Department of Psychiatry and
About Erik Smedler
I am a resident physician in psychiatry at Sahlgrenska University Hospital (SU) and researcher at Gothenburg University (GU). Prior to that, I did my MD-PhD at Karolinska Institutet and MSc in engineering physics at the Royal Institute of Technology in Stockholm. My thesis was focused on neural networks and calcium signaling. I did my postdoc in the group of Mikael Landén at GU 2017-2019 and medical internship at SU.
My research is focused on bipolar disorder, with emphasis on neural development. My line of research is on how disturbances in the development of neural networks lead to manifest psychiatric illness, with focus on the calcium channel gene CACNA1C. At the moment, we are developing IPS cell-based models of bipolar patients in conjunction with clinical data from patients.
I am co-supervisor of the PhD students Anniella Isgren and Andreas Göteson as well as main supervisor for the medical students Johanna Kleppe and Sohaib Hattab. During the spring of 2019 supervised the master thesis of Ali Hattabs.
My research is funded by: ALF, Magnus Bergvall's foundation, Åhlén-foundation, Fredrik och Ingrid Thuring's foundation, Göteborgs läkaresällskap, Längmanska Kulturfonden, Märta Lundqvist's foundation, Wilhelm och Martina Lundgrens Vetenskapsfond, SUs foundations och Konrad och Helfrid Johansson's foundation.
Feel free to contact me if you are interested in collaborations or thesis projects. There are continuously openings for both experimental and theoretical projects.
See my papers on Pubmed using: smedler e OR nilsson es
Reporting trigger factors for (hypo)manic episodes in bipolar disorder: association with personality and
Association of CACNA1C polymorphisms with serum BDNF levels in bipolar
CACNA1C polymorphism and brain cortical structure in bipolar
Genes, biomarkers, and clinical features associated with the course of bipolar
Mapping genes for calcium signaling and their associated human genetic
Matthias Hörtenhuber, Enrique M Toledo, Erik Smedler, Ernest Arenas, Seth Malmersjö, Lauri Louhivuori, Per Uhlén
Bioinformatics (Oxford, England) - 2017-01-01
The 1p36 Tumor Suppressor KIF 1B beta Is Required for Calcineurin Activation, Controlling Mitochondrial Fission and
Calcium signaling in neocortical
Per Uhlén, Nicolas Fritz, Erik Smedler, Seth Malmersjö, Shigeaki Kanatani
Developmental neurobiology - 2015-01-01
Network analysis of time-lapse microscopy
Erik Smedler, Seth Malmersjö, Per Uhlén
Frontiers in neural circuits - 2014-01-01
Cathelicidin LL-37 induces time-resolved release of LTB4 and TXA2 by human macrophages and triggers eicosanoid generation in
Min Wan, Oliver Soehnlein, Xiao Tang, Anne M van der Does, Erik Smedler, Per Uhlén, Lennart Lindbom, Birgitta Agerberth, Jesper Z Haeggström
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2014-01-01
Frequency decoding of calcium
Erik Smedler, Per Uhlén
Biochimica et biophysica acta - 2014-01-01
Small-world networks of spontaneous Ca(2+)
Seth Malmersjö, Paola Rebellato, Erik Smedler, Per Uhlén
Communicative & integrative biology - 2013-01-01
Neural progenitors organize in small-world networks to promote cell
Seth Malmersjö, Paola Rebellato, Erik Smedler, Henrike Planert, Shigeaki Kanatani, Isabel Liste, Evanthia Nanou, Hampus Sunner, Shaimaa Abdelhady, Songbai Zhang, Michael Andäng, Abdeljabbar El Manira, Gilad Silberberg, Ernest Arenas, Per Uhlén
Proceedings of the National Academy of Sciences of the United States of America - 2013-01-01
Small molecule screening platform for assessment of cardiovascular toxicity on adult zebrafish
Satish Srinivas Kitambi, Erik Smedler, Petra Sekyrova, Cristian Ibarra, Gilbert Nyah Tekeoh, Michael Andäng, Patrik Ernfors, Per Uhlén
BMC physiology - 2012-01-01