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- Fredrik Anesten
Fredrik Anesten
Researcher
Department of PharmacologyAffiliated to Research
Department of Physiology-
The effect of increased weight loading on body weight is partly dependent on Piezo1 in osteoblast-lineage cells and TrkA
signaling.
Daniel Hägg, Lei Li, Alec T Beeve, Erica L Scheller, Jakob Bellman, Fredrik Anesten, Jovana Zlatkovic, Adrià Dalmau Gasull, Ferran Font, Sofia Moverare Skrtic, John-Olov Jansson, Claes Ohlsson
Scientific reports - 2026 -
Body weight reduction by increased weight loading in mice is associated with sensory signaling in the dorsal horn of the lumbar spinal
cord.
Fredrik Anesten, Jovana Zlatkovic, Claes Ohlsson, Line Sofie Löken, Daniel Hägg, John-Olov Jansson
Neuroscience - 2025 -
Increased weight-bearing load reduces biological body weight while sodium and water balances are
unaffected
Jovana Zlatkovic, Jakob Bellman, Daniel Hägg, Mathilda Magnusson, Claes Ohlsson, Gerald DiBona, Fredrik Anesten, John-Olov Jansson
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY - 2025 -
The dual hypothesis of homeostatic body weight regulation, including gravity-dependent and leptin-dependent
actions.
John-Olov Jansson, Fredrik Anesten, Daniel Hägg, Jovana Zlatowic, Suzanne L. Dickson, Per-Anders Jansson, Erik Schéle, Jakob Bellman, Claes Ohlsson
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 2023 -
Reduction of body weight by increased loading is associated with activation of norepinephrine neurones in the medial nucleus of the solitary
tract.
Jovana Zlatkovic, Adrià Dalmau Gasull, Daniel Hägg, Ferran Font Gironès, Jakob Bellman, Björn Meister, Vilborg Palsdottir, Johan Ruud, Claes Ohlsson, Suzanne L. Dickson, Fredrik Anesten, John-Olov Jansson
Journal of neuroendocrinology - 2023 -
A Body Weight Sensor Regulates Prepubertal Growth via the Somatotropic Axis in Male
Rats
John-Olov Jansson, Adria Dalmau Gasull, Erik Schele, Suzanne L. Dickson, Vilborg Palsdottir, Anders Palmquist, Ferran Font Gironès, Jakob Bellman, Fredrik Anesten, Daniel Hägg, Claes Ohlsson
Endocrinology - 2021 -
Glucagon-Like Peptide-1-, but not Growth and Differentiation Factor 15-, Receptor Activation Increases the Number of Interleukin-6-Expressing Cells in the External Lateral Parabrachial
Nucleus
Fredrik Anesten, Devesh Mishra, Adria Dalmau Gasull, Linda Engström Ruud, Jakob Bellman, Vilborg Palsdottir, F Zhang, S. Trapp, Karolina P Skibicka, Matti Poutanen, John-Olov Jansson
Neuroendocrinology - 2019 -
Interleukin-6 in the central amygdala is bioactive and co-localised with glucagon-like peptide-1
receptor
Fredrik Anesten, Adria Dalmau Gasull, Jennifer E. Richard, Imre Farkas, Devesh Mishra, Lilly Taing, F. Zhang, Matti Poutanen, Vilborg Palsdottir, Z. Liposits, Karolina P Skibicka, John-Olov Jansson
Journal of Neuroendocrinology - 2019 -
Body weight homeostat that regulates fat mass independently of leptin in rats and
mice.
John-Olov Jansson, Vilborg Palsdottir, Daniel Hägg, Erik Schéle, Suzanne L. Dickson, Fredrik Anesten, Tina Bake, Mikael Montelius, Jakob Bellman, Maria E I Johansson, Roger D Cone, Daniel J Drucker, Jianyao Wu, Biljana Aleksic, Anna E Törnqvist, Klara Sjögren, Jan-Åke Gustafsson, Sara H Windahl, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2018 -
Interleukin-6 is important for regulation of core body temperature during long-term cold exposure in
mice
Emil Egecioglu, Fredrik Anesten, Erik Schéle, Vilborg Palsdottir
Biomedical Reports - 2018 -
Functional interleukin-6 receptor- is located in tanycytes at the base of the third
ventricle
Fredrik Anesten, Cristiano Santos, Edwin Gidestrand, Erik Schéle, Vilborg Palsdottir, Teodor Swedung-Wettervik, B. Meister, Karolina P Skibicka, John-Olov Jansson
Journal of Neuroendocrinology - 2017 -
Preproglucagon neurons in the hindbrain have IL-6 receptor-α and show Ca2+ influx in response to
IL-6
Fredrik Anesten, M. K. Holt, Erik Schéle, Vilborg Palsdottir, F. Reimann, F. M. Gribble, Cecilia Safari, Karolina P Skibicka, S. Trapp, John-Olov Jansson
American Journal of Physiology. Regulatory Integrative and Comparative Physiology - 2016 -
Regulation of body fat mass by the gut microbiota: Possible mediation by the
brain.
Erik Schéle, Louise Grahnemo, Fredrik Anesten, Anna Hallén, Fredrik Bäckhed, John-Olov Jansson
Peptides - 2016 -
IL-6 and GLP-1 in body fat regulating parts of the CNS in healthy
mice
Fredrik Anesten
2016 -
The androgen receptor confers protection against diet-induced atherosclerosis, obesity, and dyslipidemia in female
mice.
Johan Bourghardt Fagman, Anna S K Wilhelmson, Benedetta Maria Motta, Carlo Pirazzi, Camilla Alexanderson, Karel De Gendt, Guido Verhoeven, Agneta Holmäng, Fredrik Anesten, John-Olov Jansson, Malin Levin, Jan Borén, Claes Ohlsson, Alexandra Krettek, Stefano Romeo, Åsa Tivesten
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2015 -
GLP-1 Receptor Stimulation of the Lateral Parabrachial Nucleus Reduces Food Intake: Neuroanatomical, Electrophysiological, and Behavioral
Evidence
Jennifer E. Richard, I. Farkas, Fredrik Anesten, Rozita H Anderberg, Suzanne L. Dickson, F. M. Gribble, F. Reimann, John-Olov Jansson, Z. Liposits, Karolina P Skibicka
Endocrinology - 2014 -
The gut microbiota reduces leptin sensitivity and the expression of the obesity-suppressing neuropeptides proglucagon (Gcg) and brain-derived neurotrophic factor (Bdnf) in the central nervous
system.
Erik Schéle, Louise Grahnemo, Fredrik Anesten, Anna Hallén, Fredrik Bäckhed, John-Olov Jansson
Endocrinology - 2013 -
Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and
IL-6
Rozita H. Shirazi, Vilborg Palsdottir, Jim Collander, Fredrik Anesten, Heike Vogel, F. Langlet, A. Jaschke, A. Schurmann, V. Prevot, Linus Ruijin Shao, John-Olov Jansson, Karolina P Skibicka
Proceedings of the National Academy of Sciences of the United States of America - 2013 -
Interrelation between interleukin-1 (IL-1), IL-6 and body fat regulating circuits of the hypothalamic arcuate
nucleus.
Erik Schéle, Anna Benrick, Louise Grahnemo, Emil Egecioglu, Fredrik Anesten, Vilborg Palsdottir, John-Olov Jansson
Journal of neuroendocrinology - 2013