University of Gothenburg
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  4. Alessandro Camponeschi

Alessandro Camponeschi

Researcher

Department of Rheumatology and Inflammation Research
Mail
alessandro.camponeschi@rheuma.gu.se
Visiting address
Guldhedsgatan 10A, floor 4
413 46 Göteborg
Postal address
Box 480
40530 Göteborg

About Alessandro Camponeschi

B cells are essential players in adaptive immunity. They produce antibodies, present antigens, coordinate immune responses, and help build long-term immune memory. But when their normal checkpoints fail, B cells can become dangerous. They may turn malignant, giving rise to leukemias and lymphomas, or become autoreactive and contribute to autoimmune disease.

This is why we call ourselves The Rogue Cell Lab: we study B cells that have gone off course.

Our team investigates how B cells become “rogue” in cancer and autoimmunity. In B-cell malignancies, we study how cancerous B cells interact with their microenvironment, evade immune control, and use B-cell receptor signaling to survive, progress, and resist therapy. In autoimmunity, we explore how B-cell tolerance is regulated and how its failure can allow self-reactive B cells to emerge.

Our goal is to understand the mechanisms that turn protective immune cells into drivers of disease, and to use that knowledge to identify better therapeutic strategies.