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- Alexis Moscoso Rial
Alexis Moscoso Rial
Affiliated Researcher
Department of Psychiatry and Neurochemistry-
The effect of Lewy body (co-)pathology on the clinical and imaging phenotype of amnestic
patients
Jesus Silva-Rodriguez, Miguel Ángel Labrador-Espinosa, Linda Zhang, Sandra Castro-Labrador, Francisco Javier Lopez-Gonzalez, Alexis Moscoso Rial, Pascual Sanchez-Juan, Michael Schöll, Michel J. Grothe
BRAIN - 2025 -
Considerations in the clinical use of amyloid PET and CSF biomarkers for Alzheimer's
disease
Antoine Leuzy, Ariane Bollack, Daniela Pellegrino, Charlotte E. Teunissen, Renaud La Joie, Gil D. Rabinovici, Nicolai Franzmeier, Keith Johnson, Frederik Barkhof, Leslie M. Shaw, Alexander Arkhipenko, Suzanne E. Schindler, Lawrence S. Honig, Alexis Moscoso Rial, Michael Schöll, Henrik Zetterberg, Kaj Blennow, Oskar Hansson, Gill Farrar
ALZHEIMERS & DEMENTIA - 2025 -
Hypometabolism and atrophy patterns associated with Niemann-Pick type
C
Jesus Silva-Rodriguez, Cristina Castro, Julia Cortes, Manuel Arias, Virginia Pubul, Alexis Moscoso Rial, Michel J. Grothe, Gabriel Reynes-Llompart, Laura Rodriguez-Bel, Jordi Gascon-Bayarri, Maria Jesus Sobrido, Pablo Aguiar
EJNMMI RESEARCH - 2025 -
Validation Of the Tau Heterogeneity Evaluation in Alzheimer’s Disease (THETA) Score Using Longitudinal and Histopathology
Data
Robel K. Gebre, Alexis Moscoso Rial, Sheelakumari Raghavan, Heather J. Wiste, Fiona Heeman, Alejandro Costoya-Sánchez, Christopher G. Schwarz, Anthony J. Spychalla, Val J. Lowe, Jonathan Graff-Radford, David S. Knopman, Ronald C. Petersen, Michael Schöll, Melissa E. Murray, Clifford R. Jack, Prashanthi Vemuri
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2024 -
Advancing Tau PET Quantification in Alzheimer Disease with Machine Learning: Introducing THETA, a Novel Tau Summary
Measure
Robel K. Gebre, Alexis Moscoso Rial, Sheelakumari Raghavan, Heather J. Wiste, Fiona Heeman, Alejandro Costoya-Sánchez, Christopher G. Schwarz, Anthony J. Spychalla, Val J. Lowe, Jonathan Graff-Radford, David S. Knopman, Ronald C. Petersen, Michael Schöll, Melissa E. Murray, Clifford R. Jack, Prashanthi Vemuri
Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 2024 -
Quantitative brain [18F]FDG PET beyond normal blood glucose
levels
David Rey-Bretal, Lara Garcia-Varela, Noemi Gomez-Lado, Alexis Moscoso Rial, Manuel Pineiro-Fiel, Lucia Diaz-Platas, Santiago Medin, Anxo Fernandez-Ferreiro, Alvaro Ruibal, Tomas Sobrino, Jesus Silva-Rodriguez, Pablo Aguiar
NEUROIMAGE - 2024 -
REAL AD-Validation of a realistic screening approach for early Alzheimer's
disease
Antoine Leuzy, Fiona Heeman, Iris Bosch, Frida Lenér, Maria Dottori, Kajsa Quitz, Alexis Moscoso Rial, Silke Kern, Henrik Zetterberg, Kaj Blennow, Michael Schöll
ALZHEIMERS & DEMENTIA - 2024 -
Scenarios for the long-term efficacy of amyloid-targeting therapies in the context of the natural history of Alzheimer's
disease
Lars Lau Raket, Jeffrey Cummings, Alexis Moscoso Rial, Nicolas Villain, Michael Schöll
ALZHEIMERS & DEMENTIA - 2024 -
Partial volume correction in longitudinal tau PET studies: is it really
needed?
Alejandro Costoya-Sanchez, Alexis Moscoso Rial, Tomas Sobrino, Alvaro Ruibal, Michel J. Grothe, Michael Schöll, Jesus Silva-Rodriguez, Pablo Aguiar
NEUROIMAGE - 2024 -
CT-based volumetric measures obtained through deep learning: Association with biomarkers of
neurodegeneration
Meera Srikrishna, Nicholas J. Ashton, Alexis Moscoso Rial, J. B. Pereira, Rolf A. Heckemann, D. van Westen, Giovanni Volpe, Joel Simrén, Anna Zettergren, Silke Kern, L. O. Wahlund, B. Gyanwali, S. Hilal, J. C. Ruifen, Henrik Zetterberg, Kaj Blennow, E. Westman, C. S. P. Chen, Ingmar Skoog, Michael Schöll
Alzheimers & Dementia - 2024 -
Elevated CSF GAP-43 is associated with accelerated tau accumulation and spread in Alzheimer's
disease.
Nicolai Franzmeier, Amir Dehsarvi, Anna Steward, Davina Biel, Anna Dewenter, Sebastian Niclas Roemer, Fabian Wagner, Mattes Groß, Matthias Brendel, Alexis Moscoso Rial, Prithvi Arunachalam, Kaj Blennow, Henrik Zetterberg, Michael Ewers, Michael Schöll
Nature communications - 2024 -
Characteristics of amnestic patients with hypometabolism patterns suggestive of Lewy body
pathology
Jesus Silva-Rodriguez, Miguel A. Labrador-Espinosa, Alexis Moscoso Rial, Michael Schöll, Pablo Mir, Michel J. Grothe
BRAIN - 2023 -
Increased Medial Temporal Tau Positron Emission Tomography Uptake in the Absence of Amyloid-β
Positivity.
Alejandro Costoya-Sánchez, Alexis Moscoso Rial, Jesús Silva-Rodríguez, Michael J Pontecorvo, Michael D Devous, Pablo Aguiar, Michael Schöll, Michel J. Grothe
JAMA neurology - 2023 -
Combining tau-PET and fMRI meta-analyses for patient-centered prediction of cognitive decline in Alzheimer's
disease
D. Biel, Y. Luan, M. Brendel, P. Hager, A. Dewenter, Alexis Moscoso Rial, D. O. Svaldi, I. A. Higgins, M. Pontecorvo, S. Romer, A. Steward, A. Rubinski, L. K. Zheng, Michael Schöll, S. Shcherbinin, M. Ewers, N. Franzmeier
Alzheimers Research & Therapy - 2022 -
Differential diagnosis of amnestic dementia patients based on an FDG-PET signature of autopsy-confirmed
LATE-NC.
Michel J. Grothe, Alexis Moscoso Rial, Jesús Silva-Rodríguez, Catharina Lange, Kwangsik Nho, Andrew J Saykin, Peter T Nelson, Michael Schöll, Ralph Buchert, Stefan Teipel
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2022 -
CSF biomarkers and plasma p-tau181 as predictors of longitudinal tau accumulation: Implications for clinical trial
design
Alexis Moscoso Rial, Thomas Karikari, Michel J. Grothe, Nicholas J. Ashton, Juan Lantero Rodriguez, Anniina Snellman, Henrik Zetterberg, Kaj Blennow, Michael Schöll
Alzheimer's and Dementia - 2022 -
Impact of spill-in counts from off-target regions on F-18 Flortaucipir PET
quantification
F. J. Lopez-Gonzalez, A. Costoya-Sanchez, J. Paredes-Pacheco, Alexis Moscoso Rial, J. Silva-Rodriguez, P. Aguiar
Neuroimage - 2022 -
F-18-florbetapir PET as a marker of myelin integrity across the Alzheimer's disease
spectrum
Alexis Moscoso Rial, J. Silva-Rodriguez, J. M. Aldrey, J. Cortes, J. M. Pias-Peleteiro, A. Ruibal, Pablo Aguiar, Initia Alzheimers Dis Neuroimaging
European Journal of Nuclear Medicine and Molecular Imaging - 2022 -
Imaging tau pathology in Alzheimer's disease with positron emission tomography: lessons learned from imaging-neuropathology validation
studies
Alexis Moscoso Rial, M. C. Wren, T. Lashley, E. Arstad, M. E. Murray, N. C. Fox, K. Sander, Michael Schöll
Molecular Neurodegeneration - 2022 -
Associations of Fully Automated CSF and Novel Plasma Biomarkers With Alzheimer Disease Neuropathology at
Autopsy.
Michel J. Grothe, Alexis Moscoso Rial, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, Anniina Snellman, Henrik Zetterberg, Kaj Blennow, Michael Schöll
Neurology - 2021 -
Reduced [18F]flortaucipir retention in white matter hyperintensities compared to normal-appearing white
matter.
Michael Schöll, Alexis Moscoso Rial, Michel J. Grothe
European journal of nuclear medicine and molecular imaging - 2021 -
Differential associations of APOE-epsilon 2 and APOE-epsilon 4 alleles with PET-measured amyloid-beta and tau deposition in older individuals without
dementia
G. Salvado, Michel J. Grothe, C. Groot, Alexis Moscoso Rial, Michael Schöll, J. D. Gispert, R. Ossenkoppele
European Journal of Nuclear Medicine and Molecular Imaging - 2021 -
Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer
Disease.
Alexis Moscoso Rial, Michel J. Grothe, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, Anniina Snellman, Marc Suárez-Calvet, Kaj Blennow, Henrik Zetterberg, Michael Schöll
JAMA Neurology - 2021 -
Time course of phosphorylated-tau181 in blood across the Alzheimer's disease
spectrum.
Alexis Moscoso Rial, Michel J. Grothe, Nicholas J. Ashton, Thomas Karikari, Juan Lantero Rodriguez, Anniina Snellman, Marc Suarez-Calvet, Henrik Zetterberg, Kaj Blennow, Michael Schöll
Brain : a journal of neurology - 2021 -
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer's Disease Neuroimaging
Initiative.
Thomas Karikari, Andréa L Benedet, Nicholas J. Ashton, Juan Lantero Rodriguez, Anniina Snellman, Marc Suárez-Calvet, Paramita Saha-Chaudhuri, Firoza Lussier, Hlin Kvartsberg, Alexis Moscoso Rial, Tharick A Pascoal, Ulf Andreasson, Michael Schöll, Michael W Weiner, Pedro Rosa-Neto, John Q Trojanowski, Leslie M Shaw, Kaj Blennow, Henrik Zetterberg
Molecular psychiatry - 2021