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- Sofia Moverare Skrtic
Sofia Moverare Skrtic
Professor
Department of Internal Medicine and Clinical NutritionAbout Sofia Moverare Skrtic
Associate professor Sofia Movérare-Skrtic’s main focus is to study a previously unknown protein - WNT16 - which has been found to have a specific and very important role for the cortical bone. She is now working intensively to try to understand the mechanisms of action of this protein and how this protein is regulated. Increased knowledge about WNT16 opens new avenues for the specific prevention and treatment of nonvertebral fractures, a substantial unmet medical need.
Sofia Movérare-Skrtic is founded by the Swedish Research Council and in 2015 she was appointed The Novo Nordisk Foundation Excellence Award.
She has also been awarded a 5-year Future Research Leader grant by the Swedish Foundation for Strategic Research.
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GREM2 inactivation increases trabecular bone mass in
mice
Karin H. Nilsson, Petra Henning, Jianyao Wu, Klara Sjögren, Ulf H Lerner, Claes Ohlsson, Sofia Moverare-Skrtic
SCIENTIFIC REPORTS - 2024 -
Toll-like receptor-2 induced inflammation causes local bone formation and activates canonical Wnt
signaling.
Petra Henning, Ali Kassem, Anna Westerlund, Pernilla Lundberg, Cecilia Engdahl, Vikte Lionikaite, Pernilla Wikström, Jianyao Wu, Lei Li, Catharina Lindholm, Pedro P C de Souza, Sofia Movérare-Skrtic, Ulf H Lerner
Frontiers in immunology - 2024 -
The novel cytotoxic polybisphosphonate osteodex decreases bone resorption by enhancing cell death of mature osteoclasts without affecting osteoclastogenesis of RANKL-stimulated mouse bone marrow
macrophages
Petra Henning, Anna Westerlund, Sofia Moverare-Skrtic, Catharina Lindholm, Marcela Marquez-Mendez, Sten Nilsson, Anders R. Holmberg, Ulf H Lerner
INVESTIGATIONAL NEW DRUGS - 2024 -
B4GALNT3 regulates glycosylation of sclerostin and bone
mass
Sofia Moverare-Skrtic, J. Voelkl, Karin H. Nilsson, Maria Nethander, T. T. D. Luong, I. Alesutan, Lei Li, Jianyao Wu, Karin L Horkeby, Marie K Lagerquist, A. Koskela, J. Tuukkanen, J. H. Tobias, Ulf H Lerner, Petra Henning, Claes Ohlsson
eBioMedicine - 2023 -
Osteoprotective effect by interleukin-4 (IL-4) on lipoprotein-induced
periodontitis
Jorge F. Lima Teixeira, Petra Henning, Fernando A. Cintra Magalhães, Glaucia Coletto-Nunes, Thais Floriano-Marcelino, Anna Westerlund, Sofia Movérare-Skrtic, Guilherme J.P.L. Oliveira, Ulf H Lerner, Pedro Paulo C. Souza
Cytokine - 2023 -
An atlas of genetic determinants of forearm
fracture.
Maria Nethander, Sofia Movérare-Skrtic, Anders Kämpe, Eivind Coward, Ene Reimann, Louise Grahnemo, Éva Borbély, Zsuzsanna Helyes, Thomas Funck-Brentano, Martine Cohen-Solal, Juha Tuukkanen, Antti Koskela, Jianyao Wu, Lei Li, Tianyuan Lu, Maiken E Gabrielsen, Reedik Mägi, Mari Hoff, Ulf H Lerner, Petra Henning, Henrik Ullum, Christian Erikstrup, Søren Brunak, Arnulf Langhammer, Tiinamaija Tuomi, Asmundur Oddsson, Kari Stefansson, Ulrika Pettersson-Kymmer, Sisse Rye Ostrowski, Ole Birger Vesterager Pedersen, Unnur Styrkarsdottir, Outi Mäkitie, Kristian Hveem, J Brent Richards, Claes Ohlsson
Nature genetics - 2023 -
Membrane estrogen receptor alpha signaling modulates the sensitivity to estradiol treatment in a dose- and tissue- dependent
manner
Yiwen Jiang, Karin L Horkeby, Petra Henning, Jianyao Wu, Lina Lawenius, Cecilia Engdahl, Priti Gupta, Sofia Moverare-Skrtic, Karin H. Nilsson, E. Levin, Claes Ohlsson, Marie K Lagerquist
Scientific Reports - 2023 -
Bone-Derived IGF-I Regulates Radial Bone Growth in Adult Male
Mice
Johan Svensson, Klara Sjögren, Lina Lawenius, A. Koskela, J. Tuukkanen, Karin H. Nilsson, Sofia Moverare-Skrtic, Claes Ohlsson
Endocrinology - 2023 -
Development of a synbiotic that protects against ovariectomy-induced trabecular bone
loss
Lina Lawenius, Karin L. Gustafsson, Jianyao Wu, Karin H. Nilsson, Sofia Moverare-Skrtic, E. M. Schott, M. J. Soto-Giron, G. V. Toledo, Klara Sjögren, Claes Ohlsson
American Journal of Physiology-Endocrinology and Metabolism - 2022 -
Phosphorylation of S122 in ERα is important for the skeletal response to estrogen treatment in male
mice
Karin L Horkeby, Helen H. Farman, Sofia Movérare-Skrtic, Vikte Lionikaite, Jianyao Wu, Petra Henning, Sara H Windahl, Klara Sjögren, Claes Ohlsson, Marie K Lagerquist
Scientific Reports - 2022 -
Induced inactivation of Wnt16 in young adult mice has no impact on osteoarthritis
development.
Anna E Törnqvist, Karin H. Nilsson, Lei Li, Claes Ohlsson, Sofia Movérare-Skrtic
PloS one - 2022 -
A tissue-specific role of membrane-initiated ERα signaling for the effects of
SERMs
Karin L. Gustafsson, Sofia Movérare-Skrtic, Helen H. Farman, Cecilia Engdahl, Petra Henning, Karin H. Nilsson, Julia M. Scheffler, Edina Sehic, Ulrika Islander, E. Levin, Claes Ohlsson, Marie K Lagerquist
Journal of Endocrinology - 2022 -
GWAS META-analysis followed by MENDELIAN randomisation revealed potential control mechanisms for circulating α-klotho
levels.
Ingrid Gergei, Jie Zheng, Till F M Andlauer, Vincent Brandenburg, Nazanin Mirza-Schreiber, Bertram Müller-Myhsok, Bernhard K Krämer, Daniel Richard, Louise Falk, Sofia Movérare-Skrtic, Claes Ohlsson, George Davey Smith, Winfried März, Jakob Voelkl, Jonathan H Tobias
Human molecular genetics - 2022 -
Estradiol and RSPO3 regulate vertebral trabecular bone mass independent of each
other
Karin H. Nilsson, Jianyao Wu, Karin L. Gustafsson, Maha El Shahawy, A. Koskela, J. Tuukkanen, J. Tuckermann, Petra Henning, Ulf H Lerner, Claes Ohlsson, Sofia Movérare-Skrtic
American journal of physiology. Endocrinology and metabolism - 2022 -
WNT16 is Robustly Increased by Oncostatin M in Mouse Calvarial Osteoblasts and Acts as a Negative Feedback Regulator of Osteoclast Formation Induced by Oncostatin
M
Petra Henning, Sofia Moverare-Skrtic, Anna Westerlund, P. P. C. de Souza, T. Floriano-Marcelino, Karin H. Nilsson, Maha El Shahawy, Claes Ohlsson, Ulf H Lerner
Journal of Inflammation Research - 2021 -
Mild stimulatory effect of a probiotic mix on bone mass when treatment is initiated 1.5 weeks after ovariectomy in
mice
Claes Ohlsson, Lina Lawenius, Annica Andersson, Karin L. Gustafsson, Jianyao Wu, Marie Lagerquist, Sofia Moverare-Skrtic, Ulrika Islander, Klara Sjögren
American Journal of Physiology-Endocrinology and Metabolism - 2021 -
Osteocyte- and late osteoblast-derived NOTUM reduces cortical bone mass in
mice
Karin H. Nilsson, Petra Henning, Maha El Shahawy, Jianyao Wu, A. Koskela, J. Tuukkanen, C. Perret, Ulf H Lerner, Claes Ohlsson, Sofia Moverare-Skrtic
American Journal of Physiology-Endocrinology and Metabolism - 2021 -
Arginine site 264 in murine estrogen receptor alpha is dispensable for the regulation of the
skeleton.
Karin L. Gustafsson, Helen H. Farman, Karin H. Nilsson, Petra Henning, Sofia Movérare-Skrtic, Vikte Lionikaite, Lina Lawenius, Cecilia Engdahl, Claes Ohlsson, Marie K Lagerquist
American journal of physiology. Endocrinology and metabolism - 2021 -
RSPO3 is important for trabecular bone and fracture risk in mice and
humans
Karin H. Nilsson, Petra Henning, Maha El Shahawy, Maria Nethander, T. L. Andersen, C. Ejersted, Jianyao Wu, Karin L. Gustafsson, A. Koskela, J. Tuukkanen, P. P. C. Souza, J. Tuckermann, Mattias Lorentzon, Linda Engström-Ruud, T. Lehtimaki, J. H. Tobias, S. R. Zhou, Ulf H Lerner, J. B. Richards, Sofia Moverare-Skrtic, Claes Ohlsson
Nature Communications - 2021 -
Wnt16 Overexpression in Osteoblasts Increases the Subchondral Bone Mass but has no Impact on Osteoarthritis in Young Adult Female
Mice
Anna E Törnqvist, Louise Grahnemo, Karin H. Nilsson, Thomas Funck-Brentano, Claes Ohlsson, Sofia Movérare-Skrtic
Calcified Tissue International - 2020 -
Phosphorylation site S122 in estrogen receptor α has a tissue-dependent role in female
mice
Claes Ohlsson, Karin L. Gustafsson, Helen H. Farman, Petra Henning, Vikte Lionikaite, Sofia Movérare-Skrtic, Klara Sjögren, Anna E Törnqvist, Annica Andersson, Ulrika Islander, Angelina I Bernardi, Matti Poutanen, Pierre Chambon, Marie K Lagerquist
FASEB Journal - 2020 -
The effects of estradiol are modulated in a tissue-specific manner in mice with inducible inactivation of ERα after sexual
maturation.
Claes Ohlsson, Helen H. Farman, Karin L. Gustafsson, Jianyao Wu, Petra Henning, Sara H Windahl, Klara Sjögren, Jan-Åke Gustafsson, Sofia Movérare-Skrtic, Marie Lagerquist
American journal of physiology. Endocrinology and metabolism - 2020 -
Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and
Fractures
J. Zheng, W. Maerz, I. Gergei, M. Kleber, C. Drechsler, C. Wanner, V. Brandenburg, S. Reppe, K. M. Gautvik, C. Medina-Gomez, E. Shevroja, A. Gilly, Y. C. Park, G. Dedoussis, E. Zeggini, Mattias Lorentzon, Petra Henning, Ulf H Lerner, Karin H. Nilsson, Sofia Moverare-Skrtic, D. Baird, B. Elsworth, L. Falk, A. Groom, T. D. Capellini, E. Grundberg, Maria Nethander, Claes Ohlsson, G. D. Smith, J. H. Tobias
Journal of Bone and Mineral Research - 2019 -
Causal Factors for Knee, Hip, and Hand Osteoarthritis: A Mendelian Randomization Study in the UK
Biobank
Thomas Funck-Brentano, Maria Nethander, Sofia Moverare-Skrtic, P. Richette, Claes Ohlsson
Arthritis & Rheumatology - 2019 -
Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in
humans
Sofia Moverare-Skrtic, Karin H. Nilsson, Petra Henning, Thomas Funck-Brentano, Maria Nethander, F. Rivadeneira, G. C. Nunes, A. Koskela, J. Tuukkanen, J. Tuckermann, C. Perret, P. P. C. Souza, Ulf H Lerner, Claes Ohlsson
Faseb Journal - 2019 -
NOTUM inhibition increases endocortical bone formation and bone
strength
Robert Brommage, J. Liu, P. Vogel, F. Mseeh, A. Y. Thompson, D. G. Potter, M. K. Shadoan, G. M. Hansen, S. Jeter-Jones, J. Cui, D. Bright, J. P. Bardenhagen, D. D. Doree, Sofia Moverare-Skrtic, Karin H. Nilsson, Petra Henning, Ulf H Lerner, Claes Ohlsson, A. T. Sands, J. E. Tarver, D. R. Powell, B. Zambrowicz, Q. Y. Liu
Bone Research - 2019 -
The androgen receptor is required for maintenance of bone mass in adult male
mice.
Jianyao Wu, Petra Henning, Klara Sjögren, Antti Koskela, Juha Tuukkanen, Sofia Movérare-Skrtic, Claes Ohlsson
Molecular and cellular endocrinology - 2019 -
Androgen receptor SUMOylation regulates bone mass in male
mice
Jianyao Wu, Sofia Moverare-Skrtic, F. P. Zhang, A. Koskela, J. Tuukkanen, J. J. Palvimo, P. Sipila, Matti Poutanen, Claes Ohlsson
Molecular and Cellular Endocrinology - 2019 -
Porcupine inhibitors impair trabecular and cortical bone mass and strength in
mice
Thomas Funck-Brentano, Karin H. Nilsson, Robert Brommage, Petra Henning, Ulf H Lerner, A. Koskela, J. Tuukkanen, M. Cohen-Solal, Sofia Moverare-Skrtic, Claes Ohlsson
Journal of Endocrinology - 2018 -
WNT16 overexpression partly protects against glucocorticoid-induced bone
loss
Claes Ohlsson, Karin H. Nilsson, Petra Henning, Jianyao Wu, Karin L. Gustafsson, Matti Poutanen, Ulf H Lerner, Sofia Moverare-Skrtic
American Journal of Physiology-Endocrinology and Metabolism - 2018 -
Membrane estrogen receptor alpha is essential for estrogen signaling in the male
skeleton
Helen H. Farman, Karin L. Gustafsson, Petra Henning, Louise Grahnemo, Vikte Lionikaite, Sofia Moverare-Skrtic, Jianyao Wu, Henrik Ryberg, A. Koskela, J. Tuukkanen, E. R. Levin, Claes Ohlsson, Marie Lagerquist
Journal of Endocrinology - 2018 -
ER alpha expression in T lymphocytes is dispensable for estrogenic effects in
bone
Karin L. Gustafsson, Karin H. Nilsson, Helen H. Farman, Vikte Lionikaite, Petra Henning, Jianyao Wu, Sara H Windahl, Ulrika Islander, Sofia Moverare-Skrtic, Klara Sjögren, Hans Carlsten, Claes Ohlsson, Marie Lagerquist
Journal of Endocrinology - 2018 -
Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult
mice.
Claes Ohlsson, Petra Henning, Karin H. Nilsson, Jianyao Wu, Karin L. Gustafsson, Klara Sjögren, Anna E Törnqvist, Antti Koskela, Fu-Ping Zhang, Marie Lagerquist, Matti Poutanen, Juha Tuukkanen, Ulf H Lerner, Sofia Movérare-Skrtic
The Journal of endocrinology - 2018 -
Roles of activating functions 1 and 2 of estrogen receptor α in
lymphopoiesis.
Annica Andersson, Sofia Movérare-Skrtic, Angelina I Bernardi, Helen H. Farman, Pierre Chambon, Cecilia Engdahl, Marie Lagerquist, Sara H Windahl, Hans Carlsten, Claes Ohlsson, Ulrika Islander
The Journal of endocrinology - 2018 -
Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male
mice.
Claes Ohlsson, Ann Hammarstedt, Liesbeth Vandenput, Niina Saarinen, Henrik Ryberg, Sara H Windahl, Helen H. Farman, John-Olov Jansson, Sofia Movérare-Skrtic, Ulf Smith, Fu-Ping Zhang, Matti Poutanen, Shahram Hedjazifar, Klara Sjögren
American journal of physiology. Endocrinology and metabolism - 2017 -
Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin
resistance.
John Grünberg, Jenny M Hoffmann, Shahram Hedjazifar, Annika Nerstedt, Lachmi E Jenndahl, Johannes Elvin, John Castellot, Lan Wei, Sofia Movérare-Skrtic, Claes Ohlsson, Louise Mannerås Holm, Fredrik Bäckhed, Ismail Syed, Fatima Bosch, Alan Saghatelian, Barbara B Kahn, Ann Hammarstedt, Ulf Smith
Scientific reports - 2017 -
SERMs have substance-specific effects on bone, and these effects are mediated via ER alpha AF-1 in female
mice
Anna E Börjesson, Helen H. Farman, Sofia Movérare-Skrtic, Cecilia Engdahl, M. C. Antal, A. Koskela, J. Tuukkanen, Hans Carlsten, A. Krust, P. Chambon, Klara Sjögren, Marie K Lagerquist, Sara H Windahl, Claes Ohlsson
American Journal of Physiology-Endocrinology and Metabolism - 2016 -
The role of membrane ER alpha signaling in bone and other major estrogen responsive
tissues
Karin L. Gustafsson, Helen H. Farman, Petra Henning, Vikte Lionikaite, Sofia Movérare-Skrtic, Jianyao Wu, Henrik Ryberg, A. Koskela, J. A. Gustafsson, J. Tuukkanen, E. R. Levin, Claes Ohlsson, Marie K Lagerquist
Scientific Reports - 2016 -
Enzalutamide Reduces the Bone Mass in the Axial but not the Appendicular Skeleton in Male
Mice.
Jianyao Wu, Sofia Movérare-Skrtic, Anna E Börjesson, Marie K Lagerquist, Klara Sjögren, Sara H Windahl, Antti Koskela, Louise Grahnemo, Ulrika Islander, Anna S K Wilhelmson, Åsa Tivesten, Juha Tuukkanen, Claes Ohlsson
Endocrinology - 2016 -
The bone-sparing effects of estrogen and WNT16 are independent of each
other
Sofia Movérare-Skrtic, Jianyao Wu, Petra Henning, Karin L. Gustafsson, Klara Sjögren, Sara H Windahl, A. Koskela, J. Tuukkanen, Anna E Börjesson, Marie K Lagerquist, Ulf H Lerner, F.P. Zhang, J.Å. Gustafsson, Matti Poutanen, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2015 -
Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility
fractures.
Sofia Movérare-Skrtic, Petra Henning, Xianwen Liu, Kenichi Nagano, Hiroaki Saito, Anna E Börjesson, Klara Sjögren, Sara H Windahl, Helen H. Farman, Bert Kindlund, Cecilia Engdahl, Antti Koskela, Fu-Ping Zhang, Emma E Eriksson, Farasat Zaman, Ann Hammarstedt, Hanna Isaksson, Marta Bally, Ali Kassem, Catharina Lindholm, Olof Sandberg, Per Aspenberg, Lars Sävendahl, Jian Q Feng, Jan Tuckermann, Juha Tuukkanen, Matti Poutanen, Roland Baron, Ulf H Lerner, Francesca Gori, Claes Ohlsson
Nature Medicine - 2014 -
Laminin alpha 4 Deficient Mice Exhibit Decreased Capacity for Adipose Tissue Expansion and Weight
Gain
M. K. Vaicik, J. T. Kortesmaa, Sofia Movérare-Skrtic, J. Kortesmaa, R. Soininen, G. Bergstrom, Claes Ohlsson, L. Y. Chong, B. Rozell, M. Emont, R. N. Cohen, E. M. Brey, K. Tryggvason
Plos One - 2014 -
Leukocyte telomere length is not associated with mortality in older
men
Johan Svensson, M. K. Karlsson, O. Ljunggren, Åsa Tivesten, Dan Mellström, Sofia Movérare-Skrtic
Experimental Gerontology - 2014 -
Probiotics protect mice from ovariectomy-induced cortical bone
loss.
Claes Ohlsson, Cecilia Engdahl, Frida Fåk, Annica Andersson, Sara H Windahl, Helen H. Farman, Sofia Movérare-Skrtic, Ulrika Islander, Klara Sjögren
PloS one - 2014 -
High sensitive CRP is an independent risk factor for all fractures and vertebral fractures in elderly men: The MrOS Sweden
study.
Anna-Lena Eriksson, Sofia Movérare-Skrtic, Osten Ljunggren, Magnus Karlsson, Dan Mellström, Claes Ohlsson
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2014 -
The estrogen receptor antagonist ICI 182,780 can act both as an agonist and an inverse agonist when estrogen receptor α AF-2 is
modified.
Sofia Movérare-Skrtic, Anna E Börjesson, Helen H. Farman, Klara Sjögren, Sara H Windahl, Marie K Lagerquist, Annica Andersson, Alexandra Stubelius, Hans Carlsten, Jan-Åke Gustafsson, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2014 -
Estrogen receptor-alpha in osteocytes is important for trabecular bone formation in male
mice
Sara H Windahl, Anna E Börjesson, Helen H. Farman, Cecilia Engdahl, Sofia Movérare-Skrtic, Klara Sjögren, Marie Lagerquist, Jenny Kindblom, A. Koskela, J. Tuukkanen, P. D. Pajevic, J. Q. Feng, K. Dahlman-Wright, P. Antonson, J. A. Gustafsson, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2013 -
WNT16 Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture
Risk.
Hou-Feng Zheng, Jon H Tobias, Emma Duncan, David M Evans, Joel Eriksson, Lavinia Paternoster, Laura M Yerges-Armstrong, Terho Lehtimäki, Ulrica Bergström, Mika Kähönen, Paul J Leo, Olli Raitakari, Marika Laaksonen, Geoffrey C Nicholson, Jorma Viikari, Martin Ladouceur, Leo-Pekka Lyytikäinen, Carolina Medina-Gomez, Fernando Rivadeneira, Richard L Prince, Harri Sievanen, William D Leslie, Dan Mellström, John A Eisman, Sofia Movérare-Skrtic, David Goltzman, David A Hanley, Graeme Jones, Beate St Pourcain, Yongjun Xiao, Nicholas J Timpson, George Davey Smith, Ian R Reid, Susan M Ring, Philip N Sambrook, Magnus Karlsson, Elaine M Dennison, John P Kemp, Patrick Danoy, Adrian Sayers, Scott G Wilson, Maria Nethander, Eugene McCloskey, Liesbeth Vandenput, Richard Eastell, Jeff Liu, Tim Spector, Braxton D Mitchell, Elizabeth A Streeten, Robert Brommage, Ulrika Pettersson-Kymmer, Matthew A Brown, Claes Ohlsson, J Brent Richards, Mattias Lorentzon
PLoS genetics - 2012 -
Leukocyte Telomere Length (LTL) is reduced in stable mild cognitive impairment but low LTL is not associated with conversion to Alzheimer's Disease: A pilot
study.
Sofia Movérare-Skrtic, Per Johansson, Niklas Mattsson, Oskar Hansson, Anders Wallin, Jan-Ove Johansson, Henrik Zetterberg, Kaj Blennow, Johan Svensson
Experimental gerontology - 2012 -
Roles of transactivating functions 1 and 2 of estrogen receptor-alpha in
bone.
Anna E Börjesson, Sara H Windahl, Marie Lagerquist, Cecilia Engdahl, B Frenkel, Sofia Movérare-Skrtic, Klara Sjögren, Jenny Kindblom, Alexandra Stubelius, Ulrika Islander, Mc Antal, A Krust, P Chambon, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2011 -
Reduced bone mass and muscle strength in male 5α-reductase type 1 inactivated
mice.
Sara H Windahl, Niklas Andersson, Anna E Börjesson, Charlotte Swanson, Johan Svensson, Sofia Movérare-Skrtic, Klara Sjögren, Linus Ruijin Shao, Marie Lagerquist, Claes Ohlsson
PloS one - 2011 -
Stimulation of both estrogen and androgen receptors maintains skeletal muscle mass in gonadectomized male mice but mainly via different
pathways.
Johan Svensson, Sofia Movérare-Skrtic, Sara H Windahl, Charlotte Swanson, Klara Sjögren
Journal of molecular endocrinology - 2010 -
The role of estrogen receptor-alpha in growth plate cartilage for longitudinal bone
growth.
Anna E Börjesson, Marie Lagerquist, C Liu, Linus Ruijin Shao, Sara H Windahl, Camilla Karlsson, Klara Sjögren, Sofia Movérare-Skrtic, Mc Antal, A Krust, Subburaman Mohan, P Chambon, Lars Sävendahl, Claes Ohlsson
Journal of bone and mineral research - 2010 -
Serum insulin-like growth factor-I concentration is associated with leukocyte telomere length in a population-based cohort of elderly
men.
Sofia Movérare-Skrtic, Johan Svensson, Magnus K Karlsson, Eric Orwoll, Osten Ljunggren, Dan Mellström, Claes Ohlsson
The Journal of clinical endocrinology and metabolism - 2009 -
Elevated Aromatase Expression in Osteoblasts Leads to Increased Bone Mass without Systemic Adverse
Effects.
Klara Sjögren, Marie Lagerquist, Sofia Movérare-Skrtic, Niklas Andersson, Sara H Windahl, Charlotte Swanson, Subburaman Mohan, M Poutanen, Claes Ohlsson
Journal of bone and mineral research - 2009 -
The role of the G protein-coupled receptor GPR30 in the effects of estrogen in ovariectomized
mice.
Sara H Windahl, Niklas Andersson, A S Chagin, U E A Mårtensson, Hans Carlsten, B Olde, Charlotte Swanson, Sofia Movérare-Skrtic, L Sävendahl, Marie Lagerquist, L M F Leeb-Lundberg, Claes Ohlsson
American journal of physiology. Endocrinology and metabolism - 2009 -
Peripheral blood leukocyte distribution and body mass index are associated with the methylation pattern of the androgen receptor
promoter.
Sofia Movérare-Skrtic, Dan Mellström, Liesbeth Vandenput, M Ehrich, Claes Ohlsson
Endocrine - 2009 -
Liver-derived IGF1 enhances the androgenic response in
prostate.
Johan Svensson, Jon Kindblom, Linus Ruijin Shao, Sofia Movérare-Skrtic, Marie Lagerquist, Niklas Andersson, Klara Sjögren, Katrien Venken, Dirk Vanderschueren, John-Olov Jansson, Olle Isaksson, Claes Ohlsson
The Journal of endocrinology - 2008 -
Attainment of brown adipocyte features in white adipocytes of hormone-sensitive lipase null
mice.
Kristoffer Ström, Ola Hansson, Stéphanie Lucas, Pernilla Nevsten, Céline Fernandez, Cecilia Klint, Sofia Movérare-Skrtic, Frank Sundler, Claes Ohlsson, Cecilia Holm
PLoS ONE - 2008 -
Impact of androgens, growth hormone, and IGF-I on bone and muscle in male mice during
puberty.
Katrien Venken, Sofia Movérare-Skrtic, John J Kopchick, Karen T Coschigano, Claes Ohlsson, Steven Boonen, Roger Bouillon, Dirk Vanderschueren
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2007 -
Dihydrotestosterone treatment results in obesity and altered lipid metabolism in orchidectomized
mice.
Sofia Movérare-Skrtic, Katrien Venken, Niklas Andersson, Marie K Lindberg, Johan Svensson, Charlotte Swanson, Dirk Vanderschueren, Jan Oscarsson, Jan-Ake Gustafsson, Claes Ohlsson
Obesity (Silver Spring, Md.) - 2006 -
Liver-derived IGF-I is permissive for ovariectomy-induced trabecular bone
loss
Marie Lindberg, J. Svensson, K. Venken, Tina Chavoshi, Niklas Andersson, Sofia Movérare-Skrtic, Olle Isaksson, D. Vanderschueren, Hans Carlsten, Claes Ohlsson
Bone - 2006 -
Leukemia inhibitory factor reduces body fat mass in ovariectomized
mice
John-Olov Jansson, Sofia Movérare-Skrtic, Anna Berndtsson, Ingrid Wernstedt, Hans Carlsten, Claes Ohlsson
Eur J Endocrinol - 2006 -
A gene expression fingerprint of mouse stomach ECL
cells.
Niklas Andersson, Sofia Movérare-Skrtic, Rolf Håkanson, Claes Ohlsson
Biochemical and biophysical research communications - 2005 -
Increased adipogenesis in bone marrow but decreased bone mineral density in mice devoid of thyroid hormone
receptors.
Jenny Kindblom, Evelien F Gevers, Sofia Movérare-Skrtic, Marie K Lindberg, Sten Göthe, Jan Törnell, Björn Vennström, Claes Ohlsson
Bone - 2005 -
Estren promotes androgen phenotypes in primary lymphoid organs and submandibular
glands
Ulrika Islander, Bengt Hasséus, Malin Erlandsson, Caroline Jochems, Sofia Movérare-Skrtic, Marie Lindberg, J. A. Gustafsson, Claes Ohlsson, Hans Carlsten
BMC Immunology - 2005 -
Androgens and the
skeleton.
Marie Lagerquist, Liesbeth Vandenput, Sofia Movérare-Skrtic, Dirk Vanderschueren, Steven Boonen, Roger Bouillon, Claes Ohlsson
Minerva endocrinologica - 2005 -
Estren-mediated inhibition of T lymphopoiesis is estrogen receptor-independent whereas its suppression of T cell-mediated inflammation is estrogen
receptor-dependent
Ulrika Islander, Malin Erlandsson, Tina Chavoshi, Caroline Jochems, Sofia Movérare-Skrtic, S. Nilsson, Claes Ohlsson, J. A. Gustafsson, Hans Carlsten
Clin Exp Immunol - 2005 -
Investigation of central versus peripheral effects of estradiol in ovariectomized
mice
Niklas Andersson, Ulrika Islander, Emil Egecioglu, Elin Löf, Charlotte Swanson, Sofia Movérare-Skrtic, Klara Sjögren, Marie Lindberg, Hans Carlsten, Claes Ohlsson
J Endocrinol - 2005 -
Estrogenic agonism and antagonism of the soy isoflavone genistein in uterus, bone and lymphopoiesis in
mice
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The relative importance of sex steroid receptors for bone
metabolism
-
Proteome analysis for the identification of in vivo estrogen-regulated proteins in
bone.
Roberta Pastorelli, Donatella Carpi, Luisa Airoldi, Chiara Chiabrando, Renzo Bagnati, Roberto Fanelli, Sofia Movérare-Skrtic, Claes Ohlsson
Proteomics - 2005 -
Growth without growth hormone receptor: estradiol is a major growth hormone-independent regulator of hepatic IGF-I
synthesis.
Katrien Venken, Frans Schuit, Leentje Van Lommel, Katsura Tsukamoto, John J Kopchick, Karen T Coschigano, Claes Ohlsson, Sofia Movérare-Skrtic, Steven Boonen, Roger Bouillon, Dirk Vanderschueren
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2005 -
Gene expression profiling identifies liver X receptor alpha as an estrogen-regulated gene in mouse adipose
tissue.
Lovisa Lundholm, Sofia Movérare, K R Steffensen, M Nilsson, Michio Otsuki, Claes Ohlsson, J-A Gustafsson, Karin Dahlman-Wright
Journal of molecular endocrinology - 2004 -
Additive protective effects of estrogen and androgen treatment on trabecular bone in ovariectomized
rats.
Åsa Tivesten, Sofia Movérare-Skrtic, Andrei Chagin, Katrien Venken, Phil Salmon, Dirk Vanderschueren, Lars Sävendahl, Agneta Holmäng, Claes Ohlsson
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2004 -
Estrogen receptor-beta inhibits skeletal growth and has the capacity to mediate growth plate fusion in female
mice.
A S Chagin, Marie K Lindberg, Niklas Andersson, Sofia Movérare-Skrtic, J A Gustafsson, Lars Sävendahl, Claes Ohlsson
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2004 -
Estrogen increases coagulation factor V mRNA levels via both estrogen receptor-alpha and -beta in murine bone
marrow/bone.
Sofia Movérare, Stanko Skrtic, Marie K Lindberg, Karin Dahlman-Wright, Claes Ohlsson
European journal of endocrinology / European Federation of Endocrine Societies - 2004 -
Estrogen up-regulates hepatic expression of suppressors of cytokine signaling-2 and -3 in vivo and in
vitro.
Gary M Leong, Sofia Movérare-Skrtic, Jesena Brce, Nathan Doyle, Klara Sjögren, Karin Dahlman-Wright, Jan-Ake Gustafsson, Ken K Y Ho, Claes Ohlsson, Kin-Chuen Leung
Endocrinology - 2004 -
Estren is a selective estrogen receptor modulator with transcriptional
activity.
Sofia Movérare, Johanna Dahllund, Niklas Andersson, Ulrika Islander, Hans Carlsten, Jan-Ake Gustafsson, Stefan Nilsson, Claes Ohlsson
Molecular pharmacology - 2003 -
Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang" relationship between ERalpha and ERbeta in
mice.
Marie K Lindberg, Sofia Movérare, Stanko Skrtic, Hui-Ling Gao, Karin Dahlman-Wright, Jan-Ake Gustafsson, Claes Ohlsson
Molecular endocrinology (Baltimore, Md.) - 2003 -
Differential effects on bone of estrogen receptor alpha and androgen receptor activation in orchidectomized adult male
mice.
Sofia Movérare, Katrien Venken, Anna-Lena Eriksson, Niklas Andersson, Stanko Skrtic, Jon Wergedal, Subburaman Mohan, Phil Salmon, Roger Bouillon, Jan-Ake Gustafsson, Dirk Vanderschueren, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2003 -
Effects of liver-derived insulin-like growth factor I on bone metabolism in
mice.
Klara Sjögren, Matilda Sheng, Sofia Movérare, Jun-Li Liu, Kristina Wallenius, Jan Törnell, Olle Isaksson, John-Olov Jansson, Subburaman Mohan, Claes Ohlsson
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2002 -
Estrogen receptor specificity for the effects of estrogen in ovariectomized
mice.
Marie K Lindberg, Z Weihua, Niklas Andersson, Sofia Movérare, Hui-Ling Gao, Olle Vidal, M C Erlandsson, Sara H Windahl, G Andersson, D B Lubahn, Hans Carlsten, Karin Dahlman-Wright, J-A Gustafsson, Claes Ohlsson
The Journal of endocrinology - 2002 -
Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the hair follicle cycling as well as the thickness of epidermis in male
mice.
Sofia Movérare, Marie K Lindberg, Jan Faergemann, J-A Gustafsson, Claes Ohlsson
The Journal of investigative dermatology - 2002 -
Identification of estrogen-regulated genes of potential importance for the regulation of trabecular bone mineral
density.
Marie K Lindberg, Sofia Movérare, Anna-Lena Eriksson, Stanko Skrtic, Hui-Ling Gao, Karin Dahlman-Wright, Jan-Ake Gustafsson, Claes Ohlsson
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2002 -
Two different pathways for the maintenance of trabecular bone in adult male
mice.
Marie K Lindberg, Sofia Movérare, Stanko Skrtic, Sari L Alatalo, Jussi M Halleen, Subburaman Mohan, J A Gustafsson, Claes Ohlsson
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2002