The course in Advanced Medicinal Chemistry will provide in-depth knowledge of the design, synthesis and biological evaluation of small organic substances as potential lead compounds.
After completing the course, you should be able to
- describe strategies for the design and synthesis of potential lead compounds
- explain important methods and theories for the design and synthesis of lead compounds
- describe methods for biological evaluation of substances
- use computer-based methods (computational chemistry) to design potential lead compounds and to study and solve drug-chemical problems
- perform basic retro-synthetic analysis
- propose synthetic methods for drug substances
- explain important methods and theories for evaluation of lead compounds and apply them to specific cases
- critically analyse scientific publications
- explain and discuss your conclusions, as well as the knowledge and arguments that underlie them, both orally and in writing.
The knowledge obtained in this course is necessary for continued higher studies in medicinal chemistry.
The course is divided into lectures, group exercises, project assignments, computer labs and literature seminars. Group exercises, project assignments, computer labs and seminars are mandatory.