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- Anetta Härtlova
Anetta Härtlova
Senior Lecturer
Department of Microbiology and Immunology-
Therapeutic Potential of STE20-Type Kinase STK25 Inhibition for the Prevention and Treatment of Metabolically Induced Hepatocellular
Carcinoma
Ying Xia, Mara Caputo, Emma Andersson, Bernice Asiedu, Jingjing Zhang, Wei Hou, Manoj Amrutkar, Emmelie Cansby, Nadia Gul, Anne Gemmink, Caitlyn Myers, Mariam Aghajan, Sheri Booten, Andrew J. Hoy, Anetta Härtlova, Per Lindahl, Anders Ståhlberg, Gert Schaart, Matthijs K. C. Hesselink, Andreas Peter, Sue Murray, Margit Mahlapuu
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY - 2025 -
Loss of Lamin A leads to the nuclear translocation of AGO2 and compromised RNA
interference
Vivian Lobo, Iwona Nowak, Carola Fernandez, Ana Iris Correa Muler, Jakub O. Westholm, Hsiang-Chi Huang, Ivo Fabrik, Hang Thuy Huynh, Evgeniia Shcherbinina, Melis Poyraz, Anetta Härtlova, Daniel Benhalevy, Davide Angeletti, Aishe A. Sarshad
NUCLEIC ACIDS RESEARCH - 2024 -
Adipose tissue macrophage dysfunction is associated with a breach of vascular integrity in
NASH
Markus Boesch, Andreas Lindhorst, Rita Feio-Azevedo, Paola Brescia, Alessandra Silvestri, Matthias Lannoo, Ellen Deleus, Joris Jaekers, Halit Topal, Baki Topal, Tessa Ostyn, Marie Wallays, Lena Smets, Lukas Van Melkebeke, Anetta Härtlova, Tania Roskams, Pierre Bedossa, Jef Verbeek, Olivier Govaere, Sven Francque, Alejandro Sifrim, Thierry Voet, Maria Rescigno, Martin Gericke, Hannelie Korf, Schalk van der Merwe
Journal of Hepatology - 2024 -
Assessing the Phagosome Proteome by Quantitative Mass
Spectrometry
Maria Emilia Dueñas, José Luis Marín-Rubio, Julien Peltier-Heap, Anetta Härtlova, Matthias Trost
Methods in molecular biology (Clifton, N.J.) - 2023 -
Excessive copper impairs intrahepatocyte trafficking and secretion of selenoprotein
P.
Maria Schwarz, Caroline E Meyer, Alina Löser, Kristina Lossow, Julian Hackler, Christiane Ott, Susanne Jäger, Isabelle Mohr, Ella A Eklund, Angana A. H. Patel, Nadia Gul, Samantha Alvarez, Ilayda Altinonder, Clotilde Wiel, Maria Maares, Hajo Haase, Anetta Härtlova, Tilman Grune, Matthias B Schulze, Tanja Schwerdtle, Uta Merle, Hans Zischka, Volkan I. Sayin, Lutz Schomburg, Anna P Kipp
Nature communications - 2023 -
Lung macrophages utilize unique cathepsin K-dependent phagosomal machinery to degrade intracellular
collagen
Ivo Fabrik, Orsolya Bilkei-Gorzo, Maria Öberg, Daniela Fabrikova, Johannes Fuchs, Carina Sihlbom, M. Goransson, Anetta Härtlova
Life Science Alliance (LSA) - 2023 -
Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer
retina
M. Kurzawa-Akanbi, P. Whitfield, F. Burte, P. M. Bertelli, V. Pathak, M. Doherty, B. Hilgen, L. Gliaudelyte, M. Platt, R. Queen, J. Coxhead, A. Porter, Maria Öberg, Daniela Fabrikova, T. Davey, C. S. Beh, M. Georgiou, J. Collin, V. Boczonadi, Anetta Härtlova, M. Taggart, J. Al-Aama, V. I. Korolchuk, C. M. Morris, J. Guduric-Fuchs, D. H. Steel, R. J. Medina, L. Armstrong, M. Lako
Journal of Extracellular Vesicles - 2022 -
The E3 ubiquitin ligase RNF115 regulates phagosome maturation and host response to bacterial
infection
Orsolya Bilkei-Gorzo, T. Heunis, J. L. Marin-Rubio, F. R. Cianfanelli, B. B. A. Raymond, J. Inns, Daniela Fabrikova, J. Peltier, F. Oakley, R. Schmid, Anetta Härtlova, M. Trost
EMBO Journal - 2022 -
The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I
axis
S. F. Erttmann, P. Swacha, K. M. Aung, B. Brindefalk, H. Jiang, Anetta Härtlova, B. E. Uhlin, S. N. Wai, N. O. Gekara
Immunity - 2022 -
MEFV and NLRP3 Inflammasome Expression Is Attributed to Immature Macrophages and Correlates with Serum Inflammatory Proteins in Crohn ' s Disease
Patients
Frida Gorreja, Charles Caër, Stephen T.A Rush, Sophia K. Forsskål, Anetta Härtlova, Maria K Magnusson, Elinor Bexe-Lindskog, Lars Börjesson, Mattias Block, Mary Jo Wick
Inflammation - 2022 -
Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body
disorders
M. Kurzawa-Akanbi, S. Tammireddy, Ivo Fabrik, M. K. Doherty, R. Heap, Björn Marcus Burmann, Irena Matečko-Burmann, M. Trost, J. M. Lucocq, A. V. Gherman, G. Fairfoul, P. Singh, F. Burte, A. Green, I. G. McKeith, P. D. Whitfield, Anetta Härtlova, C. M. Morris
Acta Neuropathologica - 2021 -
Impaired Luminal Control of Intestinal Macrophage Maturation in Patients With Ulcerative Colitis During
Remission
Lujain Maasfeh, Anetta Härtlova, Stefan Isaksson, Johanna Sundin, G. Mavroudis, O. Savolainen, H. Strid, Lena Öhman, Maria K Magnusson
Cellular and Molecular Gastroenterology and Hepatology - 2021 -
TPL-2 kinase induces phagosome acidification to promote macrophage killing of
bacteria
F. Breyer, Anetta Härtlova, T. Thurston, H. R. Flynn, P. Chakravarty, J. Janzen, J. Peltier, T. Heunis, A. P. Snijders, M. Trost, S. C. Ley
Embo Journal - 2021 -
The role of innate immunity and inflammation in Parkinson ' s
disease
Maria Öberg, Ivo Fabrik, Daniela Fabrikova, Nina Zehetner, Anetta Härtlova
Scandinavian Journal of Immunology - 2021 -
Simvastatin therapy attenuates memory deficits that associate with brain monocyte infiltration in chronic
hypercholesterolemia
Nicholas Don-Doncow, Lotte Vanherle, Frank Matthes, Sine Kragh Petersen, Hana Matuskova, Sara Rattik, Anetta Härtlova, Anja Meissner
npj Aging and Mechanisms of Disease - 2021 -
Macrophages and scavenger receptors in obesity-associated non-alcoholic liver fatty disease
(NAFLD)
Sine Kragh Petersen, Orsolya Bilkei-Gorzo, O. Govaere, Anetta Härtlova
Scandinavian Journal of Immunology - 2020 -
Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated
macrophages.
Manman Guo, Anetta Härtlova, Marek Gierliński, Alan Prescott, Josep Castellvi, Javier Hernandez Losa, Sine Kragh Petersen, Ulf Alexander Wenzel, Brian D Dill, Christoph H Emmerich, Santiago Ramon Y Cajal, David G Russell, Matthias Trost
The EMBO journal - 2019 -
Spatiotemporal Changes of the Phagosomal Proteome in Dendritic Cells in Response to LPS
Stimulation.
Anne-Marie Pauwels, Anetta Härtlova, Julien Peltier, Yasmine Driege, Griet Baudelet, Priscille Brodin, Matthias Trost, Rudi Beyaert, Eik Hoffmann
Molecular & cellular proteomics : MCP - 2019 -
Regulation of phagosome functions by post-translational modifications: a new
paradigm.
Paul Dean, Tiaan Heunis, Anetta Härtlova, Matthias Trost
Current opinion in chemical biology - 2019 -
LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in
macrophages.
Anetta Härtlova, Susanne Herbst, Julien Peltier, Angela Rodgers, Orsolya Bilkei-Gorzo, Antony Fearns, Brian D Dill, Heyne Lee, Rowan Flynn, Sally A Cowley, Paul Davies, Patrick A Lewis, Ian G Ganley, Jennifer Martinez, Dario R Alessi, Alastair D Reith, Matthias Trost, Maximiliano G Gutierrez
The EMBO journal - 2018 -
Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor
palbociclib.
Teemu P Miettinen, Julien Peltier, Anetta Härtlova, Marek Gierliński, Valerie M Jansen, Matthias Trost, Mikael Björklund
The EMBO journal - 2018 -
Loss of the DNA Damage Repair Kinase ATM Impairs Inflammasome-Dependent Anti-Bacterial Innate
Immunity.
Saskia F Erttmann, Anetta Härtlova, Marta Sloniecka, Faizal A M Raffi, Ava Hosseinzadeh, Tomas Edgren, Reza Rofougaran, Ulrike Resch, Maria Fällman, Torben Ek, Nelson O Gekara
Immunity - 2017 -
Subversion of innate immune responses by Francisella involves the disruption of TRAF3 and TRAF6 signalling
complexes.
Daniela Putzova, Swarupa Panda, Anetta Härtlova, Jiří Stulík, Nelson O Gekara
Cellular microbiology - 2017 -
Isolation and Western Blotting of Latex-Bead Phagosomes to Track Phagosome
Maturation.
Anetta Härtlova, Julien Peltier, Orsolya Bilkei-Gorzo, Matthias Trost
Methods in molecular biology (Clifton, N.J.) - 2017 -
A mass spectrometric-derived cell surface protein
atlas.
Damaris Bausch-Fluck, Andreas Hofmann, Thomas Bock, Andreas P Frei, Ferdinando Cerciello, Andrea Jacobs, Hansjoerg Moest, Ulrich Omasits, Rebekah L Gundry, Charles Yoon, Ralph Schiess, Alexander Schmidt, Paulina Mirkowska, Anetta Härtlova, Jennifer E Van Eyk, Jean-Pierre Bourquin, Ruedi Aebersold, Kenneth R Boheler, Peter Zandstra, Bernd Wollscheid
PloS one - 2015 -
High-resolution quantitative proteome analysis reveals substantial differences between phagosomes of RAW 264.7 and bone marrow derived
macrophages.
Manman Guo, Anetta Härtlova, Brian D Dill, Alan R Prescott, Marek Gierliński, Matthias Trost
Proteomics - 2015 -
Quantitative proteome analysis of temporally resolved phagosomes following uptake via key phagocytic
receptors.
Brian D Dill, Marek Gierlinski, Anetta Härtlova, Alba González Arandilla, Manman Guo, Rosemary G Clarke, Matthias Trost
Molecular & cellular proteomics : MCP - 2015 -
Quantitative proteomics analysis of macrophage-derived lipid rafts reveals induction of autophagy pathway at the early time of Francisella tularensis LVS
infection.
Anetta Härtlova, Marek Link, Jana Balounova, Martina Benesova, Ulrike Resch, Adela Straskova, Margarita Sobol, Anatoly Philimonenko, Pavel Hozak, Zuzana Krocova, Nelson Gekara, Dominik Filipp, Jiri Stulik
Journal of proteome research - 2014 -
Application of SILAC labeling to primary bone marrow-derived dendritic cells reveals extensive GM-CSF-dependent arginine
metabolism.
Ivo Fabrik, Marek Link, Anetta Härtlova, Vera Dankova, Pavel Rehulka, Jiri Stulik
Journal of proteome research - 2014 -
Serving the new masters - dendritic cells as hosts for stealth intracellular
bacteria.
Ivo Fabrik, Anetta Härtlova, Pavel Rehulka, Jiri Stulik
Cellular microbiology - 2013 -
A proteomic view of the host-pathogen interaction: The host
perspective.
Anetta Härtlova, Zuzana Krocova, Lukas Cerveny, Jiri Stulik
Proteomics - 2011 -
Membrane rafts: a potential gateway for bacterial entry into host
cells.
Anetta Härtlova, Lukas Cerveny, Martin Hubalek, Zuzana Krocova, Jiri Stulik
Microbiology and immunology - 2010 -
Activation of B cell apoptotic pathways in the course of Francisella tularensis
infection.
Lucie Zivna, Zuzana Krocova, Anetta Härtlova, Klara Kubelkova, Jitka Zakova, Emil Rudolf, Roman Hrstka, Ales Macela, Jiri Stulik
Microbial pathogenesis - 2010 -
Interaction of B cells with intracellular pathogen Francisella
tularensis.
Zuzana Krocova, Anetta Härtlova, Dagmar Souckova, Lucie Zivna, Michal Kroca, Emil Rudolf, Ales Macela, Jiri Stulik
Microbial pathogenesis - 2008