Morten Grötli

Professor

Department of Chemistry & Molecular

Biology

Telephone

+46 31-786 90 17

+46 766-22 90 17

Mail

morten.grotli@gu.se

Fax

+46 31-772 34 99

Visiting address

Kemigården 4

412 96 Göteborg

Room number

8013

Postal address

Kemigården 4

412 96 Göteborg

About Morten Grötli

See: The Grøtli Lab

Publications

Tuning liver pyruvate kinase activity up or down with a new class of allosteric
modulators

Amalyn Nain-Perez, Oscar Nilsson, A. Lulla, Liliana Håversen, P. Brear, Sara Liljenberg, M. Hyvonen, Jan Borén, Morten Grötli
European Journal of Medicinal Chemistry - 2023
Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate
Kinase

Umberto Battisti, Chunxia Gao, Fady Akladios, W. Kim, H. Yang, C. Bayram, I. Bolat, M. Kiliclioglu, N. Yuksel, O. O. Tozlu, C. Zhang, J. Sebhaoui, S. Iqbal, S. Shoaie, A. Hacimuftuoglu, S. Yildirim, H. Turkez, M. Uhlen, Jan Borén, A. Mardinoglu, Morten Grötli
Nutrients - 2023
Serendipitous Identification of a Covalent Activator of Liver Pyruvate
Kinase

Umberto Battisti, Chunxia Gao, Oscar Nilsson, Fady Akladios, A. Lulla, A. Bogucka, Amalyn Nain-Perez, Liliana Håversen, W. Kim, Jan Borén, M. Hyvonen, M. Uhlen, A. Mardinoglu, Morten Grötli
Chembiochem - 2022
Development of Dicationic Bisguanidine-Arylfuran Derivatives as Potent Agents against Gram-Negative
Bacteria.

Catarina Bourgard, Diego Rodríguez-Hernández, Anastasia Rudenko, Carolin Rutgersson, Martin Palm, D. G. Joakim Larsson, Anne Farewell, Morten Grøtli, Per Sunnerhagen
Antibiotics - 2022
Design and development of photoswitchable DFG-Out RET kinase
inhibitors

Yongjin Xu, Chunxia Gao, Måns Andreasson, Liliana Håversen, Marta Carrasco, Cassandra L. Fleming, T. Lundback, J. Andreasson, Morten Grötli
European Journal of Medicinal Chemistry - 2022
Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate
kinase

Amalyn Nain-Perez, Anders Füchtbauer, Liliana Håversen, A. Lulla, Chunxia Gao, Josipa Matic, Letitia Monjas, Alexandra Rodriguez, P. Brear, W. Kim, M. Hyvonen, Jan Borén, A. Mardinoglu, M. Uhlen, Morten Grötli
European Journal of Medicinal Chemistry - 2022
Environmentally friendly catechol-based synthesis of
dibenzosultams

Sara Liljenberg, Amalyn Nain-Perez, Oscar Nilsson, Josipa Matic, Morten Grötli
New Journal of Chemistry - 2022
A genetic trap in yeast for inhibitors of SARS-CoV-2 Main
Protease.

Hanna Alalam, Sunniva Sigurdardóttir, Catarina Bourgard, Ievgeniia Tiukova, Ross D King, Morten Grøtli, Per Sunnerhagen
mSystems - 2021
Design and development of a photoswitchable DFG-out kinase
inhibitor

Yongjin Xu, Chunxia Gao, Liliana Håversen, T. Lundback, J. Andreasson, Morten Grötli
Chemical Communications - 2021
Interbase-FRET binding assay for
pre-microRNAs

Mattias Bood, A. W. del Nogal, J. R. Nilsson, F. Edfeldt, A. Dahlen, M. Lemurell, L. M. Wilhelmsson, Morten Grötli
Scientific Reports - 2021
Discovery of Functional Alternatively Spliced PKM Transcripts in Human
Cancers

X. Y. Li, W. Kim, M. Arif, Chunxia Gao, A. Hober, D. Kotol, L. Strandberg, B. Forsstrom, A. Sivertsson, P. Oksvold, H. Turkez, Morten Grötli, Y. Sato, H. Kume, S. Ogawa, Jan Borén, J. Nielsen, M. Uhlen, C. Zhang, A. Mardinoglu
Cancers - 2021
A small molecule targeting human MEK1/2 enhances ERK and p38 phosphorylation under oxidative stress or with
phenothiazines.

Michal Otreba, Johanna Johansson Sjölander, Morten Grøtli, Per Sunnerhagen
Life (Basel) - 2021
Getting DNA and RNA out of the dark with 2CNqA: a bright adenine analogue and interbase FRET
donor

A. W. del Nogal, Anders Füchtbauer, Mattias Bood, J. R. Nilsson, M. S. Wranne, S. Sarangamath, P. Pfeiffer, V. S. Rajan, A. H. El-Sagheer, A. Dahlen, T. Brown, Morten Grötli, L. M. Wilhelmsson
Nucleic Acids Research - 2020
Peroxiredoxin promotes longevity and H2O2-resistance in yeast through redox-modulation of protein kinase
A

Friederike Roger, C. Picazo, W. Reiter, M. Libiad, Chikako Asami, Sarah Hanzén, Chunxia Gao, G. Lagniel, Niek Welkenhuysen, J. Labarre, Thomas Nyström, Morten Grötli, M. Hartl, M. B. Toledano, Mikael Molin
eLife - 2020
A redox-sensitive thiol in Wis1 modulates the fission yeast MAPK response to H2O2 and is the target of a small
molecule.

Johanna J Sjölander, Agata Tarczykowska, Cecilia Picazo, Itziar Cossio, Itedale Namro Redwan, Chunxia Gao, Carlos Solano, Michel B Toledano, Morten Grøtli, Mikael Molin, Per Sunnerhagen
Molecular and Cellular Biology - 2020
Lighting Up DNA with the Environment-Sensitive Bright Adenine Analogue
qAN4

A. F. F?chtbauer, M. S. Wranne, S. Sarangamath, Mattias Bood, A. H. El-Sagheer, T. Brown, H. Grad?n, Morten Grötli, L. M. Wilhelmsson
Chempluschem - 2020
On-Command Regulation of Kinase Activity using Photonic
Stimuli

Cassandra L. Fleming, Morten Grötli, J. Andreasson
ChemPhotoChem - 2019
A Fluorescent Kinase Inhibitor that Exhibits Diagnostic Changes in Emission upon
Binding

Cassandra L. Fleming, Patrick A Sandoz, Tord Inghardt, Björn Önfelt, Morten Grøtli, Joakim Andréasson
Angewandte Chemie - International Edition - 2019
Fluorescent nucleobase analogues for base-base FRET in nucleic acids: Synthesis, photophysics and
applications

Mattias Bood, Sangamesh Sarangamath, Moa S. Wranne, Morten Grøtli, Marcus Wilhelmsson
Beilstein Journal of Organic Chemistry - 2018
Shining New Light on the Spiropyran Photoswitch: A Photocage Decides between cis-trans or Spiro-Merocyanine
Isomerization

Cassandra L. Fleming, S. M. Li, Morten Grötli, J. Andreasson
Journal of the American Chemical Society - 2018
Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine
analogue

Christopher P. Lawson, A. F. Fuchtbauer, M. S. Wranne, T. Giraud, T. Floyd, B. Dumat, N. K. Andersen, A. H. El-Sagheer, T. Brown, H. Graden, L. M. Wilhelmsson, Morten Grötli
Scientific Reports - 2018
Pulse-shaped two-photon excitation of a fluorescent base analogue approaches single-molecule
sensitivity

R. S. Fisher, D. Nobis, A. F. Füchtbauer, Mattias Bood, Morten Grøtli, L. M. Wilhelmsson, A. C. Jones, S. W. Magennis
Physical Chemistry Chemical Physics - 2018
Synthesis and Photophysical Characterization of
Azoheteroarenes

Yongjin Xu, Chunxia Gao, J. Andreasson, Morten Grötli
Organic Letters - 2018
Drug Repositioning for Effective Prostate Cancer
Treatment

B. Turanli, Morten Grötli, Jan Borén, J. Nielsen, M. Uhlen, K. Y. Arga, A. Mardinoglu
Frontiers in Physiology - 2018
Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base
analogue

Mattias Bood, A. F. Fuchtbauer, M. S. Wranne, J. J. Ro, S. Sarangamath, A. H. El-Sagheer, D. L. M. Rupert, R. S. Fisher, S. W. Magennis, A. C. Jones, F. Hook, T. Brown, B. H. Kim, A. Dahlen, L. M. Wilhelmsson, Morten Grötli
Chemical Science - 2018
Plasmodium dihydrofolate reductase is a second enzyme target for the antimalarial action of
triclosan

E. Bilsland, L. van Vliet, K. Williams, J. Feltham, Marta Carrasco, W. L. Fotoran, E. F. G. Cubillos, G. Wunderlich, Morten Grötli, F. Hollfelder, V. Jackson, R. D. King, S. G. Oliver
Scientific Reports - 2018
Network analyses identify liver-specific targets for treating liver
diseases.

Sunjae Lee, Cheng Zhang, Zhengtao Liu, Martina Klevstig, Bani Mukhopadhyay, Mattias Bergentall, Resat Cinar, Marcus Ståhlman, Natasha Sikanic, Joshua K Park, Sumit Deshmukh, Azadeh M Harzandi, Tim Kuijpers, Morten Grøtli, Simon J Elsässer, Brian D Piening, Michael Snyder, Ulf Smith, Jens Nielsen, Fredrik Bäckhed, George Kunos, Mathias Uhlen, Jan Borén, Adil Mardinoglu
Molecular systems biology - 2017
Improving the economics of NASH/NAFLD treatment through the use of systems
biology

J. Bosley, C. Boren, S. Lee, Morten Grötli, J. Nielsen, M. Uhlen, Jan Borén, A. Mardinoglu
Drug Discovery Today - 2017
Toward Complete Sequence Flexibility of Nucleic Acid Base Analogue
FRET

M. S. Wranne, A. F. Fuchtbauer, B. Dumat, Mattias Bood, A. H. El-Sagheer, T. Brown, H. Graden, Morten Grötli, L. M. Wilhelmsson
Journal of the American Chemical Society - 2017
On the use of diarylmaleimide derivatives in biological contexts: An investigation of the photochromic properties in aqueous
solution

C. Fleming, P. Remon, S. Li, N. A. Simeth, B. Konig, Morten Grötli, J. Andreasson
Dyes and Pigments - 2017
Arsenic Directly Binds to and Activates the Yeast AP-1-Like Transcription Factor
Yap8.

Nallani Vijay Kumar, Jianbo Yang, Jitesh K Pillai, Swati Rawat, Carlos Solano, Abhay Kumar, Morten Grøtli, Timothy L Stemmler, Barry P Rosen, Markus J. Tamás
Molecular and cellular biology - 2016
Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic
β-hairpins

Emma Danelius, Mariell Pettersson, Matilda Bred, Jaeki Min, M. Brett Waddell, R. Kiplin Guy, Morten Grøtli, Mate Erdelyi
Organic and Biomolecular Chemistry - 2016
Structural Insights into the Polyphyletic Origins of Glycyl tRNA
Synthetases

M. I. Valencia-Sanchez, A. Rodriguez-Hernandez, Rubén Ferreira, H. A. Santamaria-Suarez, M. Arciniega, A. C. Dock-Bregeon, D. Moras, B. Beinsteiner, H. Mertens, D. Svergun, L. G. Brieba, Morten Grøtli, A. Torres-Larios
Journal of Biological Chemistry - 2016
7-(Benzofuran-2-yl)-7-deazadeoxyguanosine as a fluorescence turn-ON probe for single-strand DNA binding
protein

M. Tokugawa, Y. Masaki, J. C. Canggadibrata, K. Kaneko, T. Shiozawa, T. Kanamori, Morten Grøtli, Marcus Wilhelmsson, M. Sekine, K. Seio
Chemical Communications - 2016
An acido- and photochromic molecular device that mimics triode
action

P. Remón, Shiming Li, Morten Grötli, U. Pischel, Joakim Andréasson
Chemical Communications - 2016
Defects in the calcium-binding region drastically affect the cadherin-like domains of RET tyrosine
kinase

Chunxia Gao, Morten Grøtli, Leif A Eriksson
Physical Chemistry Chemical Physics - 2016
Chroman-4-one and chromone based somatostatin beta-turn
mimetics

Maria Fridén-Saxin, Tina Seifert, Marcus Malo, Krystle da Silva Andersson, Nils Pemberton, Christine Dyrager, Annika Friberg, Kristian Dahlén, Erik A A Wallén, Morten Grøtli, Kristina Luthman
European Journal of Medicinal Chemistry - 2016
Second-Generation Fluorescent Quadracyclic Adenine Analogues: Environment-Responsive Probes with Enhanced
Brightness

B. Dumat, Mattias Bood, Moa Sandberg Wranne, Christopher P. Lawson, Anders Foller Larsen, S. Preus, J. Streling, H. Gradén, E. Wellner, Morten Grøtli, Marcus Wilhelmsson
Chemistry - A European Journal - 2015
A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish
Embryos

David Bliman, Jesper Nilsson, Petronella Kettunen, Joakim Andréasson, Morten Grøtli
Scientific Reports - 2015
8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53
Interaction

Mariell Pettersson, David Bliman, Jimmy Jacobsson, Jesper Nilsson, J. Min, L. Iconaru, R. K. Guy, R. W. Kriwacki, Joakim Andréasson, Morten Grøtli
PLoS ONE - 2015
Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase
Inhibitors.

Rubén Ferreira, Jesper Nilsson, Carlos Solano, Joakim Andréasson, Morten Grøtli
Scientific reports - 2015
Development of bright fluorescent quadracyclic adenine analogues: TDDFT-calculation supported rational
design

Anders Foller Larsen, Blaise Dumat, Moa Sandberg Wranne, Christopher P. Lawson, S. Preus, Mattias Bood, Henrik Gradén, Marcus Wilhelmsson, Morten Grøtli
Scientific Reports - 2015
Design, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53
Interaction

Mariell Pettersson, Maria Quant, J. Min, L. Iconaru, R. W. Kriwacki, M. B. Waddell, R. K. Guy, Kristina Luthman, Morten Grøtli
PLoS ONE - 2015
The unique characteristics of HOG pathway MAPKs in the extremely halotolerant Hortaea
werneckii

A. Kejzar, M. Cibic, Morten Grøtli, A. Plemenitas, M. Lenassi
Fems Microbiology Letters - 2015
Characterization of interactions and pharmacophore development for DFG-out inhibitors to RET tyrosine
kinase

Chunxia Gao, Morten Grøtli, Leif A Eriksson
Journal of Molecular Modeling - 2015
HwHog1 kinase activity is crucial for survival of Hortaea werneckii in extremely hyperosmolar
environments.

Anja Kejžar, Morten Grøtli, Markus J. Tamás, Ana Plemenitaš, Metka Lenassi
Fungal genetics and biology : FG & B - 2015
A Single-Cell Study of a Highly Effective Hog1 Inhibitor for in Situ Yeast Cell
Manipulation

Charlotte Hamngren Blomqvist, Peter Dinér, Morten Grøtli, Mattias Goksör, Caroline B. Adiels
Micromachines - 2014
Application of a peptide-based assay to characterize inhibitors targeting protein kinases from
yeast

Jenny Veide Vilg, Sita Dahal, Thomas Ljungdahl, Morten Grøtli, Markus J. Tamás
Current Genetics - 2014
Chromo-pharmacophores: Photochromic diarylmaleimide inhibitors for
sirtuins

C. Falenczyk, M. Schiedel, B. Karaman, T. Rumpf, N. Kuzmanovic, Morten Grötli, W. Sippl, M. Jung, B. König
Chemical Science - 2014
Synthesis and photophysical characterisation of new fluorescent triazole adenine
analogues

Christopher P. Lawson, Anke Dierckx, Francois-Alexandre Miannay, E. Wellner, Marcus Wilhelmsson, Morten Grøtli
Organic & Biomolecular Chemistry - 2014
Photoswitch kinase
inhibitors

Raphael Ferreira, Jesper Nilsson, C. Solano, Joakim Andréasson, Morten Grötli
Purinergic Signalling - 2014
8-Bromination of 2,6,9-trisubstituted purines with pyridinium
tribromide

David Bliman, Mariell Pettersson, Mattias Bood, Morten Grøtli
Tetrahedron Letters - 2014
Inhibition of MAPK Hog1 Results in Increased Hsp104 Aggregate Formation Probably through Elevated Arsenite Influx into the Cells, an Approach with Numerous Potential
Applications

Doryaneh Ahmadpour, Amin Abbaszadehbanaeiyan, Morten Grøtli, Martin Adiels, Mattias Goksör, Caroline B. Adiels
American Journal of Molecular Biology - 2014
Selective inhibition of RET mediated cell proliferation in vitro by the kinase inhibitor
SPP86

John Patrick Alao, Sona Michlíková, Peter Dinér, Morten Grøtli, Per Sunnerhagen
BMC Cancer - 2014
Towards the development of chromone-based MEK1/2
modulators

Itedale Namro Redwan, Christine Dyrager, Carlos Solano, Guillermo Fernández de Trocóniz, L. Voisin, David Bliman, S. Meloche, Morten Grøtli
European Journal of Medicinal Chemistry - 2014
Synthesis and photophysical characterization of 1-and 4-(purinyl)
triazoles

Itedale Namro Redwan, David Bliman, Munefumi Tokugawa, Christopher P. Lawson, Morten Grøtli
Tetrahedron - 2013
Effect of MAPK Inhibitor on the Arsenite uptake by Aquaglyceroporin in Single Yeast
Cells.

Doryaneh Ahmadpour, Amin Abbaszadehbanaeiyan, Morten Grøtli, Mattias Goksör, Caroline B. Adiels
Optical Molecular Probes, Imaging and Drug Delivery - 2013
Investigation, optimization and synthesis of sulfamoyloxy-linked aminoacyl-AMP
analogues

Itedale Namro Redwan, Thomas Ljungdahl, Morten Grøtli
Tetrahedron - 2012
Design and evaluation of a microfluidic system for inhibition studies of yeast cell
signaling

Charlotte Hamngren Blomqvist, Peter Dinér, Morten Grøtli, Mattias Goksör, Caroline B. Adiels
Proceedings of SPIE - The International Society for Optical Engineering. Optical Trapping and Optical Micromanipulation IX, San Diego, 12-16 August 2012 - 2012
Determination of primary sequence specificity of Arabidopsis MAPKs MPK3 and MPK6 leads to identification of new
substrates.

Carolin Sörensson, Marit Lenman, Jenny Veide Vilg, Simone Schopper, Thomas Ljungdahl, Morten Grøtli, Markus J. Tamás, Scott C Peck, Erik Andreasson
The Biochemical journal - 2012
Proline-mediated formation of novel chroman-4-one
tetrahydropyrimidines

Maria Fridén-Saxin, Tina Seifert, L. K. Hansen, Morten Grøtli, Mate Erdelyi, Kristina Luthman
Tetrahedron - 2012
Preparation of 3-Substituted-1-Isopropyl-1H-pyrazolo 3,4-d pyrimidin-4-amines as RET Kinase
Inhibitors

Peter Dinér, John Patrick Alao, J. Söderlund, Per Sunnerhagen, Morten Grøtli
Journal of Medicinal Chemistry - 2012
Validation of regulated protein phosphorylation events in yeast by quantitative mass spectrometry analysis of purified
proteins

W. Reiter, D. Anrather, I. Dohnal, P. Pichler, J. Veis, Morten Grøtli, F. Posas, G. Ammerer
Proteomics - 2012
Method for Activation and Recycling of Trityl
Resins

Itedale Namro Redwan, Morten Grøtli
Journal of Organic Chemistry - 2012
Solid-Phase Synthesis of 5 '-O- N-(Acyl)sulfamoyl adenosine
Derivatives

Itedale Namro Redwan, Hanna Jacobson Ingemyr, Thomas Ljungdahl, Christopher P. Lawson, Morten Grøtli
European Journal of Organic Chemistry - 2012
NMR-Based Substrate Analog Docking to Escherichia coli Peptidyl-tRNA
Hydrolase

L Giorgi, P Plateau, Gavin O'Mahony, C Aubard, M Fromant, A Thureau, Morten Grötli, S Blanquet, F Bontems
JOURNAL OF MOLECULAR BIOLOGY - 2011
Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in
DNA

Anke Dierckx, Peter Dinér, A. H. El-Sagheer, Joshi Dhruval Kumar, T. Brown, Morten Grøtli, Marcus Wilhelmsson
Nucleic Acids Research - 2011
Design, synthesis, and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signaling in
yeast.

Peter Dinér, Jenny Veide Vilg, Jimmy Kjellén, Iwona Migdal, Terese Andersson, Marinella Gebbia, Guri Giaever, Corey Nislow, Stefan Hohmann, Robert Wysocki, Markus J. Tamás, Morten Grøtli
PloS one - 2011
Design, Synthesis and Characterization of a Highly Effective Inhibitor for Analog-Sensitive (as)
Kinases

Michael Klein, M Morillas, A Vendrell, Lars Brive, M Gebbia, IM Wallace, G Giaever, C Nislow, F Posas, Morten Grøtli
PLOS ONE - 2011
Design, synthesis, and biological evaluation of chromone-based p38 MAP kinase
inhibitors

Christine Dyrager, Linda N Möllers, Linda K Kjäll, John Patrick Alao, Peter Dinér, Fredrik Wallner, Per Sunnerhagen, Morten Grøtli
Journal of Medicinal Chemistry - 2011
Inhibitors and promoters of tubulin polymerization: Synthesis and biological evaluation of chalcones and related dienones as potential anticancer
agents.

Christine Dyrager, Malin Wickström, Maria Fridén-Saxin, Annika Friberg, Kristian Dahlén, Erik A A Wallén, Joachim Gullbo, Morten Grøtli, Kristina Luthman
Bioorganic & medicinal chemistry - 2011
Structural Influence on Radical Formation and Sensitizing Capacity of Alkylic Limonene Hydroperoxide Analogues in Allergic Contact
Dermatitis.

Staffan G H Johansson, Katarina Emilsson, Morten Grøtli, Anna Börje
Chemical research in toxicology - 2010
Design, synthesis and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signalling in
yeast

Peter Dinér, Jenny Veide Vilg, Jimmy Kjellén, Iwona Migdal, Therese Andersson, Stefan Hohmann, Robert Wysocki, Markus J. Tamás, Morten Grøtli
35th FEBS Congress, Gothenburg, Sweden - 2010
Positional Scanning Peptide Libraries for Kinase Substrate Specificity Determinations: Straightforward and Reproducible Synthesis Using Pentafluorophenyl
Esters.

Thomas Ljungdahl, Jenny Veide Vilg, Fredrik Wallner, Markus J. Tamás, Morten Grøtli
Journal of combinatorial chemistry - 2010
Design, synthesis and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signalling in
yeast

Peter Dinér, Jenny Veide Vilg, Jimmy Kjellén, Iwona Migdal, Therese Andersson, Stefan Hohmann, Robert Wysocki, Markus J. Tamás, Morten Grøtli
Yeast Genetics and Molecular Biology Meeting, Vancouver, Canada - 2010
KHMDS enhanced SmI(2)-mediated reformatsky type
alpha-cyanation.

Tobias Ankner, Maria Fridén-Saxin, Nils Pemberton, Tina Seifert, Morten Grøtli, Kristina Luthman, Göran Hilmersson
Organic letters - 2010
Synthesis and Photophysical Characterisation of Fluorescent 8-(1H-1,2,3-Triazol-4-yl)adenosine
Derivatives

Christine Dyrager, Karl Börjesson, P. Diner, A. Elf, Bo Albinsson, Marcus Wilhelmsson, Morten Grøtli
European Journal of Organic Chemistry - 2009
2,6,8-Trisubstituted 3-hydroxychromone derivatives as fluorophores for live-cell
imaging.

Christine Dyrager, Annika Friberg, Kristian Dahlén, Maria Fridén-Saxin, Karl Börjesson, Marcus Wilhelmsson, Maria Smedh, Morten Grøtli, Kristina Luthman
Chemistry (Weinheim an der Bergstrasse, Germany) - 2009
Highly selective, cell-permeable and fast-acting wild-type Hog1 inhibitors as tools for studying cellular function of
kinases

Peter Dinér, Jenny Veide Vilg, Jimmy Kjellén, Terese Andersson, Stefan Hohmann, Markus J. Tamás, Morten Grøtli
Functional Genomics Symposium: Chemical Biology – Molecules to Probe Life, Gothenburg, Sweden - 2009
Synthesis and use of positional scanning peptide libraries for determination of kinase substrate consensus
sequences

Jenny Veide Vilg, Thomas Ljungdahl, Markus J. Tamás, Morten Grøtli
Functional Genomics Symposium: Chemical Biology – Molecules to Probe Life, Gothenburg, Sweden - 2009
Synthesis of chiral 1,4-disubstituted-1,2,3-triazole derivatives from amino
acids.

Michael Klein, Karin Krainz, Itedale Namro Redwan, Peter Dinér, Morten Grøtli
Molecules (Basel, Switzerland) - 2009
Short cut to 1,2,3-triazole-based p38 MAP kinase inhibitors via [3+2]-cycloaddition
chemistry

Peter Dinér, Terese Andersson, Jimmy Kjellén, Karin Elbing, Stefan Hohmann, Morten Grøtli
New J. Chem., - 2009
Solid-phase peptide synthesis in water using microwave-assisted
heating.

Athanassios S Galanis, Fernando Albericio, Morten Grøtli
Organic letters - 2009
Synthesis of 2-alkyl-substituted chromone derivatives using microwave
irradiation.

Maria Fridén-Saxin, Nils Pemberton, Krystle da Silva Andersson, Christine Dyrager, Annika Friberg, Morten Grøtli, Kristina Luthman
The Journal of organic chemistry - 2009
Enhanced microwave-assisted method for on-bead disulfide bond formation: synthesis of alpha-conotoxin
MII.

Athanassios S Galanis, Fernando Albericio, Morten Grøtli
Biopolymers - 2009
Synthesis of 3-(1,2,3-triazol-1-yl)- and 3-(1,2,3-triazol-4-yl)-substituted pyrazolo[3,4-d]pyrimidin-4-amines via click chemistry: potential inhibitors of the Plasmodium falciparum PfPK7 protein
kinase.

Michael Klein, Peter Dinér, Dominique Dorin-Semblat, Christian Doerig, Morten Grøtli
Organic & biomolecular chemistry - 2009
Specificity of MAP kinase substrates – determination of consensus sequences using positional scanning peptide
libraries

Jenny Veide Vilg, Thomas Ljungdahl, Morten Grøtli, Markus J. Tamás
Yeast Genetics and Molecular Biology Meeting, Toronto, Canada - 2008
Synthesis of
2-([1,2,3]Triazol-1-yl)-2-deoxyadenosines

Gavin O'Mahony, Sara Svensson, Andreas Sundgren, Morten Grøtli
ChemInform - 2008
Carbon- and Oxygen-Centered Radicals Are Equally Important Haptens of Allylic Hydroperoxides in Allergic Contact
Dermatitis

Staffan Johansson, Elena Gimenez-Arnau, Morten Grøtli, Ann-Therese Karlberg, Anna Börje
Chem. Res. Toxicol. - 2008
Synthesis and photophysical properties of novel cyclonucleosides—substituent effects on fluorescence
emission

Gavin O'Mahony, Eleonor Ehrman, Morten Grøtli
Tetrahedron - 2008
Synthesis of functionalized, unsymmetrical 1,3,4,6-tetrasubstituted
2,5-diketopiperazines.

Marcus Tullberg, Morten Grøtli, Kristina Luthman
The Journal of organic chemistry - 2007
A practical synthesis of
2′-aminoacylamino-2′-deoxyadenosines

Gavin O'Mahony, Andreas Sundgren, Morten Grøtli
Tetrahedron - 2007
Microwave assisted synthesis of
spiro-2,5-diketopiperazines

Fariba Jam, Marcus Tullberg, Kristina Luthman, Morten Grøtli
Tetrahedron - 2007
Synthesis of 3-aminomethyl-2-aryl-
8-bromo-6-chlorochromones.

Erik A A Wallén, Kristian Dahlén, Morten Grøtli, Kristina Luthman
Organic letters - 2007
Synthesis of 2,3,6,8-tetrasubstituted chromone
scaffolds.

Kristian Dahlén, Erik A A Wallén, Morten Grøtli, Kristina Luthman
The Journal of organic chemistry - 2006
Microwave-assisted synthesis of the Schollkopf chiral auxiliaries: (3S)- and
(3R)-3,6-dihydro-2,5-diethoxy-3-isopropyl-pyrazine

Anna-Carin Carlsson, Fariba Jam, Marcus Tullberg, Åke Pilotti, Panos Ioannidis, Kristina Luthman, Morten Grøtli
Tetrahedron Letters - 2006
Microwave-assisted solid-phase synthesis of 2,5-diketopiperazines: solvent and resin
dependence.

Marcus Tullberg, Kristina Luthman, Morten Grøtli
Journal of combinatorial chemistry - 2006
A scaffold approach to 3,6,8-trisubstituted
flavones

Kristian Dahlén, Morten Grøtli, Kristina Luthman
Synlett - 2006
Role of the subunit composition of central nicotinic acetylcholine receptors for the stimulatory and dopamine-enhancing effects of
ethanol.

Elisabeth Jerlhag, Morten Grøtli, Kristina Luthman, Lennart Svensson, Jörgen Engel
Alcohol and Alcoholism - 2006
Discovering new classes of Brugia malayi asparaginyl-tRNA synthetase inhibitors and relating specificity to conformational
change.

Sai Chetan K Sukuru, Thibaut Crepin, Youli Milev, Liesl C Marsh, Jonathan B Hill, Regan J Anderson, Jonathan C Morris, Anjali Rohatgi, Gavin O'Mahony, Morten Grøtli, Franck Danel, Malcolm G P Page, Michael Härtlein, Stephen Cusack, Michael A Kron, Leslie A Kuhn
Journal of computer-aided molecular design - 2006
Efficient synthesis of 2,5-diketopiperazines using microwave assisted
heating

Marcus Tullberg, Morten Grøtli, Kristina Luthman
Tetrahedron - 2006
Design and synthesis of novel chromone based
peptidomimetics

K Dahlén, Morten Grøtli, Kristina Luthman
Biopolymers - 2005
Synthesis of adenosine-based fluorosides containing a novel heterocyclic ring
system

G O'Mahony, Eleonor Ehrman, Morten Grøtli
Tetrahedron Letters - 2005
The biotin repressor: Modulation of allostery by corepressor
analogs

P. H. Brown, J. E. Cronan, Morten Grøtli, D. Beckett
Journal of Molecular Biology - 2004