Beidong Liu


Institutionen för kemi och molekylärbiologi
031-786 25 99
Medicinaregatan 7 B
41390 Göteborg
Box 462
40530 Göteborg

Om Beidong Liu

Current position •Full professor (part-time), from 2023-09-01 • Full professor, from 2023-01-01 • Director of the Center for Large-scale cell-based screening (cmb.gu.se/english/research/microbiology/center-for-large-scale-cell-based-screening), from 2015-09-01

Research My present research interest is focused on deciphering mechanisms underlying the formation of membraneless originals and their roles in aging and aging-related diseases by developing and applying novel high-content screening techniques using yeast (Saccharomyces cerevisiae) as a model system. The powerful high throughput screening approach, developed in my group, enables me to study all the possible combinations between a phenotypic reporter of choice and a collection of gene mutants throughout the yeast genome in a few months (while a conventional manual test would take more than several decades). This approach makes it possible to pull out almost all components being part of any specific biological machinery and allows for an unbiased, genome-wide, identification of components and networks involved in, for example, stress granule regulation, protein phase separation condensate formation, protein quality control machinery, protein aggregate formation and inheritance and epigenetic silencing.