Marie Lagerquist
Avd-/Sektionschef, bitr, inst
Avd för invärtesmedicin och kliniskOm Marie Lagerquist
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Dietary Progesterone Contributes to Intratissue Levels of Progesterone in Male
Mice
Hannah Colldén, Malin Hagberg Thulin, A. Landin, Karin Horkeby, Marie Lagerquist, Jianyao Wu, Karin H. Nilsson, Louise Grahnemo, Matti Poutanen, H. Ryberg, Liesbeth Vandenput, Claes Ohlsson
Endocrinology - 2023 -
B4GALNT3 regulates glycosylation of sclerostin and bone
mass
Sofia Moverare-Skrtic, J. Voelkl, Karin H. Nilsson, Maria Nethander, T. T. D. Luong, I. Alesutan, Lei Li, Jianyao Wu, Karin L Horkeby, Marie K Lagerquist, A. Koskela, J. Tuukkanen, J. H. Tobias, Ulf H Lerner, Petra Henning, Claes Ohlsson
eBioMedicine - 2023 -
Membrane estrogen receptor alpha signaling modulates the sensitivity to estradiol treatment in a dose- and tissue- dependent
manner
Yiwen Jiang, Karin L Horkeby, Petra Henning, Jianyao Wu, Lina Lawenius, Cecilia Engdahl, Priti Gupta, Sofia Moverare-Skrtic, Karin H. Nilsson, E. Levin, Claes Ohlsson, Marie K Lagerquist
Scientific Reports - 2023 -
Phosphorylation of S122 in ERα is important for the skeletal response to estrogen treatment in male
mice
Karin L Horkeby, Helen H. Farman, Sofia Movérare-Skrtic, Vikte Lionikaite, Jianyao Wu, Petra Henning, Sara H Windahl, Klara Sjögren, Claes Ohlsson, Marie K Lagerquist
Scientific Reports - 2022 -
Physiological levels of estradiol limit murine osteoarthritis
progression
Carmen Corciulo, Julia M. Scheffler, Piotr Humeniuk, Alicia M. del Carpio Pons, Alexandra Stubelius, U. Von Mentzer, Christina Drevinge, Aidan Barrett, Sofia Wüstenhagen, Matti Poutanen, Claes Ohlsson, Marie K Lagerquist, Ulrika Islander
Journal of Endocrinology - 2022 -
Dehydroepiandrosterone Supplementation Results in Varying Tissue-specific Levels of Dihydrotestosterone in Male
Mice
Hannah Colldén, Maria E. Nilsson, A. K. Norlen, A. Landin, S. H. Windahl, Jianyao Wu, Karin L Horkeby, Marie K Lagerquist, H. Ryberg, Matti Poutanen, Liesbeth Vandenput, Claes Ohlsson
Endocrinology - 2022 -
A tissue-specific role of membrane-initiated ERα signaling for the effects of
SERMs
Karin L. Gustafsson, Sofia Movérare-Skrtic, Helen H. Farman, Cecilia Engdahl, Petra Henning, Karin H. Nilsson, Julia M. Scheffler, Edina Sehic, Ulrika Islander, E. Levin, Claes Ohlsson, Marie K Lagerquist
Journal of Endocrinology - 2022 -
ER alpha Signaling in a Subset of CXCL12-Abundant Reticular Cells Regulates Trabecular Bone in
Mice
Julia M. Scheffler, Karin L. Gustafsson, Aidan Barrett, Carmen Corciulo, Christina Drevinge, Alicia M. del Carpio Pons, Piotr Humeniuk, Cecilia Engdahl, J. A. Gustafsson, Claes Ohlsson, Hans Carlsten, Marie K Lagerquist, Ulrika Islander
JBMR Plus - 2022 -
Reduction of Mature B Cells and Immunoglobulins Results in Increased Trabecular
Bone
Marie K Lagerquist, P. Gupta, E. Sehic, Karin L Horkeby, Julia M. Scheffler, Jauqueline Nordqvist, Lina Lawenius, Ulrika Islander, Carmen Corciulo, Petra Henning, Hans Carlsten, Cecilia Engdahl
Jbmr Plus - 2022 -
A tissue-selective estrogen complex as treatment of osteoporosis in experimental
lupus
Jauqueline Nordqvist, Cecilia Engdahl, Julia M. Scheffler, Priti Gupta, Karin L. Gustafsson, Marie K Lagerquist, Hans Carlsten, Ulrika Islander
Lupus - 2022 -
Pulsed administration for physiological estrogen replacement in
mice
Carmen Corciulo, Julia M. Scheffler, Karin L. Gustafsson, Christina Drevinge, Piotr Humeniuk, Alicia M. del Carpio Pons, Matti Poutanen, Claes Ohlsson, Marie K Lagerquist, Ulrika Islander
F1000Research - 2021 -
Acute fat loss does not affect bone
mass
Marie K Lagerquist, Karin L. Gustafsson, Petra Henning, Helen H. Farman, Jianyao Wu, Klara Sjögren, A. Koskela, J. Tuukkanen, Claes Ohlsson, Ingrid Wernstedt Asterholm, Louise Grahnemo
Scientific Reports - 2021 -
Immunoglobulin G complexes without sialic acids enhance osteoclastogenesis but do not affect arthritis-mediated bone
loss.
Edina Sehic, Anna Westerlund, Marie K Lagerquist, Ulf H Lerner, Hans Carlsten, Petra Henning, Cecilia Engdahl
Scandinavian journal of immunology - 2021 -
Mild stimulatory effect of a probiotic mix on bone mass when treatment is initiated 1.5 weeks after ovariectomy in
mice
Claes Ohlsson, Lina Lawenius, Annica Andersson, Karin L. Gustafsson, Jianyao Wu, Marie Lagerquist, Sofia Moverare-Skrtic, Ulrika Islander, Klara Sjögren
American Journal of Physiology-Endocrinology and Metabolism - 2021 -
Arginine site 264 in murine estrogen receptor alpha is dispensable for the regulation of the
skeleton.
Karin L. Gustafsson, Helen H. Farman, Karin H. Nilsson, Petra Henning, Sofia Movérare-Skrtic, Vikte Lionikaite, Lina Lawenius, Cecilia Engdahl, Claes Ohlsson, Marie K Lagerquist
American journal of physiology. Endocrinology and metabolism - 2021 -
Vitamin D3 receptor polymorphisms regulate T cells and T cell-dependent inflammatory
diseases
G. F. Lahore, B. Raposo, Marie Lagerquist, Claes Ohlsson, P. Sabatier, B. Z. Xu, M. Aoun, J. James, X. J. Cai, R. A. Zubarev, K. S. Nandakumar, R. Holmdahl
Proceedings of the National Academy of Sciences of the United States of America - 2020 -
Estrogen receptor alpha signaling in extrahypothalamic neurons during late puberty decreases bone size and strength in female but not in male
mice
N. R. Kim, F. Jardi, R. Khalil, L. Antonio, D. Schollaert, L. Deboel, G. H. van Lenthe, B. Decallonne, G. Carmeliet, J. A. Gustafsson, F. Claessens, Claes Ohlsson, Marie Lagerquist, V. Dubois, D. Vanderschueren
Faseb Journal - 2020 -
The effects of estradiol are modulated in a tissue-specific manner in mice with inducible inactivation of ERα after sexual
maturation.
Claes Ohlsson, Helen H. Farman, Karin L. Gustafsson, Jianyao Wu, Petra Henning, Sara H Windahl, Klara Sjögren, Jan-Åke Gustafsson, Sofia Movérare-Skrtic, Marie Lagerquist
American journal of physiology. Endocrinology and metabolism - 2020 -
Interleukin 17A: a Janus-faced regulator of
osteoporosis
Julia M. Scheffler, Louise Grahnemo, Cecilia Engdahl, Christina Drevinge, Karin L. Gustafsson, Carmen Corciulo, Lina Lawenius, Y. Iwakura, Klara Sjögren, Marie Lagerquist, Hans Carlsten, Claes Ohlsson, Ulrika Islander
Scientific Reports - 2020 -
Phosphorylation site S122 in estrogen receptor α has a tissue-dependent role in female
mice
Claes Ohlsson, Karin L. Gustafsson, Helen H. Farman, Petra Henning, Vikte Lionikaite, Sofia Movérare-Skrtic, Klara Sjögren, Anna E Törnqvist, Annica Andersson, Ulrika Islander, Angelina I Bernardi, Matti Poutanen, Pierre Chambon, Marie K Lagerquist
FASEB Journal - 2020 -
Effects of the selective GPER1 agonist G1 on bone
growth
M. Iravani, Marie Lagerquist, E. Karimian, A. S. Chagin, Claes Ohlsson, L. Savendahl
Endocrine Connections - 2019 -
Roles of activating functions 1 and 2 of estrogen receptor α in
lymphopoiesis.
Annica Andersson, Sofia Movérare-Skrtic, Angelina I Bernardi, Helen H. Farman, Pierre Chambon, Cecilia Engdahl, Marie Lagerquist, Sara H Windahl, Hans Carlsten, Claes Ohlsson, Ulrika Islander
The Journal of endocrinology - 2018 -
Increased bone mass in a mouse model with low fat
mass.
Louise Grahnemo, Karin L. Gustafsson, Klara Sjögren, Petra Henning, Vikte Lionikaite, Antti Koskela, Juha Tuukkanen, Claes Ohlsson, Ingrid Wernstedt Asterholm, Marie Lagerquist
American journal of physiology. Endocrinology and metabolism - 2018 -
Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult
mice.
Claes Ohlsson, Petra Henning, Karin H. Nilsson, Jianyao Wu, Karin L. Gustafsson, Klara Sjögren, Anna E Törnqvist, Antti Koskela, Fu-Ping Zhang, Marie Lagerquist, Matti Poutanen, Juha Tuukkanen, Ulf H Lerner, Sofia Movérare-Skrtic
The Journal of endocrinology - 2018 -
Membrane estrogen receptor alpha is essential for estrogen signaling in the male
skeleton
Helen H. Farman, Karin L. Gustafsson, Petra Henning, Louise Grahnemo, Vikte Lionikaite, Sofia Moverare-Skrtic, Jianyao Wu, Henrik Ryberg, A. Koskela, J. Tuukkanen, E. R. Levin, Claes Ohlsson, Marie Lagerquist
Journal of Endocrinology - 2018 -
ER alpha expression in T lymphocytes is dispensable for estrogenic effects in
bone
Karin L. Gustafsson, Karin H. Nilsson, Helen H. Farman, Vikte Lionikaite, Petra Henning, Jianyao Wu, Sara H Windahl, Ulrika Islander, Sofia Moverare-Skrtic, Klara Sjögren, Hans Carlsten, Claes Ohlsson, Marie Lagerquist
Journal of Endocrinology - 2018 -
Extra-nuclear effects of estrogen on cortical bone in males require
ERαAF-1
Helen H. Farman, Jianyao Wu, Karin L. Gustafsson, Sara H Windahl, S. H. Kim, J. A. Katzenellenbogen, Claes Ohlsson, Marie Lagerquist
Journal of Molecular Endocrinology - 2017 -
Regulation of bone growth via ligand-specific activation of estrogen receptor
alpha.
Maryam Iravani, Marie Lagerquist, Claes Ohlsson, Lars Savendahl
The Journal of endocrinology - 2017 -
Female Mice Lacking Estrogen Receptor-alpha in Hypothalamic Proopiomelanocortin (POMC) Neurons Display Enhanced Estrogenic Response on Cortical Bone
Mass
Helen H. Farman, Sara H Windahl, Lars Westberg, H. Isaksson, Emil Egecioglu, Erik Schéle, Henrik Ryberg, John-Olov Jansson, J. Tuukkanen, A. Koskela, S. K. Xie, L. Hahner, J. Zehr, D. J. Clegg, Marie K Lagerquist, Claes Ohlsson
Endocrinology - 2016 -
SERMs have substance-specific effects on bone, and these effects are mediated via ER alpha AF-1 in female
mice
Anna E Börjesson, Helen H. Farman, Sofia Movérare-Skrtic, Cecilia Engdahl, M. C. Antal, A. Koskela, J. Tuukkanen, Hans Carlsten, A. Krust, P. Chambon, Klara Sjögren, Marie K Lagerquist, Sara H Windahl, Claes Ohlsson
American Journal of Physiology-Endocrinology and Metabolism - 2016 -
The role of membrane ER alpha signaling in bone and other major estrogen responsive
tissues
Karin L. Gustafsson, Helen H. Farman, Petra Henning, Vikte Lionikaite, Sofia Movérare-Skrtic, Jianyao Wu, Henrik Ryberg, A. Koskela, J. A. Gustafsson, J. Tuukkanen, E. R. Levin, Claes Ohlsson, Marie K Lagerquist
Scientific Reports - 2016 -
Measurement of a comprehensive sex steroid profile in rodent serum by high-sensitive gas chromatography-tandem mass
spectrometry.
Maria E. Nilsson, Liesbeth Vandenput, Åsa Tivesten, Anna-Karin Norlén, Marie K Lagerquist, Sara H Windahl, Anna E Börjesson, Helen H. Farman, Matti Poutanen, Anna Benrick, Manuel Maliqueo, Elisabet Stener-Victorin, Henrik Ryberg, Claes Ohlsson
Endocrinology - 2015 -
The effect of estrogen on bone requires ER alpha in nonhematopoietic cells but is enhanced by ER alpha in hematopoietic
cells
Petra Henning, Claes Ohlsson, Cecilia Engdahl, Helen H. Farman, Sara H Windahl, Hans Carlsten, Marie K Lagerquist
American Journal of Physiology-Endocrinology and Metabolism - 2014 -
The estrogen receptor antagonist ICI 182,780 can act both as an agonist and an inverse agonist when estrogen receptor α AF-2 is
modified.
Sofia Movérare-Skrtic, Anna E Börjesson, Helen H. Farman, Klara Sjögren, Sara H Windahl, Marie K Lagerquist, Annica Andersson, Alexandra Stubelius, Hans Carlsten, Jan-Åke Gustafsson, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2014 -
The role of activation functions 1 and 2 of estrogen receptor-alpha for the effects of estradiol and selective estrogen receptor modulators in male
mice
Anna E Börjesson, Helen H. Farman, Cecilia Engdahl, A. Koskela, Klara Sjögren, Jenny Kindblom, Alexandra Stubelius, Ulrika Islander, Hans Carlsten, M. C. Antal, A. Krust, P. Chambon, J. Tuukkanen, Marie K Lagerquist, Sara H Windahl, Claes Ohlsson
Journal of Bone and Mineral Research - 2013 -
Periarticular bone loss in antigen-induced
arthritis.
Cecilia Engdahl, Catharina Lindholm, Alexandra Stubelius, Claes Ohlsson, Hans Carlsten, Marie Lagerquist
Arthritis and rheumatism - 2013 -
The role of estrogen receptor α in the regulation of bone and growth plate
cartilage.
Anna E Börjesson, Marie Lagerquist, Sara H Windahl, Claes Ohlsson
Cellular and molecular life sciences : CMLS - 2013 -
Estrogen receptor-alpha in osteocytes is important for trabecular bone formation in male
mice
Sara H Windahl, Anna E Börjesson, Helen H. Farman, Cecilia Engdahl, Sofia Movérare-Skrtic, Klara Sjögren, Marie Lagerquist, Jenny Kindblom, A. Koskela, J. Tuukkanen, P. D. Pajevic, J. Q. Feng, K. Dahlman-Wright, P. Antonson, J. A. Gustafsson, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2013 -
Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not
2.
Sara H Windahl, L Saxon, Anna E Börjesson, Marie Lagerquist, B Frenkel, Petra Henning, Ulf H Lerner, Gl Galea, Lb Meakin, Cecilia Engdahl, Klara Sjögren, Mc Antal, A Krust, P Chambon, LE Lanyon, Js Price, Claes Ohlsson
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 2013 -
Estradiol ameliorates arthritis and protects against systemic bone loss in Staphylococcus aureus infection in
mice
Inger Gjertsson, Erik Kristiansson, Marie Lagerquist, Catharina Lindholm, Hans Carlsten
Arthritis Research & Therapy - 2012 -
Exosomal secretion of death bullets: a new way of apoptotic
escape?
N. Trokovic, R. Pollanen, P. Porola, V. Stegaev, U. Hetzel, Åsa Tivesten, Cecilia Engdahl, Hans Carlsten, Helena Forsblad d'Elia, Johan Bourghardt Fagman, Marie Lagerquist, Y. T. Konttinen
American Journal of Physiology-Endocrinology and Metabolism - 2012 -
The role of estrogen receptor-alpha and its activation function-1 for growth plate closure in female
mice
Anna E Börjesson, Sara H Windahl, E. Karimian, E. E. Eriksson, Marie Lagerquist, Cecilia Engdahl, M. C. Antal, A. Krust, P. Chambon, L. Savendahl, Claes Ohlsson
American Journal of Physiology-Endocrinology and Metabolism - 2012 -
The gut microbiota regulates bone mass in
mice
Klara Sjögren, Cecilia Engdahl, Petra Henning, Ulf H Lerner, Valentina Tremaroli, Marie Lagerquist, Fredrik Bäckhed, Claes Ohlsson
Journal of Bone and Mineral Research - 2012 -
Estrogen receptor-α expression in neuronal cells affects bone
mass.
Claes Ohlsson, Cecilia Engdahl, Anna E Börjesson, Sara H Windahl, Erik Studer, Lars Westberg, Elias Eriksson, Antti Koskela, Juha Tuukkanen, Andree Krust, Pierre Chambon, Hans Carlsten, Marie Lagerquist
Proceedings of the National Academy of Sciences of the United States of America - 2012 -
Effects of oestradiol and raloxifene on the induction and effector phases of experimental postmenopausal arthritis and secondary
osteoporosis
Caroline Jochems, Ulrika Islander, Malin Erlandsson, Cecilia Engdahl, Marie Lagerquist, Claes Ohlsson, Kutty Selva Nandakumar, Rikard Holmdahl, Hans Carlsten
Clinical and Experimental Immunology - 2011 -
Roles of transactivating functions 1 and 2 of estrogen receptor-alpha in
bone.
Anna E Börjesson, Sara H Windahl, Marie Lagerquist, Cecilia Engdahl, B Frenkel, Sofia Movérare-Skrtic, Klara Sjögren, Jenny Kindblom, Alexandra Stubelius, Ulrika Islander, Mc Antal, A Krust, P Chambon, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2011 -
Estrogens in rheumatoid arthritis; the immune system and
bone
Ulrika Islander, Caroline Jochems, Marie Lagerquist, Helena Forsblad d'Elia, Hans Carlsten
Molecular and Cellular Endocrinology - 2011 -
Combined treatment with Dexamethasone and Raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal
arthritis
Ulrika Islander, Caroline Jochems, Alexandra Stubelius, Annica Andersson, Marie Lagerquist, Claes Ohlsson, Hans Carlsten
Arthritis Research and Therapy - 2011 -
Reduced bone mass and muscle strength in male 5α-reductase type 1 inactivated
mice.
Sara H Windahl, Niklas Andersson, Anna E Börjesson, Charlotte Swanson, Johan Svensson, Sofia Movérare-Skrtic, Klara Sjögren, Linus Ruijin Shao, Marie Lagerquist, Claes Ohlsson
PloS one - 2011 -
Role of endogenous and exogenous female sex hormones in arthritis and osteoporosis development in B10.Q-ncf1*/* mice with collagen-induced chronic
arthritis.
Caroline Jochems, Ulrika Islander, Malin Erlandsson, Cecilia Engdahl, Marie Lagerquist, Inger Gjertsson, Claes Ohlsson, Rikard Holmdahl, Hans Carlsten
BMC musculoskeletal disorders - 2010 -
The role of estrogen receptor-alpha in growth plate cartilage for longitudinal bone
growth.
Anna E Börjesson, Marie Lagerquist, C Liu, Linus Ruijin Shao, Sara H Windahl, Camilla Karlsson, Klara Sjögren, Sofia Movérare-Skrtic, Mc Antal, A Krust, Subburaman Mohan, P Chambon, Lars Sävendahl, Claes Ohlsson
Journal of bone and mineral research - 2010 -
Amelioration of collagen-induced arthritis and immune-associated bone loss through signaling via estrogen receptor alpha, and not estrogen receptor beta or G protein-coupled receptor
30.
Cecilia Engdahl, Caroline Jochems, Sara H Windahl, Anna E Börjesson, Claes Ohlsson, Hans Carlsten, Marie Lagerquist
Arthritis and rheumatism - 2010 -
In Vivo activation of gene transcription via estrogen response elements by raloxifene
analogue.
Cecilia Engdahl, Caroline Jochems, Gustafsson, van der Saag, Hans Carlsten, Marie Lagerquist
The Journal of endocrinology - 2009 -
Elevated Aromatase Expression in Osteoblasts Leads to Increased Bone Mass without Systemic Adverse
Effects.
Klara Sjögren, Marie Lagerquist, Sofia Movérare-Skrtic, Niklas Andersson, Sara H Windahl, Charlotte Swanson, Subburaman Mohan, M Poutanen, Claes Ohlsson
Journal of bone and mineral research - 2009 -
The role of the G protein-coupled receptor GPR30 in the effects of estrogen in ovariectomized
mice.
Sara H Windahl, Niklas Andersson, A S Chagin, U E A Mårtensson, Hans Carlsten, B Olde, Charlotte Swanson, Sofia Movérare-Skrtic, L Sävendahl, Marie Lagerquist, L M F Leeb-Lundberg, Claes Ohlsson
American journal of physiology. Endocrinology and metabolism - 2009 -
Liver-derived IGF1 enhances the androgenic response in
prostate.
Johan Svensson, Jon Kindblom, Linus Ruijin Shao, Sofia Movérare-Skrtic, Marie Lagerquist, Niklas Andersson, Klara Sjögren, Katrien Venken, Dirk Vanderschueren, John-Olov Jansson, Olle Isaksson, Claes Ohlsson
The Journal of endocrinology - 2008 -
Long-term anti-arthritic and anti-osteoporotic effects of raloxifene in established experimental postmenopausal
polyarthritis.
Caroline Jochems, Marie Lagerquist, Cecilia Håkansson, Claes Ohlsson, Hans Carlsten
Clinical and experimental immunology - 2008 -
17Beta-estradiol expands IgA-producing B cells in mice deficient for the mu
chain.
Marie Lagerquist, Malin Erlandsson, L Svensson, Ulrika Islander, R Holmdahl, Hans Carlsten
Scandinavian journal of immunology - 2008 -
Identification of Target Cells for the Genomic Effects of Estrogens in
Bone
Sara H Windahl, Marie Lagerquist, Niklas Andersson, Caroline Jochems, Anna Kallkopf, Cecilia Håkansson, J. Inzunza, J. A. Gustafsson, P. T. van der Saag, Hans Carlsten, K. Pettersson, Claes Ohlsson
Endocrinology - 2007 -
Role of raloxifene as a potent inhibitor of experimental postmenopausal polyarthritis and
osteoporosis
Caroline Jochems, Ulrika Islander, Anna Kallkopf, Marie Lagerquist, Claes Ohlsson, Hans Carlsten
Arthritis Rheum - 2007 -
Androgens and the
skeleton.
Marie Lagerquist, Liesbeth Vandenput, Sofia Movérare-Skrtic, Dirk Vanderschueren, Steven Boonen, Roger Bouillon, Claes Ohlsson
Minerva endocrinologica - 2005