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- Sergio Trillo Muyo
Sergio Trillo Muyo
Researcher
Department of Medical Biochemistry and Cell biology-
EatA mediated degradation of intestinal mucus is species-specific and driven by MUC2 structural
features
Sergio Trillo Muyo, Brendan Dolan, Frida Svensson, Tim J. Vickers, Liisa Arike, Maria Jose Garcia Bonete, Jenny Gustafsson, Mathias I. Nielsen, Hans H. Wandall, James M. Fleckenstein, Gunnar C Hansson, Sjoerd van Der Post
Nature Communications - 2026 -
Structure of the MUC5AC VWD3 assembly responsible for the formation of net-like mucin
polymers
Sergio Trillo-Muyo, Anna Ermund, Gunnar C. Hansson
EMBO REPORTS - 2025 -
The structure of FCGBP is formed as a disulfide-mediated homodimer between its C-terminal
domains
Erik Ehrencrona, Pablo Gallego, Sergio Trillo-Muyo, Maria-Jose Garcia-Bonete, Christian V Recktenwald, Gunnar C. Hansson, Malin E V Johansson
FEBS JOURNAL - 2025 -
BPP43_05035 is a Brachyspira pilosicoli cell surface adhesin that weakens the integrity of the epithelial barrier during
infection
Anandi Rajan, Pablo Gallego, Brendan Dolan, Piyush Patel, Chinmay Dwibedi, Ana S. Luis, Sergio Trillo-Muyo, Liisa Arike, Sjoerd van der Post, Magnus Simrén, Thaher Pelaseyed
GUT MICROBES - 2024 -
The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based
cross-linking
Christian V Recktenwald, Göran Karlsson, Maria-Jose Garcia-Bonete, Gergely Katona, Maja Jensen, Richard Lymer, Malin Bäckström, Malin E V Johansson, Gunnar C. Hansson, Sergio Trillo-Muyo
Cell Reports - 2024 -
The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming
mucins
Pablo Gallego, Maria-Jose Garcia-Bonete, Sergio Trillo-Muyo, Christian V Recktenwald, Malin E V Johansson, Gunnar C. Hansson
Nature communications - 2023 -
Structural mechanism of signal transduction in a phytochrome histidine
kinase
Weixiao Yuan Wahlgren, Elin Claesson, Iida Tuure, Sergio Trillo-Muyo, Szabolcs Bódizs, Janne A. Ihalainen, Heikki Takala, Sebastian Westenhoff
Nature Communications - 2022 -
The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide
bonds
Erik Ehrencrona, Sjoerd van der Post, Pablo Gallego, Christian V Recktenwald, Ana Rodriguez-Piñeiro, Maria-Jose Garcia-Bonete, Sergio Trillo-Muyo, Malin Bäckström, Gunnar C. Hansson, Malin E V Johansson
Journal of Biological Chemistry - 2021 -
Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b
mucin
Dalia Fakih, Ana Rodriguez-Piñeiro, Sergio Trillo-Muyo, C. M. Evans, Anna Ermund, Gunnar C. Hansson
American Journal of Physiology-Lung Cellular and Molecular Physiology - 2020 -
Granule-stored MUC5B mucins are packed by the non-covalent formation of N-terminal head-to-head
tetramers
Sergio Trillo-Muyo, Harriet E. Nilsson, Christian V Recktenwald, Anna Ermund, C. Ridley, Lauren N Meiss, A. Bahr, N. Klymiuk, Jeffrey J. Wine, P. J. B. Koeck, D. J. Thornton, H. Hebert, Gunnar C. Hansson
Journal of Biological Chemistry - 2018 -
Assembly, Release, and Transport of Airway Mucins in Pigs and
Humans
Anna Ermund, Sergio Trillo-Muyo, Gunnar C. Hansson
Annals of the American Thoracic Society - 2018 -
The normal trachea is cleaned by MUC5B mucin bundles from the submucosal glands coated with the MUC5AC
mucin
Anna Ermund, Lauren N Meiss, Ana María Rodríguez-Piñeiro, A. Bahr, Harriet E. Nilsson, Sergio Trillo-Muyo, C. Ridley, D. J. Thornton, J. J. Wine, H. Hebert, N. Klymiuk, Gunnar C. Hansson
Biochemical and Biophysical Research Communications - BBRC - 2017