Karin Nilsson
Doctoral Student
Department of Internal Medicine and ClinicalAbout Karin Nilsson
Karin Nilsson began her PhD-studies at CBAR in May 2016. She graduated from the University of Gothenburg in 2011 with a master of science in pharmacy.
Karin is researching the mechanism by which Wnt16 regulates cortical bone. Wnt16, being a unique and powerful regulator of cortical bone, is of interest when studying possible treatment options for osteoporosis. Today’s treatment against osteoporosis targets mainly trabecular bone, whilst the majority of the fractures associated with osteoporosis is due to reduced cortical bone mass, resulting in a need for novel osteoporosis treatment.
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Arginine site 264 in murine estrogen receptor alpha is dispensable for the regulation of the
skeleton.
Karin L. Gustafsson, Helen H. Farman, Karin H. Nilsson, Petra Henning, Sofia Movérare-Skrtic, Vikte Lionikaite, Lina Lawenius, Cecilia Engdahl, Claes Ohlsson, Marie K Lagerquist
American journal of physiology. Endocrinology and metabolism - 2021-01-01 -
Pasteurized Akkermansia muciniphila protects from fat mass gain but not from bone
loss
Lina Lawenius, Julia M. Scheffler, Karin L. Gustafsson, Petra Henning, Karin H. Nilsson, Hannah Colldén, Ulrika Islander, H. Plovier, P. D. Cani, W. M. de Vos, Claes Ohlsson, Klara Sjögren
American Journal of Physiology-Endocrinology and Metabolism - 2020-01-01 -
Wnt16 Overexpression in Osteoblasts Increases the Subchondral Bone Mass but has no Impact on Osteoarthritis in Young Adult Female
Mice
Anna E Törnqvist, Louise Grahnemo, Karin H. Nilsson, Thomas Funck-Brentano, Claes Ohlsson, Sofia Movérare-Skrtic
Calcified Tissue International - 2020-01-01 -
NOTUM inhibition increases endocortical bone formation and bone
strength
Robert Brommage, J. Liu, P. Vogel, F. Mseeh, A. Y. Thompson, D. G. Potter, M. K. Shadoan, G. M. Hansen, S. Jeter-Jones, J. Cui, D. Bright, J. P. Bardenhagen, D. D. Doree, Sofia Moverare-Skrtic, Karin H. Nilsson, Petra Henning, Ulf H Lerner, Claes Ohlsson, A. T. Sands, J. E. Tarver, D. R. Powell, B. Zambrowicz, Q. Y. Liu
Bone Research - 2019-01-01 -
Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in
humans
Sofia Moverare-Skrtic, Karin H. Nilsson, Petra Henning, Thomas Funck-Brentano, Maria Nethander, F. Rivadeneira, G. C. Nunes, A. Koskela, J. Tuukkanen, J. Tuckermann, C. Perret, P. P. C. Souza, Ulf H Lerner, Claes Ohlsson
Faseb Journal - 2019-01-01 -
Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and
Fractures
J. Zheng, W. Maerz, I. Gergei, M. Kleber, C. Drechsler, C. Wanner, V. Brandenburg, S. Reppe, K. M. Gautvik, C. Medina-Gomez, E. Shevroja, A. Gilly, Y. C. Park, G. Dedoussis, E. Zeggini, Mattias Lorentzon, Petra Henning, Ulf H Lerner, Karin H. Nilsson, Sofia Moverare-Skrtic, D. Baird, B. Elsworth, L. Falk, A. Groom, T. D. Capellini, E. Grundberg, Maria Nethander, Claes Ohlsson, G. D. Smith, J. H. Tobias
Journal of Bone and Mineral Research - 2019-01-01 -
Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult
mice.
Claes Ohlsson, Petra Henning, Karin H. Nilsson, Jianyao Wu, Karin L. Gustafsson, Klara Sjögren, Anna E Törnqvist, Antti Koskela, Fu-Ping Zhang, Marie Lagerquist, Matti Poutanen, Juha Tuukkanen, Ulf H Lerner, Sofia Movérare-Skrtic
The Journal of endocrinology - 2018-01-01 -
Porcupine inhibitors impair trabecular and cortical bone mass and strength in
mice
Thomas Funck-Brentano, Karin H. Nilsson, Robert Brommage, Petra Henning, Ulf H Lerner, A. Koskela, J. Tuukkanen, M. Cohen-Solal, Sofia Moverare-Skrtic, Claes Ohlsson
Journal of Endocrinology - 2018-01-01 -
WNT16 overexpression partly protects against glucocorticoid-induced bone
loss
Claes Ohlsson, Karin H. Nilsson, Petra Henning, Jianyao Wu, Karin L. Gustafsson, Matti Poutanen, Ulf H Lerner, Sofia Moverare-Skrtic
American Journal of Physiology-Endocrinology and Metabolism - 2018-01-01 -
ER alpha expression in T lymphocytes is dispensable for estrogenic effects in
bone
Karin L. Gustafsson, Karin H. Nilsson, Helen H. Farman, Vikte Lionikaite, Petra Henning, Jianyao Wu, Sara H Windahl, Ulrika Islander, Sofia Moverare-Skrtic, Klara Sjögren, Hans Carlsten, Claes Ohlsson, Marie Lagerquist
Journal of Endocrinology - 2018-01-01