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Lowie Vanfleteren
Senior Lecturer/ Specialized Physician
Department of Internal Medicine and Clinical NutritionAbout Lowie Vanfleteren
About Lowie Vanfleteren
Lowie Vanfleteren is currently the head of COPD-center at the Sahlgrenska University Hospital in Gothenburg, lecturer and researcher in Pulmonary Medicine at University of Gothenburg.
In June 2005 he obtained his medical degree and shortly afterwards he started his training in internal medicine in the Atrium medical center in Heerlen (the Netherlands).
From august 2007 he was working as a resident in respiratory medicine in Maastricht University Medical Center (MUMC+), where he obtained his degree as a chest physician in august 2011. From 2011 to 2018 he worked as a chest physician in CIRO+, a center of expertise in chronic organ failure, in Horn, (the Netherlands) with secondment to the department of respiratory medicine in Maastricht University Medical Center and the Faculty of Health, Medicine and Life Sciences of Maastricht university. Next to his work in pulmonary rehabilitation, he set up collaboration with the center of home mechanical ventilation in Maastricht for the treatment of respiratory failure in advanced COPD, initiated a referral center for endobronchial lung volume reduction and lung volume reduction surgery, and set up a multidisciplinary treatment approach for severe asthma in Maastricht University Medical Hospital. In February 2015 he obtained his PhD on “COPD and comorbidities” at the university of Maastricht.
In 2018 he moved to Gothenburg, Sweden and started to work in a combination position as associate professor at the Institute of Medicine of the University of Gothenburg and as a lung physician and head of the COPD-center at Sahlgrenska University Medical Hospital in Gothenburg Sweden.
Research and international collaboration
Lowie Vanfleteren's clinical and scientific focus is on COPD. He is a principal investigator of several investigator-initiated studies and supervisor of PhD and Postdoc students.
Internationally Lowie is a member of twelve collaborative initiatives, including the American Thoracic Society and participating in the Program Committee of the Pulmonary Rehabilitation assembly. He is the representative to the Early Career Members Committee for the clinical assembly of the European Respiratory Society for 2018-2022. He is associate editor for the Journals Respiration and ERJ open research. He participates in the steering committee of the Swedish Airway register.
Awards, citations and distinctions
Lowie Vanfleteren has published over 100 scientific publications and has been invited speaker to over 80 conferences and symposias. He is a winner of several awards: European Respiratory Journal 2016 Top Reviewer; Best Abstract in Pulmonary Rehabilitation; European Respiratory Society annual meeting; Travel Award, funded by the national emphysema foundation; American Thoracic Society annual meeting; assembly of clinical problems.
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Plasma proteins associated with cardiovascular disease in relation to lung function in
SCAPIS
Andreas Frolich, Ludger Grote, Anders Gummesson, Viktor Hamrefors, Christer Janson, David Kylhammar, Eva Lindberg, Anders Linden, Mirjam Ljunggren, Hans Lennart Persson, Magnus Skold, Ellen Tufvesson, Lowie Vanfleteren, Andrei Malinovschi, Anders Blomberg, Suneela Zaigham, Per Liv, Elin Chorell, Annelie Behndig, Apostolos Bossios, Kenneth Caidahl, Anna-Carin Olin, Arne Egesten, Jan Engvall, Jonas Eriksson Strom
RESPIRATORY MEDICINE - 2025 -
Socioeconomic Status Related to Prescription of Triple Therapy and Anticholinergic Monotherapy in Patients with Chronic Obstructive Pulmonary Disease (COPD) in Sweden - A Retrospective National Registry
Study
Kjell Larsson, Staffan Betner, Barbara Fuchs, Lowie Vanfleteren, Caroline Stridsman
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE - 2025 -
Real-life impact of anti-IL5 therapy on exacerbation types in patients with obstructive lung
disease
Lowie Vanfleteren, Delphine Vauterin, Lies Lahousse
BMJ Open Respiratory Research - 2025 -
Gestational Age and Birthweight Predict Airflow Obstruction A Study from the Swedish National Airway
Register
Maria Odling, Mikael Andersson Franko, Helena Backman, Lowie Vanfleteren, Caroline Stridsman, Jon R. Konradsen
ANNALS OF THE AMERICAN THORACIC SOCIETY - 2025 -
Preserved ratio impaired spirometry, dysanapsis and airflow obstruction with low forced expiratory volume in 1 s in childhood
asthma
Caroline Stridsman, Helena Backman, Lowie Vanfleteren, Anna Asarnoj, Henrik Ljungberg, Anne Lindberg, Apostolos Bossios, Jon R. Konradsen
ERJ OPEN RESEARCH - 2025 -
The impact of bronchoscopic lung volume reduction with endobronchial valves with or without pulmonary rehabilitation on symptoms of fatigue, anxiety and depression: a multicentre randomised controlled
trial
Rein Posthuma, Marieke C. van der Molen, Anouk W. Vaes, Jorine E. Hartman, Martijn A. Spruit, Dirk-Jan Slebos, Lowie Vanfleteren
ERJ OPEN RESEARCH - 2025 -
Cardiovascular safety of biologic therapies in patients with severe asthma: a nationwide cohort
in
Frauke Van Vaerenbergh, Delphine Vauterin, Maxim Grymonprez, Lowie Vanfleteren, Guy Brusselle, Lies Lahousse
LANCET REGIONAL HEALTH-EUROPE - 2025 -
Changes in the pulmonary surfactant in patients with mild to moderate
COVID-19
Spela Kokelj, Per Larsson, Emilia Viklund, Hatice Koca Akdeva, Hanna Slogén, Lowie Vanfleteren, Bo Nilsson, Karin Fromell, Johan Westin, Anna-Carin Olin
Plos One - 2025 -
Computational Phenotyping of Obstructive Airway Diseases: A Systematic
Review
Muwada Bashir Awad Bashir, Gregorio Paolo Milani, Valentina De Cosmi, Alessandra Mazzocchi, Guo-Qiang Zhang, Rani Basna, Linnea Hedman, Anne Lindberg, Linda Ekerljung, Malin Axelsson, Lowie E G W Vanfleteren, Eva Rönmark, Helena Backman, Hannu Kankaanranta, Bright I Nwaru
Journal of Asthma and Allergy - 2025 -
Systemic pro-inflammatory response following bronchoscopic lung volume reduction using endobronchial
valves
Jorine E. Hartman, Marieke C. van der Molen, Marnix R. Jonker, Rein Posthuma, Lowie E G W Vanfleteren, Dirk-Jan Slebos, Simon D. Pouwels
European Respiratory Journal Open Research (ERJ Open Research) - 2025 -
Clinical Implications of the New Criteria for a Positive Bronchodilator Response in Children With
Asthma
Caroline Stridsman, Helena Backman, Lowie E G W Vanfleteren, Anna Asarnoj, Henrik Ljungberg, Anne Lindberg, Apostolos Bossios, Jon R. Konradsen
ACTA PAEDIATRICA - 2025 -
Remote monitoring of patients with COPD disease using a tablet system: a randomised crossover study of quality-of-life
measurements
Malte Frerichs, Huiqi Li, Anders Andersson, Kristina Andelid, Monica Crona, Lowie E G W Vanfleteren
ERJ Open Research - 2025 -
Metabolic Changes After Bronchoscopic Lung Volume Reduction With Endobronchial Valves in COPD
Patients
Marieke C. van der Molen, Rein Posthuma, Anouk W. Vaes, Martijn A. Spruit, Harry R. Gosker, Alain R. Viddeleer, Tineke P. Willems, Lowie E G W Vanfleteren, Dirk Jan Slebos, Jorine E. Hartman
Archivos de Bronconeumologia - 2025 -
Risk of exacerbations, hospitalisation, and mortality in adults with physician-diagnosed chronic obstructive pulmonary disease with normal spirometry and adults with preserved ratio impaired spirometry in Sweden: retrospective analysis of data from a nationwide cohort
study
Oscar Wallström, Caroline Stridsman, Helena Backman, Sigrid Vikjord, Anne Lindberg, Fredrik Nyberg, Lowie E G W Vanfleteren
LANCET REGIONAL HEALTH-EUROPE - 2025 -
Genome-Wide Differential Airway Gene Expression Analysis Identifies Genes Associated with COPD
Comorbidities
Alen Faiz, Else A. M. D. ter Haar, Jorine E. Hartman, Corry-Anke Brandsma, Wim Timens, Janette K. Burgess, David F. Choy, Michele A. Grimbaldeston, Lowie E G W Vanfleteren, Dirk-Jan Slebos, Maarten van den Berge, Simon D. Pouwels
LUNG - 2025 -
All-cause and cause-specific mortality in respiratory symptom clusters: a population-based multicohort
study
Daniil Lisik, Helena Backman, Hannu Kankaanranta, Rani Basna, Linnea Hedman, Linda Ekerljung, Fredrik Nyberg, Anne Lindberg, Göran Wennergren, Eva Rönmark, Bright I Nwaru, Lowie E G W Vanfleteren
Respiratory research - 2025 -
Severity of Airflow Obstruction Based on FEV<inf>1</inf>/FVC Versus FEV<inf>1</inf> Percent Predicted in the General U.S.
Population
Helena Backman, Lowie E G W Vanfleteren, David M. Mannino, Magnus Ekström
American journal of respiratory and critical care medicine - 2024 -
Key Characteristics of Asthma Patients with COVID-19 Vary Substantially by
Age
Brian Kirui, Ailiana Santosa, Huiqi Li, Lowie E G W Vanfleteren, Caroline Stridsman, Fredrik Nyberg
Journal of Asthma and Allergy - 2024 -
Exacerbation History and Risk of Myocardial Infarction and Pulmonary Embolism in
COPD.
Oskar Wallström, Caroline Stridsman, Anne Lindberg, Fredrik Nyberg, Lowie E G W Vanfleteren
Chest - 2024 -
Lung-function trajectories: relevance and implementation in clinical
practice
Erik Melén, Rosa Faner, James P. Allinson, Dinh Bui, Andrew Bush, Adnan Custovic, Judith Garcia-Aymerich, Stefano Guerra, Robab Breyer-Kohansal, Jenny Hallberg, Lies Lahousse, Fernando D. Martinez, Simon Kebede Merid, Pippa Powell, Hilary Pinnock, Sanja Stanojevic, Lowie E G W Vanfleteren, Gang Wang, Shyamali C. Dharmage, Jadwiga Wedzicha, Alvar Agusti, Alicia Abellan, Ian Adcock, Shoaib Afzal, Peter Alter, Helena Backman, Xander Bertels, Chloe Bloom, Klaus Bønnelykke, Marie Kathrin Breyer, Sandra Casas, Fan (Kian) Chung, Yunus Colak, Borja G. Cosio, Liesbeth Duijts, Leonardo Fabbri, Sara Fontanella, Elaine Fuertes, Juan Ramón Gonzalez, Raquel Granell, Sylvia Hartl, Natalia Hernandez-Pacheco, John Holloway, Deborah Jarvis, Hans Jacob Koefoed, Tessa Kole, Ashish Kumar, Arnulf Langhammer, Anne Lindberg, Maria Llopis, Anke Hilse Maitland van der Zee, Howraman Meteran, Cosetta Minelli, Bright Nwaru, Nuria Olvera, Gabriela Peralta, Andrew Ritchie, Eva Rönmark, James Ross Chapman, Júlia Sangüesa Boix, Tamara Schikowski, Vivi Schlünssen, Seif Shaheen, Torben Sigsgaard, Marie Standl, Mohammad Talaei, Anhar Ullah, Anders Ullman, Carlos Valencia-Hernandez, Maarten van den Berge, Yoni van Dijk, Jørgen Vestbo, Susanne Vijverberg, Sigrid Anna Vikjord, Claus Volgelmeier, Judith Vonk, Nazanin Zounemat Kermani
The Lancet - 2024 -
Lung Hyperinflation as Treatable Trait in Chronic Obstructive Pulmonary Disease: A Narrative
Review
Maud Koopman, Rein Posthuma, Lowie E G W Vanfleteren, Sami Simons, Frits M. E. Franssen
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE - 2024 -
Vitamin D Status and Longitudinal Changes in Body Composition in Patients with Chronic Obstructive Pulmonary Disease - A Prospective Observational
Study
Maria Minter, Jenny Van Odijk, Hanna Augustin, Felipe V. C. Machado, Frits M. E. Franssen, Martijn A. Spruit, Lowie E G W Vanfleteren
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE - 2024 -
Impact and timing of pulmonary rehabilitation in patients undergoing bronchoscopic lung volume reduction with endobronchial valves: A multicentre randomized controlled trial in patients with severe
emphysema
Marieke C. van der Molen, Rein Posthuma, Jorine E. Hartman, Hester van der Vaart, Eline Bij de Vaate, Anouk W. Vaes, Bram van den Borst, Dirk van Ranst, Martijn A. Spruit, Lowie E G W Vanfleteren, Dirk-Jan Slebos
RESPIROLOGY - 2024 -
All-cause and cause-specific mortality by spirometric pattern and sex - a population-based cohort
study
Helena Backman, Sami Sawalha, Ulf Nilsson, Linnea Hedman, Caroline Stridsman, Lowie E G W Vanfleteren, Bright I Nwaru, Nikolai Stenfors, Eva Ronmark, Anne Lindberg
THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE - 2024 -
Treatable traits in advanced emphysema patients eligible for bronchoscopic lung volume reduction with endobronchial
valves
Rein Posthuma, Marieke C. van der Molen, Jorine E. Hartman, Martijn A. Spruit, Dirk -Jan Slebos, Lowie E G W Vanfleteren, Anouk W. Vaes
RESPIRATORY MEDICINE - 2024 -
Pre- and post-vaccination characteristics and risk factors for COVID-19 outcomes in a Swedish population-based cohort of COPD
patients
Brian Kibiwott Kirui, Ailiana Santosa, Lowie E G W Vanfleteren, Huiqi Li, Stefan Franzén, Caroline Stridsman, Fredrik Nyberg
European Respiratory Journal Open Research (ERJ Open Research) - 2023 -
Regular Inhaled Corticosteroids Use May Protect Against Severe COVID-19 Outcome in
COPD
M Labor, Brian Kirui, Fredrik Nyberg, Lowie E G W Vanfleteren
The International Journal of Chronic Obstructive Pulmonary Disease - 2023 -
Endothelial function in patients with COPD: an updated systematic review of studies using flow-mediated
dilatation
A. W. Vaes, P. De Boever, F. M. E. Franssen, Nhmk Uszko-Lencer, Lowie E G W Vanfleteren, M. A. Spruit
Expert Review of Respiratory Medicine - 2023 -
Recent advances in bronchoscopic lung volume reduction for severe COPD
patients
Rein Posthuma, Anouk W. Vaes, Martijn A. Spruit, Lowie E G W Vanfleteren
CURRENT OPINION IN SUPPORTIVE AND PALLIATIVE CARE - 2023 -
COPD and multimorbidity: recognising and addressing a syndemic
occurrence
L. M. Fabbri, B. R. Celli, A. Agusti, G. J. Criner, M. T. Dransfield, M. Divo, J. K. Krishnan, L. Lahousse, M. M. de Oca, S. S. Salvi, D. Stolz, Lowie E G W Vanfleteren, C. F. Vogelmeier
Lancet Respiratory Medicine - 2023 -
Exacerbation Risk and Mortality in COPD GOLD Group A and B Patients with and without Exacerbation
History.
Lowie E G W Vanfleteren, Anne Lindberg, Caddie Zhou, Fredrik Nyberg, Caroline Stridsman
American journal of respiratory and critical care medicine - 2023 -
Differential Response to 12 Weeks of Once-Daily Tiotropium/Olodaterol Fixed Dose Combination in Patients with COPD: A Multidimensional Response Profiling in the TORRACTO
Study
R. Posthuma, Lowie E G W Vanfleteren, S. Gaffron, A. W. Vaes, F. M. E. Franssen, M. A. Spruit
International Journal of Chronic Obstructive Pulmonary Disease - 2023 -
Hospital Admission Rates in Patients with COPD Throughout the COVID-19
Pandemic
Niklas Andreen, J. Westin, Lowie E G W Vanfleteren
International Journal of Chronic Obstructive Pulmonary Disease - 2023 -
High prevalence of interstitial lung abnormalities in middle-aged
never-smokers
I. Pesonen, F. Johansson, Åse (Allansdotter) Johnsson, A. Blomberg, Marianne Boijsen, John Brandberg, K. Cederlund, A. Egesten, ÖI Emilsson, J. E. Engvall, A. Frolich, E. Hagström, E. Lindberg, A. Malinovschi, N. Stenfors, E. Swahn, H. Tanash, R. Themudo, Kjell Torén, Lowie E G W Vanfleteren, P. Wollmer, S. Zaigham, C. J. Östgren, C. M. Sköld
European Respiratory Journal Open Research (ERJ Open Research) - 2023 -
Activation of the Complement and Coagulation Systems in the Small Airways in
Asthma
Spela Kokelj, J. Ostling, K. Fromell, Lowie E G W Vanfleteren, H. K. Olsson, K. N. Ekdahl, B. Nilsson, Anna-Carin Olin
Respiration - 2023 -
Underdiagnosis and misclassification of COPD in Sweden - A Nordic Epilung
study
M. Axelsson, H. Backman, Bright I Nwaru, C. Stridsman, Lowie E G W Vanfleteren, L. Hedman, P. Piirila, J. Jalasto, A. Langhammer, Hannu Kankaanranta, Madeleine Rådinger, Linda Ekerljung, E. Ronmark, A. Lindberg
Respiratory Medicine - 2023 -
The AGE-RAGE Axis and the Pathophysiology of Multimorbidity in
COPD
N. L. Reynaert, Lowie E G W Vanfleteren, T. N. Perkins
Journal of Clinical Medicine - 2023 -
Clinical impact of routine sleep assessment by peripheral arterial tonometry in patients with
COPD
D. Hansson, Anders Andersson, Lowie E G W Vanfleteren, Kristina Andelid, Ding Zou, Jan A Hedner, Ludger Grote
ERJ Open Research - 2023 -
Biomarker-based clustering of patients with chronic obstructive pulmonary
disease
Lowie E G W Vanfleteren, Julie Weidner, F. M. E. Franssen, S. Gaffron, N. L. Reynaert, E. F. M. Wouters, M. A. Spruit
ERJ Open Research - 2023 -
Gender Differences in Vitamin D Status and Determinants of Vitamin D Insufficiency in Patients with Chronic Obstructive Pulmonary
Disease
Maria Minter, Hanna Augustin, Jenny Van Odijk, Lowie E G W Vanfleteren
Nutrients - 2023 -
Cause-specific Death in Chronic Airway Obstruction and Restrictive Spirometric
Pattern.
Helena Backman, Sami Sawalha, Ulf Nilsson, Linnea Hedman, Caroline Stridsman, Lowie E G W Vanfleteren, Bright I Nwaru, Nikolai Stenfors, Eva Rönmark, Anne Lindberg
Annals of the American Thoracic Society - 2022 -
Restricted spirometry and cardiometabolic comorbidities: results from the international population based BOLD
study
Katarzyna Kulbacka-Ortiz, F. J. J. Triest, F. M. E. Franssen, E. F. M. Wouters, M. Studnicka, W. M. Vollmer, B. Lamprecht, P. G. J. Burney, A. F. S. Amaral, Lowie E G W Vanfleteren
Respiratory research - 2022 -
Differential Outcomes Following 4 Weeks of Aclidinium/Formoterol in Patients with COPD: A Reanalysis of the ACTIVATE
Study
M. Koopman, F. M. E. Franssen, S. Gaffron, H. Watz, T. Troosters, J. Garcia-Aymerich, P. Paggiaro, E. Molins, M. Moya, L. van Burk, D. Maier, E. G. Gil, E. F. M. Wouters, Lowie E G W Vanfleteren, M. A. Spruit
International Journal of Chronic Obstructive Pulmonary Disease - 2022 -
Uncontrolled asthma predicts severe COVID-19: a report from the Swedish National Airway
Register.
Johanna Karlsson Sundbaum, Jon R Konradsen, Lowie E G W Vanfleteren, Sten Axelsson Fisk, Christophe Pedroletti, Yvonne Sjöö, Jörgen Syk, Therese Sterner, Anne Lindberg, Alf Tunsäter, Fredrik Nyberg, Ann Ekberg-Jansson, Caroline Stridsman
Therapeutic advances in respiratory disease - 2022 -
Changes in lung function in European adults born between 1884 and 1996 and implications for the diagnosis of lung disease: a cross-sectional analysis of ten population-based
studies.
James P Allinson, Shoaib Afzal, Yunus Çolak, Debbie Jarvis, Helena Backman, Maarten van den Berge, H Marike Boezen, Marie-Kathrin Breyer, Robab Breyer-Kohansal, Guy Brusselle, Otto C Burghuber, Rosa Faner, Sylvia Hartl, Lies Lahousse, Arnulf Langhammer, Bo Lundbäck, Bright I Nwaru, Eva Rönmark, Sigrid A Aalberg Vikjord, Judith M Vonk, Sara R A Wijnant, Peter Lange, Børge G Nordestgaard, Nuria Olvera, Alvar Agusti, Gavin C Donaldson, Jadwiga A Wedzicha, Jørgen Vestbo, Lowie E G W Vanfleteren
The Lancet. Respiratory medicine - 2022 -
Computational phenotyping of obstructive airway diseases: protocol for a systematic
review.
Muwada Bashir Awad Bashir, Rani Basna, Guo-Qiang Zhang, Helena Backman, Anne Lindberg, Linda Ekerljung, Malin Axelsson, Linnea Hedman, Lowie E G W Vanfleteren, Bo Lundbäck, Eva Rönmark, Bright I Nwaru
Systematic reviews - 2022 -
Reduction of Lung Hyperinflation Improves Cardiac Preload, Contractility, and Output in Emphysema A Clinical Trial in Patients Who Received Endobronchial
Valves
M. C. van der Molen, J. E. Hartman, Lowie E G W Vanfleteren, H. A. M. Kerstjens, J. P. van Melle, T. P. Willems, D. J. Slebos
American Journal of Respiratory and Critical Care Medicine - 2022 -
The HUNT study: Association of comorbidity clusters with long-term survival and incidence of exacerbation in a population-based Norwegian COPD
cohort
S. A. A. Vikjord, B. Brumpton, X. M. Mai, S. Romundstad, A. Langhammer, Lowie E G W Vanfleteren
Respirology - 2022 -
Clustering based on comorbidities in patients with chronic heart failure: an illustration of clinical
diversity
Nhmk Uszko-Lencer, D. J. A. Janssen, S. Gaffron, Lowie E G W Vanfleteren, E. Janssen, C. Werter, F. M. E. Franssen, E. F. M. Wouters, S. Rechberger, H. P. B. La Rocca, M. A. Spruit
ESC Heart Failure - 2022 -
ERS International Congress 2021: highlights from the Respiratory Clinical Care and Physiology
Assembly
T. Gille, P. Sivapalan, G. Kaltsakas, S. B. Kolekar, M. Armstrong, R. Tuffnell, R. A. Evans, G. Vagheggini, L. H. Degani-Costa, C. Vicente, N. Das, V. Poberezhets, C. Rolland-Debord, S. Bayat, I. Vogiatzis, F. M. E. Franssen, H. Pinnock, Lowie E G W Vanfleteren
European Respiratory Journal Open Research (ERJ Open Research) - 2022
More publications
We have limited the number of publications on this page. Visit GUP (The Publication Database for Gothenburg University) to find more publications.