- Home
- About
- Find staff
- Kristina Thomsson Hulthe
Kristina Thomsson Hulthe
Researcher
Core facilities-
Glycoproteoforms of Osteoarthritis-associated Lubricin in Plasma and Synovial
Fluid
Ali Reza Afshari, Vincent Chang, Kristina A Thomsson, Jennifer Höglund, Elizabeth N. Browne, George Karadzhov, Keira E. Mahoney, Taryn M. Lucas, Valentina Rangel-Angarita, Henrik Ryberg, Kamlesh Gidwani, Kim Pettersson, Ola Rolfson, Lena Björkman, Thomas Eisler, Tannin A. Schmidt, Gregory D. Jay, Stacy A. Malaker, Niclas G. Karlsson
MOLECULAR & CELLULAR PROTEOMICS - 2025 -
Gilthead seabream mucus glycosylation is complex, differs between epithelial sites and carries unusual poly N-acetylhexosamine
motifs
Kristina A Thomsson, John Benktander, Socorro Toxqui-Rodriguez, M. Carla Piazzon, Sara K. Lindén
Fish and Shellfish Immunology - 2024 -
Altered O-Glycans in stimulated whole saliva from patients with primary Sjögren's syndrome and non-pSS
sicca
Sarah Kamounah, Kristina A Thomsson, Christiane Elisabeth Sorensen, Eric Paul Bennett, Niclas G. Karlsson, Anne Marie Lynge Pedersen
SCIENTIFIC REPORTS - 2024 -
UniCarb-DB: An MS/MS Experimental Glycomic Fragmentation
Database
Chunsheng Jin, Vignesh Venkatakrishnan, Kristina A Thomsson, Nobuyuki P. Aoki, Daisuke Shinmachi, Kiyoko F. Aoki-Kinoshita, Catherine A. Hayes, Frédérique Lisacek, Niclas G. Karlsson
Methods in molecular biology (Clifton, N.J.) - 2024 -
<i>In vitro</i> fish mucosal surfaces producing mucin as a model for studying host-pathogen
interactions
Macarena P Quintana-Hayashi, Kristina A. Thomsson Hulthe, Sara K. Lindén
PLOS ONE - 2024 -
Navigating the maze of mass spectra: a machine-learning guide to identifying diagnostic ions in O-glycan
analysis
James Urban, Roman Joeres, Luc Thomes, Kristina A Thomsson, Daniel Bojar
ANALYTICAL AND BIOANALYTICAL CHEMISTRY - 2024 -
Predicting glycan structure from tandem mass spectrometry via deep
learning
James Urban, Chunsheng Jin, Kristina A Thomsson, Niclas G. Karlsson, Callum M. Ives, Elisa Fadda, Daniel Bojar
NATURE METHODS - 2024 -
Characterization of intestinal O-glycome in reactive oxygen species
deficiency
Radka Saldova, Kristina A Thomsson, Hayden Wilkinson, Maitrayee Chatterjee, Ashish K. Singh, Niclas G. Karlsson, Ulla G. Knaus
PLOS ONE - 2024 -
Characterization of MdpS: an in-depth analysis of a MUC5B-degrading protease from Streptococcus
oralis
Fredrik Leo, Rolf Lood, Kristina A Thomsson, Jonas Nilsson, Gunnel Svensater, Claes Wickstrom
FRONTIERS IN MICROBIOLOGY - 2024 -
Protein N-glycosylation in the bronchoalveolar space differs between never-smokers and long-term smokers with and without
COPD.
Vignesh Venkatakrishnan, Kristina A Thomsson, Médea Padra, Anders Andersson, Bettina Brundin, Karin Christenson, Johan Bylund, Niclas G. Karlsson, Anders Lindén, Sara K. Lindén
Glycobiology - 2023 -
Identification of Novel Glycans in the Mucus Layer of Shark and Skate
Skin
Etty Bachar-Wikstrom, Kristina A Thomsson, Carina Sihlbom, Lisa Abbo, Haitham Tartor, Sara K. Lindén, Jakob D. Wikstrom
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2023 -
Truncated lubricin glycans in osteoarthritis stimulate the synoviocyte secretion of VEGFA, IL-8, and MIP-1α: Interplay between O-linked glycosylation and inflammatory
cytokines
Shan Huang, Kristina A Thomsson, Chunsheng Jin, H. Ryberg, N. Das, A. Struglics, Ola Rolfson, L. I. Björkman, T. Eisler, T. A. Schmidt, G. D. Jay, R. Krawetz, N. G. Karlsson
Frontiers in Molecular Biosciences - 2022 -
Mucin O-glycosylation and pathogen binding ability differ between rainbow trout epithelial
sites
Kristina A Thomsson, John Benktander, Macarena P Quintana-Hayashi, Sinan Sharba, Sara K. Lindén
Fish & Shellfish Immunology - 2022 -
Sulfation of O-glycans on Mucin-type Proteins From Serous Ovarian Epithelial
Tumors.
Kristina A Thomsson, Varvara Vitiazeva, Constantina Mateoiu, Chunsheng Jin, Jining Liu, Jan Holgersson, Birgitta Weijdegård, Karin Sundfeldt, Niclas G. Karlsson
Molecular & cellular proteomics : MCP - 2021 -
The O-Glycome of Human Nigrostriatal Tissue and Its Alteration in Parkinson's
Disease
H. Wilkinson, Kristina A Thomsson, A. L. Rebelo, M. Hilliard, A. Pandit, P. M. Rudd, Niclas G. Karlsson, R. Saldova
Journal of Proteome Research - 2021 -
Cathepsin g Degrades Both Glycosylated and Unglycosylated Regions of Lubricin, a Synovial
Mucin
Shan Huang, Kristina A Thomsson, Chunsheng Jin, Sally Alweddi, A. Struglics, Ola Rolfson, Lena Björkman, S. Kalamajski, T. A. Schmidt, G. D. Jay, R. Krawetz, Niclas G. Karlsson, T. Eisler
Scientific Reports - 2020 -
Decrease of core 2 O-glycans on synovial lubricin in osteoarthritis reduces galectin-3 mediated
crosslinking.
Sarah A. Flowers, Kristina A Thomsson, Liaqat Ali, Shan Huang, Yolanda H. Mthembu, Suresh C Regmi, Jan Holgersson, Tannin A Schmidt, Ola Rolfson, Lena Björkman, Martina Sundqvist, Anna Karlsson-Bengtsson, Gregory D Jay, Thomas Eisler, Roman Krawetz, Niclas G. Karlsson
The Journal of biological chemistry - 2020 -
Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut
microbiota
H. Nagao-Kitamoto, J. L. Leslie, S. Kitamoto, Chunsheng Jin, Kristina A Thomsson, M. G. Gillilland, P. Kuffa, Y. Goto, R. R. Jenq, C. Ishii, A. Hirayama, A. M. Seekatz, E. C. Martens, K. A. Eaton, J. Y. Kao, S. Fukuda, P. D. R. Higgins, Niclas G. Karlsson, V. B. Young, N. Kamada
Nature Medicine - 2020 -
Multiple Enzyme Approach for the Characterization of Glycan Modifications on the C-Terminus of the Intestinal
MUC2Mucin.
Sjoerd van der Post, Kristina A Thomsson, Gunnar C. Hansson
Journal of proteome research - 2014 -
Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific
distribution
Jessica Holmén Larsson, Kristina A Thomsson, Ana María Rodríguez-Piñeiro, Hasse Karlsson, Gunnar C. Hansson
American Journal of Physiology-Gastrointestinal and Liver Physiology - 2013 -
Detailed O-glycomics of the Muc2 mucin from colon of wild-type, core 1- and core 3-transferase-deficient mice highlights differences compared with human
MUC2.
Kristina A Thomsson, Jessica Holmén, Jonas Ångström, Malin E V Johansson, Lijun Xia, Gunnar C. Hansson
Glycobiology - 2012 -
Proteomic study of the mucin granulae in an intestinal goblet cell
model.
Ana María Rodríguez-Piñeiro, Sjoerd van der Post, Malin E V Johansson, Kristina A Thomsson, Alexey I Nesvizhskii, Gunnar C. Hansson
Journal of proteome research - 2012 -
Composition and functional role of the mucus layers in the
intestine.
Malin E V Johansson, Daniel Ambort, Thaher Pelaseyed, André Schütte, Jenny K Gustafsson, Anna Ermund, Durai B Subramani, Jessica Holmén Larsson, Kristina A Thomsson, Joakim H. Bergström, Sjoerd van der Post, Ana María Rodríguez-Piñeiro, Henrik Sjövall, Malin Bäckström, Gunnar C. Hansson
Cellular and Molecular Life Sciences - 2011 -
Identification and quantification of mucin
expression.
Kristina A Thomsson, Gunnar C. Hansson
Methods Mol. Biol. - 2011 -
Identification and quantification of mucin
expression
Kristina A Thomsson, Gunnar C. Hansson
Methods in molecular biology (Clifton, N.J.) - 2011 -
Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in
mice.
Jianxin Fu, Bo Wei, Tao Wen, Malin E V Johansson, Xiaowei Liu, Emily Bradford, Kristina A Thomsson, Samuel McGee, Lilah Mansour, Maomeng Tong, J Michael McDaniel, Thomas J Sferra, Jerrold R Turner, Hong Chen, Gunnar C. Hansson, Jonathan Braun, Lijun Xia
The Journal of clinical investigation - 2011 -
Comparison of methods for profiling O-glycosylation: Human Proteome Organisation Human Disease Glycomics/Proteome Initiative multi-institutional study of
IgA1.
Yoshinao Wada, Anne Dell, Stuart M Haslam, Bérangère Tissot, Kévin Canis, Parastoo Azadi, Malin Bäckström, Catherine E Costello, Gunnar C. Hansson, Yoshiyuki Hiki, Mayumi Ishihara, Hiromi Ito, Kazuaki Kakehi, Niclas G. Karlsson, C E Hayes, Koichi Kato, Nana Kawasaki, Kay-Hooi Khoo, Kunihiko Kobayashi, Daniel Kolarich, Akihiro Kondo, Carlito Lebrilla, Miyako Nakano, Hisashi Narimatsu, Jan Novak, Milos V Novotny, Erina Ohno, Nicolle H Packer, Elizabeth Palaima, Matthew B Renfrow, Michiko Tajiri, Kristina A Thomsson, Hirokazu Yagi, Shin-Yi Yu, Naoyuki Taniguchi
Molecular & cellular proteomics - 2010 -
Enhanced Detection of Sialylated and Sulfated Glycans with Negative Ion Mode Nanoliquid Chromatography/Mass Spectrometry at High
pH.
Kristina A Thomsson, Malin Bäckström, Jessica Holmén Larsson, Gunnar C. Hansson, Hasse Karlsson
Analytical chemistry - 2010 -
Cervical mucins carry alpha(1,2)fucosylated glycans that partly protect from experimental vaginal
candidiasis.
Steven E Domino, Elizabeth A Hurd, Kristina A Thomsson, David M Karnak, Jessica Holmén Larsson, Elisabeth Thomsson, Malin Bäckström, Gunnar C. Hansson
Glycoconjugate journal - 2009 -
High-throughput and high-sensitivity nano-LC/MS and MS/MS for O-glycan
profiling.
Hasse Karlsson, Jessica Holmén Larsson, Kristina A Thomsson, Iris van Dijk Härd, Malin Bäckström, Gunnar C. Hansson
Methods in molecular biology (Clifton, N.J.) - 2009 -
Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp
protein.
Malin E V Johansson, Kristina A Thomsson, Gunnar C. Hansson
Journal of proteome research - 2009 -
Sensitive liquid chromatography-electrospray mass spectrometry allows for the analysis of the O-glycosylation of immunoprecipitated proteins from cells or tissues: application to MUC1 glycosylation in
cancer.
Malin Bäckström, Kristina A Thomsson, Hasse Karlsson, Gunnar C. Hansson
Journal of proteome research - 2009 -
Salivary MUC7 is a major carrier of blood group I type O-linked oligosaccharides serving as the scaffold for sialyl Lewis
x.
Niclas G. Karlsson, Kristina A Thomsson
Glycobiology - 2009 -
Large scale identification of proteins, mucins, and their O-glycosylation in the endocervical mucus during the menstrual
cycle.
Ylva Andersch-Björkman, Kristina A Thomsson, Jessica Holmén Larsson, Erling Ekerhovd, Gunnar C. Hansson
Molecular & cellular proteomics : MCP - 2007 -
MUC5B glycosylation in human saliva reflects blood group and secretor
status.
Kristina A Thomsson, Benjamin L Schulz, Nicolle H Packer, Niclas G. Karlsson
Glycobiology - 2005 -
The salivary mucin MG1 (MUC5B) carries a repertoire of unique oligosaccharides that is large and
diverse.
Kristina A Thomsson, Akraporn Prakobphol, Hakon Leffler, Molakala S Reddy, Michael J Levine, Susan J Fisher, Gunnar C. Hansson
Glycobiology - 2002 -
Intestinal mucins from cystic fibrosis mice show increased fucosylation due to an induced Fucalpha1-2
glycosyltransferase.
Kristina A Thomsson, Marina Hinojosa-Kurtzberg, Karin A Axelsson, Steven E Domino, John B Lowe, Sandra J Gendler, Gunnar C. Hansson
The Biochemical journal - 2002 -
Analytical approaches to the study of mucin
glycosylation
Kristina A Thomsson
2000 -
Sequencing of sulfated oligosaccharides from mucins by liquid chromatography and electrospray ionization tandem mass
spectrometry.
Kristina A Thomsson, H Karlsson, Gunnar C. Hansson
Analytical chemistry - 2000 -
Liquid chromatography-electrospray mass spectrometry as a tool for the analysis of sulfated oligosaccharides from mucin
glycoproteins.
Kristina A Thomsson, Niclas G. Karlsson, Gunnar C. Hansson
Journal of chromatography. A - 1999 -
Different O-glycosylation of respiratory mucin glycopeptides from a patient with cystic
fibrosis.
Kristina A Thomsson, I Carlstedt, Niclas G. Karlsson, Hasse Karlsson, Gunnar C. Hansson
Glycoconjugate journal - 1998 -
Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand
activity.
A Prakobphol, Kristina A Thomsson, Gunnar C. Hansson, S D Rosen, M S Singer, N J Phillips, K F Medzihradszky, A L Burlingame, H Leffler, S J Fisher
Biochemistry - 1998