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- Sofia Töyrä Silfverswärd
Sofia Töyrä Silfverswärd
Research Coordinator
Department of Clinical Neuroscience-
Real-world outcomes of Aflibercept 8 mg in previously treated neovascular AMD
patients.
Imadeddin Abu Ishkheidem, Esra Inci, Martin Breimer, Sofia Töyrä Silfverswärd, Madeleine Zetterberg, Marita Andersson Grönlund
FLOretina, Florence, Italy, 4-7 December, 2025 - 2025 -
Real-world outcomes of Aflibercept 8 mg in previously treated neovascular AMD
patients
Imadeddin Abu Ishkheidem, Esra Inci, Martin Breimer, Sofia Töyrä Silfverswärd, Madeleine Zetterberg, Marita Andersson Grönlund
EUretina, Paris, France, 4-7 September, 2025 - 2025 -
Real-world outcomes of aflibercept 8 mg in patients previously treated for neovascular age-related macular
degeneration
Imadeddin Abu Ishkheidem, Esra Inci, Martin Breimer, Sofia Töyrä Silfverswärd, Madeleine Zetterberg, Marita Andersson Grönlund
Acta Ophthalmologica - 2025 -
Insulin Sensitivity Controls Activity of Pathogenic CD4+T Cells in Rheumatoid
Arthritis
Malin Erlandsson, Eric Malmhäll-Bah, Venkataragavan Chandrasekaran, Karin Andersson, Lisa M Nilsson, Sofia Töyrä Silfverswärd, Rille Pullerits, Maria Bokarewa
CELLS - 2024 -
MicroRNA and interleukin 6 interplay in the adipose tissue of rheumatoid arthritis
patients.
Carolina Larsson, Karin Andersson, Mitra Nadali, Sofia Töyrä Silfverswärd, Maria Bokarewa, Malin Erlandsson
Clinical and experimental rheumatology - 2023 -
Metabolic signature and proteasome activity controls synovial migration of CDC42hiCD14+ cells in rheumatoid
arthritis.
Eric Malmhäll-Bah, Karin Andersson, Malin Erlandsson, Sofia Silfverswärd Lindblad, Rille Pullerits, Maria Bokarewa
Frontiers in immunology - 2023 -
IGF1R signalling is a guardian of self-tolerance restricting autoantibody
production.
Malin Erlandsson, Seval Erdogan, Caroline Wasén, Karin Andersson, Sofia Töyrä Silfverswärd, Rille Pullerits, Mats Bemark, Maria Bokarewa
Frontiers in immunology - 2022 -
Survivin promotes a glycolytic switch in CD4+ T cells by suppressing the transcription of PFKFB3 in rheumatoid
arthritis.
Malin Erlandsson, Karin Andersson, Nina Oparina, Venkataragavan Chandrasekaran, Tibor Saghy, Anastasios Damdimopoulos, Maria-Jose Garcia-Bonete, Zakaria Einbeigi, Sofia Töyrä Silfverswärd, Marcela Pekna, Gergely Katona, Maria Bokarewa
iScience - 2022 -
Cohesin-Mediated Chromatin Interactions and
Autoimmunity
Venkataragavan Chandrasekaran, N. Oparina, Maria-Jose Garcia-Bonete, C. Wasen, Malin Erlandsson, Eric Malmhäll-Bah, Karin Andersson, Maja Jensen, Sofia Töyrä Silfverswärd, Gergely Katona, Maria Bokarewa
Frontiers in Immunology - 2022 -
Clinical Significance of Diabetes-Mellitus-Associated Antibodies in Rheumatoid
Arthritis
Malin Erlandsson, Mahomud Tuameh, Elin Jukic Huduti, Sofia Töyrä Silfverswärd, Rille Pullerits, Maria Bokarewa
Cells - 2022 -
Impact of the Uncoupling Protein 1 on Cardiovascular Risk in Patients with Rheumatoid
Arthritis
Lovisa Lyngfelt, Malin Erlandsson, Mitra Nadali, Shahram Hedjazifar, Rille Pullerits, Karin Andersson, Petra Brembeck, Sofia Töyrä Silfverswärd, Ulf Smith, Maria Bokarewa
Cells - 2021 -
Low Soluble Receptor for Advanced Glycation End Products Precedes and Predicts Cardiometabolic Events in Women With Rheumatoid
Arthritis
Mitra Nadali, Lovisa Lyngfelt, Malin Erlandsson, Sofia Töyrä Silfverswärd, Karin Andersson, Maria Bokarewa, Rille Pullerits
Frontiers in Medicine - 2021 -
Nicotine Changes the microRNA Profile to Regulate the FOXO Memory Program of CD8(+)T Cells in Rheumatoid
Arthritis
Caroline Wasén, C. Ospelt, Alessandro Camponeschi, Malin Erlandsson, Karin Andersson, Sofia Töyrä Silfverswärd, S. Gay, Maria Bokarewa
Frontiers in Immunology - 2020 -
Low serum IGF1 is associated with hypertension and predicts early cardiovascular events in women with rheumatoid
arthritis
Malin Erlandsson, Lovisa Lyngfelt, N David Åberg, Caroline Wasén, Rachelle A. Espino, Sofia Töyrä Silfverswärd, Mitra Nadali, Katarina Jood, Karin Andersson, Rille Pullerits, Maria Bokarewa
BMC Med - 2019 -
Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid
arthritis.
Karin Andersson, Caroline Wasén, Lina Juzokaite, Lovisa Leifsdottir, Malin Erlandsson, Sofia Töyrä Silfverswärd, Anna Stokowska, Marcela Pekna, Milos Pekny, Kjell Olmarker, Rolf A. Heckemann, Marie Kalm, Maria Bokarewa
Proceedings of the National Academy of Sciences of the United States of America - 2018 -
Smoking Is Associated With Low Levels of Soluble PD-L1 in Rheumatoid
Arthritis
Caroline Wasén, Malin Erlandsson, Apostolos Bossios, Linda Ekerljung, Carina Malmhäll, Sofia Töyrä Silfverswärd, Rille Pullerits, Bo Lundbäck, Maria Bokarewa
Frontiers in Immunology - 2018 -
High Expression of STAT3 in Subcutaneous Adipose Tissue Associates with Cardiovascular Risk in Women with Rheumatoid
Arthritis.
Mitra Nadali, Rille Pullerits, Karin Andersson, Sofia Silfverswärd Lindblad, Malin Erlandsson, Maria Bokarewa
International journal of molecular sciences - 2017 -
IGF-1R signalling contributes to IL-6 production and T cell dependent inflammation in rheumatoid
arthritis.
Malin Erlandsson, Sofia Silfverswärd Lindblad, Mitra Nadali, Minna Turkkila, Mattias Svensson, Ing-Marie Jonsson, Karin Andersson, Maria Bokarewa
Biochimica et Biophysica Acta - Molecular basis of disease - 2017 -
Survivin in autoimmune
diseases.
Giacomo Gravina, Caroline Wasén, Maria-Jose Garcia-Bonete, Minna Turkkila, Malin Erlandsson, Sofia Silfverswärd Lindblad, Mikael Brisslert, Rille Pullerits, Karin Andersson, Gergely Katona, Maria Bokarewa
Autoimmunity reviews - 2017 -
Smoking activates cytotoxic CD8(+) T cells and causes survivin release in rheumatoid
arthritis
Caroline Wasén, Minna Turkkila, Apostolos Bossios, Malin Erlandsson, Karin Andersson, Linda Ekerljung, Carina Malmhäll, Mikael Brisslert, Sofia Silfverswärd Lindblad, Bo Lundbäck, Maria Bokarewa
Journal of Autoimmunity - 2017 -
Survivin controls biogenesis of microRNA in smokers: A link to pathogenesis of rheumatoid
arthritis.
Karin Andersson, Minna Turkkila, Malin Erlandsson, Apostolos Bossios, Sofia Silfverswärd Lindblad, Dan Hu, Linda Ekerljung, Carina Malmhäll, Howard L. Weiner, Bo Lundbäck, Maria Bokarewa
Biochimica et biophysica acta - 2017 -
Smoking Functions as a Negative Regulator of IGF1 and Impairs Adipokine Network in Patients with Rheumatoid
Arthritis.
Malin Erlandsson, Roberto Doria Medina, Sofia Silfverswärd Lindblad, Maria Bokarewa
Mediators of inflammation - 2016 -
Pathogenic Transdifferentiation of Th17 Cells Contribute to Perpetuation of Rheumatoid Arthritis during Anti-TNF
Treatment.
Karin Andersson, Nicola Cavallini, Dan Hu, Mikael Brisslert, Ron Cialic, Hadi Valadi, Malin Erlandsson, Sofia Silfverswärd Lindblad, Rille Pullerits, Vijay K Kuchroo, Howard L Weiner, Maria Bokarewa
Molecular medicine (Cambridge, Mass.) - 2015 -
Suppressed diversity of survivin splicing in active rheumatoid
arthritis
Minna Turkkila, Karin Andersson, S. Amu, Mikael Brisslert, Malin Erlandsson, Sofia Silfverswärd Lindblad, Maria Bokarewa
Arthritis Research & Therapy - 2015 -
The N-Methyl-D-Aspartic Acid Receptor Antagonist Memantine Ameliorates and Delays the Development of Arthritis by Enhancing Regulatory T
Cells.
Sofia S Lindblad, Piotr Mydel, Annelie Hellvard, Ing-Marie Jonsson, Maria Bokarewa
Neuro-Signals - 2012 -
Role of environmental toxins in chronic experimental arthrithis - in search for anti-inflammatory pathways of ethanol and
nicotine
-
Smoking and nicotine exposure delay development of collagen-induced arthritis in
mice.
Sofia Silfverswärd Lindblad, Piotr Mydel, Ing-Marie Jonsson, Robert M Senior, Andrej Tarkowski, Maria Bokarewa
Arthritis research & therapy - 2009 -
Ethanol prevents development of destructive
arthritis
Ing-Marie Jonsson, Margareta Verdrengh, Mikael Brisslert, Sofia Silfverswärd Lindblad, Maria Bokarewa, Ulrika Islander, Hans Carlsten, Claes Ohlsson, K. S. Nandakumar, R. Holmdahl, Andrej Tarkowski
Proc Natl Acad Sci U S A - 2007 -
Balance between survivin, a key member of the apoptosis inhibitor family, and its specific antibodies determines erosivity in rheumatoid
arthritis
Maria Bokarewa, Sofia Silfverswärd Lindblad, Demitri Bokarew, Andrej Tarkowski
Arthritis Res Ther - 2005