A patient reporting in his mobile phone.
Photo: Karin Kjellgren

Perhit - PERson-centredness in hypertension management using information technology

Research project
Active research
Project size
15 million
Project period
2018 - 2024
Project owner
The Institute of Health and Care Sciences

Kamprad Foundation, Swedish Research Council, Heart Lung Foundation, The Research Council of Southeast Sweden, GPCC

Short description

Randomized and controlled trial in primary care based on patient participation in hypertension care through daily self-monitoring of blood-pressure, symptoms, side-effects and life-style. An interactive web-based system for use in mobile phones is used to support self-management of hypertension. Results from a pilot study with 50 participants could show that the patients during follow-up consultations took on an active role, sharing to a large extent observations, reflections and questions. This means a different foundation for what the conversation may be all about– and for what subjects can be discussed. Further, after a eight weeks use of the system significant lower blood pressure could be shown. PERHIT tests use of the system in a larger group, about 900 patients are randomized to different groups.

Illustration showing the steps involved in a patient measuring blood pressure and reporting it.
Photo: Illustratör: Thomas Möller

The system consists of: (a) mobile phone (patient's own) for self-reporting of blood pressure, symptoms, medication adherence, side effects, lifestyle and well-being along with individualized reminders and encouraging messages for better lifestyles; (b) sphygmomanometer; (c) database for real-time recording of self-reported data entered by mobile phone (d) web-based feedback system that graphically displays collected self-reported data via the Internet accessible to patient and doctor/nurse.

Hallberg et al. Phases in development of an interactive mobile phone-based system to support self-management of hypertension, Integrated Blood Pressure Control, 2014 (7):19-28.

Scientific publications

Andersson U, Nilsson PM, Kjellgren K, Ekholm M, Midlöv P. Associations between daily home blood pressure measurements and self-reports of lifestyle and symptoms in primary care: the PERHIT study. Scand J Prim Health Care. 2024 Mar 26:1-9. doi: 10.1080/02813432.2024.2332745. Epub ahead of print. PMID: 38529930.

Hanna Vestala, Marcus Bendtsen, Patrik Midlöv, Karin Kjellgren & Ann
Catrine Eldh (12 Jan 2024): Effects of an interactive web-based support system via mobile phone on preference-based patient participation in patients living with hypertension – a randomized controlled trial in primary care, Scandinavian Journal of Primary Health Care, DOI: 10.1080/02813432.2023.2301567.

Andersson U, Nilsson PM, Kjellgren K, Harris K, Chalmers J, Ekholm M, Midlöv P. Variability in home blood pressure and its association with renal function and pulse pressure in patients with treated hypertension in primary care. J Hum Hypertens. 2023 Nov 15. doi: 10.1038/s41371-023-00874-2. Online ahead of print.

Ulrika Andersson, Peter M. Nilsson, Karin Kjellgren, Mikael Hoffmann, Andre Wennersten, Patrik Midloev (2023) PERson-centredness in Hypertension management using Information Technology: a randomized controlled trial in primary care Journal of Hypertension, Vol. 41, s. 246-253.

Ulrika Andersson, Ulrika Bengtsson, Agneta Ranerup, Patrik Midlov, Karin Kjellgren (2021) Patients and Professionals as Partners in Hypertension Care: Qualitative Substudy of a Randomized Controlled Trial Using an Interactive Web-Based System Via Mobile Phone Journal of Medical Internet Research, Vol. 23.

Midlöv P, Nilsson PM, Bengtsson U, Hoffmann M, Wennersten A, Andersson A, Malmqvist U, Steen Carlsson K, Ranerup A, Kjellgren K. PERson-centredness in Hypertension Management Using Information Technology (PERHIT): A Protocol for a Randomised Controlled Trial in Primary Health Care. Blood Press 2019 Dec 9[Online ahead of print],1-8, DOI: 10.1080/08037051.2019.1697177.


Patrik Midlöv, Professor Lund University

Karin Kjellgren, Professor emerita, Linköping University

Peter Nilsson, Professor Lund University

Agneta Ranerup, Professor, University of Gothenburg

Ulrika Bengtsson, Senior Lecturer, University of Gothenburg

Mikael Hoffman, PhD, Linköping University

Ulrika Andersson, PhD, Lund University

Katarina Steen Carlsson, Lund University