Cecilia Engdahl
Researcher
Department of Rheumatology a InflammationAbout Cecilia Engdahl
Cecilia Engdahl defended her dissertation in 2013 on the thesis "Arthritis and immune-mediated bone loss -role of estrogen signaling" here at Sahlgrenska Academy, University of Gothenburg. Followed by a Swedish Research Council-funded Post Doc in Germany, Erlangen University Clinic, FAU. She became an associate professor in 2019 and also received a Swedish Research council starting grant the same year.
Cecilia works at the Department of Rheumatology and Inflammation Research and in the research collaboration Center for Bone and Arthritis Research, CBAR.
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Transplantation of gut microbiota from old mice into young healthy mice reduces lean mass but not bone
mass
Lina Lawenius, C. Cowardin, Louise Grahnemo, Julia Scheffler, Karin Horkeby, Cecilia Engdahl, Jianyao Wu, Liesbeth Vandenput, A. Koskela, J. Tukkanen, E. Coward, K. Hveem, A. Langhammer, Sanna Abrahamsson, J. I. Gordon, Klara Sjögren, Claes Ohlsson
Gut Microbes - 2023 -
Bazedoxifene does not share estrogens effects on IgG
sialylation
Priti Gupta, Karin Horkeby, Hans Carlsten, Petra Henning, Cecilia Engdahl
Plos One - 2023 -
Membrane estrogen receptor alpha signaling modulates the sensitivity to estradiol treatment in a dose- and tissue- dependent
manner
Yiwen Jiang, Karin L Horkeby, Petra Henning, Jianyao Wu, Lina Lawenius, Cecilia Engdahl, Priti Gupta, Sofia Moverare-Skrtic, Karin H. Nilsson, E. Levin, Claes Ohlsson, Marie K Lagerquist
Scientific Reports - 2023 -
A COX-2 Inhibitor Does Not Interfere With the Bone-Protective Effects of Loading in Male Mice With
Arthritis
S. Desai, Jianyao Wu, Karin L Horkeby, M. Norgard, Claes Ohlsson, S. H. Windahl, Cecilia Engdahl
Jbmr Plus - 2023 -
The impact of TLR2 and aging on the humoral immune response to Staphylococcus aureus bacteremia in
mice.
Priti Gupta, Zhicheng Hu, Pradeep Kumar Kopparapu, Megshree Deshmukh, Tibor Saghy, Majd Mohammad, Tao Jin, Cecilia Engdahl
Scientific reports - 2023 -
The impact of aging and TLR2 deficiency on the clinical outcomes of Staphylococcus aureus
bacteremia.
Zhicheng Hu, Pradeep Kumar Kopparapu, Megshree Deshmukh, Anders Jarneborn, Priti Gupta, Abukar Ali, Ying Fei, Cecilia Engdahl, Rille Pullerits, Majd Mohammad, Tao Jin
The Journal of infectious diseases - 2023 -
A tissue-specific role of membrane-initiated ERα signaling for the effects of
SERMs
Karin L. Gustafsson, Sofia Movérare-Skrtic, Helen H. Farman, Cecilia Engdahl, Petra Henning, Karin H. Nilsson, Julia M. Scheffler, Edina Sehic, Ulrika Islander, E. Levin, Claes Ohlsson, Marie K Lagerquist
Journal of Endocrinology - 2022 -
ER alpha Signaling in a Subset of CXCL12-Abundant Reticular Cells Regulates Trabecular Bone in
Mice
Julia M. Scheffler, Karin L. Gustafsson, Aidan Barrett, Carmen Corciulo, Christina Drevinge, Alicia M. del Carpio Pons, Piotr Humeniuk, Cecilia Engdahl, J. A. Gustafsson, Claes Ohlsson, Hans Carlsten, Marie K Lagerquist, Ulrika Islander
JBMR Plus - 2022 -
Reduction of Mature B Cells and Immunoglobulins Results in Increased Trabecular
Bone
Marie K Lagerquist, P. Gupta, E. Sehic, Karin L Horkeby, Julia M. Scheffler, Jauqueline Nordqvist, Lina Lawenius, Ulrika Islander, Carmen Corciulo, Petra Henning, Hans Carlsten, Cecilia Engdahl
Jbmr Plus - 2022 -
A tissue-selective estrogen complex as treatment of osteoporosis in experimental
lupus
Jauqueline Nordqvist, Cecilia Engdahl, Julia M. Scheffler, Priti Gupta, Karin L. Gustafsson, Marie K Lagerquist, Hans Carlsten, Ulrika Islander
Lupus - 2022 -
Dietary Derived Propionate Regulates Pathogenic Fibroblast Function and Ameliorates Experimental Arthritis and Inflammatory Tissue
Priming
J. Friscic, K. Durholz, X. Chen, Cecilia Engdahl, L. Moller, G. Schett, M. M. Zaiss, M. H. Hoffmann
Nutrients - 2021 -
Immunoglobulin G complexes without sialic acids enhance osteoclastogenesis but do not affect arthritis-mediated bone
loss.
Edina Sehic, Anna Westerlund, Marie K Lagerquist, Ulf H Lerner, Hans Carlsten, Petra Henning, Cecilia Engdahl
Scandinavian journal of immunology - 2021 -
Arginine site 264 in murine estrogen receptor alpha is dispensable for the regulation of the
skeleton.
Karin L. Gustafsson, Helen H. Farman, Karin H. Nilsson, Petra Henning, Sofia Movérare-Skrtic, Vikte Lionikaite, Lina Lawenius, Cecilia Engdahl, Claes Ohlsson, Marie K Lagerquist
American journal of physiology. Endocrinology and metabolism - 2021 -
Interleukin 17A: a Janus-faced regulator of
osteoporosis
Julia M. Scheffler, Louise Grahnemo, Cecilia Engdahl, Christina Drevinge, Karin L. Gustafsson, Carmen Corciulo, Lina Lawenius, Y. Iwakura, Klara Sjögren, Marie Lagerquist, Hans Carlsten, Claes Ohlsson, Ulrika Islander
Scientific Reports - 2020 -
Tofacitinib treatment aggravates Staphylococcus aureus septic arthritis, but attenuates sepsis and enterotoxin induced shock in
mice
Anders Jarneborn, Majd Mohammad, Cecilia Engdahl, Zhicheng Hu, Manli Na, Abukar Ali, Tao Jin
Scientific Reports - 2020 -
Changes in mechanical loading affect arthritis-induced bone loss in
mice.
Anna-Maria Liphardt, Sara H Windahl, Edina Sehic, Nicole Hannemann, Karin L. Gustafsson, Aline Bozec, Georg Schett, Cecilia Engdahl
Bone - 2020 -
The YIN and YANG of lipoproteins in developing and preventing infectious arthritis by Staphylococcus
aureus.
Majd Mohammad, Minh-Thu Nguyen, Cecilia Engdahl, Manli Na, Anders Jarneborn, Zhicheng Hu, Anna Karlsson, Rille Pullerits, Abukar Ali, Friedrich Götz, Tao Jin
PLoS pathogens - 2019 -
Roles of activating functions 1 and 2 of estrogen receptor α in
lymphopoiesis.
Annica Andersson, Sofia Movérare-Skrtic, Angelina I Bernardi, Helen H. Farman, Pierre Chambon, Cecilia Engdahl, Marie Lagerquist, Sara H Windahl, Hans Carlsten, Claes Ohlsson, Ulrika Islander
The Journal of endocrinology - 2018 -
Estrogen induces St6gal1 expression and increases IgG sialylation in mice and patients with rheumatoid arthritis: A potential explanation for the increased risk of rheumatoid arthritis in postmenopausal
women
Cecilia Engdahl, A. Bondt, U. Harre, J. Raufer, R. Pfeifle, Alessandro Camponeschi, M. Wuhrer, M. Seeling, Inga-Lill Mårtensson, F. Nimmerjahn, G. Krönke, H. U. Scherer, Helena Forsblad d'Elia, G. Schett
Arthritis Research and Therapy - 2018 -
SERMs have substance-specific effects on bone, and these effects are mediated via ER alpha AF-1 in female
mice
Anna E Börjesson, Helen H. Farman, Sofia Movérare-Skrtic, Cecilia Engdahl, M. C. Antal, A. Koskela, J. Tuukkanen, Hans Carlsten, A. Krust, P. Chambon, Klara Sjögren, Marie K Lagerquist, Sara H Windahl, Claes Ohlsson
American Journal of Physiology-Endocrinology and Metabolism - 2016 -
IL-17-producing γδT cells are regulated by estrogen during development of experimental
arthritis.
Annica Andersson, Louise Grahnemo, Cecilia Engdahl, Alexandra Stubelius, Marie K Lagerquist, Hans Carlsten, Ulrika Islander
Clinical immunology (Orlando, Fla.) - 2015 -
Estrogen regulates T helper 17 phenotype and localization in experimental autoimmune
arthritis
Annica Andersson, Alexandra Stubelius, Merja Nurkkala Karlsson, Cecilia Engdahl, Malin Erlandsson, Louise Grahnemo, Marie K Lagerquist, Ulrika Islander
Arthritis Research & Therapy - 2015 -
Possible role of lymphocytes in glucocorticoid-induced increase in trabecular bone mineral
density.
Louise Grahnemo, Caroline Jochems, Annica Andersson, Cecilia Engdahl, Claes Ohlsson, Ulrika Islander, Hans Carlsten
The Journal of endocrinology - 2015 -
Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility
fractures.
Sofia Movérare-Skrtic, Petra Henning, Xianwen Liu, Kenichi Nagano, Hiroaki Saito, Anna E Börjesson, Klara Sjögren, Sara H Windahl, Helen H. Farman, Bert Kindlund, Cecilia Engdahl, Antti Koskela, Fu-Ping Zhang, Emma E Eriksson, Farasat Zaman, Ann Hammarstedt, Hanna Isaksson, Marta Bally, Ali Kassem, Catharina Lindholm, Olof Sandberg, Per Aspenberg, Lars Sävendahl, Jian Q Feng, Jan Tuckermann, Juha Tuukkanen, Matti Poutanen, Roland Baron, Ulf H Lerner, Francesca Gori, Claes Ohlsson
Nature Medicine - 2014 -
The effect of estrogen on bone requires ER alpha in nonhematopoietic cells but is enhanced by ER alpha in hematopoietic
cells
Petra Henning, Claes Ohlsson, Cecilia Engdahl, Helen H. Farman, Sara H Windahl, Hans Carlsten, Marie K Lagerquist
American Journal of Physiology-Endocrinology and Metabolism - 2014 -
The role of total and cartilage-specific estrogen receptor alpha expression for the ameliorating effect of estrogen treatment on
arthritis.
Cecilia Engdahl, Anna E Börjesson, Huamei Forsman, Annica Andersson, Alexandra Stubelius, Andree Krust, Pierre Chambon, Ulrika Islander, Claes Ohlsson, Hans Carlsten, Marie K Lagerquist
Arthritis research & therapy - 2014 -
Probiotics protect mice from ovariectomy-induced cortical bone
loss.
Claes Ohlsson, Cecilia Engdahl, Frida Fåk, Annica Andersson, Sara H Windahl, Helen H. Farman, Sofia Movérare-Skrtic, Ulrika Islander, Klara Sjögren
PloS one - 2014 -
Role of Androgen and Estrogen Receptors for the Action of Dehydroepiandrosterone
(DHEA)
Cecilia Engdahl, Marie K Lagerquist, Alexandra Stubelius, Annica Andersson, Erik Studer, Claes Ohlsson, Lars Westberg, Hans Carlsten, Helena Forsblad d'Elia
Endocrinology - 2014 -
The role of activation functions 1 and 2 of estrogen receptor-alpha for the effects of estradiol and selective estrogen receptor modulators in male
mice
Anna E Börjesson, Helen H. Farman, Cecilia Engdahl, A. Koskela, Klara Sjögren, Jenny Kindblom, Alexandra Stubelius, Ulrika Islander, Hans Carlsten, M. C. Antal, A. Krust, P. Chambon, J. Tuukkanen, Marie K Lagerquist, Sara H Windahl, Claes Ohlsson
Journal of Bone and Mineral Research - 2013 -
Periarticular bone loss in antigen-induced
arthritis.
Cecilia Engdahl, Catharina Lindholm, Alexandra Stubelius, Claes Ohlsson, Hans Carlsten, Marie Lagerquist
Arthritis and rheumatism - 2013 -
Estrogen receptor-alpha in osteocytes is important for trabecular bone formation in male
mice
Sara H Windahl, Anna E Börjesson, Helen H. Farman, Cecilia Engdahl, Sofia Movérare-Skrtic, Klara Sjögren, Marie Lagerquist, Jenny Kindblom, A. Koskela, J. Tuukkanen, P. D. Pajevic, J. Q. Feng, K. Dahlman-Wright, P. Antonson, J. A. Gustafsson, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2013 -
Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not
2.
Sara H Windahl, L Saxon, Anna E Börjesson, Marie Lagerquist, B Frenkel, Petra Henning, Ulf H Lerner, Gl Galea, Lb Meakin, Cecilia Engdahl, Klara Sjögren, Mc Antal, A Krust, P Chambon, LE Lanyon, Js Price, Claes Ohlsson
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2013 -
Exosomal secretion of death bullets: a new way of apoptotic
escape?
N. Trokovic, R. Pollanen, P. Porola, V. Stegaev, U. Hetzel, Åsa Tivesten, Cecilia Engdahl, Hans Carlsten, Helena Forsblad d'Elia, Johan Bourghardt Fagman, Marie Lagerquist, Y. T. Konttinen
American Journal of Physiology-Endocrinology and Metabolism - 2012 -
Arthritis and immune-mediated bone loss - role of estrogen signalling
pathways
Cecilia Engdahl
2012 -
The role of estrogen receptor-alpha and its activation function-1 for growth plate closure in female
mice
Anna E Börjesson, Sara H Windahl, E. Karimian, E. E. Eriksson, Marie Lagerquist, Cecilia Engdahl, M. C. Antal, A. Krust, P. Chambon, L. Savendahl, Claes Ohlsson
American Journal of Physiology-Endocrinology and Metabolism - 2012 -
The gut microbiota regulates bone mass in
mice
Klara Sjögren, Cecilia Engdahl, Petra Henning, Ulf H Lerner, Valentina Tremaroli, Marie Lagerquist, Fredrik Bäckhed, Claes Ohlsson
Journal of Bone and Mineral Research - 2012 -
Estrogen receptor-α expression in neuronal cells affects bone
mass.
Claes Ohlsson, Cecilia Engdahl, Anna E Börjesson, Sara H Windahl, Erik Studer, Lars Westberg, Elias Eriksson, Antti Koskela, Juha Tuukkanen, Andree Krust, Pierre Chambon, Hans Carlsten, Marie Lagerquist
Proceedings of the National Academy of Sciences of the United States of America - 2012 -
Effects of oestradiol and raloxifene on the induction and effector phases of experimental postmenopausal arthritis and secondary
osteoporosis
Caroline Jochems, Ulrika Islander, Malin Erlandsson, Cecilia Engdahl, Marie Lagerquist, Claes Ohlsson, Kutty Selva Nandakumar, Rikard Holmdahl, Hans Carlsten
Clinical and Experimental Immunology - 2011 -
Roles of transactivating functions 1 and 2 of estrogen receptor-alpha in
bone.
Anna E Börjesson, Sara H Windahl, Marie Lagerquist, Cecilia Engdahl, B Frenkel, Sofia Movérare-Skrtic, Klara Sjögren, Jenny Kindblom, Alexandra Stubelius, Ulrika Islander, Mc Antal, A Krust, P Chambon, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2011 -
Role of endogenous and exogenous female sex hormones in arthritis and osteoporosis development in B10.Q-ncf1*/* mice with collagen-induced chronic
arthritis.
Caroline Jochems, Ulrika Islander, Malin Erlandsson, Cecilia Engdahl, Marie Lagerquist, Inger Gjertsson, Claes Ohlsson, Rikard Holmdahl, Hans Carlsten
BMC musculoskeletal disorders - 2010 -
Amelioration of collagen-induced arthritis and immune-associated bone loss through signaling via estrogen receptor alpha, and not estrogen receptor beta or G protein-coupled receptor
30.
Cecilia Engdahl, Caroline Jochems, Sara H Windahl, Anna E Börjesson, Claes Ohlsson, Hans Carlsten, Marie Lagerquist
Arthritis and rheumatism - 2010 -
In Vivo activation of gene transcription via estrogen response elements by raloxifene
analogue.
Cecilia Engdahl, Caroline Jochems, Gustafsson, van der Saag, Hans Carlsten, Marie Lagerquist
The Journal of endocrinology - 2009