Two solid-state NMR spectrometers at SNC
Bruker 400 MHz Ascend DNP NMR spectrometer
- AVANCE Neo Bruker Console
- 263 GHz Gyrotron
- LT-MAS cryocabinet with automatic refill system
- sweep field unit
- 2 NMR probes : 3.2 mm RTMAS HXY, 3.2 mm DNP LTMAS HXY
Varian 600 MHz INOVA NMR spectrometer
- INOVA console
- 3.2 mm RTMAS HXY probe
Solid-state NMR spectroscopy is a powerful technique for the characterization of the atomic-level structure and dynamics of materials. Magic Angle Spinning (MAS) NMR is often the uniquely applicable method for measurement of porosity, and is one of the most effective techniques for molecular-level investigation of interfaces. Both solid-state NMR spectrometers of the 600 MHz and 400 MHz magnets at the Swedish NMR Centre are used for inorganic and organic aggregates in crystalline and amorphous states, composite materials, pharmaceutical formulations, heterogeneous systems including liquid or gas components, suspensions, and molecular aggregates with dimensions on the nano- to microscale.
Sometimes the use of this technique is limited by its lack of sensitivity, which can prevent the observation of surfaces, defects or insensitive isotopes. This is why the 400 MHz magnet at the Swedish NMR Centre is equipped with a gyrotron and able to perform Dynamic Nuclear Polarization (DNP). DNP has been shown to improve by one to three orders of magnitude the sensitivity of NMR experiments on materials under MAS, at high magnetic field. The field of DNP-NMR spectroscopy of materials has undergone a rapid development in the last ten years. Currently, MAS DNP can be applied to a wide range of materials, including organic, hybrid and inorganic materials with applications to fields such as catalysis, polymers, pharma, optoelectronics. The 400 MHz DNP NMR spectrometer at the Swedish NMR Centre can provide sensitivity enhancement that grant insights for the characterization of pharmaceutical formulations and the surface of inorganic particles and mesoporous materials.