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- Jingjing Zhang
Jingjing Zhang
Postdoctor
Department of Chemistry & Molecular Biology-
Therapeutic Potential of STE20-Type Kinase STK25 Inhibition for the Prevention and Treatment of Metabolically Induced Hepatocellular
Carcinoma
Ying Xia, Mara Caputo, Emma Andersson, Bernice Asiedu, Jingjing Zhang, Wei Hou, Manoj Amrutkar, Emmelie Cansby, Nadia Gul, Anne Gemmink, Caitlyn Myers, Mariam Aghajan, Sheri Booten, Andrew J. Hoy, Anetta Härtlova, Per Lindahl, Anders Ståhlberg, Gert Schaart, Matthijs K. C. Hesselink, Andreas Peter, Sue Murray, Margit Mahlapuu
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY - 2025 -
Caenorhabditis elegans telomere- binding proteins TEBP-1 and TEBP-2 adapt the Myb module to dimerize and bind telomeric
DNA
Shilpa Padmanaban, Nils Lambacher, Valerie M. Tesmer, Jingjing Zhang, Hiroki Shibuya, Jayakrishnan Nandakumar
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA - 2024 -
Regulation of meiotic telomere dynamics through membrane fluidity promoted by
AdipoR2-ELOVL2
Jingjing Zhang, Mario Ruiz, Per-Olof Bergh, Marcus Henricsson, Nena Stojanovic, Ranjan Devkota, Marius Henn, Mohammad Bohlooly-Y, Abrahan Hernandez-Hernandez, Manfred Alsheimer, Jan Borén, Marc Pilon, Hiroki Shibuya
NATURE COMMUNICATIONS - 2024 -
MEILB2-BRME1 forms a V-shaped DNA clamp upon BRCA2-binding in meiotic
recombination
Manickam Gurusaran, Jingjing Zhang, Kexin Zhang, Hiroki Shibuya, Owen R. Davies
NATURE COMMUNICATIONS - 2024 -
1700029I15Rik orchestrates the biosynthesis of acrosomal membrane proteins required for sperm-egg
interaction.
Yonggang Lu, Kentaro Shimada, Shaogeng Tang, Jingjing Zhang, Yo Ogawa, Taichi Noda, Hiroki Shibuya, Masahito Ikawa
Proceedings of the National Academy of Sciences of the United States of America - 2023 -
Structure of a meiosis-specific complex central to BRCA2 localization at recombination
sites.
Devon F Pendlebury, Jingjing Zhang, Ritvija Agrawal, Hiroki Shibuya, Jayakrishnan Nandakumar
Nature structural & molecular biology - 2021 -
BRCA2 in mammalian
meiosis.
Jingjing Zhang, Jayakrishnan Nandakumar, Hiroki Shibuya
Trends in cell biology - 2021 -
Telomeric double-strand DNA-binding proteins DTN-1 and DTN-2 ensure germline immortality in Caenorhabditis
elegans.
Io Yamamoto, Kexin Zhang, Jingjing Zhang, Egor Vorontsov, Hiroki Shibuya
eLife - 2021 -
Identification of novel BRCA2-binding proteins that are essential for meiotic homologous
recombination
Jingjing Zhang
2021 -
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer
cells.
Jingjing Zhang, Manickam Gurusaran, Yasuhiro Fujiwara, Kexin Zhang, Meriem Echbarthi, Egor Vorontsov, Rui Guo, Devon F Pendlebury, Intekhab Alam, Gabriel Livera, Martini Emmanuelle, P Jeremy Wang, Jayakrishnan Nandakumar, Owen R Davies, Hiroki Shibuya
Nature communications - 2020 -
A meiosis-specific BRCA2 binding protein recruits recombinases to DNA double-strand breaks to ensure homologous
recombination.
Jingjing Zhang, Yasuhiro Fujiwara, Shohei Yamamoto, Hiroki Shibuya
Nature communications - 2019 -
Distinct TERB1 Domains Regulate Different Protein Interactions in Meiotic Telomere
Movement.
Jingjing Zhang, Zhaowei Tu, Yoshinori Watanabe, Hiroki Shibuya
Cell reports - 2017 -
MASTL is essential for anaphase entry of proliferating primordial germ cells and establishment of female germ cells in
mice
Sanjiv Risal, Jingjing Zhang, D. Adhikari, X. M. Liu, Jingchen Shao, Kiran Busayavalasa, Zhaowei Tu, Z. J. Chen, P. Kaldis, Kui Liu
Cell Discovery - 2017 -
Speedy A-Cdk2 binding mediates initial telomere-nuclear envelope attachment during meiotic prophase I independent of Cdk2
activation
Zhaowei Tu, M. B. Bayazit, H. B. Liu, Jingjing Zhang, Kiran Busayavalasa, Sanjiv Risal, Jingchen Shao, A. Satyanarayana, V. Coppola, L. Tessarollo, M. Singh, Chunwei Zheng, C. S. Han, Z. J. Chen, P. Kaldis, J. A. Gustafsson, Kui Liu
Proceedings of the National Academy of Sciences of the United States of America - 2017 -
Inhibitory phosphorylation of Cdk1 mediates prolonged prophase I arrest in female germ cells and is essential for female reproductive
lifespan
Deepak Adhikari, Kiran Busayavalasa, Jingjing Zhang, Mengwen Hu, Sanjiv Risal, Mustafa Bilal Bayazit, Meenakshi Singh, M. Kasim Diril, Philipp Kaldis, Kui Liu
Cell Research - 2016