- Hem
- Om universitetet
- Hitta person
- Kristina Thomsson Hulthe
Kristina Thomsson Hulthe
Forskare
Sambio Core Facilities-
In Atlantic salmon skin infested with salmon lice, elevated seawater temperatures change gene expression and mucus glycosylation, which promotes pathogen
binding
Kristina Thomsson Hulthe, Lene Sveen, John Benktander, Binyam S. Dagnachew, Macarena Quintana Hayashi, Lill-Heidi Johansen, Mette W. Breiland, Celeste Jacq, Elisabeth Ytteborg, Sara Lindén
FISH & SHELLFISH IMMUNOLOGY - 2025 -
The barramundi (Lates calcarifer) mucus glycome is conserved across oral, skin and gill tissues but varies between
individuals
Kristina A Thomsson, John Benktander, Mattias Erhardsson, James W. Wynne, Richard S. Taylor, Sara K. Lindén
Fish and Shellfish Immunology - 2025 -
Navigating the maze of mass spectra: a machine-learning guide to identifying diagnostic ions in O-glycan
analysis
James Urban, Roman Joeres, Luc Thomes, Kristina A Thomsson, Daniel Bojar
ANALYTICAL AND BIOANALYTICAL CHEMISTRY - 2025 -
Glycoproteoforms of Osteoarthritis-associated Lubricin in Plasma and Synovial
Fluid
Ali Reza Afshari, Vincent Chang, Kristina A Thomsson, Jennifer Höglund, Elizabeth N. Browne, George Karadzhov, Keira E. Mahoney, Taryn M. Lucas, Valentina Rangel-Angarita, Henrik Ryberg, Kamlesh Gidwani, Kim Pettersson, Ola Rolfson, Lena Björkman, Thomas Eisler, Tannin A. Schmidt, Gregory D. Jay, Stacy A. Malaker, Niclas G. Karlsson
MOLECULAR & CELLULAR PROTEOMICS - 2025 -
Gilthead seabream mucus glycosylation is complex, differs between epithelial sites and carries unusual poly N-acetylhexosamine
motifs
Kristina A Thomsson, John Benktander, Socorro Toxqui-Rodriguez, M. Carla Piazzon, Sara K. Lindén
Fish and Shellfish Immunology - 2024 -
Altered O-Glycans in stimulated whole saliva from patients with primary Sjögren's syndrome and non-pSS
sicca
Sarah Kamounah, Kristina A Thomsson, Christiane Elisabeth Sorensen, Eric Paul Bennett, Niclas G. Karlsson, Anne Marie Lynge Pedersen
SCIENTIFIC REPORTS - 2024 -
UniCarb-DB: An MS/MS Experimental Glycomic Fragmentation
Database
Chunsheng Jin, Vignesh Venkatakrishnan, Kristina A Thomsson, Nobuyuki P. Aoki, Daisuke Shinmachi, Kiyoko F. Aoki-Kinoshita, Catherine A. Hayes, Frédérique Lisacek, Niclas G. Karlsson
Methods in molecular biology (Clifton, N.J.) - 2024 -
<i>In vitro</i> fish mucosal surfaces producing mucin as a model for studying host-pathogen
interactions
Macarena P Quintana-Hayashi, Kristina A. Thomsson Hulthe, Sara K. Lindén
PLOS ONE - 2024 -
Predicting glycan structure from tandem mass spectrometry via deep
learning
James Urban, Chunsheng Jin, Kristina A Thomsson, Niclas G. Karlsson, Callum M. Ives, Elisa Fadda, Daniel Bojar
NATURE METHODS - 2024 -
Characterization of intestinal O-glycome in reactive oxygen species
deficiency
Radka Saldova, Kristina A Thomsson, Hayden Wilkinson, Maitrayee Chatterjee, Ashish K. Singh, Niclas G. Karlsson, Ulla G. Knaus
PLOS ONE - 2024 -
Characterization of MdpS: an in-depth analysis of a MUC5B-degrading protease from Streptococcus
oralis
Fredrik Leo, Rolf Lood, Kristina A Thomsson, Jonas Nilsson, Gunnel Svensater, Claes Wickstrom
FRONTIERS IN MICROBIOLOGY - 2024 -
Protein N-glycosylation in the bronchoalveolar space differs between never-smokers and long-term smokers with and without
COPD.
Vignesh Venkatakrishnan, Kristina A Thomsson, Médea Padra, Anders Andersson, Bettina Brundin, Karin Christenson, Johan Bylund, Niclas G. Karlsson, Anders Lindén, Sara K. Lindén
Glycobiology - 2023 -
Identification of Novel Glycans in the Mucus Layer of Shark and Skate
Skin
Etty Bachar-Wikstrom, Kristina A Thomsson, Carina Sihlbom, Lisa Abbo, Haitham Tartor, Sara K. Lindén, Jakob D. Wikstrom
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2023 -
Truncated lubricin glycans in osteoarthritis stimulate the synoviocyte secretion of VEGFA, IL-8, and MIP-1α: Interplay between O-linked glycosylation and inflammatory
cytokines
Shan Huang, Kristina A Thomsson, Chunsheng Jin, H. Ryberg, N. Das, A. Struglics, Ola Rolfson, L. I. Björkman, T. Eisler, T. A. Schmidt, G. D. Jay, R. Krawetz, N. G. Karlsson
Frontiers in Molecular Biosciences - 2022 -
Mucin O-glycosylation and pathogen binding ability differ between rainbow trout epithelial
sites
Kristina A Thomsson, John Benktander, Macarena P Quintana-Hayashi, Sinan Sharba, Sara K. Lindén
Fish & Shellfish Immunology - 2022 -
Sulfation of O-glycans on Mucin-type Proteins From Serous Ovarian Epithelial
Tumors.
Kristina A Thomsson, Varvara Vitiazeva, Constantina Mateoiu, Chunsheng Jin, Jining Liu, Jan Holgersson, Birgitta Weijdegård, Karin Sundfeldt, Niclas G. Karlsson
Molecular & cellular proteomics : MCP - 2021 -
The O-Glycome of Human Nigrostriatal Tissue and Its Alteration in Parkinson's
Disease
H. Wilkinson, Kristina A Thomsson, A. L. Rebelo, M. Hilliard, A. Pandit, P. M. Rudd, Niclas G. Karlsson, R. Saldova
Journal of Proteome Research - 2021 -
Cathepsin g Degrades Both Glycosylated and Unglycosylated Regions of Lubricin, a Synovial
Mucin
Shan Huang, Kristina A Thomsson, Chunsheng Jin, Sally Alweddi, A. Struglics, Ola Rolfson, Lena Björkman, S. Kalamajski, T. A. Schmidt, G. D. Jay, R. Krawetz, Niclas G. Karlsson, T. Eisler
Scientific Reports - 2020 -
Decrease of core 2 O-glycans on synovial lubricin in osteoarthritis reduces galectin-3 mediated
crosslinking.
Sarah A. Flowers, Kristina A Thomsson, Liaqat Ali, Shan Huang, Yolanda H. Mthembu, Suresh C Regmi, Jan Holgersson, Tannin A Schmidt, Ola Rolfson, Lena Björkman, Martina Sundqvist, Anna Karlsson-Bengtsson, Gregory D Jay, Thomas Eisler, Roman Krawetz, Niclas G. Karlsson
The Journal of biological chemistry - 2020 -
Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut
microbiota
H. Nagao-Kitamoto, J. L. Leslie, S. Kitamoto, Chunsheng Jin, Kristina A Thomsson, M. G. Gillilland, P. Kuffa, Y. Goto, R. R. Jenq, C. Ishii, A. Hirayama, A. M. Seekatz, E. C. Martens, K. A. Eaton, J. Y. Kao, S. Fukuda, P. D. R. Higgins, Niclas G. Karlsson, V. B. Young, N. Kamada
Nature Medicine - 2020 -
Multiple Enzyme Approach for the Characterization of Glycan Modifications on the C-Terminus of the Intestinal
MUC2Mucin.
Sjoerd van der Post, Kristina A Thomsson, Gunnar C. Hansson
Journal of proteome research - 2014 -
Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific
distribution
Jessica Holmén Larsson, Kristina A Thomsson, Ana María Rodríguez-Piñeiro, Hasse Karlsson, Gunnar C. Hansson
American Journal of Physiology-Gastrointestinal and Liver Physiology - 2013 -
Detailed O-glycomics of the Muc2 mucin from colon of wild-type, core 1- and core 3-transferase-deficient mice highlights differences compared with human
MUC2.
Kristina A Thomsson, Jessica Holmén, Jonas Ångström, Malin E V Johansson, Lijun Xia, Gunnar C. Hansson
Glycobiology - 2012 -
Proteomic study of the mucin granulae in an intestinal goblet cell
model.
Ana María Rodríguez-Piñeiro, Sjoerd van der Post, Malin E V Johansson, Kristina A Thomsson, Alexey I Nesvizhskii, Gunnar C. Hansson
Journal of proteome research - 2012 -
Composition and functional role of the mucus layers in the
intestine.
Malin E V Johansson, Daniel Ambort, Thaher Pelaseyed, André Schütte, Jenny K Gustafsson, Anna Ermund, Durai B Subramani, Jessica Holmén Larsson, Kristina A Thomsson, Joakim H. Bergström, Sjoerd van der Post, Ana María Rodríguez-Piñeiro, Henrik Sjövall, Malin Bäckström, Gunnar C. Hansson
Cellular and Molecular Life Sciences - 2011 -
Identification and quantification of mucin
expression.
Kristina A Thomsson, Gunnar C. Hansson
Methods Mol. Biol. - 2011 -
Identification and quantification of mucin
expression
Kristina A Thomsson, Gunnar C. Hansson
Methods in molecular biology (Clifton, N.J.) - 2011 -
Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in
mice.
Jianxin Fu, Bo Wei, Tao Wen, Malin E V Johansson, Xiaowei Liu, Emily Bradford, Kristina A Thomsson, Samuel McGee, Lilah Mansour, Maomeng Tong, J Michael McDaniel, Thomas J Sferra, Jerrold R Turner, Hong Chen, Gunnar C. Hansson, Jonathan Braun, Lijun Xia
The Journal of clinical investigation - 2011 -
Comparison of methods for profiling O-glycosylation: Human Proteome Organisation Human Disease Glycomics/Proteome Initiative multi-institutional study of
IgA1.
Yoshinao Wada, Anne Dell, Stuart M Haslam, Bérangère Tissot, Kévin Canis, Parastoo Azadi, Malin Bäckström, Catherine E Costello, Gunnar C. Hansson, Yoshiyuki Hiki, Mayumi Ishihara, Hiromi Ito, Kazuaki Kakehi, Niclas G. Karlsson, C E Hayes, Koichi Kato, Nana Kawasaki, Kay-Hooi Khoo, Kunihiko Kobayashi, Daniel Kolarich, Akihiro Kondo, Carlito Lebrilla, Miyako Nakano, Hisashi Narimatsu, Jan Novak, Milos V Novotny, Erina Ohno, Nicolle H Packer, Elizabeth Palaima, Matthew B Renfrow, Michiko Tajiri, Kristina A Thomsson, Hirokazu Yagi, Shin-Yi Yu, Naoyuki Taniguchi
Molecular & cellular proteomics - 2010 -
Enhanced Detection of Sialylated and Sulfated Glycans with Negative Ion Mode Nanoliquid Chromatography/Mass Spectrometry at High
pH.
Kristina A Thomsson, Malin Bäckström, Jessica Holmén Larsson, Gunnar C. Hansson, Hasse Karlsson
Analytical chemistry - 2010 -
Cervical mucins carry alpha(1,2)fucosylated glycans that partly protect from experimental vaginal
candidiasis.
Steven E Domino, Elizabeth A Hurd, Kristina A Thomsson, David M Karnak, Jessica Holmén Larsson, Elisabeth Thomsson, Malin Bäckström, Gunnar C. Hansson
Glycoconjugate journal - 2009 -
High-throughput and high-sensitivity nano-LC/MS and MS/MS for O-glycan
profiling.
Hasse Karlsson, Jessica Holmén Larsson, Kristina A Thomsson, Iris van Dijk Härd, Malin Bäckström, Gunnar C. Hansson
Methods in molecular biology (Clifton, N.J.) - 2009 -
Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp
protein.
Malin E V Johansson, Kristina A Thomsson, Gunnar C. Hansson
Journal of proteome research - 2009 -
Sensitive liquid chromatography-electrospray mass spectrometry allows for the analysis of the O-glycosylation of immunoprecipitated proteins from cells or tissues: application to MUC1 glycosylation in
cancer.
Malin Bäckström, Kristina A Thomsson, Hasse Karlsson, Gunnar C. Hansson
Journal of proteome research - 2009 -
Salivary MUC7 is a major carrier of blood group I type O-linked oligosaccharides serving as the scaffold for sialyl Lewis
x.
Niclas G. Karlsson, Kristina A Thomsson
Glycobiology - 2009 -
Large scale identification of proteins, mucins, and their O-glycosylation in the endocervical mucus during the menstrual
cycle.
Ylva Andersch-Björkman, Kristina A Thomsson, Jessica Holmén Larsson, Erling Ekerhovd, Gunnar C. Hansson
Molecular & cellular proteomics : MCP - 2007 -
MUC5B glycosylation in human saliva reflects blood group and secretor
status.
Kristina A Thomsson, Benjamin L Schulz, Nicolle H Packer, Niclas G. Karlsson
Glycobiology - 2005 -
Intestinal mucins from cystic fibrosis mice show increased fucosylation due to an induced Fucalpha1-2
glycosyltransferase.
Kristina A Thomsson, Marina Hinojosa-Kurtzberg, Karin A Axelsson, Steven E Domino, John B Lowe, Sandra J Gendler, Gunnar C. Hansson
The Biochemical journal - 2002 -
The salivary mucin MG1 (MUC5B) carries a repertoire of unique oligosaccharides that is large and
diverse.
Kristina A Thomsson, Akraporn Prakobphol, Hakon Leffler, Molakala S Reddy, Michael J Levine, Susan J Fisher, Gunnar C. Hansson
Glycobiology - 2002 -
Analytical approaches to the study of mucin
glycosylation
Kristina A Thomsson
2000 -
Sequencing of sulfated oligosaccharides from mucins by liquid chromatography and electrospray ionization tandem mass
spectrometry.
Kristina A Thomsson, H Karlsson, Gunnar C. Hansson
Analytical chemistry - 2000 -
Liquid chromatography-electrospray mass spectrometry as a tool for the analysis of sulfated oligosaccharides from mucin
glycoproteins.
Kristina A Thomsson, Niclas G. Karlsson, Gunnar C. Hansson
Journal of chromatography. A - 1999 -
Different O-glycosylation of respiratory mucin glycopeptides from a patient with cystic
fibrosis.
Kristina A Thomsson, I Carlstedt, Niclas G. Karlsson, Hasse Karlsson, Gunnar C. Hansson
Glycoconjugate journal - 1998 -
Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand
activity.
A Prakobphol, Kristina A Thomsson, Gunnar C. Hansson, S D Rosen, M S Singer, N J Phillips, K F Medzihradszky, A L Burlingame, H Leffler, S J Fisher
Biochemistry - 1998