University of Gothenburg
Sahlgrenska Center for Cancer Research
Researchers discuss in lab at Sahlgrenska Center for Cancer Research
Researchers discuss in lab at Sahlgrenska Center for Cancer Research
Photo: Emelie Asplund
  2. Sahlgrenska Center for Cancer Research
  3. Research Groups

Research Groups

Sahlgrenska Center for Cancer Research houses 30 research groups and their research is divided into four main research areas: Cancer genomics, Basic disease mechanisms, Molecular pathology and therapeutics as well as Tumor immunology. All research groups at the centre have access to biobanks of a large variety of cancer diagnoses, together with an advanced collection of modern equipment.

Cancer genomics

Within the research area Cancer Genomics, our researchers contribute to the understanding of the alterations to the genetic material, the DNA, in cancer cells. The researchers use both array technologies, fluorescence in-situ hybridization, chromosome painting techniques and next-generation sequencing. These techniques help us to investigate important information on the genetic cause of tumors.

Research project/group
Stenman group
Research on salivary gland tumour – genetics and pathology.
Research project/group
Carén group
Research on epigenetic control within brain tumours from children and adults.
Research project/group
Helou group
Research on prognostic and predictive biomarkers in breast and ovarian cancer.

Basic disease mechanisms/tumour biology

Cancers are complex organs which require multiple mutations to develop. Modelling of tumours, in culture or in animal models, enables in-depth studies of the cause, treatment and prevention of cancer. Within this research area, our researchers investigate how different cancer types develop, as well as for example resistance development to chemotherapy and the role of antioxidants in cancer.

Research project/group
Sayin group
Research on lung cancer and metabolomics, using mouse models.
Research project/group
Naredi group
Research on clinical obstacles within cancer and insulin signalling biology.
Research project/group
M. Nilsson group
Research on mechanisms of pathogenesis - biomarkers and treatment strategies.
Research project/group
Lindahl group
Research project/group
Crescitelli group
Research project/group
Guibentif group
Research project/group
Åman group
Research on FET fusion oncoproteins and FET-SWI/SNF interactions.
Research project/group
Jaako group
Research project/group
Wiel group

Molecular pathology and therapeutics

Within the Molecular pathology and therapeutics research area, the development of new biomarkers or methods to study biomarkers are being investigated by our researchers. These include biomarkers in the blood or other routine diagnostic samples from patients with melanoma, gynecological cancers, childhood cancers and prostate cancer.

Research project/group
Ståhlberg group
Research on quality of life within FET fusion oncogenes and sarcomas.
Research project/group
Dalin group
Research on circulating tumor DNA as a biomarker for treatment response.
Research project/group
Sundfeldt group
Research on biomarkers and early detection of epithelial ovarian cancer (EOC).
Research project/group
Forssell-Aronsson grp.
Research on biomarkers and radiobiological effects on tumour tissue.
Research project/group
Landberg group
Research on tumour biology and endocrine treatments within breast cancer.
Research project/group
Johansson group
Research on the pathology of renal cell carcinoma of the kidney.
Research project/group
Welén group
Research on castration-resistant prostate cancer (CRPC) and (ADT).
Research project/group
P-O. Andersson group
Research project/group
Elias group
Research on Neuro-endocrine tumours and Somatostatin receptors.
Research project/group
M. Andersson group
Research project/group
Parris group
Photo: Emelie Asplund

Tumour immunology

Our researchers within the Tumour Immunology research area investigate the development of treatments that can prevent the reemergence of leukemia, by activating immune cells. Immune-humanized mouse models and other novel animal models, therapies and clinical trials against leukemia and solid cancers, such as melanoma, are being developed as well.

Research project/group
Hellstrand group
Research on immunotherapy with histamine dihydrochloride.
Research project/group
Martner group
Research on cytotoxic lymphocytes in Myeloid leukemia (AML and CML).
Research project/group
Levin group
Research project/group
J. Nilsson group
Research on PDX models (Avatar mice) and Malignant melanoma.
Research project/group
Olofsson Bagge group
Research on Malignant melanoma and Breast cancer – QOL, immunology.
Photo: Emelie Asplund
Research project/group
Bergh Thorén group
Research on NK cells - Myeloid leukemia and inflammatory diseases.
Research project/group
Raghavan group
Photo: Emelie Asplund
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