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- Anders Elfvin
Anders Elfvin
Professor/ Chief Physician
Department of PediatricsAbout Anders Elfvin
Summary in english Overall aim is to identify changes over time regarding invasive infections in infancy, to identify patterns in early inflammatory markers and microbial flora related to development of necrotizing enterocolitis (NEC) and sepsis, and to prevent sequelae as intestinal failure and osteopenia in children post NEC
The overall aim is currently addressed in four specific aims:
1. To identify changes in the panorama of bacteria, incidence of disease and mortality of all cases of sepsis and meningitis in new-born infants in the Gothenburg area between the years 1997-2017, compared to the years 1975-1986 and 1987-1996.
2. To in a prospective cohort study identify early patterns in signal proteins such as angiogenetic regulatory proteins, oral- and intestinal flora related to an increased risk of developing NEC and sepsis among preterm infants.
3. To identify differences in the intestinal flora, bone mass and BMI at 4 and 7 years of age in children born preterm with a history of NEC compared to preterm infants not diagnosed with NEC
4. To clarify whether children diagnosed with NEC between the years of 1987-2009 have an increased risk of vitamin-D deficiency, rickets and fractures during childhood compared to children born at the same gestational age without NEC.
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Centralisation of extremely preterm births and decreased early postnatal mortality in Sweden, 2004-2007 versus
2014-2016
Christian Gadsboll, Lars J. Bjorklund, Mikael Norman, Thomas Abrahamsson, Magnus Domellof, Anders Elfvin, Aijaz Farooqi, Lena Hellstrom-Westas, Stellan Hakansson, Karin Kallen, Erik Normann, Fredrik Serenius, Karin Sävman, Petra Um-Bergstrom, Ulrika Aden, David Ley
ACTA PAEDIATRICA - 2024 -
Gut microbiota differences in five-year-old children that were born preterm with a history of necrotizing enterocolitis: A pilot
trial
Amanda Magnusson, Seyedeh Marziyeh Jabbari Shiadeh, Maryam Ardalan, Diana Swolin-Eide, Anders Elfvin
ISCIENCE - 2024 -
Ultra-high-frequency ultrasound (48-70 MHz) is a promising tool for improved gastrointestinal diagnostics in
infants
Ronni Bengtson Jacobsen, Hanna Hebelka, Vladimir Gatzinsky, Anders Elfvin, Frida Dangardt
ACTA PAEDIATRICA - 2024 -
Glycemic control assessed by continuous glucose monitoring during pregnancy in women with type 1 diabetes and its association with preeclampsia, an observational Swedish cohort
study
Linda Englund-Ögge, Annika Dotevall, Anders Elfvin, Ulrika Sandgren, Karolina Linden, Linnea Bohlin, Bernadette Wallstersson, Marten Sjodell, Jaine Augustinsson, Anna Hagman
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA - 2024 -
Antibiotic Use in Late Preterm and Full-Term
Newborns
Johan Gyllensvärd, Marie Studahl, Lars Gustavsson, Elisabet Hentz, Karin Akesson, Huiqi Li, Mikael Norman, Anders Elfvin
JAMA NETWORK OPEN - 2024 -
Maternal pheochromocytoma and childbirth in Sweden 1973-2015: a population-based study on short and long-term
outcome
Lisa Gunnesson, Oskar Ragnarsson, Maria Nilsson, Verena Sengpiel, Anders Elfvin, Erik Elias, Andreas Muth
ENDOCRINE - 2024 -
Effect of human milk-based fortification in extremely preterm infants fed exclusively with breast milk: a randomised controlled
trial
Georg Bach Jensen, Magnus Domellof, Fredrik Ahlsson, Anders Elfvin, Lars Naver, Thomas Abrahamsson
ECLINICALMEDICINE - 2024 -
One-year survival and outcomes of infants born at 22 and 23 weeks of gestation in Sweden 2004-2007, 2014-2016 and
2017-2019
A. Farooqi, S. Hakansson, F. Serenius, K. Kallen, L. Bjorklund, E. Normann, M. Domellof, U. Aden, T. Abrahamsson, Anders Elfvin, K. Savman, P. U. Bergstrom, O. Stephansson, D. Ley, L. Hellstrom-Westas, M. Norman
Archives of Disease in Childhood-Fetal and Neonatal Edition - 2024 -
Factors associated with the increased incidence of necrotising enterocolitis in extremely preterm infants in Sweden between two population-based national cohorts (2004-2007 vs
2014-2016)
P. Challis, K. Källén, L. Björklund, Anders Elfvin, A. Farooqi, S. Håkansson, D. Ley, M. Norman, E. Normann, F. Serenius, Karin Sävman, L. Hellström-Westas, P. Um-Bergström, U. Ådén, T. Abrahamsson, M. Domellöf
Archives of Disease in Childhood-Fetal and Neonatal Edition - 2024 -
Body composition and bone mass among 5-year-old survivors of necrotizing
enterocolitis
Amanda Magnusson, Diana Swolin-Eide, Anders Elfvin
Pediatric Research - 2023 -
Screening for Critical Congenital Heart Defects in
Sweden
Katarina Lannering, Kalliopi Kazamia, Gunnar Bergman, Ingegerd Östman-Smith, Petru Liuba, Jenny Alenius Dahlqvist, Anders Elfvin, Mats Mellander
PEDIATRICS - 2023 -
Outbreak of OXA-48-producing Enterobacteriaceae in a neonatal intensive care unit in Western
Sweden
Erika Tång Hallbäck, Anna Johnning, Sofia Myhrman, Marie Studahl, Elisabet Hentz, Anders Elfvin, Ingegerd Adlerberth
European Journal of Clinical Microbiology and Infectious Diseases - 2023 -
Stabilisation and resuscitation with intact cord circulation is feasible using a wide variety of approaches; a scoping
review
Vesta Seyed Alikhani, L. Thies-Lagergren, J. Svedenkrans, Anders Elfvin, J. Bolk, O. Andersson
Acta Paediatrica - 2023 -
Outcome of infants with necrotising enterocolitis at Charlotte Maxeke Johannesburg Academic Hospital, South
Africa
M. Selse, R. T. Saggers, Elisabet Hentz, Anders Elfvin, D. E. Ballot
South African Journal of Child Health - 2023 -
Bone mass and biomarkers in young women with anorexia nervosa: a prospective 3-year follow-up
study
Anna Svedlund, Cecilia Pettersson, Bojan Tubić, Lars Ellegård, Anders Elfvin, P. Magnusson, Diana Swolin-Eide
Journal of Bone and Mineral Metabolism - 2022 -
The Significance of the FTO Gene for Weight and Body Composition in Swedish Women With Severe Anorexia Nervosa During Intensive Nutrition
Therapy
Anna Svedlund, Bojan Tubić, Anders Elfvin, P. Magnusson, Diana Swolin-Eide
Journal of the American College of Nutrition - 2022 -
Neonatal outcomes associated with mode of subsequent birth after a previous caesarean section in a first pregnancy: A Swedish population-based register study between 1999 and
2015
Anna Dencker, Ida Lyckestam Thelin, Valerie Smith, Ingela Lundgren, Christina Nilsson, Huiqi Li, Lars Ladfors, Anders Elfvin
BMJ Paediatrics Open - 2022 -
Virulence, phenotype and genotype characteristics of invasive group B Streptococcus isolates obtained from Swedish pregnant women and
neonates.
Emily M Huebner, Margrét Johansson Gudjónsdóttir, Matthew B Dacanay, Shayla Nguyen, Alyssa Brokaw, Kavita Sharma, Anders Elfvin, Elisabet Hentz, Ysabella Raceli Rivera, Nicole Burd, Megana Shivakumar, Brahm Coler, Miranda Li, Amanda Li, Jeff Munson, Austyn Orvis, Michelle Coleman, Bo Jacobsson, Lakshmi Rajagopal, Kristina M. Adams Waldorf
Annals of clinical microbiology and antimicrobials - 2022 -
Working conditions for hospital-based maternity and neonatal health care workers during extraordinary situations-A pre-/post COVID-19 pandemic analysis and lessons
learned
Magnus Åkerström, Ylva Carlsson, Verena Sengpiel, M. Veje, Anders Elfvin, Ingibjörg H Jonsdottir, Alessio Degl'Innocenti, Linda Åhlström, Helle Wijk, Karolina Linden
Sexual & Reproductive HealthCare - 2022 -
Confirmed reinfection with SARS-CoV-2 during a pregnancy: A case
report.
Verena Sengpiel, Ylva Carlsson, Jan-Åke Liljeqvist, Anders Elfvin, Ing-Marie Fyhr, Anna Lundgren, Kristina Nyström, Mats Bemark, Magnus Gisslén, Johan Ringlander
Clinical case reports - 2022 -
Factors influencing survival and short-term outcomes of very low birth weight infants in a tertiary hospital in
Johannesburg
Kristin Ingemyr, Anders Elfvin, Elisabet Hentz, R. T. Saggers, D. E. Ballot
Frontiers in Pediatrics - 2022 -
Impaired renal clearance among Swedish adolescents born
preterm
Carin Skogastierna, Anders Elfvin, Sverker Hansson, P. Magnusson, Diana Swolin-Eide
Acta Paediatrica - 2022 -
Working conditions for hospital-based maternity and neonatal health care workers during extraordinary situations – a pre/post COVID-19 pandemic analysis and lessons
learned
Magnus Åkerström, Ylva Carlsson, Verena Sengpiel, Malin Veje, Anders Elfvin, Ingibjörg H Jonsdottir, Alessio Degl'Innocenti, Linda Åhlström, Helle Wijk, Karolina Linden
NJF Congress Helsinki - 2022 -
Maternal Dietary Selenium Intake during Pregnancy and Neonatal Outcomes in the Norwegian Mother, Father, and Child Cohort
Study.
Dominika Modzelewska, Pol Solé Navais, Anne Lise Brantsæter, Christopher Flatley, Anders Elfvin, Helle Margrete Meltzer, Verena Sengpiel, Malin Barman, Bo Jacobsson
Nutrients - 2021 -
Late-onset Neonatal Infections 1997 to 2017 Within a Cohort in Western Sweden-The Last 21 Years of a 43-Year
Surveillance.
Margrét Johansson Gudjónsdóttir, Elisabet Hentz, Ingegerd Adlerberth, Ingemar Tessin, Birger Trollfors, Anders Elfvin
The Pediatric infectious disease journal - 2021 -
Effect of Enteral Lipid Supplement on Severe Retinopathy of Prematurity A Randomized Clinical
Trial
Ann Hellström, Anders K. Nilsson, D. Wackernagel, Aldina Pivodic, M. Vanpee, Ulrika Sjöbom, Gunnel Hellgren, B. Hallberg, M. Domellof, Susanna Klevebro, William Hellström, Mats Andersson, A. M. Lund, Chatarina Löfqvist, Anders Elfvin, Karin Sävman, I. Hansen-Pupp, Anna-Lena Hård, L. E. H. Smith, D. Ley
JAMA Pediatrics - 2021 -
Dramatic changes in blood protein levels during the first week of life in extremely preterm
infants
W. Zhong, H. Danielsson, A. Tebani, M. J. Karlsson, Anders Elfvin, Gunnel Hellgren, N. Brusselaers, P. Brodin, Ann Hellström, L. Fagerberg, M. Uhlen
Pediatric Research - 2021 -
The effects of exposure to HIV in neonates at a referral hospital in South
Africa
Helena Mellqvist, R. T. Saggers, Anders Elfvin, Elisabet Hentz, D. E. Ballot
Bmc Pediatrics - 2021 -
Nordic study on human milk fortification in extremely preterm infants: a randomised controlled trial-the N-forte
trial.
Georg Bach Jensen, Fredrik Ahlsson, Magnus Domellöf, Anders Elfvin, Lars Naver, Thomas Abrahamsson
BMJ open - 2021 -
Glycemic, maternal and neonatal outcomes in women with type 1 diabetes using continuous glucose monitoring during pregnancy - pump vs multiple daily injections, a secondary analysis of an observational cohort
study.
Karin Kjölhede, Kerstin Berntorp, Karl Kristensen, Anastasia Katsarou, Nael Shaat, Nana Wiberg, Filip K Knop, Lars Kristensen, Annika Dotevall, Anders Elfvin, Ulrika Sandgren, Verena Sengpiel, Linda Englund-Ögge
Acta obstetricia et gynecologica Scandinavica - 2021 -
Low false-positive rate of perfusion index as a screening tool for neonatal aortic
coarctation
Katarina Lannering, Anders Elfvin, Mats Mellander
Acta Paediatrica, International Journal of Paediatrics - 2021 -
Reduced antibiotic use in extremely preterm infants with an antimicrobial stewardship
intervention
Lars Gustavsson, Simon Lindquist, Anders Elfvin, Elisabet Hentz, Marie Studahl
BMJ paediatrics open - 2020 -
C-reactive protein- and clinical symptoms-guided strategy in term neonates with early-onset sepsis reduced antibiotic use and hospital stay: a quality improvement
initiative.
Johan Gyllensvärd, Fredrik Ingemansson, Elisabet Hentz, Marie Studahl, Anders Elfvin
BMC pediatrics - 2020 -
Low risk of necrotising enterocolitis in enterally fed neonates with critical heart disease: An observational
study
Kajsa Nordenström, Katarina Lannering, Mats Mellander, Anders Elfvin
Archives of Disease in Childhood: Fetal and Neonatal Edition - 2020 -
Increased risk of rickets but not fractures during childhood and adolescence following necrotizing enterocolitis among children born preterm in
Sweden
Amanda Magnusson, M. Ahle, R. E. Andersson, Diana Swolin-Eide, Anders Elfvin
Pediatric Research - 2019 -
Secular trends of birthweight in boys from 1950 to
2010
Jimmy Célind, M. Hedlund, Maria Bygdell, Arvid Sondén, Anders Elfvin, Jenny Kindblom
Pediatrics and Neonatology - 2019 -
Continuous glucose monitoring in pregnant women with type 1 diabetes: an observational cohort study of 186
pregnancies
K. Kristensen, Linda Englund-Ögge, Verena Sengpiel, Karin Kjölhede, Annika Dotevall, Anders Elfvin, F. K. Knop, N. Wiberg, A. Katsarou, N. Shaat, L. Kristensen, K. Berntorp
Diabetologia - 2019 -
Validation of the diagnosis of necrotising enterocolitis in a Swedish population-based observational
study.
Pontus Challis, Linn Larsson, Elisabeth Stoltz Sjöström, Fredrik Serenius, Magnus Domellöf, Anders Elfvin
Acta paediatrica (Oslo, Norway : 1992) - 2019 -
Caffeine exposure during pregnancy, small for gestational age birth and neonatal outcome - results from the Norwegian Mother and Child Cohort
Study.
Dominika Modzelewska, Rino Bellocco, Anders Elfvin, Anne Lise Brantsæter, Helle Margrete Meltzer, Bo Jacobsson, Verena Sengpiel
BMC pregnancy and childbirth - 2019 -
Born a few weeks too early; does it
matter?
Anna Bonnevier, Lars Björklund, Anders Elfvin, Stellan Håkansson, Maria Altman
Läkartidningen - 2019 -
Changes in incidence and etiology of early-onset neonatal infections 1997-2017 - a retrospective cohort study in western
Sweden.
Margrét Johansson Gudjónsdóttir, Anders Elfvin, Elisabet Hentz, Ingegerd Adlerberth, Ingemar Tessin, Birger Trollfors
BMC pediatrics - 2019 -
Intestinal failure after necrotising enterocolitis: incidence and risk factors in a Swedish population-based longitudinal
study.
Tomas Sjoberg Bexelius, Margareta Ahle, Anders Elfvin, Oscar Björling, Jonas F Ludvigsson, Roland E Andersson
BMJ paediatrics open - 2018 -
Maternal caffeine intake during pregnancy and childhood growth and overweight: results from a large Norwegian prospective observational cohort
study.
Eleni Papadopoulou, Jérémie Botton, Anne-Lise Brantsæter, Margaretha Haugen, Jan Alexander, Helle Margrete Meltzer, Jonas Bacelis, Anders Elfvin, Bo Jacobsson, Verena Sengpiel
BMJ open - 2018 -
The effect of twin-to-twin delivery time intervals on neonatal outcome for second
twins.
Linnéa Lindroos, Anders Elfvin, Lars Ladfors, Ulla-Britt Wennerholm
BMC pregnancy and childbirth - 2018 -
Maternal, fetal and perinatal factors associated with necrotizing enterocolitis in Sweden. A national case-control
study
M. Ahle, P. Drott, Anders Elfvin, R. E. Andersson
Plos One - 2018 -
Population-based study showed that necrotising enterocolitis occurred in space-time clusters with a decreasing secular trend in
Sweden.
Amanda Magnusson, Margareta Ahle, Diana Swolin-Eide, Anders Elfvin, Roland E Andersson
Acta paediatrica - 2017 -
Very low birth weight infants face an increased risk of bloodstream infections following the removal of umbilical
catheters.
Simon Lindquist, Elisabet Hentz, Ingemar Tessin, Anders Elfvin
Acta paediatrica - 2016 -
Immunological and Inflammatory Response After Antenatal Supplementation with Lactobacillus Rhamnosus in Low-Risk Pregnant
Women
Bo Jacobsson, Verena Sengpiel, Staffan Nilsson, Maria Hallingström, Anders Elfvin, A. L. Brantsaeter, Masha Nordquist, R. Myhre, Teresa Cobo
63rd Annual Scientific Meeting of the Society-for-Reproductive-Investigation. 16-19 mars, 2016, Location: Montreal, Canada. Reproductive Sciences - 2016 -
Serotypes of group B streptococci in western Sweden and comparison with serotypes in two previous studies starting from
1988.
Margrét Johansson Gudjónsdóttir, Elisabet Hentz, Stefan Berg, Erik Backhaus, Anders Elfvin, Samir Kawash, Birger Trollfors
BMC infectious diseases - 2015 -
Low birth weight, gestational age, need for surgical intervention and gram-negative bacteraemia predict intestinal failure following necrotising
enterocolitis.
Anders Elfvin, Elsa Dinsdale, Paul W Wales, Aideen M Moore
Acta paediatrica (Oslo, Norway : 1992) - 2015 -
Oxidative and nitrosative stress enzymes in relation to nitrotyrosine in Helicobacter pylori -infected
humans
Anders Elfvin, Anders Edebo, Peter Hallersund, Anna Casselbrant, Lars Fändriks
World Journal of Gastrointestinal Pathophysiology - 2014 -
Increased incidence of intestinal failure after necrotizing
enterocolitis.
Amanda Magnusson, Diana Swolin-Eide, Anders Elfvin
Pediatric Academic Societies and Asian Society for Pediatric Research Joint Meeting. Vancouver 3-6 maj 2014. Congressbook publ 4105.95. - 2014 -
Abdominal pathology requiring laparotomy in very preterm infants is associated with need for surgical closure of patent ductus
arteriosus.
Sara Röjås, Helena Borg, Mats Edenholm, Kenneth Sandberg, Anders Elfvin
Journal of pediatric surgery - 2011 -
Breastfeeding in women with type 1 diabetes: exploration of predictive
factors.
Carina Sparud Lundin, Margareta Wennergren, Anders Elfvin, Marie Berg
Diabetes care - 2011 -
Temporary percutaneous and permanent gastric electrical stimulation in children younger than 3 years with chronic
vomiting.
Anders Elfvin, Gunnar Göthberg, Hans Lönroth, Robert Saalman, Hasse Abrahamsson
Journal of pediatric surgery - 2011 -
Temporary percutaneous gastric electrical stimulation: a novel technique tested in patients with non-established indications for gastric electrical
stimulation.
Stina Andersson, Gisela Ringström, Anders Elfvin, Magnus Simrén, Hans Lönroth, Hasse Abrahamsson
Digestion - 2011 -
The expression of renin-angiotensin system components in the human gastric
mucosa.
Peter Hallersund, Anders Elfvin, Herbert F Helander, Lars Fändriks
Journal of the renin-angiotensin-aldosterone system : JRAAS - 2011 -
Angiotensin II receptor expression and relation to Helicobacter pylori-infection in the stomach of the Mongolian
gerbil.
Peter Hallersund, Herbert F Helander, Anna Casselbrant, Anders Edebo, Lars Fändriks, Anders Elfvin
BMC gastroenterology - 2010 -
A slow caloric satiety drinking test in patients with temporary and permanent gastric electrical
stimulation.
Stina Andersson, Anders Elfvin, Gisela Ringström, Hans Lönroth, Hasse Abrahamsson, Magnus Simrén
European journal of gastroenterology & hepatology - 2010 -
CCL28 is increased in human Helicobacter pylori induced gastritis and mediates recruitment of gastric IgA-secreting
cells.
Malin Hansson, Michael Hermansson, Helena Svensson, Anders Elfvin, Lars-Erik Hansson, Erik Johnsson, Åsa Sjöling, Marianne Quiding-Järbrink
Infection and Immunity - 2008 -
Percutaneous implantation of gastric electrodes - a novel technique applied in animals and in
patients
Anders Elfvin, S. Andersson, Hasse Abrahamsson, Anders Edebo, Magnus Simrén, Hans Lönroth
Neurogastroenterology and motility - 2007 -
Quantitative measurement of nitric oxide and hydrogen peroxide in Helicobacter pylori-infected Mongolian gerbils in
vivo
Anders Elfvin, Anders Edebo, Ingrid Bölin, Lars Fändriks
Scandinavian Journal of Gastroenterology - 2007 -
Helicobacter pylori associated effects on inflammatory radical formation and angiotensin II receptors in the
stomach
Anders Elfvin
2007 -
Gastric electrical stimulation for intractable vomiting in patients with chronic intestinal
pseudoobstruction
S. Andersson, Hans Lönroth, Magnus Simrén, G. Ringstrom, Anders Elfvin, Hasse Abrahamsson
Neurogastroenterology and motility - 2006 -
Gastric expression of inducible nitric oxide synthase and myeloperoxidase in relation to nitrotyrosine in Helicobacter pylori-infected Mongolian
gerbils.
Anders Elfvin, Ingrid Bölin, Hans Lönroth, Lars Fändriks
Scandinavian journal of gastroenterology - 2006 -
Helicobacter pylori induces gastritis and intestinal metaplasia but no gastric adenocarcinoma in Mongolian
gerbils.
Anders Elfvin, Ingrid Bölin, Charlotte Von Bothmer, Manfred Stolte, Hidenobu Watanabe, Lars Fändriks, Michael Vieth
Scandinavian journal of gastroenterology - 2005