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Maria Magnusson
Senior Lecturer
Institute of Biomedicine-
Exposure of Colon-Derived Epithelial Monolayers to Fecal Luminal Factors from Patients with Colon Cancer and Ulcerative Colitis Results in Distinct Gene Expression
Patterns
Maria K Magnusson, Anna Bas-Forsberg, Alexandra Verveda, Maria Sapnara, Julie Lorent, Otto Savolainen, Yvonne Wettergren, Hans Strid, Magnus Simrén, Lena Öhman
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2024 -
Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel
disease
Samira Salihovic, Niklas Nystrom, Charlotte Bache-Wiig Mathisen, Robert Kruse, Christine Olbjorn, Svend Andersen, Alexandra J. Noble, Maria Dorn-Rasmussen, Igor Bazov, Gori Perminow, Randi Opheim, Trond Espen Detlie, Gert Huppertz-Hauss, Charlotte R. H. Hedin, Marie Carlson, Lena Öhman, Maria K Magnusson, Asa V. Keita, Johan D. Soderholm, Mauro D'Amato, Matej Oresic, Vibeke Wewer, Jack Satsangi, Carl Marten Lindqvist, Johan Burisch, Holm H. Uhlig, Dirk Repsilber, Tuulia Hyotylainen, Marte Lie Hoivik, Jonas Halfvarson
NATURE COMMUNICATIONS - 2024 -
Temporal stability of fecal metabolomic profiles in irritable bowel
syndrome
Cristina Iribarren, Otto Savolainen, Maria Sapnara, Hans Törnblom, Magnus Simrén, Maria K Magnusson, Lena Öhman
Neurogastroenterology and Motility - 2024 -
Fecal Supernatants from Patients with Crohn's Disease Induce Inflammatory Alterations in M2 Macrophages and
Fibroblasts
Frida Gorreja, Mia Bendix, Stephen T. A. Rush, Lujain Maasfeh, Otto Savolainen, Anders Dige, Jorgen Agnholt, Lena Öhman, Maria K Magnusson
CELLS - 2024 -
Fecal Biomarkers of Neutrophil and Eosinophil Origin Reflect the Response to Biological Therapy and Corticosteroids in Patients With Inflammatory Bowel
Disease
Maria Ling Lundström, Christer Peterson, Maria Lampinen, Charlotte R.H. Hedin, Åsa V. Keita, Robert Kruse, Maria K Magnusson, Carl Mårten Lindqvist, Dirk Repsilber, Mauro D'Amato, Henrik Hjortswang, Hans Strid, Anders Rönnblom, Johan D. Söderholm, Lena Öhman, Per Venge, Jonas Halfvarson, Marie Carlson
Clinical and translational gastroenterology - 2023 -
Combinatory analysis of immune cell subsets and tumor-specific genetic variants predict clinical response to PD-1 blockade in patients with non-small cell lung
cancer
Nikita Dutta, Anna Rohlin, Ella A Eklund, Maria K Magnusson, Frida Nilsson, Levent Akyürek, Per Torstensson, Volkan I. Sayin, Anna Lundgren, Andreas Hallqvist, Sukanya Raghavan
Frontiers in Oncology - 2023 -
Differences in Metabolite Composition of Aloe barbadensis Mill. Extracts Lead to Differential Effects on Human Blood T Cell Activity In
Vitro.
Bani Ahluwalia, Maria K Magnusson, Fredrik Larsson, Otto Savolainen, Alastair B Ross, Lena Öhman
Molecules (Basel, Switzerland) - 2022 -
Downregulated Mucosal Autophagy, Alpha Kinase-1 and IL-17 Signaling Pathways in Active and Quiescent Ulcerative
Colitis.
Luiza Moraes Holst, Jonas Halfvarson, Marie Carlson, Charlotte Hedin, Robert Kruse, Carl Mårten Lindqvist, Daniel Bergemalm, Sven Almér, Francesca Bresso, Maria Ling Lundström, Dirk Repsilber, Mauro D'Amato, Åsa Keita, Henrik Hjortswang, Johan Söderholm, Johanna Sundin, Hans Törnblom, Magnus Simrén, Hans Strid, Maria K Magnusson, Lena Öhman
Clinical and experimental gastroenterology - 2022 -
Fecal Luminal Factors from Patients with Gastrointestinal Diseases Alter Gene Expression Profiles in Caco-2 Cells and
Colonoids
Luiza Moraes Holst, Cristina Iribarren, Maria Sapnara, O. Savolainen, Hans Törnblom, Yvonne Wettergren, H. Strid, Magnus Simrén, Maria K Magnusson, Lena Öhman
International Journal of Molecular Sciences - 2022 -
Randomised controlled trial: effects of gluten-free diet on symptoms and the gut microenvironment in irritable bowel
syndrome
Joost Algera, Maria K Magnusson, Lena Öhman, Stine Störsrud, Magnus Simrén, Hans Törnblom
Alimentary Pharmacology and Therapeutics - 2022 -
Fecal luminal factors from patients with irritable bowel syndrome induce distinct gene expression of
colonoids
Cristina Iribarren, Sofia Nordlander, Johanna Sundin, Stefan Isaksson, O. Savolainen, Hans Törnblom, Maria K Magnusson, Magnus Simrén, Lena Öhman
Neurogastroenterology and Motility - 2022 -
MEFV and NLRP3 Inflammasome Expression Is Attributed to Immature Macrophages and Correlates with Serum Inflammatory Proteins in Crohn ' s Disease
Patients
Frida Gorreja, Charles Caër, Stephen T.A Rush, Sophia K. Forsskål, Anetta Härtlova, Maria K Magnusson, Elinor Bexe-Lindskog, Lars Börjesson, Mattias Block, Mary Jo Wick
Inflammation - 2022 -
Impaired Luminal Control of Intestinal Macrophage Maturation in Patients With Ulcerative Colitis During
Remission
Lujain Maasfeh, Anetta Härtlova, Stefan Isaksson, Johanna Sundin, G. Mavroudis, O. Savolainen, H. Strid, Lena Öhman, Maria K Magnusson
Cellular and Molecular Gastroenterology and Hepatology - 2021 -
TREM-1+ Macrophages Define a Pathogenic Cell Subset in the Intestine of Crohn's Disease
Patients
Charles Caër, Frida Gorreja, Sophia Forsskåhl, Siggeir Brynjolfsson, Louis Szeponik, Maria K Magnusson, Lars G. Börjesson, Mattias Block, Elinor Bexe-Lindskog, Mary Jo Wick
Journal of Crohn's & colitis - 2021 -
Aloe barbadensis Mill. extract improves symptoms in IBS patients with diarrhoea: post hoc analysis of two randomized double-blind controlled
studies
Bani Ahluwalia, Maria K Magnusson, Lena Böhn, Stine Störsrud, F. Larsson, Lena Öhman, Magnus Simrén
Therapeutic Advances in Gastroenterology - 2021 -
Fecal microbiota dynamics during disease activity and remission in newly diagnosed and established ulcerative
colitis
Lena Öhman, A. Lasson, Anna Strömbeck, Stefan Isaksson, Marcus Hesselmar, Magnus Simrén, H. Strid, Maria K Magnusson
Scientific Reports - 2021 -
The Effects of Human Milk Oligosaccharides on Gut Microbiota, Metabolite Profiles and Host Mucosal Response in Patients with Irritable Bowel
Syndrome
Cristina Iribarren, Maria K Magnusson, L. K. Vigsnaes, Imran Aziz, I. D. Amundsen, T. Suligoj, N. Juge, Piyush Patel, Maria Sapnara, L. Johnsen, N. Sorensen, Johanna Sundin, Hans Törnblom, Magnus Simrén, Lena Öhman
Nutrients - 2021 -
A Distinct Faecal Microbiota and Metabolite Profile Linked to Bowel Habits in Patients with Irritable Bowel
Syndrome
Bani Ahluwalia, Cristina Iribarren, Maria K Magnusson, Johanna Sundin, Egbert Clevers, O. Savolainen, A. B. Ross, Hans Törnblom, Magnus Simrén, Lena Öhman
Cells - 2021 -
Impaired Butyrate Induced Regulation of T Cell Surface Expression of CTLA-4 in Patients with Ulcerative
Colitis
Maria K Magnusson, A. Vidal, Lujain Maasfeh, Stefan Isaksson, R. Malhotra, H. K. Olsson, Lena Öhman
International Journal of Molecular Sciences - 2021 -
Systemic Inflammatory Protein Profiles Distinguish Irritable Bowel Syndrome (IBS) and Ulcerative Colitis, Irrespective of Inflammation or IBS-Like
Symptoms.
Luiza Moraes, Maria K Magnusson, Georgios Mavroudis, Annikka Polster, Börje Jonefjäll, Hans Törnblom, Johanna Sundin, Magnus Simrén, Hans Strid, Lena Öhman
Inflammatory bowel diseases - 2020 -
Human milk oligosaccharide supplementation in irritable bowel syndrome patients: A parallel, randomized, double-blind, placebo-controlled
study
Cristina Iribarren, Hans Törnblom, Imran Aziz, Maria K Magnusson, Johanna Sundin, L. K. Vigsnaes, I. D. Amundsen, B. McConnell, D. Seitzberg, Lena Öhman, Magnus Simrén
Neurogastroenterology and Motility - 2020 -
Fecal microbiota composition is linked to the postoperative disease course in patients with Crohn's
disease
Anna Strömbeck, Anders Lasson, H. Strid, Johanna Sundin, P. O. Stotzer, Magnus Simrén, Maria K Magnusson, Lena Öhman
BMC Gastroenterology - 2020 -
Randomized clinical trial: Effects of Aloe barbadensis Mill. extract on symptoms, fecal microbiota and fecal metabolite profiles in patients with irritable bowel
syndrome
Bani Ahluwalia, Maria K Magnusson, Lena Böhn, Stine Störsrud, F. Larsson, O. Savolainen, A. Ross, Magnus Simrén, Lena Öhman
Neurogastroenterology and Motility - 2020 -
The Anti-inflammatory Immune Regulation Induced by Butyrate Is Impaired in Inflamed Intestinal Mucosa from Patients with Ulcerative
Colitis.
Maria K Magnusson, Stefan Isaksson, Lena Öhman
Inflammation - 2020 -
The frequency of circulating integrin alpha 4 beta 7(+) cells correlates with protection against Helicobacter pylori infection in immunized
mice
S. Akter, Frida Jeverstam, Anna Lundgren, Maria K Magnusson, A. Walduck, F. Qadri, T. R. Bhuiyan, Sukanya Raghavan
Helicobacter - 2019 -
A distinct gut microbiota composition in patients with ankylosing spondylitis is associated with increased levels of fecal
calprotectin
Eva Klingberg, Maria K Magnusson, Hans Strid, Anna Deminger, Arne Ståhl, Johanna Sundin, Magnus Simrén, Hans Carlsten, Lena Öhman, Helena Forsblad d'Elia
Arthritis Research & Therapy - 2019 -
Mucosal and Systemic Immune Profiles Differ During Early and Late Phases of the Disease in Patients With Active Ulcerative
Colitis
Georgios Mavroudis, Maria K Magnusson, Stefan Isaksson, Johanna Sundin, Magnus Simrén, Lena Öhman, Hans Strid
Journal of Crohns & Colitis - 2019 -
Osteoporosis and skeletal dysplasia caused by pathogenic variants in
SGMS2
M. Pekkinen, P. A. Terhal, L. D. Botto, Petra Henning, R. E. Makitie, P. Roschger, A. Jain, M. Kol, M. A. Kjellberg, E. P. Paschalis, K. van Lassen, M. Murray, P. Bayrak-Toydemir, Maria K Magnusson, J. Jans, M. Kausar, J. C. Carey, P. Somerharju, Ulf H Lerner, V. M. Olkkonen, K. Klaushofer, J. C. M. Holthuis, O. Makitie
Jci Insight - 2019 -
Altered intestinal antibacterial gene expression response profile in irritable bowel syndrome is linked to bacterial composition and immune
activation
Sean Bennet, Johanna Sundin, Maria K Magnusson, H. Strid, J. Tap, M. Derrien, B. Le Neve, J. Dore, Hans Törnblom, Magnus Simrén, Lena Öhman
Neurogastroenterology and Motility - 2018 -
Immunopathogenesis of inflammatory bowel disease and mechanisms of biological
therapies
Bani Ahluwalia, Luiza Moraes, Maria K Magnusson, Lena Öhman
Scandinavian Journal of Gastroenterology - 2018 -
High-dose vitamin D3 supplementation decreases the number of colonic CD103+ dendritic cells in healthy
subjects.
Nina Friis Bak, M Bendix, S Hald, L Reinert, Maria K Magnusson, J Agnholt
European journal of nutrition - 2018 -
Activated T follicular helper-like cells are released into blood after oral vaccination and correlate with vaccine specific mucosal B-cell
memory
Ana Cardeno, Maria K Magnusson, Marianne Quiding-Järbrink, Anna Lundgren
Scientific Reports - 2018 -
Mucosal immune system of the gastrointestinal tract: maintaining balance between the good and the
bad
Bani Ahluwalia, Maria K Magnusson, Lena Öhman
Scandinavian Journal of Gastroenterology - 2017 -
The Mucosal Antibacterial Response Profile and Fecal Microbiota Composition Are Linked to the Disease Course in Patients with Newly Diagnosed Ulcerative
Colitis
Maria K Magnusson, Hans Strid, Stefan Isaksson, Magnus Simrén, Lena Öhman
Inflammatory Bowel Diseases - 2017 -
An Antibody Against Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) Dampens Proinflammatory Cytokine Secretion by Lamina Propria Cells from Patients with
IBD.
Siggeir Fannar Brynjólfsson, Maria K Magnusson, Philip L Kong, Teis Jensen, Joseph L Kuijper, Katarina Håkansson, Christine B Read, Vibeke W Stennicke, Henrik Sjövall, Mary Jo Wick
Inflammatory bowel diseases - 2016 -
Anti-TNF Therapy Response in Patients with Ulcerative Colitis Is Associated with Colonic Antimicrobial Peptide Expression and Microbiota
Composition.
Maria K Magnusson, Hans Strid, Maria Sapnara, Anders Lasson, Antal Bajor, Kjell-Arne Ung, Lena Öhman
Journal of Crohn's & colitis - 2016 -
Reduced numbers of mucosal DRint macrophages and increased numbers of CD103(+) dendritic cells during anti-TNF-alpha treatment in patients with Crohn's
disease
A. Dige, Maria K Magnusson, Lena Öhman, C. L. Hvas, J. Kelsen, Mary Jo Wick, J. Agnholt
Scandinavian Journal of Gastroenterology - 2016 -
Effects of Aloe barbadensis Mill. extract (AVH200 (R)) on human blood T cell activity in
vitro
Bani Ahluwalia, Maria K Magnusson, Stefan Isaksson, Fredrik Larsson, Lena Öhman
Journal of Ethnopharmacology - 2016 -
Macrophage and dendritic cell subsets in IBD: ALDH cells are reduced in colon tissue of patients with ulcerative colitis regardless of
inflammation
Maria K Magnusson, Siggeir Fannar Brynjólfsson, A. Dige, H. Uronen-Hansson, Lars Börjesson, J. L. Bengtsson, S. Gudjonsson, Lena Öhman, J. Agnholt, Henrik Sjövall, W. W. Agace, Mary Jo Wick
Mucosal Immunology - 2016 -
Global mucosal and serum cytokine profile in patients with ulcerative colitis undergoing anti-TNF
therapy
Rahil Dahlén, Maria K Magnusson, Antal Bajor, A. Lasson, Kjell-Arne Ung, Hans Strid, Lena Öhman
Scandinavian Journal of Gastroenterology - 2015 -
Cultured blood T-cell responses predict anti-TNF therapy response in patients with ulcerative
colitis
Maria K Magnusson, Hans Strid, Stefan Isaksson, Antal Bajor, Anders Lasson, Kjell-Arne Ung, Lena Öhman
Alimentary Pharmacology & Therapeutics - 2015 -
Response to infliximab therapy in ulcerative colitis is associated with decreased monocyte activation, reduced CCL2 expression and downregulation of Tenascin
C.
Maria K Magnusson, Hans Strid, Stefan Isaksson, Antal Bajor, Anders Lasson, Kjell-Arne Ung, Lena Öhman
Journal of Crohn's & colitis - 2015 -
Spontaneous colitis in Muc2-deficient mice reflects clinical and cellular features of active ulcerative
colitis.
Ulf Alexander Wenzel, Maria K Magnusson, Anna Rydström, Caroline Jonstrand, Julia Hengst, Malin E V Johansson, Anna Velcich, Lena Öhman, Hans Strid, Henrik Sjövall, Gunnar C. Hansson, Mary Jo Wick
PloS one - 2014 -
The unsaponifiable fraction of extra virgin olive oil promotes apoptosis and attenuates activation and homing properties of T cells from patients with inflammatory bowel
disease
A. Cardeno, Maria K Magnusson, Hans Strid, C. A. de la Lastra, M. Sanchez-Hidalgo, Lena Öhman
Food Chemistry - 2014 -
CD25 and TNF receptor II reflect early primary response to infliximab therapy in patients with ulcerative
colitis
Maria K Magnusson, Rahil Dahlén, Hans Strid, Stefan Isaksson, Magnus Simrén, Anders Lasson, Antal Bajor, Kjell-Arne Ung, Lena Öhman
United European Gastroenterology Journal - 2013 -
Infliximab Inhibits Activation and Effector Functions of Peripheral Blood T Cells in vitro from Patients with Clinically Active Ulcerative
Colitis
Rahil Dahlén, Hans Strid, Anna Lundgren, Stefan Isaksson, Sukanya Raghavan, Maria K Magnusson, Magnus Simrén, Henrik Sjövall, Lena Öhman
Scandinavian Journal of Immunology - 2013 -
A transductionally retargeted adenoviral vector for virotherapy of her2/neu-expressing prostate
cancer
Maria K Magnusson, R. Kraaij, R. M. Leadley, C. M.A. De Ridder, W. M. Van Weerden, K. A.J. Van Schie, M. Van Der Kroeg, R. C. Hoeben, N. J. Maitland, L. Lindholm
Human Gene Therapy - 2012 -
Intestinal dendritic cell and macrophage subsets: Tipping the balance to Crohn's
disease?
Maria K Magnusson, Mary Jo Wick
Eur. J. Microbiol. Immunol. - 2011 -
Toxic activity of the CdtB component of Haemophilus ducreyi cytolethal distending toxin expressed from an adenovirus 5
vector
Catharina Wising, Maria K Magnusson, Karin Ahlman, Leif Lindholm, Teresa Lagergård
APMIS - 2010 -
Adenovirus 5-fiber 35 chimeric vector mediates efficient apical correction of the CFTR defect in cystic fibrosis primary airway
epithelia.
Ophélia Granio, Katherine Ashbourne Excoffon, Petra Henning, Patricia Melin, Caroline Norez, Gaelle Gonzalez, Philip Karp, Maria K Magnusson, Nagy Habib, Leif Lindholm, Frédéric Becq, Pierre Boulanger, Joseph Zabner, Saw See Hong
Human gene therapy - 2010 -
A lentiviral vector-based adenovirus fiber-pseudotyping approach for expedited functional assessment of candidate retargeted
fibers.
Taco G Uil, Jeroen de Vrij, Jort Vellinga, Martijn J W E Rabelink, Steve J Cramer, On Ying A Chan, Margherita Pugnali, Maria K Magnusson, Leif Lindholm, Pierre Boulanger, Rob C Hoeben
The journal of gene medicine - 2009 -
Re-targeted adenovirus vectors with dual specificity; binding specificities conferred by two different Affibody molecules in the
fiber.
Susanna Myhre, Petra Henning, M Friedman, S Ståhl, Leif Lindholm, Maria K Magnusson
Gene therapy - 2009 -
Novel strategies in tailoring human adenovirus into therapeutic cencer gene therapy
vectors
Leif Lindholm, Petra Henning, Maria K Magnusson
Future Virology - 2008 -
Protein crystals in Adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional
analysis.
Laure Franqueville, Petra Henning, Maria K Magnusson, Emmanuelle Vigne, Guy Schoehn, Maria E Blair-Zajdel, Nagy Habib, Leif Lindholm, G Eric Blair, Saw See Hong, Pierre Boulanger
PLoS ONE - 2008 -
Adenovirus 5 vector genetically re-targeted by an Affibody molecule with specificity for tumor antigen
HER2/neu.
Maria K Magnusson, Petra Henning, Susanna Myhre, M Wikman, T G Uil, M Friedman, S S Hong, R C Hoeben, N A Habib, S Ståhl, P Boulanger, Leif Lindholm, Karin Andersson
Cancer gene therapy - 2007 -
Adenovirus type 5 fiber knob domain has a critical role in fiber protein synthesis and
encapsidation
Petra Henning, Emma Lundgren, Mattias Carlsson, Karolin Frykholm, Jenny Johannisson, Maria K Magnusson, Erika Tång, Laure Franqueville, Saw See Hong, Leif Lindholm, Pierre Boulanger
JOURNAL OF GENERAL VIROLOGY - 2006 -
The maturation of murine dendritic cells induced by human adenovirus is mediated by the fiber knob
domain.
Valérie Molinier-Frenkel, Armelle Prévost-Blondel, Saw-See Hong, Renée Lengagne, Sarah Boudaly, Maria K Magnusson, Pierre Boulanger, Jean-Gérard Guillet
The Journal of biological chemistry - 2003 -
Adenovirus stripping: a versatile method to generate adenovirus vectors with new cell target
specificity.
Saw See Hong, Maria K Magnusson, Petra Henning, Leif Lindholm, Pierre A Boulanger
Molecular therapy : the journal of the American Society of Gene Therapy - 2003 -
Genetic modification of adenovirus 5 tropism by a novel class of ligands based on a three-helix bundle scaffold derived from staphylococcal protein
A.
Petra Henning, Maria K Magnusson, E Gunneriusson, S S Hong, P Boulanger, P-A Nygren, Leif Lindholm
Human gene therapy - 2002 -
Genetic retargeting of adenovirus vectors: functionality of targeting ligands and their influence on virus
viability.
Maria K Magnusson, Saw See Hong, Petra Henning, Pierre Boulanger, Leif Lindholm
The journal of gene medicine - 2002 -
Genetic re-targeting of adenoviral vectors for gene therapy
applications
Maria K Magnusson
2002 -
Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the
fiber.
Maria K Magnusson, S S Hong, P Boulanger, L Lindholm
Journal of virology - 2001