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CARe scientists have developed a fast and cost-efficient method to screen for novel genes which effect antibiotic resistance transmission by conjugation.

A novel experimental framework to screen for conjugation based horizontal transmission of antibiotic resistance between >60,000 pairs of cell populations in parallel have been developed. The research team identified >50 novel factors, all of which diminish antibiotic resistance transmission. The new framework holds great potential for exhaustive disclosing of candidate targets for helper drugs that delay resistance development in patients and societies and improves the longevity of current and future antibiotics.

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