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- Sara Lindén
Sara Lindén
Professor
Avd för medicinsk kemi och cellbiologi-
Aeromonas salmonicida AI-1 and AI-2 quorum sensing pathways are differentially regulated by rainbow trout mucins and during in vivo
colonization
Stefany Ojaimi Loibman, Macarena P Quintana-Hayashi, Licínia Santos, Sara K. Lindén
FISH & SHELLFISH IMMUNOLOGY - 2024 -
The relationship between secondary school course choices, language proficiency and academic performance among Swedish pharmacy
students
Mattias Erhardsson, Patrik Aronsson, Sara K. Lindén
Pharmacy Education - 2024 -
Characterization of the rainbow trout (Oncorhynchus mykiss) mucosal glycosphingolipid repertoire and Aeromonas salmonicida binding to neutral
glycosphingolipids
John Benktander, Henrik Sundh, Kristina Sundell, Sinan Sharba, Susann Teneberg, Sara K. Lindén
Glycobiology - 2024 -
Gilthead seabream mucus glycosylation is complex, differs between epithelial sites and carries unusual poly N-acetylhexosamine
motifs
Kristina A Thomsson, John Benktander, Socorro Toxqui-Rodriguez, M. Carla Piazzon, Sara K. Lindén
Fish and Shellfish Immunology - 2024 -
Expression Levels of MUC5AC and MUC5B in Airway Goblet Cells Are Associated with Traits of COPD and Progression of Chronic Airflow
Limitation
Terezia Pincikova, Heta Merikallio, Ioanna Kotortsi, Reza Karimi, Chuan-Xing Li, Elisa Lappi-Blanco, Sara K. Lindén, Médea Padra, asa M. Wheelock, Sven Nyren, Carl Magnus Skold, Riitta L. Kaarteenaho
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2024 -
Differentiation of Pig Gastric Primary Cells into Mucus Producing Epithelial
Cells
Macarena P Quintana-Hayashi, Sinan Sharba, Sara K. Lindén
Methods in Molecular Biology - 2024 -
<i>In vitro</i> fish mucosal surfaces producing mucin as a model for studying host-pathogen
interactions
Macarena P Quintana-Hayashi, Kristina A. Thomsson Hulthe, Sara K. Lindén
PLOS ONE - 2024 -
Protein N-glycosylation in the bronchoalveolar space differs between never-smokers and long-term smokers with and without
COPD.
Vignesh Venkatakrishnan, Kristina A Thomsson, Médea Padra, Anders Andersson, Bettina Brundin, Karin Christenson, Johan Bylund, Niclas G. Karlsson, Anders Lindén, Sara K. Lindén
Glycobiology - 2023 -
Identification of Novel Glycans in the Mucus Layer of Shark and Skate
Skin
Etty Bachar-Wikstrom, Kristina A Thomsson, Carina Sihlbom, Lisa Abbo, Haitham Tartor, Sara K. Lindén, Jakob D. Wikstrom
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2023 -
Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen
infection
George M. H. Birchenough, Björn O. Schröder, Sinan Sharba, Liisa Arike, Christian V Recktenwald, F. Puertolas-Balint, Mahadevan Subramani, Karl Hansson, B. Yilmaz, Sara K. Lindén, Fredrik Bäckhed, Gunnar C. Hansson
Cell Reports - 2023 -
Porcine intestinal glycosphingolipids recognized by Brachyspira
hyodysenteriae
Macarena P Quintana-Hayashi, Dani Zalem, Sara K. Lindén, Susann Teneberg
Microbial Pathogenesis - 2023 -
Mass Spectrometry Analysis of Shark Skin
Proteins
Etty Bachar-Wikstrom, Braham Dhillon, Navi Gill Dhillon, Lisa Abbo, Sara K. Lindén, Jakob D. Wikstrom
International Journal of Molecular Sciences - 2023 -
Glucose Homeostasis in Relation to Neutrophil Mobilization in Smokers with
COPD
N. Pournaras, Anders Andersson, M. A. Kovach, Médea Padra, K. F. Che, B. Brundin, S. Yoshihara, S. Bozinovski, Sara K. Lindén, Per-Anders Jansson, M. C. Skold, Ingemar Qvarfordt, A. Linden
International Journal of Chronic Obstructive Pulmonary Disease - 2022 -
Aeromonas salmonicida binds α2-6 linked sialic acid, which is absent among the glycosphingolipid repertoires from skin, gill, stomach, pyloric caecum, and
intestine
John Benktander, Henrik Sundh, Sinan Sharba, Susann Teneberg, Sara K. Lindén
Virulence - 2022 -
Atlantic Salmon Mucins Inhibit LuxS-Dependent A. Salmonicida AI-2 Quorum Sensing in an N-Acetylneuraminic Acid-Dependent
Manner
János T Padra, Stefany Ojaimi Loibman, Kaisa Thorell, Henrik Sundh, Kristina Sundell, Sara K. Lindén
International Journal of Molecular Sciences - 2022 -
Optimization of Alcian blue pH 1.0 histo-staining protocols to match mass spectrometric quantification of sulfomucins and circumvent false positive results due to
sialomucins.
János T Padra, Sara K. Lindén
Glycobiology - 2022 -
A Complex Connection Between the Diversity of Human Gastric Mucin O-Glycans, Helicobacter pylori Binding, Helicobacter Infection and
Fucosylation
Gurdeep Chahal, Médea Padra, Mattias Erhardsson, Chunsheng Jin, Macarena P Quintana-Hayashi, Vignesh Venkatakrishnan, János T Padra, Helena Stenbäck, A. Thorell, Niclas G. Karlsson, Sara K. Lindén
Molecular & Cellular Proteomics - 2022 -
Mucin O-glycosylation and pathogen binding ability differ between rainbow trout epithelial
sites
Kristina A Thomsson, John Benktander, Macarena P Quintana-Hayashi, Sinan Sharba, Sara K. Lindén
Fish & Shellfish Immunology - 2022 -
Streptococcus oralis Employs Multiple Mechanisms of Salivary Mucin Binding That Differ Between
Strains
Gurdeep Chahal, Macarena P Quintana-Hayashi, M. O. Gaytan, John Benktander, Médea Padra, S. J. King, Sara K. Lindén
Frontiers in Cellular and Infection Microbiology - 2022 -
Rainbow trout gastrointestinal mucus, mucin production, mucin glycosylation and response to
lipopolysaccharide
Sinan Sharba, Henrik Sundh, Kristina Sundell, John Benktander, Licínia Santos, George M. H. Birchenough, Sara K. Lindén
Fish and Shellfish Immunology - 2022 -
Mucin Binding to Moraxella catarrhalis During Airway Inflammation is Dependent on Sialic
Acid.
Médea Padra, John Benktander, János T Padra, Anders Andersson, Bettina Brundin, Sara Tengvall, Karin Christenson, Ingemar Qvarfordt, Robert Gad, Magnus Paulsson, Nikolaos Pournaras, Anders Lindén, Sara K. Lindén
American journal of respiratory cell and molecular biology - 2021 -
IL-36 Cytokines Promote Inflammation in the Lungs of Long-term
Smokers
Melissa A Kovach, Karlhans Che, Bettina Brundin, Anders Andersson, Helga Asgeirsdottir, Médea Padra, Sara K. Lindén, Ingemar Qvarfordt, Michael W Newstead, Theodore J Standiford, Anders Lindén
American journal of respiratory cell and molecular biology - 2021 -
Stress impairs skin barrier function and induces α2-3 linked n-acetylneuraminic acid and core 1 o-glycans on skin mucins in atlantic salmon, salmo
salar
John Benktander, Henrik Sundh, Kristina Sundell, Abarna V M Murugan, Vignesh Venkatakrishnan, János T Padra, Jelena Kolarevic, Bendik Fyhn Terjesen, Marnix Gorissen, Sara K. Lindén
International Journal of Molecular Sciences - 2021 -
Brachyspira species avidity to colonic mucins from pigs with and without brachyspira hyodysenteriae infection is species specific and varies between
strains
Macarena P Quintana-Hayashi, Mattias Erhardsson, Maxime Mahu, Vignesh Venkatakrishnan, Freddy Haesebrouck, Frank Pasmans, Sara K. Lindén
Infection and Immunity - 2021 -
Increased MUC1 plus a larger quantity and complex size for MUC5AC in the peripheral airway lumen of long-term tobacco
smokers
Médea Padra, Anders Andersson, B. Levanen, Pushpa Premaratne, Helga Asgeirsdottir, Sara Tengvall, Karin Christenson, Marit Stockfelt, S. Bozinovski, S. Yoshihara, A. S. Lantz, L. Palmberg, B. Dahlen, K. Larsson, Ingemar Qvarfordt, Sara K. Lindén, A. Linden
Clinical Science - 2020 -
In-Depth Study of Transmembrane Mucins in Association with Intestinal Barrier Dysfunction During the Course of T Cell Transfer and DSS-Induced
Colitis
T. Breugelmans, H. Van Spaendonk, J. G. De Man, H. U. De Schepper, A. Jauregui-Amezaga, E. Macken, Sara K. Lindén, I. Pintelon, J. P. Timmermans, B. Y. De Winter, A. Smet
Journal of Crohns & Colitis - 2020 -
Increased CD11b and Decreased CD62L in Blood and Airway Neutrophils from Long-Term Smokers with and without
COPD.
Marit Stockfelt, Karin Christenson, Anders Andersson, Lena Björkman, Médea Padra, Bettina Brundin, Koustav Ganguly, Helga Asgeirsdottir, Sara K. Lindén, Ingemar Qvarfordt, Johan Bylund, Anders Lindén
Journal of Innate Immunity - 2020 -
Smoking-associated increase in mucins 1 and 4 in human
airways
H. Merikallio, R. Kaarteenaho, Sara K. Lindén, Médea Padra, R. Karimi, C. X. Li, E. Lappi-Blanco, A. M. Wheelock, M. C. Skold
Respiratory research - 2020 -
Recombinant mucin-type proteins carrying LacdiNAc on differentO-glycan core chains fail to supportH.
pyloribinding
Yolanda H. Mthembu, Chunsheng Jin, Médea Padra, Jining Liu, J. O. Edlund, H. Y. Ma, János T Padra, S. Oscarson, T. Boren, Niclas G. Karlsson, Sara K. Lindén, Jan Holgersson
Molecular Omics - 2020 -
Gill Mucus and Gill Mucin O-glycosylation in Healthy and Amebic Gill Disease-Affected Atlantic
Salmon.
John Benktander, János T Padra, Ben Maynard, George M. H. Birchenough, Natasha A Botwright, Russel McCulloch, James W Wynne, Sinan Sharba, Kristina Sundell, Henrik Sundh, Sara K. Lindén
Microorganisms - 2020 -
Interleukin 4 induces rapid mucin transport, increases mucus thickness and quality and decreases colitis and Citrobacter rodentium in contact with epithelial
cells
Sinan Sharba, Nazanin Navabi, Médea Padra, Macarena P Quintana-Hayashi, Jenny K Gustafsson, Louis Szeponik, Vignesh Venkatakrishnan, A. Sjoling, Staffan Nilsson, Marianne Quiding-Järbrink, Malin E V Johansson, Sara K. Lindén
Virulence - 2019 -
Fish pathogen binding to mucins from Atlantic salmon and Arctic char differs in avidity and specificity and is modulated by fluid
velocity
János T Padra, Abarna V M Murugan, Kristina Sundell, Henrik Sundh, John Benktander, Sara K. Lindén
PLoS ONE - 2019 -
Role of Sialic Acid in Brachyspira hyodysenteriae Adhesion to Pig Colonic
Mucins
Macarena P Quintana-Hayashi, Vignesh Venkatakrishnan, F. Haesebrouck, Sara K. Lindén
Infection and Immunity - 2019 -
Genomics of host-pathogen interactions: challenges and opportunities across ecological and spatiotemporal
scales
K. Napflin, E. A. O'Connor, L. Becks, S. Bensch, V. A. Ellis, N. Hafer-Hahmand, Karin C. Harding, Sara K. Lindén, M. T. Olsen, J. Roved, T. B. Sackton, A. J. Shultz, Vignesh Venkatakrishnan, E. Videvall, H. Westerdahl, J. C. Winternitz
PeerJ - 2019 -
Mucin modified SPR interfaces for studying the effect of flow on pathogen binding to Atlantic salmon
mucins
János T Padra, Q. Pagneux, J. Bouckaert, R. Jijie, Henrik Sundh, R. Boukherroub, S. Szunerits, Sara K. Lindén
Biosensors and Bioelectronics - 2019 -
Effects of Size and Geographical Origin on Atlantic salmon, Salmo salar, Mucin O-Glycan
Repertoire
John Benktander, Vignesh Venkatakrishnan, János T Padra, Henrik Sundh, Kristina Sundell, Abarna V M Murugan, B. Maynard, Sara K. Lindén
Molecular & Cellular Proteomics - 2019 -
Helicobacter suis infection alters glycosylation and decreases the pathogen growth inhibiting effect and binding avidity of gastric
mucins
Médea Padra, Barbara Adamczyk, Bram Flahou, Mattias Erhardsson, Gurdeep Chahal, Annemieke Smet, Chunsheng Jin, Anders Thorell, Richard Ducatelle, Freddy Haesebrouck, Niclas G. Karlsson, Sara K. Lindén
Mucosal Immunology - 2019 -
Exploring the Arctic Charr Intestinal Glycome: Evidence of Increased N-Glycolylneuraminic Acid Levels and Changed Host-Pathogen Interactions in Response to
Inflammation
Vignesh Venkatakrishnan, János T Padra, Henrik Sundh, Kristina Sundell, Chunsheng Jin, M. Langeland, H. Carlberg, A. Vidakovic, T. Lundh, Niclas G. Karlsson, Sara K. Lindén
Journal of Proteome Research - 2019 -
Carbohydrate-Dependent and Antimicrobial Peptide Defence Mechanisms Against Helicobacter pylori
Infections
Médea Padra, John Benktander, K. Robinson, Sara K. Lindén
Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori - 2019 -
Formyl peptide receptor 2 orchestrates mucosal protection against Citrobacter rodentium
infection
Sinan Sharba, Vignesh Venkatakrishnan, Médea Padra, Malene Winther, Michael Gabl, Martina Sundqvist, J. Wang, Huamei Forsman, Sara K. Lindén
Virulence - 2019 -
The Farmed Atlantic Salmon (Salmo salar) Skin-Mucus Proteome and Its Nutrient Potential for the Resident Bacterial
Community
G. Minniti, S. R. Sandve, János T Padra, L. H. Hagen, Sara K. Lindén, P. B. Pope, M. O. Arntzen, G. Vaaje-Kolstad, Microbial Ecology V. P. Hill Mm
Genes - 2019 -
Helicobacter suis binding to carbohydrates on human and porcine gastric mucins and glycolipids occurs via two
modes
Médea Padra, Barbara Adamczyk, John Benktander, B. Flahou, Emma C Skoog, János T Padra, A. Smet, Chunsheng Jin, R. Ducatelle, Tore Samuelsson, F. Haesebrouck, Niclas G. Karlsson, Susann Teneberg, Sara K. Lindén
Virulence - 2018 -
Influence of the viscosity of healthy and diseased human mucins on the motility of Helicobacter
pylori
C. Su, Médea Padra, M. A. Constantino, Sinan Sharba, A. Thorell, Sara K. Lindén, R. Bansil
Scientific Reports - 2018 -
Evidence for a primate origin of zoonotic Helicobacter suis colonizing domesticated
pigs.
Bram Flahou, Mirko Rossi, Jaco Bakker, Jan Am Langermans, Edwin Heuvelman, Jay V Solnick, Miriam E Martin, Jani O'Rourke, Le Duc Ngoan, Nguyen Xuan Hoa, Masahiko Nakamura, Anders Øverby, Hidenori Matsui, Hiroyoshi Ota, Takehisa Matsumoto, Dennis L Foss, Laurice A Kopta, Oladipo Omotosho, Maria Pia Franciosini, Patrizia Casagrande Proietti, Aizhen Guo, Han Liu, Gabriela Borilova, Ana Paula Bracarense, Sara K. Lindén, Sofie De Bruyckere, Guangzhi Zhang, Chloë De Witte, Annemieke Smet, Frank Pasmans, Richard Ducatelle, Jukka Corander, Freddy Haesebrouck
The ISME journal - 2018 -
Mucus-Pathogen Interactions in the Gastrointestinal Tract of Farmed
Animals
Macarena P Quintana-Hayashi, Médea Padra, János T Padra, John Benktander, Sara K. Lindén
Microorganisms - 2018 -
BabA-mediated adherence of pediatric ulcerogenic H-pylori strains to gastric mucins at neutral and acidic
pH
Macarena P Quintana-Hayashi, R. Rocha, Médea Padra, A. Thorell, Chunsheng Jin, Niclas G. Karlsson, M. Roxo-Rosa, M. Oleastro, Sara K. Lindén
Virulence - 2018 -
Differentiation of Gastrointestinal Cell Lines by Culture in Semi-wet
Interface.
Macarena P Quintana-Hayashi, Sara K. Lindén
Epithelial Cell Culture. Baratta M. (red.) Methods in Molecular Biolog - 2018 -
Colonic levels of vasoactive intestinal peptide decrease during infection and exogenous VIP protects epithelial mitochondria against the negative effects of IFN gamma and TNF alpha induced during Citrobacter rodentium
infection
Arpan K. Maiti, Sinan Sharba, Nazanin Navabi, Sara K. Lindén
PLoS ONE - 2018 -
Bipolar lophotrichous Helicobacter suis combine extended and wrapped flagella bundles to exhibit multiple modes of
motility
M. A. Constantino, M. Jabbarzadeh, H. C. Fu, Z. L. Shen, J. G. Fox, F. Haesebrouck, Sara K. Lindén, R. Bansil
Scientific Reports - 2018 -
Aeromonas salmonicida Growth in Response to Atlantic Salmon Mucins Differs between Epithelial Sites, Is Governed by Sialylated and N-Acetylhexosamine-Containing O-Glycans, and Is Affected by
Ca2+
János T Padra, Henrik Sundh, Kristina Sundell, Vignesh Venkatakrishnan, Chunsheng Jin, Tore Samuelsson, Niclas G. Karlsson, Sara K. Lindén
Infection and Immunity - 2017
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