University of Gothenburg
University of Gothenburg
  2. Research
  3. Find research
  4. Mechanism of action of Carbapenemases, and development of inhibitors against these

Mechanism of action of Carbapenemases, and development of inhibitors against these

Research project
Active research
Website
Project
description
Project owner
Prof Leif A. Eriksson (PI), Prof Johan Gottfries and Sonali Chavan (PhD student), Dep. of Chemistry and Molecular Biology at GU.
Financier
Swedish Research Council and CARe
Area
Sustainability and
environment
Topic
Pharmaceutical
biochemistry

Short description

In this project we investigate by means of high-level QM/MM-methodology, the mechanism of action of carbapenemases, and in particular KPC-2, towards representative compounds from the different classes of beta-lactam antibiotics to better understand detailed structural and electronic features.

Last modified