Based on the clinical presentation of SC, the treatment has four main tenets:
1) Elimination and secondary prophylaxis of streptococcal infection with penicillin.
2) Symptomatic treatment of the involuntary movements and incoordination with anticonvulsants (e.g. Sodium valproate or carbamazepine) or neuroleptics (e.g. Risperidone, Haloperidol, or pimozide) however neuroleptics must be used with caution in SC patients because of the increased risk of extrapyramidal side effects. Although there are anecdotal reports of success in the literature relating to steroids, plasma exchange and IVIG, there is insufficient evidence to support any of these as routine treatment.
3) Symptomatic treatment of psychiatric complications.
4) Supportive measures: Supportive work with the families and liaising with education to ensure that the child’s condition is well understood and supported in school.