Taskinen
Arterioscler Thromb Vasc Biol - 2005 -
A new combined multicompartmental model for apolipoprotein B-100 and triglyceride metabolism in VLDL
subfractions
Martin Adiels, C. Packard, M. J. Caslake, P. Stewart, A. Soro, J. Westerbacka, Bernt Wennberg, Sven-Olof Olofsson, M. R. Taskinen, Jan Borén
J Lipid Res - 2005 -
Compartmental models of lipoprotein
kinetics
Martin Adiels
2004 -
How does mutant proprotein convertase neural apoptosis-regulated convertase 1 induce autosomal dominant
hypercholesterolemia?
Pernilla Jirholt, Martin Adiels, Jan Borén
Arterioscler Thromb Vasc Biol - 2004 -
A compartmental model for kinetics of Apolipoprotein B-100 and Triglycerides in VLDL_1 and VLDL_2 in normolipidemic
subjects
Martin Adiels
2002