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Key Research Areas

Key Areas within the research at the Institute of Biomedicine

The Institute of Biomedicine has a departmental structure consisting of four departments, which creates a critical mass necessary for nationally leading, and internationally competitive research. This structure largely mirrors that of the division of clinical units at Sahlgrenska University Hospital (SU, separate entity from GU), which is one of our largest partners. The close collaboration with SU, which is part of the Västra Götaland region, a county bringing together large parts of Western Sweden, means that our research becomes both nationally and internationally visible and easily applicable. In addition to our advanced translational research, we conduct basic molecular and microbiological, biochemical and medical research at a high international level with many worldwide research collaborations.

 

In our drive to be nationally leading and internationally competitive, we focus on strategies that will develop research environments that suit our defined research areas. The Department of Biomedicine has four main key areas.

 

1. Infection and immunology

2. Cancer and stem cell biology

3. Genetics and molecular medicine

4. Cell and molecular biology, including glycobiology

Research groups in key areas

Ingegerd Adlerberth

Davide Angeletti 
B cell and antibody immunodominance in antiviral immune response

Mats Bemark 

Johan Bengtsson-Palme
Interactions in the microbiome

Tomas Bergström

George Birchenough
Goblet cell-mediated mucosal defence

Susanna Cardell
Regulation of autoimmunity and tumor immunity

Carl-Fredrik Flach
The role of wastewater environments for development and surveillance of antibiotic resistance

Huamei Forsman
G protein-coupled receptor function and anti-inflammatory drug development

Vanda Friman

Magnus Gisslén

Anna Grahn
Neurological complications caused by varicella-zostervirus and enterovirus

Ali Harandi
Understanding the mechanisms of action of human vaccines

Kristoffer Hellstrand
Cell-mediated immunity in leukemia

Jan Holgersson
Glycan engineering of cells and proteins

Jan Holmgren

Gunnar Jacobsson
Clostridioides Difficile

Michael Kann
Intracellular transport of viral structures

Roger  Karlsson
Direct identification of disease-causing microorganisms in clinical samples using genomics and proteomics

Martin Lagging
Translational research on Tick-borne Encephalitis (TBE) and other flavivirus infections

Göran Larson
Glycans as mediators of infection and inflammation

Joakim Larsson
Environmental dimension of antibiotic resistance

Jan-Åke Liljeqvist
Development of a vaccine against herpes simplex virus 2 infection

Per Lindahl
Pro-oxidant cancer therapies

Sara Lindén 
Mucins in infection and cancer

Anna Lundgren

Inger Mattsby-Baltzer
Antimicrobial peptides and proteins in humans

Edward Moore
Studies on microbial diversity: characterisation, classification and identification of clinically-relevant microorganisms

Peter Norberg
Viral evolution and genetics

Helene Norder

Thomas Nyström
Cellular aging and protein quality control

Lars Olaison

Ruth Palmer
Investigating the ALK receptor tyrosine kinase in development and disease

Thaher Pelaseyed
Membrane mucins in mucosal innate immunity

Marianne Quiding-Järbrink
T cell immunity in intestinal tumors

Sukanya Raghavan 
Identification of biomarkers of clinical response to PD-1 blockade in lung cancer patients

Susann Skovbjerg 
Pneumococci and related infections globally and in Sweden

Marie Studahl
Viral infections of the central nervous system

Ann-Mari Svennerholm

Annetta Svitorka Härtlova
Molecular mechanisms of innate immune signalling

Ka-Wei Tang
Ka-Wei Tang group

Susann Teneberg
Glycosphingolipids in infection and immunity

Åsa Torinsson Naluai
Mapping inflammation and metabolism in chronic disease

Anna von Mentzer
Microbial genomics meets functional microbiology

Rune Wejståhl
Antiviral treatment of chronic hepatitis C and the effect on quality of life, cognitive function and cerebrospinal fluid markers of neuronal injury and inflammation.

Christine Wennerås
The Neoehrlichia Eosinophil (NEOs) Project

Johan Westin

Mary Jo Wick
The role of intestinal mononuclear phagocytes in driving the chronic inflammation of inflammatory bowel disease

Agnes Wold

Ulf Yrlid
Improvements of immune responses against colorectal cancers and enterotoxins

Christina Åhrén
Improved therapeutical guidelines and surveillance of multi-resistant gut bacteria with ESBL

Lena Öhman
Gut microbiota, immune profile and the link to gastrointestinal diseases

Frida Abel 
Genomic studies of neural tumors

Levent Akyürek
Clinical lung cancer research and biology of filamins

Mattias Andersson
Research on the MYB oncogene in acute leukemias

Fredrik Bergh Thorén
NK cells in inflammation and cancer

Johan Botling
Precision diagnostics and tumor immunology in lung cancer

Susanna Cardell
Regulation of autoimmunity and tumor immunity

Helena Carén
Brain cancer stem cells and tumour epigenetics

Linda Fogelstrand
Measurable residual disease in acute myeloid leukemia 

Carolina Guibentif
Mammalian developmental hematopoiesis and leukemia

Claes Gustafsson
Mitochondrial gene expression

Bengt Hallberg
The function and importance of ALK TRK in development and disease

Ola Hammarsten

Kristoffer Hellstrand
Cell-mediated immunity in leukemia

Pekka Jaako
Protein synthesis control in hematopoiesis and leukemia

Martin Johansson
Martin Johansson group

Meena Kanduri
Epigenetics of chronic lymphocytic leukemia

Göran Landberg
Göran Landberg group

Erik Larsson Lekholm 
Human genomics and bioinformatics group

Anders Lindahl

Per Lindahl
Pro-oxidant cancer therapies

Sara Lindén 
Mucins in infection and cancer

Tommy Martinsson

Anna Martner
Anna Martner group

Tanmoy Mondal
Model MYCN mediated oncogenesis in Neuroblastoma using human trunk neural crest cells: transcriptomics and epigenomics based approaches

Noora Neittaanmäki
Novel imaging technologies and artificial intelligence in digital pathology for improved cancer diagnostics

Mikael Nilsson
Mechanisms and pathogenesis of thyroid cancer

Ruth Palmer
Investigating the ALK receptor tyrosine kinase in development and disease

Lars Palmqvist
Molecular mechanisms in the development of acute myeloid leukemia

Marianne Quiding-Järbrink
T cell immunity in intestinal tumors

Stina Simonsson

Göran Stenman  
Göran Stenman group

Anders Ståhlberg
Anders Ståhlberg group

Ka-Wei Tang
Ka-Wei Tang group

Ulf Yrlid
Improvements of immune responses against colorectal cancers and enterotoxins

Pierre Åman
Pierre Åman group

Fredrik Bergh Thorén
Fredrik Bergh Thorén group

George Birchenough
Goblet cell-mediated mucosal defence

Joan Camuñas
Data-driven biomedicine and precision medicine

Maria Falkenberg
Molecular mechanisms of DNA replication in human mitochondria

Huamei Forsman
G protein-coupled receptor function and anti-inflammatory drug development

Claes Gustafsson
Mitochondrial gene expression

Bengt Hallberg
The function and importance of ALK TRK in development and disease

Gunnar Hansson
Mucus and mucins in the gastrointestinal and respiratory tracts

Pekka Jaako
Protein synthesis control in hematopoiesis and leukemia

Eva Jennische

Malin Johansson
Studies of different goblet cells and proteins involved in mucus protection of the intestinal epithelium

Linda Johansson
Structure-function of transmembrane protein complexes

Chandrasekhar Kanduri
Noncoding RNA in Development and Disease

Michael Kann
Intracellular transport of viral structures

Roger  Karlsson
Direct identification of disease-causing microorganisms in clinical samples using genomics and proteomics

Göran Larson
Glycans as mediators of infection and inflammation

Erik Larsson Lekholm 
Human genomics and bioinformatics group

Per Lindahl
Pro-oxidant cancer therapies

Sara Lindén 
Mucins in infection and cancer

Ana Luis
Microbiota-mucin interactions in the human gut

Anna Martner
Anna Martner group

Tanmoy Mondal
Model MYCN mediated oncogenesis in Neuroblastoma using human trunk neural crest cells: transcriptomics and epigenomics based approaches

Thomas Nyström
Cellular aging and protein quality control

Ruth Palmer
Investigating the ALK receptor tyrosine kinase in development and disease

Ingela Parmryd
The Interplay between Lipid Nanodomains, Protein Clusters and Cell Topography in Cell Signalling

Thaher Pelaseyed
Membrane mucins in mucosal innate immunity

Aishe Sarshad
Noncoding small RNAs in health and disease 

Fredrik Sterky
Fredrik Sterky Group

Annetta Svitorka Härtlova
Anetta S. Härtlova group

Susann Teneberg
Glycosphingolipids in infection and immunity

Anne Uv
Epithelial tube morphogenesis

Anna von Mentzer
Microbial genomics meets functional microbiology