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Mattias Lorentzon
Professor/ Chief Physician
Department of Internal Medicine and Clinical NutritionAbout Mattias Lorentzon
About Mattias Lorentzon
Mattias Lorentzon is a professor of geriatric medicine at the Institute of Medicine, University of Gothenburg, and serves as Chief Physician at the Osteoporosis Clinic at Sahlgrenska University Hospital in Mölndal. He is the founder and leader of the Fracture Liaison Service at Sahlgrenska University Hospital in Gothenburg. Currently, he heads the Clinical Osteoporosis Research Group at the Sahlgrenska Osteoporosis Centre, University of Gothenburg. Lorentzon acts as an expert reviewer for various international organizations and holds positions on the Scientific Advisory Council of the International Society for Clinical Densitometry and the Committee of Scientific Advisors for the International Osteoporosis Foundation.
He has received multiple international research accolades, including the 2024 European Calcified Tissue Society (ECTS) Steven Boonen Clinical Research Award. During his tenure as President of the Swedish Osteoporosis Society (2011-2015) and as an expert reviewer shaping diagnosis and treatment guidelines for the National Board of Health and Welfare (Socialstyrelsen), he significantly influenced the advancement of osteoporosis evaluation and treatment standards in Sweden. Lorentzon is a frequently sought-after reviewer for various scientific journals, such as NEJM, JBMR, JCEM, Osteoporosis International, and Annals of Internal Medicine. Additionally, he serves as a member of the editorial board of Osteoporosis International.
Research Interests and Publications
Lorentzon's primary research interests encompass osteoporosis and fracture epidemiology, fracture risk prediction, innovative assessments of bone strength, and the impact of gut microbiota on bone health. He has led and completed numerous Randomized Controlled Trials (RCTs) examining the effects of probiotic supplements. As the principal investigator of the large prospective SUPERB cohort study in Sweden, he aims to identify novel factors for osteoporosis and fracture prediction in elderly women. Lorentzon has made a substantial contribution in the testing of clinical efficacy of the highly effective and recently approved osteoporosis drug, romosozumab, as the principal investigator in Sweden. He currently leads several intervention studies in Gothenburg and Melbourne, exploring the effects of both 1st and 2nd generation probiotics on bone health. Lorentzon is an active member of the FRAX research team, a leading international osteoporosis epidemiology group focused on developing fracture prediction models.
His substantial contributions to osteoporosis research are reflected in over 320 peer-reviewed publications, including significant works in prestigious journals such as NEJM, JAMA, Nature, Nature Genetics, and The Lancet, garnering over 39,000 citations as of October 2024.
Selected publications
· Type 2 Diabetes and Fracture Risk in Older Women. Zoulakis M, Johansson L, Litsne H, Axelsson K, Lorentzon M. JAMA Netw Open. 2024 Aug 1;7(8):e2425106.
· Limosilactobacillus reuteri 6475 and Prevention of Early Postmenopausal Bone Loss: A Randomized Clinical Trial. Gregori G, Pivodic A, Magnusson P, Johansson L, Hjertonsson U, Brättemark E, Lorentzon M. JAMA Netw Open. 2024 Jun 3;7(6):e2415455.
· Khan MT, Dwibedi C, Sundh D, Pradhan M, Kraft JD, Caesar R, Tremaroli V*, Lorentzon M*, Bäckhed F*. Synergy and oxygen adaptation for development of next-generation probiotics. Nature. 2023 Aug;620(7973):381-385. doi: 10.1038/s41586-023-06378-w. *These authors jointly supervised this work.
· Risk of fracture in adults with type 2 diabetes in Sweden: A national cohort study. Axelsson KF, Litsne H, Kousoula K, Franzen S, Eliasson B, Lorentzon M. PLoS Med 2023;20(1):e1004172. DOI: 10.1371/journal.pmed.1004172.
· Analysis of Comorbidities, Clinical Outcomes, and Parathyroidectomy in Adults With Primary Hyperparathyroidism. Axelsson KF, Wallander M, Johansson H, Harvey NC, Vandenput L, McCloskey E, Liu E, Kanis JA, Litsne H, Lorentzon M. JAMA Netw Open. 2022 Jun 1;5(6):e2215396. doi: 10.1001/jamanetworkopen. 2022.15396.
· Association Between Recurrent Fracture Risk and Implementation of Fracture Liaison Services in four Swedish hospitals A Cohort Study. Axelsson KF, Johansson H, Lundh D, Möller M, Lorentzon M. J Bone Miner Res. 2020 Feb 25. doi: 10.1002/jbmr.3990
· Grade 1 Vertebral Fractures Identified by Densitometric Lateral Spine Imaging Predict Incident Major Osteoporotic Fracture Independently of Clinical Risk Factors and Bone Mineral Density in Older Women. Johansson L, Sundh D, Magnusson P, Rukmangatharajan K, Mellström D, Nilsson AG, Lorentzon M. J Bone Miner Res. 2020 Jun 15. doi: 10.1002/jbmr.4108
· Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis. Saag KG, Petersen J, Brandi ML, Karaplis AC, Lorentzon M, Thomas T, Maddox J, Fan M, Meisner PD, Grauer A. N Engl J Med. 2017 Sep 11. doi: 10.1056/NEJMoa1708322.
· Lactobacillus reuteri reduces bone loss in older women with low bone mineral density - a randomized, placebo-controlled, double-blind, clinical trial. Nilsson AG, Sundh D, Bäckhed F, Lorentzon M. J Intern Med. 2018 Jun 21. doi: 10.1111/joim.12805.
· Association Between Alendronate Use and Hip Fracture Risk in Older Patients Using Oral Prednisolone. Axelsson KF, Nilsson AG, Wedel H, Lundh D, Lorentzon M. JAMA. 2017 Jul 11;318(2):146-155. doi: 10.1001/jama.2017.8040.
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Bone Marrow Adiposity Assessed by HRpQCT Is Related to Fracture Risk and Bone Mineral Density in Older Swedish
Women
Michail Zoulakis, Kristian F Axelsson, Henrik Litsne, Lisa Johansson, Mattias Lorentzon
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM - 2025 -
Association between walking and hip fracture in women aged 65 and older: 20-year follow-up from the study of osteoporotic
fractures
Enwu Liu, Ryan Yan Liu, John Moraros, Eugene V. McCloskey, Nicholas C. Harvey, Mattias Lorentzon, Helena Johansson, John A. Kanis
OSTEOPOROSIS INTERNATIONAL - 2025 -
Circulating Baseline CXCR3+Th2 and Th17 Cell Proportions Correlate With Trabecular Bone Loss After 48 Weeks of Biological Treatment in Early Rheumatoid
Arthritis
Julia Scheffler, Christina Drevinge, Catharina Lindholm, Inger Gjertsson, Kristina Lend, Merete Lund Hetland, Mikkel Ostergaard, Till Uhlig, Marte Schrumpf Heiberg, Espen A. Haavardsholm, Michael T. Nurmohamed, Jon Lampa, Tuulikki Sokka-Isler, Dan Nordstrom, Kim Horslev-Petersen, Bjorn Gudbjornsson, Gerdur Grondal, Ronald van Vollenhoven, Hans Carlsten, Mattias Lorentzon, Anna-Karin Hultgård Ekwall, Anna Rudin, Ulrika Islander
ACR OPEN RHEUMATOLOGY - 2025 -
Rheumatoid arthritis and subsequent fracture risk: an individual person meta-analysis to update
FRAX.
John A Kanis, Helena Johansson, Eugene V McCloskey, Enwu Liu, Marian Schini, Liesbeth Vandenput, Kristina E Åkesson, Fred A Anderson, Rafael Azagra, Cecilie L Bager, Charlotte Beaudart, Heike A Bischoff-Ferrari, Emmanuel Biver, Olivier Bruyère, Jane A Cauley, Jacqueline R Center, Roland Chapurlat, Claus Christiansen, Cyrus Cooper, Carolyn J Crandall, Steven R Cummings, José A P da Silva, Bess Dawson-Hughes, Adolfo Diez-Perez, Alyssa B Dufour, John A Eisman, Petra J M Elders, Serge Ferrari, Yuki Fujita, Saeko Fujiwara, Claus-Christian Glüer, Inbal Goldshtein, David Goltzman, Vilmundur Gudnason, Jill Hall, Didier Hans, Mari Hoff, Rosemary J Hollick, Martijn Huisman, Masayuki Iki, Sophia Ish-Shalom, Graeme Jones, Magnus K Karlsson, Sundeep Khosla, Douglas P Kiel, Woon-Puay Koh, Fjorda Koromani, Mark A Kotowicz, Heikki Kröger, Timothy Kwok, Olivier Lamy, Arnulf Langhammer, Bagher Larijani, Kurt Lippuner, Fiona E A McGuigan, Dan Mellström, Thomas Merlijn, Tuan V Nguyen, Anna Nordström, Peter Nordström, Terence W O Neill, Barbara Obermayer-Pietsch, Claes Ohlsson, Eric S Orwoll, Julie A Pasco, Fernando Rivadeneira, Anne-Marie Schott, Eric J Shiroma, Kristin Siggeirsdottir, Eleanor M Simonsick, Elisabeth Sornay-Rendu, Reijo Sund, Karin Swart, Pawel Szulc, Junko Tamaki, David J Torgerson, Natasja M van Schoor, Tjeerd P van Staa, Joan Vila, Nicole C Wright, Noriko Yoshimura, M Carola Zillikens, Marta Zwart, Nicholas C Harvey, Mattias Lorentzon, William D Leslie
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 2025 -
Prediction of hip fracture by high-resolution peripheral quantitative computed tomography in older Swedish
women
Raju Jaiswal, Aldina Pivodic, Michail Zoulakis, Kristian F Axelsson, Henrik Litsne, Lisa Johansson, Mattias Lorentzon
JOURNAL OF BONE AND MINERAL RESEARCH - 2025 -
Evaluación del riesgo de fractura con FRAX y
FRAXplus
Teck H.A. Tan, Helena Johansson, Nicholas C. Harvey, Mattias Lorentzon, John A. Kanis, Eugene McCloskey, Marian Schini
Gaceta medica de Mexico - 2024 -
Short-term risk of fracture is increased by deficits in cortical and trabecular bone microarchitecture independent of DXA BMD and FRAX: Bone Microarchitecture International Consortium (BoMIC) prospective
cohorts.
Marine Sarfati, Roland Chapurlat, Alyssa B Dufour, Elisabeth Sornay-Rendu, Blandine Merle, Steven K Boyd, Danielle E Whittier, David A Hanley, David Goltzman, Pawel Szulc, Andy Kin On Wong, Eric Lespessailles, Sundeep Khosla, Serge Ferrari, Emmanuel Biver, Claes Ohlsson, Mattias Lorentzon, Dan Mellström, Maria Nethander, Elizabeth J Samelson, Douglas P Kiel, Marian T Hannan, Mary L Bouxsein
Journal of Bone and Mineral Research - 2024 -
Effects of Synbiotic Supplementation on Bone and Metabolic Health in Caucasian Postmenopausal Women: Rationale and Design of the OsteoPreP
Trial
Alisa Turbić, Liesbeth Vandenput, Anoohya Gandham, Mattias Lorentzon
Nutrients - 2024 -
Real-world effectiveness of osteoporosis screening in older Swedish women
(SUPERB)
Michail Zoulakis, Kristian F Axelsson, Henrik Litsne, Lisa Johansson, Mattias Lorentzon
Bone - 2024 -
Cost-effectiveness intervention thresholds for romosozumab and teriparatide in the treatment of osteoporosis in the
UK
Fredrik Borgstrom, Mattias Lorentzon, Helena Johansson, Nicholas C. Harvey, Eugene McCloskey, Damon Willems, Douglas Knutsson, John A. Kanis
OSTEOPOROSIS INTERNATIONAL - 2024 -
Assessment of fracture risk with FRAX and
FRAXplus
Andre T. H. Tan, Helena Johansson, Nicholas C. Harvey, Mattias Lorentzon, John A. Kanis, Eugene McCloskey, Marian Schini
GACETA MEDICA DE MEXICO - 2024 -
A surrogate FRAX model for
Nepal
H. Johansson, D. Pandey, Mattias Lorentzon, N. C. Harvey, E. V. McCloskey, J. A. Kanis
ARCHIVES OF OSTEOPOROSIS - 2024 -
High physical activity is associated with greater cortical bone size, better physical function, and with lower risk of incident fractures independently of clinical risk factors in older women from the SUPERB
study
Lisa Johansson, Henrik Litsne, Kristian F Axelsson, Mattias Lorentzon
JOURNAL OF BONE AND MINERAL RESEARCH - 2024 -
Race-specific FRAX models are evidence-based and support equitable care: a response to the ASBMR Task Force report on Clinical Algorithms for Fracture
Risk
John A. Kanis, Nicholas C. Harvey, Mattias Lorentzon, Enwu Liu, Marian Schini, Bo Abrahamsen, Jonathan D. Adachi, Majed Alokail, Fredrik Borgstrom, Olivier Bruyere, John J. Carey, Patricia Clark, Cyrus Cooper, Elizabeth M. Curtis, Elaine M. Dennison, Manuel Diaz-Curiel, Hans P. Dimai, Daniel Grigorie, Mickael Hiligsmann, Patricia Khashayar, Willem Lems, E. Michael Lewiecki, Roman S. Lorenc, Alexandra Papaioannou, Jean-Yves Reginster, Rene Rizzoli, Eric Shiroma, Stuart L. Silverman, Eleanor Simonsick, Manuel Sosa-Henriquez, Pawel Szulc, Kate A. Ward, Noriko Yoshimura, Helena Johansson, Liesbeth Vandenput, Eugene V. McCloskey
OSTEOPOROSIS INTERNATIONAL - 2024 -
Sarcopenia definitions and their association with injurious falls in older Swedish women from the Sahlgrenska University Hospital Prospective Evaluation of Risk of Bone fractures (SUPERB)
study
Anoohya Gandham, Giulia Gregori, Lisa Johansson, Berit A M Larsson, Helena Johansson, Nicholas C. Harvey, Liesbeth Vandenput, Eugene McCloskey, John A. Kanis, Henrik Litsne, Kristian F Axelsson, Mattias Lorentzon
OSTEOPOROSIS INTERNATIONAL - 2024 -
Type 2 Diabetes and Fracture Risk in Older
Women
Michail Zoulakis, Lisa Johansson, Henrik Litsne, Kristian F Axelsson, Mattias Lorentzon
JAMA NETWORK OPEN - 2024 -
The role of different physical function tests for the prediction of fracture risk in older
women
Giulia Gregori, Lisa Johansson, Kristian F Axelsson, Raju Jaiswal, Henrik Litsne, Berit A M Larsson, Mattias Lorentzon
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE - 2024 -
Sarcopenia definitions and their association with fracture risk in older Swedish
women
Anoohya Gandham, Giulia Gregori, Lisa Johansson, Helena Johansson, Nicholas C. Harvey, Liesbeth Vandenput, Eugene McCloskey, John A. Kanis, Henrik Litsne, Kristian F Axelsson, Mattias Lorentzon
JOURNAL OF BONE AND MINERAL RESEARCH - 2024 -
Higher serum free thyroxine levels are associated with increased risk of hip fractures in older
men.
Johan Svensson, Claes Ohlsson, Magnus K Karlsson, Hans Herlitz, Mattias Lorentzon, Catharina Lewerin, Dan Mellström
Journal of Bone and Mineral Research - 2024 -
The significance of recent fracture location for imminent risk of hip and vertebral fractures-a nationwide cohort study on older adults in
Sweden
Mattias Lorentzon, Henrik Litsne, Kristian F Axelsson
OSTEOPOROSIS INTERNATIONAL - 2024 -
A meta-analysis of previous falls and subsequent fracture risk in cohort
studies.
Liesbeth Vandenput, Helena Johansson, Eugene V McCloskey, Enwu Liu, Marian Schini, Kristina E Åkesson, Fred A Anderson, Rafael Azagra, Cecilie L Bager, Charlotte Beaudart, Heike A Bischoff-Ferrari, Emmanuel Biver, Olivier Bruyère, Jane A Cauley, Jacqueline R Center, Roland Chapurlat, Claus Christiansen, Cyrus Cooper, Carolyn J Crandall, Steven R Cummings, José A P da Silva, Bess Dawson-Hughes, Adolfo Diez-Perez, Alyssa B Dufour, John A Eisman, Petra J M Elders, Serge Ferrari, Yuki Fujita, Saeko Fujiwara, Claus-Christian Glüer, Inbal Goldshtein, David Goltzman, Vilmundur Gudnason, Jill Hall, Didier Hans, Mari Hoff, Rosemary J Hollick, Martijn Huisman, Masayuki Iki, Sophia Ish-Shalom, Graeme Jones, Magnus K Karlsson, Sundeep Khosla, Douglas P Kiel, Woon-Puay Koh, Fjorda Koromani, Mark A Kotowicz, Heikki Kröger, Timothy Kwok, Olivier Lamy, Arnulf Langhammer, Bagher Larijani, Kurt Lippuner, Fiona E A McGuigan, Dan Mellström, Thomas Merlijn, Tuan V Nguyen, Anna Nordström, Peter Nordström, Terence W O'Neill, Barbara Obermayer-Pietsch, Claes Ohlsson, Eric S Orwoll, Julie A Pasco, Fernando Rivadeneira, Anne-Marie Schott, Eric J Shiroma, Kristin Siggeirsdottir, Eleanor M Simonsick, Elisabeth Sornay-Rendu, Reijo Sund, Karin M A Swart, Pawel Szulc, Junko Tamaki, David J Torgerson, Natasja M van Schoor, Tjeerd P van Staa, Joan Vila, Nicholas J Wareham, Nicole C Wright, Noriko Yoshimura, MCarola Zillikens, Marta Zwart, Nicholas C Harvey, Mattias Lorentzon, William D Leslie, John A Kanis
Osteoporosis International - 2024 -
Limosilactobacillus reuteri 6475 and Prevention of Early Postmenopausal Bone Loss: A Randomized Clinical
Trial
Giulia Gregori, Aldina Pivodic, Per Magnusson, Lisa Johansson, Ulrika Hjertonsson, Emma Brättemark, Mattias Lorentzon
JAMA NETWORK OPEN - 2024 -
Low Circulating Valine Associate With High Risk of Hip
Fractures
Louise Grahnemo, Anna L Eriksson, Maria Nethander, R. Johansson, Mattias Lorentzon, Dan Mellström, U. Pettersson-Kymmer, Claes Ohlsson
Journal of Clinical Endocrinology & Metabolism - 2023 -
Hemoglobin Levels Improve Fracture Risk Prediction in Addition to FRAX Clinical Risk Factors and Bone Mineral
Density
Raju Jaiswal, Helena Johansson, Kristian F Axelsson, Per Magnusson, Nicholas C. Harvey, Liesbeth Vandenput, Eugene McCloskey, John A. Kanis, Henrik Litsne, Lisa Johansson, Mattias Lorentzon
The Journal of clinical endocrinology and metabolism - 2023 -
Comparison of Fractures Among Older Adults Who Are Ambulatory vs Those Who Use Wheelchairs in
Sweden
Kristian F Axelsson, Henrik Litsne, Mattias Lorentzon
JAMA NETWORK OPEN - 2023 -
Adjusting conventional FRAX estimates of fracture probability according to the number of prior falls in the preceding
year
J. A. Kanis, H. Johansson, N. C. Harvey, Mattias Lorentzon, E. W. Liu, Liesbeth Vandenput, S. Morin, W. D. Leslie, E. V. McCloskey
Osteoporosis International - 2023 -
Adjusting FRAX Estimates of Fracture Probability Based on a Positive Vertebral Fracture
Assessment
C. R. Ye, W. D. Leslie, S. N. Morin, L. M. Lix, E. V. McCloskey, H. Johansson, N. C. Harvey, Mattias Lorentzon, J. A. Kanis
JAMA Network Open - 2023 -
Synergy and oxygen adaptation for development of next-generation
probiotics
Muhammad Tanweer Khan, Chinmay Dwibedi, Daniel Sundh, Meenakshi Pradhan, Jamie D. Kraft, Robert Caesar, Valentina Tremaroli, Mattias Lorentzon, Fredrik Bäckhed
Nature - 2023 -
The Importance of Recent Prevalent Fracture Site for Imminent Risk of Fracture - A Retrospective, Nationwide Cohort Study of Older Swedish Men and
Women
Kristian F Axelsson, Henrik Litsne, Mattias Lorentzon
Journal of Bone and Mineral Research - 2023 -
Genetic insights into resting heart rate and its role in cardiovascular
disease.
Yordi J van de Vegte, Ruben N Eppinga, M Yldau van der Ende, Yanick P Hagemeijer, Yuvaraj Mahendran, Elias Salfati, Albert V Smith, Vanessa Y Tan, Dan E Arking, Ioanna Ntalla, Emil V Appel, Claudia Schurmann, Jennifer A Brody, Rico Rueedi, Ozren Polasek, Gardar Sveinbjornsson, Cecile Lecoeur, Claes Ladenvall, Jing Hua Zhao, Aaron Isaacs, Lihua Wang, Jian'an Luan, Shih-Jen Hwang, Nina Mononen, Kirsi Auro, Anne U Jackson, Lawrence F Bielak, Linyao Zeng, Nabi Shah, Maria Nethander, Archie Campbell, Tuomo Rankinen, Sonali Pechlivanis, Lu Qi, Wei Zhao, Federica Rizzi, Toshiko Tanaka, Antonietta Robino, Massimiliano Cocca, Leslie Lange, Martina Müller-Nurasyid, Carolina Roselli, Weihua Zhang, Marcus E Kleber, Xiuqing Guo, Henry J Lin, Francesca Pavani, Tessel E Galesloot, Raymond Noordam, Yuri Milaneschi, Katharina E Schraut, Marcel den Hoed, Frauke Degenhardt, Stella Trompet, Marten E van den Berg, Giorgio Pistis, Yih-Chung Tham, Stefan Weiss, Xueling S Sim, Hengtong L Li, Peter J van der Most, Ilja M Nolte, Leo-Pekka Lyytikäinen, M Abdullah Said, Daniel R Witte, Carlos Iribarren, Lenore Launer, Susan M Ring, Paul S de Vries, Peter Sever, Allan Linneberg, Erwin P Bottinger, Sandosh Padmanabhan, Bruce M Psaty, Nona Sotoodehnia, Ivana Kolcic, David O Arnar, Daniel F Gudbjartsson, Hilma Holm, Beverley Balkau, Claudia T Silva, Christopher H Newton-Cheh, Kjell Nikus, Perttu Salo, Karen L Mohlke, Patricia A Peyser, Heribert Schunkert, Mattias Lorentzon, Jari Lahti, Dabeeru C Rao, Marilyn C Cornelis, Jessica D Faul, Jennifer A Smith, Katarzyna Stolarz-Skrzypek, Stefania Bandinelli, Maria Pina Concas, Gianfranco Sinagra, Thomas Meitinger, Melanie Waldenberger, Moritz F Sinner, Konstantin Strauch, Graciela E Delgado, Kent D Taylor, Jie Yao, Luisa Foco, Olle Melander, Jacqueline de Graaf, Renée de Mutsert, Eco J C de Geus, Åsa Johansson, Peter K Joshi, Lars Lind, Andre Franke, Peter W Macfarlane, Kirill V Tarasov, Nicholas Tan, Stephan B Felix, E-Shyong Tai, Debra Q Quek, Harold Snieder, Johan Ormel, Martin Ingelsson, Cecilia Lindgren, Andrew P Morris, Olli T Raitakari, Torben Hansen, Themistocles Assimes, Vilmundur Gudnason, Nicholas J Timpson, Alanna C Morrison, Patricia B Munroe, David P Strachan, Niels Grarup, Ruth J F Loos, Susan R Heckbert, Peter Vollenweider, Caroline Hayward, Kari Stefansson, Philippe Froguel, Leif Groop, Nicholas J Wareham, Cornelia M van Duijn, Mary F Feitosa, Christopher J O'Donnell, Mika Kähönen, Markus Perola, Michael Boehnke, Sharon L R Kardia, Jeanette Erdmann, Colin N A Palmer, Claes Ohlsson, David J Porteous, Johan G Eriksson, Claude Bouchard, Susanne Moebus, Peter Kraft, David R Weir, Daniele Cusi, Luigi Ferrucci, Sheila Ulivi, Giorgia Girotto, Adolfo Correa, Stefan Kääb, Annette Peters, John C Chambers, Jaspal S Kooner, Winfried März, Jerome I Rotter, Andrew A Hicks, J. Gustav Smith, Lambertus A L M Kiemeney, Dennis O Mook-Kanamori, Brenda W J H Penninx, Ulf Gyllensten, James F Wilson, Stephen Burgess, Johan Sundström, Wolfgang Lieb, J Wouter Jukema, Mark Eijgelsheim, Edward L M Lakatta, Ching-Yu Cheng, Marcus Dörr, Tien-Yin Wong, Charumathi Sabanayagam, Albertine J Oldehinkel, Harriette Riese, Terho Lehtimäki, Niek Verweij, Pim van der Harst
Nature communications - 2023 -
Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome-Wide Association Meta-Analysis Followed by Mendelian
Randomization.
Jie Zheng, Eleanor Wheeler, Maik Pietzner, Till F M Andlauer, Michelle S Yau, April E Hartley, Ben Michael Brumpton, Humaira Rasheed, John P Kemp, Monika Frysz, Jamie Robinson, Sjur Reppe, Vid Prijatelj, Kaare M Gautvik, Louise Falk, Winfried Maerz, Ingrid Gergei, Patricia A Peyser, Maryam Kavousi, Paul S de Vries, Clint L Miller, Maxime Bos, Sander W van der Laan, Rajeev Malhotra, Markus Herrmann, Hubert Scharnagl, Marcus Kleber, George Dedoussis, Eleftheria Zeggini, Maria Nethander, Claes Ohlsson, Mattias Lorentzon, Nick Wareham, Claudia Langenberg, Michael V Holmes, George Davey Smith, Jonathan H Tobias
Arthritis & rheumatology (Hoboken, N.J.) - 2023 -
An assessment of intervention thresholds for high fracture risk in
Chile
E. L. Gavilanez, I. N. Luis, N. G. Mario, Helena Johansson, N. C. Harvey, Mattias Lorentzon, E. Liu, Liesbeth Vandenput, E. V. McCloskey, J. A. Kanis
Archives of Osteoporosis - 2023 -
A new FRAX model for
Brazil
B. H. Albergaria, C. A.F. Zerbini, M. Lazaretti-Castro, S. R. Eis, T. Vilaca, H. Johansson, N. C. Harvey, E. Liu, L. Vandenput, Mattias Lorentzon, M. Schini, E. McCloskey, J. A. Kanis
Archives of Osteoporosis - 2023 -
Bone mineral density loci specific to the skull portray potential pleiotropic effects on
craniosynostosis
C. Medina-Gomez, B. H. Mullin, A. Chesi, V. Prijatelj, J. P. Kemp, C. Shochat-Carvalho, K. Trajanoska, C. Wang, R. Joro, T. E. Evans, K. E. Schraut, R. Li-Gao, T. S. Ahluwalia, M. C. Zillikens, K. Zhu, D. O. Mook-Kanamori, D. S. Evans, Maria Nethander, M. J. Knol, G. Thorleifsson, I. Prokic, B. Zemel, L. Broer, F. E. McGuigan, N. M. van Schoor, S. Reppe, M. A. Pawlak, S. H. Ralston, N. van der Velde, Mattias Lorentzon, K. Stefansson, H. H. H. Adams, S. G. Wilson, M. A. Ikram, J. P. Walsh, T. A. Lakka, K. M. Gautvik, J. F. Wilson, E. S. Orwoll, C. M. van Duijn, K. Bonnelykke, A. G. Uitterlinden, U. Styrkarsdottir, K. E. Akesson, T. D. Spector, J. H. Tobias, Claes Ohlsson, J. F. Felix, H. Bisgaard, S. F. A. Grant, J. B. Richards, D. M. Evans, B. van der Eerden, J. van de Peppel, C. Ackert-Bicknell, D. Karasik, E. Kague, F. Rivadeneira
Communications Biology - 2023 -
Increased Bone Material Strength Index Is Positively Associated With the Risk of Incident Osteoporotic Fractures in Older Swedish
Women
Raju Jaiswal, Michail Zoulakis, Kristian F Axelsson, Anna Darelid, Robert Rudäng, Daniel Sundh, Henrik Litsne, Lisa Johansson, Mattias Lorentzon
Journal of Bone and Mineral Research - 2023 -
FRAX Adjustment by Trabecular Bone Score with or Without Bone Mineral Density: The Manitoba BMD
Registry
W. D. Leslie, N. Binkley, E. V. McCloskey, H. Johansson, N. C. Harvey, Mattias Lorentzon, J. A. Kanis, D. Hans
Journal of Clinical Densitometry - 2023 -
Occurrence and relative risks for non-vertebral fractures in patients with ankylosing spondylitis compared with the general population: a register-based study from
Sweden
Karin Bengtsson, J. Askling, Mattias Lorentzon, B. Rosengren, Anna Deminger, Eva Klingberg, Lennart T. H. Jacobsson, Helena Forsblad d'Elia
Rmd Open - 2023 -
Risk of fracture in adults with type 2 diabetes in Sweden: A national cohort
study
Kristian F Axelsson, Henrik Litsne, Konstantina Kousoula, Stefan Franzén, B. Eliasson, Mattias Lorentzon
Plos Medicine - 2023 -
Increased fracture risk in Parkinson's disease - An exploration of mechanisms and consequences for fracture prediction with
FRAX
M. Schini, P. Bhatia, H. Shreef, H. Johansson, N. C. Harvey, Mattias Lorentzon, J. A. Kanis, O. Bandmann, E. V. McCloskey
Bone - 2023 -
Primary hyperparathyroidism and fracture
probability
J. A. Kanis, N. C. Harvey, E. W. Liu, Liesbeth Vandenput, Mattias Lorentzon, E. V. McCloskey, R. Bouillon, B. Abrahamsen, L. Rejnmark, Helena Johansson
Osteoporosis International - 2023 -
Young Adult Male Patients With Childhood-onset IBD Have Increased Risks of Compromised Cortical and Trabecular Bone
Microstructures
Gudmundur Vignir Sigurdsson, S. Schmidt, Dan Mellström, Claes Ohlsson, Robert Saalman, Mattias Lorentzon
Inflammatory Bowel Diseases - 2023 -
Update of the fracture risk prediction tool FRAX: a systematic review of potential cohorts and analysis
plan
Liesbeth Vandenput, H. Johansson, E. V. McCloskey, E. Liu, K. E. Åkesson, F. A. Anderson, R. Azagra, C. L. Bager, C. Beaudart, H. A. Bischoff-Ferrari, E. Biver, O. Bruyère, J. A. Cauley, J. R. Center, R. Chapurlat, C. Christiansen, C. Cooper, C. J. Crandall, S. R. Cummings, J. A. P. da Silva, B. Dawson-Hughes, A. Diez-Perez, A. B. Dufour, J. A. Eisman, P. J. M. Elders, S. Ferrari, Y. Fujita, S. Fujiwara, C. C. Glüer, I. Goldshtein, D. Goltzman, V. Gudnason, J. Hall, D. Hans, M. Hoff, R. J. Hollick, M. Huisman, M. Iki, S. Ish-Shalom, G. Jones, M. K. Karlsson, S. Khosla, D. P. Kiel, W. P. Koh, F. Koromani, M. A. Kotowicz, H. Kröger, T. Kwok, O. Lamy, A. Langhammer, B. Larijani, K. Lippuner, Dan Mellström, T. Merlijn, A. Nordström, P. Nordström, T. W. O’Neill, B. Obermayer-Pietsch, Claes Ohlsson, E. S. Orwoll, J. A. Pasco, F. Rivadeneira, B. Schei, A. M. Schott, E. J. Shiroma, K. Siggeirsdottir, E. M. Simonsick, E. Sornay-Rendu, R. Sund, K. M. A. Swart, P. Szulc, J. Tamaki, D. J. Torgerson, N. M. van Schoor, T. P. van Staa, J. Vila, N. J. Wareham, N. C. Wright, N. Yoshimura, M. C. Zillikens, M. Zwart, N. C. Harvey, Mattias Lorentzon, W. D. Leslie, J. A. Kanis
Osteoporosis International - 2022 -
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease
prevention
Z. Wang, A. Emmerich, N. J. Pillon, T. Moore, D. Hemerich, M. C. Cornelis, E. Mazzaferro, S. Broos, T. S. Ahluwalia, T. M. Bartz, A. R. Bentley, L. F. Bielak, M. Chong, A. Y. Chu, D. Berry, R. Dorajoo, N. D. Dueker, E. Kasbohm, B. Feenstra, M. F. Feitosa, C. Gieger, M. Graff, L. M. Hall, T. Haller, F. P. Hartwig, D. A. Hillis, V. Huikari, N. Heard-Costa, C. Holzapfel, A. U. Jackson, A. Johansson, A. M. Jorgensen, M. A. Kaakinen, R. Karlsson, K. F. Kerr, B. Kim, C. M. Koolhaas, Z. Kutalik, V. Lagou, P. A. Lind, Mattias Lorentzon, L. P. Lyytikainen, M. Mangino, C. Metzendorf, K. R. Monroe, A. Pacolet, L. Perusse, R. Pool, R. C. Richmond, N. V. Rivera, S. Robiou-Du-Pont, K. E. Schraut, C. A. Schulz, H. M. Stringham, T. Tanaka, A. Teumer, C. Turman, P. J. Van der Most, M. Vanmunster, F. J. A. Van Rooij, J. V. Van Vliet-Ostaptchouk, X. S. Zhang, J. H. Zhao, W. Zhao, Z. Balkhiyarova, M. N. Balslev-Harder, S. E. Baumeister, J. Beilby, J. Blangero, D. I. Boomsma, S. Brage, P. S. Braund, J. A. Brody, M. Bruinenberg, U. Ekelund, C. T. Liu, J. W. Cole, F. S. Collins, L. A. Cupples, T. Esko, S. Enroth, J. D. Faul, L. Fernandez-Rhodes, A. E. Fohner, O. H. Franco, T. E. Galesloot, S. D. Gordon, N. Grarup, C. A. Hartman, G. Heiss, J. Hui, T. Illig, R. Jago, A. James, P. K. Joshi, T. Jung, M. Kahonen, T. O. Kilpelainen, W. P. Koh, I. Kolcic, P. P. Kraft, J. Kuusisto, L. J. Launer, A. H. Li, A. Linneberg, J. A. Luan, P. M. Vidal, S. E. Medland, Y. Milaneschi, A. Moscati, B. Musk, C. P. Nelson, I. M. Nolte, N. L. Pedersen, A. Peters, P. A. Peyser, C. Power, O. T. Raitakari, M. Reedik, A. P. Reiner, P. M. Ridker, I. Rudan, K. Ryan, M. A. Sarzynski, L. J. Scott, R. A. Scott, S. Sidney, K. Siggeirsdottir, A. V. Smith, J. A. Smith, E. Sonestedt, M. Strom, E. S. Tai, K. K. Teo, B. Thorand, A. Tonjes, A. Tremblay, A. G. Uitterlinden, J. Vangipurapu, N. Van Schoor, U. Volker, G. Willemsen, K. Williams, Q. Wong, H. C. Xu, K. L. Young, J. M. Yuan, M. C. Zillikens, A. B. Zonderman, A. Ameur, S. Bandinelli, J. C. Bis, M. Boehnke, C. Bouchard, D. I. Chasman, G. D. Smith, E. J. C. De Geus, L. Deldicque, M. Dorr, M. K. Evans, L. Ferrucci, M. Fornage, C. Fox, T. Garland, V. Gudnason, U. Gyllensten, T. Hansen, C. Hayward, B. L. Horta, E. Hypponen, M. R. Jarvelin, W. C. Johnson, S. L. R. Kardia, L. A. Kiemeney, M. Laakso, C. Langenberg, T. Lehtimaki, L. Le Marchand, P. K. E. Magnusson, N. G. Martin, M. Melbye, A. Metspalu, D. Meyre, K. E. North, Claes Ohlsson, A. J. Oldehinkel, M. Orho-Melander, G. Pare, T. Park, O. Pedersen, Bwjh Penninx, T. H. Pers, O. Polasek, I. Prokopenko, C. N. Rotimi, N. J. Samani, X. Sim, H. Snieder, T. I. A. Sorensen, T. D. Spector, N. J. Timpson, R. M. Van Dam, N. Van der Velde, C. M. Van Duijn, P. Vollenweider, H. Volzke, T. Voortman, G. Waeber, N. J. Wareham, D. R. Weir, H. E. Wichmann, J. F. Wilson, A. L. Hevener, A. Krook, J. R. Zierath, M. A. I. Thomis, R. J. F. Loos, M. Den Hoed
Nature Genetics - 2022 -
Anemia is associated with increased risk of non-vertebral osteoporotic fractures in elderly men: the MrOS Sweden
cohort
Hallgerdur Lind Kristjansdottir, Dan Mellström, Peter Johansson, M. Karlsson, Liesbeth Vandenput, Mattias Lorentzon, Hans Herlitz, Claes Ohlsson, Ulf H Lerner, Catharina Lewerin
Archives of Osteoporosis - 2022 -
The challenge of applying digital image processing software on intraoral radiographs for osteoporosis risk
assessment
J. Gullberg, A. Al-Okshi, D. H. Asan, A. Zainea, Daniel Sundh, Mattias Lorentzon, C. Lindh
Dentomaxillofacial Radiology - 2022 -
Analysis of Comorbidities, Clinical Outcomes, and Parathyroidectomy in Adults With Primary
Hyperparathyroidism
Kristian F Axelsson, Märit Wallander, Helena Johansson, N. C. Harvey, Liesbeth Vandenput, E. McCloskey, E. W. Liu, J. A. Kanis, Henrik Litsne, Mattias Lorentzon
Jama Network Open - 2022 -
Fracture risk assessment by the FRAX
model
E. V. McCloskey, N. C. Harvey, H. Johansson, Mattias Lorentzon, E. Liu, Liesbeth Vandenput, W. D. Leslie, J. A. Kanis
Climacteric - 2022 -
Osteoporosis treatment in Austria-assessment of FRAX-based intervention thresholds for high and very high fracture
risk
H. P. Dimai, Helena Johansson, N. C. Harvey, Mattias Lorentzon, E. W. Liu, Liesbeth Vandenput, A. Fahrleitner-Pammer, P. Pietschmann, C. Muschitz, E. V. McCloskey, J. A. Kanis
Archives of Osteoporosis - 2022 -
Incidence of hip fracture in Saudi Arabia and the development of a FRAX
model
Y. A. L. Saleh, R. A. Sulimani, S. Alomary, Y. I. Alnajjar, Liesbeth Vandenput, E. W. Liu, Mattias Lorentzon, N. C. Harvey, E. V. McCloskey, Helena Johansson, J. A. Kanis
Archives of Osteoporosis - 2022 -
Osteoporosis epidemiology using international
cohorts
Mattias Lorentzon, B. Abrahamsen
Current Opinion in Rheumatology - 2022
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