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- Martina Sundqvist
Martina Sundqvist
Forskare
Avd för reumatologi och inflammationsforskning-
Targeting CD38 with monoclonal antibodies disrupts key survival pathways in paediatric Burkitt's lymphoma malignant B
cells
Kathrin Klaesener, Nadja Herrmann, Liliana Håversen, Timothy Sundell, Martina Sundqvist, Christina Lundqvist, Paul Manna, Charlotte A Jonsson, Marcella Visentini, Diana Ljung Sass, Sarah McGrath, Kristoffer Grimstad, Alaitz Aranburu, Karin Mellgren, Linda Fogelstrand, Huamei Forsman, Olov Ekwall, Jan Borén, Inger Gjertsson, Michael Reth, Inga-Lill Mårtensson, Alessandro Camponeschi
CLINICAL & TRANSLATIONAL IMMUNOLOGY - 2024 -
Signaling by Neutrophil G Protein-Coupled Receptors that Regulate the Release of Superoxide
Anions.
Claes Dahlgren, Huamei Forsman, Martina Sundqvist, Lena Björkman, Jonas Mårtensson
Journal of Leukocyte Biology - 2024 -
Function and regulation of GPR84 in human
neutrophils
Huamei Forsman, Claes Dahlgren, Jonas Mårtensson, Lena Björkman, Martina Sundqvist
British Journal of Pharmacology - 2024 -
Larixol is not an inhibitor of Gα<inf>i</inf> containing G proteins and lacks effect on signaling mediated by human neutrophil expressed formyl peptide
receptors
Lena Björkman, Huamei Forsman, Linda Bergqvist, Claes Dahlgren, Martina Sundqvist
Biochemical Pharmacology - 2024 -
Lipid Nanoparticles Deliver the Therapeutic VEGFA mRNA In Vitro and In Vivo and Transform Extracellular Vesicles for Their Functional
Extensions
Muhammad Nawaz, Sepideh Heydarkhan-Hagvall, Benyapa Tangruksa, Hernán González-King Garibotti, Yujia Jing, Maugeri Marco, Franziska Kohl, Leif Hultin, Azadeh Reyahi, Alessandro Camponeschi, Bengt Kull, Jonas Christoffersson, Ola Grimsholm, Karin Jennbacken, Martina Sundqvist, John Wiseman, Abdel Wahad Bidar, Lennart Lindfors, Jane Synnergren, Hadi Valadi
Advanced Science - 2023 -
The ketone body acetoacetate activates human neutrophils through
FFAR2.
Jonas Mårtensson, Lena Björkman, Simon Lind, Moa Viklund, Linjie Zhang, Saray Gutierrez, Claes Dahlgren, Martina Sundqvist, Xin Xie, Huamei Forsman
Journal of leukocyte biology - 2023 -
An increase in the cytosolic concentration of free calcium ions activates the neutrophil NADPH-oxidase provided that the free fatty acid receptor 2 has been allosterically
modulated.
Simon Lind, Yanling Wu, Martina Sundqvist, Huamei Forsman, Claes Dahlgren
Cellular signalling - 2023 -
AZ2158 is a more potent formyl peptide receptor 1 inhibitor than the commonly used peptide antagonists in abolishing neutrophil
chemotaxis.
Huamei Forsman, Yanling Wu, Jonas Mårtensson, Lena Björkman, Kenneth L Granberg, Claes Dahlgren, Martina Sundqvist
Biochemical pharmacology - 2023 -
Novel inhibitory effect of galectin-3 on the respiratory burst induced by Staphylococcus aureus in human
neutrophils.
Vignesh Venkatakrishnan, Jonas Elmwall, Trisha Lahiri, Martina Sundqvist, Linda Bergqvist, Hakon Leffler, Ulf J Nilsson, Amanda Welin, Johan Bylund, Anna Karlsson-Bengtsson
Glycobiology - 2023 -
Severe chronic non-bacterial osteomyelitis in combination with total MPO deficiency and responsiveness to TNFα
inhibition
Martina Sundqvist, Karin Christenson, Per Wekell, Halla Björnsdottir, Agnes Dahlstrand Rudin, Felix Peter Sanchez Klose, Tilmann Kallinich, Amanda Welin, Lena Björkman, Johan Bylund, Anna Karlsson, Stefan Berg
Frontiers in Immunology - 2023 -
Structural Determinants in the Staphylococcus aureus-Derived Phenol-Soluble Modulin α2 Peptide Required for Neutrophil Formyl Peptide Receptor
Activation
Moa Viklund, Johanna Fredriksson, André Holdfeldt, Simon Lind, H. Franzyk, Claes Dahlgren, Martina Sundqvist, Huamei Forsman
Journal of Immunology - 2022 -
Pathogenic variant c.1052T>A (p.Leu351Gln) in adenosine deaminase 2 impairs secretion and elevates type I IFN responsive gene
expression.
Sarah M Bowers, Martina Sundqvist, Paul Dancey, David A Cabral, Kelly L Brown
Frontiers in immunology - 2022 -
G protein coupled pattern recognition receptors expressed in neutrophils: Recognition, activation/modulation, signaling and receptor regulated
functions.
Claes Dahlgren, Simon Lind, Jonas Mårtensson, Lena Björkman, Yanling Wu, Martina Sundqvist, Huamei Forsman
Immunological reviews - 2022 -
Human CD38 regulates B cell antigen receptor dynamic organization in normal and malignant B
cells.
Alessandro Camponeschi, Kathrin Kläsener, Timothy Sundell, Christina Lundqvist, Paul T Manna, Negar Ayoubzadeh, Martina Sundqvist, Katrin Thorarinsdottir, Mariele Gatto, Marcella Visentini, Karin Önnheim, Alaitz Aranburu, Huamei Forsman, Olov Ekwall, Linda Fogelstrand, Inger Gjertsson, Michael Reth, Inga-Lill Mårtensson
The Journal of experimental medicine - 2022 -
GRK2 selectively attenuates the neutrophil NADPH-oxidase response triggered by beta-arrestin recruiting GPR84
agonists
Johanna Fredriksson, André Holdfeldt, Jonas Mårtensson, Lena Björkman, T. C. Moller, E. Mullers, Claes Dahlgren, Martina Sundqvist, Huamei Forsman
Biochimica Et Biophysica Acta-Molecular Cell Research - 2022 -
Systemic Galectin-3 in Smokers with Chronic Obstructive Pulmonary Disease and Chronic Bronchitis: The Impact of
Exacerbations
Martina Sundqvist, Kristina Andelid, Ann Ekberg-Jansson, Johan Bylund, Anna Karlsson-Bengtsson, A. Linden
International Journal of Chronic Obstructive Pulmonary Disease - 2021 -
A rare CTSC mutation in Papillon-Lefèvre Syndrome results in abolished serine protease activity and reduced NET formation but otherwise normal neutrophil
function.
Felix Peter Sanchez Klose, Halla Björnsdottir, Agnes Dahlstrand Rudin, Tishana Persson, Arsham Khamzeh, Martina Sundqvist, Sara Thorbert-Mros, Regis Dieckmann, Karin Christenson, Johan Bylund
PloS one - 2021 -
The Two Formyl Peptide Receptors Differently Regulate GPR84-Mediated Neutrophil NADPH Oxidase
Activity
Jonas Mårtensson, Martina Sundqvist, A. Manandhar, L. Leremias, L. J. Zhang, T. Ulven, X. Xie, Lena Björkman, Huamei Forsman
Journal of Innate Immunity - 2021 -
Children with systemic autoinflammatory diseases have multiple, mixed ethnicities that reflect regional ethnic
diversity.
Lori B Tucker, Iwona Niemietz, Preet Mangat, Maria Belen, Jenny Tekano, David A Cabral, Jaime Guzman, Kristin M Houghton, Kimberly A Morishita, Mercedes O Chan, Andrea Human, Martina Sundqvist, Kelly L Brown
Clinical and experimental rheumatology - 2021 -
Neutrophil Signaling That Challenges Dogmata of G Protein-Coupled Receptor Regulated
Functions
Claes Dahlgren, André Holdfeldt, Simon Lind, Jonas Mårtensson, Michael Gabl, Lena Björkman, Martina Sundqvist, Huamei Forsman
ACS Pharmacology and Translational Science - 2020 -
Decrease of core 2 O-glycans on synovial lubricin in osteoarthritis reduces galectin-3 mediated
crosslinking.
Sarah A. Flowers, Kristina A Thomsson, Liaqat Ali, Shan Huang, Yolanda H. Mthembu, Suresh C Regmi, Jan Holgersson, Tannin A Schmidt, Ola Rolfson, Lena Björkman, Martina Sundqvist, Anna Karlsson-Bengtsson, Gregory D Jay, Thomas Eisler, Roman Krawetz, Niclas G. Karlsson
The Journal of biological chemistry - 2020 -
Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor
endocytosis
Martina Sundqvist, André Holdfeldt, S. C. Wright, T. C. Moller, Esther Siaw, K. Jennbacken, H. Franzyk, M. Bouvier, Claes Dahlgren, Huamei Forsman
Biochimica Et Biophysica Acta-Molecular Cell Research - 2020 -
Interdependent allosteric free fatty acid receptor 2 modulators synergistically induce functional selective activation and desensitization in
neutrophils
Simon Lind, André Holdfeldt, Jonas Mårtensson, Martina Sundqvist, T. P. Kenakin, Lena Björkman, Huamei Forsman, Claes Dahlgren
Biochimica Et Biophysica Acta-Molecular Cell Research - 2020 -
Anti-neutrophil cytoplasmic antibodies (ANCA): Antigen interactions and downstream
effects.
Martina Sundqvist, Kristen M Gibson, Sarah M Bowers, Iwona Niemietz, Kelly L Brown
Journal of leukocyte biology - 2020 -
Hyaluronan primes the oxidative burst in human
neutrophils.
Iwona Niemietz, Abigail T Moraes, Martina Sundqvist, Kelly L Brown
Journal of leukocyte biology - 2020 -
Data showing effects of a PI3K-delta inhibitor on neutrophil superoxide production during FPR2 activation and
reactivation
André Holdfeldt, Martina Sundqvist, Claes Dahlgren, Huamei Forsman
Data in Brief - 2020 -
Measurement of Respiratory Burst Products, Released or Retained, During Activation of Professional
Phagocytes.
Claes Dahlgren, Halla Björnsdottir, Martina Sundqvist, Karin Christenson, Johan Bylund
Methods in molecular biology (Clifton, N.J.) Vol 2087. - 2020 -
Linkage between endosomal escape of LNP-mRNA and loading into EVs for transport to other
cells
Maugeri Marco, Muhammad Nawaz, Alexandros Papadimitriou, Annelie Angerfors, Alessandro Camponeschi, Manli Na, Mikko Hölttä, Pia Skantze, Svante Johansson, Martina Sundqvist, Johnny Lindquist, Tomas Kjellman, Inga-Lill Mårtensson, Tao Jin, Per Sunnerhagen, Sofia Östman, Lennart Lindfors, Hadi Valadi
Nature Communications - 2019 -
Functional selective ATP receptor signaling controlled by the free fatty acid receptor 2 through a novel allosteric modulation
mechanism.
Simon Lind, André Holdfeldt, Jonas Mårtensson, Martina Sundqvist, Lena Björkman, Huamei Forsman, Claes Dahlgren
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2019 -
Identification of Residues Critical for FPR2 Activation by the Cryptic Peptide Mitocryptide-2 Originating from the Mitochondrial DNA-Encoded Cytochrome
b.
Simon Lind, Michael Gabl, André Holdfeldt, Jonas Mårtensson, Martina Sundqvist, Kodai Nishino, Claes Dahlgren, Hidehito Mukai, Huamei Forsman
Journal of immunology (Baltimore, Md. : 1950) - 2019 -
Functional characteristics of circulating granulocytes in severe congenital neutropenia caused by ELANE
mutations
Q. Liu, Martina Sundqvist, W. Y. Li, André Holdfeldt, L. Zhang, Lena Björkman, Johan Bylund, Claes Dahlgren, C. Wang, X. D. Zhao, Huamei Forsman
Bmc Pediatrics - 2019 -
Functional and signaling characterization of the neutrophil FPR2 selective agonist
Act-389949
Simon Lind, Martina Sundqvist, R. Holmdahl, Claes Dahlgren, Huamei Forsman, P. Olofsson
Biochemical Pharmacology - 2019 -
Staphylococcus aureus-Derived PSMα Peptides Activate Neutrophil FPR2 but Lack the Ability to Mediate β-Arrestin Recruitment and
Chemotaxis.
Martina Sundqvist, Karin Christenson, André Holdfeldt, Karin Jennbacken, Thor C Møller, Claes Dahlgren, Huamei Forsman
Journal of immunology - 2019 -
Formyl peptide receptor 2 orchestrates mucosal protection against Citrobacter rodentium
infection
Sinan Sharba, Vignesh Venkatakrishnan, Médea Padra, Malene Winther, Michael Gabl, Martina Sundqvist, J. Wang, Huamei Forsman, Sara K. Lindén
Virulence - 2019 -
Neutrophil priming that turns natural FFA2R agonists into potent activators of the superoxide generating
NADPH-oxidase
Jonas Mårtensson, André Holdfeldt, Martina Sundqvist, Michael Gabl, T. P. Kenakin, Lena Björkman, Huamei Forsman, Claes Dahlgren
Journal of leukocyte biology - 2018 -
Mitocryptides from Human Mitochondrial DNA-Encoded Proteins Activate Neutrophil Formyl Peptide Receptors: Receptor Preference and Signaling
Properties.
Michael Gabl, Martina Sundqvist, André Holdfeldt, Simon Lind, Jonas Mårtensson, Karin Christenson, Takayuki Marutani, Claes Dahlgren, Hidehito Mukai, Huamei Forsman
Journal of immunology - 2018 -
Galectin-3 type-C self-association on neutrophil surfaces; The carbohydrate recognition domain regulates cell
function
Martina Sundqvist, Amanda Welin, Jonas Elmwall, Veronica Osla, U. J. Nilsson, H. Leffler, Johan Bylund, Anna Karlsson
Journal of Leukocyte Biology - 2018 -
Similarities and differences between the responses induced in human phagocytes through activation of the medium chain fatty acid receptor GPR84 and the short chain fatty acid receptor
FFA2R.
Martina Sundqvist, Karin Christenson, André Holdfeldt, Michael Gabl, Jonas Mårtensson, Lena Björkman, Regis Dieckmann, Claes Dahlgren, Huamei Forsman
Biochimica et biophysica acta - 2018 -
FPR2 signaling without β-arrestin recruitment alters the functional repertoire of
neutrophils.
Michael Gabl, André Holdfeldt, Martina Sundqvist, Jalal Lomei, Claes Dahlgren, Huamei Forsman
Biochemical pharmacology - 2017 -
Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient
Phagocytes
Martina Sundqvist, Karin Christenson, Halla Björnsdottir, Veronica Osla, Anna Karlsson, Claes Dahlgren, D. P. Speert, Anders Fasth, K. L. Brown, Johan Bylund
Frontiers in Immunology - 2017 -
Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in
question
Malene Winther, André Holdfeldt, Martina Sundqvist, Zahra Rajabkhani, Michael Gabl, Johan Bylund, Claes Dahlgren, Huamei Forsman
Plos One - 2017 -
Neutrophils from patients with SAPHO syndrome show no signs of aberrant NADPH oxidase-dependent production of intracellular reactive oxygen
species.
Per Wekell, Halla Björnsdottir, Lena Björkman, Martina Sundqvist, Karin Christenson, Veronica Osla, Stefan Berg, Anders Fasth, Amanda Welin, Johan Bylund, Anna Karlsson
Rheumatology (Oxford, England) - 2016 -
Neutrophil NET formation is regulated from the inside by myeloperoxidase-processed reactive oxygen
species.
Halla Björnsdottir, Amanda Welin, Erik Michaëlsson, Veronica Osla, Stefan Berg, Karin Christenson, Martina Sundqvist, Claes Dahlgren, Anna Karlsson, Johan Bylund
Free radical biology & medicine - 2015 -
Measurement of respiratory burst products, released or retained, during activation of professional
phagocytes.
Johan Bylund, Halla Björnsdottir, Martina Sundqvist, Anna Karlsson, Claes Dahlgren
Methods in molecular biology (Clifton, N.J.) - 2014 -
Increased intracellular oxygen radical production in neutrophils during febrile episodes of PFAPA
syndrome.
Martina Sundqvist, Per Wekell, Veronica Osla, Johan Bylund, Karin Christenson, Karin Sävman, Dirk Foell, David A Cabral, Anders Fasth, Stefan Berg, Kelly Brown, Anna Karlsson
Arthritis and rheumatism - 2013 -
Neutrophil function in health and disease - role of intracellular radicals and galectin-3 as regulators of
inflammation
Martina Sundqvist
2013 -
Cord blood neutrophils display a galectin-3 responsive phenotype accentuated by vaginal
delivery.
Martina Sundqvist, Veronica Osla, Bo Jacobsson, Anna Rudin, Karin Sävman, Anna Karlsson
BMC pediatrics - 2013 -
In vivo-transmigrated human neutrophils are resistant to antiapoptotic
stimulation.
Karin Christenson, Lena Björkman, Jennie Karlsson, Martina Sundqvist, Charlotta Movitz, David P Speert, Claes Dahlgren, Johan Bylund
Journal of leukocyte biology - 2011 -
Profile of blood cells and inflammatory mediators in periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA)
syndrome.
Kelly Brown, Per Wekell, Veronica Osla, Martina Sundqvist, Karin Sävman, Anders Fasth, Anna Karlsson, Stefan Berg
BMC pediatrics - 2010