University of Gothenburg
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Anders Elfvin

UNIVERSITETSLEKTOR, ADJUNGERAD

Department of
Pediatrics
Mail
anders.elfvin@gu.se

About Anders Elfvin

Summary in english Overall aim is to identify changes over time regarding invasive infections in infancy, to identify patterns in early inflammatory markers and microbial flora related to development of necrotizing enterocolitis (NEC) and sepsis, and to prevent sequelae as intestinal failure and osteopenia in children post NEC

The overall aim is currently addressed in four specific aims:

1. To identify changes in the panorama of bacteria, incidence of disease and mortality of all cases of sepsis and meningitis in new-born infants in the Gothenburg area between the years 1997-2017, compared to the years 1975-1986 and 1987-1996.

2. To in a prospective cohort study identify early patterns in signal proteins such as angiogenetic regulatory proteins, oral- and intestinal flora related to an increased risk of developing NEC and sepsis among preterm infants.

3. To identify differences in the intestinal flora, bone mass and BMI at 4 and 7 years of age in children born preterm with a history of NEC compared to preterm infants not diagnosed with NEC

4. To clarify whether children diagnosed with NEC between the years of 1987-2009 have an increased risk of vitamin-D deficiency, rickets and fractures during childhood compared to children born at the same gestational age without NEC.