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Sara Svensson

About Sara Svensson

Sara Svensson obtained her Master of Science in Biotechnology from Chalmers University of Technology in 2006. Her master thesis was performed at the UK Tissue Engineering Centre at the University of Manchester and investigated protein adsorption and endothelial cell attachment to bacterial cellulose. Her interest for cell-material interactions led her to the Department of Biomaterials in 2006, where she started a PhD project within the BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy in 2008.

Reasearch interests: •Nanostructures and the role they play in host defence and bacterial adhesion and survival.

•The mechanism of action of nanostructured noble metal coatings that reduce infections in the clinic.

•The tissue/implant interface, in particular by utilizing the laser microdissection (LMD) technique to pinpoint cells at different distances away from the implant surface for subsequent gene expression analysis.  

Figure S2: Multiple SEM images taken with 5000x magnification stitched together for an overview of Staphylococcus epidermidis growth and biofilm formation on nanostructured and smooth Au surfaces after 2, 24, and 48 hours of static incubation. Abbreviations: Nano, nanostructured gold surface; SEM, scanning electron microscopy; Smooth, smooth gold surface

Published in: Svensson S, Forsberg M, Hulander M, Vazirisani F, Palmquist A, Lausmaa J, Thomsen P, Trobos M. The role of nanostructured gold surfaces on monocyte activation and Staphylococcus epidermidis biofilm formation. International Journal of Nanomedicine, January 2014

Animation: The bacteria-surface interface on smooth and nanostructured gold surfaces were visualized after ion milling in a focused ion beam-scanning electron microscope (FIB-SEM). The attachment of Staphylococcus epidermidis to nanostructured gold relies on a few discrete attachment points between the bacterial cell wall and the immobilized nanoparticles, whereas the cell wall is in continuous contact with the smooth surface.

Published in: Svensson S, Forsberg M, Hulander M, Vazirisani F, Palmquist A, Lausmaa J, Thomsen P, Trobos M. The role of nanostructured gold surfaces on monocyte activation and Staphylococcus epidermidis biofilm formation. International Journal of Nanomedicine, January 2014