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Karin Nilsson
Forskare
Avd för invärtesmedicin och klinisk nutritionOm Karin Nilsson
Karin Nilsson är postdoktor i Sofia Skrtics forskargrupp vid Avdelningen för invärtesmedicin och klinisk nutrition. Hon disputerade i maj 2023 med avhandlingen “NOTUM and RSPO3 in Bone – WNT signaling modulators regulating the skeleton”. Hennes forskning fokuserar främst på att identifiera gener som kan reglera benmassa i syfte att hitta nya behandlingsmål mot osteoporos
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Membrane-initiated estrogen receptor-α signaling in the hypothalamus regulates trabecular bone in femur in female
mice
Yiwen Jiang, Karin Horkeby, Petra Henning, Karin Nilsson, Jianyao Wu, Lei Li, Sofia Moverare Skrtic, Claes Ohlsson, Marie Lagerquist
Journal of Endocrinology - 2026 -
Gut microbiota transplantation from young adult mice fails to restore low bone and muscle mass in old
mice.
Lina Lawenius, Daniel Hägg, Karin Horkeby, Karin Nilsson, Jianyao Wu, Louise Grahnemo, Claes Ohlsson, Klara Sjögren
American journal of physiology. Endocrinology and metabolism - 2026 -
Role of Complement Component 9 in Bone Health: Causal Evidence in Humans and Mechanistic Studies in
Mice.
Claes Ohlsson, Anna Törnqvist, Karin Nilsson, Maria Nethander, Jianyao Wu, Lei Li, Antti Koskela, Sofia Moverare Skrtic
Calcified tissue international - 2026 -
Identification of ephrin-A1-EphA2 signalling as a potential target for fracture
prevention.
Sofia Moverare Skrtic, Maria Nethander, Lei Li, Nelson Tsz Long Chu, Ostap Dregval, Xin Tian, Karin Nilsson, Petra Henning, Ulf Lerner, Andrei Chagin, Claes Ohlsson
Nature communications - 2026 -
WNT16 Overexpression is Insufficient to Counteract Inflammation-induced Bone Loss in Female
Mice
Karin Nilsson, Petra Henning, Marie Lagerquist, Jianyao Wu, Marta Bally, Ulf Lerner, Inger Gjertsson, Claes Ohlsson, Sofia Moverare Skrtic
Calcified Tissue International - 2026 -
Treatment with the <i>Bifidobacterium longum Strain</i> DSM 32947 Increases Bone Mineral Density in Female
Mice
Claes Ohlsson, Daniel Hägg, Karin Horkeby, Karin Nilsson, Lina Lawenius, Jianyao Wu, Antti Koskela, Juha Tuukkanen, Louise Grahnemo, Ludwig Ermann Lundberg, Stefan Roos, Klara Sjögren
CALCIFIED TISSUE INTERNATIONAL - 2025 -
Membrane-initiated estrogen receptor-α signaling in osteoblasts is crucial for normal regulation of the cortical bone in female
mice
Yiwen Jiang, Karin Horkeby, Petra Henning, Jianyao Wu, Karin H. Nilsson, Lina Lawenius, Sofia Moverare-Skrtic, Priti Gupta, Cecilia Engdahl, Antti Koskela, Juha Tuukkanen, Lei Li, Claes Ohlsson, Marie K Lagerquist
BONE RESEARCH - 2025 -
The beneficial effects of a probiotic mix on bone and lean mass are dependent on the diet in female
mice.
Claes Ohlsson, Lina Lawenius, Yiwen Jiang, Karin Horkeby, Jianyao Wu, Karin H. Nilsson, Antti Koskela, Juha Tuukkanen, Sofia Movérare-Skrtic, Petra Henning, Klara Sjögren
Scientific Reports - 2025 -
GREM2 inactivation increases trabecular bone mass in
mice
Karin H. Nilsson, Petra Henning, Jianyao Wu, Klara Sjögren, Ulf H Lerner, Claes Ohlsson, Sofia Moverare-Skrtic
Scientific Reports - 2024 -
Vitamin A enhanced periosteal osteoclastogenesis is associated with increased number of tissue-derived macrophages/osteoclast
progenitors
Petra Henning, Anna Westerlund, Karin Horkeby, Vikte Lionikaite, Karin H. Nilsson, Sofia Movérare-Skrtic, H. Herschel Conaway, Ulf H Lerner
Journal of Biological Chemistry - 2024 -
Dietary Progesterone Contributes to Intratissue Levels of Progesterone in Male
Mice
Hannah Colldén, Malin Hagberg Thulin, A. Landin, Karin Horkeby, Marie Lagerquist, Jianyao Wu, Karin H. Nilsson, Louise Grahnemo, Matti Poutanen, H. Ryberg, Liesbeth Vandenput, Claes Ohlsson
Endocrinology - 2023 -
B4GALNT3 regulates glycosylation of sclerostin and bone
mass
Sofia Moverare-Skrtic, J. Voelkl, Karin H. Nilsson, Maria Nethander, T. T. D. Luong, I. Alesutan, Lei Li, Jianyao Wu, Karin L Horkeby, Marie K Lagerquist, A. Koskela, J. Tuukkanen, J. H. Tobias, Ulf H Lerner, Petra Henning, Claes Ohlsson
eBioMedicine - 2023 -
NOTUM and RSPO3 in Bone - WNT signaling modulators regulating the
skeleton
Karin H. Nilsson
2023 -
Membrane estrogen receptor alpha signaling modulates the sensitivity to estradiol treatment in a dose- and tissue- dependent
manner
Yiwen Jiang, Karin L Horkeby, Petra Henning, Jianyao Wu, Lina Lawenius, Cecilia Engdahl, Priti Gupta, Sofia Moverare-Skrtic, Karin H. Nilsson, E. Levin, Claes Ohlsson, Marie K Lagerquist
Scientific Reports - 2023 -
Bone-Derived IGF-I Regulates Radial Bone Growth in Adult Male
Mice
Johan Svensson, Klara Sjögren, Lina Lawenius, A. Koskela, J. Tuukkanen, Karin H. Nilsson, Sofia Moverare-Skrtic, Claes Ohlsson
Endocrinology - 2023 -
Development of a synbiotic that protects against ovariectomy-induced trabecular bone
loss
Lina Lawenius, Karin L. Gustafsson, Jianyao Wu, Karin H. Nilsson, Sofia Moverare-Skrtic, E. M. Schott, M. J. Soto-Giron, G. V. Toledo, Klara Sjögren, Claes Ohlsson
American Journal of Physiology-Endocrinology and Metabolism - 2022 -
Induced inactivation of Wnt16 in young adult mice has no impact on osteoarthritis
development.
Anna E Törnqvist, Karin H. Nilsson, Lei Li, Claes Ohlsson, Sofia Movérare-Skrtic
PloS one - 2022 -
A tissue-specific role of membrane-initiated ERα signaling for the effects of
SERMs
Karin L. Gustafsson, Sofia Movérare-Skrtic, Helen H. Farman, Cecilia Engdahl, Petra Henning, Karin H. Nilsson, Julia M. Scheffler, Edina Sehic, Ulrika Islander, E. Levin, Claes Ohlsson, Marie K Lagerquist
Journal of Endocrinology - 2022 -
Estradiol and RSPO3 regulate vertebral trabecular bone mass independent of each
other
Karin H. Nilsson, Jianyao Wu, Karin L. Gustafsson, Maha El Shahawy, A. Koskela, J. Tuukkanen, J. Tuckermann, Petra Henning, Ulf H Lerner, Claes Ohlsson, Sofia Movérare-Skrtic
American journal of physiology. Endocrinology and metabolism - 2022 -
RSPO3 is important for trabecular bone and fracture risk in mice and
humans
Karin H. Nilsson, Petra Henning, Maha El Shahawy, Maria Nethander, T. L. Andersen, C. Ejersted, Jianyao Wu, Karin L. Gustafsson, A. Koskela, J. Tuukkanen, P. P. C. Souza, J. Tuckermann, Mattias Lorentzon, Linda Engström Ruud, T. Lehtimaki, J. H. Tobias, S. R. Zhou, Ulf H Lerner, J. B. Richards, Sofia Moverare-Skrtic, Claes Ohlsson
Nature Communications - 2021 -
WNT16 is Robustly Increased by Oncostatin M in Mouse Calvarial Osteoblasts and Acts as a Negative Feedback Regulator of Osteoclast Formation Induced by Oncostatin
M
Petra Henning, Sofia Moverare-Skrtic, Anna Westerlund, P. P. C. de Souza, T. Floriano-Marcelino, Karin H. Nilsson, Maha El Shahawy, Claes Ohlsson, Ulf H Lerner
Journal of Inflammation Research - 2021 -
Osteocyte- and late osteoblast-derived NOTUM reduces cortical bone mass in
mice
Karin H. Nilsson, Petra Henning, Maha El Shahawy, Jianyao Wu, A. Koskela, J. Tuukkanen, C. Perret, Ulf H Lerner, Claes Ohlsson, Sofia Moverare-Skrtic
American Journal of Physiology-Endocrinology and Metabolism - 2021 -
Arginine site 264 in murine estrogen receptor alpha is dispensable for the regulation of the
skeleton.
Karin L. Gustafsson, Helen H. Farman, Karin H. Nilsson, Petra Henning, Sofia Movérare-Skrtic, Vikte Lionikaite, Lina Lawenius, Cecilia Engdahl, Claes Ohlsson, Marie K Lagerquist
American journal of physiology. Endocrinology and metabolism - 2021 -
Wnt16 Overexpression in Osteoblasts Increases the Subchondral Bone Mass but has no Impact on Osteoarthritis in Young Adult Female
Mice
Anna E Törnqvist, Louise Grahnemo, Karin H. Nilsson, Thomas Funck-Brentano, Claes Ohlsson, Sofia Movérare-Skrtic
Calcified Tissue International - 2020 -
Pasteurized Akkermansia muciniphila protects from fat mass gain but not from bone
loss
Lina Lawenius, Julia M. Scheffler, Karin L. Gustafsson, Petra Henning, Karin H. Nilsson, Hannah Colldén, Ulrika Islander, H. Plovier, P. D. Cani, W. M. de Vos, Claes Ohlsson, Klara Sjögren
American Journal of Physiology-Endocrinology and Metabolism - 2020 -
Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and
Fractures
J. Zheng, W. Maerz, I. Gergei, M. Kleber, C. Drechsler, C. Wanner, V. Brandenburg, S. Reppe, K. M. Gautvik, C. Medina-Gomez, E. Shevroja, A. Gilly, Y. C. Park, G. Dedoussis, E. Zeggini, Mattias Lorentzon, Petra Henning, Ulf H Lerner, Karin H. Nilsson, Sofia Moverare-Skrtic, D. Baird, B. Elsworth, L. Falk, A. Groom, T. D. Capellini, E. Grundberg, Maria Nethander, Claes Ohlsson, G. D. Smith, J. H. Tobias
Journal of Bone and Mineral Research - 2019 -
Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in
humans
Sofia Moverare-Skrtic, Karin H. Nilsson, Petra Henning, Thomas Funck-Brentano, Maria Nethander, F. Rivadeneira, G. C. Nunes, A. Koskela, J. Tuukkanen, J. Tuckermann, C. Perret, P. P. C. Souza, Ulf H Lerner, Claes Ohlsson
Faseb Journal - 2019 -
NOTUM inhibition increases endocortical bone formation and bone
strength
Robert Brommage, J. Liu, P. Vogel, F. Mseeh, A. Y. Thompson, D. G. Potter, M. K. Shadoan, G. M. Hansen, S. Jeter-Jones, J. Cui, D. Bright, J. P. Bardenhagen, D. D. Doree, Sofia Moverare-Skrtic, Karin H. Nilsson, Petra Henning, Ulf H Lerner, Claes Ohlsson, A. T. Sands, J. E. Tarver, D. R. Powell, B. Zambrowicz, Q. Y. Liu
Bone Research - 2019 -
Porcupine inhibitors impair trabecular and cortical bone mass and strength in
mice
Thomas Funck-Brentano, Karin H. Nilsson, Robert Brommage, Petra Henning, Ulf H Lerner, A. Koskela, J. Tuukkanen, M. Cohen-Solal, Sofia Moverare-Skrtic, Claes Ohlsson
Journal of Endocrinology - 2018 -
WNT16 overexpression partly protects against glucocorticoid-induced bone
loss
Claes Ohlsson, Karin H. Nilsson, Petra Henning, Jianyao Wu, Karin L. Gustafsson, Matti Poutanen, Ulf H Lerner, Sofia Moverare-Skrtic
American Journal of Physiology-Endocrinology and Metabolism - 2018 -
ER alpha expression in T lymphocytes is dispensable for estrogenic effects in
bone
Karin L. Gustafsson, Karin H. Nilsson, Helen H. Farman, Vikte Lionikaite, Petra Henning, Jianyao Wu, Sara H Windahl, Ulrika Islander, Sofia Moverare-Skrtic, Klara Sjögren, Hans Carlsten, Claes Ohlsson, Marie Lagerquist
Journal of Endocrinology - 2018 -
Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult
mice.
Claes Ohlsson, Petra Henning, Karin H. Nilsson, Jianyao Wu, Karin L. Gustafsson, Klara Sjögren, Anna E Törnqvist, Antti Koskela, Fu-Ping Zhang, Marie Lagerquist, Matti Poutanen, Juha Tuukkanen, Ulf H Lerner, Sofia Movérare-Skrtic
The Journal of endocrinology - 2018