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- Lena Öhman
Lena Öhman
Professor
Avd för mikrobiologi och immunologiAvd-/Sektionschef, Inst
Avd för mikrobiologi och immunologi-
Anti-integrin αvβ6 IgG antibody as a diagnostic and prognostic marker in ulcerative colitis: A cross-sectional and longitudinal study defining a specific disease
phenotype.
Eleftheria Pertsinidou, Benita Salomon, Daniel Bergemalm, Samira Salihovic, Charlotte R H Hedin, Maria Ling Lundström, Åsa V Keita, Maria K Magnusson, Carl Eriksson, May-Bente Bengtson, Olle Grännö, Tone B Aabrekk, Robert Movérare, Niclas Rydell, Helena Ekoff, Johan Rönnelid, Mauro D'Amato, Trond E Detlie, Gert Huppertz-Hauss, Randi Opheim, Petr Ricanek, Vendel A Kristensen, Lena Öhman, Johan D Söderholm, Robert Kruse, Carl M Lindqvist, Marie Carlson, Dirk Repsilber, Marte L Høivik, Jonas Halfvarson
Journal of Crohn's and Colitis - 2025 -
Cohort profile: the Swedish Inception Cohort in inflammatory bowel disease
(SIC-IBD)
Benita Salomon, Olle Granno, Daniel Bergemalm, Hans Strid, Adam Carstens, Henrik Hjortswang, Maria Ling Lundstrom, Johann P. Hreinsson, Sven Almer, Franscesca Bresso, Carl Eriksson, Olof Grip, Andre Blomberg, Jan Marsal, Niloofar Nikaein, Shoaib Bakhtyar, Carl Marten Lindqvist, Elisabeth Hultgren Hornquist, Maria K Magnusson, Asa Keita, Mauro D'Amato, Dirk Repsilber, Lena Öhman, Johan D. Soderholm, Marie Carlson, Charlotte R. H. Hedin, Robert Kruse, Jonas Halfvarson
BMJ OPEN - 2025 -
Gut microbiota development across the lifespan: Disease links and health-promoting
interventions
Ida Schoultz, Marcus J. Claesson, Maria Gloria Dominguez-Bello, Frida Fak Hallenius, Peter Konturek, Katri Korpela, Martin Frederik Laursen, John Penders, H. Roager, Tommi Vatanen, Lena Öhman, Maria C. Jenmalm
JOURNAL OF INTERNAL MEDICINE - 2025 -
Elevated Fecal Biomarkers of Colo-Rectal Epithelial Cell Activity in Irritable Bowel
Syndrome
Per Venge, Valeria Castro Tejera, Christer Petersson, Shengyuan Xu, Anders Larsson, Magnus Simrén, Lena Öhman, Hans Törnblom
Neurogastroenterology and Motility - 2025 -
Preclinical Protein Signatures of Crohn's Disease and Ulcerative Colitis: A Nested Case-Control Study Within Large Population-Based
Cohorts
Olle Granno, Daniel Bergemalm, Benita Salomon, Carl Marten Lindqvist, Charlotte R. H. Hedin, Marie Carlson, Katharina Dannenberg, Erik Andersson, Asa Keita, Maria K Magnusson, Carl Eriksson, Vivekananda Lanka, Patrik K. E. Magnusson, Mauro D'Amato, Lena Öhman, Johan D. Soderholm, Johan Hultdin, Robert Kruse, Yang Cao, Dirk Repsilber, Olof Grip, Pontus Karling, Jonas Halfvarson
GASTROENTEROLOGY - 2025 -
Laparoscopic lavage in a purulent peritonitis model: impact on inflammatory
proteins
Erik Sinclair, Maria K Magnusson, Eva Angenete, Mattias Prytz, Viktor Tasselius, Lena Öhman, Eva Haglind
EUROPEAN JOURNAL OF MEDICAL RESEARCH - 2025 -
Faecal biomarkers for diagnosis and prediction of disease course in treatment-naïve patients with
IBD
Maria Ling Lundström, Christer Peterson, Charlotte R.H. Hedin, Daniel Bergemalm, Maria Lampinen, Maria K Magnusson, Åsa V. Keita, Robert Kruse, Carl Mårten Lindqvist, Dirk Repsilber, Mauro D'Amato, Henrik Hjortswang, Hans Strid, Johan D. Söderholm, Lena Öhman, Per Venge, Jonas Halfvarson, Marie Carlson
Alimentary Pharmacology and Therapeutics - 2024 -
Exposure of Colon-Derived Epithelial Monolayers to Fecal Luminal Factors from Patients with Colon Cancer and Ulcerative Colitis Results in Distinct Gene Expression
Patterns
Maria K Magnusson, Anna Bas-Forsberg, Alexandra Verveda, Maria Sapnara, Julie Lorent, Otto Savolainen, Yvonne Wettergren, Hans Strid, Magnus Simrén, Lena Öhman
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2024 -
Predictors of symptom trajectory in newly diagnosed ulcerative colitis: a 3-year follow-up cohort
study.
Maaike Van Den Houte, Livia Guadagnoli, Lena Öhman, Anders Bergstedt, Berndt Zeijlemaker Johansson, Magnus Simrén, Hans Strid, Lukas Van Oudenhove, Jan Svedlund
Journal of Crohn's and Colitis - 2024 -
Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel
disease
Samira Salihovic, Niklas Nystrom, Charlotte Bache-Wiig Mathisen, Robert Kruse, Christine Olbjorn, Svend Andersen, Alexandra J. Noble, Maria Dorn-Rasmussen, Igor Bazov, Gori Perminow, Randi Opheim, Trond Espen Detlie, Gert Huppertz-Hauss, Charlotte R. H. Hedin, Marie Carlson, Lena Öhman, Maria K Magnusson, Asa V. Keita, Johan D. Soderholm, Mauro D'Amato, Matej Oresic, Vibeke Wewer, Jack Satsangi, Carl Marten Lindqvist, Johan Burisch, Holm H. Uhlig, Dirk Repsilber, Tuulia Hyotylainen, Marte Lie Hoivik, Jonas Halfvarson
NATURE COMMUNICATIONS - 2024 -
Temporal stability of fecal metabolomic profiles in irritable bowel
syndrome
Cristina Iribarren, Otto Savolainen, Maria Sapnara, Hans Törnblom, Magnus Simrén, Maria K Magnusson, Lena Öhman
Neurogastroenterology and Motility - 2024 -
Fecal Supernatants from Patients with Crohn's Disease Induce Inflammatory Alterations in M2 Macrophages and
Fibroblasts
Frida Gorreja, Mia Bendix, Stephen T. A. Rush, Lujain Maasfeh, Otto Savolainen, Anders Dige, Jorgen Agnholt, Lena Öhman, Maria K Magnusson
CELLS - 2024 -
Fecal Biomarkers of Neutrophil and Eosinophil Origin Reflect the Response to Biological Therapy and Corticosteroids in Patients With Inflammatory Bowel
Disease
Maria Ling Lundström, Christer Peterson, Maria Lampinen, Charlotte R.H. Hedin, Åsa V. Keita, Robert Kruse, Maria K Magnusson, Carl Mårten Lindqvist, Dirk Repsilber, Mauro D'Amato, Henrik Hjortswang, Hans Strid, Anders Rönnblom, Johan D. Söderholm, Lena Öhman, Per Venge, Jonas Halfvarson, Marie Carlson
Clinical and translational gastroenterology - 2023 -
Health-related quality of life in patients with long-standing ulcerative colitis in
remission
Georgios Mavroudis, Magnus Simrén, Lena Öhman, Hans Strid
Therapeutic Advances in Gastroenterology - 2022 -
Differences in Metabolite Composition of Aloe barbadensis Mill. Extracts Lead to Differential Effects on Human Blood T Cell Activity In
Vitro.
Bani Ahluwalia, Maria K Magnusson, Fredrik Larsson, Otto Savolainen, Alastair B Ross, Lena Öhman
Molecules (Basel, Switzerland) - 2022 -
Downregulated Mucosal Autophagy, Alpha Kinase-1 and IL-17 Signaling Pathways in Active and Quiescent Ulcerative
Colitis.
Luiza Moraes Holst, Jonas Halfvarson, Marie Carlson, Charlotte Hedin, Robert Kruse, Carl Mårten Lindqvist, Daniel Bergemalm, Sven Almér, Francesca Bresso, Maria Ling Lundström, Dirk Repsilber, Mauro D'Amato, Åsa Keita, Henrik Hjortswang, Johan Söderholm, Johanna Sundin, Hans Törnblom, Magnus Simrén, Hans Strid, Maria K Magnusson, Lena Öhman
Clinical and experimental gastroenterology - 2022 -
Predictors of Symptom-Specific Treatment Response to Dietary Interventions in Irritable Bowel
Syndrome
Esther Colomier, L. Van Oudenhove, J. Tack, Lena Böhn, Sean Bennet, Sanna Nybacka, Stine Störsrud, Lena Öhman, Hans Törnblom, Magnus Simrén
Nutrients - 2022 -
Fecal Luminal Factors from Patients with Gastrointestinal Diseases Alter Gene Expression Profiles in Caco-2 Cells and
Colonoids
Luiza Moraes Holst, Cristina Iribarren, Maria Sapnara, O. Savolainen, Hans Törnblom, Yvonne Wettergren, H. Strid, Magnus Simrén, Maria K Magnusson, Lena Öhman
International Journal of Molecular Sciences - 2022 -
Randomised controlled trial: effects of gluten-free diet on symptoms and the gut microenvironment in irritable bowel
syndrome
Joost Algera, Maria K Magnusson, Lena Öhman, Stine Störsrud, Magnus Simrén, Hans Törnblom
Alimentary Pharmacology and Therapeutics - 2022 -
Randomised clinical trial and meta-analysis: mesalazine treatment in irritable bowel syndrome-Effects on gastrointestinal symptoms and rectal biomarkers of immune
activity
Valeria Castro Tejera, Lena Öhman, L. Aabakken, B. Fellstrom, T. Hausken, O. Hovde, Johann P. Hreinsson, G. Lindberg, P. Venge, Magnus Simrén, Hans Törnblom
Alimentary Pharmacology & Therapeutics - 2022 -
Fecal luminal factors from patients with irritable bowel syndrome induce distinct gene expression of
colonoids
Cristina Iribarren, Sofia Nordlander, Johanna Sundin, Stefan Isaksson, O. Savolainen, Hans Törnblom, Maria K Magnusson, Magnus Simrén, Lena Öhman
Neurogastroenterology and Motility - 2022 -
A novel stepwise integrative analysis pipeline reveals distinct microbiota-host interactions and link to symptoms in irritable bowel
syndrome
Annikka Polster, Lena Öhman, J. Tap, M. Derrien, B. Le Neve, Johanna Sundin, Hans Törnblom, Marija Cvijovic, Magnus Simrén
Scientific Reports - 2021 -
Impaired Luminal Control of Intestinal Macrophage Maturation in Patients With Ulcerative Colitis During
Remission
Lujain Maasfeh, Anetta Härtlova, Stefan Isaksson, Johanna Sundin, G. Mavroudis, O. Savolainen, H. Strid, Lena Öhman, Maria K Magnusson
Cellular and Molecular Gastroenterology and Hepatology - 2021 -
Aloe barbadensis Mill. extract improves symptoms in IBS patients with diarrhoea: post hoc analysis of two randomized double-blind controlled
studies
Bani Ahluwalia, Maria K Magnusson, Lena Böhn, Stine Störsrud, F. Larsson, Lena Öhman, Magnus Simrén
Therapeutic Advances in Gastroenterology - 2021 -
Fecal microbiota dynamics during disease activity and remission in newly diagnosed and established ulcerative
colitis
Lena Öhman, A. Lasson, Anna Strömbeck, Stefan Isaksson, Marcus Hesselmar, Magnus Simrén, H. Strid, Maria K Magnusson
Scientific Reports - 2021 -
Diet and gut microbiome interactions of relevance for symptoms in irritable bowel
syndrome
J. Tap, Stine Störsrud, B. Le Neve, A. Cotillard, N. Pons, J. Dore, Lena Öhman, Hans Törnblom, M. Derrien, Magnus Simrén
Microbiome - 2021 -
The Effects of Human Milk Oligosaccharides on Gut Microbiota, Metabolite Profiles and Host Mucosal Response in Patients with Irritable Bowel
Syndrome
Cristina Iribarren, Maria K Magnusson, L. K. Vigsnaes, Imran Aziz, I. D. Amundsen, T. Suligoj, N. Juge, Piyush Patel, Maria Sapnara, L. Johnsen, N. Sorensen, Johanna Sundin, Hans Törnblom, Magnus Simrén, Lena Öhman
Nutrients - 2021 -
A Distinct Faecal Microbiota and Metabolite Profile Linked to Bowel Habits in Patients with Irritable Bowel
Syndrome
Bani Ahluwalia, Cristina Iribarren, Maria K Magnusson, Johanna Sundin, Egbert Clevers, O. Savolainen, A. B. Ross, Hans Törnblom, Magnus Simrén, Lena Öhman
Cells - 2021 -
Impaired Butyrate Induced Regulation of T Cell Surface Expression of CTLA-4 in Patients with Ulcerative
Colitis
Maria K Magnusson, A. Vidal, Lujain Maasfeh, Stefan Isaksson, R. Malhotra, H. K. Olsson, Lena Öhman
International Journal of Molecular Sciences - 2021 -
Systemic Inflammatory Protein Profiles Distinguish Irritable Bowel Syndrome (IBS) and Ulcerative Colitis, Irrespective of Inflammation or IBS-Like
Symptoms.
Luiza Moraes, Maria K Magnusson, Georgios Mavroudis, Annikka Polster, Börje Jonefjäll, Hans Törnblom, Johanna Sundin, Magnus Simrén, Hans Strid, Lena Öhman
Inflammatory bowel diseases - 2020 -
Human milk oligosaccharide supplementation in irritable bowel syndrome patients: A parallel, randomized, double-blind, placebo-controlled
study
Cristina Iribarren, Hans Törnblom, Imran Aziz, Maria K Magnusson, Johanna Sundin, L. K. Vigsnaes, I. D. Amundsen, B. McConnell, D. Seitzberg, Lena Öhman, Magnus Simrén
Neurogastroenterology and Motility - 2020 -
Fecal microbiota composition is linked to the postoperative disease course in patients with Crohn's
disease
Anna Strömbeck, Anders Lasson, H. Strid, Johanna Sundin, P. O. Stotzer, Magnus Simrén, Maria K Magnusson, Lena Öhman
BMC Gastroenterology - 2020 -
Randomized clinical trial: Effects of Aloe barbadensis Mill. extract on symptoms, fecal microbiota and fecal metabolite profiles in patients with irritable bowel
syndrome
Bani Ahluwalia, Maria K Magnusson, Lena Böhn, Stine Störsrud, F. Larsson, O. Savolainen, A. Ross, Magnus Simrén, Lena Öhman
Neurogastroenterology and Motility - 2020 -
Evidence of altered mucosa-associated and fecal microbiota composition in patients with Irritable Bowel
Syndrome
Johanna Sundin, Imran Aziz, Sofia Nordlander, Annikka Polster, Y. O. O. Hu, L. W. Hugerth, A. A. L. Pennhag, L. Engstrand, Hans Törnblom, Magnus Simrén, Lena Öhman
Scientific Reports - 2020 -
The Anti-inflammatory Immune Regulation Induced by Butyrate Is Impaired in Inflamed Intestinal Mucosa from Patients with Ulcerative
Colitis.
Maria K Magnusson, Stefan Isaksson, Lena Öhman
Inflammation - 2020 -
Evidence for an association of gut microbial Clostridia with brain functional connectivity and gastrointestinal sensorimotor function in patients with irritable bowel syndrome, based on tripartite network
analysis
Jennifer S. Labus, Vadim Osadchiy, Elaine Y. Hsiao, Julien Tap, Muriel Derrien, Arpana Gupta, Kirsten Tillisch, Boris Le Neve, Cecilia Grinsvall, Maria Ljungberg, Lena Öhman, Hans Törnblom, Magnus Simrén, Emeran A. Mayer
MICROBIOME - 2019 -
A distinct gut microbiota composition in patients with ankylosing spondylitis is associated with increased levels of fecal
calprotectin
Eva Klingberg, Maria K Magnusson, Hans Strid, Anna Deminger, Arne Ståhl, Johanna Sundin, Magnus Simrén, Hans Carlsten, Lena Öhman, Helena Forsblad d'Elia
Arthritis Research & Therapy - 2019 -
Colonic mast cell numbers, symptom profile, and mucosal expression of elements of the epithelial barrier in irritable bowel
syndrome
Johanna Sundin, Sofia Nordlander, H. Eutamene, V. Alquier-Bacquie, C. Cartier, V. Theodorou, B. Le Neve, Hans Törnblom, Magnus Simrén, Lena Öhman
Neurogastroenterology and Motility - 2019 -
Mucosal and Systemic Immune Profiles Differ During Early and Late Phases of the Disease in Patients With Active Ulcerative
Colitis
Georgios Mavroudis, Maria K Magnusson, Stefan Isaksson, Johanna Sundin, Magnus Simrén, Lena Öhman, Hans Strid
Journal of Crohns & Colitis - 2019 -
Fasting breath H-2 and gut microbiota metabolic potential are associated with the response to a fermented milk product in irritable bowel
syndrome
M. Derrien, J. Tap, R. Brazeilles, S. C. Portier, D. Guyonnet, Lena Öhman, Stine Störsrud, Hans Törnblom, Magnus Simrén
Plos One - 2019 -
Rome Foundation Working Team Report on Post-Infection Irritable Bowel
Syndrome
G. Barbara, M. Grover, P. Bercik, M. Corsetti, U. C. Ghoshal, Lena Öhman, M. Rajilic-Stojanovic
Gastroenterology - 2019 -
Subgroups of IBS patients are characterized by specific, reproducible profiles of GI and non-GI symptoms and report differences in healthcare utilization: A population-based
study
Annikka Polster, O. S. Palsson, Hans Törnblom, Lena Öhman, A. D. Sperber, W. E. Whitehead, Magnus Simrén
Neurogastroenterology and Motility - 2019 -
Symptoms compatible with functional bowel disorders are common in patients with quiescent ulcerative colitis and influence the quality of life but not the course of the
disease
Georgios Mavroudis, Magnus Simrén, Börje Jonefjäll, Lena Öhman, Hans Strid
Therapeutic Advances in Gastroenterology - 2019 -
Effects of the long-term storage of human fecal microbiota samples collected in
RNAlater
J. Tap, S. Cools-Portier, S. Pavan, A. Druesne, Lena Öhman, Hans Törnblom, Magnus Simrén, M. Derrien
Scientific Reports - 2019 -
Evidence of increased fecal granins in children with irritable bowel syndrome and correlates with
symptoms
R. J. Shulman, Lena Öhman, M. Stridsberg, K. Cain, Magnus Simrén, M. Heitkemper
Neurogastroenterology and Motility - 2019 -
Heart rate variability characteristics of patients with irritable bowel syndrome and associations with
symptoms
Annikka Polster, Peter Friberg, Veronica Gunterberg, Lena Öhman, B. Le Neve, Hans Törnblom, Marija Cvijovic, Magnus Simrén
Neurogastroenterology and Motility - 2018 -
Fecal chromogranins and secretogranins are linked to the fecal and mucosal intestinal bacterial composition of IBS patients and healthy
subjects
Johanna Sundin, M. Stridsberg, J. Tap, M. Derrien, B. Le Nevé, J. Doré, Hans Törnblom, Magnus Simrén, Lena Öhman
Scientific Reports - 2018 -
Effects of Anti-TNFα Treatment on Mucosal Expression of IL-17A, IL-21, and IL-22 and Cytokine-Producing T Cell Subsets in Crohn's
Disease
A. Dige, M. K. Magnusson, C. Uhrenholt, T. K. Rasmussen, T. Kragstrup, Lena Öhman, J. Dahlerup, J. Agnholt
Mediators of Inflammation - 2018 -
Neither self-reported atopy nor IgE-mediated allergy are linked to gastrointestinal symptoms in patients with irritable bowel
syndrome
Sanna Nybacka, Lena Öhman, Stine Störsrud, Mathilda Mybeck, Lena Böhn, Katarina Wilpart, Anna Winkvist, Ulf Bengtsson, Hans Törnblom, Magnus Simrén
Neurogastroenterology and Motility - 2018 -
Systemic cytokines are elevated in a subset of patients with irritable bowel syndrome but largely unrelated to symptom
characteristics
Sean Bennet, O. Palsson, W. E. Whitehead, D. A. Barrow, Hans Törnblom, Lena Öhman, Magnus Simrén, M. A. L. van Tilburg
Neurogastroenterology and Motility - 2018
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