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- Ulf Lerner
Ulf Lerner
Seniorforskare
Avd för invärtesmedicin och klinisk nutritionOm Ulf Lerner
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Vitamin A - discovery, metabolism, receptor signaling and effects on bone mass and fracture
susceptibility
Ulf H Lerner
Frontiers in Endocrinology - 2024 -
Focal Staphylococcus Aureus Septic Arthritis Elicits Age and TLR2-Dependent Periarticular Bone
Loss.
Michelle Schultz, Zhicheng Hu, Meghshree Deshmukh, Petra Henning, Ulf H Lerner, Majd Mohammad, Tao Jin
Journal of Inflammation Research - 2024 -
GREM2 inactivation increases trabecular bone mass in
mice
Karin H. Nilsson, Petra Henning, Jianyao Wu, Klara Sjögren, Ulf H Lerner, Claes Ohlsson, Sofia Moverare-Skrtic
Scientific Reports - 2024 -
Vitamin A enhanced periosteal osteoclastogenesis is associated with increased number of tissue-derived macrophages/osteoclast
progenitors
Petra Henning, Anna Westerlund, Karin Horkeby, Vikte Lionikaite, Karin H. Nilsson, Sofia Movérare-Skrtic, H. Herschel Conaway, Ulf H Lerner
Journal of Biological Chemistry - 2024 -
The PerioGene North Study Uncovers Serum Proteins Related to
Periodontitis
M. Wanman, S. Betner, A. Esberg, C. K. Holm, C. Isehed, A. Holmlund, P. Palmqvist, A. Lovgren, S. Lindquist, L. Hanstrom, Ulf H Lerner, E. Kindstedt, P. Lundberg
Journal of Dental Research - 2024 -
Toll-like receptor-2 induced inflammation causes local bone formation and activates canonical Wnt
signaling.
Petra Henning, Ali Kassem, Anna Westerlund, Pernilla Lundberg, Cecilia Engdahl, Vikte Lionikaite, Pernilla Wikström, Jianyao Wu, Lei Li, Catharina Lindholm, Pedro P C de Souza, Sofia Movérare-Skrtic, Ulf H Lerner
Frontiers in immunology - 2024 -
The novel cytotoxic polybisphosphonate osteodex decreases bone resorption by enhancing cell death of mature osteoclasts without affecting osteoclastogenesis of RANKL-stimulated mouse bone marrow
macrophages
Petra Henning, Anna Westerlund, Sofia Moverare-Skrtic, Catharina Lindholm, Marcela Marquez-Mendez, Sten Nilsson, Anders R. Holmberg, Ulf H Lerner
INVESTIGATIONAL NEW DRUGS - 2024 -
Vitamin A – a scoping review for Nordic nutrition Recommendations
2023
Thomas Olsen, Ulf H Lerner
Food and Nutrition Research - 2023 -
B4GALNT3 regulates glycosylation of sclerostin and bone
mass
Sofia Moverare-Skrtic, J. Voelkl, Karin H. Nilsson, Maria Nethander, T. T. D. Luong, I. Alesutan, Lei Li, Jianyao Wu, Karin L Horkeby, Marie K Lagerquist, A. Koskela, J. Tuukkanen, J. H. Tobias, Ulf H Lerner, Petra Henning, Claes Ohlsson
eBioMedicine - 2023 -
Osteoprotective effect by interleukin-4 (IL-4) on lipoprotein-induced
periodontitis
Jorge F. Lima Teixeira, Petra Henning, Fernando A. Cintra Magalhães, Glaucia Coletto-Nunes, Thais Floriano-Marcelino, Anna Westerlund, Sofia Movérare-Skrtic, Guilherme J.P.L. Oliveira, Ulf H Lerner, Pedro Paulo C. Souza
Cytokine - 2023 -
An atlas of genetic determinants of forearm
fracture.
Maria Nethander, Sofia Movérare-Skrtic, Anders Kämpe, Eivind Coward, Ene Reimann, Louise Grahnemo, Éva Borbély, Zsuzsanna Helyes, Thomas Funck-Brentano, Martine Cohen-Solal, Juha Tuukkanen, Antti Koskela, Jianyao Wu, Lei Li, Tianyuan Lu, Maiken E Gabrielsen, Reedik Mägi, Mari Hoff, Ulf H Lerner, Petra Henning, Henrik Ullum, Christian Erikstrup, Søren Brunak, Arnulf Langhammer, Tiinamaija Tuomi, Asmundur Oddsson, Kari Stefansson, Ulrika Pettersson-Kymmer, Sisse Rye Ostrowski, Ole Birger Vesterager Pedersen, Unnur Styrkarsdottir, Outi Mäkitie, Kristian Hveem, J Brent Richards, Claes Ohlsson
Nature genetics - 2023 -
Anemia is associated with increased risk of non-vertebral osteoporotic fractures in elderly men: the MrOS Sweden
cohort
Hallgerdur Lind Kristjansdottir, Dan Mellström, Peter Johansson, M. Karlsson, Liesbeth Vandenput, Mattias Lorentzon, Hans Herlitz, Claes Ohlsson, Ulf H Lerner, Catharina Lewerin
Archives of Osteoporosis - 2022 -
Phytocystatin CsinCPI-2 Reduces Osteoclastogenesis and Alveolar Bone
Loss
N. D. Leguizamon, R. S. de Molo, G. Coletto-Nunes, A. V. B. Nogueira, S. V. Rocha, D. M. Neo-Justino, A. Soares-Costa, P. S. Cerri, Ulf H Lerner, P. P. C. Souza, J. A. Cirelli
Journal of Dental Research - 2022 -
Stimulation of osteoclast formation and bone resorption by glucocorticoids: Synergistic interactions with the calcium regulating hormones parathyroid hormone and 1,25(OH)<inf>2</inf>-vitamin
D3
Petra Henning, H. Herschel Conaway, Ulf H Lerner
Vitamins and Hormones Vol 120 Parathyroid Hormone - 2022 -
Estradiol and RSPO3 regulate vertebral trabecular bone mass independent of each
other
Karin H. Nilsson, Jianyao Wu, Karin L. Gustafsson, Maha El Shahawy, A. Koskela, J. Tuukkanen, J. Tuckermann, Petra Henning, Ulf H Lerner, Claes Ohlsson, Sofia Movérare-Skrtic
American journal of physiology. Endocrinology and metabolism - 2022 -
Stimulation of Osteoclast Formation by Oncostatin M and the Role of WNT16 as a Negative Feedback
Regulator
P. P. C. de Souza, Petra Henning, Ulf H Lerner
International Journal of Molecular Sciences - 2022 -
RSPO3 is important for trabecular bone and fracture risk in mice and
humans
Karin H. Nilsson, Petra Henning, Maha El Shahawy, Maria Nethander, T. L. Andersen, C. Ejersted, Jianyao Wu, Karin L. Gustafsson, A. Koskela, J. Tuukkanen, P. P. C. Souza, J. Tuckermann, Mattias Lorentzon, Linda Engström Ruud, T. Lehtimaki, J. H. Tobias, S. R. Zhou, Ulf H Lerner, J. B. Richards, Sofia Moverare-Skrtic, Claes Ohlsson
Nature Communications - 2021 -
WNT16 is Robustly Increased by Oncostatin M in Mouse Calvarial Osteoblasts and Acts as a Negative Feedback Regulator of Osteoclast Formation Induced by Oncostatin
M
Petra Henning, Sofia Moverare-Skrtic, Anna Westerlund, P. P. C. de Souza, T. Floriano-Marcelino, Karin H. Nilsson, Maha El Shahawy, Claes Ohlsson, Ulf H Lerner
Journal of Inflammation Research - 2021 -
Immunoglobulin G complexes without sialic acids enhance osteoclastogenesis but do not affect arthritis-mediated bone
loss.
Edina Sehic, Anna Westerlund, Marie K Lagerquist, Ulf H Lerner, Hans Carlsten, Petra Henning, Cecilia Engdahl
Scandinavian journal of immunology - 2021 -
Osteocyte- and late osteoblast-derived NOTUM reduces cortical bone mass in
mice
Karin H. Nilsson, Petra Henning, Maha El Shahawy, Jianyao Wu, A. Koskela, J. Tuukkanen, C. Perret, Ulf H Lerner, Claes Ohlsson, Sofia Moverare-Skrtic
American Journal of Physiology-Endocrinology and Metabolism - 2021 -
High platelet count is associated with low bone mineral density: The MrOS Sweden
cohort.
Hallgerdur Lind Kristjansdottir, Dan Mellström, P. Johansson, M. Karlsson, Liesbeth Vandenput, Mattias Lorentzon, Hans Herlitz, Claes Ohlsson, Ulf H Lerner, Catharina Lewerin
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 2021 -
An ARHGAP25 variant links aberrant Rac1 function to early-onset skeletal
fragility
R. E. Makitie, Petra Henning, Y. Jiu, A. Kampe, K. Kogan, A. Costantini, V. V. Valimaki, C. Medina-Gomez, M. Pekkinen, I. B. Salusky, C. Schalin-Jantti, M. K. Haanpaa, F. Rivadeneira, J. H. D. Bassett, G. R. Williams, Ulf H Lerner, R. C. Pereira, P. Lappalainen, O. Makitie
JBMR Plus - 2021 -
High Plasma Erythropoietin Predicts Incident Fractures in Elderly Men with Normal Renal Function: The MrOS Sweden
Cohort.
Hallgerdur Lind Kristjansdottir, Catharina Lewerin, Ulf H Lerner, Hans Herlitz, Peter Johansson, Helena Johansson, Magnus Karlsson, Mattias Lorentzon, Claes Ohlsson, Östen Ljunggren, Dan Mellström
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2020 -
Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and
Fractures
J. Zheng, W. Maerz, I. Gergei, M. Kleber, C. Drechsler, C. Wanner, V. Brandenburg, S. Reppe, K. M. Gautvik, C. Medina-Gomez, E. Shevroja, A. Gilly, Y. C. Park, G. Dedoussis, E. Zeggini, Mattias Lorentzon, Petra Henning, Ulf H Lerner, Karin H. Nilsson, Sofia Moverare-Skrtic, D. Baird, B. Elsworth, L. Falk, A. Groom, T. D. Capellini, E. Grundberg, Maria Nethander, Claes Ohlsson, G. D. Smith, J. H. Tobias
Journal of Bone and Mineral Research - 2019 -
Vitamin A decreases the anabolic bone response to mechanical loading by suppressing bone
formation
Vikte Lionikaite, Petra Henning, Christina Drevinge, Furqan A. Shah, Anders Palmquist, P. Wikström, Sara H Windahl, Ulf H Lerner
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2019 -
Activation of Toll-like receptor 2 induces B1 and B2 kinin receptors in human gingival fibroblasts and in mouse
gingiva
P. P. C. Souza, P. Lundberg, I. Lundgren, F. A. C. Magalhaes, C. M. Costa-Neto, Ulf H Lerner
Scientific Reports - 2019 -
Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in
humans
Sofia Moverare-Skrtic, Karin H. Nilsson, Petra Henning, Thomas Funck-Brentano, Maria Nethander, F. Rivadeneira, G. C. Nunes, A. Koskela, J. Tuukkanen, J. Tuckermann, C. Perret, P. P. C. Souza, Ulf H Lerner, Claes Ohlsson
Faseb Journal - 2019 -
The critical interplay between bone resorbing and bone forming
cells
Ulf H Lerner, E. Kindstedt, P. Lundberg
Journal of Clinical Periodontology - 2019 -
Osteoporosis and skeletal dysplasia caused by pathogenic variants in
SGMS2
M. Pekkinen, P. A. Terhal, L. D. Botto, Petra Henning, R. E. Makitie, P. Roschger, A. Jain, M. Kol, M. A. Kjellberg, E. P. Paschalis, K. van Lassen, M. Murray, P. Bayrak-Toydemir, Maria K Magnusson, J. Jans, M. Kausar, J. C. Carey, P. Somerharju, Ulf H Lerner, V. M. Olkkonen, K. Klaushofer, J. C. M. Holthuis, O. Makitie
Jci Insight - 2019 -
NOTUM inhibition increases endocortical bone formation and bone
strength
Robert Brommage, J. Liu, P. Vogel, F. Mseeh, A. Y. Thompson, D. G. Potter, M. K. Shadoan, G. M. Hansen, S. Jeter-Jones, J. Cui, D. Bright, J. P. Bardenhagen, D. D. Doree, Sofia Moverare-Skrtic, Karin H. Nilsson, Petra Henning, Ulf H Lerner, Claes Ohlsson, A. T. Sands, J. E. Tarver, D. R. Powell, B. Zambrowicz, Q. Y. Liu
Bone Research - 2019 -
Glucocorticoids employ the monomeric glucocorticoid receptor to potentiate vitamin D3 and parathyroid hormone-induced
osteoclastogenesis.
H Herschel Conaway, Petra Henning, Antia Lie, Jan Tuckermann, Ulf H Lerner
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2019 -
Osteoclasts in Health and
Disease.
Ulf H Lerner
Pediatric endocrinology reviews : PER - 2019 -
Finding a Toll on the Route: The Fate of Osteoclast Progenitors After Toll-Like Receptor
Activation
P. P. C. Souza, Ulf H Lerner
Frontiers in Immunology - 2019 -
Activation of Shc1 allows oncostatin M to induce RANKL and osteoclast formation more effectively than leukemia inhibitory
factor
E. Persson, P. P. C. Souza, T. Floriano-Marcelino, H. H. Conaway, Petra Henning, Ulf H Lerner
Frontiers in Immunology - 2019 -
Porcupine inhibitors impair trabecular and cortical bone mass and strength in
mice
Thomas Funck-Brentano, Karin H. Nilsson, Robert Brommage, Petra Henning, Ulf H Lerner, A. Koskela, J. Tuukkanen, M. Cohen-Solal, Sofia Moverare-Skrtic, Claes Ohlsson
Journal of Endocrinology - 2018 -
WNT16 overexpression partly protects against glucocorticoid-induced bone
loss
Claes Ohlsson, Karin H. Nilsson, Petra Henning, Jianyao Wu, Karin L. Gustafsson, Matti Poutanen, Ulf H Lerner, Sofia Moverare-Skrtic
American Journal of Physiology-Endocrinology and Metabolism - 2018 -
Effects of retinoids on physiologic and inflammatory osteoclastogenesis in
vitro
Vikte Lionikaite, Anna Westerlund, H. H. Conaway, Petra Henning, Ulf H Lerner
Journal of leukocyte biology - 2018 -
Clinically relevant doses of Vitamin A decrease cortical bone mass in
mice
Vikte Lionikaite, Karin L. Gustafsson, Anna Westerlund, Sara H Windahl, A. Koskela, J. Tuukkanen, H. Johansson, Claes Ohlsson, H. Herschel Conaway, Petra Henning, Ulf H Lerner
Journal of Endocrinology - 2018 -
High Serum Serotonin Predicts Increased Risk for Hip Fracture and Nonvertebral Osteoporotic Fractures: The MrOS Sweden
Study.
Hallgerdur Lind Kristjansdottir, Catharina Lewerin, Ulf H Lerner, Ewa Waern, Helena Johansson, Daniel Sundh, Magnus Karlsson, Steve R Cummings, Henrik Zetterberg, Mattias Lorentzon, Claes Ohlsson, Dan Mellström
Journal of Bone and Mineral Research - 2018 -
Antibiotics with Interleukin-15 inhibition reduces joint inflammation and bone erosions but not cartilage destruction in Staphylococcus aureus-induced
arthritis.
Berglind Bergmann, Pernilla Jirholt, Petra Henning, Catharina Lindholm, Claes Ohlsson, Iain B McInnes, Ulf H Lerner, Inger Gjertsson
Infection and immunity - 2018 -
Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult
mice.
Claes Ohlsson, Petra Henning, Karin H. Nilsson, Jianyao Wu, Karin L. Gustafsson, Klara Sjögren, Anna E Törnqvist, Antti Koskela, Fu-Ping Zhang, Marie Lagerquist, Matti Poutanen, Juha Tuukkanen, Ulf H Lerner, Sofia Movérare-Skrtic
The Journal of endocrinology - 2018 -
Bone Cell Activity in Clinical Prostate Cancer Bone Metastasis and Its Inverse Relation to Tumor Cell Androgen Receptor
Activity
A. Nordstrand, E. B. Ylitalo, E. Thysell, E. Jernberg, S. Crnalic, A. Widmark, A. Bergh, Ulf H Lerner, P. Wikstrom
International Journal of Molecular Sciences - 2018 -
The Crucial Role of the WNT System in Bone
Remodelling
D. Grigorie, Ulf H Lerner
Acta Endocrinologica - 2018 -
SNX10 gene mutation leading to osteopetrosis with dysfunctional
osteoclasts
E. L. Stattin, Petra Henning, J. Klar, E. McDermott, C. Stecksen-Blicks, P. E. Sandstrom, T. G. Kellgren, P. Ryden, G. Hallmans, T. Lonnerholm, A. Ameur, M. H. Helfrich, F. P. Coxon, N. Dahl, J. Wikstrom, Ulf H Lerner
Scientific Reports - 2017 -
Inhibition of the insulin-like growth factor-1 receptor potentiates acute effects of castration in a rat model for prostate cancer growth in
bone
A. Nordstrand, S. H. Bergstrom, E. Thysell, E. Bovinder-Ylitalo, Ulf H Lerner, A. Widmark, A. Bergh, P. Wikstrom
Clinical & Experimental Metastasis - 2017 -
Inhibition of lipopolysaccharide-induced osteoclast formation and bone resorption in vitro and in vivo by cysteine proteinase
inhibitors
F. Stralberg, A. Kassem, F. Kasprzykowski, M. Abrahamson, A. Grubb, Catharina Lindholm, Ulf H Lerner
Journal of Leukocyte Biology - 2017 -
Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing
osteoporosis
P. Liu, S. Lee, J. Knoll, A. Rauch, S. Ostermay, J. Luther, N. Malkusch, Ulf H Lerner, M. M. Zaiss, M. Neven, R. Wittig, M. Rauner, J. P. David, P. Bertolino, C. X. Zhang, J. P. Tuckermann
Cell Death and Differentiation - 2017 -
Toll-Like Receptor 2 Stimulation of Osteoblasts Mediates Staphylococcus Aureus Induced Bone Resorption and Osteoclastogenesis through Enhanced
RANKL
A. Kassem, Catharina Lindholm, Ulf H Lerner
Plos One - 2016 -
High plasma osteocalcin is associated with low blood haemoglobin in elderly men: the MrOS Sweden
Study
Catharina Lewerin, Helena Johansson, M. K. Karlsson, Mattias Lorentzon, Ulf H Lerner, Jenny Kindblom, Claes Ohlsson, Ulf Smith, Dan Mellström
Journal of Internal Medicine - 2016 -
Vitaminer och
benhälsa
Ulf H Lerner
Nordisk Nutrition - 2016
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