Key Research Areas
Key Areas within the research at the Institute of Biomedicine
The Institute of Biomedicine has a departmental structure consisting of four departments, which creates a critical mass necessary for nationally leading, and internationally competitive research. This structure largely mirrors that of the division of clinical units at Sahlgrenska University Hospital (SU, separate entity from GU), which is one of our largest partners. The close collaboration with SU, which is part of the Västra Götaland region, a county bringing together large parts of Western Sweden, means that our research becomes both nationally and internationally visible and easily applicable. In addition to our advanced translational research, we conduct basic molecular and microbiological, biochemical and medical research at a high international level with many worldwide research collaborations.
In our drive to be nationally leading and internationally competitive, we focus on strategies that will develop research environments that suit our defined research areas. The Department of Biomedicine has four main key areas.
1. Infection and immunology
2. Cancer and stem cell biology
3. Genetics and molecular medicine
4. Cell and molecular biology, including glycobiology
Research groups in key areas
Davide Angeletti
B cell and antibody immunodominance in antiviral immune response
Johan Bengtsson-Palme
Interactions in the microbiome
George Birchenough
Goblet cell-mediated mucosal defence
Susanna Cardell
Regulation of autoimmunity and tumor immunity
Carl-Fredrik Flach
The role of wastewater environments for development and surveillance of antibiotic resistance
Huamei Forsman
G protein-coupled receptor function and anti-inflammatory drug development
Ali Harandi
Understanding the mechanisms of action of human vaccines
Kristoffer Hellstrand
Cell-mediated immunity in leukemia
Jan Holgersson
Glycan engineering of cells and proteins
Gunnar Jacobsson
Clostridioides Difficile
Michael Kann
Intracellular transport of viral structures
Martin Lagging
Translational research on Tick-borne Encephalitis (TBE) and other flavivirus infections
Göran Larson
Glycans as mediators of infection and inflammation
Joakim Larsson
Environmental dimension of antibiotic resistance
Jan-Åke Liljeqvist
Development of a vaccine against herpes simplex virus 2 infection
Per Lindahl
Pro-oxidant cancer therapies
Sara Lindén
Mucins in infection and cancer
Inger Mattsby-Baltzer
Antimicrobial peptides and proteins in humans
Peter Norberg
Viral evolution and genetics
Thomas Nyström
Cellular aging and protein quality control
Thaher Pelaseyed
Membrane mucins in mucosal innate immunity
Marianne Quiding-Järbrink
T cell immunity in intestinal tumors
Sukanya Raghavan
Identification of biomarkers of clinical response to PD-1 blockade in lung cancer patients
Susann Skovbjerg
Pneumococci and related infections globally and in Sweden
Marie Studahl
Viral infections of the central nervous system
Annetta Svitorka Härtlova
Molecular mechanisms of innate immune signalling
Ka-Wei Tang
Ka-Wei Tang group
Susann Teneberg
Glycosphingolipids in infection and immunity
Åsa Torinsson Naluai
Mapping inflammation and metabolism in chronic disease
Anna von Mentzer
Microbial genomics meets functional microbiology
Christine Wennerås
The Neoehrlichia Eosinophil (NEOs) Project
Ulf Yrlid
Improvements of immune responses against colorectal cancers and enterotoxins
Christina Åhrén
Improved therapeutical guidelines and surveillance of multi-resistant gut bacteria with ESBL
Lena Öhman
Gut microbiota, immune profile and the link to gastrointestinal diseases
Frida Abel
Genomic studies of neural tumors
Levent Akyürek
Clinical lung cancer research and biology of filamins
Mattias Andersson
Research on the MYB oncogene in acute leukemias
Fredrik Bergh Thorén
NK cells in inflammation and cancer
Susanna Cardell
Regulation of autoimmunity and tumor immunity
Helena Carén
Brain cancer stem cells and tumour epigenetics
Linda Fogelstrand
Measurable residual disease in acute myeloid leukemia
Carolina Guibentif
Mammalian developmental hematopoiesis and leukemia
Claes Gustafsson
Mitochondrial gene expression
Bengt Hallberg
The function and importance of ALK TRK in development and disease
Kristoffer Hellstrand
Cell-mediated immunity in leukemia
Pekka Jaako
Protein synthesis control in hematopoiesis and leukemia
Martin Johansson
Martin Johansson group
Meena Kanduri
Epigenetics of chronic lymphocytic leukemia
Göran Landberg
Göran Landberg group
Erik Larsson Lekholm
Human genomics and bioinformatics group
Per Lindahl
Pro-oxidant cancer therapies
Sara Lindén
Mucins in infection and cancer
Anna Martner
Anna Martner group
Noora Neittaanmäki
Novel imaging technologies and artificial intelligence in digital pathology for improved cancer diagnostics
Mikael Nilsson
Mechanisms and pathogenesis of thyroid cancer
Lars Palmqvist
Molecular mechanisms in the development of acute myeloid leukemia
Marianne Quiding-Järbrink
T cell immunity in intestinal tumors
Göran Stenman
Göran Stenman group
Anders Ståhlberg
Anders Ståhlberg group
Ka-Wei Tang
Ka-Wei Tang group
Ulf Yrlid
Improvements of immune responses against colorectal cancers and enterotoxins
Pierre Åman
Pierre Åman group
Frida Abel
Genomic studies of neural tumors
Magnus Braide
Peritoneal dialysis and peritoneal reactions to biomaterials
Joan Camuñas
Data-driven biomedicine and precision medicine
Sven Enerbäck
Transcriptional regulation of metabolic pathways
Maria Falkenberg
Molecular mechanisms of DNA replication in human mitochondria
Linda Fogelstrand
Measurable residual disease in acute myeloid leukemia
Gunnar Hansson
Mucus and mucins in the gastrointestinal and respiratory tracts
Christina Jern
On the hemostatic and inflammatory pathways in ischemic stroke: an integrated clinical and experimental study
Martin Johansson
Martin Johansson group
Linda Johansson
Structure-function of transmembrane protein complexes
Chandrasekhar Kanduri
Noncoding RNA in Development and Disease
Ola Nilsson Wassen
Ola Nilsson group
Anders Oldfors
Neuromuscular disorders
Kjell Olmarker
Disc herniation and sciatica - Improved diagnostics and innovative medical treatments
Martin Ott
Mitochondrial Biogenesis
Lars Palmqvist
Molecular mechanisms in the development of acute myeloid leukemia
Fredrik Sterky
Mechanisms of synapse formation and neurodevelopmental diseases
Åsa Torinsson Naluai
Mapping inflammation and metabolism in chronic disease
Fredrik Bergh Thorén
Fredrik Bergh Thorén group
George Birchenough
Goblet cell-mediated mucosal defence
Joan Camuñas
Data-driven biomedicine and precision medicine
Maria Falkenberg
Molecular mechanisms of DNA replication in human mitochondria
Huamei Forsman
G protein-coupled receptor function and anti-inflammatory drug development
Claes Gustafsson
Mitochondrial gene expression
Bengt Hallberg
The function and importance of ALK TRK in development and disease
Gunnar Hansson
Mucus and mucins in the gastrointestinal and respiratory tracts
Pekka Jaako
Protein synthesis control in hematopoiesis and leukemia
Malin Johansson
Studies of different goblet cells and proteins involved in mucus protection of the intestinal epithelium
Linda Johansson
Structure-function of transmembrane protein complexes
Chandrasekhar Kanduri
Noncoding RNA in Development and Disease
Michael Kann
Intracellular transport of viral structures
Göran Larson
Glycans as mediators of infection and inflammation
Erik Larsson Lekholm
Human genomics and bioinformatics group
Per Lindahl
Pro-oxidant cancer therapies
Sara Lindén
Mucins in infection and cancer
Anna Luis
Microbiota-mucin interactions in the human gut
Anna Martner
Anna Martner group
Thomas Nyström
Cellular aging and protein quality control
Ingela Parmryd
The Interplay between Lipid Nanodomains, Protein Clusters and Cell Topography in Cell Signalling
Thaher Pelaseyed
Membrane mucins in mucosal innate immunity
Aishe Sarshad
Noncoding small RNAs in health and disease
Fredrik Sterky
Fredrik Sterky Group
Annetta Svitorka Härtlova
Anetta S. Härtlova group
Susann Teneberg
Glycosphingolipids in infection and immunity
Anne Uv
Epithelial tube morphogenesis
Anna von Mentzer
Microbial genomics meets functional microbiology