Göteborgs universitet
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  4. Mechanism of action of Carbapenemases, and development of inhibitors against these

Mechanism of action of Carbapenemases, and development of inhibitors against these

Research project
Pågående forskning
Webbplats
Project description
Projektägare
Prof Leif A. Eriksson (PI), Prof Johan Gottfries and Sonali Chavan (PhD student), Dep. of Chemistry and Molecular Biology at GU.
Finansiär
Swedish Research Council and CARe
Område
Sustainability and environment
Ämne
Pharmaceutical biochemistry

Kort beskrivning

In this project we investigate by means of high-level QM/MM-methodology, the mechanism of action of carbapenemases, and in particular KPC-2, towards representative compounds from the different classes of beta-lactam antibiotics to better understand detailed structural and electronic features.

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